BIO 202 Exam 4 Prep Urinary System: 1) Draw a flow diagram that represents the steps associated with the renin angiotensin aldosterone system. Recommended starting point: Juxtaglomerular apparatus (GFR = GLOMERULAR FILTRATION RATE) 3 structures that make up juxtaglomerular apparatus - macula densa - extraglomerular cells - juxtaglomerular cells Low GFR (sensed by macula dense cells and JGC’s) >> JGC cells release renin >> renin is an enzyme that converts angiotensinogen to angiotensin I >> ACE converts >> angiotensin II angiotensin II (vasoactive form) >> vasoconstriction of efferent arterial (leaving) = less blood leaves glomerulus >> fluids refiltered out of glomerulus into bowman’s space (leads to PCT, loop of Henle, etc.) >>> GFR INCREASES 2) Describe the mechanism of action of Antidiuretic Hormone (ADH), be sure to specifically mention what is occurring to the tubular cells of the nephron. ADH secreted from Neurohypophysis >> increases the reabsorption of water via aquaporins in membrane of tubular cells in nephron (at level of collecting duct) 3) In your own words describe the how the nephron carries out the function of the kidney: filtration and absorption. Be sure to mention the primary structures involved and how they contribute to that function glomerulus = filtration filtration membrane 1. pores 2. basal layer/basement membrane 3. filtration slits - large component stay in blood stream (exit via efferent arteriole) - small components are filtered into Bowman’s space >> PCT capillary / loop of henle absorption 1. H2O is absorbed on descending limb 2. solutes absorbed on the ascending limb * H2O follows solutes* - countercurrent flow between capillary network and loop of henle - solutes leave and enter blood stream and draws H2O out - fluid that is reabsorbed into the blood stream will eventually lead to the renal vein Reproductive Systems: 1) Explain the potential barriers that sperm must overcome to reach oocyte within the fallopian tube. slide 2 of pt. 4 2) Suppose fertilization and implantation did not occur, what happens to the corpus luteum and endometrium. 3) In your own words describe the menstrual cycle. Be sure to mention all five hormones (HCG = 5th), where they are secreted from, and what their roles are. Also, make sure you are linking the changes of the ovarian cycle and how they are contributing to changes of the uterine cycle.