Immune System The Body’s Defenses How Does The Body Protect Against Infection? 1st Line of Defense (1) (2) 2nd Line of Defense 3 important defenses 1) __________________________________: series of events that suppress infection and speed recovery Cells release histamine- _____________________________________________ ___________________________________________________________________ Causes swelling and redness 1 ________________ (white blood cells, dead cells, and dead pathogens) 2) __________________________________________: body temperature _____________________ several degrees above normal when body begins to fight against pathogen 3) _________________________________: _____________________________: engulf and destroy pathogens (most abundant) release chemical that kills bacteria and themselves. ______________________________: ingest and kill pathogen - travel through body in blood and fluid between cells. _______________________________:- attack cells infected with pathogens punctures cell membrane letting water in 2 (cytolysis) 3rd Line of Defense (IMMUNITY) Organs of immune system include bone marrow (makes WBC’s), thymus, lymph nodes (filters), tonsils, and spleen (filters) These WBC’s are called ___________________________________ Active Immune System There are two main types of lymphocytes: __________________________ _______________________– produced in bone marrow, and responsible for producing ___________________________ 3 ___________________: attack and kill infected cells ____________________________ are regulated by ______________________ 4 Transmission Protection Autoimmune Diseases How are Diseases Transmitted? How Does One Become Resistant to Disease? Immunity: There are two types of immunity 1) _____________________________________ 2) _____________________________________ Active Immunity 5 long lasting Passive Immunity - Naturally: through the placenta. - Artificially: as by injection of antiserum What Happens When the Immune System attacks Body Tissues? Autoimmune Disease Affects organs and tissues throughout the body Example: Multiple Sclerosis Destroys insulating material surrounding nerve cells in the brain and spinal cord 6 Type 1 Diabetes Affected area: Symptoms – Increased blood glucose level, excessive urine production, problems with vision, weight loss, fatigue irritability How does HIV Infection lead to Immune System Collapse? How does one test for HIV? 7