UNIT - III :GENETICS SR.BOTANY EAMCET - VOL - I Chapter 9 Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION PRINCIPLES OF INHERITANCE AND VARIATION P Generation Red RR Meiosis I - anaphase Meiosis II - anaphase Meiosis II - anaphase Germ cells Germ cells White rr × Gametes Meiosis I - anaphase r R F1 generation Pink Rr Gametes ½ R ½ r Eggs ½ R ½ r F2 generation ½ R Sperms RR ½ r Rr Rr rr Independent assortment of chromosomes Introduction.... Gregor Johann Mendel an Austrian monk, discovered the basic principles of heredity He conducted experiments on the Pea plant In 1850 Mendel began to research the transmission of Hereditary traits in plant hybrids. He published the results of his studies under the title ‘Experiments on plant Hybrids’ In 1900, Hugo de Vries, Karl correns and Tschermak these three workers rediscovered Mendel’s work independently After rediscovery of Mendel’s work, he is rightly known as Father of Genetics. NARAYANAGROUP 99 UNIT - III :GENETICS Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION SR.BOTANY EAMCET - VOL - I CHAPTER AT A GLANCE INTRODUCTION PRACTICE TEST - I 9.1 MENDEL’S EXPERIMENTS GENETIC TERMINOLOGY MENDEL’S EXPERIMENTAL PLANT PRACTICE TEST - II 9.2 INHERITANCE OF ONE GENE (MONOHYBRID CROSS) PRACTICE TEST - III 9.3 DEVIATIONS FROM MENDELIAN CONCEPT OF DOMINANCE PRACTICE TEST - IV 9.4 INHERITANCE OF TWO GENES (DIHYBRID CROSS) PRACTICE TEST - V 9.5 CHROMOSOMAL THEORY OF INHERITANCE PRACTICE TEST - VI 9.6 LINKAGE AND RECOMBINATION 9.7 MUTATIONS PRACTICE TEST - VII QUESTION BANK EXERCISE - I CHECK YOUR MEMORY EXERCISE- II SHARPEN YOUR REFLEXES EXERCISE-III THINK TWICE BEFORE YOU CHOOSE EXERCISE - IV SIMPLE MATCHING EXERCISE - V EXERCISE - VI TRUE OR FALSE EXERCISE - VII PREVIOUS MEDICAL ENTRANCE MULTIPLE MATCHING QUESTIONS 100 NARAYANAGROUP UNIT - III :GENETICS SR.BOTANY EAMCET - VOL - I Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION SYNOPSIS PRACTICE TEST-I INTRODUCTION Genetics is the science deals with the inheritance as well as the variation of characters from parents to offspring. Inheritance is the process by which characters are passed from parents to offspring. The entire body of molecular biology was a consequent development with major contributions from Watson, Crick, Nirenberg, Khorana, Kornbergs (father and son), Benzer, Monod, Brenner, etc. Mendel factors (now a days genes), those controls inheritance patterns represent the genetic basis of inheritance, understanding the structure of genetic material and the structural basis of genotype and phenotypic conversions. Gregor Johann Mendel is an Austrian monk, discovered the basic principles of heredity through experiments on the pea plant. Around 1850, Mendel began to research the transmission of hereditary traits in plant hybrids. He published the results of his studies under the title “Experiments on Plant Hybrids”. The observations he made while growing peas in his monastery’s garden became the foundation of modern genetics and the study of heredity. “Like begets like” and “as you show so you reap” because an organism gives birth to organisms similar to it only. Eg: An elephant always gives birth to baby elephant and mango seed forms only plant producing mangoes. Children in a family show similarities to their parents because certain characters are passed from the parents to the offspring or progeny during sexual reproduction. This is called heredity. However siblings are not identical to parents and they show differences which are called variations. Between 8000 - 1000 BC humans recognised that causes of variations are in sexual reproduction. They used the variations present in wild populations for improvement of plants and animals by selective breeding. Eg: Sahiwal cows in Punjab. Ongole bulls in Andhra Pradesh. Though ancestors know about heredity and variation yet they had no idea of scientific basis of heredity. NARAYANAGROUP 1. Sexual reproduction brings about 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 1) Polyploidy 2) Aneuploidy 3) Euploidy 4) Genetic recombination Genetics deals with 1) Heredity and Variations 2) Mutations 3) Variations 4) Mendel’s laws Laws of inheritance are the base to the scientific explanation of 1) Heredity 2) Variations 3) Eugenics 4) 1 and 2 During sexual reproduction, characters are transmitted through 1) Vegetative cells 2) Gametes 3) Propagules 4) Clones The unit of heredity is 1) Chromosome 2) DNA and RNA molecules 3) Nucleus 4) Gene The most popularised person considered in the field of genetics is 1) Engler 2) Schwann 3) Johanssen 4) Mendel Example of an animal developed by artificial selection and domestication in north India 1) Drosophila 2) Mule 3) Sahiwal cows 4) Ongole bulls The entire body of molecular biology was a consequent development with major contributions from 1) Benzer 2) Brenner 3) Nirenberg 4) 1,2 and 3 The process of transmission of parental characters to the offspring is 1) Variations 2) Inheritance 3) Mendelism 4) Hybridization “Characteral resemblances among same progeny and also with their parents is possible”. The reason is the difference in characters among same progeny is due to 1) Variations 2) Gene manipulation 3) Cloning of genes 4) Lack of alleles Who discovered the basic principles of heredity through experiments on the pea plant. 1) Mendel 2) Morgan 3) Hugo de Vries 4) Correns Mendel published the results of his studies under the title 1) Experiments on animals 2) Enquiry into plants 3) Historia plantarum 4) Experiments on plant hybrids. 101 UNIT - III :GENETICS SR.BOTANY EAMCET - VOL - I Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION 13. Between 8000 - 1000 BC humans recognised that causes of variations are found in. 1) Asexual reproduction 2)Vegetative reproduction 3) Fission 4) Sexual reproduction 14. Mendel conducted experiments on a plant belongs to family 1) Solanaceae 2) Fabaceae 3) Liliaceae 4) Cucurbitaceae 15. Example of an animal, developed by artificial selection and domestication in AP 1) Sahiwal cows 2) Mules 3) Ongole bulls 4) Drosophila Gregor Johann Mendel Mendel was born on 22 July 1822 in Austria. In 1856–57, he started his historical experiments of heredity on garden pea plant [Pisum sativum] and continued upto 1863 for 7 years. The results of his experiments were published in the science Journal in 1866 entitled “Experiments on plant Hybrids”. His experiments were ingenious. He is the first person to use statistical analysis and mathematical logic for interpreting the results. The use of larger sample size brought credibility to the data collected. He prepared the basic frame work of rules governing inheritance as the characters in pea are maintained as opposite traits. By using true breeding line/pure line he conducted artificial cross pollination experiments. Genetic Terminology Gene: A gene is the unit of DNA responsible for the appearance and inheritance of a character in the present day literature and Mendel called it as element or factor. Allele is one of the two members of a gene pair. Eg: T or t Allelomorphs or Alleles are a pair of genes that control the two alternatives of the same character. Gene Locus: The position of a gene on chromosome is called locus. The alleles of a gene are present at the same gene locus on homologous chromosome. Heterozygous: The organism in which both the genes of a character are unidentical is said to be heterozygous. Such organisms do not breed true on self fertilization eg. Tt. Homozygous: The organism in which both the genes of a character are identical is said to be homozygous or genetically pure for that character. e.g TT or tt. Dominant and recessive gene: A heterozygote possesses two contrasting genes or alleles but 102 only one of the two is able to express itself, while the other remains hidden. The gene which is expressed in F1 hybrid is known as dominant gene. The gene which is not expressed in F1 hybrid is known as recessive gene. Genotype: The genetic constitution of an organism is called genotype. OR The sum total of genes inherited from both the parents irrespective of whether they are expressed or not is called genotype (Johanssen). Phenotype: The physical appearance of an individual is called phenotype. purelines: The homozygous organisms which produce offspring of only one type are called purelines. (or) Progeny produced from a single homozygous parent by repeated self pollination. Genome: Total set of genes in the haploid set of chromosomes is called genome. 9.1 Mendel’s Experiments Mendel selected common garden pea (Pisum sativum) for his experiments, because the plant shows the presence of several contrasting traits, hence it was useful in his experiments. He selected fourteen true breeding pea plant varieties which were similar except for one character with contrasting traits. Mendel conducted artificial pollination/ cross pollination experiments using several true breeding pure lines (A truebreeding line is one that, having undergone continuous self pollination showing the stable trait inheritance and expression for several generations). Mendel selected 14 true breeding pea plant varieties. A true breeding line is one that having undergone continuous self pollination, shows the stable trait inheritance and expression for several generations. Table : Characters of Garden Pea picked up by Mendel Characters Stem Height Flower Colour Flower position Pod shape Pod colour Seed shape Seed colour Dominant trait Recessive trait Tall (T) Violet (W) Axial (A) Dwarf (t) White (w) Terminal (a) Inflated (I) Green (G) Round (R) Constricted (i) Yellow (g) Yellow (Y) Wrinkled (r) Green (y) NARAYANAGROUP UNIT - III :GENETICS SR.BOTANY EAMCET - VOL - I 16 17 18. 19. 20. 21. 22. 23. 24. Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION 3) alternative forms of a gene Advantages of selecting garden pea plant by Mendel 4) alternative forms of a character for his hybridization experiments are 25. Mendel conducted hybridisation experiments on 1.It is an annual plant that has well defined 1) Pigeon Pea 2) Garden Pea characters. 3) Wild Pea 4) Sweet Pea 2. It can be grown and crossed easily. 3. It has bisexual flowers containing both female and 26. Sexuality of the flowers of pea plant 1) Staminate flower 2) Bisexual flower male sex organs. 3) Pistillate flower 4) 1 and 3 4. It can be self fertilized conveniently. 5. It has a short life cycle and produces large no of 27. Offsprings produced from a cross made between two pure lines is called offsprings. 1) hybrids 2) mutants 3) P generation 4) F2 generation PRACTICE TEST-II 28. Which one of the following pairs is not of a contrasting character Genotype is 1) Tall and dwarf 2) Axial and terminal 1) Genetic composition of species 3) Green and yellow 4) Round and yellow 2) Genetic composition of plastids 29. Inbreeding is also known as 3) Genetic composition of germ cells 1) cross fertilization 2) self fertilization 4) Genetic composition of an individual 3) cross pollination 4) vegetative fertilization Alleles of a gene are found on 30. In Pisum sativum, the dwarfness of plant is a 1) non homologous chromosomes .... character. 2) homologous chromosomes 1) dominant 2) recessive 3) same chromosome 4) any chromosomes 3) co-dominant 4) incomplete dominant The external appearance of an individual 31. Mendel selected pea plant for his experiments 1) genotype 2) phenotype because it has 3) recessive 4) dominant 1) short life cycle Organism with two copies of the same allele is 2) large number of offsprings 1) homozygous for that trait 3) self fertilized conveniently 4) 1, 2 and 3 2) homologous for the allele 32. Which of the following characters is not 3) heterozygous for that trait considered in pea plant by Mendel 4) heterologous for the allele 1) Pod shape 2) Leaf shape The F1 generation is 3) Plant height 4) Pod colour 1) homozygous 2) heterozygous 33. Genes of today’s world were Mendel’s 3) recessive trait 4) dominant for both the alleles 1) genes only 2) factors On inbreeding, the homozygous parents will 3) chromosomes 4) plasmid produce 34. Which of the following principle was not 1) all similar offsprings proposed by Mendel. 2) 25% similar and 75% dissimilar 1) segregation 2) blending inheritance 3) 75% similar and 25% dissimilar 3) dominance 4) independent assortment 4) 50% similar and 50% dissimilar 35. In Pisum sativum, the dominant character of Organisms phenotypically similar but seed is genotypically different are due to 1) violet 2) round 1) heterozygosity 2) monozygosity 3) wrinkled 4) green 3) multizygosity 4) homozygosity 36. Number of vegetative characters considered Allele is called by Mendel in pea plant 1) a pair of chromosomes 1) seven 2) three 2) a pair of sex chromosomes 3) fourteen 4) one 3) a pair of gene of contrasting character 9.2 Inheritance of one Gene 4) a pair of vegetative chromosomes (or) Monohybrid Cross An allelomorph is The cross made between two parents differing in 1) total number of genes for a trait one contrasting trait is called monohybrid cross. 2) total number of genes on chromosome NARAYANAGROUP 103 UNIT - III :GENETICS SR.BOTANY EAMCET - VOL - I Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION Mendel crossed pure tall and dwarf pea plants to F2 Genotypic ratio 1 : 2 : 1. study the inheritance of one gene or one factor. F2 parental combinations to recombination ratio 1 : 1. Crossing or hybridization involves selection of parents, emasculation of flowers of female parent, F2 dwarf plants are homozygous because they form artificial pollination, fertilization. 100% dwarf in F3 , F4 or onward generation. He found only tall plants and no dwarf plants in F1 or first filial generation. Only one parental trait is Among F2 tall plants out of three one plant breeds true and the remaining two form both tall and dwarf expressed. The same occurred in the case of all in next generation on selfing. Hence among tall 1/3 contrasting characters. are homozygous 2/3 are heterozygous. The character expressed in F1 is called dominant The binomial expression of monohybrid genotypic and unexpressed is called recessive. Selfing of F1 ratioof homozygous tall, heterozygous tall and 1 1 1 2 3 1 homozygous dwarf is : : ax by . plants produced tall and dwarf in and 4 2 4 4 4 proportions. No plant was in between tall and dwarf The expression is expanded as given below 1/ 4TT 1/ 2Tt 1/ 4tt and so there was no blending of traits in either F1 Pure homozygous dwarf pea plant or F2 generations. tall pea plant tt P1Parental gen. TT Mendel proposed that characters are governed by factors or elements or units now called genes. They t Gametes T occur in different forms and denoted by alphabetical symbols. They occur in pairs because one is F gen. contributed by male and another by female during Tt (1st filial gen.) Heterozygous tall or hybrid tall fertilization. (Monohybrid) Selfing Different forms of the same gene are called alleles. Presence of identical alleles of same trait is called homozygous and dissimilar alleles is called t T heterozygous. TT Tt T Pure or Hybrid or All F1 progeny of pure tall and dwarf is Homozygous tall Heterozygous tall F gen. (2nd filial gen.) Tt tt t heterozygous. The cross between TT and tt is called Hybrid tall Dwarf monohybrid cross. In heterozygous condition (Tt) the phenotype is that 9.2.1(a) Back cross and Test cross: Back cross: It is a cross between F1 individual of dominant allele. and with either one of its parents. In a back Pure tall and dwarf plants genotypes are TT and tt respectively. As one allele is transmitted to a gamete, cross with dominant parent, the phenotypic parent with TT produces all gametes carrying ratio of tall and dwarf plants is 1:0 and the Results of selfing can be represented by Checkar board or Punnet-square 1 allele only. Parent with tt produces all gametes carrying allele only.. The hybrids are phenotypically tall but have factors governing contrasting traits. Hence they are Tt or heterozygous. F1 hybrid produce gametes carrying and 2 genotypic ratio of tall and dwarf is1:1. Tall Tall TT T X T T t T T . TT Parent T t gametes t Tt The F2 is raised by selfing F1 . In F2 all possible phenotypes and genotypes probabilities are T TT Tt calculated by punnettt square developed by Reginald C Punnett. Test cross: The cross made between F1 with F1 phenotypic and genotypic ratio of tall to dwarf 1 : 0. recessive parent is called test cross. F2 phenotypic ratio 3 : 1. 