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Barron's AP Biology Review
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Terms in this set (1125)
matter
anything that has mass and takes up
space
proton
A subatomic particle that has a positive
charge and that is found in the nucleus
of an atom
neutron
A subatomic particle that has no charge
and that is found in the nucleus of an
atom
electron
A subatomic particle that has a negative
charge
ground state
state of atom in which all the electrons
are in the lowest available energy levels
excited state
state of atom in which one or more
electrons moves to a higher energy level
when atom absorbs energy
isotope
atoms of one element that vary only in
the number of neutrons in the nucleus
(but are still chemically identical
because same number of electrons in
same configuration)
half-life
known rate of radioactive decay of some
radioisotopes
radioisotopes
radioactive isotopes
radioactive iodine
radioisotope used to diagnose and treat
(iodine-131)
thyroid gland diseases
tracer
radioisotopes incorporated into a
molecule and used to trace its path in a
metabolic pathway
ionic bond
bond resulting from transfer of electrons
covalent bond
bond result from sharing of electrons
anion
negative ion (e.g. Cl-)
cation
positive ion (e.g. Na+, K+, Ca++)
molecule
structure of atoms formed by covalent
bonds
nonpolar bond
covalent bond when electrons shared
equally between two identical atoms
(e.g. H-H)
diatomic molecule
molecule formed by two atoms of the
same element with a non-polar bond
(e.g. O-O)
polar bond
covalent bond when electrons shared
unequally between two different atoms
(e.g. C-H)
nonpolar molecule
electrons balanced and symmetrical in a
molecule (e.g. carbon dioxide)
polar molecule
electrons unbalanced in a molecule (e.g.
water)
hydrophilic
"water-loving", soluble in water (e.g.
polar molecules, ions, charged
substances)
hydrophobic
"water-hating", insoluble in water instead
lipids (e.g. nonpolar molecules)
universal solvent
water dissolves so many substances
hydrogen bond
bond formed by weak attraction
between a hydrogen atom and another
atom resulting from ionic or polar
charges
specific heat
the amount of heat a substance must
absorb to increase the temperature of 1
gram of a substance by 1 degree C; high
for water
heat of vaporization
the energy a substance must absorb in
order to change from a liquid to a gas;
high for water
cohesion tension
molecules of a substance attract one
another; strong for water
transpirational-pull
water moves up from roots to leaves
cohesion tension
without expenditure of energy using
transpiration
capillary action
force resulting from cohesion and
adhesion
surface tension
type of cohesion enabling water to not
break when touch surface lightly
spring overturn
cycling of nutrients in the lake when ice
melts, becoming denser and sinking to
circulate water and nutrients around the
lake
pH
negative log of the hydrogen ion
concentration; measure of acidity and
alkalinity of a solution
buffer
substance that resists change in pH
bicarbonate ion
most important buffer in human blood
isomer
organic compounds that have same
molecular formula but different
structures
structural isomer
isomer that differs in arrangement of
atoms
cis-trans isomer
isomer that differs only in spatial
arrangement around flexible double
bonds
enantiomer
isomer that is a mirror image (L for lefthanded and D for right-handed)
carbohydrate
organic compound formed by carbon,
hydrogen, and oxygen where hydrogen
is always twice the oxygen; used for fuel
and building materials
monosaccharide
monomer of carbohydrates; C6H12O6
glucose
monosaccharide that is the main sugar
source
fructose
monosaccharide found in honey and
fruits
galactose
monosaccharide found in milk
disaccharide
carbohydrate formed by joining two
monosaccharides; C12H22O11
dehydration synthesis
two monomers joined together with the
release of one molecule of water
condensation
another name for dehydration synthesis
maltose
disaccharide formed by two glucose
lactose
disaccharide formed by one glucose
and one galactose
sucrose
disaccharide formed by one glucose
and one fructose
hydrolysis
breakdown of organic compound by
adding water
polysaccharide
polymers of carbohydrates formed by
many monosaccharides joined together
by condensation reactions
cellulose
structural polysaccharide that makes up
plant cell walls
chitin
structural polysaccharide that makes up
fungal cell walls and the exoskeleton of
arthropods
starch
storage polysaccharide for plants; two
forms are amylose and amylopectin
glycogen
storage polysaccharide for animals;
found in liver and skeletal muscle
lipid
hydrophobic organic compound
fat
lipid for energy storage formed by
glycerol and three fatty acids that is
solid at room temperature
oil
lipid for energy storage formed by
glycerol and three fatty acids that is
liquid at room temperature
wax
lipid that is an ester of a fatty acid and
alcohol
steroid
lipid consisting of four fused rings
glycerol
three-carbon alcohol with each carbon
containing a hydroxyl group
fatty acid
hydrocarbon chain with a carboxyl
group at one end
saturated fatty acid
fatty acid with only single bonds; solid at
room temperature, come from animals,
unhealthier
unsaturated fatty acid
fatty acid with at least one double bond;
liquid at room temperature, come from
plants, healthier
phospholipid
modified lipids consisting of only two
fatty acids and one phosphate group
attached to glycerol backbone; make up
cell membrane
protein
complex, unbranched macromolecules
that carry out many functions made of
amino acids of sulfur, phosphorus,
carbon, oxygen, hydrogen, and nitrogen
polymer
molecule consisting of many units called
monomers
polypeptide
polymer of amino acids; not same as
protein
amino acid
monomer of proteins
peptide bond
bond that joins amino acids in
polypeptides
carboxyl group
carbon double-bonded to oxygen and
bonded to hydroxyl
amine group
nitrogen bonded to two hydrogens
variable (R) group
attached to carbon backbone that is
variable for amino acids
dipeptide
molecule consisting of two amino acids
connected by one peptide bond formed
by dehydration synthesis
conformation
unique shape of a protein that
determines its function
primary structure
unique linear sequence of amino acids
secondary structure
hydrogen bonding within polypeptide
molecule
tertiary structure
intricate three-dimensional shape or
conformation of protein that is
superimposed on its secondary
structure
quaternary structure
proteins that consist of multiple
polypeptide chains
alpha helix
the spiral shape of a protein's secondary
structure (e.g. keratin)
beta-pleated sheet
the bended or folded form of a
secondary structure (e.g. silk and spider
webs)
fibrous protein
proteins that exhibit either alpha helix or
beta-pleated sheet
keratin
fibrous protein of mainly alpha helix that
makes up human hair
specificity
precise form of tertiary structure that
determines function
denaturation
adverse conditions that alter the weak
intermolecular forces that causes the
protein to lose its characteristic shape
and function
chaperonin
protein that assists in folding other
proteins
prion
misfolded protein that when
accumulated in brain, cause disease
X-ray crystallography
used to determine the 3D structure of
many other proteins
bioinformatics
uses computation and math modeling to
predict three-dimensional structure of
resulting protein molecule
nucleic acid
polymer of nucleotides that encodes
hereditary information
ribonucleic acid
single-stranded nucleic acid containing
ribose and uracil
deoxyribonucleic acid
double-stranded nucleic acid containing
deoxyribose and thymine
nucleotide
monomer consisting of phosphate, fivecarbon sugar, and nitrogenous bases
nitrogenous base
identifies a nucleotide; e.g. adenine,
cytosine, guanine, thymine, uracil
functional group
components of organic molecule
involved in chemical reaction
theory of
theory that mitochondria and
endosymbiosis
chloroplasts were once free-living
prokaryotes that merged with larger
prokaryotes to form eukaryotes
eukaryotic cell
cell with nucleus and membrane-bound
organelles
prokaryotic cell
cell without nucleus or membranebound organelles
cytosol
semifluid substance in which subcellular
components are suspended
nucleoid region
non-membrane-bound region where
chromosome is located in prokaryotes
nucleolus
tangle of chromatin and unfinished
ribosomal precursors inside nucleus that
produces ribosomal RNA and the large
and small subunits of ribosomes
ribosome
non-membrane-bound structures that
produce protein; free (intracellular
proteins) or attached (exported proteins)
peroxisome
perform specialized function that
converts hydrogen peroxide into water
and detoxifies alcohol in liver cells
catalase
enzyme that converts hydrogen
peroxide (waste product of respiration)
to water with the release of oxygen
atoms
endomembrane system
intracellular system that regulates
protein traffic and performs metabolic
functions in cells
nucleus
double-membrane-bound control
center of cell; contains chromosomes
wrapped with special proteins
chromatin network
chromosomes wrapped with special
proteins
nuclear envelope
selectively permeable membrane that
separates the contents of the nucleus
from the cytoplasm
pore
hole in nuclear envelope that allows
transport of large molecules e.g. mRNA
rough endoplasmic
endoplasmic reticulum studded with
reticulum
ribosomes and produces proteins
smooth endoplasmic
endoplasmic reticulum that assists in the
reticulum
synthesis of steroid hormones, stores
calcium ions for muscle cells, and
detoxifies drugs and poisons from the
body
endoplasmic reticulum
membranous system of channels and
flattened sacs that traverse the
cytoplasm
Golgi apparatus
organelle of flattened stacked
membranous sacs that process and
packaged substances from the rough
endoplasmic reticulum and secretes the
substances to other parts of the cell
lysosome
sac of hydrolytic enzymes that performs
intracellular digestion
hydrolytic enzyme
enzyme that digests
intracellular digestion
breaks down molecule inside the celel
autophagy
continuous renewal by breaking down
and recycling cell parts
apoptosis
programmed destruction of cells by
own hydrolytic enzymes
cristae
inner series of membranes inside a
mitochondria
mitochondrion
double-membrane-bound site of cellular
respiration with its own DNA
contractile vacuole
structure in freshwater protists to pump
out excess water
food vacuole
vacuole formed when solid material
enters cell
thylakoid
inner membrane system of chloroplasts
cytoplasmic streaming
flow of the cytoplasm directed by
cytoskeleton
cytoskeleton
complex mesh of protein filaments that
extends throughout the cytoplasm
microtubules
hollow tubes made of the protein tubulin
(mainly for movement)
cilium
shorter movement structure consisting
of 9 pairs of microtubules organized
around 2 singlet microtubules
flagellum
longer movement structure consisting of
9 pairs of microtubules organized
around 2 singlet microtubules
spindle fiber
help separate chromosomes during cell
division that consists of microtubules
organized into 9 triplets
microfilament
filaments assembled from actin filament
to help support shape of cell
actin filament
actin proteins that make up
microfilaments
psuedopod
microfilament-directed movement for
amoebas
centriole
organize spindle fibers and give rise to
spindle apparatus
centrosome
two centrioles oriented at right angles at
each other
microtubule organizing
plant cell synonym of centrosome
center
cell wall
cell structure not found in animal cells
that functions for structural purposes
primary cell wall
cell wall immediately outside the plasma
membrane
secondary cell wall
cell wall underneath the primary cell
wall
middle lamella
thin gluey layer formed between cell
walls of two new plant cells after
division
cell membrane
border of the cell between cytoplasm
and environment
selectively permeable
applies to how membranes regulate the
steady traffic that enters and leaves the
cell
fluid mosaic model
coined by SJ Singer in 1972 that
describes how lipids and proteins in
membrane keep moving
phospholipid bilayer
phospholipids have heads out and tails
in to form the cell membrane
amphipathic
has both a hydrophobic and hydrophilic
region
integral protein
proteins that completely span the
membrane and have nonpolar regions
peripheral protein
proteins loosely bound to the surface of
the membrane
cholesterol
steroid embedded in the interior of the
bilayer to stabilize the membrane
glycolipid
carbohydrate covalently bonded to
lipid, serve as signaling molecules
glycoprotein
carbohydrate covalently bonded to
carbohydrate, serve as signaling
molecules
desmosome
a structure by which two adjacent cells
are attached, formed from protein
plaques in the cell membranes linked by
filaments
adenylate cyclase
enzyme that converts ATP to cyclic AMP
tight junction
a firm seal between two adjacent animal
cells created by protein adherence
transport
movement of substances into and out of
a cell
passive transport
transport that does not require energy
diffusion
random movement of molecules of
other particles from a higher
concentration to a lower concentration
osmosis
