CONSISTENCY OF NATURAL, PLANT-BASED
PRESERVATIVE INGREDIENTS VIA CONVENTIONAL
PLANT BREEDING TECHNOLOGIES
Brooke Tjaden, Kemin
May 2015
© Kemin Industries, Inc. and its group of companies 2015. All rights reserved. ®™ Trademarks of Kemin Industries, Inc., U.S.A.
Plant Science
Vertically integrated
cultivation
© Kemin Industries, Inc. and its group of companies 2015. All rights reserved. ®™ Trademarks of Kemin Industries, Inc., U.S.A.
Plants are excellent sources of “Green” Chemistry
• Harvest sunlight
• Sequester CO2
• Renewable chemistry
o
o
o
o
Complex molecules
Huge variation
Optimized via breeding
Perennial options
• Applications:
o
Human Health & Personal Care
© Kemin Industries, Inc. and its group of companies 2015. All rights reserved. ®™ Trademarks of Kemin Industries, Inc., U.S.A.
Focused on molecules…
© Kemin Industries, Inc. and its group of companies 2015. All rights reserved. ®™ Trademarks of Kemin Industries, Inc., U.S.A.
Fully Vertically Integrated Process
Advanced techniques
in conventional plant breeding (no GMOs)
Breed
Proprietary
Clonal Lines
Propagate
Grow
Extract
© Kemin Industries, Inc. and its group of companies 2015. All rights reserved. ®™ Trademarks of Kemin Industries, Inc., U.S.A.
Blend
Product
Development
Market
CLS
Kemin’s Specialty Crop Development Process
Breeding & Selection
Research Agronomy
© Kemin Industries, Inc. and its group of companies 2015. All rights reserved. ®™ Trademarks of Kemin Industries, Inc., U.S.A.
Biochemical Screening
Field Agronomy Services
Breeding and Selection
Breeding & Selection:
Summerset Field Station, IA
Plant Micro-Propagation Lab
Kemin Molecular Advancement
Center, Des Moines
Hereford Greenhouse, Texas
© Kemin Industries, Inc. and its group of companies 2015. All rights reserved. ®™ Trademarks of Kemin Industries, Inc., U.S.A.
In Field Testing
SCI Kelley Research Farm, Iowa
Spearmint Test Plot, Indiana
Hereford Greenhouse, Texas
Rosemary Field Testing, Texas
© Kemin Industries, Inc. and its group of companies 2015. All rights reserved. ®™ Trademarks of Kemin Industries, Inc., U.S.A.
BIOACTIVES FROM OREGANO
Borneol
Carvacrol
Thymol
a-pinene
 High bioactive accumulation in Oregano
 Populations screened during selection process.
© Kemin Industries, Inc. and its group of companies 2015. All rights reserved. ®™ Trademarks of Kemin Industries, Inc., U.S.A.
Caryophyllene
Monitoring Targeted Molecule for Activity
Frequency distribution of the populations for carvacrol levels
90
80
70
60
Frequency
50
40
30
20
10
0
< 0.1 0.1-0.3 0.3-0.6 0.6-0.9 0.9-1.2 1.2-1.5 1.5-1.8 1.8-2.0 2.0-2.5 2.5-3.0 3.0-3.5 3.5-4.0 4.0-4.5 >5.0
Carvacrol % on dry matter basis
Pop I
Pop II
Pop III
Pop IV
Pop V
Pop VI
Pop VIII
Pop IX
Pop XII
Pop XIII
PopXIV
PopXV
Pop VII
© Kemin Industries, Inc. and its group of companies 2015. All rights reserved. ®™ Trademarks of Kemin Industries, Inc., U.S.A.
Kemin Internal Document 10-00168
Chemotypic Differences
Greek Oregano
KI1850
KI1750
© Kemin Industries, Inc. and its group of companies 2015. All rights reserved. ®™ Trademarks of Kemin Industries, Inc., U.S.A.
Kemin Internal Document 14-00122
© Kemin Industries, Inc. and its group of companies 2015. All rights reserved. ®™ Trademarks of Kemin Industries, Inc., U.S.A.
