EPIDEMIOLOGICAL ENVIRONMENT Endemic - is a disease that is always present in a certain population or region. Ex: Malaria, Chicken pox Epidemic - outbreak of a disease. Ex: Dengue, SARS Pandemic - are worldwide epidemics. An epidemic (a sudden outbreak) that becomes very widespread and affects a whole region, a continent, or the world due to a susceptible population. Ex: AIDS Factors that Cause disease: Heredity, Age, Nutritional condition, Personal hygiene , Habits Classes of diseases: 1. 2. Infectious diseases - the most important class of diseases caused by bacteria, protozoa, worms, fungi and viruses Pollution diseases – air-related pollution disease Ex: a. Emphysema COPD (chronic obstructive pulmonary disease) involves gradual damage of lung tissue, specifically thinning and destruction of the alveoli or air sacs accompanied by chronic bronchitis, with almost-daily or daily cough and phlegm. difficult to breathe Cigarette smoking not curable b. Pneumonia respiratory infection is a common lung infection caused by germs, such as bacteria, viruses, and fungi complication of the flu Pneumonia and its symptoms can vary from mild to severe life-threatening can be prevented—by getting an annual flu shot can be spread by coughing, sneezing or even breathing cough, fever, chills and shortness of breath c. Bronchitis is a condition in which the airways that move air to and from your lungs, also called bronchial tubes, become inflamed cough with mucus production shortness of breath chest discomfort and fatigue wheezing chronic bronchitis N/C Cigarette smoking is the major cause exposure to air pollution as well as dust or toxic gases productive cough (producing mucus) that lasts at least three months and happens multiple times over the course of at least two years. Acute bronchitis is a form of lower respiratory tract inflammation affecting the air tubes (bronchi) of the lungs caused by a respiratory virus and occasionally by bacterial infection Coughing up mucus that may be yellow or green A physical examination, and possibly an X-ray if you've had fever Resting and getting plenty of fluids 3. d. Lung cancer A cough that doesn't go away and gets worse over time Hoarseness Constant chest pain Shortness of breath or wheezing Frequent lung infections such as bronchitis or pneumonia Coughing up blood, Weight loss, Loss of appetite Headaches, Bone pain or fractures, Blood clots Your medical history, Your symptoms Findings from your physical exam e. Liver cancer is cancer that begins in the cells of your liver. Losing weight without trying Loss of appetite Upper abdominal pain Nausea and vomiting General weakness and fatigue Abdominal swelling Yellow discoloration of your skin and the whites of your eyes (jaundice) White, chalky stools Chronic infection with HBV or HCV Cirrhosis Nonalcoholic fatty liver disease Excessive alcohol consumption Certain inherited liver diseases Stress diseases – related to social environment of man Ex: Food poisoning foodborne illness caused by eating contaminated food. Infectious organisms — including bacteria, viruses and parasites nausea vomiting diarrhea Abdominal pain and cramps Fever Neurological symptoms such as blurry vision, muscle weakness and tingling in the arms a. Red tide is a common name for a phenomenon known as an algal bloom, an event in which estuarine, marine, or fresh water algae accumulate rapidly in the water column, or "bloom" dinoflagellate - algae, phytoplankton, are microscopic, single-celled protists, plant-like organisms fish and shellfish become poisonous for human consumption due gastrointestinal issues diarrhea nausea abdominal distress loss of motor control ataxia paresthesia vertigo muscle pain Hepatitis A is a highly contagious liver infection caused by the hepatitis A virus. usually get it when you eat or drink something that’s been exposed to poop from someone who has the virus. Jaundice (yellow eyes and skin, dark urine) Pain in your belly Clay-colored bowel movements Low-grade fever Loss of appetite Nausea Diarrhea Fatigue Eat fruits, vegetables, or other foods that were contaminated during handling Eat raw shellfish harvested from water that's got the virus in it Swallow contaminated ice Live with or have sex with someone who's infected Men who have sex with men People who inject illegal drugs b. Hepatitis B is an infection of your liver. Having chronic hepatitis B increases your risk of developing liver failure, liver cancer or cirrhosis — a condition that permanently scars of the liver. It can cause scarring of the organ, liver failure, and cancer. It’s spread when people come in contact