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Description
What is fentanyl?
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Fentanyl is an opioid medication. An opioid is sometimes called a narcotic.
Fentanyl is used as part of anesthesia to help prevent pain after surgery or other medical
procedure.
Fentanyl may also be used for purposes not listed in this medication guide.
Important information
You should not receive this medicine if you are allergic to fentanyl or other narcotic pain
medicines.
It is very important that you are monitored closely by your doctor when receiving fentanyl
injection. This will allow your doctor to determine whether it is working properly and if you should
continue to receive treatment.
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Check with your doctor right away if you or your child have bluish lips or skin; chest pain;
difficulty with breathing; a fast, pounding or irregular heartbeat or pulse; shortness of breath; or
muscle stiffness after receiving fentanyl.
MISUSE OF NARCOTIC MEDICATION CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or
other person using the medicine without a prescription.
Before taking this medicine
You should not receive this medicine if you are allergic to fentanyl or other narcotic pain
medicines.
Some medicines can interact with fentanyl and cause a serious condition called serotonin syndrome.
Be sure your doctor knows if you also take medicine for depression, mental illness, Parkinson’s
disease, migraine headaches, serious infections, or prevention of nausea and vomiting. Ask your
doctor before making any changes in how or when you take your medications.
To make sure fentanyl is safe for you, tell your doctor if you have:
any type of breathing problem or lung disease;
history of head injury or brain tumor;
liver or kidney disease;
slow heartbeats; or
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if you have used an MAO inhibitor (isocarboxazid, linezolid, methylene blue injection,
phenelzine, rasagiline, selegiline, tranylcypromine) in the past 14 days.
It is not known whether fentanyl will harm an unborn baby. If you use fentanyl while you are
pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal
symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need
medical treatment for several weeks. Tell your doctor if you are pregnant or plan to become
pregnant.
It is not known whether fentanyl passes into breast milk or if it could harm a nursing baby. Tell
your doctor if you are breast-feeding a baby.
How is fentanyl injection given?
Fentanyl is injected into a muscle, or into a vein through an IV. A healthcare provider will give
you this injection as part of the anesthesia given for your surgery or medical procedure.
Your breathing, blood pressure, oxygen levels, and other vital signs will be watched closely while
you are receiving fentanyl.
You may be given other pain medications to use after your fentanyl treatment is discontinued.
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What happens if I miss a dose?
Since fentanyl is given as needed by a healthcare professional for only a short time, you are not
likely to be on a dosing schedule.
What happens if I overdose?
Since this medication is given by a healthcare professional in a medical setting, an overdose is
unlikely to occur.
What should I avoid after receiving fentanyl?
Fentanyl can cause side effects that may impair your thinking or reactions. You should not plan on
driving or doing anything that requires you to be awake and alert right after you are treated with
this medication. Dizziness or severe drowsiness can cause falls or other accidents.
Follow your doctor’s instructions about any other restrictions on food, beverages, or activity.
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Get emergency medical help if you have any signs of an allergic reaction to fentanyl: hives;
difficult breathing; swelling of your face, lips, tongue, or throat.
Your caregivers will watch for any side effects you have, which may clear up within minutes after
stopping the fentanyl infusion or decreasing the dose:
weak or shallow breathing;
fast or slow heart rate;
stiff muscles; or
severe weakness, feeling light-headed or fainting.
Common fentanyl side effects may include:
slowed breathing;
slow heart rate;
muscle stiffness;
dizziness, vision problems;
nausea, vomiting;
itching, sweating; or
high blood pressure (confusion, anxiety, pounding in your neck or ears).
This is not a complete list of side effects and others may occur. Call your doctor for medical
advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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What other drugs will a ect fentanyl?
Some medicines can cause unwanted or dangerous effects when used with fentanyl. Tell your doctor
about all medicines you use now, and any medicine you start or stop using.
For a short time after you receive fentanyl, using other medicines that make you sleepy or slow your
breathing can cause dangerous or life-threatening side effects. Ask your doctor before taking a
sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or
seizures.
Other drugs may interact with fentanyl, including prescription and over-the-counter medicines,
vitamins, and herbal products. Tell each of your health care providers about all medicines you use
now and any medicine you start or stop using.
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