diffusion of water across a membrane
simple diffusion
diffusion that does not involve protein
channels but rather directly across the
membrane - hydrophobic, small
facilitated diffusion
diffusion that involves protein channels hydrophilic, large, charged
hydrophilic protein
protein channel that passively transports
channel
specific substances across the
membrane
countercurrent
flow of adjacent fluids in opposite
exchange
directions that maximizes the rate of
simple diffusion (esp. fish gills)
solvent
substance that does the dissolving
solute
substance that dissolves
hypertonic
having greater concentration of solute
than another solution
hypotonic
having lesser concentration of solute
than another solution
isotonic
two solutions containing equal
concentration of solutes
osmotic potential
tendency of water to move across a
permeable membrane into a solution
water potential
results from two factors - solute
concentration and solute pressure
turgid
swollen plant cell in hypotonic solution
turgor pressure
water flows into a cell and exerts
pressure onto cell wall
plasmolysis
plant cell cytoplasm shrinks in
hypertonic solution
aquaporin
special water channel protein found in
certain cells that facilitate the diffusion
of massive amounts of water across a
cell membrane
gated channel
protein channels that open and close in
response to variables of a cell
active transport
movement of molecules against a
gradient that requires energy, usually in
the form of ATP
pump
active transport protein that pumps
particles across membrane
carrier (protein)
active transport protein that carries
particles across membrane
sodium-potassium
pumps sodium and potassium ions
pump
across a nerve cell membrane to return
the nerve to its resting state (3 Na+ out
cells and 2 K+ into cells)
exocytosis
active transport that releases vesicle
contents (e.g. neurotransmitters into
synapse)
pinocytosis
"cell drinking", uptake of large, dissolved
particles
phagocytosis
engulfing of large particles or small cells
by pseudopods
receptor-mediated
endocytosis that enables a cell to
endocytosis
endocytose very specific substances
ligand
any molecule that binds specifically to a
receptor site of another molecule
coated vesicle
vesicle formed when receptors with
ligand turn inward to membrane
bulk flow
overall movement of fluid in one
direction in a norganism
source
where something originates
sink
where something is used
quorum sensing
form of bacterial communication that
allows bacteria to monitor population
density and use that information to
control gene expression
bioluminescence
conversion of energy stored in certain
organic molecules to light
luciferase
enzyme that triggers the expression of
luciferin to produce light for
bioluminescence
luciferin
protein that produces light for
bioluminescence
gap junction
direct contact communication that
permits the passage of materials directly
from the cytoplasm of one cell to the
cytoplasm of an adjacent cell; often with
neurons and cardiac cells
plasmodesma
analog of gap junction in plant cells; an
open channel in the cell walls of plant
cells allowing for connections between
the cytoplasm of adjacent cells
growth factor
local signal from nearby cells that give
instructions to grow and divide
synaptic signaling
signaling when a neuron releases
neurotransmitters into a synapse to
stimulate an adjacent neuron to fire or a
muscle to contract
reception
ligand from outside target cell binds
with a receptor either on the surface of
or inside the target cell
transduction (signal)
the signal is converted to a form that can
bring about a specific cellular response
response
a specific cellular reaction occurs, either
by regulation of transcription or by
cytoplasmic action
cell membrane
receptors that span the entire thickness
receptors
of the membrane and are therefore in
contact with both the extracellular
environment and the cytoplasm
hydrophilic signaling
ligand that binds to extracellular part of
molecule
cell membrane receptor to change the
shape on the cytoplasmic side
second messenger
a molecule that carries a signal from the
cell membrane receptor throughout the
cytoplasm
cyclic AMP
a common intracellular signaling
molecule made from ATP
ion-channel receptor
allosteric cell membrane receptor that
opens and shuts a gate in a membrane
to allow an influx of ions (e.g. Na+)
G-protein coupled
cell membrane receptor that binds on a
receptor
ligand on the extracellular and activates
G protein which activates adenylyl
cyclase to produce cAMP
first messenger
ligand as opposed to second
messenger
G protein
signaling protein that when activated,
bonds to GTP to activate adenylyl
cyclase
adenylyl cyclase
enzyme that converts ATP into cAMP
receptor tyrosine
cell membrane receptor with enzymatic
kinase
activity that aggregates with each other
to activate specific relay proteins by
phosphorylation to tyrosines
intracellular receptor
receptor that is located inside of the cell
and binds to small, nonpolar ligands that
passed through the cell membrane
nitric oxide
gas with chemical formula NO that is like
hormones; can be used with
acetylcholine to stimulate more cells
bisphenol A
chemical present in many plastics that
mimics estrogen and causes fetal
developmental problems
signal transduction
multistep process in which a small
pathway
number of extracellular signal molecules
is amplified to and produces a major
cellular response
cascade effect
a small number of extracellular signal
molecules produce a major cellular
response
caspase
class of enzymes that carry out
apoptosis
mitosis
dividing of the nucleus process that
produces two genetically identical
daughter cells and preserves the diploid
chromosome number
meiosis
dividing of the nucleus process in
sexually reproducing organisms that
results in haploid cells
clone
geneticaly identical daughter cell
sister chromatid
one of two exact copies in a replicated
chromosome
centromere
specialized region that holds the two
chromatids together
kinetochore
disc-shaped protein on the centromere
that attaches the chromatid to the
mitotic spindle during cell division
cell cycle
complex sequence of growth and
division in cells
G0 phase
phase during which cells arrested and
not proceeding to divide until stimulus
interphase
period of cell cycle between cell
divisions
G1 phase
period of intense growth and
biochemical activity
S phase
synthesis or replication of DNA
G2
phase when cell continues to grow and
make preparations for cell division
prophase
mitotic phase during which
chromosomes condense, nuclear
membrane breaks, and spindle begins to
form
metaphase
mitotic phase during which
chromosomes line up in a single line
metaphase plate
single line located on the equator where
chromosomes are positioned during
metaphase
anaphase
mitotic phase during which spindle pulls
sister chromatids apart
telophase
mitotic spindle during which nucleus
begins to reform condensed
chromosome
cytokinesis
dividing of the cytoplasm
cleavage furrow
microfilament structure that helps to
separate cells during cytokinesis
contact (or density-
normal cells grow and divide until
dependent) inhibition
overcrowded
anchorage
cell must divide while attached to
dependence
surfaces or extracellular membrane
gamete
sex cell
haploid
half the genetic material as normal
diploid
two sets of chromosome for each gene
meiosis I
meiotic section during which
homologous chromosomes separate
reduction division
term applied to meiosis I because
daughter cells haploid
synaptonemal complex
complex between each chromosome
and its homologue
synapsis
each chromosome lines up with its
homologue
tetrad
two pairs of homologous chromosomes
that participate in prophase I
bivalent
alternative name for tetrad
crossing-over
process by which nonsister chromatids
exchange genetic material, resulting in
recombination
chiasma
regions on chromosome where
homologous bits of DNA are switching
place; physical bridge built around the
point of crossing-over
meiosis II
meiotic section similar to mitosis
prophase I
pairing of homologues to form tetrads,
nucleus breaks, etc.
metaphase I
tetrads line up at metaphase plate
double file
how the tetrads line up during
metaphase I
anaphase I
spindle fibers separate homologous
chromosomes
telophase I
homologous pairs of chromosomes form
new nuclei with haploid number
independent
each homologous chromosome chooses
assortment of
which gamete
chromosomes
recombinant
chromosome that contains genes
chromosome
inherited from both parents due to
crossing-over
random fertilization
one sperm and one ovum are randomly
chosen
cell cycle control
control system that regulates the rate at
system
which cells divide
checkpoint
built-in stop signals that halt the cell
unless they are overridden by go-ahead
signals
restriction point
checkpoint during G1 that determines
whether cell will complete cell division
or exit the cycle to become a
nondividing cell arrested in G0
cyclin
protein whose levels cyclically rise and
fall in dividing cells, synthesized during S
and G2 but broken down after M
kinase
protein that activates other proteins by
phosphorylation
cyclin-dependent
kinase critical to the cell cycle that is
kinase
activated only when bound to a cyclin
cyclin-Cdk complex
cyclin-dependent kinase (use abbrev
Cdk) binds to a cyclin
MPF
maturation promoting factor, cyclin-Cdk
complex that triggers cell's passage
from G2 to metaphase that helps
chromosome condensation and spindle
formation during prophase
energy
the ability to do work or cause change
enzyme
biological catalyst
first law of
energy cannot be created or destroyed,
thermodynamics
only transformed from one form to
another (thermo)
law of conservation of
energy cannot be created or destroyed,
energy
only transformed from one form to
another (energy)
second law of
during energy conversions, entropy
thermodynamics
increases (i.e. the Universe becomes
more disordered)
Gibbs free energy
how much free energy available to do
work
exergonic
energy released during reaction; power
endergonic
endergonic
energy absorbed during reaction;
supported by exergonic
metabolism
sum total of all the chemical reactions
that take place in cells
catabolism
reactions that break down molecules
anabolism
reactions that build up molecules
pathway
series of metabolic reactions that serves
a specific cellular function
energy of activation
the amount of energy needed to begin a
reaction
transition state
reactive condition of the substrate after
sufficient energy has been absorbed to
initiate the reaction
globular protein
protein that isi spherical
induced-fit model
as the substrate enters the active site, it
induces the enzyme to alter its shape
slightly so the substrate fits better
enzyme-substrate
complex
substrate bound to enzyme
cofactor
inorganic (e.g. mineral) that helps
enzymes
coenzyme
organic (e.g. vitamin) that helps enzyme
competitive inhibition
compounds resembling the substrate
molecules compete for the same active
site on the enzyme
competitive inhibitor
compounds that mimic substrate
molecules and reduce the amount of
product by preventing or limiting the
substrate from binding to the enzyme
allosteric
change in enzyme shape alters its
efficiency
noncompetitive
molecules that bind to a site distinct
inhibitor
from the active site of the enzyme to
cause the enzyme to change shape that
inhibits the enzyme from catalyzing the
substrate to product reaction (n)
allosteric regulator
molecules that bind to a site distinct
from the active site of the enzyme to
cause the enzyme to change shape that
inhibits the enzyme from catalyzing the
substrate to product reaction (a)
feedback inhibition
end product of lengthy metabolic
pathway is the allosteric inhibitor for an
enzyme that catalyzes an early step in
the pathway
cooperativity
binding of one substrate molecule
causes a change in the entire molecule
to lock all subunits in an active position
and amplifies the response
adenosine triphosphate
molecule that stores energy instantly
available for every cellular activity
glycolysis
ten-step process that breaks down one
molecule of glucose into two molecules
of pyruvate to release 2 ATP
reduction
gain of electrons or hydrogen
oxidation
loss of electrons or hydrogen
redox reaction
reaction in which one substance
reduced and the other is oxidized
adenosine
adenine plus ribose
pyruvate
three-carbon molecule formed by
glycolysis
phosphofructokinase
enzyme that catalyzes the third step of
glycolysis; high ATP levels alters
conformation of enzyme
outer compartment
intermembrane space of the
mitochondria
matrix
innermost region of the mitochondria
Krebs cycle
cyclical series of enzyme-catalyzed
reactions that oxidizes pyruvate to
carbon dioxide
substrate level
direct enzymatic transfer of a phosphate
phosphorylation
to e.g. ADP
NAD+ (nicotinamide
coenzyme carrying protons or electrons
adenine dinucleotide)
from glycolysis and Krebs cycle to the
electron transport chain
acetyl-CoA
first reactant of the Krebs cycle formed
by combining coenzyme A with
pyruvate
FAD (flavin adenine
coenzyme carrying protons or electrons
dinucleotide)
from and Krebs cycle to the electron
transport chain
NAD dehydrogenase
enzyme that catalyzes the transfer of
hydrogen atoms from substrate e.g.