104 NARAYANAGROUP UNIT - III :GENETICS SR.BOTANY EAMCET - VOL - I Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION Monohybrid test cross ratio 1 : 1. The law of segregation postulates that alleles in Test cross is conducted to find out the genotype heterozygous condition co exist and do not blend of unknown parent. or mix and they separate and enter into different When tested plant is homozygous the ratio of gametes during meiosis. dominant phenotype to recessive phenotype is 1 : 0. Segregation of genes is a universal phenomenon Eg: Violet White flowered plants of Pea = All in all organisms reproducing by normal sexual Violet. method. When tested plant is heterozygous the ratio of dominant phenotype to recessive phenotype is 1 : 1. Eg : Violet White = 50% Violet : 50% white Homozygous recessive Homozygous recessive ww w ww w w ? W Ww Ww if if WW Ww W Ww Ww w W Ww Ww Result w ww All flowers are violet Interpretation Unknown flower is homozygous (WW) ww Half of the flowers are violet and half of the flowers are white Unknown flower is heterozygous (Ww) Diagrammatic representation of a test cross. Monohybrid cross and its reciprocal cross gives same results, based on it Mendel proposed law of dominance and segregation. 9.2.1(b) Law of Dominance : (i) Characters are controlled by discrete units called factors. (ii) Factors occur in pairs. (iii) In a dissimilar pair of factors pertaining to a character one member of the pair dominates (dominant) the other (recessive). The law of dominance is used to explain the expression of only one of the parental characters in a monohybrid cross in the F1 and the expression of both in the F2 . It also explains the proportion of 3 : 1 obtained at the F2 . When dissimilar alleles of same trait are present (heterozygous) one allele has phenotypic expression is called dominant. This is called law of dominance. 9.2.2 Law of segregation or Law of purity of gametes Mendel’s Law of segregation states that “the two alleles of a gene when present together in a heterozygous state, do not fuse or blend in any way, but remain distinct and segregate during meiosis or in the formation of gametes so that each meiotic product or gamete will carry only one of them”. This law is based on the fact that the alleles do not show any blending and that both the characters are recovered as such in the F2 generation though one of these is not seen at the F1 stage. NARAYANAGROUP 37. A pure tall Pea plant is crossed with pure dwarf Pea plant. The progeny is self pollinated. The ratio of true breeding tall Pea plants to true breeding dwarf Pea plants shall be 1) 2 : 1 2) 1 : 1 3) 3 : 1 4) 1:2 38. In a cross 45 tall and 14 dwarf plants were obtained, genotype of parents was 1) TT × TT 2) TT × Tt 3) Tt × Tt 4) TT × tt 39 The offspring of a cross between two individuals differing in at least one set of characters is called 1) polyploid 2) mutant 3) hybrid 4) variant 40. F1 hybrids contain 1) two different genes of a contrasting pair of characters 2) single gene of only one character 3) two genes of same character 4) single gene for all characters 41 What will be the genetic constitution of the offspring of a cross of individuals heterozygous (Zz) for an allele? 1) All ZZ 2) All zz 3) 1/2 ZZ : 1/2 zz 4) 1/4 ZZ : 1/2 Zz : 1/4 zz 42. An offspring of two homozygous parents differing from one another by alleles at only one gene locus is 1) back cross 2) monohybrid 3) dihybrid 4) trihybrid 43. If F1 is selfed for red colour, the genotypic ratio of the offsprings would be 1) 1 : 2 : 1 2) 3 : 1 3) 1 : 1 4) 9 : 7 44. Law of dominance and recessiveness was the result of 1) Back cross 2) Incomplete dominance 3) Dihybrid cross 4) Monohybrid cross 45. In reciprocal Mendelian crosses, the ratio of the offsprings will be 1) similar in phenotypic ratio 2) similar in genotypic ratio 3) both (1) and (2) 4) different in phenotypic ratio 46. Cross between hybrid and its parent is 1) Back cross 2) Reciprocal cross 3) Monohybrid cross 4) Dihybrid cross 105 UNIT - III :GENETICS SR.BOTANY EAMCET - VOL - I Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION 47. Heterozygous tall (Tt) and dwarf (tt) Pea plants are crossed. The ratio in the offspring shall be 1) All tall 2) All dwarf 3) 3 tall : 1 dwarf 4) 1 tall : 1 dwarf 48. tt crossed with Tt. What will be characteristic of offspring 1) 75% recessive 2) 50% recessive 3) 25% recessive 4) All dominant 49. Test cross is a cross between 1) Hybrid X Dominant parent 2) Hybrid X Recessive parent 3) Hybrid X Hybrid 4) Recessive & recessive 50. What is the process of crossing a recessive phenotype with its own hybrid called 1) Back cross 2) Test cross 3) Reciprocal cross 4) Out cross 51. In which position female gametes are written on Punnett's checker board 1) Outside the board on upper side 2) Outside the board on left side 3) Outside the board on right side 4) Outside the board any where 52. Law of dominance is proved by 1) Back cross 2) Incomplete dominance 3) Monohybrid cross 4) Dihybrid cross 53. The possibilities of genotype combination in F2 generation can be determined by 1) Punnett's checker board method 2) Forked line method 3) Multiplying the types of gametes 4) 1, 2 and 3 54. In which position male gametes are written on Punnett's checker board 1) Outside the board on upper side 2) Outside the board on right side 3) Outside the board on left side 4) Outside the board any where 55. The characters that appear in the first generation of pea plant are called 1) recessive characters 2) dominant characters 3) both recessive and blended characters 4) incomplete dominant 56. The appearance of a hidden character in some offsprings in F2 generation obeys the law of 1) purity of gametes 2) dominance 3) independent assortment 4) co-dominance 57. When one member of a pair of allelic genes express itself as a whole, it is a case of 1) dominance 2) co-dominance 3) incomplete dominance 4) pleomorphism 58. Mendel’s law of segregation is applicable during 1) formation of gametes 2) fusion of gametes 3) formation of zygote 4) formation of PEN 9.3-Deviations from Mendelian Concept of Dominance 106 9.3.1 Incomplete Dominance In monohybrid cross when F1 is intermediate (between the parents), does not resemble either of the parents is called incomplete dominance. In dog flower (Antirrhinum - Snapdragon) crossing of pure red (RR) and pure white (rr) results in pink (Rr). Similar like Mendelian monohybrid cross, even during incomplete dominance F2 genotypic ratio is 1(RR) : 2(Rr) : 1(rr). But phenotypic ratio is not 3 : 1, it is 1Red : 2Pink : 1White. During incomplete dominance F2 progeny both phenotypic and genotypic ratios are same i.e.1 : 2 : 1. P Generation Red RR White rr × Gametes R r F1 generation Pink Rr Gametes ½ R ½ r Eggs ½ R ½ r F2 generation ½ R Sperms RR ½ r Rr Rr rr Figure: Results of monohybrid cross in the plant snapdragon where one allele is incompletely dominant over the other allele. 9.3.2 Co-dominance: In monohybrid cross when F1 hybrids resembles both the parents is called co-dominance. Good examples are different types of red blood cells that determine ABO blood grouping in human beings and seed coat pattern and size in lentil plants. Lentil [Lens culinaris ssp. culinaris (Medik) Williams] is a major grain legume (pulse) crop in North America. A cross between pure-breeding spotted (having few big irregular patches) lentils and pure-breeding dotted (having several small circular dots) lentils NARAYANAGROUP UNIT - III :GENETICS SR.BOTANY EAMCET - VOL - I Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION produce heterozygotes that are both spotted and It depends as much on the gene product and the dotted. The F1 show the phenotypic features of production of a particular phenotype from this both parents(the alleles are termed co-dominant). product. It also depends on particular phenotype Self-pollination of the spotted/dotted F1 generation that we choose to examine, in case more than produces F2 progeny in the ratio of 1 spotted: 2 one phenotype is influenced by the same gene. spotted & dotted : 1 dotted. 9.3.3 Concept of dominance Once again, because the heterozygotes can be Every gene contains the information to express a distinguished from both homozygotes, the particular trait. In a diploid organism, there are phenotypic and genotypic ratios coincide. two copies of each gene, i.e., as a pair of alleles. Now, these two alleles need not always be identical, (eg. a heterozygote). One of them may Parents CSCS CDCD be different due to some changes that it has undergone which modifies the information that the particular allele contains. Gametes CD CS Dominance is due to the work of a gene or what a gene does. Gene contains the information to express a trait through an enzyme. In heterozygous condition each allele expresses to produce one specific enzyme and so two enzymes F1(all identical) CSCD × CSCD are produced. The enzyme produced by the normal allele. converts substrate into product so the same CS CD F2 phenotype would be the result. CS S S S D Theoretically, the modified allele could be CC CC responsible for the production of, D C S D D D (i) the normal/less efficient enzyme, or CC CC S S (ii) a non-functional enzyme, or 1 C C (spotted): S D (iii) no enzyme at all 2 C C (spotted & dotted): D D The phenotype/trait will only be dependent on the 1 C C (dotted) functioning of the unmodified allele. The Pleiotropy: Occasionally, a single gene unmodified (functioning) allele, which represents product may produce more than one effect so the original phenotype is the dominant allele and that a single gene may be related to more than one the modified allele is generally the recessive character. Such phenomenon is called Pleiotropy. allele. Eg: Starch synthesis in pea seeds is controlled by one gene. It has two alleles B and b. Large starch grains (Starch synthesised effectively) PRACTICE TEST-IV - BB Smaller starch grains(lesser efficiency in starch 59. When F1 in monohybrid cross is intermediate synthesis) - bb. between the parents phenotypically and does After maturation of the seeds, BB seeds are not resemble them it is due to round where bb seeds are wrinkled. 1) Dominance 2) Heterozygous Heterozygotes (Bb) produce round seeds and 3) Incomplete dominance 4) Recessive starch grains with intermediate size. So B seems to be the dominant allele. But, the 60. The F1 progeny of a cross between pure red starch grains produced are of intermediate size in and pure white in dog flower seeds of heterozygotes (Bb). So if starch grain 1) Red 2) White 3) Pink 4) Yellow size is considered as the phenotype, then from 61. In incomplete dominance genotypic ratio this angle, the alleles show incomplete dominance. 1) 1 : 1 : 1 2) 1 : 2 : 1 Therefore, dominance is not an autonomous feature 3) 3 : 1 : 1 4) 2 : 1 : 1 of a gene or the product that it has information for. NARAYANAGROUP 107 UNIT - III :GENETICS SR.BOTANY EAMCET - VOL - I Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION seed shape also segregated in 3:1 ratio; just like 62. In incomplete dominance phenotypic ratio 1) 1 : 1 2) 3 : 1 3) 1 : 2 : 1 4) 1 : 0 in a monohybrid cross. 63. Dominance is mainly depends on In F2 there were four phenotypes i.e, yellow,, 1) Structure of the gene round, yellow wrinkled, green round and green 2) The product of the gene wrinkled. In the proportion of 9 : 3 : 3 : 1. 3) Phenotype produced by the product Yellow round and green wrinkled are parental 4) 1 or 2 or 3 combination. Yellow wrinkled and green round 64. The genotype causing wrinkled seeds in pea are recombinants. plant P generation 1) BB 2) bb 3) Bb 4) 1,2,3 Wrinkled green Round yellow 65. The genotype of seeds in pea phenotypically rr yy RR YY similar to dominant but with intermediate × ry Gametes RY size starch grains in seeds is 1) bb 2) Bb 3) BB 4) yy 66. How many different types of gametes can be Round yellow F generation Rr Yy formed by F1 progeny, resulting from the Selfing following cross: AA BB CC aa bb cc 1) 3 2) 8 3) 27 4) 64 RY RY In Lentil the pure-breeding spotted seeds 67. Gametes Gametes rY rY bear RRYY 1) Few small irregular patches Ry Ry RrYY RrYY 2) Several small circular patches ry ry RRYy rrYY RRYy 3) Few small circular patches 4) Few big irregular patches RrYy RrYy RrYy RrYy F generation 68. The phenomenon of a gene responsible for rrYy RRyy rrYy more than one function is Rryy Rryy 1) Dominance 2) Pleiotropy 3) Incomplete dominance 4) Co-dominance rryy 69. Seed coat pattern and size in Lentil plants Phenotypic ratio: round yellow: round green: wrinkled yellow: wrinkled green are good example for 9 3 3 1 1) complete dominance 2) co-dominance In dihybrid cross F2 progeny 3) Incomplete dominance4) dominance phenotypic ratio : 9 : 3 : 3 : 1 9.4 Inheritance of two Genes (Digenotypic ratio: 1 : 2 : 2 : 4 : 1 : 2 : 1 : 2 : 1 hybrid Cross) Probability of the F2 Genotypes and Cross conducted between parents different in two Phenotypes of a Dihybrid Cross : The nine characters is called dihybrid cross. genotypes of F2 generation for the two genes are Crossing of true breeding yellow, round seeded the products of three genotypes for each gene as pea plant with green, wrinkled is an example of shown below : dihybrid cross or inheritance of two genes. Gene 1 Gene 2 Probabilities Phenotypes F1 plants of dihybrid cross are similar to dominant of genotypes phenotype i.e., yellow and round seeds. 1/4 RR × 1/4 YY 1/16 RRYY Round Yellow Similar to monohybrid cross, even in dihybrid 2/4 Yy 2/16 RRYy Round Yellow cross F1 hybrids expresses only dominant 1/4 yy 1/16 RRyy Round Green phenotype. YYRR and yyrr are the genotypes of pure yellow, 2/4 Rr × 1/4 YY 2/16 RrYY Round Yellow round and green, wrinkled parents respectively. 2/4 Yy 4/16 RrYy Round Yellow The gametes of parents, during the formation of 1/4 yy 2/16 Rryy Round Green F1 are (YR) and (yr). So the genotype of F1 is 1/4 rr × 1/4 YY 1/16 rrYY Wrinkled Yellow YyRr. 2/4 Yy 2/16 rrYy Wrinkled Yellow When Mendel self pollinated the F1 plants, he 1/4 yy 1/16 rryy Wrinkled Green found that 3/4th of F2 plants had yellow seeds and 1/4th had green. The yellow and green colour segregated in 3:1 ratio. Round and wrinkled 1 2 108 NARAYANAGROUP UNIT - III :GENETICS SR.BOTANY EAMCET - VOL - I Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION 25%. The combination of gametes (Egg and pollen The probabilities of the F2 phenotypes of a selfed grain) results in four types of phenotypes and F1 dihybrid is a product of the probabilities of the nine types of genotypes. separate selfed F1 monohybrid phenotypes i.e; 3/ Among the four types of plants(phenotypes) 4 : 1/4 produced in dihybrid cross, 9 are double dominant Gene 1 Gene 2 Probabilities phenotype, 6 with one dominant and one recessive of Phenotype and one is double recessive. 3/4 Round × 3/4 Yellow 9/16 Round Yellow Among the six single dominant each dominant trait 1/4 Green 3/16 Round Green is found in 3. i.e., colour dominant 3, shape dominant 3. 1/4 Wrinkled × 3/4 Yellow 3/16 Wrinkled Yellow Mendel’s independent assortment will not apply 1/4 Green 1/16 Wrinkled Green to two genes on the same chromosome or when These 9 : 3 : 3 : 1 ratios for the pairs of traits are the genes are linked. independent of one another and that combinations Relation among pairs of independent alleles, turn up as expected according to chance. gametes, F2 genotypes and F2 phenotypes F2 phenotypic ratio 9 : 3 : 3 : 1. when dominance is present. F2 genotypic ratio 1 : 2 : 2 : 4 : 1 : 2 : 1 : 2 : 1. No. of No. of No. of No. of Number of types of phenotypes = 4 Heterozygous kinds of types of F2 types of F2 Number of types of genotypes = 9 pairs gametes Genotypes Phenotypes Ratio of double heterozygous to double 1 2 3 2 homozygous (4 : 4) 1 : 1 Number of offspring phenotypically similar to 9 4 2 4 F1 = 9 Number of offspring genotypically similar to 3 8 27 8 F1 = 4 4 16 81 16 In F2 the ratio between parental types to 10 1024 59059 1024 recombinants (phenotypically) = 10 : 6 (5 : 3) F2 Phenotypes Each parent forms four types of gametes n 2n 3n . The punnett square has 16 boxes. Based upon dihybrid cross results Mendel proposed the law of independent assortment. 9 Genotypes 9.4.1-Law of Independent Assortment: YYRR 1 YYRr, YYRr 2 YyRR, YyRR 3 YyRr, YyRr, YyRr, YyRr 4 YYrr 1 Yyrr, Yyrr 2 yyRR 1 yyRr, yyRr 2 yyrr 1 The law states that when a pair of contrasting traits are combined in a hybrid (RrYy) the segregation (or) separation of pair of characters is independent of other pair of characters. Segregation of factors within Rr and Yy and also between the pairs are independent during meiosis (Rr and Yy) Segregation within Rr and Yy is 50% and results in 4 types of gametes. . 