Bleeding, also known as hemorrhaging is blood escaping from the circulatory system.Bleeding can occur internally, where blood leaks from blood vessels inside the body, or externally, either through a natural opening such as the mouth, nose, ear, urethra, vagina or anus , or through a break in the skin • • Blood loss Hemorrhaging is broken down into four classes by the American College of Surgeons' advanced trauma life support(ATLS). Class I Hemorrhage involves up to 15% of blood volume. There is typically no change in vital signs and fluid resuscitation is not usually necessary. Class II Hemorrhage involves 15-30% of total blood volume. A patient is often tachycardic with a narrowing of the difference between the systolic and diastolic blood pressures. The body attempts to compensate with peripheral vasoconstriction. Skin may start to look pale and be cool to the touch. The patient may exhibit slight changes in behavior. Volume resuscitation with crystalloids (Saline solution or Lactated Ringer's solution) is all that is typically required. Blood transfusion is not typically required. • • Class III Hemorrhage involves loss of 3040% of circulating blood volume. The patient's blood pressure drops, the heart rate increases, peripheral hypoperfusion (shock), such as capillary refill worsens, and the mental status worsens. Fluid resuscitation with crystalloid and blood transfusion are usually necessary. Class IV Hemorrhage involves loss of >40% of circulating blood volume. The limit of the body's compensation is reached and aggressive resuscitation is required to prevent death. Types • Mouth • Tooth eruption – losing a tooth • Hematemesis – vomiting fresh blood • Hemoptysis – coughing up blood from the lungs Anus • Melena - upper gastrointestinal bleeding • Hematochezia – lower gastrointestinal bleeding, or brisk upper gastrointestinal bleeding Urinary tract • Hematuria – blood in the urine from urinary bleeding • • • Upper head • Intracranial hemorrhage – bleeding in the skull. • Cerebral hemorrhage – a type of intracranial hemorrhage, bleeding within the brain tissue itself. • Intracerebral hemorrhage – bleeding in the brain caused by the rupture of a blood vessel within the head. See also hemorrhagic stroke. • Subarachnoid hemorrhage (SAH) implies the presence of blood within the subarachnoid space • Lungs • Pulmonary hemorrhage • Gynecologic • Vaginal bleeding • Postpartum hemorrhage • Breakthrough bleeding • Ovarian bleeding. :polycystic ovary syndrome undergoing transvaginal oocyte retrieval. • Gastrointestinal • Upper gastrointestinal bleed • Lower gastrointestinal bleed • Occult gastrointestinal bleed Revealed and concealed hemorrhage Primary, reactionary and secondary hemorrhage Surgical vs non surgical hemorrhage In operation theatre Hb is poor indicator Degree of haemorrhage is classified in % of volume loss External vs concealed Direct external pressure Wide bore cannula History of NSAIDS, history of aneurysm Fresh bleeding,malaena Abdominal tenderness Cavitary haemorrhage is excluded by rapid investigation; abdominal u/s (FAST) focused abdominal sonar for trauma, CT scan Rapidly moved to haemorrhage control place theatre, endoscopy or angiography suites Control must be achived rapidly to prevent the pt. entering the triad of coagulopathy- acidosis- hypothermia No unnecessary investigation or procedure before bleeding control Damage control surgery Arrest of hemmorrhage Control sepsis Protect from further injury 1. 2. 3. 4. The four central strategies of DCR are: Anticipate and treat acute traumatic coagulopathy Permissive hypotension until haemorrhage control Limit crystalloid and colloid infusion to avoid dilutional coagulopathy Damage control surgery to control haemorrhage and preserve physiology. Damage control resuscitation strategies have been shown to reduce mortality and morbidity in patients with exsanguinating trauma and may be applicable in other forms of acute haemorrhage. Blood transfusion is generally the process of receiving blood or blood products into one's circulation intravenously. Transfusions are used for various medical conditions to replace lost components of the blood. Early transfusions used whole blood, but modern medical practice commonly uses only components of the blood, such as red blood cells, white blood cells, plasma, clotting factors, and platelets Whole blood Packed red cell Fresh frozen plasma(FFP); rich in coagulation factors removed from whole blood Cryoprecipitate; rich in factor Vlll and fibrinogen platelets concentrate Acute blood loss Anemia during surgery Symptomatic chronic anemia Hb >10 g% indication of blood transfusion ?? Transfusion reaction Antibodies present in recipient’s serum are incompatible with donors blood results transfusion reaction ABO incompatibility result in severe and potentially fatal hemolysis and multiple organ failure. Allergic reaction Infections Air embolism Thrombophlebitis coagulopathy hypocalcemia hyperkalaemia hypokalaemia hypothermia. <6 Probably will benefit from transfusion 6–8 Transfusion unlikely to be of benefit in the absence of bleeding or impending surgery >8 No indication for transfusion in the ◦ absence of other risk factors First-line therapy, therefore, is intravenous access and administration of intravenous fluids. Access should be through wide-bore cannula. Long, narrow lines, such as central venous catheters, have too high a resistance to allow rapid infusion and are more appropriate for monitoring than fluid replacement therapy. Debate more important to understand how and when to administer it. In most studies of shock resuscitation there is no overt difference in response or outcome between crystalloid (water soluble)solutions or colloids more crystalloid than colloid administered in blinded trials. On balance, there is little evidence to support the administration of colloids, which are more expensive and have worse side-effect profiles. If blood is being lost, the ideal replacement fluid is blood, although crystalloid therapy may be required while awaiting blood products. THANK YOU