glucose to NAD+
FAD dehydrogenase
enzyme that catalyzes the transfer of
hydrogen atoms from substrate e.g.
glucose to FAD+
citric acid cycle
common name for Kreb's cycle
electron transport
proton pump in the mitochondria that
chain
couples the endergonic pumping of
protons with the exergonic
chemiosmosis
proton pump
protein pump that pumps protons across
the membrane
proton gradient
concentration gradient of proteins
final electron acceptor
oxygen is at the end of the ETC
oxygen
highly electronegative element, that is
the final electron acceptor
cytochrome
protein on the ETC structurally similar to
hemoglobin, present in all organisms so
can trace back evolutionary relationships
oxidative
phosphorylation of ADP into ATP by the
phosphorylation
oxidation of the carrier molecules
NADH and FADH2
energy-coupling
mechanism that couples endergonic
mechanism
with exergonic reactions
ATP synthase channels
protein channels that allow protons to
diffuse across membrane and
phosphorylate ADP to ATP
chemiosmosis
harnessing concentration gradient to
produce ATP
anaerobic respiration
anaerobic, catabolic process including
glycolysis and alcohol/lactic acid
fermentation
botulinum
bacterium that causes food poisoning
facultative anaerobe
tolerate the presence of oxygen but
cannot use
obligate aerobe
require oxygen to survive
obligate anaerobe
die in oxygen-rich environmnent
alcoholic fermentation
certain cells convert pyruvate into ethyl
alcohol and carbon dioxide and oxidize
NADH back to NAD+ (e.g. yeast)
lactic acid fermentation
certain cells (e.g. liver) convert pyruvate
into lactate and oxidize NADH back to
NAD+
photosynthesis
process by which light energy is
converted to chemical bond energy and
carbon is fixed into organic compounds
photosynthetic pigment
pigment that absorbs light energy and
uses it to provide energy to carry out
photosynthesis
chlorophyll a
pigment that participates directly in the
light reactions of photosynthesis;
absorbs red, blue, and violet ranges
chlorophyll b
antenna pigment for photosynthesis;
absorbs red, blue, and violet ranges
carotenoid
antenna pigment for photosynthesis;
absorbs green, blue, and violet ranges
xantophyll
antenna pigment for photosynthesis that
has a slight chemical variation from
carotenoids
phycobilin
antenna pigment for photosynthesis;
absorbs blue, green ranges
action spectrum
graph showing how independent
variable is plotted against rate of
photosynthesis
magnesium
single atom in middle of chlorophyll
head
granum
stack of thylakoids, site of lightdependent reactions
light-dependent
first part of photosynthesis that uses
reactions
energy to produce ATP to power the
light-independent reactions
light-independent
second part of photosynthesis that uses
reactions
ATP from the light-dependent reactions
to produce sugar
stroma
chloroplast fluid outside grana where
light-independent reactions occur
photosystem
light-harvesting complex in the thylakoid
membranes of chloroplasts
reaction center
part of photosystem consisting of
chlorophyll a and several hundreds
antenna pigments
photosystem I
P700, excites electrons to replace those
from the ETC
photosystem II
P680, source of electrons for the ETC
noncyclic
electrons enter two electron transport
photophosphorylation
chain and produces ATP and NADPH
primary electron
first molecule in PSII to capture
acceptor
electrons from photons
photolysis
splitting of water to provide electrons to
replace those lost from chlorophyll a in
P680
photophosphorylation
ATP synthesis powered by light
lumen
space inside thylakoid membranes
cyclic phosphorylation
light-dependent reactions pathway to
replenish the ATP levels by using only
PSI
Calvin cycle
main component of light-independent
reactions
PGAL
3-carbon sugar that is the end product
(phosphoglyceraldehyd
of the Calvin cycle
e)
carbon fixation
the incorporation of carbon from
carbon dioxide into an organic
compound by an autotrophic organism
RuBP (ribulose
starting molecule for the Calvin cycle
biphosphate)
RuBisCo (ribulose
enzyme that catalyzes first step of
biphosphate
Calvin cycle when carbon fixed onto
carboxylase)
RuBP
3-PGA (3-
3-carbon molecule formed right after
phosphoglycerate)
RuBisCo fixes a carbon because 6carbon is unstable
C3 plants
plants whose first step of Calvin cycle
produces three carbon 3-PGA
photorespiration
RuBisCo binds with oxygen instead of
CO2 (no ATP or sugar produced)
C4 plants
plants with modified biochemical
pathways to minimize water loss and
maximize sugar production
Gregor Mendel
father of genetics; Austrian monk who
bred garden peas to study patterns of
inheritance
particulate inheritance
inherited characteristics are carried by
discrete units
elemente
Mendel's idea for a gene
gene
sequence of DNA that codes for a
protein and thus determines a trait
probability
likelihood that a particular event will
happen
law of dominance
law stating that when two organisms
homozygous for two opposing traits are
crossed, the hybrid offspring will exhibit
only the dominant trait
homozygous
carry identical alleles
heterozygous
carry different alleles
hybrid
offspring of a cross between two
opposing homozygous
dominant trait
trait that shows in a hybrid
recessive trait
trait that is masked in a hybrid
law of segregation
law stating that during the formation of
gametes, the two alleles carried by each
parent separate
monohybrid cross
cross between two hybrids for a single
trait
phenotype
appearance
genotype
genetic makeup
testcross (or backcross)
cross between an organism exhibiting
the dominant trait and a homozygous
recessive to determine the genotype of
that organism
law of independent
law stating that during gamete
assortment
formation, the alleles of a gene for one
trait segregate independently from the
alleles of a gene for another trait
dihybrid cross
cross between two individuals hybrid for
two or more traits
segregate
assort (in terms of chromosomes during
meiosis)
incomplete dominance
heterozygous expresses a blend of both
alleles
codominance
heterozygous expresses both alleles
multiple alleles
more than two allelic forms of a gene
pleiotropy
ability of one single gene to affect an
organism in several ways
cystic fibrosis
autosomal recessive disorder caused by
a defect in CFTR membrane protein;
results in buildup of mucus in the lungs,
digestive tract, etc.; common in
Caucasians
epistasis
two genes control a trait, but one gene
masks the expression of the other gene
polygenic trait
trait that results from a blending of
several separate genes that vary along a
continuum resulting in a bell curve
genomic imprinting
variation in phenotype depending on
whether a trait is inherited from the
mother or from the father; caused by
silencing of a particular allele by
methylation of DNA on autosomes;
passed on to all cells on the body
extranuclear genes
genes located in mitochondria and
chloroplasts; DNA is small, circular, and
contains few genes
multifactorial basis
underlying genetic component with a
significant environmental influence
nurture and nature
interaction of genetic predisposition and
environment
penetrance
proportion of individuals in a group with
a given genotype that actually shows the
expected phenotype
linked genes
genes on the same chromosome;
inherited together unless separated by
crossing-over
autosome
not sex chromosome
sex chromosome
chromosome that determines sex; X or Y
sex-linked trait
trait carried on the X chromosome
carrier (genetics)
female carrying only one mutated Xlinked gene
recombination
a combining of genes or characters
different from what they were in the
parents due to crossing-over
map unit
distance within which recombination
occurs 1 percent of the time
recombination
how often recombination occurs
frequency
between two linked genes
linkage map
map showing the order of genes on a
chromosome based on recombination
frequencies
pedigree
family tree that indicates the phenotype
of one trait being studied for every
member of a family
somatic cell
body cell
genetic mosaic
in a female embryo, some cells have one
X activated others have the other X
activated
Barr body
inactivated X chromosome condensed
into a dark spot of chromatin seen at the
outer edge of the nucleus of all somatic
cells in females
mutation
change in the genome
gene mutation
change in the DNA sequence
chromosome mutation
change in structure or number of
chromosomes
karyotype
procedure showing the size, number,
and shape of chromosomes to reveal
the presence of chromosomal mutations
phenylketonuria
autosomal recessive disease resulting in
the inability to break down the amino
acid phenylalanine
Tay-Sachs disease
autosomal recessive disease caused by
the lack of the enzyme necessary to
break down lipids needed for normal
brain function; common in Ashkenazi
Jews; results in seizure, blindness, death
Huntington's disease
autosomal dominant degenerate disease
of the nervous system resulting in certain
and early death; onset around middle
age
hemophilia
sex-linked recessive disorder caused by
the absence of one or more proteins
necessary for normal blood clotting
color blindness
sex-linked recessive disorder that impairs
ability to distinguish colors; commonly
red-green color blindness
Duchenne muscular
sex-linked recessive disorder resulting in
dystrophy
progressive weakening of muscle
control and loss of coordination
sickle cell disease
autosomal recessive disorder caused by
a mutation in the gene for hemoglobin
(glutamic acid to valine); results in
deformed red blood cells; carriers are
resistant to malaria
Down syndrome
caused by trisomy 21; results in
characteristic facial features, mental
retardation, prone to Alzheimer's and
leukemia
Turner's syndrome
caused by a missing X chromosome in
females; small stature, sterile
Klinefelter's syndrome
caused by extra X chromosome in males;
sterile, abnormally small testes
deletion (chromosomal)
chromosomal mutation - chromosomal
fragment lacking a centromere is lost
during cell division
inversion
chromosomal mutation - chromosomal
fragment reattaches to its original
chromosome in the reverse orientation
translocation
chromosomal mutation - chromosomal
(chromosome)
fragment attaches to nonhomologous
chromosome
polyploidy
organism has extra set(s) of
chromosomes
nondisjunction
chromosomal mutation - homologous
chromosomes fail to separate during
meiosis
aneuploidy
abnormal number of chromosomes
trisomy
chromosome present in triplicate (e.g.