with the blood, open sores, or body fluids of someone who has the hepatitis B virus. Jaundice. (Your skin or the whites of the eyes turn yellow, and your pee turns brown or orange.) Light-colored poop Fever Fatigue that persists for weeks or months Stomach trouble like loss of appetite, nausea, and vomiting Belly pain unprotected sex needles and syringes contaminated with infected blood. Pregnant women with hepatitis B can pass it to their babies during childbirth. c. Hepatitis C Bleeding easily Bruising easily Fatigue Poor appetite Yellow discoloration of the skin and eyes (jaundice) Dark-colored urine Itchy skin Fluid buildup in your abdomen (ascites) Swelling in your legs Weight loss Confusion, drowsiness and slurred speech (hepatic encephalopathy) Spider-like blood vessels on your skin (spider angiomas) d. Hepatitis D hepatitis delta HDV is the most severe form of hepatitis. it can lead to liver cancer or liver failure. Super-infection: You can get sick with hepatitis B first, then later come down with HDV. This is the most common way to get hepatitis D. Inject drugs Have a sex partner who has HDV Yellow skin and eyes (jaundice) Stomach upset Pain in your belly Throwing up Fatigue Not feeling hungry Joint pain Dark urine Light-colored stool From another source: a. b. c. d. e. f. g. 4. Obesity heart disease Alzheimer's disease Diabetes Depression gastrointestinal problems and asthma Allergies a. Superficial mycosis superficial fungal infections dermatophytosis or ringworm tinea versicolor antifungal drugs such as clotrimazole (Canestan) or terbinafine (Lamisil) b. c. Deep mycosis – deep fungal infection Dandruff is a common skin condition that causes white or grey flakes of skin to appear on the scalp and in the hair. 5. Developmental anomalies can be caused by environmental contaminants and unhealthy practice a. STD b. AIDS Categories of Infectious Diseases: 1. Two-factor complex – involves a pathogen (a bacterium, virus, or other microorganism that can cause disease) and man. a. Influenza is a viral infection that attacks your respiratory system — your nose, throat and lungs. Flu Common signs and symptoms of the flu include: Fever over 100.4 F (38 C) Aching muscles Chills and sweats Headache Dry, persistent cough Fatigue and weakness Nasal congestion Sore throat People at higher risk of developing flu complications include: o Young children under age 5, and especially those under 2 years o Adults older than age 65 o Residents of nursing homes and other long-term care facilities o o o o 2. Pregnant women and women up to two weeks postpartum People with weakened immune systems People who have chronic illnesses, such as asthma, heart disease, kidney disease, liver disease and diabetes People who are very obese, with a body mass index (BMI) of 40 or higher b. Acute Coryza The common cold is a viral infectious disease that infects the upper respiratory system. It is the most common infectious disease in humans and is mainly caused by coronaviruses or rhinoviruses. Pneumonia Three-factor complex- involves a pathogen, vector (vector is any agent who carries and transmits an infectious pathogen into another living organism, ex; parasite and microbe), and a man. o Malaria It’s typically transmitted through the bite of an infected Anopheles mosquito Infected mosquitoes carry the Plasmodium parasite mature parasites enter the bloodstream and begin to infect red blood cells typically found in tropical and subtropical climates Common symptoms of malaria include: shaking chills that can range from moderate to severe high fever profuse sweating headache nausea vomiting abdominal pain diarrhea anemia muscle pain convulsions coma bloody stools Malaria can cause a number of lifethreatening complications. The following may occur: swelling of the blood vessels of the brain, or cerebral malaria an accumulation of fluid in the lungs that causes breathing problems, or pulmonary edema organ failure of the kidneys, liver, or spleen anemia due to the destruction of red blood cells low blood sugar o H-fever infectious diseases that can cause severe, life-threatening illness They can damage the walls of tiny blood vessels, making them leaky. They can also interfere with the blood's ability to clot. These diseases most commonly occur in tropical areas of the world. Ex: Dengue Symptoms: 3. High fever Fatigue Dizziness Muscle, bone or joint aches Weakness Septic shock Nervous system malfunctions Coma Delirium Kidney failure Respiratory failure Liver failure o Yellow fever is a viral infection spread by a particular type of mosquito most common in areas of Africa and