BURNS BURNS ■ tissue damage and cell death caused by intense heat, electricity, UV radiation (sunburn), or certain chemicals (such as acids), which denature proteins and cause cell death in the affected areas. TWO LIFE-THREATENING PROBLEMS: 1. The body loses its precious supply of fluids • Dehydration and electrolyte imbalance follow 2.Infection RULE OF NINES ■ 11 areas (each accounting for 9% of the total body surface area, plus an additional area surrounding the genitals (the perineum) representing 1 percent of body surface area) CLASSIFICATION OF BURNS according to their severity 1. First-degree (superficial) 2. Second-degree (superficial partialthickness burns) 3. Third-degree (full-thickness burns) 4. Fourth-degree (full-thickness burns with deep-tissue involvement) FIRST-DEGREE BURNS ■ only the superficial epidermis is damaged ■ red and swollen ■ generally heal in 2-3 days ■ Example: Sunburn without blistering SECOND-DEGREE BURNS ■ the epidermis and the superficial part of the dermis is damaged ■ red, painful, and blistered ■ regeneration can occur THIRD-DEGREE BURNS ■ both the epidermis and the dermis is damaged and often extend into the subcutaneous tissue ■ blistered, blanched, or blackened ■ not painful ■ regeneration is not possible FOURTH-DEGREE BURNS ■ full-thickness burns, but they extend into deeper tissues ■ dry and leathery ■ require surgery and grafting ■ in severe cases, amputation may be required In general, burns are considered critical if any of the following conditions exists: ■ Over 30 percent of the body has second-degree burns. ■ Over 10 percent of the body has third- or fourth-degree burns. ■ There are third- or fourth-degree burns of the face, hands, feet, or genitals. ■ Burns affect the airway. ■ Circumferential (around the body or limb) burns have occurred. – Facial burns are particularly dangerous because of the possibility of burns in respiratory passageways, which can swell and cause suffocation. – Circumferential burns can restrict movement, and depending on location, can interfere with normal breathing. TISSUE REPAIR Wound Healing 1. Inflammation sets the stage. ■ Injured tissue cells and others release inflammatory chemicals that make the capillaries very permeable. A fluid rich in clotting proteins construct a clot to stop blood loss and hold the edges of the wound together. When the clot is exposed to air, it quickly dries and hardens and forms a scab. 2. Granulation tissue forms. ■ A delicate pink tissue (granulation tissue) composed of largely new capillaries, forms on the surface of the wound when wound is healing. It gets its red color from the new blood vessels that are forming to deliver nutrients to the tissue. This tissue contains phagocytes, which eventually dispose of the blood clot, and connective tissue. 3. Regeneration and fibrosis. ■ The surface epithelium begins to regenerate and makes its way between the granulation tissue and the scab. Its final result covers an underlying area of fibrosis (scar), and the scar is either seen invisible or visible as a thin white line which depends on the severity of the wound.