trisomy 21)
tetraploid
four sets of chromosomes
octoploid
eight sets of chromosomes (e.g.
strawberries)
triploid
three sets of chromosomes (e.g. cancer
cells)
polyploid
organism with extra sets of
chromosomes
Frederick Griffith
discovered that bacteria have the ability
to transform harmless cells into virulent
ones by transferring some genetic factor
from one bacteria cell to another
bacterial transformation
ability for bacteria to change harmless
cells into virulent ones by transferring
some genetic factor from one bacteria
cell to another
transformation
Griffith's experiment on transformation
experiment
and strains of the bacteria that causes
pneumonia
Oswald Avery,
discovered that the transforming factor
MacLeod, McCarty
is DNA
Alfred Hershey and
research supported the theory that DNA
Martha Chase
is the genetic material
Rosalind Franklin
took the X-ray crystallography photo of
DNA that showed its double helix shape
James Watson and
proposed the double helix model for
Francis Crick
DNA with two antiparallel,
complementary strands
Matthew Meselson and
proved that DNA replicates in a
Franklin Stahl
semiconservative fashion
double helix
shape of a twisted ladder
antiparallel
two strands of DNA run in opposite
directions
deoxyribose
5-carbon sugar forming the backbone
for DNA
adenine
purine nitrogenous base that bonds by a
double hydrogen bond to thymine
guanine
purine nitrogenous base that bonds by a
triple hydrogen bond to cytosine
cytosine
pyrimidine nitrogenous base that bonds
by a triple hydrogen bond to guanine
thymine
pyrimidine nitrogenous base that bonds
by double hydrogen bond to adenine
(DNA)
histone
proteins that are combined with DNA in
chromosomes
chromatin
complex of DNA and histones
nucleosome
parts of a chromosome formed when
DNA wraps twice around a pair of
histones
ribose
5-carbon sugar forming the backbone
of RNA
uracil
pyrimidine nitrogenous base that bonds
by a double hydrogen bond to adenine
(RNA)
semiconservative
each strand serves as a template for the
replication
formation of a new complementary
strand
template
one strand of DNA can "build" another
strand using complementary base
pairing
origin of replication
special site where replication begins
replication bubble
where DNA replication is actively
occuring
replication fork
Y-shaped region where the new strands
of DNA are elongating
DNA polymerase
catalyzes the antiparallel elongation of
the new DNA strands
RNA primer
pre-existing chain made of RNA to
which DNA nucleotides are added
primase
enzyme that makes the primer by joining
together RNA nucleotides
leading strand
strand formed toward the replication
fork in an unbroken, linear fashion
lagging strand
strand formed away from the replication
fork into a segmented approach
Okazaki fragments
DNA fragments involved in the synthesis
of the lagging strand, 100-200
nucleotides long, that is later all
connected by ligase
DNA ligase
enzyme that joins Okasaki fragments into
a continuous strand of DNA
helicase
enzyme that untwists the double helix
single-strand binding
protein that holds strands apart, acts as
protein
a scaffolding
topoisomerase
lessens the tension on the tightly wound
helix by breaking, swiveling, and
rejoining the DNA strands
mismatch repair
proofreading carried out by DNA
polymerase that corrects errors in
replication
DNA nuclease
excises damaged regions of DNA during
replication
telomere
protective end of eukaryotic
chromosome with repetitive nonsense
nucleotide sequence to protect against
loss of genes
telomerase
creates and maintains telomeres
triplet code
DNA read in groups of three
nucleotides; each indirectly code for
amino acid
codon
mRNA read in groups of three
nucleotides; each code for amino acid
anticodon
tRNA three nucleotides complementary
to mRNA codon
transcription
information in a DNA sequence copied
into a complementary RNA sequence
messenger RNA
RNA involved in transcription and
translation
ribosomal RNA
structural RNA involved in translation
transfer RNA
functional RNA carrying amino acids to
mRNA at ribosome
initiation (transcription)
RNA polymerase recognizes and binds
to DNA at the promoter region
RNA polymerase
pries the two strands of DNA apart and
attaches RNA nucleotides according to
base pairing rules
promoter
signals RNA polymerase where to begin
transcription and which of the two
strands to transcribe
transcription factor
protein that recognizes the TATA box
and mediates the binding of RNA
polymerase to the DNA
TATA box
key area within the promoter with
repeating thymine and adenine
nucleotides
transcription initiation
completed assembly of transcription
complex
factors and RNA polymerase bound to
the promoter
elongation
RNA polymerase adds nucleotides to
(transcription)
the 3' end of a growing RNA chain
transcription unit
stretch of DNA transcribed into an
mRNA molecule
termination
(transcription)
final stage of transcription during which
RNA polymerase finishes transcribing
and the mRNA is cut free from the DNA
template
termination sequence
signals RNA polymerase to end
transcription; AAUAAA
RNA processing
mRNA altered by a series of enzymes
before shipped out the nucleus to
ribosome
5' cap
helps mRNA bind to ribosome during
translation; consists of modified guanine
nucleotide
poly-A tail
protects RNA strand from degradation
by hydrolytic enzymes and facilitates the
release of mRNA from the nucleus into
the cytoplasm; consists of a string of
adenine nucleotides
intron
intervening, non-coding sequence that is
removed from the mRNA
splice
remove introns from mRNA
small nuclear
proteins that splice introns from mRNA
ribonucleoproteins
splicesomes
structure in eukaryotic nuclei that are
where mRNA splicing takes place
exon
expressed sequence that is not spliced
out from mRNA
primary transcript
mRNA before splicing
final transcript
mRNA after splicing
alternative RNA splicing
different RNA molecules produced from
same primary transcript, depending on
which RNA segments treated as exons
and which as introns; controlled by
regulatory proteins specific to cell type
that bind to regulatory sequences on
primary transcript
translation
process by which the codons of an
mRNA sequence are changed into an
amino acid sequence
guanosine triphosphate
provides the energy for translation
aminoacyl-tRNA
joins amino acids to the correct tRNA;
synthetase
one for each amino acid
start codon
signals where translation starts; AUG codes for methionine
stop codon
terminates translation; UAA, UAG, UGA
wobble
relaxation of base pairing rules for the
third base due to redundancy of genetic
code
initiation (translation)
mRNA attached to a subunit of
ribosome; start codon must be position
correctly for translation to begin
elongation (translation)
tRNA brings amino acids to ribosome
and a polypeptide chain formed
polyribosome
cluster of ribosomes simultaneously
translating a mRNA molecule
termination (translation)
polypeptide freed from ribosome when
stop codon reached
release factor
factor that breaks the bond between the
tRNA and the last amino acid of the
polypeptide chain
genetic code
redundant, inambiguous table showing
which amino acid each codon codes for
mutagenic agent
cause mutations (e.g. toxins, radiation)
gene pool
all the genes in a population
point mutation
simplest mutation at a single base pair in
a single gene
base-pair substitution
change in just one base pair of a single
gene
insertion
nucleotide added into DNA sequence
deletion (gene)
nucleotide taken away from DNA
sequence
frameshift mutation
mutations that shift the reading frame of
the DNA triplets because of insertions
and deletions
missense mutation
a nucleotide-pair substitution that results
in a codon that codes for a different
amino acid
nonsense mutation
subsitution of wrong nucleotide into
DNA that produces an early stop codon
virus
parasite that can live only inside another
cell; infects a cell for reproduction;
consists of DNA or RNA genome
enclosed in protein coat
capsid
protein coat of virus
viral envelope
structure derived from membrane of
host cells that cloaks the capsid and aids
the virus in infecting host
host range
range of organisms that a virus can
attack because requires specific
receptors to attach
bacteriophage
virus that infects bacteria
lytic cycle
phage enters host cell, immediately
replicates itself, and bursts the cell to
release new phage viruses
virulent phage
phage that reproduces solely by lytic
cycle
lysogenic cycle
phage virus incorporated into host
bacterial DNA and carries on to
offspring
prophage
viral genes inserted but dormant within
the host genome
lytic phase
phase of lysogenic cycle in which
environment trigger causes prophage to
"reveal" itself and start reproducing
temperature virus
virus capable of lytic and lysogenic
reproduction
retrovirus
virus that contain RNA instead of DNA
and convert RNA to complementary
DNA to insert into host genome
reverse transcriptase
synthesizes complementary DNA from
RNA for insertion into host genome in
retroviruses
nucleoid
region of bacteria that contains the
bacterial chromosome
transduction (bacteria)
phage viruses cause genetic
recombination because acquire bits of
bacterial DNA from infecting so many
cells
generalized
moves random pieces of bacterial DNA
transduction
as phage lyses cells
restricted transduction
prophage carries piece of adjacent
bacterial DNA when lyses cell and
inserts this into next host
binary fission
efficient asexual bacterial reproduction
plasmid
foreign, small, circular, self-replicating
DNA molecule that inhabits a bacterium
F plasmid
first plasmid discovered; for fertility
pilus
cytoplasmic bridge that connects
adjacent bacterial cells for conjugation
to take place
conjugation
plasmid from one bacterium moves to
another; primitive sexual reproduction
R plasmid
plasmid for antibiotic resistance
operon
set of genes and switches that control
expression of those genes
Jacob and Monod
discovered the operon model in E. coli
gene regulation
process of controlling which genes
expressed
repressible operon
always switched on unless repressor
activated
tryptophan operon
repressible operon with a promoter and
five structural genes that code for five
enzymes to synthesize amino acid
tryptophan
corepressor
activates the repressor
repressor
when activated, binds to the operator to
prevent RNA polymerase from binding
to the promoter
operator
region on operon that binds repressor to
prevent RNA polymerase from binding
to the promoter
inducible operon
always switched off unless repressor
inactivated
inducer
binds to the repressor to inactivate it
positive gene
attachment of molecule (e.g. cAMP) to
regulation
promoter directly stimulates gene
expression
regulator gene
gene that codes for a repressor; located
away from operon and has own
promoter
scrapie
fatal disease in sheep caused by prions
mad cow disease
fatal disease in cattle caused by prions
Creutzfeldt-Jakob
fatal disease in humans caused by prions
disease
tandem repeat
back-to-back repetitive sequence within
genes that cause genetic disorders or
make up telomeres
polymorphic region
certain noncoding regions of DNA that
are highly variable from one region to
the next
acetylation
adding acetyl group to histone tails
promotes loosening of chromatin
structure and permits transcription
methylation
adding methyl groups to DNA silences
DNA temporarily or for long periods of
time (e.g. long-term X chromosome
deactivation); causes genomic imprinting
epigenetic inheritance
reversible alternations to the genome
that do not directly involve the
nucleotide sequence but are caused by
environmental factors
degradation of mRNA
mRNA broken down after translation
with varying amount of time
noncoding RNA
transcribed from non-protein-coding
DNA; regulate much of DNA
Argonaute protein
protein that binds to and assists
noncoding RNA
microRNA
single-stranded RNA about 22
nucleotides long, forms a complex with
proteins, targets specific mRNA
molecules for degradation or blocking
of translation (mi)
small interfering RNA
single-stranded RNA about 22
nucleotides long, forms a complex with
proteins, targets specific mRNA
molecules for degradation or blocking
of translation (si)
RNA interference
blocking of gene expression by siRNA
piwi-associated RNA
guide PIWI proteins to complementary
RNAs derived from transposable
elements; protect germ line cells from
attack by transposons
recombinant DNA
DNA taken from multiple sources and
combined into single molecule
transposon
jumping genes that move around the
genome
recombinant DNA
techniques used to create recombinant
techniques
DNA in biotechnology
biotechnology (genetic
branch of science that uses recombinant
engineering)
DNA techniques for practical purposes
gene therapy
replace a nonfunctioning gene in a
person's cells with a functioning gene
vector
means of inserting a gene into a cell
competent (bacteria)
bacterium able to take up a plasmid
gene cloning
as bacteria reproduce, gene copied
(biotechnology)
restriction enzyme
enzymes extracted from bacteria that
cut DNA at specific recognition
sequences
recognition sequence
sequence on DNA where restriction
enzymes cut
sticky end
single-stranded end of DNA formed by
staggered restriction enzyme cut
restriction fragment
fragment that results from the cuts made
by restriction enzymes
EcoRI
restriction enzyme discovered in E. coli G/AATTC
BamHI
restriction enzyme discovered in B.
