CURRICULUM VITAE Selwyn M. Vickers, M.D., F.A.C.S. PERSONAL INFORMATION: Name: Citizenship: Selwyn M. Vickers, M.D., F.A.C.S. United States of America Email: smv@uab.edu RANK/TITLE: Senior Vice President for Medicine Dean, School of Medicine James C. Lee, Jr. Endowed Chair Professor of Surgery Department: Business Address: School of Medicine Dean’s Office University of Alabama at Birmingham 1203 Faculty Office Tower 1720 2nd Avenue South Birmingham, Alabama 35294-3412 Office Phone: Office Fax: (205) 934-1111 or (205) 934-1997 (205) 975-6190 HOSPITAL AND OTHER (NON-ACADEMIC) APPOINTMENTS: Staff surgeon: Staff surgeon: Staff surgeon: Staff surgeon: Staff surgeon: University of Minnesota Physicians University of Alabama at Birmingham Hospital Birmingham Veteran’s Administration Medical Center Johns Hopkins Hospital Johns Hopkins Bayview Hospital EDUCATION: Johns Hopkins University Baltimore, MD Bachelor of Art – Natural Sciences 1982 Johns Hopkins University School of Medicine Baltimore, MD Doctor of Medicine 1986 POSTGRADUATE EDUCATION: NIH Dr. Bertram Sacktor, NIH Department of Aging Research Fellow/Gerontology Research Center Phosphate and Sodium Transport Studies of Across Kidney Brush Border Cell Membranes Summer 1982 NIH Dr. Paul Albrecht, Division of Virology, Bureau Research Fellow of Biologies of the Food and Drug Administration, Development of Hemoagglutination Inhibition Test for Parainfluenza Virus Type I and III Summer 1983 MILITARY SERVICE: None LICENSURE: 1990 1994 2006 BOARD CERTIFICATION: 1994 2003 2008 State of Maryland State of Alabama State of Minnesota D38207 18186 American Board of Surgery American Board of Surgery American Board of Surgery POSTDOCTORAL TRAINING: 1986 – 1988 Surgical Internship Johns Hopkins University 1988 – 1990 Surgical Research Fellowship Johns Hopkins University 1990 – 1991 (6 months) Registrar Surgery John Radcliffe Hospital Oxford, England 1991 – 1993 Surgical Residency Chief Residency Johns Hopkins University 1993 – 1994 Fellowship - Surgical Oncology Johns Hopkins University 1993 – 1994 Instructor in Surgery Assistant Chief of Service Johns Hopkins University Selwyn M. Vickers, M.D. Curriculum Vitae 2 revised 09.19.2013 ACADEMIC APPOINTMENTS: 2013 – Present Senior Vice President of Medicine Dean, School of Medicine James C. Lee, Jr. Chair University of Alabama at Birmingham (UAB) Birmingham, AL 2006 - 2013 Jay Phillips Professor and Chairman Department of Surgery, University of Minnesota, Minneapolis, MN 2006 - 2013 Associate Director, Translational Research Masonic Cancer Center (an NCI-CCC) Minneapolis, MN 2006 – 2013 Director, Research Training Center for Health Equity and Education Core Minneapolis, MN 2003 – 2006 Professor Department of Surgery, UAB Birmingham, AL 2003 – 2006 Senior Scientist UAB Comprehensive Cancer Center Birmingham, AL 2002 – 2006 Co-Director UAB Minority Health & Research Center, Birmingham, AL 2001 – 2006 John H. Blue Chair of General Surgery Department of Surgery, UAB Birmingham, AL 2000 – 2006 Chief, Section of GI Surgery Department of Surgery, UAB Birmingham, AL 2000 – 2006 Associate Scientist UAB Gene Therapy Center Birmingham, AL 1999 – 2003 Associate Professor Department of Surgery, UAB Birmingham, AL 1998 – 2006 Co-Director UAB Pancreaticobiliary Center Birmingham, AL 1994 – 2003 Associate Scientist UAB Comprehensive Cancer Center Birmingham, AL 1994 – 1999 Assistant Professor Department of Surgery, UAB Birmingham, AL 1993 – 1994 Instructor Department of Surgery, Johns Hopkins Hospital, Baltimore, MD Selwyn M. Vickers, M.D. Curriculum Vitae 3 revised 09.19.2013 AWARDS/HONORS: 1982 J.F. Reed Four-year Academic Medical Scholarship ($30,000) 1986 The National Medical Commonwealth Outstanding Minority Medical Student ($5,000) 1989 Recipient of Johns Hopkins Hospital Department of Surgery, George D. Zuidiema Resident Research Award 1990 Baltimore Academy of Surgery Resident Research Award 1994 – 2004 UAB Argus Society Excellence in Teaching Award 1995 – 1999 Robert Wood Johnson Research Fellow 1996 – 1997 Best Clinical Professor – Cadecus Society, University of Alabama School of Medicine 1997 Graduating Class 1996 – 1997 Presidents Award for Excellence in Teaching, University of Alabama School of Medicine 1998 – 1999 Society for Surgery of the Alimentary Tract Young Clinician Award 2000 First Faculty Member Selected as Commencement Speaker for University of Alabama School of Medicine, Graduating Class of 2000 2001 James IV Fellow - James IV Association of Surgeons, Inc. 2001 AOA – UAB School of Medicine 2002 – 2003 2005 – 2006 2011 – 2012 2012 - 2013 Best Doctors in America 2002 – 2003 Best Doctor in Annual Best Regional Doctors 2004 – 2006 Best Doctor in Birmingham Magazine Annual Best Doctors Issue 2005 – 2012 America’s Top Doctors 2006 Who’s Who in Black Birmingham 2008 America’s Leading Doctors by Black Enterprise magazine 2009 Institute of Medicine (Section 6) Selwyn M. Vickers, M.D. Curriculum Vitae 4 revised 09.19.2013 2009 University of Minnesota Distinguished Faculty 2010, 2011 America’s Top Surgeons 2012, 2013 Mpls/St.Paul Top Doctors 2013 Johns Hopkins Society of Scholars PROFESSIONAL SOCIETIES: American Association for Cancer Research American Board of Surgery American College of Surgeons American Hepato-Pancreato-Biliary Association American Medical Association American Society for Clinical Oncology American Society of Gene Therapy American Surgical Association Association for Academic Surgery Halsted Society Institute of Medicine (elected 2009; inducted 2010) International Hepato-Pancreato-Biliary Association James IV Society Mineral District Medical Society Society for Surgery of the Alimentary Tract Society of Black Academic Surgeons Society of Clinical Surgery Society of Surgical Oncology Society of University Surgeons Southeastern Surgical Congress Southern Medical Association Southern Surgical Association COMMUNITY ACTIVITIES: Sunday School Teacher – Fellowship Missionary Baptist Church (2006-Present) Golden Valley Soccer Coach – (2007-2008) LEADERSHIP AND SERVICE COUNCILS AND COMMITTEES: Local: Selwyn M. Vickers, M.D. Co-Chair Department of Medicine Head Search Committee Ophthalmology Chair Search Committee Dean of Medical School Search Committee Medical School Admission Committee Chairman of the Medical School Minority Task Force Medical School Clinical Education Committee Curriculum Vitae 5 revised 09.19.2013 Minnesota Medical Association GCRC - Scientific Review Committee Chairman of the UAB Comprehensive Cancer Center Gastrointestinal Tumor Clinical Review Committee (1999-2002) President Planning Committee & Retreat John W. Kirklin Foundation Research and Education Fellowship Award Review Committee (2003) Search Committee – Director of UAB Honors Program (2003) Charity Care Committee (2003) Equity and Diversity Strategic Planning Committee (2003) Selections/Promotions Committee, General Surgery Residency Program (2003) LCME Faculty Committee (2005) Search Committee – Chairman of Anesthesiology (2005) Department of Surgery Residency Selection Committee Department of Surgery Residents Research Day – Director Cultural Competency Curriculum Steering Committee Search Committee – Comprehensive Cancer Center Director (2005) UAB T32 Research Training Program in Surgical Oncology Executive Committee (2006) Baylor College of Medicine’s Michael E. DeBakey Department of Surgery Gastrointestinal Cancer SPORE External Advisory Committee (2006) Search Committee, Chair – Department of Pediatrics Chair (2007) Clinical Chiefs Council (2006-present) University of