1 The frequency of each type of gamete is or 4 NARAYANAGROUP 2n Genotypic Phenotypic ratio ratio 9 Yellow, round 3 Yellow, wrinkled 3 Green, round 1 Green, wrinkled 109 UNIT - III :GENETICS Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION PRACTICE TEST-V 70. When parents used in a cross are different in a pair of contrasting characters the cross is called 1) Monohybrid cross 2) Dihybrid cross 3) Trihybrid cross 4) Test cross 71. In pea plant the progeny of a cross between yellow round and green wrinkled is called 1) Monohybrid 2) Trihybrid 3) Dihybrid 4) Nullisomic 72. The phenotype of F1 in dihybrid cross is 1) similar to dominant 2) similar to recessive 3) intermediate to parents 4) dissimilar to parents 73. Which of the following type of gametes is not formed in Mendels dihybrid cross 1) YR 2) Yr 3) yR 4) rr 74. Phenotypic ratio of F2 in dihybrid cross 1) 9 : 3 : 3 : 1 2) 1 : 1 : 1 : 1 3) 6 : 3 4) 9 : 7 75.Genotypic ratio of dihybrid cross 1) 1 : 2 : 2 : 4 : 1 : 2 : 1 : 2 : 1 2) 1 : 3 : 3 : 4 : 1 : 2 : 1 : 2 : 1 3) 1 : 1 : 1 : 1 4) 9 : 3 : 3 : 1 76.The percentage of gametes with (Yr) genotype formed from F1 1) 50% 2) 25% 3) 75% 4) 100% 77. Percentage of genotypes with YyRr in F2 generation 1) 6.25% 2) 12.5% 3) 18.75% 4) 25% 78. Which among the given genotypes in F2 of dihybrid cross respresent 6.25% 1) yyRR 2) YyRr 3) yyRr 4) YYRr 79. A dihybrid condition is 1) tt Rr 2) Tt rr 3) tt rr 4) Tt Rr 80. Gametes of AaBb individual can be 1) Aa, Bb 2) AB, ab 3) AB, ab, aB 4) AB, Ab, aB, ab 81. Mendel's law based on results of dihybrid cross is 1) Segregation 2) Polygenic inheritance 3) Independent assortment 4)Dominance 82. Mendel's law of independent assortment can be demonstrated by 1) Test cross 2) Back cross 3) Monohybrid cross 4) Dihybrid cross 110 SR.BOTANY EAMCET - VOL - I 83. In the F2 generation of dihybrid cross, number of double dominant homozygous individuals is/are 1) 1 2) 2 3) 3 4) 4 84. In F2 generation of dihybrid cross what is the possibility for heterozygosity for two characters 1) 1/16 2) 8/16 3) 4/16 4) 9/16 85. In a cross, offsprings were 25% yellow round, 25% yellow wrinkled, 25% green round, 25% green wrinkled. Of which cross these results were obtained 1) YYRR x yyrr 2) YyRr x YyRr 3) YyRR x yyrr 4) YyRr x yyrr 86. How many types and in what ratio gametes will be formed in a plant which is heterozygous for two characters ? 1) Four types, 9:3:3:1 2) Two types, 3:1 3) Three types, 1:2:1 4) Four types, 1:1:1:1 87. In a typical dihybrid cross in pea plants with TTaa and ttAA, 560 pea plants are formed in F 2 generation. The expected number of progeny homozygous for only tallness is 1) 280 2) 60 3) 120 4) 140 88. When two hybrids rrTt and Rrtt are crossed, the phenotypic ratio of offspring shall be 1) 3 : 1 2) 1 : 1 : 1 : 1 3) 1 : 1 4) 9 : 3 : 3 : 1 9.5 Chromosomal Theory of Inheritance Mendel laws was not accepted by contemporary biologists of those days, because 1.Mendel proposed that heredity is under the control of factors (now called genes). The factors controlling a trait occur in pairs. They do not blend or mix. They segregate or separate and enter into different gametes (It is not accepted by contemporaries due to appearance of continuous variations in nature). 2.Lack of wide publicity due to shortage of easy communication. 3.Rejection of mathematical approach to explain biological phenomena. 4.Failure of Mendel to show physical existence of genes or their composition are the reasons for not accepting Mendel’s theory of heredity. Hugo de Vries, Correns and Van Tschermak rediscovered independently Mendel’s laws. Microscopy helped to observe chromosome (coloured bodies) doubling and division just before each cell division. Chromosome movement during cell division had been worked out (both in mitosis and meiosis). NARAYANAGROUP UNIT - III :GENETICS SR.BOTANY EAMCET - VOL - I Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION Walter Sutton and Theodore Boveri proposed Anaphase-I of Meiosis acts as cytological evidence to Mendel’s theory of segregation. chromosomal theory of inheritance (i.e, Meiosis I - anaphase Meiosis I - anaphase chromosomes are physical basis of heredity) after observing close similarity, behaviour of chromosomes was parallel to the behaviour of genes predicted by Mendel. They explained Mendel laws by using the movement of chromosomes during cell division. Genes are located on chromosomes and alleles of Meiosis II - anaphase Meiosis II - anaphase a gene are at homologous site (locus) on homologous chromosomes. Sutton and Boveri explained pairing (synopsis) and separation of homologous chromosomes (disjunction) would lead to separation of factors they carried during meiosis. Germ cells Germ cells During Metaphase of meiosis-I, the two chromosome pairs can align at the metaphase plate independently of each other. Hence they united the knowledge of chromosomal segregation and Mendelian principles. This is called chromosomal theory of inheritance. G1 G2 Meiosis I anaphase Meiosis II anaphase Germ cells Bivalent meiosis and germ cell formation in a cell with four chromosomes. Can you see how chromosomes segregate when germ cells are formed? Chromosomes Genes i) Occur in pairs i) Occur in pairs ii) Separate during ii) Separate at gametogenesis gamete formation such that only one and only one of of each pair is each pair is transferred to a transmitted to a gamete. gamete (as one iii) Independent pairs on a segregate chromosome). independently of iii) One pair each other segregates independently of iv) They retain their another pair number, structure iv) They retain their and individuality number, structure throughout their and individuality life and from one throughout their generation to the life and from one next. NARAYANAGROUP Independent assortment of chromosomes TH Morgan through his experiments on Drosophila verified chromosomal theory of inheritance and demonstrated that cause of variation lies in sexual reproduction and proposed linear arrangement of genes on chromosomes. Short life span, production of many offspring by single mating, clear and easy recognition of male and female insects and easy observation of variations, helped Morgan’s work on Drosophila. Any structural change in chromosome (deletion , addition) brings structural or functional changes in organisms. This is an additional evidence that genes are on chromosomes. Morgan proved that certain characters are sex linked and associates with 'X’ or 'Y' chromosomes. PRACTICE TEST-VI 89. Mendel’s work remained unrecognised for many years because 1) Shortage of easy publicity in Mendel’s days 2) Biologists of the day did not accept Mendel’s explanation as the cause of continuous variations. 3) Mendel could not provide for the physical existence of his factors controlling traits. 4) 1,2,3 90. Mendel’s laws were rediscovered by 1) Sutton and Boveri 2) TH Morgan and Bridges 3) Waldeyer and Hofmeister 4) de Vries, Correns and Tschermak. 111 UNIT - III :GENETICS Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION 91. Behaviour of chromosomes is parallel to behaviour of 1) nucleus 2) genes 3) centriole 4)spindle fibres 92. Parallelism between chromosomes and genes was explained by 1) Mendel 2) Johanssen 3) Sutton & Boveri 4) Correns 93. Genes are located on 1) Cells 2) Tissues 3) Chromosomes 4) Nucleolus 94. Pairing of homologous chromosomes occurs during 1) Pachytene 2) Zygotene 3) Leptotene 4) Diakinesis 95. Chromosomal theory of inheritance is proposed by 1) Watson and Crick 2) Sutton and Boveri 3) Morgan and Mendel 4) Hershey and Chase 96. Which of the following occur in pairs 1) Chromosomes 2) Genes 3) Both 1 and 2 4) RNA 97. Morgan worked on Drosophila because 1) Short life span 2) Production of many offspring by single mating 3) Clear and easy recognition of male and female insects 4) 1,2,3 98. Cytological evidence to Mendel’s theory of segregation is 1) Anaphase-I 2) Anaphase-II 3) Metaphase-II 4) Metaphase-I 99. Sutton and Boveri explained Mendel’s laws by using 1) Movement of chromosomes during cell division. 2) Movement of nuclei during cell division 3) Movement of cell organelles during cell division 4) Movement of proteins during cell division 100. Who united the knowledge of chromosomal segregation with Mendelian principles 1) Boveri only 2) Sutton & Boveri 3) Morgan 4) Sutton only 9.6 Linkage and Recombination An organism has many traits each controlled by a factor or gene but has limited chromosomes. Hence a chromosome has many genes. Morgan and his co workers through their experiment on Drosophila hypothesized that certain hereditary characters are sex linked. This is revealed by monohybrid cross, where the F1 results of normal cross and reciprocal cross are different. 112 SR.BOTANY EAMCET - VOL - I Like Mendel, T.H. Morgan carried out dihybrid crosses in Drosophila (fruit fly) to study the heredity of sex linked characters. Grey body (brown), Red eye and long winged insects are normal and called wild. Yellow body, white eye and miniature winged are mutants. Wild are dominant and shown '+' as superscript. All these characters are sex linked. Hence normal cross and reciprocal cross results will be different. In his first dihybrid cross T.H. Morgan crossed brown bodied, red eyed males W Y with yellow bodied, white eyed female mutant (wy) and inter crossed their F1 progeny.. In F1 all males are white eyed and yellow bodied (wy) and all females are wild type heterozygous brown bodied, red eyed colour (W+wY+y). This indicated that Y W genes of parent male are not on "Y" chromosome but only on 'X" chromosome. In F2 Morgan found 4 types of insects. 2 male types and 2 female types. Among them parental combination 98.7% and recombinant types 1.3%. This is a deviation from 9 : 3 : 3 : 1 ratio of G.J. Mendel’s dihybrid ratio. Morgan coined the name linkage and gave linkage as the reason for the appearance of more parental combinations. When two genes W Y or yw are on the same chromosomes, the proportion of parental combinations are much higher than nonparental combination or recombination. The physical association of genes on a chromosome is called linkage. On the same chromosome some genes are very tightly linked some are loosely linked. The strength of linkage depends on the distance between genes. The farther are the genes, the weaker is the linkage, the nearer are the genes the stronger is the linkage (inversely related). T.H. Morgan conducted second dihybrid cross between white miniature winged female wild male (grey bodied, large winged). In F1 all females were wild and all males are white eyed, miniature wings. This indicated that genes are only on X chromosome and not on Ychromosome. NARAYANAGROUP UNIT - III :GENETICS SR.BOTANY EAMCET - VOL - I Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION Cross A Cross B w + y w+ yw Parental yw Yellow,white + w m w m white, miniature Wild type m + Wild type Chromosome Mapping: yw yw w F1 generation + + + w yw Wild type Yellow,white m + m Wild type w m + + yw Wild type yw Yellow,white Recombinant Parental Recombinant types(1.3%) type(62.8%) types(37.2%) + yw white + + + w m Wild type yw w m Yellow White, miniature White miniature Gametes Parental type(98.7%) w+ m Miniature w m+ white + + yw yw Wild type white + w m+ w m Wild type + w m w m miniature yw w m w m yw yw w m w m White, miniature White + Yellow Figure shows linkage: Results of two dihybrid crosses conducted by Morgan. Cross A shows crossing between gene Y and W; Cross B shows crossing between genes w and m. Here dominant wild type alleles are represented with (+) sign in superscript. Note: The strength of linkage between y and w is higher than w and m. Wild type: has dominant phenotypes for both characters (brown body and red eye) White: had dominant phenotype(wild colour) for body colour but recessive phenotype for eye colour. Yellow: had recessive phenotype for body colour (yellow) but dominant phenotype ( wild character) for eye colour(red). He intercrossed the F1 to form the F2 with four types of insects (2 female type + 2 male types). He recorded 62.8% parental combination and 37.2% recombination. This proved that genes for wing size and body colour are loosely linked. Morgan gave recombination as the reason for the higher percentage of new combinations. NARAYANAGROUP + yw Yellow,white + yw Alfred Sturtevant student of Morgan mapped the positions of genes on a chromosome. He used the frequency of recombination in crosses (percentage) between the gene pairs as a measure of the distance between genes and mapped and determined their position on a chromosome. The genetic maps are starting points in the sequencing of whole genome as was done in the case of the Human Genome Sequencing Project (HGSP) The generation of non-parental gene combinations is recombination. 9.7 Mutations F2 generation yw Crossing over in pachytene stage of Meiosis and disjunction in Anaphase-I gives cytological evidence for recombination. In Drosophila for those given characters crossing over occurs in females only. Mutation is a phenomenon which results in alteration of genes (DNA sequences) and consequently results in changes in the genotype and the phenotype of an organism. In addition to recombination, mutation is another phenomenon that leads to variation in DNA. Mutation were first noticed by Hugo de Vires in the plant Oenothera lamarckiana (Lamarck’s evening primrose). One DNA helix runs continuously from one end to the other in each chromatid in a highly supercoiled form. Therefore loss (deletions) or gain (insertion/duplication) of a segment of DNA results in alteration in chromosomes. Since genes are known to be located on chromosomes, alteration in chromosomes results in abnormalities or aberrations. Chromosomal aberrations are commonly observed in cancer cells. In addition to the above, mutations also arise due to change in a single base pair of DNA. This is known as point mutation. A classical example of such a mutation is sickle cell anemia. Deletions and insertions of base pairs of DNA cause frame shift mutations. There are many chemical and physical factors that induce mutations. These are referred to as mutagens. UV radiations can cause mutations in organisms it is a mutagen. Significance of Mutations Mutations generate a large amount of variability in a population from which a breeder can select 113 UNIT - III :GENETICS Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION the desirable types. Hence improved varieties of crop plants with several desirable characters can be obtained after careful selection and hybridization. H ots Red iscove ry of M en del’s W ork (the birth of Gen etics) It w as in 1900 that three scie ntists indepe ndently rediscovered the principles of heredity already w orked out by M e ndel. T hey were :– i)Karl Correns (G ermany – W orked on maiz e Zea m ays) ii)H ugo de Vries(H olland – Worked on evening primrose Oenother a). iii)E rich von T scherm ak (A ustria – Wo rked on flow ering plants). Eugenics and Euphenics are branches of human genetics. The former deals with application of genetics knowledge for improvement of human rays and the later deals with phenotypic improvement of humans after birth. 101.Sex linked inheritance in Drosophila studied by 1) T.H. Morgan 2) G.J. Mendel 3) de Vries 4) Hofmeister 102.Which of the following is representing wild female pure parent for red eyed W+ 2) 1) 3) + W W X Y X W X W + + X 4) Y SR.BOTANY EAMCET - VOL - I 105. When a dihybrid cross is conducted between brown bodied red eyed males (wild) with yellow bodies white eyed female (m) in F1 all males are white eyed because Y W genes of parents are on 1) X chromosome only 2) Y chromosome only 3) both X and Y chromosomes 4) Autosomes 106. Parental types are 98.7 and recombinant types are 1.3% in a dihybrid cross F2 . This indicates 1) Independent assortment 2) Higher percentage of crossing over 3) 100% linkage 4) Linkage in most of the genes 107. Term linkage coined by 1) G.J. Mendel 2) Bateson 3) Johanssen 4) T.H. Morgan 108. Physical association of a genes on a chromosome is called 1) Dominance 2) Independent assortment 3) Linkage 4) Crossing over 109. Strength of linkage is inversely proportional to 1) distance between locii 2) distance between telomeres 3) distance between chromatids 4) distance between pairs of chromosomes 110. Starting point in gene sequencing is 1) Chromosome mapping 2) Crossing over 3) Linkage 4)Chromosome tracing EXERCISE - I W (Check Your Memory) 111. Mendel was a/an 103. When white eyed female is crossed with wild 1) Austrian 2) Australian 3)American 4)German (red eye) in the F1 112. A gene is a 1) All are wild 2) All are white eyed 1) Complete DNA molecule 2) Specific part of a DNA molecule 3) Heterochromatic part of 3) All males are red eyed DNA 4) Set of ribonucleotides 4) All females are red eyed 104. Which of the following is not a mutant character 113. Genome is a 1) diploid set of chromosomes 2) haploid set in Drosophila of chromosomes 1) White eye 2) Miniature wing 3) set of genes lying closely on a chromosome 3) Yellow body 4) Brown body 4) set of genes present in homo logo us chromosomes 114 NARAYANAGROUP UNIT - III :GENETICS SR.BOTANY EAMCET - VOL - I Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION 114. The unit of heredity is 1) Chromosome 2) Nucleus 3) DNA and RNA molecules 4) Gene 115. The segregation of the paired genes occur during 1) interphase between two meiotic divisions 2) metaphase of first meiotic division 3) anaphase of first meiotic division 4) interkinesis 116. Offsprings are not exactly similar to parents because of 1) variations produced by crossing over at the time of gamete formation 2) variations produced by chance distribution of chromosome 3) both 1 and 2 4) neither 1 nor 2 117. Which one of the following pairs is not of a contrasting character 1) Tall and dwarf 2) Axial and terminal 3) Green and yellow 4) Round and oval 118. F1 hybrids contain 1) two different genes of a contrasting pair of characters 2) single gene of only one character 3) two genes of same character 4) single gene for all characters. 