amyloliquefaciens G/GATCC
HindIII
restriction enzyme discovered in H.
influenzae - A/AGCTT
gel electrophoresis
recombinant DNA technique used to
separate large molecules of DNA
agarose gel
a gel matrix used for electrophoresis
cathode
negative terminal in gel electrophoresis;
DNA molecules travel away
anode
positive terminal in gel electrophoresis;
DNA molecules travel towards
DNA sequencing
biotechnology technique that
determines order of nucleotides in a
gene
DNA probe
radioactively labeled single strand of
nucleic acid molecule used to tag a
specific sequence in a DNA sample
polymerase chain
cell-free, automated technique by which
reaction
a piece of DNA can be rapidly copied or
amplified
Taq polymerase
heat-stable form of DNA polymerase
extracted from thermophile bacteria
restriction fragment
differences in restriction fragment
length polymorphism
pattern in noncoding regions of DNA
DNA fingerprint
restriction fragment length
polymorphism analysis of someone's
DNA
paternity suit
determine if a particular man is the
father of a particular child using
restriction fragment length
polymorphism
CRISPR
clustered regularly interspersed short
palindromic repeats; genetic
engineering tool made of RNA that can
be guided by the enzyme Cas9 to
modify a target stretch of DNA
DNA chip
chip that holds personal information
about someone's genetic makeup,
including mutations that have a
predisposition to cancer
taxonomy
naming and classification of species
binomial nomenclature
two-part name for every organism
Linnaean classification
hierarchial classification of species into
broader groups of organisms (kingdom > species)
taxon
broad group of organisms, ranging from
kingdom to species
kingdom
the uppermost level of Linnaean
classification, reflects very basic
differences
phylum
subdivision of kingdom, group of classes
class
subdivision of phylum, group of orders
order
subdivision of class, group of families
family
subdivision of order, group of genera
genus
subdivision of family, group of species
species
lowermost level of Linnaean
classification; group of organisms that
can interbreed and produce fertile
offspring
phylogeny
evolutionary history
three-domain system
modern classification system based on
DNA analysis that accurately reflects
phylogenetic relationships and groups
organisms into three main domains
Domain Bacteria
domain of prokaryotic organisms with
cell wall of peptidoglycan
Domain Archaea
domain of prokaryotic organisms with
cell wall without peptidoglycan
Domain Eukarya
domain of eukaryotic organisms
Kingdom Monera
old term used to group together all
prokaryotes (Bacteria and Archaea)
decomposer
ecological niche of recycling dead
organic matter
pathogen
disease-causing organism
peptidoglycan
polymer of amino acids and sugars that
forms bacterial cell walls
extremophile
organism that lives in an extreme
environment
methanogen
obtains energy by producing methane
from hydrogen
halophile
thrive in environments with high salt
concentration
thermophile
thrive in very high temperatures
systematics
modern-day taxonomy that considers
biological diversity in an evolutionary
and ancestral context
Kingdom Protista
eukaryotic kingdom that includes
organisms that don't fit within the other
kingdoms
heterotroph
organism that obtains energy from the
foods it consumes
autotroph
organism that obtains energy from the
foods it synthesizes
protozoa
animal-like protist; heterotroph that
moves independently
amoeba
protozoa that moves by psuedopods
paramecium
protozoa that moves by cilia
euglena
protozoa that moves by flagella;
primarily autotrophic with red eyespot
and chlorophyll for photosynthesis but
can be heterotrophic and still protozoa
amoebic dysentery
disease caused by the species
Entamoeba histolytica
malaria
fatal, tropical disease caused by
Plasmodium protozoa and is transferred
by mosquito bites
Kingdom Fungi
kingdom of eukaryotes that are
heterotrophic and have a cell wall of
chitin
absorptive nutrition
fungal method of consumption in which
the fungus secretes hydrolytic enzymes
outside the body where extracellular
digestion occurs, then the building
blocks of the nutrients are absorbed into
the body of the fungus by diffusion
Kingdom Plantae
kingdom of eukaryotes that are
autotrophic and have cell walls of
cellulose
athlete's foot
fungal infection usually in the skin of the
toes and soles
tracheophyte
plant with vascular tissue
bryophyte
plant without vascular tissue
Kingdom Animalia
kingdom of multicellular eukaryotes that
lack cell walls and are heterotrophs
monophyletic
all lineages can be traced back to one
common ancestor
multicellular
consisting of multiple cells; came about
1.5 bya
radial symmetry
a body plan in which the parts of an
animal's body are organized in a circle
around a central axis; found in Cnidaria
and Echinodermata
bilateral symmetry
body plan in which only a single line of
symmetry can divide the body into two
equal halves; found in worms, mollusks,
arthropods, and chordates
cell
basic unit of all forms of life
tissue
group of similar cells that perform a
particular function
organ
group of tissues that work together to
perform related functions
triploblastic
consisting of three germ layers during
embryonic development
ectoderm
outermost germ layer that becomes the
skin and nervous system
endoderm
innermost germ layer that becomes the
digestive system
mesoderm
middle germ layer that becomes the
blood and bones
diploblastic
consisting of two germ layer during
embryonic development
mesoglea
middle glue connecting ectoderm and
endoderm in diploblasts
longitudinal axis
line of symmetry running through
bilateral symmetry animals
anterior
front end
posterior
rear end
cephalization
development of a head end
Phylum Porifera
phylum of animals without true tissue
Phylum Cnidaria
phylum of animals with true, simple
tissue but only 2 germ layers
Phylum Platyhelminthes
phylum of animals with organs but no
organ systems
Phylum Annelida
phylum of animals with organ systems
Phylum Arthropoda
phylum of animals with organ systems
phylogenetic tree
diagrammatic reconstruction of
organism's phylogony (p)
cladogram
diagrammatic reconstruction of
organism's phylogony (c)
maximum parsimony
principle used to narrow down
possibilities when constructing
cladogram, states that one should follow
the simplest explanation that coincides
with the facts
ingroup
organism of interest when constructing
cladogram
outgroup
organism as a point of reference when
constructing cladogram
node
point where two lineages diverge on
cladogram
shared ancestral
character that all organisms in a lineage
character
share
clade
lineage that includes organisms and their
common ancestor
shared derived
new trait of a clade that distinguishes it
character
from other clades
evolution
change in allelic frequencies in a
population
funny duck
kanav!!!!!! Ha! Ha! Ha!
sedimentary rock layer
layer that contains sedimentary rock of
different ages and can contain fossils
relative age
measurement of age of rocks and fossils
based on the location in the sedimentary
rock layers
absolute age
precise measurement of age of rocks
and fossils
radiometric dating
use decay of radioactive isotopes and
half-life to measure absolute age
paleomagnetic dating
use the shifts and reverses of Earth's
magnetic poles to measure absolute age
cyanobacteria
oxygen-generating, photosynthetic
bacteria that provided free oxygen for
the oceans and atmosphere during early
Earth
stromatolite
rocklike structure formed by
cyanobacteria
Cambrian explosion
relatively short period 535-525 mya
characterized by the sudden
appearance of many modern animal
phyla
fossil record
collection of all the fossils through the
ages; reveals ancestral and extinct
species
Eohippus
an early ancestor to the modern horse
Equus
transitional form between Eohippus and
modern horses
Archaeopteryx
an intermediate fossil that shows both
reptile and bird characteristics
comparative anatomy
study of different structures across
species
homologous structure
structures that have common structure
so reflect a common ancestry
analogous structure
structures that have common function so
reflect an adaptation to similar
environment
vestigial structure
structure that is no longer needed but
reflects how structures and behaviors
have evolved
comparative
study of common biochemical pathways
biochemistry
among species
cytochrome c
electron carrier protein in electron
transport chain of cellular respiration
and photosynthesis, present in all
aerobic organisms so its amino acid
sequence can be used to determine
phylogenetic relationships
comparative
study of similar stages in embryonic
embryology
development among species
biogeography
study of past and present geographic
distribution of organisms
plate tectonics
continents and oceans rest on giant
plates of Earth's crust floating on top of
the mantle
mantle
hot, middle layer of the Earth
continental drift
slow, continuous movement of plates
caused by convection currents in the
mantle
Pangaea
supercontinent formed from all land
mass in the world around 250 mya
marsupial
one of a family of mammals that nurse
their offspring in a pouch
eutherian
true placental mammal
Aristotle
theorized that all life-forms can be
arranged in order of complexity with
humans at the top and that species do
not evolve
Carolus Linnaeus
developed classification system
Georges Cuvier
studied fossils and realized that each
stratum of Earth is characterized by
different fossils
catastrophism
theory that a series of events in the past
occurred suddenly and were caused by
mechanisms different from those
operating in the present
James Hutton
geologists who came up with gradualism
and that Earth was very old and had
changed much
gradualism (geology)
theory that Earth has been molded by
slow, gradual change and by the same
forces as in the present
Charles Lyell
geologist who stated that geological
change results from slow, continuous
actions
Jean-Baptiste Lamarck
developed an earlier theory of evolution
about acquired characteristics and
use/disuse
inheritance of acquired
organisms can pass on traits that they
characteristics
acquired over their lifetime to offspring
use and disuse
organisms develop or remove structures
in response to their environment
Alfred Russel Wallace
theorized a similar idea about natural
selection around the same time as
Darwin
Charles Darwin
naturalist and author who came up with
the mechanism behind evolution
theory of natural
Darwin's major theory stating that
selection
1) Populations tend to overpopulate and
exceed resources.
2) Overpopulation results in a struggle
for existence.
3) Variation exists in a population, and
there is an unequal fitness for individuals.
4) The best-fit individuals survive and
pass traits to offspring.
