Mutation Webquest (2016) NAME: DATE: Link #1 - http://learn.genetics.utah.edu/content/variation/mutation/ (http://learn.genetics.utah.edu/content/basics/oldtour/ <-old link) 1. A mutation is made once in every ________________ nucleotides copied. 2. Roughly, how many mutations occur every time one of our cells divide? _________________ 3. What is a mutation? _______________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ 4. All mutations are bad. This statement is true or false? EXPLAIN YOUR ANSWER __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ 5. Explain how alleles and mutation are linked. __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ 6. Why is genetic variation useful? __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ 7. What is lactase persistence, and how is it related to mutation? __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ Link #2 - http://evolution.berkeley.edu/evolibrary/article/mutations_01 Read through the article and answer the questions below. 8. For each of the type of mutation listed below, explain what happens as a result of the mutation. Substitution: __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ Insertion: __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ Deletion: __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ Frameshift: __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ 9. Describe two causes of mutation in the space below: __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ 10. Why do germline mutation have a greater impact on a species than a somatic mutation? __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ 11. How can a tiny mutation have a large impact on the new organism? __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ 12. What are How genes? __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ 13. Why would a mutation to a Hox gene have a large impact on the organism? __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ 14. Read the case study about Sickle Cell Anemia. (In a new tab, us the animation at this link to help with this https://www.dnalc.org/resources/3d/17-sickle-cell.html) a. How does sickle cell anemia effect an organism? __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ 15. How did we determine that mutations are random? __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ 16. Explain the Lederberg Experiment. __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ [NEXT PAGE] Use the Link to fill in the chart: http://learn.genetics.utah.edu/content/basics/outcomes/ Trait Shar Pei Dogs DoubleMuscled Cattle Extra-toed cats Curly Hair Disease Resistance/ Cystic Fibrosis Red Hair Song Learning in Birds Description How the DNA was changed and the result of that change Other examples 18. Using the following websites, find an article about mutation, summarize the article, explain how it relates to what we are doing currently in the class. Website used (circle) – www.sciencedaily.com www.scientificamerican.org www.sciencenews.org www.popsci.com Title of Article: ______________________________________ Author(s): ____________________________________________ Date Published: ___________________ Summary: (10 sentence minimum) __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ Explanation of how this article relates to what we are currently doing in class. (1 paragraph minimum) __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________ __________________________________________________________________________________________________
