Autonomic Nervous system Medical Physiology 2nd Module 2020 Items to be discussed • Introduction. • Integration of Sympathetic and parasympathetic functions • Sympathetic and Parasympathetic tone. • Control of autonomic nervous system. Introduction Integration of Sympathetic and parasympathetic functions Sympathetic and Parasympathetic tone • Definition: The sympathetic and parasympathetic systems are continually active, and the basal rates of activity are known, respectively, as sympathetic tone and parasympathetic tone. • Value: it allows a single nervous system both to increase and to decrease the activity of a stimulated organ. Sympathetic tone • Example: The sympathetic tone keep most of blood vessels partially constricted and this maintains ABP. • Loss of sympathetic tone → drop of blood pressure and shock. Parasympathetic tone • Example: The parasympathetic tone 1. Maintains smooth muscle tone of intestine 2. keep resting HR 70- 80 bpm to ↓ inherited rhythm of SAN (vagal tone) • Cut of parasympathetic vagus nerve to the heart→ the heart beats by its intrinsic rate (100 bpm) Control of the ANS • (A)Reflex control of autonomic functions. • (B)Higher control of autonomic function (a)Reflex control of autonomic function. 1. Spinal autonomic reflex: Produce responses by stimulating the spinal autonomic centers (LHCs) e.g.(The micturition and defecation reflexes). 2. Brain stem autonomic reflexes: Produce responses by stimulating the cranial parasympathetic centers in brain stem, e.g: I.Reflex salivary, gastric and pancreatic secretion. II.Reflex pupilloconstriction. (B)Higher control of autonomic functions • (1)The reticular formation. • (2)The hypothalamus. • (3)The cerebral cortex. Thank You