South America Once the infection enters the acute phase, you may experience signs and symptoms including: Fever Headache Muscle aches, particularly in your back and knees Sensitivity to light Nausea, vomiting or both Loss of appetite Dizziness Red eyes, face or tongue Toxic phase Yellowing of your skin and the whites of your eyes (jaundice) Abdominal pain and vomiting, sometimes of blood Decreased urination Bleeding from your nose, mouth and eyes Slow heart rate (bradycardia) Liver and kidney failure Brain dysfunction, including delirium, seizures and coma Four-factor complex – involves an intermediate host, vector, bacteria and man. o Plague is a serious bacterial infection that's transmitted primarily by fleas. Black Death Yersinia pestis, lives in small rodents found most commonly in rural and semirural areas of Africa, Asia and the United States. The organism is transmitted to humans who are bitten by fleas that have fed on infected rodents or by humans handling infected animals. Bubonic plague It's named after the swollen lymph nodes (buboes) Situated in the groin, armpit or neck About the size of a chicken egg Tender and firm to the touch Sudden onset of fever and chills Headache Fatigue or malaise Muscle aches Septicemic plague occurs when plague bacteria multiply in your bloodstream. Fever and chills Extreme weakness Abdominal pain, diarrhea and vomiting Bleeding from your mouth, nose or rectum, or under your skin Shock Blackening and death of tissue (gangrene) in your extremities, most commonly your fingers, toes and nose Cause: The plague bacteria, Yersinia pestis, is transmitted to humans through the bites of fleas that have previously fed on infected animals, such as: o Rats o Mice o Squirrels o Rabbits o Prairie dogs o Chipmunks Death. Most people who receive prompt antibiotic treatment survive bubonic plague. Untreated plague has a high fatality rate. Gangrene. Blood clots in the tiny blood vessels of your fingers and toes can disrupt blood flow and cause that tissue to die. The portions of your fingers and toes that have died may need to be removed (amputated). Meningitis. Rarely, plague may cause inflammation of the membranes surrounding your brain and spinal cord (meningitis). o Typhus Typhus is a disease caused by rickettsia or orientiabacteria. You can get it from infected mites, fleas, or lice. Insects and other parasites spread murine and epidemic typhus when they bite you and leave bacteria-laden feces on your skin. When you scratch the itching bug bite, you can spread the infested feces into the open bite wound or other cuts on your skin’s surface. That deposits typhus bacteria into your bloodstream. You can get scrub typhus if a mite infected with the bacterium bites you, even if you don’t scratch the bite. Symptoms: with any kind of typhus, you’ll start to feel ill about 10 days to 2 weeks after the typhus bacteria get into your body. At first, you’ll feel chills, run a fever, and develop a severe headache. You may start to breathe fast and get full-body muscle aches like what you’d have with the flu. Stomach pain and vomiting are common, too. A few days later, you might notice a spotted rash on your chest and midsection, which often spreads to other parts of your body. With scrub typhus, you might see a dark scab on the area where the chigger bit you. Complications from untreated typhus can include conditions such as pneumonia, meningitis, or septic shock. Q-fever is an infection caused by the bacterium Coxiella burnetii. Q fever is usually a mild disease with flu-like symptoms. is transmitted to humans by animals, most commonly sheep, goats and cattle. When you inhale barnyard dust particles contaminated by infected animals, you may become infected. Signs and symptoms may include: o High fever, up to 105 F (41 C) o Severe headache o Fatigue o Chills o Cough o Nausea o Vomiting o Diarrhea o Sensitivity to light Complications: Endocarditis. An inflammation of the membrane inside your heart, endocarditis can severely damage your heart valves. Endocarditis is the most deadly of Q fever's complications. Lung issues. Some people who have Q fever develop pneumonia. This can lead to acute respiratory distress, a medical emergency in which you're not getting enough oxygen. Pregnancy problems. Chronic Q fever increases the risk of miscarriage, low birth weight, premature birth and stillbirth. Liver damage. Some people who have Q fever develop hepatitis, an inflammation of the liver that interferes with its function. Meningitis. Q fever can cause meningitis, an inflammation of the membrane surrounding your brain and spinal cord.