Endocrine Ed –
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Control Ed's endocrine glands to regulate his blood sugar, fight or flight response,
sleepiness and more! You will learn about feedback loops (negative feedback) and will
need to apply this knowledge to new situations in this amusing animated experience!
Hormones and Feedback:
1.
2.
3.
4.
5.
Hormones are secreted by an _____endocrine__________________ gland.
They travel by which method? ______blood to target cells_______________.
__target cells______ have receptors for the hormones.
____homeostasis____________________ is like being in balance or a teeter totter.
Once homeostasis is achieved, the _____brain_____________ turns off production of
the hormone. This is called negative feedback.
Complete the diagram:
Pituitary  ______stops making________  ____stops having______ (effect)
Without feedback, what would happen to a person’s height? ___they would get
taller_________________
Questions:
1. How does a feedback loop work?
Pituitary gland stops making  Human growth hormone stops having  effect (growth)
^
^
|
|
-----------------------------------------------------------------------------------------------------------------Brain turns off
2. What would happen if negative feedback did not occur? The brain would keep producing the
hormone.
3. What is the role of the brain? To turn off the pituitary gland and to monitor the body
Adrenaline and Stress:
1. List several effects of adrenaline: increase heart rate, blood pressure, muscle strength,
breathing rate, etc.
2. Adrenaline gets the body ready for __action______________.
Game: control Ed’s adrenaline
What is one thing that will raise his adrenaline level? Being chased by a killer bee, tiger, or
hamster.
Quiz:
1. In which situation would adrenaline most likely be secreted by the adrenal glands? In
stressful situations
2. When sufficient adrenaline has been secreted, production stops. This is known as
___negative response_________________ feedback.
Melatonin and Sleep:
1. Melatonin production is high when it is ____dark__________.
2. It is secreted by the ___Pineal_______________ gland.
3. Do melatonin levels remain constant during the night? _______no_________
Blood Sugar Hormones:
1. What four areas are affected by insulin (they have insulin receptors)?
2. The brain, liver, cells, and muscle
3. Insulin causes cells to ____produce_________ sugar and therefore
_decrease____________ blood sugar levels.
4. Glucagon causes the ___liver__________ to release sugar and cause a
___increase________ in blood sugar levels.
Game: When you exercise, blood sugar levels ___drop_________ causing the release of
______glucagon____________ to bring those levels back to normal ranges.
Quiz:
Matching: hormones to their function
__A___ 1. Raises blood sugar
_D____ 2. Helps you sleep
__B___ 3. Increases muscle strength
__C___ 4. Lowers blood sugar
A. adrenaline
B. glucagon
C. Insulin
D. melatonin
5. Calcitonin lowers blood calcium adding that calcium to the ______blood.______.
6. The parathyroid __increases_________ blood calcium by taking the calcium from the
____bloodstream_______.
7. Once homeostasis is reached, hormone release will be ______stopped____________.
8. If blood sugar levels are too high, ___Aldosterone_________ is released.
9. If blood sugar levels are too low, ___Angiotensin___________ is released.
10. Antidiuretics (ADH) help the body retain water by affecting the _____________ (organ).
Red are my answers
1. Where are natural corticosteroids produced?
thymus
adrenal glands
pituitary
pons
2. What is the best known corticosteroid?
prednisone
colitis
testosterone
aspirin
3. In general, corticosteroids work by:
elevating the blood pressure
reducing swelling
improving circulation
suppressing the immune system
4. Corticosteroids are used to treat what ailment(s)?
asthma
arthritis
psoriasis
all of these
5. Long term use of a steroid inhaler by children can cause what side effect?
delayed sexual development
mood swings
slowed growth
weight gain
6. More serious side effects occur when steroids are:
taken for long periods
taken in children
injected
prescribed by doctors
7. Why is it necessary to slowly stop the use of steroids, rather than abruptly
stop usage?
the heart could suffer damage
the adrenal glands need time to start producing natural hormones
seizures can occur from withdrawal
8. What is the theme of this article?
Steroids can help treat illnesses, but there are also risks
Steroids should only be taken with a doctor’s supervision
Steroids are dangerous and should not be legal
9. Based on the context of the sentence in the last paragraph, what do you
think the definition of "abates" is?
becomes worse
stops working
goes away
10. Based on the context of the article, what do you think an "autoimmune
disease" is?
when your immune system reacts to things it should not
an ailment that is easily transmitted from one person to another
a problem caused by the extended use of steroids