Summarize the principle of the basic techniques of tissue preparation. Explain the principle of staining with haematoxylin and eosin (H & E). Explain electron dense and electron lucent terms. Topics MICROTECHNIQUES & MICROSCOPY ILOs of the Course Weight % Hours MASTER BLUEPRINT OF THE FIRST YEAR HISTOLOGY DEPARTMENT Bloom's Taxonomy know. compr. app. analy sis Marking syn. eval. Method of Assessment 5% 20% 5% 40% 30% Total Marks √ 3 (4%) √ √ MCQ √ √ MCQ 0.25 0.25 7 Describe and correlate the molecular structure of the cell (plasma) membrane to its microscopic structure. Describe and correlate the microscopic structure “LM and EM” and function of mitochondria. 12 (16%) CELL CYTOPLASM List the components of the cell. √ 2.25 6 √ √ √ √ √ √ 1 √ MCQ Short essay Short answer √ MCQ Short essay Short answer OSPE 15.25 Describe and correlate the microscopic structure “LM and EM” and function of the ribosome and RER. Describe and correlate the microscopic structure “LM and EM” and function of the SER and Golgi Describe and correlate the microscopic structure “LM and EM” and function of the lysosome, peroxisome and proteasome Describe and correlate the microscopic structure “LM and EM” and function of the microtubules, centriole, cilia and flagella Describe and correlate the microscopic structure “LM and EM” and function of the cytoplasmic filaments and cytoplasmic inclusions √ √ √ √ √ √ √ MCQ Short essay Short answer OSPE √ √ √ √ MCQ Short essay Short answer √ MCQ Short essay Short answer OSPE √ MCQ Short essay Short answer OSPE √ MCQ Short essay Short answer √ √ CELL NUCLEUS Describe and correlate the microscopic structure “LM and EM” and function of the nuclear envelop and chromatin √ MCQ Short essay Short answer OSPE √ √ √ √ 1 5 (6.7%) √ √ √ 2 8 0.5 9.5 Describe and correlate the microscopic structure “LM and EM” and function of the nucleolus. √ √ Define the cell cycle and describe its stages. √ √ √ VOLUNTARY MUSCLES √ √ MCQ √ √ √ √ √ MCQ √ MCQ Short essay Short answer OSPE 4 (5.3%) √ MCQ Short essay Short answer MCQ Short essay Short answer √ 0.5 2 0.5 10 6 √ 3 √ √ √ √ √ 3 MCQ Short answer √ 1 7 (9.3%) CONNECTIVE TISSUE Define stem cells and list their characters. List and explain some types of chromosomal abnormalities. Describe the microscopic structure and correlated function of the skeletal muscle fibers Know growth and regeneration of the skeletal, muscles. Describe the general structure of the connective tissue. Describe the structure of extra-cellular matrix. Describe the structure, staining properties and the correlated functions of the collagen, elastic and reticular fibers. Describe the structure, staining properties and correlated functions of the different types of the connective tissue cells. √ √ √ 3 √ MCQ Short essay Short answer OSPE √ MCQ Short essay Short answer OSPE Describe the structure and functions of the different types of the connective tissue proper. List components of cartilage. Mention the types of ossification of bone. MCQ OSPE √ √ √ √ MCQ Short essay Short answer OSPE √ √ √ √ MCQ Short essay Short answer √ CARTILAGE Describe the structure and correlated function of cartilage cells. 3(4%) √ √ 7 (9.3%) BONE Correlate the molecular structure of cartilage matrix to its staining affinity. Describe the structure, correlated functions and sites of the hyaline cartilage. Describe the structure, correlated functions and sites of the elastic cartilage and the white fibro-cartilage. List the components of bone. Describe the structure and correlated functions of the bone cells and the bone matrix. Describe the structure, functions and sites of the compact and the cancellous bone. √ √ √ MCQ Short essay Short answer OSPE √ MCQ Short essay Short answer OSPE 4.5 