BLADDER CANCER What is it? Bladder cancer occurs in the tissues of the bladder. There are three types of bladder cancer: Transitional cell carcinoma- is the most common type of bladder cancer. It begins in the transitional cells in the inner layer of the bladder. Squamous cell carcinoma- is a rare cancer in the United States which forms in the bladder after a long-term infection or irritation in the bladder. Adenocarcinoma- is a rare cancer in the United States which forms in the bladder after a longterm bladder irritation and inflammation. What causes it? Smoking and other tobacco use Exposure to chemicals, especially working in a job that requires exposure to chemicals Past radiation exposure Chronic irritation of the lining of the bladder Parasitic infections, especially in people who are from or have traveled to certain areas outside the United States How is it diagnosed? a urinalysis an internal examination to feel for lumps that may indicate a cancerous growth a cystoscopy, a biopsy a CT scan to view the bladder an intravenous pyelogram (IVP) X-rays How will it present? blood in the urine painful/painless urination frequent urination urgent urination urinary incontinence pain in the abdominal area pain in the lower back The tumor can actually obstruct the entrance of urine into the bladder, or the exit of urine from the bladder. This may cause severe flank (lower back) pain, infection, and damage to the kidneys. Treatment/Interventions Transurethral resection of bladder or tumor (TURBT) surgery to remove the tumor from the bladder, cystectomy (removal of bladder, partial or full) chemotherapy, radiation immunotherapy, which involves taking a medication that causes your immune system to attack the cancer cells. Stage 0 bladder cancer hasn’t spread past the lining of the bladder. Stage 1 bladder cancer has spread past the lining of the bladder, but it hasn’t reached the layer of muscle in the bladder. Stage 2 bladder cancer has spread to the layer of muscle in the bladder. Stage 3 bladder cancer has spread into the tissues that surround the bladder. Stage 4 bladder cancer has spread past the bladder to the neighboring areas of the body .