119. The process of removing stamens from flowers during hybridization is 1) crossing 2) selfing 3) emasculation 4) bagging 120. Which is the source of variations 1) Mutation 2) Recombination 3) Deletion 4) 1, 2 and 3 121. A Phenotypically round, yellow pea plant is test crosssed with rryy, in the obtained progeny the ratio of round yellow & round green is 1:1 then the genotype of the plant tested is 1) RRyy 2) RrYY 3) RRYy 4) RrYY 122. When true breeding yellow, wrinkled seeded pea plant is crossed to true breeding green, round seeded pea plant. The progeny will be 1) All yellow, round 2) All yellow, wrinkled 3) All green, round4) All green, wrinkled 123. The entire body of molecular biology was a consequent development with major contribution from 1) Watson, Crick, F.W.Went, Skoog, Kornberg, Benzer, Monod, Brenner. 2) Watson, Crick, F.W.Went, Skoog, Kornberg, Calvin, Monod, Brenner. 3) Watson, Crick, F.W.Went, Skoog, Kornberg, Calvin, Monod, Mitchell. 4) Watson, Crick, Nirenberg, Khorana, Kornberg, Benzer, Monod, Brenner. NARAYANAGROUP 124. It is exception to Mendel’s laws 1) Purity of gametes 2) Dominance 3) Linkage and crossing over 4) Independent assortment 125. Mendel’s work on inheritance of two genes states that 1) In fertilization the combining of sperm and eggs is random 2) In meiosis, crossing over creates genetically diverse gametes 3) In any dihybrid cross, it is possible to get any combination of phenotypes 4) During gametes formation, gene pairs are transmitted independently of each other 126. One of Mendel’s pure strains of pea plants had green peas. How many different kinds of eggs could such a plant produce with regard to pea colour 1) 1 2) 2 3) 4 4) 8 127. In Pisum sativum, ___ form of seed is dominant character. 1) wrinkled 2) round 3) yellow 4) green 128. The characters that appear in the first generation are called 1) recessive characters 2) dominant characters 3) both recessive and blend characters 4) 2 and 3 129. Mendelian laws of heredity include 1) gene linkage, segregation and independent assortment 2) gene linkage, dominance and independent assortment 3) segregation, dominance and independent assortment 4) segregation, independent assortment and recombination 130.An offspring of two homozygous parents differing from one another by alleles at only one gene locus is 1) back cross 2) monohybrid 3) dihybrid 4) trihybrid 131.A pure tall pea plant can be differentiated from hybrid tall by 1) Treating with GBA 2) Measuring and comparing height 3) Selfing and noticing that all progeny is tall 4) Selfing and noting that all progeny is short 132.A testcross is done to find out 1) the genotype of an individual by examining the phenotypes of its offsprings from a particular mating 2) the genotype of an individual for testing for its DNA content 3) whether a mating is fertile 4) whether two species can interbreed 115 UNIT - III :GENETICS Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION 133.The phenomenon of incomplete dominance was observed in 1) Pea 2) Snapdragon 3) Lentil 4) Maize 134.In co-dominance, genotypes of F1 hybrids 1) C S C D 2) C S C S 3) C DC D 4) Both C S C S and C DC D 135.Pink coloured flowers are obtained from a cross between a red flower pea plant and white flower pea plant. The appearance of this pink colour character is known as 1) co-dominance 2) complete dominance 3) incomplete dominance 4) segregation 136.Emasculation is 1) done for obtaining mixed breeds 2) done for obtaining hybrids 3) done for cloning 4) done for autogamy 137.The phenomenon of segregation and independent assortment occurs in 1) meiosis I during gamete formation 2) zygote division 3) segregation during meiosis I and independent assortment of characters during fusion 4) fusion of male and female gametes 138.A monohybrid cross between two plants, one having 24 cm long internodes and the other having 12 cm long internodes, produced F1 hybrids all having 18 cm long internodes. This is a case of 1) co-dominance 2) incomplete dominance 3) incomplete dominance 4) multiple allelism 139.When a red (RR) flowered plant is crossed with white (WW) flowered plant. all the off spring of F1 generation are pink. It indicates that ‘R’ gene is 1) Hybrid 2) Incompletely dominant 3) Complete dominance 4) Recessive 140.If a dwarf variety of pea plant was treated with GA, it grew as tall as the pure tall pea plant. On selfing the phenotypic ratio is likely to be 1) all dwarf 2) all tall 3) 50% tall 4) 75% tall; 25% dwarf 141.Rarely observed phenotype in population is called 1) wild type 2) mutant type 3) variant type 4) recombinant type 142.Heterozygosity can be ascertained by 1) back cross 2) reciprocal cross 3) blending inheritance 4) multiple crossing 116 SR.BOTANY EAMCET - VOL - I 143 Allele is called 1) a pair of contrasting characters 2) pair of homologous chromosomes 3) one of the alternative forms of a gene 4) physical appearance of an individual 144.In Antirrhinum, when a cross is made between red and white flowers all resultant flowers are 1) red 2) pink 3) white 4) both 1 and 2 145.A red and tall dominant character hybrid plant (Rr Tt ) is crossed with recessive white dwarf plant (rr tt). What will be the ratio of respective four combinations : red tall, red dwarf, white tall and white dwarf plants in the next generation ? 1) 9 : 3 : 3 :1 2) 15 :1: 0 : 0 3) 9 : 3 : 4 : 0 4) 1 : 1 : 1 : 1 146.‘Gametes are never hybrid’. This is a statement of law of 1) dominance 2) independent assortment 3) segregation 4) random fertilization 147.In a dihybrid test cross of Pisum 300 yellow round seeds, 302 yellow wrinkled seeds, 302 green round seeds and 299 green wrinkled seeds are formed, the percentage of recombinants is 1) 25 % 2) 75 % 3) 50 % 4) 12.50 % 148.If heterozygous tall plant is crossed with a homozygous dwarf plant, then the percentage of dwarf plant is 1) 25% 2) 50% 3) 75% 4) 100% 149.Mendel started his experiments on pea plants at 1) Brno 2) Olmutz 3) Australia 4) San Francisco 150.In dihybrid crosses the F1 heterozygous plants are self fertilized to produce F2 generation and if offsprings are computed in punnett square the phenotypic F2 ratio as per Mendel’s independent assortment will yield. 1) 9 : 7 2) 9 : 3 : 3 :1 3) 9 : 6 :1 4) 12 : 3 :1 151.Number of linkage groups in Pisum sativum 1) 2 2) 4 3) 7 4) 8 152.The commonly used animal in genetics is 1) Escherichia 2) Drosophila 3) Neurospora 4) Chlorella 153.Which one of the following pairs consists of both recessive traits in Pisum sativum as studied by Mendel 1) Dwarf plant and axial flower position 2) Constricted pod shape and round seed shape 3) Green seed colour and terminal flower position 4) White flower and yellow seed colour NARAYANAGROUP UNIT - III :GENETICS SR.BOTANY EAMCET - VOL - I Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION 154.Ratio between number of chromosomes and linkage groups in the meiocyte of Pisum 1) 2 : 1 2) 1 : 1 3) 1 : 2 4) 7 : 1 155.The percentage of yr gametes in YyRr is 1) 25% 2) 50% 3) 75% 4) 100% 156.Phenotype of an organism is the result of 1) genotype and environment interactions 2) mutations and linkages 3) cytoplasmic effects and nutrition 4) environmental changes and sexual dimorphism 157.Test cross involves 1) crossing between two genotypes with dominant trait 2) crossing between two genotypes with recessive trait 3) crossing between two F1 hybrids 4) crossing the F1 hybrid with recessive genotype 158.Mendel crossed tall, round seeded plant with dwarf , wrinkled seeded plant. In F2 generation he saw 1/16 were dwarf and wrinkled seeds. What did he conclude from this 1) Short and wrinkled show linkage 2) Tall and wrinkled never combine 3) They show independent assortment 4) Tall and dwarf are blended 159.A true breeding plant producing red flowers is crossed with a pure plant producing white flowers. Allele for red colour of flower is dominant. After selfing the plants of first filial generation, the proportion of plants producing white flowers in the progeny would be 1) 3/4 2) 1/4 3) 1/3 4) 1/2 160.Gene mutations is caused by 1) linkage 2)reproduction 3) changes in sequence of chromosome 4) changes in sequence of nitrogenous bases 161.Chromosomal aberrations are commonly observed in 1) Meristems 2) Cancer cells 3) Parenchyma cells 4) all dead cells 162.Mutations result in 1) change in phenotypes 2) change in genetic constitution 3) better varieties 4) 1, 2 and 3 163.Mutations bring about …. Change 1) small 2) large 3)negligible 4)1,2 and 3 164.Point mutations affect DNA’s 1) phosphate group 2) nitrogen base molecule 3) sugar molecule 4) 1, 2 and 3 165.A normal gene sequence in a chromosomal sequence is ABCDEFGH, if is changed to ACGH. This is a case of NARAYANAGROUP 1) frame-shift mutations 2) deletions 3) inversions 4) duplication 166.The ratio of yellow and green seeded progeny in F2 generation of a dihybrid cross according to Mendel is 1) 1 : 3 2) 3 : 1 3) 1 : 1 4) 9 : 7 167.The ratio between number of chromosomes in a diploid compliment of Pisum to the number of truebreeding lines selected by Mendel for his experiments 1) 1 : 7 2) 2 : 1 3) 1 : 14 4) 1 : 1 168 Morgan was the first man to 1) rediscover Mendel’s work 2) give association of a particular gene with a particular chromosome. 3) carryout controlled breeding experiments 4) observed recombination of chromosomes 169.F1 hybrid of a dihybrid cross is crossed with its dominant parental genotype and also with its recessive parental genotype. How many types of total genotypes and common types of genotypes are found in the resultant progeny 1) 7 & 1 2) 6 & 2 3) 6 & 1 4) 4 & 2 170.From a cross between RRYy X rrYy plants, the progeny plants with genotypes RrYY: RrYy:Rryy : rryy will be obtained in the following ratio 1) 1 : 1 : 1 : 1 2) 1 : 2 : 1 : 0 3) 1 : 3 : 1 : 0 4) 1 : 1 : 1 : 0 171.Mendel formulated the law of purity of gametes on the basis of 1) Monohybrid cross 2) Dihybrid cross 3) Test cross 4) Back cross 172.Behaviour of chromosomes during meiosis was linked to the Mendelian principles by 1) Devries & Correns 2) Bateson 3) Sutton & Boveri 4) Morgan 173.Genotypic ratio of round and yellow seeded pea plants in F2 generation of Mendelian dihybrid cross is 1) 9 : 3 : 3 :1 2) 1: 2 : 2 : 4 3) 1: 2 : 2 :1 4) 1: 2 174.Genotypic ratio of round and green seeded plants in F2 generation of Mendelian dihybrid cross is 1) 9 : 3 : 3 :1 2) 1: 2 : 2 : 4 3) 1: 2 : 2 :1 4) 1: 2 175.Among the progeny round and yellow are 3, round and green are 1, wrinkled and yellow are 3 and wrinkled and green are 1, find out the genotypes of the parents that produce the above combinations 1) Rr Yy x rr Yy 2) Rr Yy x rr yy 3) Rr Yy x Rr Yy 4) Rr yy x rr Yy 117 UNIT - III :GENETICS Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION 176.What is the ratio of F2 progeny of Mendel’s dihybrid cross which are double heterozygous to double homozygous to single homozygous 1) 4 : 6 : 6 2) 4 : 8 : 4 3) 4 : 4 : 8 4) 4 :1: 4 177.The set of genotypes of offspring which together constitute 8/16th of the total offspring of the cross Rr Yy Rr Yy 1) RR YY, rr yy, RR Yy, rr Yy 2) RR YY, Rr Yy, RR yy, rr yy 3) RR yy, Rr yy, rr Yy, rr yy 4) RR Yy, Rr YY, rr Yy, Rr yy 178.In a F2 generation of a dihybrid cross among the recombinants the ratio between heterozygous recombinants to homozygous recombinants is 1) 1:1 2) 1: 2 3) 4 : 2 4) 3 :1 179.All the genes located on a chromosome are called. 1) Multiple genes 2) Multiple alleles 3) Linked genes 4) Pleiotropic genes 180.If pink flowered snapdragon plant is crossed with a white flowered snapdragon plant the ratio of the pink flowered and white flowered off spring is expected to be 1) 3 :1 2) 2 :1 3) 1:1 4) 1: 2 181.Condition in which two alleles in a heterozygote show the individual expression of each allele in the phenotype is 1) Complete dominance 2) Partial dominance 3) Co-dominance 4) No dominance 182.Tallness (T) is completely dominant over dwarfness(t). Red colour (R ) of flower is incompletely dominant over white(r ), the heterozygote being pink. Plant having genotype of TtRr is self – pollinated. What would be the percent of plants with dwarf and pink character in its progeny? 1) 6.25% 2) 50% 3) 25% 4) 12.5% 183.Which pair of characters among the given are pleiotropic in Pisum 1) Seed shape 2) Pod colour 3) Flower colour 4) Size of starch grain 184.Incorrect statement among the following is 1) Mendel was first to consider results of hybridization in terms of single traits 2) Mendel compared his experimental proportions with mathematical models 3) Mendel’s experiments laid foundation for modern genetics 118 SR.BOTANY EAMCET - VOL - I 4) Mendel was the first person to perform hybridization experiments 185.F2 progeny can be obtained from F1 hybrid by this method 1) by crossing F1 hybrid and P1 recessive parent 2) by crossing F1 hybrid and P1 dominant parent 3)by crossing F1 hybrid of any two P1 generations 4) by selfing F1 hybrids 186.Checker board is also called 1) Mendel’s square 2) Punnett’s square 3) Bateson’s square 4) Morgan’s square 187.In a monohybrid cross, the F2 progeny show 3/ 4 proportion of tall plants and 1/4 proportion of dwarf plants. From the group of tall plants 1) 1/3 Proportion are heterozygous 2) 1/3 Proportion are homozygous 3) All are heterozygous 4) 2/3 Proportion are homozygous 188.Scientist who did not discover the Mendel’s paper presented on his experiments 1) Carl Correns 2) Morgan 3) Tschermak 4) Hugo de Vries 189.The correct genotypes of the parents used in P1 generation of a monohybrid cross based on the length of the stem are 1) TT Tt 2) Tt Tt 3) Tt tt 4) TT tt 190.The famous Indian breed Sahiwal cows belong to 1) Ongole 2) Karnataka 3) Punjab 4) Kerala 191.Number of true breeding pea plant varieties selected by Mendel 1) 70 2) 30 3) 14 4) 7 192.Find the mismatch from the following Character - Dominant trait 1. Pod colour Yellow 2. Flower position Axial 3. Pod shape Inflated 4. Seed colour Yellow 193.Selecting garden pea plant by Mendel is an advantage because1 1) It is a perennial plant with well defined characteristics 2) It is monoecious with both male & female flowers 3) It has papillionaceous corolla 4) It can be self fertilized conveniently 194.A cross was made between tall and dwarf plants. If F1 plants were selfed, the tall and dwarf plants appeared in 3:1 ratio in F2 generation. This phenomenon is known as 1) Linkage 2) Segregation 3) Hybridization 4) Crossing over NARAYANAGROUP UNIT - III :GENETICS SR.BOTANY EAMCET - VOL - I Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION 195.Which of the following characters of pea was not studied by Mendel 1) Length of stem 2) Colour of plant 3) Shape of pod 4) Colour of pod 196.Which term represents a pair of contrasting characters 1) Homozygous 2) Heterozygous 3) Complementary genes 4) Allelomorphs 197.The trait that is expressed in homozygous and heterozygous conditions 1) Co-dominant trait 2) Dominant trait 3) Recessive trait 4) Incomplete dominant trait 198.Monohybrid test cross ratio is 1) 1:3 2) 3:1 3) 1:1 4) 2:1 199.Mendel’s principle of segregation was based on the separation of alleles in the garden pea during 1) Embryonic development 2) Seed formation 3) Gamete formation 4) Pollination 200.Progeny are phenotypically and genotypically uniform in 1) F2 generation 2) F3 generation 3) F4 generation 4) F1 generation 201.A cross between a plant with any of the parents is called 1) Test cross 2) Back cross 3) Hybrid cross 4) Inbreed cross 202.Total types of gametes produced in monohybrid back cross of Tt and TT plants 1) One 2) Two 3) Three 4) None 203.The genotypic ratio and phenotypic ratio of back cross and test cross of a Mendelian monohybrid respectively 1) 3:1 and 1:1 2) 1:1 and 1:1 3) 1:3 and 3:1 4) 1:2 and 1:1 204.Mendel’s law of segregation is based upon the ratio of 1) 1:2 2) 3:1 3) 9:3:3:1 4) 1:1 205.When a tall pea plant is crossed to dwarf pea plant in the progeny all tall plants are produced, the tall plant is 1) Only heterozygous 2)Recessive alleles absent 3) Only homozygous 4) May be homozygous or heterozygous 206.In a typical monohybrid cross % of F2 progeny resembling the parents genotypically 1) 100 2) 75 3) 50 4) 25 207.In a typical monohybrid cross% of F2 progeny resembling the dominant parent phenotypically 1) 100 2) 75 3) 50 4) 25 NARAYANAGROUP 208.The ratio of homozygous and heterozygous organisms in the F2 progeny of monohybrid cross 1) 1:1 2) 3:1 3) 1:3 4) 1:2 209.The type of cross conducted to know the genotype of tall progeny 1) Back cross 2) Test cross 3) Monohybrid cross 4) Selfing of 210.Estimate the number of tall individuals in the progeny of 2000 individuals obtained by selfing the heterozygous plant in monohybrid cross 1) 1000 2) 1500 3) 500 4) 2000 211.Number of homozygous tall plants among 1000 individuals obtained by monohybrid test cross 1) 500 2) 1000 3) 750 4) Zero 212.Morgan hybridized yellow bodied, white eyed female Drosophila to brown bodied, red eyed male Drosophila and intercrossed their F1 progeny. He observed that 1. F2 ratio was deviated very significantly from the 9:3:3:1 ratio 2. Both the genes segregate independently of each other 3.Recombinant types are not obtained F2 generation 4. Parental types are not obtained in F2 generation 213.Which of the following phenomenon leads to variation in DNA 1. Linkage, Mutation 2.Recombination, Linkage 3. Mutation, Recombination 4. Aneuploidy, Linkage 214.Loss or gain of a segment of DNA results in 1. Frame shift mutation 2. Point mutation 3. Polyploidy 4. Linkage 215.Sickle cell anemia disorder arises due to 1. Duplication of segment of DNA 2. Substitution in a single base of DNA 3. Deletion of a segment of DNA 4. Duplication of in a base pair of RNA 216.Which one of the following is a physical mutagen 1. Colchicine 2.UV-rays 3. Formaldehyde 4. DES 217.Mutations first noticed in Oenothera lamarckiana by 1. Alfred Sturtevant 2. Morgan 3 Hugo de Vries 4. Muller 119 UNIT - III :GENETICS Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION 218.The law of independent assortment states that : 1) In fertilization , the combining of sperm and eggs is random. 