Minnesota Physicians Executive Committee (2007-present) Medical School Mission-Based Management Executive Committee (2007-2008) Coordinated Management Committee (Academic Medical Center Medical Resource Allocation Committee – Dean, UMP CEO, UMMC CEO, Department of Surgery Chair) (2007-present) Chairman, Clinical Chief of Surgery Council Chairman, Operating Room Committee Search Committee, Chief Executive Officer for University of Minnesota Physicians Vice Chair, University of Minnesota Physicians Board (2008-present) Search Committee, Provost and Vice President for Academic Affairs, University of Minnesota (2011) Board of Directors, Minnesota Medical Foundation (2008-present) Executive Committee, Minnesota Medical Foundation (2008-present) Chair, Finance Committee, University of Minnesota Physicians (2011- 2013) Co-Chair, Resource Committee, LCME Institutional Committee (2010-2012) National: Selwyn M. Vickers, M.D. Association of Academic Surgeons Program Committee (1997-1999) American College of Surgeons Executive Committee on Allied Health (Vice Chairman) (1999-2003) NIH Advisory Council to Office of Minority Health and Research and Executive Council (National Institute on Minority Health and Health Disparities) (1998-2005) Association of Academic Surgery Representative to AAMC (1999-2003) Society of University Surgeons Social and Governmental Affairs Committee (1999-2002) Curriculum Vitae 6 revised 09.19.2013 NIH/NCI Pancreatic Cancer Research Progress Group Research (2000-2001) Chairman, Program Committee Society of Black Academic Surgeons Executive Council to Association of Academic Surgery (1999-2003) Program Leader, American College of Surgeons Post Graduate Course, Current Treatment of Pancreatic Cancer National Medical Association Executive Committee AHPA Program Committee (2003-2005) Chairman, Selection Committee – NCMHD Endowment Director Society of University Surgeons Membership Committee (2002-2003) Program Committee Chair, Society of Black Academic Surgeons (2002-2004) President-Elect, Society of Black Academic Surgeons (2004-2005) President, Society of Black Academic Surgeons (2005-2006) Immediate Past President, Society of Black Academic Surgeons (2006-2007) Executive Committee, Society of Black Academic Surgeons (2007-2009) NIH SPORE Study Section (2004-2008) NIH SPORE Parent Planning Committee (2004-2005) Society of Clinical Surgery Membership Committee Institute of Medicine (2009-present) Treasurer, Society for Surgery of the Alimentary Tract (2010-present) Member Executive Committee, Society for Surgery of the Alimentary Tract (2010-present) Director, American Board of Surgery (2009-present) Chair, Socioeconomic Issues Committee, American Board of Surgery (2009present) Boards: Selwyn M. Vickers, M.D. Society for Surgery of the Alimentary Tract (SSAT) Board of Trustees Member (2006-present) Treasurer (2010-present) Scientific Advisory Board, Pancreatic Cancer Action Network (2006-present) American College of Surgeons Board of Governors (2006-present) Society of University Surgeons Representative Board of Governors Committee on Socioeconomic Issues, Vice Chair, (2009-2010); Chair (2010-present) University of Minnesota Physicians Board of Directors (2007-present) Northwestern College Board of Trustees (2008-2013) Member, Academic Affairs Council Johns Hopkins University Board of Trustees (2008-2014) Audit Committee Academic Affairs Committee Johns Hopkins School of Medicine Board of Trustees (2008-2014) Minnesota Medical Foundation Board of Directors (2008-2012) American Board of Surgery Directors (2009-2012) General Surgery Residency Committee Surgical Oncology Advisory Committee Curriculum Vitae 7 revised 09.19.2013 EDITORIAL BOARD MEMBERSHIPS: Editorial Board: 1. 2. 3. 4. 5. 6. Archives of Surgery Journal of Surgical Research Yearbook of Surgery The American Journal of Surgery Journal of Gastrointestinal Surgery Annals of Surgery Ad-Hoc Reviewer for: 1. 2. 3. 4. 5. Surgery Mosby Yearbook of Surgery Gastroenterology Clinical Cancer Research Cancer Research MAJOR RESEARCH INTERESTS: 1. Gene therapy as an application in the treatment of pancreatobiliary tumors. 2. The role of growth factors and receptors (FGF, EGFR) in the oncogenesis of pancreatic cancer. 3. The implications of FAS expressions and Tamoxifen in the growth and treatment of cholangiocarcinoma. 4. Assessment of clinical outcomes in the surgical treatment of pancreatobiliary tumors. 5. The role of death receptors in the treatment of pancreatic cancer. TEACHING/MENTORING EXPERIENCE: 1. 2. 3. 4. 5. 6. Lecturer – 2-year clinical pathology course – Gastrointestinal Section Argus Outstanding Surgery Clerkship instructor – for four years Preceptor/lecturer – Surgical Clerkship small groups Active lecturer & clinical instructor in UAB Department of General Surgery training program Coordinator of Hepatobiliary Teaching Conference Faculty Teaching Award – 2004-2005 in UAB Department of Surgery General Surgery Residency Program 7. Director of GI Surgery Residents Teaching Conference 8. Lecturer – Surgery Core Curriculum 9. Department of Surgery – Faculty Awarded – Teacher of the Year – 3 consecutive years at University of Alabama RESEARCH FELLOWS: 1. Lorenzo Sampson, M.D. (1995-1996) - The role of Tamoxifen in the treatment of pancreatic cancer Ross-Society for Surgery of the Alimentary Tract (SSAT) Resident Research Award Selwyn M. Vickers, M.D. Curriculum Vitae 8 revised 09.19.2013 2. Lee Pederson, M.D. (1996-1998) – Gene therapy and its application to pancreatic cancer Ross-SSAT Resident Research Award SSAT Outstanding Resident Research Award Alabama Chapter of the American College of Surgeons Resident Research Award 3. Allen Pickens, M.D. (1997-1999) – The role of FAS in the oncogenesis of pancreatic cancer Ross-SSAT Resident Research Award UAB 1st Annual Resident Research Day Basic Science Research Award 4. Allen Gustin, M.D. (1998-2000) – Gene therapy application to treatment of metastatic pancreatic cancer Ross-SSAT Resident Research Award UAB Resident Research Day Outstanding Research Award 5. Peter Nagi, M.D. (2000-2002) SSAT Resident Research Award 6. Pedro Ramirez, M.D. (2002-2004) – Gene therapy for pancreatic cancer Alabama Chapter of the American College of Surgeons Resident Research Award UAB Resident Research Day Outstanding Research Award 7. L. Christopher DeRosier, M.D. (2003-2006) – Monoclonal Antibody Death Receptor Therapy UAB Resident Research Day Outstanding Research Award 8. Daniel Borja-Cacho, M.D. (2006-2008) - Role of HSP 70 in the Oncogeneric of Pancreatic Cancer 9. Mara Anonoff, M.D. (2007-2009) – Role of Triptolide in the Inhibitors and Treatment of Neuroblastoma 10. Leonard Armstrong, M.D. (2009-2011) – Development of Interferon and Bare Gene Therapy Platform for the Treatment of Pancreatic Cancer 11. Kimberly A. Clawson, M.D. (2008-present) – Effects of Minnelide on Experimental HSP 70 in Cholangiocarcinoma 12. Tara C. Krosch, M.D. (2008-present) – T32 Fellow in Surgical Oncology 13. Rohit Chugh, M.D. (2011-present) – T32 Fellow in Surgical Oncology MAJOR LECTURES AND VISITING PROFESSORSHIPS: Visiting Professor – Vanderbilt University (1997) – Gene Therapy Treatment of Pancreatic Cancer Visiting Professor – Carraway Medical Center (1997) – Gene Therapy Treatment of Pancreatic Cancer Visiting Professor – Torreon, Mexico (1998) – Basic Science Development in the Treatment of Pancreatic Cancer Selwyn M. Vickers, M.D. Curriculum Vitae 9 revised 09.19.2013 Visiting Professor – Medical College of Georgia (1998) – Novel Therapeutic Treatment of