In this review paper, the authors have presented a brief conceptual
summary of the applications of biofuel cell in general and enzymatic one in
special with a short historical background, rather than their design and
operation. Greater emphasis has been given to the recent progress in the
development of biofuel cells and their applications for powering
bioelectronic devices. Importance of electronic management of the energy
derived from biological sources and interfacing enzyme-based biofuel cells
with power consuming microelectronic devices have also been discussed
briefly. The applications of the enzyme in the advancement of anode and
cathode of biofuel cells based on the classification of single-enzyme and
multi-enzyme catalysis system have also been briefly reviewed. In addition,
the role of nanotechnology accompanied with redox mediators in
enhancing the power output of enzymatic biofuel cells has been discussed
with the help of some notable research efforts made recently with a
particular emphasis on some of the latest and most imperative
breakthroughs in EBFCs design based on buckypapers and carbon
nanodots.