5) Evolution occurs as advantageous
traits accumulate in a population
descent with
Darwin's principle that each living
modification
species has descended, with changes,
from other species over time
On the Origin of
Darwin's book about natural selection
Species
and descent with modification
Thomas Malthus
published treatise on population growth,
war, disease, and famine
fitness
ability for organism to survive and
reproduce living offspring
selective advantage
advantage given by environmental
pressures
stabilizing selection
selection that eliminates extreme
phenotypes and favors intermediate
disruptive selection
selection that favors extreme
phenotypes and eliminates intermediate
balanced
division of one population into two
polymorphism
distinct phenotypes, caused by
disruptive selection, may lead to
speciation
directional selection
selection that favors one extreme and
eliminates the other extreme and
intermediate; replaces the most
dominant phenotype with another in the
genepool
industrial melanism
darkening of populations of organisms
over time in response to industrial
pollution
peppered moths
classic example of directional selection
in which a white population turned to
black due to directional selection for
black moths to blend in with the
polluted environment
antibiotic
chemical that kills bacteria
antibiotic resistance
resistance to antibiotics caused by
mutation and carried by plasmids; can
evolve quickly in bacterial populations
sexual selection
selection based on variation in
secondary sexual characteristics related
to competing for and attracting mates
sexual dimorphism
differences in appearance between
males and females
artificial selection
human breeding of plants and animals
by seeking individuals with desired traits
as breeding stock
morph
variety of organism in balanced
polymorphism due to disruptive
selection
cline
graded, regional variation in the
phenotype of an organism
north-south cline
cline that exists because of differences
in phenotype in northern and southern
environments
sexual reproduction
reproduction involving cells from two
parents uniting to form the first cell of a
new organism; increases genetic
diversity
asexual reproduction
reproduction involving a single parent;
very efficient and rapid
outbreeding
mating of organisms within one species
that are not closely related; increases
genetic variation
inbreeding
mating of organisms within one species
that are closely related; weakens gene
pool
diploidy
the 2n condition that maintains and hides
a huge pool of alleles that may be
presently harmful but advantageous in
the future
heterozygote
hybrid individual selected for because
advantage
greater reproductive success against
homozygotes; preserves multiple alleles
in population
frequency-dependent
minority phenotypes are selected for
selection (minority
and frequency increases; frequency of
advantage)
more common phenotypes decreases;
often acts in a cycle
evolutionary neutral
traits that seem to have no selective
traits
advantage
blood type
type of blood determined by antigens
on red blood cells
genetic drift
change in the gene pool due to chance;
fluctuation in frequency of alleles from
one generation to another
bottleneck effect
genetic drift occurring after a natural
disaster which reduces population size
and genetic variation; certain alleles may
be overrepresented or
underrepresented compared with
original population
founder effect
genetic drift occurring when a small
population breaks away from a larger
one to colonize a new area; small
population gene pool likely not
representative of the large population
polydactyly
condition of having extra fingers and
toes; common in Pennsylvanian Amish
due to the founder effect
gene flow
movement of alleles into or out of a
population as a result of migration of
individuals/gametes
Hardy and Weinberg
scientists who came up with namesake
equation and equilibrium for evolution
genetic equilibrium
allelic frequencies not changing, so no
evolution. Factors include
1) Large popl
2) Isolated
3) No mutation
4) Random mating
5) Natl selection
Hardy-Weinberg
equation that enables us to calculate
equation
frequencies of alleles in a population in
genetic equilibrium
p
letter for dominant allele
q
letter for recessive allele
p+q=1
equation stating frequencies of
dominant and recessive allele
p^2 + 2pq + q^2 = 1
equation stating percentages of
homozygous dom, heterozygous, and
homozygous rec
reproductive isolation
one group of genes becomes isolated
from another to begin a separate
evolutionary history
speciation
formation of new species caused by
reproductive isolation and evolutionary
differences over time
allopatric speciation
speciation caused by geographic
isolation
geographic isolation
isolation caused by separation by
mountains, canyons, rivers, lakes,
glaciers, altitude, or longitude
sympatric speciation
speciation not caused by geographic
isolation
polyploidy (evol)
the number of chromosomes of
individuals determines if interbreeding is
possible (only if chromosome number
the same)
habitat isolation
isolation that occurs when two
organisms live in the same area but
encounter each other rarely
behavioral isolation
isolation resulting from behavioral
patterns, like mating dances
temporal isolation
isolation resulting from breeding during
different times
prezygotic barrier
barrier that prevents mating (e.g.
difference in genital structure)
postzygotic barrier
barrier that prevent production of fertile
offspring after mating
divergent evolution
population becomes isolated from the
rest of the species and when exposed to
new selective pressures, evolves
adaptations to diverge from common
ancestor (types include
allopatric/sympatric speciation)
convergent evolution
two unrelated species evolve similar
adaptations due to similar environmental
pressures
parallel evolution
two related species have made similar
evolutionary adaptations after
divergence from common ancestor
coevolution
reciprocal evolutionary set of
adaptations of two interacting species
monarch butterfly
butterfly that lays its eggs in the
milkweed plant
milkweed plant
plant that is home to monarch larvae
and produces poisons
adaptive radiation
emergence of numerous species from a
common ancestor introduced into an
environment in order to fill specialized
ecological niches
Darwin's finches
birds studied by "Darwin's" that evolved
from single ancestral species and by
adaptive radiation, evolved into 14
species
Galapagos islands
islands on the equator in the Pacific near
Ecuador where Darwin collected his
most important observations
transitional form
fossil that serves as an intermediate
between ancestral and modern species
gradualism
theory that organisms descend from
common ancestor gradually over a long
period of time in a linear or branching
fashion; theory not supported anymore
punctuated equilibrium
favored theory of evolution stating that
new species appear suddenly after long
periods of stasis, can be explained by
allopatric speciation (relying on
geographical events)
Gould and Eldridge
scientists who proposed punctuated
equilibrium
evolutionary
biology that studies how major changes
developmental biology
in body form and function come about
due to changes in regulatory genes
homeotic gene
master regulatory gene that controls
spatial organization of body parts during
embryonic development
Hox gene
homeotic gene providing positional
information in developing embryp
upregulate
increase expression of
downregulate
decrease expression of
heterochrony
evolutionary change in the rate or timing
of development of body parts
axolotl
adult aquatic salamander that retains
gills into adulthood
Oparin and Haldane
scientists to first hypothesize that
organic molecules could form under
conditions of early Earth
Miller and Urey
tested Oparin-Haldane hypothesis and
found that energy source could convert
molecules in early atmosphere to
organic molecules esp. amino acid
Sidney Fox
produced membrane-bound, cell-like
structures called proteinoid
microspheres from organic molecules
heterotroph hypothesis
hypothesis stating that first cells on
Earth were anaerobic heterotrophic
prokaryotes that simply absorbed
organic molecules from the surrounding
primordial soup
RNA World
concept hypothesizing that the small,
single-stranded RNA was the first
genetic substance on Earth
ribozyme
type of RNA that catalyzes reactions like
enzymes do while still retaining genetic
material
exaptation
traits that evolve by natural selection in
one context but are then co-opted for
another purpose
root
structure of plant that absorbs
water/nutrients from the soil
root hair
structure on root that increases surface
area for maximum uptake
vascular tissue
tissue of xylem and phloem that moves
fluid great distances
stoma
opening on underside of leaf to
exchange photosynthetic gases
cutin
waxy coating on the leaves to prevent
excess water loss
gametanglia
protective jacket of cells that prevents
gametes and zygotes from drying out
sporopollenin
tough polymer resistant to
environmental damage found in walls of
spore and pollen
seed
structure that can grow a new plant in
gymnosperms and angiosperms
pollen
small grains that act as means of
fertilization using dispersion
lignin
complex polymer that hardens cell walls
of some vascular tissues in plants esp.
xylem
mychorrhizae
type of fungus that live in plant roots
that form a symbiotic relationship with
plants - mychorrhizae enhance uptake
of nutrients and water, mychorrhizae get
carbohydrates from plant
guard cell
modified epidermal cell that control the
opening of the stomates using osmotic
pressure
flaccid
plant cell that has lost water
translocation (plants)
process by which phloem travels
throughout the plant, requires input of
energy to load sugar into phloem
phloem
vascular tissue that transports sugar
throughout the plant
xylem
vascular tissue that transports water and
minerals throughout the plant without
using energy
root pressure
pressure that results from water flowing
into the stele from the soil a a result of
the high mineral content in the cells
guttation
droplets of water appearing on tips of
leaves due to root pressure
auxin
plant hormone that is responsible for
phototropisms, apical dominance, and
root development
cytokinin
plant hormone that stimulates cell
division and delays senescence; sprayed
on flowers for freshness
gibberellin
plant hormone promoting stem and leaf
elongation and "bolting" (rapid growth
of floral stalk)
abscisic acid
plant hormone that promotes seed
dormancy, enables drougtht to survive
drought, and close stomata for water
conservation
ethylene gas
plant hormone that promotes ripening
tropism
growth of a plant toward or away from a
stimulus
thigmotropism
tropism based on touch
geotropism
tropism based on gravity; results from
(gravitotropism)
auxins and stalothiths
phototropism
tropism based on light; results from
auxin accumulation on the side of the
plant away from the light
positive tropism
growth of a plant toward a stimulus
negative tropism
growth of a plant away from a stimulus
statolith
specialized plastid containing dense
starch grains
photoperiod
relative lengths of day and night that a
plant uses to detect the time of year
based on environmental stimuli
circadian rhythm
biological clock set to a 24-hour day
photoperiodism
physiological response to the
photoperiod
long-day plants
plants that will only flower when light
longer than certain number of hours
short-day plants
plants that will only flower when light
shorter than a certain number of hours
day-neutral plants
plants that will flower regardless to the
length of day
phytochrome
photoreceptor responsible for keeping
the track of the length of day and night
red-light absorbing
phytochrome form in which it is
phytochrome
synthesized and is maintained in the dark
infrared light absorbing
phytochrome form maintained during
phytochrome
the day
hydra
type of Cnidarian; small tubular solitary
freshwater hydrozoan polyp
gastrovascular cavity
one-opening cavity in Cnidarians in
which digestion occurs
gastrodermis
lining of the gastrovascular cavity
extracellular digestion
digestion that takes place by secretory
digestive enzymes outside cells and
inside cavities or environment
earthworm
a member of Annelida; terrestrial worm
that burrows into and helps aerate soil
crop
digestive organ where food is stored in
Annelida
gizzard
digestive organ that grinds up food with
help of sand and soil in Annelida
typhlosole
large fold in the upper surface of the
intestine to increase surface area for
maximum absorption in Annelida
grasshopper
