Hypertrophy
Definition
Increase in the size of the
parenchymal cells resulting in
enlargement of the organ or
tissue, without any changes in the
number of cells.
Occurs due to,
Increased
demand
By hormonal stimulation
Two types,
Physiologic hypertrophy
Hormonal – Uterus in pregnancy
Increased demand – Skeletal muscles
Pathologic hypertrophy
Increased demand – heart muscle in hypertension
Pathological hypertrophy
Hypertrophy of cardiac muscle
Hypertrophy of Smooth muscle
Hypertrophy of skeletal muscles
Compensatory hypertrophy in any organ