2) In meiosis, crossing over creates genetically diverse gametes 3) In any dihybrid cross, it is possible to get any combination of phenotypes. 4) During gametes formation, gene pairs are transmitted independently of each other 219.In which type of mutation the length of the DNA increases 1. Deletion 2. Substitution of nitrogen base in DNA 3. 1 and 2 4. Insertion 220.Absence of independent segregation or deviation from 9:3:3:1 ratio in F2 indicates 1. Linkage 2. Dominance 3. Crossing over 4. Absence of sexual reproduction 221.The number of linkage groups in a cell having 40 pairs of chromosomes is 1. 20 2. 40 3. 30 4. 80 222.Number of linkage groups in a species is equal to the number of chromosomes in a 1. Genotype 2. Genome 3. Zygote 4. Spore mother cell 223.In a dihybrid cross between yellow round seeded plants and green wrinkled seeded plants, the number of F2 plants with ‘YyRr’ genotype 1. 1 out of 16 2. 2 out of 16 3. 4 out of 16 4. 3 out of 16 224.The organisms which has undergone a mutation is called 1. Mutagen 2. Mutant 3. Pure line4. Inbred line 225.In F2 progeny of dihybrid cross the expected genotypic proportions of individuals that are homozygous for both dominant characters is 1. 3/16 2. 9/16 3. 12/16 4. 1/16 226.If linkage was known at the time of Mendel which of the following law of Mendel was unable to explain 1. Law of dominance 2. Law of independent assortment 3. Law of segregation 4. Law of purity of gametes 227.From a cross YYRr x yyRr, the genotypes YyRR, YyRr, Yyrr, yyrr will be obtained in the following ratio 1. 1:1:1:1 2. 1:2:1:0 3. 1:3:1:0 4. 1:1:1:0 120 SR.BOTANY EAMCET - VOL - I 228.A and B genes are completely linked. What should be the genotype of progeny in a cross between AB/ab and ab/ab 1. AAbb and aabb 2. AaBb and aabb 3. ABB and aabb 4. 1 and 3 229.A plant of unknown genotype with yellow seeds and purple flowers is crossed to a plant with green seeds and white flowers. The offspring all have yellow seeds, but some have purple flowers and some have white flowers what is the genotype of yellow seeded, purple flowered plant 1) YyPp 2) Yypp 3) YYpp 4) YYPp 230.Study the following with regard to pleiotropy. The starch synthesis in pea plants is controlled by a single gene. It has two alleles B and b. BB homozygotes produced large starch grains as compared to that produced by bb homozygotes. After maturation it was observed that BB seeds were round and bb were wrinkled. When they were crossed, the resultant heterozygotes produced round seeds, but starch grains produced are of intermediate size in Bb seeds. According to the above information, correct statements of the following 1) The dominance is an autonomous feature of a gene or for the information that has. 2) If starch grain size is considered as the phenotype, the alleles show co-dominance 3) Dominance is not an autonomous feature of a gene or the product that has the information for ; it depends as much on the gene product and the production of a particular phenotype from this product 4) F2 progeny shows round and wrinkled seeds in 1 : 1 ratio 231.Total population of 800 individuals which formed F2 population (9:3:3:1) of a cross between yellow round and green wrinkled. Find the number of plants with yellow and wrinkled seeds 1) 150 2) 400 3) 800 4) 300 232.The recombinant phenotypic ratio in F2 obtained from parental cross having genotypes TTRR x ttrr will be 1) 9:3:3:1 2) 3:1 3) 1:2:1 4) 3:3 233.In a cross between AABB x aabb, the ratio of genotypes in F2 generation between AABB, AaBB, Aabb, aabb would be 1) 2 : 1 : 1 : 2 2) 1 : 2 : 1 : 2 3) 1 : 2 : 2 : 1 4) 1 : 2 : 2 : 4 NARAYANAGROUP UNIT - III :GENETICS SR.BOTANY EAMCET - VOL - I Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION 234.Dominant genes for tallness is T and for yellow colour is Y. A plant with heterozygous for both traits is selfed. Then the ratio of pure homozygous dwarf and green offspring would be 1) 1/4 2) 2/3 3) 3/16 4) 1 /16 235.Experimental verification of the chromosome theory of inheritance was given by 1) Sutton & Boveri 2) Alfred Sturtevant 3) Thomas Hunt Morgan 4) Hugo de Vries 236.In Mendel’s dihybrid cross, percentage of genotypes obtained for the character yellow in heterozygous condition is 1) 25 2) 50 3) 75 4) 6.25 237.There are three genes a, b, c. Percentage of crossing over between a & b is 20, b & c is 28 and a & c is 8. Correct sequence of genes on chromosome is 1) a, b, c 2) a, c, b 3) b, a, c 4) b, c, a 238.The exception to Mendel’s law of independent assortment is 1) Linkage 2) Recombination 3) Co-dominance 4) Incomplete dominance 239.In a cross between tall plant with round seeds [ TTRR ] with a dwarf plant with wrinkled seeds [ ttrr ]. The F1 generation consists of tall plants with round seeds. What would be the proportion of dwarf plants with wrinkled seeds in F2 generation 1) Zero 2) 1 / 2 3) 1 / 4 4) 1 / 16 240.In the law of Mendelian genetics, independent assortment of alleles is due to 1)Location of different alleles on same chromosome 2) Location of allelic pairs on a particular part of homologous chromosome 3) Location of allelic pairs on different homologous pairs of chromosomes 4) Both 1 and 2 241.Genetic map is one that 1) Shows stages of cell division 2) Establishes various stages seen in gene evolution 3) Establishes sites of genes on a chromosome 4) Shows distribution of various chromosomes in a cell 242.Two genes situated very close on the chromosome show 1) High crossing over 2) Hardly no crossing over 3) No crossing over 4) Many times crossing over 243.F1 plant is crossed with one of the parents. In the resultant progeny, phenotype is uniform & genotypic ratio is 1 : 1. It is a type of NARAYANAGROUP 1) Reciprocal cross 2) Back cross 3) Test cross 4) Pureline 244.Read the following and identify the wrong statement 1) During Mendel’s investigation, statistical q q analysis & mathematical logic were applied to problems of biology for the 1st time. 2) Mendel selected 14 true breeding pea varieties 3) Mendel was the 1st to conduct hybridization experiments 4) Mendel’s experiments had large sampling size which gave greater credibility to the data collected 245.When a round seeded pea plant is crossed with a wrinkled seeded pea plant, progeny produced were with round seed & wrinkled seeds. Round seeded parent pea plant in this cross is 1) Homozygous 2) Homozygous or Heterozygous 3) Heterozygous 4) Hemizygous 246.A dihybrid plant on self pollination produced 600 plants with 4 types of genotypes. How many seeds will have genotype Yy Rr 1) 50 2) 100 3) 150 4) 200 247.Which one of the following is incorrectly matched in relation to characters studied by Mendel in Pisum 1) Seed characters-2 2) Flower characters-2 3) Vegetative character-1 4) Fruit characters-3 248. An allele is dominant if it is expressed in 1) Both homozygous and heterozygous states 2) Second generation 3) Heterozygous combination only 4) Homozygous combination only 249 Alleles are 1) Genes found on allosomes 2) Pair of genes governing a specific character like height 3) Genes present on same chromosome 4) Genes present on Y chromosome 250.Two individuals with similar external appearance but different genetic make up have the similar 1) Genotype 2) Phenotype 3) Heterozygote 4) Homozygote 251.Genetic recombination is caused by 1)Fertilisation and mitosis 2)Fertilisation and meiosis 3) Mitosis and meiosis 4) Somatic division 252.Pure line is connected with development of 1) Recombination 2) Heterozygosity 3) Homozygosity and self assortment 4) Heterozygosity and linkage 121 UNIT - III :GENETICS Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION 253.If a homozygous dominant red flowered plant is crossed with a homozygous recessive white flowered plant, the offspring would be (according to law of dominance) 1) half red flowered 2) half white flowered 3) all red flowered 4) half pink flowered 254.When two hybrids undergo crossing then percentage of recessive is 1) 25 2) 100 3) 50 4) 75 255. When a heterozygous tall plant is crossed with a homozygous dwarf , then the percentage of recessive is 1) 25 2) 50 3) 100 4) 75 256. If a pure tall pea plant is raised in nutrient deficient media such that it grows to the size of a dwarf plant and is then selfed, the progeny in normal media will be 1) dwarf 2) all tall 3) 50% tall 50% dwarf 4)75% tall and 25% short 257.Which of the following, follows Mendel’s law of segregation 1) Each gamete receives one gene for an allele 2) Genetic material is equally distributed during mitosis 3) Genetic material enters into one gamete only 4) 1, 2and3 258.When parents ‘A’ and ‘B’ were crossed, F2 progeny was produced with three fourth similar features in phenotype of ‘B’ and one fourth possessed contrasting traits. If the traits being considered here are for height with ‘T’ for tall and ‘t’ for short. What will be the possible genotype of ‘A’ and one fourth of F2 1) tt and Tt 2) Tt and tt 3) Tt and Tt 4) tt and tt 259.Monohybrid cross F1 progeny Tt is inbred. What will be the types of F2 genotypes 1) 3 2) 2 3) 4 4) 1 260.A true breeding plant producing red flowers is crossed with a pure plant producing white flowers. Allele for red colour of flower is dominant. After selfing the plants of first filial generation, the proportion of plants producing white flowers in the progeny would be 1) 3/4 2) 1/4 3) 1/3 4) 1/2 261. A farmer planted 200 seeds collected from a single F1 pea plant, which produced 140 tall and 40 short plants in F2 generation. The genotypes of these offsprings are most likely 1) TT and Tt only 2) TT, Tt, tt 3) Tt and tt only 4) TT and tt only 122 SR.BOTANY EAMCET - VOL - I 262.If a cross is made between AaTT and aatt, where ‘A’ stands for red dominant and ‘T’ for tall dominant. What will be the percentage of red tall plants 1) 25% 2) 50% 3) 75% 4) 100% 263.Heterozygous tall and red flowered pea plants were selfed and total 2000 seeds are collected. What is the total number of seeds for both heterozygous traits 1) 250 2) 500 3) 1250 4) 750 264.Total 512 seeds are collected from the cross WwYy WwYy. Find the number of plants produced with first dominant and second recessive trait 1) 288 2) 96 3) 32 4) 320 265.The term genome is used for 1) Diploid set of chromosomes 2) Polyploid set of chromosomes 3) Triploid set of chromosomes 4) Haploid set of chromosomes 266.The principle of independent assortment of characters is proved by 1) The appearance of tall and dwarf plants in F2 population 2) The appearance of yellow and green in the ratio 3) 1 and also the appearance of round and wrinkled seeded plants in the ratio of 3 : 1 3) The appearance of round and wrinkled seeds plants in the F2 population 4) The observation that F1 progeny is tall 267.Which types of gametes does RrYy produce 1) RY, Ry, rY, ry 2) RY, RY, Ry, RY 3) RY, rY, rY, ry 4) RY, Ry, rY, rY 268.In a dihybrid cross, pure homozygous offspring in the F2 progeny will be 1) 1/2 2) 1/4 3) 1/8 4) 1/16 269.If the cell of an organism heterozygous for two pairs of genes represented by Aa, Bb, undergoes meiosis, then the possible genotypic combination of gametes will be 1) AB, aB, Ab, ab 2) AB, ab 3) Aa, Bb 4) Data insufficient 270.Genes ‘A’ and ‘B’ are present in different chromosomes. A female AaBb was crossed with a male AAbb. The genotypes of gametes will be 1) Female AB, Ab, aB, ab; male Ab 2) Female AA, bb, AB, ab; male Ab 3) Female Aa, Bb; male AA, bb 4) Female AB, ab; male AA, bb NARAYANAGROUP UNIT - III :GENETICS SR.BOTANY EAMCET - VOL - I Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION 271. In pea plants round seed is dominant over wrinkled seed. A plant heterozygous for round seeds was crossed with a plant with wrinkled seeds. Which one of the following progenies agrees with expected result 1) 99 round and 300 wrinkled 2) 301 round and 100 wrinkled 3) 305 round and 301 wrinkled 4) 200 round and 100 wrinkled 272.What proportion of the offspring of a cross AABBcc AaBbCc will be completely heterozygous if all genes segregate individually 1) 1/4 2) 1/16 3) 1/2 4) 1/8 273.If a dwarf pea plant was treated with Gibberellic acid, it grew as tall as the pure tall pea plant. If this treated plant is crossed with a pure tall plant then the phenotypic ratio is likely to be 1) all dwarf 2) 50% dwarf 50% tall 3) 75% tall 25% dwarf 4) all tall 274. RR(red) is crossed with rr(white). All the Rr offspring are pink. This is an indication that R gene is 1) Hybrid 2) Recessive 3) Incompletely dominant 4) Mutant 275. In the case of incomplete dominance F2 generation has 1) Genotype ratio 3 : 1 2) Phenotypic ratio 3 : 1 3) Genotypic ratio equal to phenotypic ratio 4) Genotypic ratio is not equal to phenotypic ratio 276. Co - dominance is observed in 1) Pisum sativum 2) Lens culinaris 3) Lathyrus odoratus 4)Oenothera lamarckiana 277. In a cross between a pure tall pea plant with green pod and a pure short plant with yellow pod, how many short plants out of 16 you would expect in F2 generation 1) 3 2) 9 3) 4 4) 1 278.In Mendel’s experiment how many different kinds of seeds are produced from a short plant with wrinkled seeds (ttrr) 1) 9 2) 4 3) 2 4) 1 279.In garden pea, yellow colour of cotyledons is dominant over green and round shape of seed is dominant over wrinkled. When a plant with yellow and round seeds is crossed with a plant having yellow and wrinkled seeds, the progeny showed segregation for all the four characters. The probability of obtaining green round seeds in the progeny of the cross is 1) 1/8 2) 1/4 3) 1/16 4) 3/16 NARAYANAGROUP 280.A true breeding plant producing red flower is crossed with a pure plant producing white flower. Allele for red colour of flower is dominant. After selfing the plants of first filial generation, the proportion of plants producing white flower in the progeny would be 1) 3/4 2) 1/4 3) 1/3 4) 1/2 281.How many types of gametes may be produced by genotype DdEeFf 1) 27 2) 8 3) 3 4) 6 282.How many pairs of contrasting characters in pea seed were chosen by Mendel 1) 2 2) 3 3) 4 4) 7 283.In pea plants, yellow seeds are dominant to green. If a heterozygous yellow seeded plant is crossed with a green seeded plant, what ratio of yellow and green seeded plants would you expect in F1 generation 1) 50 : 50 2) 9 : 1 3) 1 : 3 4) 3 : 1 284.A pea plant parent having violet coloured flowers with unknown genotype was crossed with a plant having white coloured flowers, in the progeny 50% of the flowers were violet and 50% were white.The genotypic constitution in the parent having violet coloured flowers was 1) Homozygous 2) Merozygous 3) Heterozygous 4) Hemizygous 285.A white flowered (rr) Snapdragon was crossed with red coloured (RR). If 120 plants are produced in F2 generation, the result would be 1) 30 red, 60 pink and 30 white 2) 60 red, 30 pink and 30 white 3) 30 red, 30 pink and 60 white 4) 90 red, 0 pink and 30 white 286.Cytological evidence for chromosomal