member of Arthropoda; terrestrial planteating insect with hind legs adapted for
leaping
digestion
breaking down large food molecules
into smaller usable molecules
absorption
diffusion of smaller, broken down
molecules into body's cells
vitamin
organic molecules that function as
coenzymes; necessary in diet
mineral
inorganic molecules that function as
cofactors; necessary in diet
smooth muscle
muscle whose actions are involuntary
and most often necessary for life
processes; nonstriated
peristalsis
process of moving food along digestive
tract by smooth muscle
tongue
taste organ that helps to move food
around mouth
teeth
cut, tear, and grind food (different
structures) that break food down
mechanically
omnivore
organisms that eats both producers and
consumers
incisor
teeth for cutting
canine
teeth for tearing
molar
teeth for grinding
salivary amylase
enzyme that begins the chemical
breakdown of starch in the mouth
salivary glands
glands that release saliva (digestive juice
with enzymes, mucus, and electrolytes)
epiglottis
flap of cartilage that directs food into
esophagus and away from trachea
pharynx
throat
stomach
digestive organ that churns food
mechanically and secretes gastric juice
that begins the digestion of proteins
gastric juice
the digestive fluid secreted by the
stomach
gastric pit
pit that makes up stomach lining
chief cell
stomach cell that secretes pepsinogen
pepsinogen
inactive form of pepsin that is activated
by acid
pepsin
enzyme in stomach that digests proteins
parietal cell
stomach cell that secretes hydrochloric
acid to keep pH low for digestion and
pepsin activation and to kill
microorganisms
rennin
enzyme in mammalian stomachs that
aids in digestion of protein in milk
lower esophageal
sphincter that keeps food in the stomach
sphincter
from backing up into the esophagus and
burning it
pyloric sphincter
sphincter at the bottom of the stomach
that keeps food in the stomach long
eough for digestion
ulcer
open sore or lesion in the mucous
membrane of the esophagus, stomach,
or duodenum often caused by excessive
acid
Helicobacter pylori
bacterium that can often cause ulcers
duodenum
upper part of the intensine where
digestion completes
bile
emulsifies fats, creating greater surface
area for digestive enzymes
liver
organ that makes bile to break down
fats; also filters poisons and drugs out of
the blood; produces urea
gallbladder
organ that stores and secretes bile
emulsifier
a substance that keeps two incompatible
substances, such as oil and water, mixed
together
peptidase
class of enzyme that breaks down
proteins into amino acidss
trypsin
enzyme from pancreas that breaks down
proteins in small intestine (t)
chymotrypsin
enzyme from pancreas that breaks down
proteins in small intestine (c)
nuclease
enzyme class that hydrolyzes nucleic
acids
lipase
enzyme class from pancreas that breaks
down fats
villi
microscopic, fingerlike projections that
absorb nutrients from digested food in
small intestine
lacteal
small vessel of the lymphatic system in
villi that absorbs fatty acids and glycerol
lymphatic system
organ system consisting of the network
of vessels through which lymph drains
from the tissues into the blood
microvilli
cytoplasmic appendages coming from
each epithelial cell of a villus that further
increases nutrient absorption
small intestine
digestive organ where most digestion
and absorption occurs
large intestine (colon)
digestive organ that removes of
undigested waste, removes excess
water, and produces vitamins
egestion
removal of undigested waste
vitamin production
process by which bacteria in the large
intestine produce coenzymes, like ___ K
constipation
condition in which too much water
reabsorbed from large intestine
diarrhea
condition in which too little water
reabsorbed from large intestine
rectum
end of the gastrointestinal tract where
feces is stored
feces
undigestable waste
anus
opening at the end of the digestive tract
where feces is excreted
gastrin
hormone from stomach wall that
stimulates sustained production of
gastric juice
secretin
hormone from duodenum wall that
stimulates pancreas to release
bicarbonate to neutralize acid in
duodenum
cholecystokinin
hormone from duodenum wall that
stimulates pancreas to release
pancreatic enzymes (peptidase,
nuclease, lipase, etc.) and gallbladder to
release bile into small intestine
sponge
common name for Porifera
external respiratory
surface on which respiration directly
surface
occurs with environment (at skin)
hemoglobin
protein that carries oxygen in blood
crustacean
any mainly aquatic arthropod usually
having a segmented body and chitinous
exoskeleton
internal respiratory
surface on which gas exchange takes
surface
place inside organism
spiracle
the external opening of the trachea in
arthropods
tracheal tube
system of tubes that air travels through
in arthropods
hemocoel
sinus in arthropod where blood and gas
empty out
hemocyanin
protein similar to hemoglobin that uses
copper instead of iron
nasal cavity
entrance for air where it is moistened,
warmed, and filtered
larynx
voice box
trachea
windpipe, connects larynx to bronchi
bronchus
large tubes that each branch into a lung
bronchiole
tiny branches from bronchi and other
bronchioles
alveolus
microscopic air sacs at the end of
bronchioles where diffusion of
respiratory gases occurs
diaphragm
muscle that contracts to increase
volume of chest cavity to draw air in and
relaxes to decrease volume to expel air
medulla oblongata
structure in brain that controls breathing
and sets the rhythm by monitoring pH
levels (indicative of CO2 levels)
carbonic acid
acid formed when carbon dioxide
dissolves in blood
oxyhemoglobin
molecule formed when hemoglobin
combines with four oxygen molecules
fetal hemoglobin
hemoglobin in fetuses that has a greater
affinity for hemoglobin than adult
hemoglobin
plasma
liquid portion of the blood containing
clotting factors, hormones, antibodies,
gases, nutrients, and wastes and
maintains osmotic potential
carbonic acid-
system that continuously converts
bicarbonate ion system
dissolved carbon dioxide between
carbonic acid and bicarbonate ion
(basic) to maintain pH of blood
open circulatory system
circulatory system where blood leaves
vessels to sinuses (e.g. arthropods)
closed circulatory
circulatory system where blood always
system
contained within vessels (e.g. annelids)
erythrocyte
red blood cell that carries
(oxy)hemoglobin, lacks nucleus, formed
in bone marrow and recycled in liver
leukocyte
white blood cell that die fighting
infection or produce antibodies, formed
in bone marrow
thrombocyte
platelet cell fragment, formed in bone
marrow from megakaryocytes; clot
blood
megakaryocyte
precursor cell to thrombocytes/platelets
stem cell
cell that has the potential to differentiate
into other cells
multipotent stem cell
adult stem cells that keep dividing to
replenish supply of short-lived cells, e.g.
erythrocytes
clotting factor
factors released from platelets and
damaged tissue to begin blood clotting
anticlotting factor
factor normally circulating in plasma that
prevents formation of clot
thrombus
blood clot
thromboplastin
major clotting factor that reacts with
calcium ions
prothombrin
protein released by thromboplastin and
calcium ions
plasma protein
inactivated protein circulating in plasma
thombrin
plasma protein activated by prothombrin
fibrinogen
protein released by thrombrin
fibrin
plasma protein activated by thombrin
that creates a blood clot
artery
blood vessel made of thick, elastic,
smooth muscle that carries blood away
from the heart under enormous
pressures
arteriole
branch of artery to capillaries
vein
blood vessel made of thin walls (with
valves to prevent backflow) that carries
blood back to the heart under very little
pressure so requires movement from
skeletal muscle
venule
merger of capillaries that merge into
vein
capillary
thinnest blood vessel that allows for
diffusion of nutrients and wastes
between cells and blood (walls are onecell thick for diffusion)
atrium
heart chamber that receives blood from
the body cells
ventricle
heart chamber that pumps blood out of
the heart
cardiac muscle
striated, involuntary muscle making up
the heart
sinoatrial node
node in right atrium that sets the timing
of the contractions of the heart through
the atrioventricular node, bundle of His,
and Purkinje fibers
pacemaker
colloquial name for sinoatrial node
electrocardiogram
record of the electrical activity of the
heart using electrical impulses from
pacemaker activity
blood pressure
the pressure that is exerted by the blood
against the walls of blood vessels
systole
ventricles contract; higher blood
pressure
diastole
ventricles relax; lower blood pressure
coronary circulation
circulation through the cardiac muscle to
give nutrients/pick up wastes from
muscle cells
renal circulation
circulation through the kidneys for
filtering
hepatic circulation
circulation through the liver for
processing
pulmonary circulation
circulation through the lungs for
oxygenation
systemic circulation
circulation through most of the body
ectotherm
animal that gains most body heat from
environment; low metabolic rate so heat
generation does not have an effect
endotherm
animal that uses metabolic processes
(e.g. cellular respiration) to produce
body heat at a constant temperature
poikilotherm
animal that has a body temperature that
varies with the environment
homeotherm
animal that has a constant body
temperature despite fluctuations in
environmental temperature
torpor
extreme mental and physical
sluggishness
estivation
state of reduced metabolism that occurs
in animals living in conditions of intense
heat
hibernation
the deep sleeplike torpor that an animal
enters for most of the winter
countercurrent heat
countercurrent exchange used to help
exchange
warm or coll extremities
osmoregulation
management of the body's water and
solute concentration
flame cell
excretory structure of Platyhelminthes
nephridium
excretory structure of Annelida
(metanephridium)
Malphigian tubule
excretory structure of Arthropoda
nephron
functional unit of the kidney
excretion
removal of metabolic wastes
carbon dioxide, water
wastes from cellular respiration
nitrogenous waste
waste from protein metabolism
ammonia
highly toxic and soluble nitrogenous
waste excreted by marine organisms
urea
not very toxic, excreted by earthworms
and humans, formed in liver
uric acid
pastelike substance not soluble or toxic,
excreted by insects, reptiles, birds for
minimal water loss
renal artery
artery to the kidney
renal vein
vein away from the kidney
hyposmotic
dilute
hyperosmotic
concentrated
glomerulus
cluster of capillaries from renal artery
that is next to the nephron
Bowman's capsule
cuplike structure around glomerulus
where filtration occurs
renal tubule
tube that travels through the nephron
filtration
blood pressure forces fluid from the
glomerulus into the Bowman's capsule,
filtering it - passive, nonselective
podocyte
specialized cells of Bowman's capsule
that increase rate of filtration
slit pore
pore in Bowman's capsule that helps
with filtration
proximal convoluted
twisted-up tube close to glomerulus that
tubule
functions in secretion and reabsorption,
secretes ammonia to neutralize acidic
filtrate
secretion
active, selective uptake of certain drugs
and toxic molecules that did not get
filtered into Bowman's capsule
distal convoluted
twisted-up tube far from glomerulus that
tubule
functions in secretion and reabsorption,
aldosterone here
reabsorption
most of the water and solutes that
initially entered renal tubule during
filtration are transported back into
capillaries into body
peritubular capillary
capillary that collects reabsorbed
material from nephron
loop of Henle
structure that moves salts from the
filtrate to accumulate them in the
medulla to build a steep gradient around
the loop (longer loop, greater
reabsorption)
ureter
tube from kidney to bladder
urinary bladder
stores urine till excretion
urethra
tube that excretes urine
aldosterone
hormone produced, stored, and
released by adrenal glands in response
to decreased blood pressure/volume;
acts on distal tubule to reabsorb sodium
ions and water
antidiuretic hormone
hormone produced by hypothalamus
(ADH)
and stored and released by posterior
pituitary in response to dehydration
which causes blood osmolarity to
increases; increases permeability of
collecting duct to water through renal
aquaporin to reabsorb water
renal aquaporin
transmembrane protein that functions as
water channel in the collecting tube
renin
hormone released by kidney that
activates angiotensin to stimulate