Pancreatic Cancer Visiting Professor – Baylor Medical College (1999) – “The Molecular Surgeon” Visiting Professor – University of Edinburgh Scotland, Royal Infirmary Hospital – (2000) Molecular Basis of Treatment of Pancreatic Cancer Visiting Professor – University of Glasgow, Royal Infirmary Hospital (2000) – Surgical Treatment of Chronic Pancreatitis Visiting Professor – University of Cape Town South Africa (2000) – Molecular Basis of Treatment of Bile Duct Cancer Visiting Professor – Institute of Nutricion and Medicine, Mexico City (2004, 2005) – Molecular Basis of Treatment of Pancreatic Cancer Drew Walker Visiting Professor – Meharry Medical College/Vanderbilt Medical School (2003) Maltory Lecture – National Medical Society (2002) – History Worth Revisiting But Not Repeating Visiting Professor – SUNY (2005) – Novel Therapies for the Treatment of Cholangiocarcinoma Visiting Professor – Massachusetts General Hospital (2007) – New Opportunities for the Treatment of Pancreatic Cancer: From Bench to Bedside Strauss Lecturer – University of Chicago (2007) - Owen Harding Wangensteen and the Historical Foundation of the University of Minnesota Training Program Visiting Professor – Johns Hopkins University (2008) – Missing People: Minorities in Medicine 2004 Sullivan Report: Lessons Learned from our Past, Hope for our Future Visiting Professor – University of Toledo (2008) Visiting Professor – University of Wisconsin (2008) Bruce White Lecturer – University of Indiana (2008) Presidential Session – American Surgical Congress (2009) - The Glass Ceiling: Does It Still Exist for Women and Minorities in Surgery? The Role of Critical Partnerships Drew/Syphax Lecturer – Howard University Hospital (2009) - New Opportunities for the Treatment of Pancreatic Cancer: From Bench to Bedside Isaac M. Webber Lecturer at Maine Medical Center (2010) – Pancreatic Cancer from Bench to Bedside Colin G. Thomas, Jr., Lecturer at Womack Surgical Society - University of North Carolina (2010) – Current Management of Pancreatic Cancer Selwyn M. Vickers, M.D. Curriculum Vitae 10 revised 09.19.2013 Joaquin Aldrete Visiting Professor – University of Alabama, Birmingham (2010) Keynote Speaker – Georgia Surgical Society (2010) - Current Surgical Management of Chronic Pancreatitis; Medical Leadership: The Role for Physician Leadership; Pancreatic SPORE Program: Clinical Translational Research Joel J. Roslyn Lecturer – Sixth Annual Academic Surgical Conference (2011) – Pancreatic Cancer from Bench to Bedside Nicholas Halasz Memorial Lecture – University of California, San Diego (2011) – Pancreatic Cancer from Bench to Bedside Johns Hopkins Biennial Meeting Lecturer – Novel Therapeutics for Pancreatic Cancer (2011) Joel Roslyn Visiting Professor – University of California, Los Angeles (2012) – Novel Therapeutics in Pancreatic Cancer Milford Hatcher Lecture Visiting Professor – Medical Center of Central Georgia (2012) – Novel Therapies for Pancreatic Cancer Annette L. Boman Women’s Fellowship Cancer Research Symposium Keynote Speaker – University of Minnesota, Duluth (2012) Harvard Visiting Honored Lecturer (2012) State of the Art Visiting Professorship – Eastern Virginia Medical School (2013) Muller-Jones Society Lecturer – University of Virginia Medical School (2013) GRANT SUPPORT: Current 2008 - 2013 T32 CA132715 – National Institutes of Health – Program Director (Selwyn M. Vickers, M.D.), Surgical Oncology Research Training Program ($1,165,700/5years) 2009 - 2014 P60 – National Institutes of Health – Principal Investigator (Jasjit Ahluwalia, M.D., M.P.H., M.S.), Center for Health Disparities Research, Engagement, and Training ($4,780,000/5 years) Director Education and Training Core 2009 - 2014 R01 – National Institutes of Health – Principal Investigator (Masato Yamamoto, M.D., Ph.D.), Enhanced CRAd for Pancreatic Cancer ($1,250,000/5 years) 2009-2012 RC2 – National Institutes of Health – Principal Investigator (Selwyn M. Vickers, M.D.), Enhancing Minority Participation in Clinical Trials (EMPaCT) ($4,300,000/3 years) Selwyn M. Vickers, M.D. Curriculum Vitae 11 revised 09.19.2013 2010-2015 P50 – National Institutes of Health – Principal Investigators (Donald J. Buchsbaum, Ph.D., and Selwyn M. Vickers, M.D.), UAB/UMN SPORE in Pancreatic Cancer ($8,458,130/5 years) 2011 – 2016 U24 – National Institutes of Health - Enhancing Minority Participation in Clinical Trials – Principal Investigators (Selwyn M. Vickers, M.D., Mona Fouad, M.D. ($3,750,000/5 years) 2013-2018 U54- National Institutes of Health – National Transdisciplinary Collaborative Center for African American Men’s Health – Principal Investigators: Selwyn M. Vickers, M.D. (PI), James Shikany, DrPH (Co-PI). ($13,500,000/5 years) Past 1985 The National Commonwealth Fund Research Fellow Dr. G.B. Bulkley – Principal Investigator (Selwyn M. Vickers, M.D.) – Development of Rat Model NEC ($5,000). 1994 – 1996 National Institutes of Health – Supplemental Faculty Development Award – Principal Investigator (Selwyn M. Vickers, M.D.), Reactive Oxygen Species in Vascular Disease ($100,000). 1996 – 1999 National Institutes of Health – Supplemental Faculty Development Award – Principal Investigator (Selwyn M. Vickers, M.D.), The Role of FAS in Tamoxifen Induced Apoptosis ($100,000). 1995 – 1999 RWJ 030875 – Robert Wood Johnson Faculty Development Fellowship – Principal Investigator (Selwyn M. Vickers, M.D.), The Role of FGF in Pancreatic Cancer ($375,000). 1998 - 1999 NMR Pilot Study Grant: Gene Therapy Clinical Trial – Principal Investigator (Selwyn M. Vickers, M.D.) ($5000). 2000 – 2001 DEB-98-VAP-06 – Debiopharm S.A. – Principal Investigator (Selwyn M. Vickers, M.D.) - Vapreotide in Pancreatic Surgery Study: A Double-Blind, Placebo-controlled, Randomized Study of Vapreotide to Prevent Post-Surgical Complications in Patients Undergoing Elective Pancreatic Resection ($47,500). 2000 – 2002 LF043 – Marc Lustgarten Foundation for Pancreatic Research – Application Award – Principal Investigator (David T. Curiel, M.D.) – Co-Investigator, 10% (Selwyn M. Vickers, M.D.), Pancreatic Carcinoma Specific Replicative Adenoviral Agent ($250,000). 2000-2005 K01CA83767 – National Cancer Institute, National Institutes of Health – Principal Investigator (Selwyn M. Vickers, M.D.), Activation of c-Src in Pancreatic Cancer by FGRF-1B ($719,000). Selwyn M. Vickers, M.D. Curriculum Vitae 12 revised 09.19.2013 2002-2004 RAID Clinical Trial for Enhanced Molecular Chemotherapy (Gene Therapy) for The Treatment of Pancreatic Cancer – Principal Investigator (Selwyn M. Vickers, M.D.), $200,000 - $300,000. 2003-2007 5P60MD00502 – National Center on Minority Health and Health Disparities, National Institutes of Health – Principal Investigator (Mona Fouad, Ph.D.), Regional Deep South Project Export Center of Excellence for Minority Health and Training ($4,200,000/4 years). *Selwyn M. Vickers, M.D. Principal Investigator 2003-2006 2003-2008 5P20CA101955 –National Cancer Institute, National Institutes of Health – Principal Investigator (Donald J. Buchsbaum, Ph.D.), Pancreatic Cancer SPORE – Molecular targeting in the treatment of Pancreatic Cancer ($5,000,000/5 years). *Selwyn M. Vickers, M.D. Principal Investigator 2003-2006 (now CoPI) 2003 – 2009 R01 DK063615 – National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health – Principal Investigator (Masato Yamamoto, M.D., Ph.D.), CRAd for Esophageal Adenocarcinoma ($226,732 annual direct). 