theory of inheritance is found in 1) Prophase 2) Metaphase-I 3) Anaphase-I 4) Telophase-I 287.Heritable variations occur due to 1) asexual reproduction 2) vegetative propagation 3) sexual reproduction 4) 1 and 2 288.Linear arrangement of genes on chromosomes proposed by 1) T.H. Morgan 2) Sutton and Boveri 3) Sturtevant 4) G.J. Mendel 289.Sutton and Boveri proposed parallelism between chromosomes and genes because 1) both are in the nucleus 2) both segregate at the time of gametogenesis 3) both show independent segregation always 4) 1 and 3 123 UNIT - III :GENETICS Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION 290.Separation of genes due to segregation of chromosomes is called 1) cell theory 2) cell lineage 3) chromosomal theory of heredity 4) mutations theory 291.In a grey bodied Drosophila character 'a' has 68.2% parental combination character 'b' has 98.7% parental combination. This indicates 1) 'a' and 'b' genes are at the same place as that of grey body gene 2) 'a' is nearer grey body gene and 'b' is far away 3) 'a' is far away and 'b' is near grey body gene 4) a ,b are equidistantly placed with respect to grey body gene 292.Crossing over occurs during 1) Anaphase-I 2) Diplotene 3) Pachytene 4) Diakinesis 293.When genes are located on 'X' chromosome crossing over does not occur in 1) Male 2) Female 3) 1 and 2 4) 1 or 2 294.Gene position on a chromosome were mapped by 1) G.J. Mendel 2) Bateson 3) Sturtevant 4) G.H. Shall 295.Number of Mendelian recombinants in F2 dihybrid cross is 1) 10 2) 6 3) 9 4) 16 296.Mendel to pea :: T.H. Morgan to 1) Zea 2) Pisum 3) Lathyrus 4) Drosophila 297.Absence of independent segregation or deviation from 9 : 3 : 3 : 1 ratio in F2 indicates 1) Linkage 2) Crossing over 3) Dominance 4) Absence of sexual reproduction 298.When linkage is present which of the following cannot be observed in a dihybrid cross 1) Dominant trait in F1 2) Recessive in F2 characters 3) 1 : 1 : 1 : 1 ratio in test cross 4) Dominant trait in F2 299.Of white (eye colour gene) and yellow (body colour gene) are tightly linked but white and miniature wing genes are loosely held because 1) recombination percentages is lesser in the former but more in the later 2) recombination percentage equal in both of them 3) parental combinations are lesser in the former and more in the later 4) crossing over absent in both of them. 124 SR.BOTANY EAMCET - VOL - I 300.Which of the following may not apply when the gene controlling two different traits are located on the same chromosome 1) Law of segregation 2) Incomplete dominance 3) Law of dominance 4) Law of independent assortment 301.How many linkage group are there in nucleoid of bacteria 1) One 2) Two 3) Four 4) None 302.If distance between gene on chromosome is more, then gene shows 1) Weak linkage 2) Strong linkage 3) Less crossing 4) Both1 and 3 303.The number of linkage groups in a cell having 10 pairs of chromosomes are 1) 5 2) 10 3) 15 4) 20 304.Complete linkage is found in 1) Birds 2) Snakes 3) Female Drosophila 4) Male Drosophila 305.A phenomenon which works opposite to the linkage is 1) Independent assortment 2) Crossing over 3) Segregation 4) Mutation 306.Which of the following will not result in variations among siblings 1) Independent assortment 2) Crossing over 3) Linkage 4) Mutation 307.Number of linkage groups in a species equals to number of chromosomes in a 1) Spore mother cell 2) gamete 3) zygote 4) sporophyte cell 308.The position of a gene on a given chromosome is 1) Allele 2) Gene locus 3) Linkage 4) Chaismata 309.How many types of gametes will be produced from a microspore mother cell with Bb and Ll genotype when there is 100% linkage between the characters denoted by 'B' and 'L' genes 1) 1 2) 2 3) 4 4) 6 310.Two genes R and Y are located very close on chromosome linkage map of a maize plant. When RRyy and rryy genotypes are hybridized. Then the F2 segregation will show 1) higher number of recombination types 2) segregation in the expected 9 : 3 : 3 : 1 ratio 3) segregation in 3 : 1 ratio 4) higher number of parental types 311.Find odd one out with reference to 100% linkage 1) 100% parental combination in F2 2) F2 phenotypic ratio 3 : 1 3) Dihybrid test cross ratio 1 : 1 4) Linked genes tend to separate frequently NARAYANAGROUP UNIT - III :GENETICS SR.BOTANY EAMCET - VOL - I Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION 312.In what ratio the parental phenotypes will appear in F2 generation of dihybrid cross 1) 3/16 : 3/16 2) 4/16 : 4/16 3) 9/16 : 1/16 4) 12/16 : 4/16 313.On which characters the Mendel's dihybrid experiment was based 1) Green seed coat, round seed x yellow seed coat, wrinkled seed 2) Tall plant, red flower x dwarf plant, white flower 3) Yellow cotyledons, round seed x green cotyledons, wrinkled seed 4) Tall plant, yellow flower x dwarf plant, pink flower 314.Independent assortment means 1) separation of characters of one parent 2) non-separation of characters of one parent 3) combination of parental characters 4) separation of parental characters 315.Mendel’s law of independent assortment 1) will not apply to two genes on the same choromosome 2) will apply only if two genes are on the same choromosome 3) will apply to all genes 4) has now been completely disproved 316.If it is imagined in pea plants that genes for controlling seed coat colour and shape are present on the same chromosome very closely; performing dihybrid experiments with these characters Mendel couldn’t have been able to arrive at the idea of 1) independent assortment 2) dominance 3) segregation 4) incomplete dominance 317.From a cross PPCC ppCC following genotypic ratio will be obtained in F1 generation 1) 1 PpCC: 3ppCC 2) 3 PpCC:1 ppCC 3) all PpCC: No ppCC 4) 1 PpCC:1 ppCC 318.Which of the following explains, how progeny can possess the combinations of traits that none of the parent possessed 1) Chromosome theory 2) Polygenic inheritance 3) Law of segregation 4) Law of independent assortment 319.Who observed that the behaviour of chromosomes at meiosis can serve as the cellular basis of both segregation and independent assortment 1) Sutton and Boveri 2) Banden and Boveri 3) W. Flemming 4) Boveri and Braue 320.A red and tall dominant character hybrid plant is crossed with recessive white dwarf plant (RrTt rrtt). What will be the ratio of respective four combinations : red tall, red dwarf, white tall and white dwarf plants in the NARAYANAGROUP next generation 1) 9 : 3 : 3 : 1 3) 9 : 3 : 4 : 0 1) 15 : 1 : 0 : 0 4) 4 : 4 : 4 : 4 EXERCISE-II (Sharpen Your Reflexes) 321.Test plant used by Mendel is (1) a member of (2) family in it yellow seed coat is dominant because crossing of pure yellow and pure green gives 100% (3). 1,2,3 respectively are 1) Pea, Fabaceae, Yellow 2) Lathyrus, Fabaceae, Long pollen 3) Drosophila, Diptera - Vestigial wing 4) Antirrhinum, Verbinaceae, Yellow 322.Taking the symbols on certain chromosomes present in lentils such as for spotted - CSCS , dotted CDCDand spotted & dotted CSCD, find out the ratios obtained in F2 generation and identify the dominance respectively I. Spotted, dotted & spotted, dotted are in ratio of 1 : 1 : 1 respectively and is incomplete dominance. II. Spotted, Spotted & dotted, Dotted are in ratio of 1 : 2 : 1 respectively and is co-dominance. III. Dotted, spotted, spotted & dotted are in ratio of 1 : 1 : 2 respectively and is incomplete dominance. IV. Spotted, dotted, spotted & dotted are in ratio of 1 : 1 : 2 respectively and is incomplete dominance. 1) 1 & II are correct 2) Except II all are incorrect 3) I, II, III are correct 4) IV alone correct. 323.Study the following statements I) A homozygous tall plant is crossed with homozygous dwarf (TT tt), produces 100% tall progeny II) A heterozygous tall selfed, produces tall and dwarf progeny successively 75%, 25% III) A heterozygous tall crossed with homozygous dwarf, tall and dwarf are produced in 1 : 1. IV) A heterozygous tall crossed with homozygous tall, produces tall and dwarf in 100 : 0 ratio. 1) I and II are correct 2) II and III are correct 3) I, II, III, IV are correct 4) I and IV are correct 324.When YYRR is crossed with yyrr the genotype of F1 (1). Number of types of gametes in F1 (2). Number of phenotypes in F2 (3). 1) yyRR - 4 - 9 2) yyRR - 4 - 9 3) YyRr - 4 - 4 4) YyRr - 4- 10 125 UNIT - III :GENETICS Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION 325.Find the correct ideas of homozygous plants A) They are formed by repeated self fertilization B) They have two copies of same gene. C) They form two types of gametes each containing different copy of the same gene. D) They are formed by cross fertilization. 1) A, B, D are correct 2) A and D only correct 3) A and B are only correct 4) A, B, C are correct 326.The examples for co-dominance are A) ABO blood grouping in human beings B) Seed coat pattern in lentil plants C) Inheritance of flower colour in Antirrhinum 1) B only 2) A only 3) A & B only 4) A,B&C 327.The progeny obtained by crossing pure/true breeding plants is A) a hybrid B) inbred C) Heterozygous D) Homozygous The correct pair is 1)A and B 2)C and D 3)A and C 4)A and D 328.Find the combination of dominant characters studied by Mendel A) Round shaped yellow seeds B) Wrinkled seeds axial flowers C) Round shaped green seeds D) Axial flowers on long stems 1)A and D 2)A and B 3)C and D 4)A and C 329.Mendel in his experiments conducted A) Natural pollination B) Artificial pollination C) Vegetative propagation D) Apomixes 1)A and C 2)A and D 3)A and B 4)B and D 330.When same path of characters are passed to several generations the possible combination of reasons I) Homozygosity II) Vegetative propagation III) Linkage of genes (100%) IV) Crossing over 1) I and II only 2) I, II, III only 3) II and III only 4) IV only 331.Linkage decreases the frequency of I) Hybrid II) Recessive allele III) Dominant allele IV) Recombinants 1) I and II 2) I and IV 3) I and III 4) II and IV 332.Both genotypic phenotypic ratio of progeny is 1:2:1 in case of I. Incomplete dominance II. Co-dominance III. Monohybrid back cross IV. Monohybrid test cross 1) I & III 2) All 3) I, III & III 4) I & II 126 SR.BOTANY EAMCET - VOL - I EXERCISE - III Think Twice Before you choose (‘Assertion’ and ‘Reason’ type Questions) 1) A is correct and R is explanation to A. 2) A is correct and R is not an explanation to A 3) A is true and R is wrong. 4) A is wrong and R is true. 333.(A) : Test cross is conducted to know the genotype of F1 individual. (R) : In a test cross dominant phenotypic organism is crossed with heterozygous one. 334.(A) :Mendel selected garden pea plant for his hybridization experiments (R) :Morphology of useful parts in garden pea are seeds 335.(A) : A cross between pure-breeding spotted Lentil and pure-breeding dotted Lentils produce heterozygotes that are both spotted and dotted. (R) : The (R) for this heterozygosity is that the spotted allele and dotted allele are co-dominant. 336.(A): If a single gene is related to more than one character, that single gene product may produce more than one effect. (R): Production of more than one character by one single gene is called polymorphism. 337.(A): Chromosomal theory of inheritance was proposed by Sutton and Boveri. (R): The knowledge of chromosomal segregation when united with Mendelian principles it is called chromosomal theory of inheritance. 338.(A): The physical association of genes on a chromosome is called Linkage. (R): The generation of non-parental gene combinations is described as recombination 339.(A): The frequency of recombination between gene pairs on the same chromosome was used as a measure of the distance between genes on the chromosome. (R): Several dihybrid crosses in Drosophila were carried out by Morgan. 340.(A): The alteration in chromosomes by deletion or duplication of a segment of DNA results in chromosomal aberrations. (R): Chromosomal aberrations are commonly observed in cancer cells. 341.(A): Sickle cell anemia is a classical example for point mutation. (R): The change in a single base pair of DNA is called point mutation. NARAYANAGROUP UNIT - III :GENETICS SR.BOTANY EAMCET - VOL - I Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION 342.(A): Ultra violet radiation is a mutagen. (R):He was lucky in selecting seven characters in (R) : U.V radiation can cause mutations in wild pea. organisms. 355.(A) : Mutations generate a large amount of variations 343.(A): In dihybrid cross conducted by Mendel, the in a population. pairs of factors are located in two pairs of (R) : A breeder can select all the variations caused homologous chromosomes. by mutations. (R) :Each homologous pair of chromosomes 356.(A) : Linkage leads to more parental types. bears two pairs of factors for same gene. (R) : Linkage reduces the number of types of 344.(A): Hybrids produced by hybridization process variable gametes. always carry desired genes only. 357.(A) : Mendel did not recognise the linkage (R): Hybridization process involves crossing two phenomenon in his experiments. plants with desirable characters. (R) : The factors he considered were located on 345.(A): The linked genes tend to get inherited together. different chromosomes. (R): Crossing over never occurs between two homologous chromosomes of a bivalent at the sites EXERCISE - IV in between two weak linked genes. 346.(A) : Pea plant shows stable trait inheritance and (Simple matching Questions) expression for several generations 358.Correct match the following (R) : Pea plant is a self pollinated member of List – I List–II Solanaceae. In Monohybrid cross 347.(A) : In Mendel’s monohybrid cross F1 plant A) Phenotypic ratio of F2 progeny I) TT produce 2 types of female gametes and 2 types of B) Genotypic ratio of F2 progeny II) TT, tt male gametes C) Genotypes of Parents III) 3 : 1 (R) : F1 Plants of normal monohybrid cross are in D) Genotype of F1 hybrid IV) Tt heterozygous (Tt) condition. V) 1 : 2 : 1 348.(A) : Linkage is inversely proportional to distance A B C D A B C D between genes on a chromosome. 1) II V III IV 2) III IV II V (R) : Closed genes linked strongly where as farther 3) III V II IV 4) IV II V III genes linked weakly. 349.(A) : In Mendel’s monohybrid cross, the probability 359. Match the following List – I List – II of obtaining dwarf plants in F1 is zero. A) Genetic make up of I) Contrasting traits (R) : F1 individuals of monohybrid cross show an individual alleles for tallness only. B) The alternative forms II) Allelomorphs 350.(A) : In co-dominance, the phenotypic and genotypic of a Character ratios are same. C) The two alternative III) Genotype (R) : Heterozygotes can be distinguished from forms of a gene homozygotes. D) Pairs of contrasting IV) Alleles 351.(A) : Loss or gain of a segment of DNA results in characters alternation in chromosomes. (R) : One DNA helix runs continuously from one The correct match is 1) A-II, B-I, C-IV, D-III end to the other in each chromatid in a highly super 2) A-II, B-IV, C-I, D-III coiled form . 3) A-III, B-I, C-IV, D-II 352.(A): Mendel observed recombinants along with 4) A-III, B-IV, C-I, D-II parental combinations during dihybrid experiment. (R): Characters studied by Mendel for his each 360.Study the following columns and identify the correct match dihybrid cross experiment were on a separate Column – I Column – II chromosomes but not on same chromosome. A Monohybrid cross p. T and t 353.(A) : All test cross are back crosses. B Test cross q. TT (R) :A back cross in which recessive parent is C Alleles r. TT X tt involved is test cross. D Homozygous tall s. tt 354.(A):Mendel gave postulates like “principles of t. Tt X tt segregation and principles of independent A B C D A B C D assortment” after studying seven pairs of contrasting 1) r p t c 2) r t p q traits in garden pea. 3) r t s q 4) t r q s NARAYANAGROUP 127 UNIT - III :GENETICS Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION SR.BOTANY EAMCET - VOL - I 361.Study the following and identify the correct dihybrid cross C) 5 : 3 match. III) Dihybrid phenotypic ratio D) 1 : 3 : 1 Character of pea Recessive trait IV) Dihybrid test cross ratio E) 1 : 2 : 1 A. Pod shape I. Wrinkled The correct combination is B. Pod colour II. Yellow 1) I-E, II-C, III-D, IV-A C. Seed shape III. Constricted 2) I-B, II-C, III-A, IV-D D. Seed colour IV. Green 3) I-E, II-C, III-B, IV-A V. Grey 4) I-A, II-B, III-C, IV-D 1) A - IV, B - V, C - II, D - I 365. Column - I Column - II 2) A - III, B - II, C - I, D - IV Cross Phenotypic ratio 3) A - II, B - III, C - I, D - IV I) Rr Rr A) ! : 1 : 1 : 1 4) A - I, B - II, C - IV, D - III II) Rr rr B) 9 : 3 : 3 : 1 362.Match the following and find the correct III) RrYy RrYy C) 1 : 1 combination. IV) RrYy rryy D) 3 : 1 I) Homozygous A) Forms more than one type The correct combination is of gametes 1) I-D, II-C, III-B, IV-A II) Phenotype B) Appears in F1 of a cross 2) I-A, II-B, III-C, IV-D 3) I-A, II-D, III-B, IV-C between pure parents. 