adrenal cortex to release aldosterone
diuretic
drug that reduces blood volume by
increasing amount of water in urine
angiotensin-converting
drug that prevents formation of
enzyme inhibitor
angiotensin II and thereby, aldosterone
skeletal muscle
large, multinucleate, striated muscle that
work in pairs
muscle fiber
individual cylindrical muscle cell
sarcolemma
modified plasma membrane that
surrounds muscle fibers and can
propagate an action potential
sarcoplasmic reticulum
modified endoplasmic reticulum that
contains sacs of calcium ions necessary
for normal muscle contraction
T system
system of tubules that runs
perpendicular to sarcoplasmic reticulum
and connects it to the extracellular fluid
sarcomere
functional unit of the muscle fiber
Z-line
boundary of a sarcomere that gives
striated appearance
myofibril
fiber that runs parallel to the cell
consisting of thick (myosin) and thin
(actin) filaments
troponin, tropomyosin
two proteins that make the sarcomere
contract
nueromuscular junction
the synapse between the axon of a
motor neuron and skeletal muscle
acetylcholine
neurotransmitter for skeletal muscle
twitch
brief contraction caused by single action
potential
summation effect
larger contraction after second action
potential
tetanus
smooth, sustained contraction caused
by multiple action potentials, blending
twitches
fatigue
muscle tires out after too much
stimulation
endocrine system
organ system that secretes hormones for
organismal control
nervous system
organ system that uses neurotransmitters
for organismal control
hormone
chemical produced by endocrine system
and moves through the blood to target
that can be far from endocrine gland
(can be short-lived or long-term
response)
endocrine gland
ductless gland that secretes hormones
into blood
ecdysone
hormone that controls metamorphosis
tropic hormone
hormone that stimulates other glands to
release hormones
pheromone
chemical carrying a message between
different individuals of the same species
growth hormone
hormone produced and released by the
anterior pitiuitary to stimulate growth of
bones
luteinizing hormone
hormone produced and released by the
anterior pitiuitary to stimulate ovaries
and testes
thyroid-stimulating
hormone produced and released by the
hormone
anterior pitiuitary to stimulate thyroid
adrenocorticotropic
hormone produced and released by the
hormone
anterior pitiuitary to stimulate adrenal
cortex
follicle-stimulating
hormone produced and released by the
hormone
anterior pitiuitary to stimulate gonads to
produce sperm and ova
prolactin
hormone produced and released by the
anterior pitiuitary to stimulate mammary
glands to produce milk
oxytocin
hormone produced by the
hypothalamus and stored/released by
the posterior pituitary to stimulate
contractions of uterus and to stimulate
mammary glands to produce milk
thyroxin (T3 and T4)
hormone produced and released by the
thyroid to control metabolic rate
calcitonin
hormone produced and released by the
thyroid to lower blood calcium levels by
building bone
parathormone
hormone produced and released by the
parathyroid to raise blood calcium levels
by dissolving bone
glucocortoid
class of hormones produced and
released by the adrenal cortex to raise
blood sugar levels through
gluconeogenesis
mineralocorticoid
class of hormones produced and
released by the adrenal cortex to
regulate osmotic potential
epinephrine,
two hormones produced and released
norepinephrine
by the adrenal medulla to initiate the
"fight or flight" response
insulin
hormone produced and released by the
beta cells of the islets of Langerhans in
the pancreas to lower blood glucose
levels by absorbing blood glucose
glucagon
hormone produced and released by the
alpha cells of the islets of Langerhans in
the pancreas to raise blood glucose
levels by breaking down glycogen in
liver
thymosin
hormone produced and released by the
thymus to stimulate T lymphocytes
melatonin
hormone produced and released by the
pineal for biorhythms
estrogen
hormone produced and released by the
ovaries to stimulate uterine lining,
promote development and maintenance
of primary and secondary characteristics
of females
progesterone
hormone produced and released by the
ovaries to promote uterine lining growth
androgen
class of hormones produced and
released by the testes to support sperm
production and promote secondary sex
characteristics
hypothalamus
bridge between the endocrine and
nervous system
gonadotropic-releasing
hormone secreted by neurosecretory
hormone
cells of hypothalamus to stimulate
anterior pituitary to secrete FSH and LH
prolactin-releasing
hormone released by the hypothalamus
hormone
to stimulate anterior pituitary to secrete
prolactin
feedback mechanism
self-regulating mechanism that increases
or decreases the level of a particular
substance
positive feedback
feedback that enhances an already
existing response to bring an event to an
end
negative feedback
fedback to maintain homeostasis by
keeping levels of chemicals constant
thyrotropin-releasing
hormone released by the hypothalamus
hormone
to stimulate the anterior pituitary to
secrete thyroid-stimulating hormone
steroid hormone
hormone made from steroids that
diffuse into cell and bind to intracellular
receptor
peptide hormone
hormone made from protein that binds
to extracellular receptor and triggers
secondary messenger
testosterone
primary androgen secreted by the testes
and binds to cells with testosterone
receptor
androgen insensitivity
syndrome in which XY males lack
syndrome
testosterone receptors so lack many
sexual characteristics
glycogen
enzyme that converts glycogen into
phosphorylase
glucose
kinase cascade
signal transduction pathway using kinase
enzymes
central nervous system
part of nervous system consisting of
brain and spinal cord
peripheral nervous
system
sensory nervous system
part of nervous system consisting of all
nerves outside CNS
part of PNS that conveys information
from sensory receptors or nerve endings
motor nervous system
part of PNS that controls actions
somatic nervous system
part of motor nervous system that
controls voluntary muscles,
acetylcholine
autonomic nervous
part of motor nervous system that
system
controls involuntary muscles
sympathetic nervous
part of ANS that causes the fight or
system
flight response, norepinephrine
parasympathetic
part of ANS that causes the rest and
nervous system
digest response, acetylcholine
neuron
nerve cell
dendrite
sensory processes of a neuron that
receives incoming messages from other
cells
axon
long process of a neuron that transmits
impulse to another cell
myelin sheath
fatty layer wrapped around axon
Schwann cells
cells that form the myelin sheath of
axons
sensory neuron
neuron that receives initial stimulus from
sensory organ
motor neuron
neuron that stimulates muscles or glands
effector
muscle or gland that carries out neuron
impulse
interneuron (association
neuron that receives sensory information
neuron)
and relays it to the brain or to motor
neurons
reflex arc
inborn, automatic, and protective
response to sudden stimuli
knee-jerk reflex
simple reflex consisting of only two
neurons (sensory + motor) when hammer
strikes kneecap
withdrawal reflex
complex reflex consisting of three
neurons e.g. when touch something hot
spinal cord
a long cord down the back that
connects most nerves with the CNS
membrane potential
difference in electrical charge between
negatively charged cytoplasm and
positively charged extracellular fluid
(~-70 mV)
polarized state (resting
neuron at membrane potential of about
potential)
-70 mV
potassium leak
channels that allow potassium to diffuse
channels
outside the neuron
resting threshold
boundary where action potentials can
fire
gated-ion channel
channel that opens or closes in response
to stimuli
sodium ion-gated
channel that allows sodium to enter
channel
neuron when -50 mV
potassium ion-gated
channel that allows potassium to leave
channel
neuron when +30 mV
hypopolarize
easier for the neuron to fire
hyperpolarize
harder for the neuron to fire
action potential
impulse that travels down the axon;
reversal of membrane polarity
wave of depolarization
rapid movement of ions causing
positively-charged cytoplasm
refractory period
brief period of repolarization during
which neuron cannot respond to
another stimulus
saltatory conduction
impulse leaps from nodes of Ranvier
frequency (neuron)
determines the strength of impulse
terminal branch
end of the axon
presynaptic neuron
neuron that is transmitting the impulse
across synpase
postsynaptic neuron
neuron that is receiving the impulse
across synapse
vesicle
a membrane bound sac that contains
materials involved in transport of the cell
neurotransmitter
chemical used by a neuron to transmit
an impulse across a synapse to another
cell
calcium-gated channel
channel that allows calcium into the
terminal branch when depolarized due
to action potential
esterase
enzyme that destroys neurotransmitter
serotonin
a neurotransmitter; associated with
improved mood and other positive
emotions
dopamine
a neurotransmitter that regulates motor
behavior, motivation, pleasure, and
emotional arousal
norepinephrine
the primary neurotransmitter for
sympathetic system
cerebrum
largest section of the brain that deals
with learning, emotion, etc.; divided into
left and right hemispheres
cerebullum
section of the brain dealing with
coordination, movement, and balance
brainstem
section of the brain dealing with
homeostatic functions and relaying
sensory information
cone
modified neuron; photoreceptor in the
retina that distinguishes different colors;
embedded with visual pigment
cornea
tough, clear covering that protects the
eye and allows light to pass through
humor
fluid that maintains the shape of the
eyeball
iris
colored part of the eye that controls the
size of the pupil and how much light
enters the eye
lens
focuses light on the retina
opsin
a membrane protein bound to a lightabsorbing pigment molecule
pupil
small opening in the middle of the iris
where light enters the eye
reetina
on the back of the eyeball; converts
light to nerve impulses that are carried
to the brain; consists of 5 layers of
neurons
retinal
light-absorbing pigment in rods and
cones
rhodopsin
a visual pigment consisting of retinal and
opsin; upon absorbing light, retinal
changes shape and separates from
opsin
rods
modified neurons; photoreceptors in the
retina that are extremely sensitive but
distinguish only black and white,
embedded with the visual pigment
retinal
nonspecific defense
physical or chemical barrier that
prevents pathogens from entering the
body; not specific to particular
pathogen
lysozyme
antimicrobial enzyme involved in
nonspecific defense
histamine
triggers vasodilation, secreted by
basophils and mast cells, responsible for
cold symptoms
phagocyte
leukocyte that ingests invading fungal
and bacterial microbes
basophil
circulating leukocyte that secretes
histamine
mast cell
cell found in connective tissue that
secretes histamine
vasodilation
enlargement of blood vessels
vasoconstriction
making blood vessels smaller
prostaglandin
a lipid released by damaged tissue cells
that intensifies the effects of histamine
(i.e. vasodilation)
cytokine
signaling molecule released by
neutrophils and macrophages to
promote blood flow
fever
activated macrophages raise body's
temperature to increase metabolic
activity and kill off invaders faster
neutrophil
phagocyte that engulfs microbes and
quickly die
macrophage
engulf huge numbers of microbes over a
long period of time and digest using
lysozyme, superoxide anion, and nitric
oxide
chemotaxis
process by which phagocytes migrate to
infected site in response to chemicals
monocyte
precursor cell to macrophage
pseudopod
a temporary, foot-like extension of a cell,
used for locomotion or engulfing food
complement
group of proteins that leads to the lysis
of invading cells
interferon
proteins that block against cell-to-cell
viral infections
natural killer cell
cell that attacks virus-infected or
cancerous cells and cause it to lyse
adaptive defense
defense against a particular pathogen
antigen
marker for a cell, esp. pathogens
recognition
antigen receptors on B and T
lymphocytes bind to specific antigens
on antigen-presenting cells
epitope
accessible piece of antigen that elicits
an immune response from B or T cell
activation
antigen receptors of B and T cells cause
proliferation into effector and memory
cells
effector phase
phase in which B cells produce humoral
response and T cells a cell-mediated
response
T lymphocyte
lymphocytes that mature in the thymus
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