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BIO 151 exam 2 study guide

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BIO 151
Understand the processes of DNA replication, transcription, and translation. Know the main molecules
involved and what is being produced in each.
Understand the concept of complimentary base pairing in DNA and RNA.
Be able to determine how a change in DNA nucleotide sequence will affect a protein sequence.
Understand the basic types of DNA mutation.
Know the structure of a DNA molecule. Its shape, what it is made of, and understand what it does to
replicate.
What is the difference between ‘leading’ and ‘lagging’ strands of DNA?
How are the 2 strands replicated differently, why?
How is RNA different from DNA? How is RNA made complementary to DNA sequence?
What are ‘exons’ and ‘introns’ in DNA and RNA?
What does ‘semiconservative’ replication mean?
Understand the central dogma: DNA to RNA to protein and how this happens.
Given a sequence of DNA can you predict the sequence of RNA created? How about protein (given a codon
table)?
Know how to use a codon table and what a codon is.
Why is Edwin Chargaff famous?
Which enzyme makes DNA during replication? RNA during transcription?
Where would you find an ‘anti-codon’? Why is it important for translation?
Define the process of transcription briefly.
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