4) I-B, II-C, III-D, IV-A III) Dominant C) Physical appearance of a 366. List - I List - II character trait A) T.H. Morgan I)Chromosomal maps IV) Heterozygous D) Arises by self fertilization 1) I-D, II-C, III-B, IV-A B) G.J. Mendel II) Linkage C) Sturtevant III) Checker board 2) I-C, II-D, III-A, IV-B D) Reginald C Punnett IV) Laws of heredity 3) I-A, II-B, III-C, IV-D The correct combination is 4) I-B, II-C, III-A, IV-D 1) A-II, B-IV, C-I, D-III 363.Match the following and find the correct combination 2) A-III, B-II, C-IV, D-I Character Phenotype 3) A-II, B-III, C-I, D-IV I) Flower position A) Axil 4) A-II, B-I, C-III, D-IV II) Colour of flower B) Violet 367.List - I List - II III) Seed shape C) Round I) G.J. Mendel A) Chromosomal theory of inheritance IV) Pod colour D) Green II) Hugo de Vries B) Linkage in Drosophila 1) I-A, II-C, III-D, IV-B III) T.H. Morgan C) Mutations 2) I-C, II-A, III-D, IV-B 3) I-A, II-B, III-C, IV-D IV) Sutton and Boveri D) Law of dominance The correct combination is 4) 1-D, II-B, III-C, IV-A 1) I-D, II-C, III-B, IV-A 364. List - I List - II 2) I-A, II-B, III-C, IV-D I) Incomplete dominance A) 1 : 1 : 1 : 1 3) I-B, II-C, III-D, IV-A genotypic ratio in F2 of 4) I-D, II-A, III-B, IV-C dog flowers II) Ratio of parental types B) 9 : 3 : 3 : 1 to recombinant types in the phenotypes of F2 128 NARAYANAGROUP UNIT - III :GENETICS SR.BOTANY EAMCET - VOL - I Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION EXERCISE - V 368. Character Dominant Trait Recessive Trait I. Shape of the seed Round Wrinkled II. Colour of the pod Green Yellow III.Position of the flower Terminal Axial IV Colour of the seed Yellow Green 1) I, II and IV only 2) I and II only 3) I and IV only 4) I and III only 369. Which of the following combinations has all the dominant characters with reference to contrasting traits of Garden pea? Colour of Shape of Colour of Position of Colour of unripe pod Seed Cotyledon flowers Flower 1) Yellow Round Green Terminal White 2) White Wrinkled Yellow Axial Green 3) Green Round Yellow Axial Violet 4) Green wrinkled Yellow Terminal White 370.Study the following Phenotypes No.in F2 progeny Number of Genotypes for different traits I) Yellow, round 9 homozygous for yellow = 4 II) Yellow, wrinkled 3 homozygous for wrinkled = 0 III) Green, round 3 homozygous for round = 1 IV) Green, wrinkled 1 homozygous for green = 3 The correct combination is 1) I, II, IV 2) II, IV 3) I, III 4) III, IV 371.Study the following I) Hybridisation Recombination and gametes II) Mutation Variations Genetic integrity III) Linkage Stability of genes New varieties IV) Crossing over Evolution New species The correct combination is 1) I, II 2) I, IV 3) II, III 4) III, IV 372.Study the following Phenotype Genotype Nature of the trait I) Homozygous tall TT Dominant II) Heterozygous tall Tt Recessive III) Homozygous dwarf tt Recessive IV) F1 hybrid TT Dominant The correct combination is 1) II, III 2) I, IV 3) II, IV 4) I, III 373.Study the following I) Garden pea Law of dominance Mendel II) Lentil Co-dominance Flower colour III) Snapdragon Incomplete dominance Seed coat patterns IV) Fruit fly Linkage Morgan The wrong combination is 1) II, IV 2) II, III 3) I, IV 4) III, IV NARAYANAGROUP 129 UNIT - III :GENETICS Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION 374. 375. 376. 377. 378. SR.BOTANY EAMCET - VOL - I Study the following Genotype Phenotype Probability I) RRyy Round, green 1/16 II) RrYy Round, yellow 4/16 III) RRYy Wrinkled, yellow 2/16 IV) rryy Wrinkled, yellow 1/16 The correct combination is 1) I, II, IV 2) II, III, IV 3) I, II, III Study the following Type of cross Genotype Genotypic ratio I) Monohybrid cross TT x tt 1:2:1 II) Back cross Tt x TT 3:1 III) Dihybrid cross RRYY x rryy 1:1:1:1 IV) Test cross Tt x tt 1:1 The correct combination is 1) I, II, III 2) I, IV 3) II, III, IV Study the following I) Chromosome Cell division Two genomes II) DNA High molecular weight Stable III) Gene Segment of DNA Contrasting traits IV) Allele Alternate forms of same gene Unit of inheritance The wrong combination is 1) I, II 2) II, III 3) I, III Study the following combinations Genotypes Numbers Probability I) YYRR 1 1/4 x 1/4 II) YyRR 2 3/4 x 1/4 III) Yyrr 2 1/4 x 3/4 IV) YyRr 4 1/2 x 1/2 The correct combination is 1) I, IV 2) II, III 3) III, IV Study the following I) Dihybrid test cross 1:1:1:1 Genotypic ratio II) Co-dominance 1:2:1 Phenotypic ratio III) Incomplete dominance 1:1 F1 progeny IV) Monohybrid cross 3:1 F2 genotypic ratio The correct combination is 1) I, II 2) III, IV 3) II, IV 4) I, III 4) I, III 4) III, IV 4) I, III 4) II, III 3) Pasteur - Inheritance of acquired characters 4) de Vries - Natural selection EXERCISE - VI 380.In Pisum sativum there are 14 chromosomes. How many pairs with different chromosomal (QUESTION FROM PREVIOUS composition can be prepared? [BHU 2005] MEDICAL EXAMINATIONS ) 1) 214 2)27 3) 7 4)14 379.Which one of the following scientist’s name is 381.Source of Mendelian recombination is correctly matched with the theory put forth by [D.P.M.T. 2001] him [CBSE-2008] 1) Linkage 2) Independent assortment 1) Mendel - Theory of pangenesis 3) Mutations 4) Dominant traits 2) Weiseman - Theory of continuity of germplasm 130 NARAYANAGROUP UNIT - III :GENETICS SR.BOTANY EAMCET - VOL - I Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION 382.A recessive trait in Garden Pea is [Karnataka 1999] 1) Wrinkled seeds 2) Tall stem 3) Round seeds 4) Coloured seed coat 383.Which is correct about traits chosen by Mendel [C.B.S.E. 2000] 1) Terminal pod is dominant 2) Constricted pod is dominant 3) Green coloured pod is dominant 4) Tall plants are recessive 384.Which one is not a dominant trait amongst seven Pea traits chosen by Mendel [ManipaI 2000] 1) Flower Colour–Purple 2) Pod Colour–Yellow 3) Shape of Seed–Round 4) Flower–Axial 385.Main reason for success of Mendel was [B.V. 2000] 1) He employed statistical analysis 2) He performed statistical experiments 3) His choice of Pisum sativum 4) He was the first to work on a plant 386.Correct reason for Mendel’s success was [B.H.U. 2001] 1) He repeated each experiment several times 2) Traits chosen by him had genes far apart so that linkage was absent 3) He kept record of all experiments 4) He used statistical techniques 387.In Pea, wrinkling of seeds is due to starch because of the absence of enzyme [C.B.S.E. 2001] 1) Amylase 2) Invertase 3) Branching enzyme 4) Diastase 388.Who amongst the following scientists rediscovered Mendel's work ? [M.P.P.M.T. 2002] 1) T.H. Morgan 2) W. Bateson 3) E. Strasburger 4) Von Tschermak 389.Emasculation is related to [Manipal 2002] 1) Pure line 2) Homozygocity 3) Clonal selection 4) Hybridisation 390.Which one of the following traits of Garden Pea studied by Mendel was a recessive feature [C.B.S.E. 2002] 1) Axial flower position 2) Green seed colour 3) Green pod colour 4) Round seed shape 391.Which trait was not incorporated by Mendel for his experiments? [RPMT 2005] 1) Colour of Pea seed 2) Colour of Pea flower 3) Colour of Pea Plant 4) Colour of Pea pod 392.The phenotypic ratio of a monohybrid cross is [MHCET 2003] NARAYANAGROUP 1) 9 : 3 : 3 : 1 2) 1 : 2 : 1 3) 3 : 1 4) 1 : 2 : 3 393. In a cross 50% individuals were tall and 50% were dwarf. So the cross was between [MHCET 2005] 1) Tt tt 2) Tt TT 3) TT tt 4) Tt Tt 394.Crosses between F1 offsprings and either of their parents are known as[AFMC 2006] 1) reciprocal cross 2) back cross 3) dihybrid cross 4) polyhybrid cross 395.Hetrozygous purple flower is crossed with recessive white flower. The progeny has the ratio [DPMT 2003] 1) all purple 2)all white 3) 50% purple and 50% white 4) 75% purple and 25% white 396.The crossing of an organism with a double (homozygous) recessive in order to determine whether it is homozygous or heteorzygous for a character under consideration is known as [AMU 1998, KEREALA PMT 2001,2002, GGSIPU 2003] 1) back cross 2) test cross 3) reciprocal cross 4) dihybrid cross 397. A cross between hybrid and a recessive parent (Tt tt) gives a ratio of [Kerala PMT 2004] 1) 1 : 1 2) 2 : 1 3) 3 : 1 4) 4 : 1 398. Test cross involves [AIPMT 2006] 1) crossing between two genotypes with dominant trait 2) crossing between two genotypes with recessive trait 3) crossing between two F1 hybrids 4) crossing the F1 hybrid with a double recessive genotype 399 .A cross between the heterozygous F1 hybrid and the double recessive homozygous parent is known as [KCET 2007] 1) heterosis 2) test cross 3) reciprocal cross 4) inbreeding 400.Identify the wrong statement (EAMCET 2012) 1) The probability of homozygous dwarf progeny formed in a cross TT TT is zero. 2) The heterozygous tall progeny formed in a cross TT Tt is 0.5. 3) The homozygous dwarf formed in TT Tt is 0.75. 4) The homozygous tall progeny formed in a cross involving TT TT is 1.0 131 UNIT - III :GENETICS Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION 401.In dihybrid cross the F1 heterozygous plants are self fertilized to produce an F2 generation and if offsprings are computed in Punnett square the phenotypic F2 ratio as per Mendel’ss independent assortment will yield [AFMC 2000, Orissa JEE 2003] 1) 9 : 7 2) 9 : 3 : 3 : 1 3) 9 : 6 : 1 4) 12 : 3 : 1 402.In a cross between individuals with genotypes TtRr, if the resulting number of offsprings is 16, identify the number of genotypes with TtRr and TtRR among them [EAMCET 2003] 1) 1 and 2 2) 2 and 3 3) 3 and 1 4) 4 and 2 403.The product of cross between pure tall, green seeds and pure dwarf, yellow seeds is crossed with pure dwarf and green seeds then number of phenotype produced are [BVP Pune 2003] 1) 2 2) 6 3) 4 4) 1 404.The ratio of 1 : 1 : 1 : 1 is obtained from a cross between the parents [Kerala PMT 2003] 1) RRYY rryy 2) RRYy rrYy 3) RrYY Rryy 4) RrYy rryy 405.Mendelian recombination is due to [DYPatil Pune2004] 1) Independent assortment 2) segregation 3) Mutation 4) Linkage 406.What will be ratio of combination of parental to non-parental in F2 generation where F1 is produced by pure breeding yellow round seeds crossed with green wrinkled seed? [DY Patil Pune 2004] 1) 12 : 4 2) 9 : 1 3) 5 : 3 4) 16 : 1 407.Number of male gametes having both dominant genes for YYRr per 1000 is [DY Patil Pune 2004] 1) 500 2) 250 3) 750 4) 1000 408.The ratio of homozygous dominant and homozygous recessive in dihybrid cross is [BVP Pune 2004] 1) 1 : 16 2) 1 : 8 3) 16 : 1 4) 1 : 1 409.A dihybrid for qualitative trait is crossed with homozygous recessive individual of its type, the phenotypic ratio is [Orissa JEE 2005] 1) 1 : 2 : 1 2) 3 : 1 3) 1 : 1 : 1 : 1 4) 9 : 3 : 3 : 1 410.The percentage of yr gametes in YyRr is [Maharashtra CET 2005] 1) 25% 2) 50% 3) 75% 4) 100% 411. In order to find out the different types of gametes produced by a pea plant having the 132 SR.BOTANY EAMCET - VOL - I genotype AaBb, it should be crossed to a plant with the genotype [AIPMT 2005] 1) aaBB 2) AaBb 3) AABB 4) aabb 412.Which genotype represents a true hybrid condition? [CPMT 2005] 1) TTrr 2) TtRr 3) TTRr 4) ttrr 413.In progeny of dihybrid cross in F2 generation, how many plants are homozygous recessive? [Harayana PMT 2005] 1) One 2) two 3) Three 4) Four. 414.A dihybrid plant on self pollination, produced 400 plants with 4 types of genotype. How many seeds will have genotype TtRr? [CPMT 2006] 1) 200 2) 100 3) 50 4) 150 415.Cross between plants having YYRR and yyrr will yield [Harayana PMT 2006] 1) yellow and round seeds 2) yellow and wrinkled seeds 3) green’s round seeds 4) green and wrinkled seeds 416.The ratio of F2 phenotype generation in Mendel’s dihybrid cross between yellow and green seeds was [DY Patil 2006] 1) 3 : 1 2) 2 : 1 3) 1 : 1 4) 12 : 4 417.A double homozygous tall pea plant with green cotyledons is crossed with pure dwarf plant with yellow cotyledons. The offspring are crossed with pure dwarf plant with green cotyledons. How many different phenotypes will be obtained in this progeny? [DY Patil Pune 2007] 1) 16 2) 2 3) 4 4) 1 418.Dihybrid genotypic testcross ratio is [CMC Vellore 2007] 1) 1 : 12 2) 1 : 1 : 1 : 1 3) 3 : 1 4) 1 : 1 419.If dominant alleles or recessive alleles tend to remain in different plants, then this could be [CMC Vellore 2007] 1) Independent assortment 2) Segregation 3) Dominance4) by chance 420.When a dihybrid cross is fitted into a Punnett square with 16 boxes, the maximum number of different phenotypes available are [Kerala PMT 2008] 1) 8 2) 4 3) 2 4) 16 421.Mendel crossed tall and rounded seeds with short and wrinkled. In F2 generation he saw 1/ 16 were short and wrinkled seeds. What did he conclude from this? [HP PMT 2008] 1) Short and wrinkled show linkages 2) Tall and wrinkled never combine 3) They show independent assortment 4) None of the above NARAYANAGROUP UNIT - III :GENETICS SR.BOTANY EAMCET - VOL - I Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION 422.The number F2 plants found similar to F1 phenotype and genotypes respectively in a total of 128 plants in F2 progeny of a Mendelian dihybrid cross [EAMCET 2011] 1) 70, 30 2) 72, 32 3) 24, 12 4) 40,70 423.In garden pea yellow is dominant over green, round is dominant over wrinkled yellow round is crosses with yellow wrinkled. Progeny shows segregation of all the four types. The probability of green round in this crosses [EAMCET 2009] 430.Any change in the structure of the chromosome will change the structure of gene. Hence it is true statement. 424.How many different types of gametes can be formed by F1 progeny, resulting from the following cross: AA BB CC aa bb cc [AIIMS 2004] 1) 3 2) 8 3) 27 4) 64 425.A self-fertilizing trihybrid plant forms [APMT 2004] 1) 8 different gametes and 64 different zygotes 2) 4 different gametes and 16 different zygotes 3) 8 different gametes and 16 different zygotes 4) 8 different gametes and 32 different zygotes 426.How many different kinds of gametes will be produced by a plant having the genotype AABbCC? [APMT 2006] 1) Two 2) Three 3) Four 4) Nine 427.A dwarf pea plant treated with gibberellic acid, becomes tall, then crossed with pure homozygous tall pea plants, then what will be the phenotypic ratio of tall pea plants in F1 progeny? [BVP Pune 2007] 1) 100% dwarf plants 2) 50% tall plants 3) 100% tall plants4) all tall pea plants. 428.The number of genotypes produced when individual of genotype YyRrTt are cross with each other? [MGIMS Wardha2006; DYPatil Pune 2004] 1) 4 2) 64 3) 28 4) 27 429.A homozygous sweet pea plant with blue flowers (RR) and long pollen ( R0 R0 is crossed with a homozygous plant having red flowers (rr) and round pollen r0 r0 . The resultant hybrid is test crossed. Which of the following genotype does not appear in its progeny [EAMCET 2009] 1) Rrrr0 2) RrR0 r0 3) Rrr0 r0 4) rrR0 r0 NARAYANAGROUP 430.All genes located on the same chromosome [PMT 2007] 1) Form different groups depending upon their relative distance. 2) Form one linkage groups, 3) will not form any linkage group. 4) form interactive group. 431.Distance between the genes and percentage of recombination shows [PMT 2008] 1) direct relationship 2) an inverse relationship 3) a parallel relationship 4) no relationship 432.The first attempt to show linkage in plants was done on [PMT 2002] 1) Pisum sativum 2)Lathyrus odoratus 3) Oenothera lamarkiana 4) Zea mays 433.When two genes are situated very close to each other in a chromosome then [CPMT 2007] 1) the percentage of crossing over between them is very high 2) hardly any crossing over detected 3) no crossing over takes place between them. 4) no double cross over can take place between them. 434.Bacteria and blue green algae contain [AIIMS 2003] 1) one linkage group 2) two linkage groups 3) many linkage groups 4) no linkage group. 