2005 – 2006 5P20CA101955-03 – National Cancer Institute, National Institutes of Health – Supplement – Principal Investigator (Selwyn M. Vickers, M.D.), A Phase I Study Evaluating the Role of an Anti-Epidermal Growth Factor Receptor Antibody, C225, as a Radiosensitizer with Chemoradiation for Locally Advanced Pancreatic Cancer ($112,000). 2005 – 2007 Bristol-Myers Squibb Company – Principal Investigator (Selwyn M. Vickers, M.D.), A Phase I Study Evaluating the Role of an Anti-Epidermal Growth Factor Receptor Antibody, C225, as a Radiosensitizer with Chemoradiation for Locally Advanced Pancreatic Cancer (Study Number CA225-102) ($10,000). 2007 – 2008 R56 CA094084-06 – National Institutes of Health – Principal Investigator (Masato Yamamoto, M.D., Ph.D.), Pancreatic Cancer Imaging with Conditionally Replicative Adenovirus ($250,000 annual direct). 2007 – 2012 R01 CA124723 – National Institutes of Health – Principal Investigator (Ashok K. Saluja, Ph.D.), Inhibition of HSP70 induces apoptosis in pancreatic cancer cells ($190,000 annual direct). 2008 - 2010 R21 CA131663-01 – National Institutes of Health – Principal Investigator (Ashok K. Saluja, Ph.D.), The Role of MUC1 in the Pathogenesis of Pancreatic Cancer ($150,000 annual direct). 2008 – 2010 University of Minnesota Academic Health Center – Principal Investigator (Selwyn M. Vickers, M.D.), Enhanced CRAd for Pancreatic Cancer ($185,000). Selwyn M. Vickers, M.D. Curriculum Vitae 13 revised 09.19.2013 BIBLIOGRAPHY: PUBLISHED MANUSCRIPTS: 1. Buchman TG. Cabin DE. Vickers SM. Deutschman CS. Delgado E. Sussman MM. Bulkley GB. Molecular biology of circulatory shock. Part II. Expression of Four Groups of Hepatic Genes Is Enhanced after Resuscitation from Cardiogenic Shock. Surgery. 108(3):559-66, 1990 Sep. 2. Reilly PM. MacGowan S. Miyachi M. Schiller HJ. Vickers SM. Bulkley GB. Mesenteric Vasoconstriction in Cardiogenic Shock in Pigs. Gastroenterology. 102(6):1968-79, 1992 Jun. 3. Didolkar MS. Vickers SM. Perixiphoid Extension of the Midline Incision. J Am Coll Surg. 180(6):739-41, 1995 Jun. 4. Vickers SM. Phillips JO. Kerby JD. Bynon JS Jr. Thompson JA. Curiel DT. In vivo Gene Transfer to the Human Biliary Tract. Gene Ther. 3(9):825-8, 1996 Sep. 5. Vickers SM. Kerby JD. Smoot TM. Shumate CR. Halpern NB. Aldrete JS. Gleysteen JJ. Economics of Pancreatoduodenectomy in the Elderly. Surgery. 120(4):620-5, 1996 Oct. 6. Vickers SM. Rosenfeld M, Raben D, Sampson L. In Vitro Application of Molecular Chemotherapy in the Treatment of Pancreatic Cancer. Proceedings of International Hepatobiliary Assoc. Vol. 2: 1163-67, 1996. 7. Vickers SM. Sampson LK. Ying W. Phillips JO. Receptor-Dependent Growth Inhibition of Human Pancreatic Cancer by 9-cis-retinoic Acid. J Gastrointest Surg. 1(2):174-181, 1997 Mar. 8. Sampson LK. Vickers SM. Ying W. Phillips JO. Tamoxifen-Mediated Growth Inhibition of Human Cholangiocarcinoma. Cancer Res. 57(9):1743-9, 1997 May 1. 9. Rosenfeld ME. Vickers SM. Raben D. Wang M. Sampson L. Feng M. Jaffee E. Curiel DT. Pancreatic Carcinoma Cell Killing Via Adenoviral Mediated Delivery of the Herpes Simplex Virus Thymidine Kinase Gene. Ann Surg. 225(5):609-18, 1997 May. 10. Titus AS. Baron TH. Listinsky CM. Vickers SM. Solitary Breast Metastasis to the Ampulla and Distal Common Bile Duct. Am Surg. 63(6):512-5, 1997 Jun. 11. Vickers SM. Niederhuber JE. Hodgkin’s Disease Associated with Neurologic Paraneoplastic Syndrome. South Med J. 90(8):839-44, 1997 Aug. 12. Vickers SM. Sampson LS. Phillips JO. Eckhoff D. Kerby JD. Sekar MC. Curiel DT. Thompson JA. Adenoviral Vector Infection of the Human Exocrine Pancreas. Arch Surg. 132(9):1006-9, 1997 Sep. Selwyn M. Vickers, M.D. Curriculum Vitae 14 revised 09.19.2013 13. Pederson LC. Buchsbaum DJ. Vickers SM. Kancharla SR. Mayo MS. Curiel DT. Stackhouse MA. Molecular chemotherapy combined with radiation therapy enhances killing of cholangiocarcinoma cells in vitro and in vivo. Cancer Res. 57(19):4325-32, 1997 Oct 1. 14. Pederson LC. Vickers SM. The surgical management of chronic pancreatitis (ductal strictures). Semin Gastrointest Dis. 9(2):80-3, 1998 Apr. 15. Vickers SM. Chan C. Heslin MJ. Aldrete JS. The role of proximal pancreatic resections in the treatment of chronic pancreatitis. Proceedings of the 3rd World Congress of the International Hepatobiliary Association, Madrid, Spain, May 24-28, 1998. 16. Pickens A. Pan G. McDonald J. Vickers SM. Tamoxifen induced apoptotic cell death utilizes the Fas/Apo-1 (CD 95) pathway in human cholangiocarcinoma. Proceedings of the 3rd World Congress of the International Hepatobiliary Association, Madrid, Spain, May 24-28, 1998. 17. Pederson LC. Vickers SM. Buchsbaum DJ. Kancharla SR. Mayo MS. Curiel DT. Stackhouse MA. Combined cytosine deaminase expression, 5-fluorocytosine exposure, and radiotherapy increases cytotoxicity to cholangiocarcinoma cells. J Gastrointest Surg. 2(3):283-91, 1998 May-Jun. 18. Vickers SM. Schiller HJ. Hildreth JE. Bulkley GB. Immunoaffinity localization of the enzyme xanthine oxidase on the outside surface of the endothelial cell plasma membrane. Surgery. 124(3):551-60, 1998 Sep. 19. Baron TH. Morgan DE. Vickers SM. Endoscopic transgastric drainage of a retroperitoneal lymphocele. Gastrointest Endosc. 48(3):309-11, 1998 Sep. 20. Vickers SM. Green M, MacMillan-Crow LA Pickens A. Thompson JA. FGF-1 Induces resistance to inflammatory-mediated apoptosis in pancreatic cell line. Surgical Forum. 1998. 21. Baron TH. Vickers SM. Surgical gastrostomy placement as access for diagnostic and therapeutic ERCP. Gastrointest Endosc. 48(6):640-1, 1998 Dec. 22. Pedersen L. Lazenby A. Vickers SM. Abdominal actinomycosis secondary to foreign body perforation. Veterans Health System Journal. (3):41-4, 1998. 23. Pickens A. Vickers SM. Brown KL, Reddy VV. Thompson JA. An unusual etiology of biliary hilar obstruction and the potential role of acidic fibroblast growth factor in the development of a biliary neuroma. Am Surg. 65(1):47-51, 1999 Jan. 24. Titus AS. Pinckard NB. Cook WJ. Vickers SM. Solitary malignant peripheral nerve sheath tumor of the pancreas. Hepatogastroenterology. 46(25):514-7, 1999 Jan-Feb. 25. Vickers SM. MacMillan-Crow LA. Green M. Ellis C. Thompson JA. Association of increased immunostaining for inducible nitric oxide synthase and nitrotyrosine with fibroblast growth factor transformation in pancreatic cancer. Arch Surg. 134(3):245-51, 1999 Mar. Selwyn M. Vickers, M.D. Curriculum Vitae 15 revised 09.19.2013 26. Pan G. Vickers SM. Pickens A. Phillips JO. Ying W. Thompson JA. Siegal GP. McDonald JM. Apoptosis and tumorigenesis in human cholangiocarcinoma cells. Involvement of Fas/APO-1 (CD95) and calmodulin. Am J Pathol. 155(1):193-203, 1999 Jul. 27. Baron TH. Morgan DE. Vickers SM. Lazenby AJ. Organized pancreatic necrosis: endoscopic, radiologic, and pathologic features of a distinct clinical entity. Pancreas. 19(1):105-8, 1999 Jul. 28. Pickens A. Pan G. McDonald JM. Vickers SM. Fas expression prevents cholangiocarcinoma tumor growth. J Gastrointest Surg. 3(4):374-82, 1999 Jul-Aug. 29. Vickers SM. Chan C. Heslin MJ. Bartolucci A. Aldrete JS. The role of pancreaticoduodenectomy in the treatment of severe chronic pancreatitis. Am Surg. 65(12):1108-11, 1999 Dec. 30. Pederson LC. Buchsbaum DJ. Stackhouse MA. Curiel DT. Mayo MS. Vickers SM. Cytosine Deaminase and herpes simplex virus Thymidine Kinase Gene Expression via adenoviral infection of human cholangiocarcinoma cells occurs in the presence of human bile. Tumor Targeting. (4):1-8, 1999. 31. Chan C. Medina-Franco H. Bell W. Lazenby A. Vickers SM. Carcinoid tumor of the hepatic duct presenting as a Klatskin tumor in an adolescent and review of world literature. Hepatogastroenterology. 