The Na/K Pump Mechanism Cut out the pictures and stick them in the correct sequence. Cytoplasmic Na+ binds to the Na/K pump. Na+ binding stimulates the phosphorylation by ATP Phosphorylation causes the protein to change its shape, expelling N a+ to the outside. Extracellular K+ binds to the protein triggering release of the phosphate group Loss of the phosphate group restores the proteins original confirmation K+ is released and Na+ sites are receptive again and the cycle repeats.