435.A cross between two tall garden pea plants produced all tall plants. The possible genotypes of the parents are [EAMCET -2014] I) TT,TT II) TT,Tt III) Tt, tt IV) Tt, Tt The correct answer is 1) III, IV 2) I, IV 3) I, II 4) II, III 436.Tall (T) is completely dominant over dwarf (t). Red flower colour (R) is incompletely dominant over white (r), the heterozygote being pink. Plant having genotype of Tt Rr is self pollinated. What would be the proportion of plants with dwarf and pink characters in its progeny ? [EAMCET-2014] 1) 2 16 2) 1 `` 16 3) 9 16 4) 3 16 437.Assume that blue flower of a plant is dominant character over the white. When a blue flowered plant is crossed with white flowered plant, the progeny showed 50% of plants with blue flowers and 50% of plants with white flowers. The genotypes of blue and white parents respectively are [EM -2013] 1) BB,bb 2) Bb,bb 3) bb,bb 4) BB,Bb 133 UNIT - III :GENETICS Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION EXERCISE - VII TRUE/ FALSE STATEMENTS 438.Mendel’s genes are now a days factor’s 439.The entire body of molecular biology was a consequent development with major contribution of Krebs, Calvin, Crick and Mendel 440.One of the causes of variation was hidden in a sexual reproduction 441.Natural selection and breeding are the key process in the development of Sahiwal Cows in Punjab and Ongole bulls in A.P. 442.Mendelian general rules of inheritance were not substantiated ideas 443.Pea plant self fertilized inconveniently 444.According to Mendelian rules, F1 is always similar to one of the parent 445.Emasculation is essential for obtaining F 2generation in Mendelian monohybrid cross 446.Mendel was an Australian monk 447.The phenotype height is represented with the genotypes TT or Tt or tt 448.The genotype of F2 dwarf plants was homozygous 459.Mendel found that dwarf plants of F2 continued to generate dwarf plants in F3 and F4 450.Checker Board developed by British chemist Punnett 451.Recessive trait may not be in heterozygous 452.During formation of gametes, the paired unit factors separate randomly with equal probability due to meiosis 453.Generally gametes are pure for their factor they posses 454.F1 hybrid is crossed with parental type having dominant trait in homozygous condition, the no. of recombinant individuals is 50% 455.Pleiotropy means a single character influenced by many genes 456.Mutation useful in crop improvement 457.Alternative form a character is called allele 458.In co-dominance the phenotypic ratio of F2 progeny is 3 : 1. 459.Drosophila is morphologically easily distinguishable 460.According to concept of linkage, two alleles of a gene located on same chromosome. 461.Mendel proposed his law of independent assortment based on results on dihybrid cross. 462.Alleles of same gene present on similar locations of homologous chromosomes. 463.The probability of double homozygous individuals in F2 generation Mendel dihybrid cross is 1/4. 134 SR.BOTANY EAMCET - VOL - I 464.Externally it is possible to distinguish between the plants with the genotypes TT and Tt. 465.In a test cross, dominant phenotype is crossed with recessive parent instead of self fertilization. 466.Genes can never be mutated 467.Dominance is not an autonomous feature of a gene. 468.Linkage is inversely proportional to distance between the genes of the same chromosome. 469.Mutations first discovered by Hugo de Vries 470.The term linkage coined by T.H. Morgan. 471.RBC that determining ABO blood group and seed coat pattern example for incomplete dominance 472.In dihybrid cross of Morgan, the proportion of parental gene combination was much higher than the non parental type 473.Chromosomal theory of inheritance proposed by Watson and Crick. 474.Mendel dihybrid test cross ratio is 1 : 1 : 1 : 1 475.Co - dominance is seen in Snapdragon. 476.Generally gametes are pure for the factors they possess 477.Number of monohybrid traits in typical dihybrid is 8 478.Several dihybrid crosses in Drosophila were carried out by Sutton and Boveri 479.Number of phenotype in monohybrid test cross is 2 and genotype also 2. 480.Number of double dominant individuals in Mendel dihybrid F2 progeny is 1. 481.Chromosomal aberrations are commonly observed in cancer cells. 482.Factors are discrete which controls characters. 483.Unit factors occurs in paired condition. 484.Sickle cell anemia is a classical example for point mutation 485.The change in a single base pair of DNA is called point mutation 486.Deletions and insertions of base pairs of DNA cause frame shift mutations. 487.UV radiations is an example of chemical mutagen 488.Desirable mutations helps in crop improvement 489.Any change in the structure of the chromosome will change the structure of gene. 490.Number types of gametes produced from Tt genotype is two 491.Sutton and Boveri noted parallelism between behaviour of chromosomes and genes. 492.Number of Homozygous tall individuals in F 2 generation of monohybrid cross is 1. NARAYANAGROUP UNIT - III :GENETICS SR.BOTANY EAMCET - VOL - I Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION KEY PRACTICE TEST-I 1) 4 7) 3 13) 4 2)1 8)4 14) 2 3)4 4) 2 5) 4 9) 2 10) 1 11)1 15) 3 6) 4 12) 4 PRACTICE TEST-II 16) 4 22) 1 28)4 34) 2 17)2 23) 3 29) 2 35) 2 18) 2 19) 1 20) 2 21) 1 24) 3 25) 2 26) 2 27)1 30) 2 31) 4 32) 2 33) 2 36) 4 PRACTICE TEST-III 37)2 43) 1 49)2 55) 2 38)3 44) 4 50)2 56) 1 39) 3 45) 3 51) 2 57) 1 40) 1 41) 4 42) 2 46)1 47)4 48)2 52) 3 53) 4 54) 1 58)1 PRACTICE TEST-IV 59) 3 65)2 60)3 66)2 61)2 67)4 62)3 68)2 63)3 64)2 69) 2 PRACTICE TEST-V 70) 2 76) 2 82) 4 88) 2 71) 3 77) 4 83) 1 72) 1 73) 4 74) 1 75) 1 78) 1 79) 4 80) 4 81) 3 84) 3 85) 4 86) 4 87)4 PRACTICE TEST-VI 89) 4 95) 2 90) 4 96) 3 91) 2 92) 3 93) 3 94) 2 97) 4 98) 1 99) 1 100)4 PRACTICE TEST-VII 101) 1 102) 3 107)4 108) 3 103) 4 104) 4 105) 1 106)4 109) 1 110) 1 QUESTION BANK (EI - EVII) CHECK YOUR MEMORY (E–I) 111)1 117)4 123)4 129)3 135)3 141)2 147)3 153)3 159)2 165)2 171)1 177)4 183)4 189)4 195)2 201)2 207)2 213)3 219)4 225)4 112)2 118)1 124)3 130)2 136)2 142)1 148)2 154)1 160)4 166)2 172)3 178)3 184)4 190)3 196)4 202)3 208)1 214)1 220)1 226)2 NARAYANAGROUP 113)2 119)3 125)4 131)3 137)1 143)3 149)1 155)1 161)2 167)4 173)2 179)3 185)4 191)3 197)2 203)2 209)2 215)2 221)2 227)2 114)4 120)4 126)1 132)1 138)2 144)2 150)2 156)1 162)4 168)2 174)4 180)3 186)2 192)1 198)3 204)2 210)2 216)2 222)2 228)2 115)3 121)3 127)2 133)2 139)2 145)4 151)3 157)4 163)4 169)1 175)1 181)3 187)2 193)4 199)3 205)1 211)4 217)3 223)3 229)4 116)1 122)1 128)2 134)1 140)1 146)3 152)2 158)3 164)2 170)2 176)3 182)4 188)2 194)2 200)4 206)3 212)1 218)4 224)2 230)3 231)1 237)3 243)2 249)2 255)2 261)2 267)1 273)4 279)1 285)1 291)3 297)1 303)2 309)2 315)1 232)4 238)1 244)3 250)2 256)2 262)2 268)2 274)3 280)2 286)3 292)3 298)3 304)3 310)4 316)1 233)3 239)4 245)3 251)2 257)1 263)2 269)1 275)3 281)2 287)3 293)1 299)1 305)2 311)4 317)3 234)4 240)3 246)3 252)3 258)4 264)2 270)1 276)2 282)1 288)1 294)3 300)4 306)3 312)3 318)4 235)3 241)3 247)4 253)3 259)1 265)4 271)3 277)3 283)1 289)2 295)2 301)1 307)2 313)3 319)1 236)2 242)2 248)1 254)1 260)2 266)2 272)4 278)4 284)3 290)3 296)4 302)1 308)2 314)3 320)4 SHARPEN YOUR REFLEXES(E-II) 321)1 322)2 323)3 324)3 325)3 326)3 327)3 328)1 329)3 330)2 331)2 332)4 THINK TWICE BEFORE YOU CHOOSE (E-III) 333)3 339)2 345)3 351)1 357)1 334)2 340)2 346)3 352)1 335)1 341)1 347)1 353)1 336)3 342)1 348)1 354)3 337)2 343)3 349)3 355)3 338)2 344)4 350)1 356)1 SIMPLE MATCHING QUESTIONS (E– IV) 358)3 364)1 359)3 365)1 360)2 361)2 362)1 363)3 366)1 367)1 MULTIPLE MATCHING QS (E– V) 368)1 373)2 378)1 369)3 374)1 370)3 371)2 372)3 375)2 376)3 377)1 QUESTIONS FROM PREVIOUS MEDICAL EXAMINATIONS (E-VI) 379)2 385)1 391)3 397)1 403)4 409)3 415)1 421)3 427)4 433)3 380)2 386)2 392)3 398)4 404)4 410)1 416)1 422)2 428)4 434)1 381)2 387)3 393)1 399)2 405)1 411)4 417)3 423)2 429)1 435) 3 382)1 388)4 394)2 400)3 406)3 412)2 418)2 424)2 430)2 436)1 383)3 389)4 395)3 401)2 407)1 413)1 419)2 425)1 431)1 437)2 384)2 390)2 396)2 402)4 408)4 414)2 420)2 426)1 432)2 135 UNIT - III :GENETICS Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION TRUE OR FALSE STATEMENT (E-VII) 438) F 443) F 448) T 453) T 458) F 463) T 468) T 473) F 478) F 483) T 488) T 439) F 444) T 449) T 454) T 459) T 464) F 469) T 474) T 479) T 484) T 489) T 440) T 445) F 450) F 455) F 460) F 465) T 470) T 475) F 480) T 485) T 490) T 441) F 446) F 451) T 456) T 461) T 466) F 471) F 476) T 481) T 486) T 491) T 442) F 447) T 452) T 457) F 462) T 467) T 472) T 477) T 482) T 487) F 492) T HINTS FOR EXCERSISE - III 333. In a test cross F1 organism is crossed with recessive parent hence R is false. 334.both are true but not explains. 335.In Lentil plant the heterozygous F1 individual show the phenotypic features of both the parents which means that neither “spotted” nor “dotted” allele is dominant or recessive to other and the alleles are co-dominant, hence R explains A. 336.Production of more than one character by one single gene is called pleiotrophism. 337.Both are true but are not related. 338.Both linkage and recombination are individual definitions but are not related. 339.Both are true but are not related 340.Assertion explains what are chromosomal aberrations and the reason explains where they commonly occurred so they are not related. 341.Sickle cell anemia is because of change occurs in a single base pair of DNA hence it is point mutation. 342.U.V radiation can cause mutations in organisms hence U.V radiation is a mutagen. 343.In a dihybrid cross conducted by Mendel, fortunately the pairs of factors are located in two pairs of homologous chromosomes and generally each homologous pair of chromosome bears only one pair of factors or alleles for one gene hence R is false. 344.Hybrids produced by hybridization process may have undesirable genes along with the desired genes, hence A is false. 345.Crossing can occur in between two weakly linked genes so R is false. 346.Pea plant is self pollinated member of Fabaceae but not Solanaceae hence R is false. 347.In Mendel monohybrid cross F1 individual are in heterozygous condition (Tt). They produce gametes like female T, female t & male T, male t. Hence R explains A. 348.If distance between genes on a chromosome is less then linkage is more, if distance is more then linkage 136 SR.BOTANY EAMCET - VOL - I is weak so Linkage is inversely proportional to distance between genes. 349.F1 individuals of monohybrid cross show alleles for tallness (T) and for dwarfness (t), but because complete dominance only tall phenotype is expressed. So the probability of obtaining dwarf plants in F1 is zero. Hence R is false. 350.As the heterozygotes show the phenotype that is inbetween the two parents , so the phenotypic and genotypic ratios are same. Hence R explains A. 351.Usually chromosomes are made up of DNA and histone proteins. One chromatid (anaphase chromosome) is made upof only one DNA. if loss or gain in that segment causes alternation of chromosomes, so R explains A. 352.Fortunately characters selected by Mendel for his hybridization experiments in pea were on different chromosomes, but not two characters selected by Mendel for a dihybrid cross on a same chromosome. So the characters are independently assorted and results in the formation of recombinants, So R explains A. 353.Back cross involves the cross between F1 individual with either dominant or recessive parent, where as test cross is a type of back cross in which only recessive parent is involved.hence test cross is also a type of back cross. 354.Mendel conducted hybridization experiments in garden plant ( Pisum sativum) but not in Wild pea ( Lathyrus sativus), hence R is false. 355.A breeder can select only desirable mutations, but not undesirable mutations. 356.Usually The linked genes tend to get inherited together so they reduces the possibility of gametes production, so they produce more number of parental combinations. 357.As the factors selected by Mendel present on different chromosomes so they are independently assorted, so Mendel didn’t find any linkage in pea plant. Hence R explains A. HINTS FOR TRUE OR FALSE STATEMENTS (E-VII) 379.Mendel’s factors were today’s genes hence the statement is false. 380.Krebs and Calvin are related to physiology but not molecular biology hence it is false statement 381.One of the causes of variation was hidden in sexual reproduction hence it is true statement. 382.Artificial selection (but not natural selection) and breeding are the key process in the development of Sahiwal Cows in Punjab and Ongole bulls in A.P , hence it is a false statement 383.Mendelian general rules of inheritance were substantiated ideas, hence it is a false statement 384.Pea plants are self fertilized conveniently hence it is false statement. NARAYANAGROUP UNIT - III :GENETICS SR.BOTANY EAMCET - VOL - I Chapter-9 : PRINCIPLES OF INHERITANCE AND VARIATION 385.According to Mendelian rules, F1 is always similar to one of the parents, hence it is true statement 386.Emasculation is not required for obtaining F2 generation in Mendelian monohybrid cross because they are produced by self pollination 387.Mendel was an Austrian but not Australian monk hence it is a false statement. 388.The phenotype height is represented with the genotypes TT or Tt or tt hence it is true statement. 389.In order to express recessive character, both alleles must be recessive. Hence the statement is true. 390.If dwarf plants with ‘tt’ genotype are self crossed they are going to produce only dwarf plants hence the statement is true. 391.Checker Board developed by British geneticist but not chemist, hence it is false statement. 392.Recessive trait may not be in heterozygous because it requires two recessive alleles, hence it is a true statement. 393.During formation of gametes, the paired unit factors separate randomly with equal probability due to meiosis hence it is true statement. 394.Generally gametes are pure for their factor they posses hence it is true statement. 395.F1 hybrid is crossed with parental type having dominant trait in homozygous condition, the number of recombinant individuals is 0% hence it is true statement. 396.Pleiotropy means a single gene is responsible for many characters,hence it is false statement. 397.Mutations can generate large number of variability with in the population. Hence a breeder can use desirable mutations, hence it is true statement. 398.Alternative form a character is called contrasting traits but not alleles, hence it is a false statement. 399.In co-dominance the phenotypic ratio of F2 progeny is 1 : 2 : 1 but not 3 : 1, hence it is a false statement. 400.Drosophila is morphologically easily distinguishable based on sex, because females are larger than males. Hence it is a true statement. 401.According to concept of linkage, two or more genes of a chromosome are linked but not two alleles of same gene. Hence it is a false statement. 402.Mendel proposed his law of independent assortment based on results on dihybrid cross, hence it is a true statement. 403.Alleles of same gene are present on similar locations of homologous chromosomes. Hence it is true statement. 404.The probability of double homozygous individuals in F2 generation Mendel dihybrid cross is 1/4. Hence it is a true statement. 405.Externally it is not possible to distinguish between the plants with the genotypes TT and Tt because the genotype, an organism can not be predicted by physical appearance. Hence it is false statement . 406.In a test cross, dominant phenotype is crossed NARAYANAGROUP with recessive parent instead of self fertilization hence it is true statement. 407.Genes can be mutated hence it is false statement. 408.Dominance is not an autonomous feature of a gene, because it depends upon the phenotype produced by the product. Hence it is a false statement. 409.Linkage is inversely proportional to distance between the genes of the same chromosome. Hence it is true statement. 410.Mutations first discovered by Hugo de Vries. Hence it is a true statement. 411.The term linkage coined by T.H. Morgan. hence it is true statement. 412.RBC that determining ABO blood group and seed coat pattern example for co - dominance. Hence it is a false statement. 413.In dihybrid cross of Morgan, the proportion of parental gene combination was much higher than the non parental type because he found linkage in Drosophila, hence it is true statement. 414.Chromosomal theory of inheritance proposed by Sutton and Boveri but not Watson and Crick. Hence it is a false statement. 415.Mendel dihybrid test cross ratio is 1 : 1 : 1 : 1. Hence it is true statement. 416.Co - dominance is not seen in Snapdragon. Hence it is a false statement. 417.Generally gametes are pure for the factors they possess. Hence it is true statement. 418.Number of monohybrids in typical dihybrid is 8. Hence it is a true statement. 419.Several dihybrid crosses in Drosophila were carried out by T.H.Morgan. Hence it is a false statement. 420.Number of phenotypes in monohybrid test cross is 2 and genotypes also is 2. hence it is true a statement. 421.Number of double dominant individuals(RRYY) in Mendel dihybrid F2 progeny is 1. Hence it is true statement. 422.Chromosomal aberrations are commonly observed in cancer cells. Hence it is true statement. 423.Factors are discrete units which controls characters. Hence it is true statement. 424.Unit factors occurs in paired condition. Hence it is true statement. 425.Sickle cell anemia is a classical example for point mutation. Hence it is true statement. 426.The change in a single base pair of DNA is called point mutation. Hence it is a true statement. 427.Deletions and insertions of base pairs of DNA cause frame shift mutations. Hence it is true statement. 428.UV radiations is an example of physical mutagen but not chemical mutagen, Hence it is a false statement. 429.Desirable mutations helps in crop improvement. Hence it is true statement. 137