47(32):519-21, 2000 Mar-Apr. 32. MacMillan-Crow LA. Greendorfer JS. Vickers SM. Thompson JA. Tyrosine nitration of cSRC tyrosine kinase in human pancreatic ductal adenocarcinoma. Arch Biochem Biophys. 377(2):350-6, 2000 May 15. 33. Stackhouse MA. Pederson LC. Grizzle WE. Curiel DT. Gebert J. Haack K. Vickers SM. Mayo MS. Buchsbaum DJ. Fractionated radiation therapy in combination with adenoviral delivery of the cytosine deaminase gene and 5-fluorocytosine enhances cytotoxic and antitumor effects in human colorectal and cholangiocarcinoma models. Gene Ther. 7(12):1019-26, 2000 Jun. 34. Chan C. Bartolucci A. Vickers SM. Combined intraoperative alcohol celiac ablation and lateral pancreaticojejunostomy for chronic pancreatitis. Curr Surg. 57(6):636, 2000 Nov. 35. Gustin AN. Buchsbaum DJ. Kiss P. Elgavish G. Johnson M. Stackhouse M. Vickers SM. Detection of 5-FC to 5-FU via 19Fluorine NMR Spectroscopy (19F NMR) in the treatment of pancreatic cancer. Surgery. Vol. 6, 2000. 36. Alvarado CA. Vickers SM. Invited Critique: Adjuvant chemoradiotherapy for “Unfavorable” carcinoma of the ampulla vater: A Preliminary Report. Arch Surg. 136(1):69, 2001 Jan. 37. Heslin MJ. Medina-Franco H. Parker M. Vickers SM. Aldrete J. Urist MM. Colorectal hepatic metastases: resection, local ablation, and hepatic artery infusion pump are associated with prolonged survival. Arch Surg. 136(3):318-23, 2001 Mar. Selwyn M. Vickers, M.D. Curriculum Vitae 16 revised 09.19.2013 38. Chan C. Vilatoba M. Bartolucci A. Vickers, SM. Improved reduction in pain in chronic pancreatitis with combined intraoperative celiac axis plexus block and lateral pancreaticojejunostomy. Curr Surg. 58(2):220-2, 2001 March. 39. Vickers SM. MacMillan-Crow L. Huang Z. Thompson JA. Acidic fibroblast growth factor (FGF-1) signaling inhibits peroxynitrite-induced cell death during pancreatic tumorigenesis. Free Radic Biol Med. 30(9):957-66, 2001 May 1. 40. Gustin A. Pederson L. Chan C. Vickers SM. The role of molecular biology in the application of gene therapy strategies. World J of Surg. 26(7):854-60, 2001 Jul. 41. Wesseling JG. Bosma PJ. Krasnykh V. Kashentseva EA. Blackwell JL. Reynolds PN. Li H. Parameshwar M. Vickers SM. Jaffee EM. Huibregtse K. Curiel DT. Dmitriev I. Improved gene transfer efficiency to primary and established human pancreatic carcinoma target cells via epidermal growth factor receptor and integrin-targeted adenoviral vectors. Gene Ther. 8(13):969-76, 2001 Jul. 42. Wesseling JG. Yamamoto M. Adachi Y. Bosma PJ. van Wijland M. Blackwell JL. Li H. Reynolds PN. Dmitriev I. Vickers SM. Huibregtse K. Curiel DT. Midkine and cyclooxygenase-2 promoters are promising for adenoviral vector gene delivery of pancreatic carcinoma. Cancer Gene Ther. 8(12):990-6, 2001 Dec. 43. Miller CR. Gustin AN. Buchsbaum DJ. Vickers SM. Manne U. Grizzle WE. Cloud GA. Diasio RB. Johnson MR. Quantitation of cytosine deaminase mRNA by real-time reverse transcription polymerase chain reaction: a sensitive method for assessing 5-fluorocytosine toxicity in vitro. Anal Biochem. 301(2):189-99, 2002 Feb. 44. Umphrey HR. Wilcox CM. Vickers SM. Extrahepatic biliary cystadenoma localized to the common bile duct. Surgery. 131(5):587-8, 2002 May. 45. Vickers SM. Jhala NC. Ahn EY. McDonald JM. Pan G. Bland KI. Tamoxifen (TMX)/Fas induced growth inhibition of human cholangiocarcinoma (HCC) by gamma interferon (IFNgamma). Ann Surg. 235(6):872-8, 2002 June. 46. Gustin A. Pederson L. Miller R. Chan C. Vickers SM. Application of molecular biology studies to gene therapy treatment strategies. World J Surg. 26(7):854-60, 2002 Jul. 47. Vickers SM. Huang ZQ. MacMillan-Crow L. Greendorfer JS. Thompson JA. Ligand activation of alternatively spliced fibroblast growth factor receptor-1 modulates pancreatic adenocarcinoma cell malignancy. J Gastrointest Surg. 6(4):546-53, 2002 Jul-Aug. 48. Ahn EY. Pan G. Vickers SM. McDonald JM. IFN-gamma upregulates apoptosis-related molecules and enhances Fas-mediated apoptosis in human cholangiocarcinoma. Int J Cancer. 100(4):445-51, 2002 Aug. 49. Chhieng DC. Jhala D. Jhala N. Eltoum I. Chen VK. Vickers SM. Heslin MJ. Wilcox CM. Eloubeidi MA. Endoscopic ultrasound-guided fine-needle aspiration biopsy: a study of 103 cases. Cancer Cytopathology. 96(4):232-9, 2002 Aug. Selwyn M. Vickers, M.D. Curriculum Vitae 17 revised 09.19.2013 50. Mohadjer Y. Danner O. Vickers SM. Methemoglobinemia induced by topical benzocaine spray for feeding tube placement. Contemporary Surgery. 58(12):22-5, 2002 Dec. 51. Shore G. Gonzalez QH. Bondora A. Vickers SM. Laparoscopic vs. conventional ileocolectomy for primary Crohn disease. Arch Surg. 138(1):76-9, 2003 Jan. 52. Nagi P. Vickers SM. Davydova J. Adachi Y. Takayama K. Barker S. Krasnykh V. Curiel DT. Yamamoto M. Development of a therapeutic adenoviral vector for cholangiocarcinoma combining tumor-restricted gene expression and infectivity-enhancement. J Gastrointest Surg. 7(3):364-71, 2003 Mar-Apr. 53. Melton SM. McGwin G Jr. Cross JM. Davidson J. Waller H. Doss MW. Vickers SM. Rue LW 3rd. Common bile duct transection in blunt abdominal trauma: case report emphasizing mechanism of injury and therapeutic management. J Trauma. 54(4):781-5, 2003 Apr. 54. Huang, ZQ. Buchsbaum DJ. Raisch KP. Bonner JA. Bland KI. Vickers SM. Differential responses by pancreatic carcinoma cell lines to prolonged exposure to Erbitux (IMC-C225) anti-EGFR antibody. J Surg Res. 111(2):274-83, 2003 May. 55. Gonzalez QH. Heslin MJ. Shore G. Vickers SM. Urist MM. Bland KI. Results of long-term follow-up for trans-anal excision of rectal cancer. Am Surg. 69(8):675-8, 2003 Aug. 56. Yamamoto M. Davydova J. Wang M. Siegal GP. Krasnykh V. Vickers SM. Curiel DT. Infectivity enhanced, Cyclooxygenase-2 Promoter-Based Conditionally Replicative Adenovirus for Pancreatic Cancer. Gastroenterology. 125(4):1203-18. 2003 Oct. 57. Eloubeidi MA. Jhala D. Chhieng DC. Chen VK. Eltoum I. Vickers SM. Wilcox CM. Jhala N. Yield of endoscopic ultrasound-guided fine-needle aspiration biopsy in patients with suspected pancreatic carcinoma. Cancer. 99(5):285-92, 2003 Oct. 58. Eloubeidi MA. Iseman DT. Chen VK. Vickers SM. Wilcox CM. Prevalence and significance of periduodenal venous collaterals in patients evaluated for pancreaticobiliary disorders by endosonography. Endoscopy. 35(12):1015-9, 2003 Dec. 59. Eloubeidi MA. Chen VK. Eltoum IE. Jhala D. Chhieng DC, Jhala N. Vickers SM. Wilcox CM. Endoscopic Ultrasound-Guided Fine Needle Aspiration Biopsy of Patients with Suspected Pancreatic Cancer: Diagnostic Accuracy and Acute and 30-Day Complications. Am J Gastroenterol. 98(12):2663-8, 2003 Dec. 60. Eloubeidi MA. Chen VK. Volk AL. Jhala N. Vickers SM. Chhieng D. Recurrent metastatic Klatskin’s carcinoid tumor to celiac lymph nodes in a teenager: diagnosis by endoscopic ultrasound-guided fine needle aspiration biopsy with immunocytochemical correlation. Dig Dis Sci. 48(12):2301-5, 2003 Dec. 61. Saif MW. Joseph M. Tang S. Vickers SM. Plants B. Russo S. Retrospective Analysis of Capecitabine and Radiation Therapy in the Treatment of Pancreatic Cancer. J of App Research. 4(4):635-646, 2004. Selwyn M. Vickers, M.D. Curriculum Vitae 18 revised 09.19.2013 62. Hawn MT. Canon CL. Lockhart ME. Gonzalez QH. Shore G. Bondora A. Vickers SM. Serum Lactic Acid Determines the Outcomes of CT Diagnosis of Pneumatosis of the Gastrointestinal Tract. Am Surg. 70(1):19-24, 2004 Jan. 63. Ramirez PJ. Vickers SM. Current Status of Gene Therapy for Pancreatic Cancer. Curr Surg. 61(1):84-92, 2004 Jan-Feb. 64. Eloubeidi MA. Chen VK. Jhala NC. Eltoum IE. Jhala D. Chhieng DC, Syed SA. Vickers SM. Wilcox MC. Endoscopic ultrasound-guided fine needle aspiration biopsy of suspected cholangiocarcinoma. Clin Gastroenterol Hepatol. 