Evaluator: _____________________ 3D Model Medicinal Chemistry Evaluatee: _____________________ Student Presentation Version Creativity Accuracy Engineering Design Overall Model Developing The model has few creative aspects, is not personalized and has little of no unique details. Proficient The model has some creative aspects and personalization’s, and has a few unique details. Exemplary The model is clearly creative and personalized and includes details unique to the features of the model. The model correctly depicts multiple aspects of their drugs desired effect in the human body. The student generates a The model accurately model but it does not depicts one aspect of the accurately depict an drugs desired effect in aspect of the drugs the human body. desired effect in the human body. The model does not The model illustrates The model clearly illustrate that the student that the student had a illustrates a high level of has a design plan, and plan in place for the diligence that is a the model as a result is model and integrated the product of correct sloppy, unkempt, and research on the drugs planning, integrated the the materials used are mechanism action into research on the drugs superficial. Research is the model. mechanism action and not integrated into the illustrates model. thoughtfulness. The model does not The model follows most The model follows all follow the outlined parameters, is turned in parameters, is turned in parameters, is not turned on time and looks like a on time, and is clearly a in on time, and does not science model. medicinal chemistry look like a scientific model. model. You are required to see four presentations and evaluate their model based off the criteria above. Additionally, you will write down your peers’ responses to any 3 questions below. 1. What drug do you have? List both the common name and the chemical name. 2. What class of drugs does this belong to? 3. Who/what company discovered the drug? When did they discover it? (How old is the drug?) 4. What disease or symptom does the drug help mediate? 5. What are the biological and physical manifestations of the disease/symptom? (I.E. Depression is characterized by a variety of neurological interactions, many of which affect the neurotransmitters serotonin and norepinephrine, which can cause mood, sleep, behavioral and cognitive symptoms.) Be as detailed as possible! 6. Do you need a prescription for the drug or is it over the counter? 7. What is the mechanism for the drugs action? How does it work your body? Is it in pill form or does it require injection? What receptors/ion channels/enzymes does it bind to? BE AS SPECIFIC AS POSSIBLE! 8. What are the side effects of the drug? Are there any severe drug interactions to worry about? Is it possible to overdose on this drug? 9. What aspect of the drug do you propose to model? Briefly describe your idea for the model. (You can include pictures if you want.)