Lesson objectives • • • • • • • Students should be able to: (a) define a drug as any externally administered substance that modifies or affects chemical reactions in the body (b) describe the medicinal use of antibiotics for the treatment of bacterial infection (c) describe the effects of the abuse of heroin: a powerful depressant, problems of addiction, severe withdrawal symptoms and associated problems such as crime and infection, e.g. AIDS (d) describe the effects of excessive consumption of alcohol: reduced self-control, depressant, damage to liver and social implications (e) describe the effects of tobacco smoke and its major toxic components (nicotine, tar and carbon monoxide) on health: strong association with bronchitis, emphysema, lung cancer and heart disease, and the association between smoking during pregnancy and reduced birth weight of the baby (f) recognize the fact that many people regard smoking as no longer socially acceptable. A DRUG IS ANY SUBSTANCE OTHER THAN FOOD WHICH CHANGES THE WAY THE BODY OR MIND FUNCTIONS. Broadly classified as Pharmaceutical Drug • It is also called a medication or medicine, is a chemical substance used to treat, cure, prevent, or diagnose a disease or to promote wellbeing. Psychoactive Drug • It is a chemical substances that affect the function of the central nervous system, altering perception, mood or consciousness MEDICINAL DRUGS: ANTIBIOTICS: Antibiotics are chemicals that are widely used to treat many infectious diseases caused by microorganisms. Antibiotics do not harm viruses. There are 4 main types of antibiotics: Penicillins: Fungus penicillium, narrow-spectrum antibiotics. Cephalosporins: Mould cephalosporium. They are useful against bacteria which have developed resistance to penicillin. Tetracyclines: Bacterium Streptomyces , broadspectrum antibiotics. Erythromycins: Bacterium actinomycete , often used for people that have an allergy to penicillins Anaesthetics and Analgesics Anaesthetics: Drugs that make the body unable to feel pain. Analgesics: Drugs which relieves pain and reduces fever. WORKING OF ANTIBIOTICS: Penicillin, for example, prevents the bacteria from making essential components of the cell wall which makes it easier for the body’s immune system to destroy it. Tetracyclines, on the other hand, damage the proteinproducing machinery inside the cytoplasm of the bacterium, thereby preventing it from dividing. This inhibits the growth of the bacterium. Diseases treated with antibiotics: Pneumonia , Syphilis, Infections etc TYPES OF PSCHOACTIVE DRUGS • • • • Stimulants Depressants Hallucinogens Opiates Types of PSYCHOACTIC drugs Stimulants (uppers) – Speed up the brain and central nervous system. Examples are caffeine (coffee, tea) nicotine (cigarettes), amphetamines, cocaine and diet pills. Types of drugs Depressants (downers) – Slow down the brain and central nervous system. Examples are alcohol, beer, wine, tranquilizers, sleeping pills. Types of drugs • OPIATES (PAIN KILLER) • Used to reduce pain • Examples: Heroin and morphine. Types of drugs Hallucinogens – These drugs alter the user’s state of consciousness. (Distort auditory and visual sensations) Examples are LSD, ecstasy, magic mushrooms, marijuana. ALCOHOL • Alcohol goes directly from your digestive system into your blood and within minutes spreads to entire body, including brain • It spreads evenly throughout bodyexcept brain which gets the highest concentration because it gets more blood than any other part of body • More blood equals more alcohol • Intoxication (drunkenness) starts in the brain 1. Mouth 2. Stomach 3. Small Intestine 4. Bloodstream 5. Liver 6. Brain Alcohol Physical Effects • Co-ordination is impaired, clumsiness, slower reflexes • High blood pressure, damage to the heart • Liver damage • If drinking when pregnant, FASD • Life threatening when mixed with other drugs Mental and Emotional • Behave in ways that you normally wouldn’t • Increase in aggressive and violent behaviour • Problems with school and learning ALCOHOL and the LIVER • The liver removes poisons – include alcohol from the body • People who drink regularly can have serious liver damage and may even get liver cancer • If the liver is damaged badly enough, it can stop working, causing the person to die. FACTS ABOUT SMOKING: Cigarette smoke contains more than 4000 chemicals; many of which are harmful to the body. Following chemicals in cigarette are linked to health problems. NICOTINE NICOTINE • Most addictive drug • Causes more long term health problems than any other drug • Adults are smoking less, younger people under 18 smoke more • When someone stops smoking they have: strong cravings irritability (everything gets on nerves) thoughts of it-can’t stop thinking about it NICOTINE What it does to your body, brain and behavior • • • • • depression lung cancer lung diseases heart disease skin becomes thinner and wrinkled CARBON MONOXIDE: Carbon monoxide reduces the efficiency of the red blood cells to transport oxygen It also increases the rate at which fatty substances are deposited on the inner walls of the arteries, causing their lumen to become narrower. This increases the risk of atherosclerosis. It damages the lining of blood vessels, thus increasing the tendency of blood to clot and so block the blood vessels TAR: This is a brown, sticky substance that accumulates in the lungs during smoking. It contains many cancer causing (carcinogenic) chemicals. Normally, cell division occurs continuously in the lungs to replace the membrane of the air sacs. Tar induces these cells to divide at an abnormal rate. Such uncontrolled multiplication of cells results in outgrowths or lumps of tissues (cancers). These block off the air sacs, reducing the efficiency for gaseous exchange. Tar paralyses the cilia lining the air passages. This prevents the cilia from removing the dust particles from the lungs and the trachea. IRRITANTS (e.g hydrogen cyanide, acrolein, formaldehyde) Paralyses cilia lining the air passages. Increases risks of chronic bronchitis and emphysema HEROIN • Processed from morphine – obtained from opium poppy • “downer” affects brain’s pleasure systems – interferes with brains ability to feel pain HEROIN • white to dark brown powder or tar-like substance • is cut with other drugs or substances (sugar, starch, powdered milk) • abusers don’t know actual strength of drug or true contents = high chance of overdose or death • sharing needles and equipment cause other diseases and problems for users HEROIN • leads to flushing of skin, dry mouth, collapsed veins, liver disease • additives don’t dissolve leading to clogs in blood vessels that lead to lungs, liver, kidney or brain • tolerance develops with regular use – user needs more heroin to achieve same intensity Substance abuse and society What are the effects of substance abuse on society? • Spread of diseases such as HIV/AIDS and Hepatitis C through sharing needles. Substance abuse and society Effects on unborn children or other complications from drug use EFFECTS OF DRUG USE ON CHILD • • • • • • Miscarriages Premature birth Low birth weight Birth defects Developmental problems A baby’s health problems, if caused by a drug will continue to grow as the child grows. Substance abuse and society CRIME • • • • • drug possession drug use drug manufacturing robbery motor vehicle theft Conclusion: All medicines are drugs but not all drugs are medicines Drug abuse is habitual use of illegal drugs which can lead to serious consequences