2(3):209-13, 2004 March. 65. Wan M. Tang Y. Tytler EM. Lu C. Jin B. Vickers SM. Yang L. Shi X. Cao X. Smad4 protein stability is regulated by ubiquitin ligase SCF beta-TrCP1. J Biol Chem. 2004 April;279(15):14484-7. 66. Gonzalez QH. Tishler DS. Plata-Munoz JJ. Bondora A. Vickers SM. Leath T. Clements RH. Incidence of Clinically Evident Deep Venous Thrombosis after Laparoscopic Roux-en-Y Gastric Bypass. Surg Endosc. 18(7):1082-4, 2004 July. 67. Ramirez PJ. Vickers SM. Adenoviral Gene Therapy for Pancreatic Adenocarcinoma. Curr Surg. 61(4):351-8, 2004 July/August. 68. Jhala NC. Jhala D. Eltoum I. Vickers SM. Wilcox M. Chhieng DC. Eloubeidi MA. Endoscopic ultrasound guided fine needle aspiration: A powerful tool to obtain samples from small lesions. Cancer Cytopathology. 102(4):239-46, 2004 Aug. 69. Ramirez PJ. Vickers SM. Regulatory Cells. Curr Surg. 61(5):407-10, 2004 Sept-Oct. 70. Arnoletti JP. Buchsbaum DJ. Huang Z. Hawkins, AE. Kraus MH. Vickers SM. Mechanisms of Resistance to Erbitux (Anti-Epidermal Growth Factor Receptor) Combination Therapy in Pancreatic Adenocarcinoma Cells. J Gastrointest Surg. 8(8):960-9, 2004 Dec. 71. Jhala N. Vickers SM. Argani P. McDonald J. Regulators of Apoptosis in Cholangiocarcinoma. Arch Pathology & Laboratory Med. 129(4):481-6, 2005 April. 72. Hawn MT. Bian J. Leeth RR. Ritchie G. Allen N. Bland KI. Vickers SM. Impact of Obesity on Resource Utilization for General Surgical Procedures. Annals of Surgery. 241(5):821-6, 2005 May. 73. Wan M. Huang J. Jhala NC. Tytler EM. Yang L. Vickers SM. Tang Y. Lu C. Wang N. Cao X. SCFβ-TrCP1 controls Smad4 protein stability in pancreatic cancer cells. Am J Pathol. 166(5):1379-92, 2005 May. 74. Tekant Y. Davydova J. Ramirez PJ. et al. Oncolytic Adenoviral Therapy in Gallbladder Cancer. Surgery. 137:327-35, 2005 May. 75. Tempero MA. Behrman S. Ben-Josef E. Benson AB 3rd. Cameron JL. Casper ES. Hoffman JP. Karl RC. Kim P. Koh WJ. Kuvshinoff BW 2nd. Melvin WS. Muscarella P 2nd. Sasson AR. Shibata S. Shrieve DC. Talamonti MS. Tyler DS. Vickers SM. Warren RS. Willett C. Wolff Selwyn M. Vickers, M.D. Curriculum Vitae 19 revised 09.19.2013 RA; National Comprehensive Cancer Network. Pancreatic Adenocarcinoma: Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 3(5):598-626, 2005 Sept. 76. Eltoum IA. Eloubeidi MA. Chhient DC. Tamhane A. Crowe R. Jhala D. St. John KD. Wilcox CM. Siegal GP. Vickers SM. Jhala NC. Cytologic Grade Independently Predicts Survival of Patients with Pancreatic Adenocarcinoma. Am J Clin Pathol. 124(5):697-707, 2005 Nov. 77. Katasani VG. Leeth RR. Tishler DS. Leath, TD. Roy, BP. Canon CL. Vickers SM. Clements RH. Water-Soluble Upper GI Based on Clinical Findings Is Reliable to Detect Anastomotic Leaks After Laparoscopic Gastric Bypass. Am Surg. 2005 Nov;71(11):916-8. 78. Finan KR. Leeth RR. Ritchie G. Vickers SM. Hawn MT. Obesity Status and Utilization of General Surgery Resources. Am Surg. 2005 Nov;71(11):963-9. 79. Blanquicett C. Buchsbaum DJ. Saif MW. Eloubeidi M. Vickers SM. Chhieng DC. Carpenter MD. Sellers JC. Russo S. Diasio RB. Johnson MR. Antitumor Efficacy of Capecitabine and Celecoxib in Irradiated and Lead Shielded, Contralateral Human BxPC-3 Pancreatic Cancer Xenografts: Clinical Implications of Abscopal Effects in a Metastatic Model. Clinical Cancer Research. 2005 Dec;11(24):8773-81. 80. Steg A. Wang W. Blanquicett C. Grunda JM. Eltoum IA. Wang K. Buchsbaum DJ. Vickers SM. Russo S. Diasio RB. Frost AR. LoBuglio AF. Grizzle WE. Johnson MR. Multiple Gene Expression Analyses in Paraffin-Embedded Tissues by Taqman Low Density Array: Application to Hedgehog and Wnt Pathway Analysis in Ovarian Endometrioid Adenocarcinoma. J Mol Diag. 2006 Feb;8(1):76-83. 81. Allen NC. Leeth RR. Finan KR. Tischler DS. Vickers SM. Wilcox CM. Hawn MT. Outcomes of Cholecystectomy Following Endoscopic Sphincterotomy for Choledocholithiasis. J Gastrointest Surgery. 2006 Feb;10(2):292-6. 82. Eloubeidi MA, Desmond RA, Wilcox CM, Wilson RJ, Manchikalapati P, Fouad MM, Eltoum I, Vickers SM. Prognostic factors for survival in pancreatic cancer: a population-based study. Am J Surg. 2006 Sep;192(3):322-9. 83. Jhala N, Jhala D, Vickers SM, Eltoum I, Batra SK, Manne U, Eloubeidi M, Jones JJ, Grizzle WE. Biomarkers in Diagnosis of pancreatic carcinoma in fine-needle aspirates. Am J Clin Pathol. 2006 Oct;126(4):572-9. 84. Derosier LC, Huang ZQ, Sellers JC, Buchsbaum DJ, Vickers SM. Treatment With Gemcitabine and TRA-8 Anti-Death Receptor-5 mAb Reduces Pancreatic Adenocarcinoma Cell Viability In Vitro and Growth In Vivo. J Gastrointest Surg. 2006 Nov;10(9):1291-300. 85. Clements RH, Katasani VG, Palepu R, Leeth RR, Leath TD, Roy BP, Vickers SM. Incidence of vitamin deficiency after laparoscopic Roux-en-Y gastric bypass in a university hospital setting. Am Surg. 2006 Dec;72(12):1196-202; discussion 1203-4. 86. Gomez-Rivera F, Stewart AE, Arnoletti JP, Vickers S, Bland KI, Heslin MJ. Surgical treatment of pancreatic endocrine neoplasms. Am J Surg. 2007 Apr;193(4):460-5. Selwyn M. Vickers, M.D. Curriculum Vitae 20 revised 09.19.2013 87. Tzeng CW, Frolov A, Frolova N, Jhala NC, Howard JH, Buchsbaum DJ, Vickers SM, Heslin MJ, Arnoletti JP. Epidermal growth factor receptor (EGFR) is highly conserved in pancreatic cancer. Surgery. 2007 Apr;141(4):464-9. Epub 2007 Jan 22. 88. Eloubeidi MA, Varadarajulu S, Desai S, Shirley R, Heslin MJ, Mehra M, Arnoletti JP, Eltoum I, Wilcox CM, Vickers SM. A Prospective Evaluation of an Algorithm Incorporating Routine Preoperative Endoscopic Ultrasound-Guided Fine Needle Aspiration in Suspected Pancreatic Cancer. J Gastrointest Surg. 2007 Jul;11(7):813-9. 89. Tzeng C-WD, Frolov A, Frolova N, Howard JH, Vickers SM, Buchsbaum DJ, Heslin MJ, Arnoletti JP: Pancreatic cancer epidermal growth factor receptor (EGFR) intron 1 polymorphism influences postoperative patient survival and in vitro erlotinib response. Ann Surg Oncol. 2007 Jul;14(7):2150-8. Epub 2007 Apr 24. 90. Frolov A, Schuller K, Tzeng C-WD, Cannon EE, Ku BC, Howard JH, Vickers SM, Heslin MJ, Buchsbaum DJ, Arnoletti JP. ErbB3 expression and dimerization with EGFR influence pancreatic cancer cell sensitivity to erlotinib. Cancer Biol Ther. 2007 Apr;6(4):548-54. 91. Clements RH, Leeth RR, Vickers SM, Bland KI. Incorporating laparoscopic fellowship does not increase morbidity or mortality in a university-based bariatric practice. J Am Coll Surg. 2007 May;204(5):824-8. 92. Kojima K, Vickers SM, Adsay NV, Jhala NC, Kim HG, Schoeb TR, Grizzle WE, Klug CA. Inactivation of Smad4 Accelerates KrasG12D-Mediated Pancreatic Neoplasia. Cancer Res. 2007 Sep 1;67(17):8121-30. 93. DeRosier LC, Buchsbaum DJ, Oliver PG, Huang Z, Sellers JC, Grizzle WE, Wang W, Zhou T, Zinn KR, Long JW, Vickers SM. Combination treatment with TRA-8 anti-death receptor-5 antibody and CPT-11 induces tumor regression in an orthotopic model of pancreatic cancer. Clin Canc Res. 2007 Sep 15;13(18):5535s-43s. 94. Phillips PA, Dudeja V, McCarroll JA, Borja-Cacho D, Dawra RK, Grizzle WE, Vickers SM, Saluja AK. Triptolide induces pancreatic cancer cell death via inhibition of heat shock protein 70. Cancer Res. 2007 Oct 1;67(19):9407-16. 95. Tzeng CW, Frolov A, Frolova N, Jhala NC, Howard JH, Vickers SM, Buchsbaum DJ, Heslin MJ, Arnoletti JP. EGFR Genomic Gain and Aberrant Pathway Signaling in Pancreatic Cancer Patients. J Surg Res. 2007 Nov;143(1):20-6. 