Author: Jocelyn Svengsouk Unit: Evolution Topic: Enzymes (Day 2) NYS Standard/Performance Indicators Addressed: 5.1f Biochemical processes, both breakdown and synthesis, are made possible by a large set of biological catalysts called enzymes. Enzymes can affect the rates of chemical change. The rate at which enzymes work can be influenced by internal environmental factors such as pH and temperature. 5.1g Enzymes and other molecules, such as hormones, receptor molecules, and antibodies, have specific shapes that influence both how they function and how they interact with other molecules. Data used to inform decisions made within this lesson Regents Exams Big Idea (Unit): T How does information get passed from one generation to the next? Learning Targets – Learning objectives Content LT: I can describe what an enzyme is and why enzymes are important. Literacy LT: I can verbally outline enzyme function. Skill LT: I can create my own enzyme, name it, and show how it works on a substrate to create a product. Essential/Critical Vocabulary: enzyme, substrate, lock-and-key, shape specificity, reactant, product, catalyst, catalyze ----------------------------------------------------------------------------------------- Essential / Focus Question: How does your body carry out chemical reactions? Course: Living Environment Date: April 27, 2018 Focus of Lesson Components List only the specific standard that is emphasized in the lesson. The learning targets are created from the standards. State exactly what the student will know and be able to do as a direct result of the instruction. Include all categories (content, skill, & literacy). Start each learning target as follows: “I can…..” Consider essential vocabulary & other literacy skills embedded in the lesson. List an open-ended question that will focus the student on the unifying concept & skill of the lesson as well as promote higher-level thinking. The ability to answer the EQ should demonstrate a strong understanding of content and the ability to apply the process skills involved in making sense of new ideas. State exactly what the students will do to expose their existing knowledge, understanding, & skills required to support both the teacher and the student in connecting to the lesson. The Bridge exposes preconceptions, draws the student into the lesson, allows the opportunity for the student and teacher to build on existing knowledge and clearly see learning evolve throughout the lesson. Bridge: Regents Questions 1 Mini Lesson: Teacher will explain what an enzyme is (students will take notes on a capture sheet) and how it works by shape-specificity on a certain substrate, to make a chemical reaction happen in the body. Some examples of enzymes are amylase, DNA polymerase, catalase, pepsin, and lipase. There are pictures of these enzymes showing how the substrate fits into the enzyme, and the enzyme can either break the substrate down into parts or build something up out of parts. Enzymes usually (but not always) end in – ase. Enzymes catalyze reactions, meaning that they speed them up. Without enzymes, we would not be able to digest our food, replicate our DNA, or do cellular respiration. The enzyme remains unchanged and can be used again to do another chemical reaction. Describe exactly what you will do to connect the Bridge, Learning, Targets, & the Essential/Focus Question to the Workshop in order to guide students to construct meaning during the lesson. This part of the lesson often requires the teacher to briefly/succinctly model how students will learn while clearly guiding them to understand what & why they are learning. Workshop: List the tasks students will carry out to construct meaning. Here, students spend the majority of the lesson involved in student-centered activity that promotes learning for understanding. At the end of the workshop, students should be prepared to summarize what they have learned and (specific process skill/event involved) that defines how they learned. Students will have access to various colors of play-dough. They will create their own enzyme, give it a name for the reaction it catalyzes (should end in –ase), and create substrate(s) that the enzyme works on (must be shape specific to the enzyme), and show what products the enzyme makes in the biochemical reaction. They must accurately verbally describe the enzyme, substrate, chemical reaction, and products that result to the teacher to get credit for the lab activity. Also, they should explain what happens to the enzyme after it catalyzes the reaction (it remains unchanged and can do another reaction by binding to another substrate material). Summary: Explain how you will guide students to pause and reflect on the learning that has occurred during the workshop. What is an enzyme, and why is it important? Closure: Regents Questions Learning Extension: (HW) None PURPOSE: Understand protein function (enzymes are proteins that catalyze chemical reactions) and how shape determines function. RETEACHING PLAN: Area of lesson being retaught/revisited from previous lessons: Protein shape is important. Why is this being readdressed? The enzyme’s shape determines what substrate it can bind to and what chemical reaction it can catalyze. New strategies applied in this lesson to reteach the skill/content: List the format in which students will answer the Essential/Focus Question shared at the beginning of the lesson. This element of the lesson is critical to supporting long term memory / retention of the knowledge and skills addressed in the lesson. Describe the activity students will complete to apply (further reject or confirm) their understanding of the knowledge and skills (in a different context) presented in the lesson. Kinesthetic—making your own enzymes with play-dough 2 3