Country characteristics World population: 7.800.000.000 U.S. population: 328.239.523 (Census) Global cases: 94.544.494 U.S. Cases: 23.758.856 Global deaths: 2.023.658 U.S. Deaths: 395.851 References: U.S. Census Bureau (2019), American Community Survey. Retrieved from https://data.census.gov/cedsci/table?q=population&tid=ACSDT1Y2019.B01003&hidePreview=true Dong E, Du H, Gardner L (2020), An interactive web-based dashboard to track COVID-19 in real time, Lance Infect Dis; published online February 2019. https://doi.org/10.1016/S1473-3099(20)30120-1. COVID-19 Vaccines Authorized for Emergency Use: Approval of vaccine by: FDA (U.S. Food and Dug Administration’s Center for Biologics Evaluation and Research (CBER) Vaccine Approved or licenses PfizerBioNTech COVID-19 Vaccine No Moderna COVID-19 Vacinne No Authorized for emergency use Yes; December 11, 2020 For use in … Yes; December 18, 2020 Individuals 16 years of age and older Individuals 18 years of age and older Sources: FDA. Retrieved from https://www.fda.gov/emergency-preparedness-and-response/coronavirus-disease-2019-covid-19/covid-19-vaccines Projected delivery Vaccine PfizerBioNTech COVID-19 Vaccine Moderna COVID-19 Vacinne Number of ordered doses 200 million for $3,9 billion (with the option to acquire up to 400 million additional doses) Initial order Projected delivery 100 million doses for $1.95 billion with the option to acquire up to 500 million additional doses (July 22, 2020) Source: https://www.pfizer.com/news/pressrelease/press-release-detail/pfizer-andbiontech-announce-agreement-usgovernment-600 200 million (with the option to acquire up to 300 million doses of the Moderna vaccine) Source: https://www.hhs.gov/coronavirus/explaining-operation-warp-speed/index.html Possible second order 100 million additional doses (December 23, 2020). Consistent with the original agreement the government will pay $1.95 billion for the additional doses Projected delivery Expects to deliver the full 200 million doses by July 31, 2021 70 million of the additional Source: doses by June https://www.pfizer.com/news/press30, 2021 release/press-release-detail/pfizer The remaining and-biontech-supply-us-100-million30 doses to be additional-doses delivered no later than July 31, 2021 Continued delivery through the end of June 2021 Cost-benefit analysis 1. Specify current and alternative policies; Vaccinate according to recommendation by Center for Disease Prevention and […] (baseline option) Vaccinate according to the principle of first come, first served Vaccinate according to risk category 2. Specify whose costs and benefits count; Costs: Development costs Costs of vaccines and materials (assumption: two doses to obtain protective immunity) Costs of administration Transport costs Benefits The product of mortality The value of statistical life The fraction that is lost on average due to Covid-19 deaths Assumptions: Look at current data and compare it with existing conditions, age, and so on Then assume that the trend continues Compare it across policies Scenarios: Three different scenarios: Enough supply to vaccinate 20%, 40% and 60% 3. Catalogue relevant impacts (∆𝑿); 4. Predict impacts over the time horizon of policies; 5. Monetize all impacts (multiply ∆𝑋 with shadow prices) and calculate benefits; 6. Discount benefits and costs to obtain present values; 7. Compute the present value of net benefits; 8. Perform sensitivity analysis; 9. Recommend.