96. Thrall M, Jessurun J, Stelow E, Adsay NV, Vickers S, Whitson A, Saltzman D, Pambuccian S. Multicystic Adenomatoid Hamartoma of the Pancreas. A Hitherto Undescribed Pancreatic Tumor Occurring In A 3-Year-Old Boy. Pediatr Dev Pathol. 2007 Jul 17;1 [Epub ahead of print] 97. Steg A, Vickers SM, Eloubeidi M, Wang W, Eltoum IA, Grizzle WE, Saif MW, Lobuglio AF, Frost AR, Johnson MR. Hedgehog Pathway Expression in Heterogeneous Pancreatic Adenocarcinoma: Implications for the Molecular Analysis of Clinically Available Biopsies. Diagn Mol Pathol. 2007 Dec;16(4):229-237. Selwyn M. Vickers, M.D. Curriculum Vitae 21 revised 09.19.2013 98. DeRosier LC, Vickers SM, Zinn KR, Huang Z, Wang W, Grizzle WE, Sellers JC, Stockard CR, Zhou T, Oliver PG, Arnoletti JP, LoBuglio AF, Buchsbaum DJ. TRA-8 anti-DR5 monoclonal antibody and gemcitabine induce apoptosis and inhibit radiologically validated orthotopic pancreatic tumor growth. Mol Canc Ther. 2007 Dec;6(12 Pt 1):3198-207. 99. Gonzalez QH, Heslin MJ, Dávila-Cervantes A, Alvarez-Tostado J, de los Monteros AE, Shore G, Vickers SM. Primary colonic lymphoma. Am Surg. 2008 Mar;74(3):214-6. 100. Picozzi VJ, Pisters PW, Vickers SM, Strasberg SM. Strength of the Evidence: Adjuvant Therapy for Resected Pancreatic Cancer. J Gastrointest Surg. 2008 Apr;12(4):657-61. Epub 2007 Dec 22. 101. Ramirez PJ, Vickers SM, Ono HA, Davydova J, Takayama K, Thompson TC, Curiel DT, Bland KI, Yamamoto M. Optimization of Conditionally Replicative Adenovirus for Pancreatic Cancer and Its Evaluation in an Orthotopic Model. Am J Surg. 2008 Apr;195(4):481-90. 102. Vallera DA, Stish BJ, Shu Y, Chen H, Saluja A, Buchsbaum DJ, Vickers SM. Genetically designing a more potent anti-pancreatic cancer agent by simultaneously cotargeting human IL13 and EGF receptors in a mouse xenograft model. Gut. 2008 May;57(5):634-41. Epub 2008 Jan 25. 103. Morgan DE, Texada JC, Canon CL, Lockhart ME, Posey JA 3rd, Vickers SM. Multidetector Computed Tomography During Combined Therapy for Pancreatic Adenocarcinoma. Clin Gastroenterol Hepatol. 2008 Aug;6(8):842-848.e3. Epub 2008 Jun 27. Review. 104. Borja-Cacho D. Jensen EH. Saluja AK. Buchsbaum DJ. Vickers SM. Molecular Targeted Therapies for Pancreatic Cancer. Am J Surg. 2008 Sep;196(3):430-41. 105. Dudeja V, Skube S, Chugh R, Yokoyama Y, Talukdar R, Majumdar N, Borja-Cacho D, Antonoff M, Dawra R, Vickers S, Saluja A. Hsf-1 gene silencing: a potential therapeutic strategy for pancreatobiliary tumors. Abstracts of papers submitted to the 39th Annual Meeting of the American Pancreatic Association. Pancreas 2008; 37(4): 467. 106. Jensen EH, Abraham A, Habermann EB, Al-Refaie WB, Vickers SM, Virnig BA, Tuttle TM. A Critical Analysis of the Surgical Management of Early-Stage Gallbladder Cancer in the United States. J Gastrointest Surg. J Gastrointest Surg. 2009 Apr;13(4):722-7. Epub 2008 Dec 13. 107. Safo AO, Li RW, Vickers SM, Schmechel SC, Pambuccian SE. Endoscopic ultrasound-guided fine-needle aspiration diagnosis of clear-cell pancreatic endocrine neoplasm in a patient with von Hippel-Lindau disease: A case report. Diagn Cytopathol. 2009 May;37(5):365-72. Epub 2009 Feb 13. 108. Dudeja V, Mujumdar N, Phillips P, Chugh R, Borja-Cacho D, Dawra RK, Vickers SM, Saluja AK. Heat shock protein70 inhibits apoptosis in cancer cells through simultaneous and independent mechanisms. Gastroenterology. 2009 May;136(5):1772-82. Epub 2009 Feb 6. Selwyn M. Vickers, M.D. Curriculum Vitae 22 revised 09.19.2013 109. Dudeja V, Skube S, Chugh R, Yokoyama Y, Borja-Cacho D, Antonoff MB, Dawra RK, Vickers SM, Saluja AK. Silencing of heat shock factor-1 (HSF-1): a novel therapeutic modality for pancreatobiliary tumors. Journal of Surgical Research. 2009 Feb; 151(2): 251. 110. Bilimoria KY, Bentrem DJ, Lillemoe KD, Talamonti MS, Ko CY; Pancreatic Cancer Quality Indicator Development Expert Panel, American College of Surgeons. Assessment of pancreatic cancer care in the United States based on formally developed quality indicators. J Natl Cancer Inst. 2009 Jun 16;101(12):848-59. Epub 2009 Jun 9 111. Dudeja V, Vickers SM, Saluja AK. The role of heat shock proteins in gastrointestinal diseases. Gut. 2009 Jul;58(7):1000-9. Review. 112. Arrington AK, Dahlberg PS, Davydova J, Vickers SM, Yamamoto M. ERBB2 suppression decreases cell growth via apoptosis in gastrointestinal adenocarcinomas. Surgery. 2009 Aug;146(2):213-9. 113. Antonoff MB, Chugh R, Borja-Cacho D, Dudeja V, Clawson KA, Skube SJ, Sorenson BS, Saltzman DA, Vickers SM, Saluja AK. Triptolide therapy for neuroblastoma decreases cell viability in vitro and inhibits tumor growth in vivo. Surgery. 2009 Aug;146(2):282-90. 114. Kinney TP, Li R, Gupta K, Mallery S, Hunter D, Jensen E, Vickers S, Freeman ML. Therapeutic Pancreatic Endoscopy after Whipple Resection Requires Rendezvous Access. Endoscopy. 2009 Oct;41(10):898-901. Epub 2009 Sep 11. 115. Jensen EH, Abraham A, Jarosek S, Habermann EB, Al-Refaie WB, Vickers SM, Virnig BA, Tuttle TM. Lymph node evaluation is associated with improved survival after surgery for early stage gallbladder cancer. Surgery. 2009 Oct;146(4):706-11; discussion 711-3. 116. Arrington AK, Davydova J, Vickers SM, Yamamoto M. Anti-ERBB2 sh-RNA suppress both cell growth and tumor growth in ERBB2-overexpressing upper gastrointestinal adenocarcinomas. J Gastrointest Surg. 2009 Oct;13(10):1754-61. Epub 2009 Jul 15. 117. Al-Refaie WB, Gay G, Virnig BA, Tseng JF, Stewart A, Vickers SM, Tuttle TM, Feig BW. Variations in gastric cancer care: a trend beyond racial disparities. Cancer. 2010 Jan 15;116(2):465-75. Epub 2009 Nov 30. 118. Borja-Cacho D, Al-Refaie WB, Vickers SM, Tuttle T, Jensen E. Laparoscopic Distal Pancreatectomy. J Am Coll Surg 2009 Dec; 209(6): 758-765. 119. Dudeja V, Habermann EB, Zhong W, Vickers SM, Tuttle TM, Jensen EH, Al-Refaie WB. Gastric Cancer Care in the Elderly: Insights into the Generalizability of NCI Cancer Trials. J Surg Res. 2010 Feb;158(2):242-3. 120. Clawson KA, Borja-Cacho D, Antonoff MA, Saluja AK, Vickers SM. Triptolide and Trail Combination Enhances Cell Death via Apoptosis in Cholangiocarcinoma Cells. J Surg Res. 2010 Feb;158(2):340. Selwyn M. Vickers, M.D. Curriculum Vitae 23 revised 09.19.2013 121. Dudeja V, Chugh R, Bezek HM, Skube SJ, Mujumdar N, Yokoyama Y, Borja-Cacho D, Rajinder D, Vickers SM, Saluja AK. SIRT1 Gene Silencing: A Potential Therapeutic Strategy for Pancreatic Cancer. J Surg Res. 2010 Feb;158(2):339. 122. Davydova J, Gavrikova T, Brown EJ, Luo X, Curiel DT, Vickers SM, Yamamoto M. In vivo bioimaging tracks conditionally replicative adenoviral replication and provides an early indication of viral antitumor efficacy. Cancer Sci. 2010 Feb;101(2):474-81. Epub 2009 Oct 20. 123. Morgan DE, Waggoner CN, Canon CL, Lockhart ME, Fineberg NS, Posey JA 3rd, Vickers SM. Resectability of pancreatic adenocarcinoma in patients with locally advanced disease downstaged by preoperative therapy: a challenge for MDCT. AJR Am J Roentgenol. 2010 March;194:615-22. 124. Al-Refaie WB, Parsons HM, Henderson WG, Jensen EH, Tuttle TM, Vickers SM, Rothenberger DA, Virnig BA. Major Cancer Surgery in the Elderly: Results from the American College of Surgeons National Surgical Quality Improvement Program. Ann Surg. 2010 Feb; 251(2): 311-318. 125. Al-Refaie WB, Habermann EB, Dudeja V, Vickers SM, Tuttle TM, Jensen EH, Virnig BA. Extremity Soft Tissue Sarcoma Care in the Elderly: Insights into the Generalizability of NCI Cancer Trials. Ann Surg Oncol. 