Steam Distillation
Lab scale (1 gallon)
© Kemin Industries, Inc. and its group of companies 2015. All rights reserved. ®™ Trademarks of Kemin Industries, Inc., U.S.A.
Field test scale (35 gallon)
Planting & Growing
Propagation
Planting in Iowa
Planting in Texas
Field Establishment - Year 2
© Kemin Industries, Inc. and its group of companies 2015. All rights reserved. ®™ Trademarks of Kemin Industries, Inc., U.S.A.
Monitoring Seasonal Variation in Targeted
Bioactives
Variation of Carvacrol/Thymol in selected oregano lines
Carvacrol/thymol %
8
KIOv-1721
KIOv-1750
KIOv-1791
KIOv-1835
KIOv-1843
KIOv-1850
7
6
5
4
3
2
© Kemin Industries, Inc. and its group of companies 2015. All rights reserved. ®™ Trademarks of Kemin Industries, Inc., U.S.A.
Kemin Internal Document 14-00122
Harvesting & Steam Distillation
Harvest cut close to ground
Dried in Field
Collected in Steam Wagon
Steam Distillation
© Kemin Industries, Inc. and its group of companies 2015. All rights reserved. ®™ Trademarks of Kemin Industries, Inc., U.S.A.
Raw Material Testing
• State-of-the-art analytical testing laboratory operated
by scientists
o
Highly-technical equipment
can test for ultra-sensitive levels
of contamination at parts
per quadrillion
o
o
Analysis capabilities: dioxins,
PCBs and pesticides
Quick turn around time
allows for rapid detection
and identification of potential
contaminants (confirmatory)
© Kemin Industries, Inc. and its group of companies 2015. All rights reserved. ®™ Trademarks of Kemin Industries, Inc., U.S.A.
Focused on molecules…
© Kemin Industries, Inc. and its group of companies 2015. All rights reserved. ®™ Trademarks of Kemin Industries, Inc., U.S.A.
Natural Market Trends
Naturalness
Environment
Climate
change
Sustainability
Organic
farming
Lifestyle
Localisation
Healthier
living
Simplicity/
back to
basics
Nostalgia
Varying levels of naturalness
Mainstream naturals
Speciality naturals
Consumer is going to outsmart greenwashing at
some point but critical to making that leap:
THE PRODUCTS/INGREDIENTS HAVE
TO BE EFFICACIOUS
© Kemin Industries, Inc. and its group of companies 2015. All rights reserved. ®™ Trademarks of Kemin Industries, Inc., U.S.A.
Source: Euromonitor, Natural Ingredients: A Sustained Push for Sustainable Options, February 2014
The Need for Natural Preservatives
•
•



Cosmetic products are easily contaminated with micro-organisms
Preservatives are included in formulation to:
Prevent and protect from contamination
Extend shelf life
Ensure that products remain safe
• Use of conventional synthetic preservatives:
(paraben or phenoxyethanol)
• Negative media
• Alerted consumers pressure
+
• Natural trend
• Demand of effective, safe and
natural preservatives
NATURAL BROAD-SPECTRUM PRESERVATIVE ALTERNATIVES
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Preservative Efficacy Testing (PET) - Results
Treatments
Untreated control
0.5% Caprylic Acid (and) Origanum vulgare Leaf Extract
© Kemin Industries, Inc. and its group of companies 2015. All rights reserved. ®™ Trademarks of Kemin Industries, Inc., U.S.A.
Caprylic Acid (and) Origanum vulgare
Leaf Extract reduces:
• Bacteria by 5 logs within 2 days
• Yeast by 3 logs within 2 days
• Mold by 4 logs within 14 days
1.0% Caprylic Acid (and) Origanum vulgare Leaf Extract
1.0% Phenoxyethanol (and) Ethylhexylglycerin
Formulation pH: 5.5
* Please note that certain statements, product labelling and claims may differ by geography or as required by government requirements Source: Kemin Internal Document 14-00086
Questions?
© Kemin Industries, Inc. and its group of companies 2015. All rights reserved. ®™ Trademarks of Kemin Industries, Inc., U.S.A.