2 1.5 1 3.5 √ 5 11.5 √ √ √ √ √ √ MCQ Short essay Short answer OSPE MCQ OSPE √ 4 3 Enumerate the different zones of the growing end of a long bone. Correlate the defective bone structure in various diseases to the hormonal and nutritional state of the body. List component of blood. √ √ √ √ √ MCQ Short essay Short answer √ MCQ Short essay Short answer OSPE √ √ √ MCQ Short essay Short answer OSPE √ √ 7 (9.3%) √ Describe the structure and functions of the bone marrow. Define haematopoiesis and list its general steps. √ √ √ 12.5 7 2.5 2 1 MCQ Short essay Short answer OSPE √ OSPE √ MCQ √ MCQ Short essay Short answer OSPE 1 INVOLUNTA RY MUSCLES Describe the microscopic structure and correlated function of the cardiac muscle fibers. √ 2 BLOOD Describe structure and correlated functions of the blood platelets √ √ Describe the microscopic structure and correlated function of RBCs. Classify leucocytes and describe the structure and correlated functions of each type of the blood leucocytes. OSPE 4(5.3%) √ √ √ 5 4.5 1.5 Describe the structure and correlated function of the moderator band. Describe the structure and correlated of the smooth muscle fibers. 5(6.7%) √ MCQ Short answer OSPE √ √ MCQ Short essay Short answer √ √ √ √ MCQ Short essay √ √ MCQ Short essay Short answer OSPE √ MCQ Short essay Short answer OSPE √ √ √ √ Short essay √ √ 1.5 0.5 4(5.3%) √ 4 2 √ √ √ √ 6 MCQ Short essay Short answer OSPE 6 4 2 BLOOD VASCULAR SYSTEM Classify epithelium and describe the structure, correlated functions and sites of each type of epithelial tissue. List the specializations of epithelial cell surfaces and describe the structure and correlated functions of each specializations. Describe the structure and correlated functions of the basement membrane and the basal lamina. Describe the general structure of the wall of a blood vessel. Describe the structure and correlated functions of the large and medium sized arteries and veins. EPITHELIUM Compare between the structure, growth and regeneration of the skeletal, the cardiac and smooth muscles. √ Describe the structure and correlated functions of the thymus. Describe the structure and correlated functions of the lymph node LYMPHOID SYSTEM Classify types of arteriovenous connections and list their correlated functions. Describe the structure and correlated functions of the antigen presenting cells. Describe the structure, site and correlated functions of the lymphoid nodules. Describe the structure of the palatine tonsil, the pharyngeal tonsil and the lingual tonsil √ √ √ MCQ Short essay Short answer √ √ MCQ Short essay Short answer √ √ MCQ Short essay OSPE 8(10.7%) Describe the structure and correlated functions of the spleen. √ √ √ √ √ √ √ √ MCQ Short essay Short answer OSPE MCQ Short essay Short answer OSPE MCQ Short essay Short answer OSPE 11 1 6 4 3 RESPIRATORY SYSTEM List the components of the conducting and respiratory portions of the respiratory system. Describe the structure and functions of the olfactory epithelium. Describe the structure and correlated functions of the larynx, trachea, bronchi, and bronchiole. √ MCQ Short essay Short answer OSPE 6(8%) √ √ √ 5 √ MCQ Short essay Short answer √ MCQ Short essay Short answer OSPE 7 8 Describe the structure and correlated functions of the respiratory bronchiole, alveolar ducts, sacs and alveoli. √ Total 100% 100% √ √ √ 73% 45% 45% MIDTERM I EXAM MIDYEAR EXAM MIDTERM II EXAM FINAL EXAM PRACTICAL, RESEARCH AND ASSIGNMENTS NOT INCLUDED MCQ: MULTIPLE CHOICE QUESTIONS SHORT ANSWER: GIVE REASON, COMPLETE SHORT ESSAY: DESCRIBE, CORRELATE, COMPARE OSPE: OBJECTIVE STRUCTURED PRACTICAL EXAM HEAD OF HISTOLOGY DEPARTMENT: PROF. DR. GHADA FAROUK MOHAMED 8 MCQ Short essay Short answer OSPE 5 20 5 40 30 100