2010 Mar 31. [Epub ahead of print] 126. Antonoff MB, Chugh R, Skube SJ, Dudeja V, Borja-Cacho D, Clawson KA, Vickers SM, Saluja AK. Role of HSP-70 in triptolide-mediated cell death of neuroblastoma. Journal of Surgical Research. 2010 May 20. [Epub ahead of print] 127. Arnoletti JP, Frolov A, Eloubeidi M, Keene K, Posey J, Wood T, Greeno E, Jhala N, Varadarajulu S, Russo S, Christein J, Oster R, Buchsbaum DJ, Vickers SM. A Phase I Study Evaluating the Role of the Anti-Epidermal Growth Factor Receptor (EGFR) Antibody Cetuximab as a Radiosensitizer with Chemoradiation for Locally Advanced Pancreatic Cancer. Cancer Chemother Pharmacol. 2010 Jun 30. [Epub ahead of print] 128. Oh S, Stish BJ, Vickers SM, Buchsbaum DJ, Saluja AK, Vallera DA. A New Drug Delivery Method of Bispecific Ligand-Directed Toxins, Which Reduces Toxicity and Promotes Efficacy in a Model of Orthotopic Pancreatic Cancer. Pancreas. 2010 Aug; 39(4):913-922. 129. Dudeja V, Chugh RK, Sangwan V, Skube SJ, Mujumdar NR, Antonoff MB, Dawra RK, Vickers SM, Saluja AK. Pro-survival Role of Heat Shock Factor 1 (HSF1) in the Pathogenesis of Pancreatobillary Tumors. American Journal of Physiology. 2011 February 17. 130. Brand RE, Nolen BM, Zeh HJ, Allen PJ, Eloubeidi MA, Goldberg M, Elton E, Arnoletti JP, Christein JD, Vickers SM, Langmead CJ, Landsittel DP, Whitcomb DC, Grizzle WE, Lokshin AE. Serum Biomaker Panels for the Detection of Pancreatic Cancer. Clinical Cancer Research. 2011 February 15; 17 (4): 805-816. 131. Dudeja V, Habermann EB, Zhong W, Tuttle TM, Vickers SM, Jensen EH, Al-Refaie WB. Ann of Surg Oncol. 2011 Jan; 18 (1): 26-33. [Epub 2010 Jul 20] Selwyn M. Vickers, M.D. Curriculum Vitae 24 revised 09.19.2013 132. Jensen EH, Vickers SM. Maximally invasive hepatobiliary surgeon: A dying breed: Comment on “Laparoscopic vs open hepatectomy for benign and malignant tumors”. Arch Surg. 2010 Nov; 145 (11): 1118. 133. Mujumdar N, Mackenzie TN, Dudeja V, Chugh R, Antonoff MB, Borja-Cacho D, Sangwan V, Dawra R, Vickers SM, Saluja AK. Triptolide induces cell death in pancreatic cancer cells by apoptotic and autophagic pathways. Gastroenterology. 2010 Aug; 139 (2):598-608. Epub 2010 Apr 29. 134. Bellin MD, Freeman ML, Schwarzenberg SJ, Dunn TB, Beilman GJ, Vickers SM, Chinnakotla S, Balamurugan AN, Hering BJ, Radosevich DM, Moran A, Sutherland DER. Quality of Life Improves for Pediatric Patients After Total Pancreatectomy and Islet Autotransplant for Chronic Pancreatitis. Clinical Gastroenterology and Hepatology. 2011 May. 135. Soltani SM, O’Brien TD, Loganathan G, Bellin MD, Anazawa T, Tiwari M, Papas KK, Vickers SM, Kumaravel V, Hering BJ, Sutherland DER, Balamurugan AN. Severely fibrotic pancreases from young patients with chronic pancreatitis: evidence for a ductal origin of islet neogenesis. Acta Diabetologica. 2011 July. 136. Al-Refaie WB, Vickers SM, Zhong W, Parsons H, Rothenberger D, Habermann EB. Cancer trials versus the real world in the United States. Ann Surg. 2011 Sep;254(3):438-43. 137. Huang ZQ, Saluja AK, Dudeja V, Vickers SM, Buchsbaum DJ. Molecular Targeted Approaches for Treatment of Pancreatic Cancer. Curr Pharm Des. 2011 Jul 21 138. Phillips PA, Sangwan V, Borja-Cacho D, Dudeja V, Vickers SM, Saluja AK. Myricetic induces pancreatic cell death via the induction of apoptosis and inhibition of the PI3K signaling pathway. Cancer Lett Sep 28;308(2)181-8. 139. Soltani SM, O'Brien TD, Loganathan G, Bellin MD, Anazawa T, Tiwari M, Papas KK, Vickers SM, Kumaravel V, Hering BJ, Sutherland DE, Balamurugan AN. Severely fibrotic pancreases from young patients with chronic pancreatitis: evidence for a ductal origin of islet neogenesis. Acta Diabetol. 2011 Jul 20. 140. Al-Refaie WB, Vickers SM, Zhong W, Parsons H, Rothenberger D, Habermann EB. Cancer trials versus the real world in the United States. Ann Surg. 2011 Sep;254(3):438-42. 141. Huang ZQ, Saluja AK, Dudeja V, Vickers SM, Buchsbaum DJ. Molecular targeted approaches for treatment of pancreatic cancer. Curr Pharm Des. 2011;17(21):2221-38. Review. 142. Al-Refaie WB, Muluneh B, Zhong W, Parsons HM, Tuttle TM, Vickers SM, Habermann EB. Who receives their complex cancer surgery at low-volume hospitals? J Am Coll Surg. 2012 Jan;214(1):81-7. 143. Parsons HM, Habermann EB, Stain SC, Vickers SM, Al-Refaie WB. What happens to racial and ethnic minorities after cancer surgery at American College of Surgeons National Surgical Quality Improvement Program hospitals? J Am Coll Surg. 2012 Apr;214(4):539-47. Selwyn M. Vickers, M.D. Curriculum Vitae 25 revised 09.19.2013 144. Sutherland DE, Radosevich DM, Bellin MD, Hering BJ, Beilman GJ, Dunn TB, Chinnakotla S, Vickers SM, Bland B, Balamurugan AN, Freeman ML, Pruett TL. Total pancreatectomy and islet autotransplantation for chronic pancreatitis. J Am Coll Surg. 2012 Apr;214(4):409-24. 145. Armstrong L, Davydova J, Brown E, Han J, Yamamoto M, Vickers SM. Delivery of interferon alpha using a novel Cox2-controlled adenovirus for pancreatic cancer therapy. Surgery. 2012 Jul;152(1):114-22. 146. Armstrong L, Arrington A, Han J, Gavrikova T, Brown E, Yamamoto M, Vickers SM, Davydova J. Generation of a novel, cyclooxygenase-2-targeted, interferon-expressing, conditionally replicative adenovirus for pancreatic cancer therapy. Am J Surg. 2012 Jun 28. [Epub ahead of print] 147. Al-Refaie WB, Vickers SM. Are cancer trials valid and useful for the general surgeon and surgical oncologist? Adv Surg. 2012;46:269-81. 148. Markin A, Habermann EB, Chow CJ, Zhu Y, Vickers SM, Al-Refaie WB. Rurality and cancer surgery in the United States. Am J Surg. 2012 Aug 17. 149. Banerjee S, Mujumdar N, Dudeja V, Mackenzie T, Krosch TK, Sangwan V, Vickers SM, Saluja AK MUC1c Regulates Cell Survival in Pancreatic Cancer by Preventing Lysosomal Permeabilization. PLoS One. 2012;7(8):e43020. Epub 2012 Aug 13 150. Randall E. Brand, Brian M. Nolen, Herbert J. Zeh, Peter J. Allen, Mohamad A. Eloubeidi, Michael Goldberg, Eric Elton, Juan P. Arnoletti, John D. Christein, Selwyn M. Vickers, Christopher J. Langmead, Douglas P. Landsittel, David C. Whitcomb, William E. Grizzle, Anna E. Lokshin. Serum Biomarker Panels for the Detection of Pancreatic Cancer. Clin Cancer Res. 17(4): 805–816. 2012, Feb. 151. Mujumdar N, Banarjee S, Chen Z, Sangwan V, Chugh R, Dudeja V, Yamamoto M, Vickers SM, Saluja A. Triptolide activates unfolded protein response leading to chronic ER stress in pancreatic cancer cells. American Journal of Physiology. 2013 December 152. Banerjee S, Sangwan V, Vickers SM, Saluja AK. Triptolide induced cell death in pancreatic cancer is mediated by O-GlcNAc modification of transcription factor Sp1. Journal of Biological Chemistry. 2013; 288(47): 33927-38. 153. Chen Z, Sangwan V, Banerjee S, Chugh R, Dudeja V, Vickers SM, Saluja AK. Triptolide sensitizes pancreatic cancer cells to TRAIL-induced activation of the Death Receptor Pathway. Cancer Letters. 2014; epub ahead of print. 154. Banerjee S, Nomura A, Sangwan V, Chugh R, Dudeja V, Vickers SM, Saluja AK. Minnelide reduces CD133+ tumor initiating “stem-like” cells within a syngenic murine model of pancreatic ductal adenocarcinoma. In press Clinical Cancer Research. 2014. Selwyn M. Vickers, M.D. Curriculum Vitae 26 revised 09.19.2013 155. Mujumdar N, Sangwan V, Banerjee S, MacKenzie T, Dudeja V, Vickers SM, Saluja AK. Triptolide induces tumor cell death by increasing endoplasmic reticulum stress in pancreatic cancer. In Press American Journal of Physiology. 2014. 156. Vickers, S. M. and Fouad, M. N. (2014), An overview of EMPaCT and fundamental issues affecting minority participation in cancer clinical trials: Enhancing minority participation in clinical trials (EMPaCT): Laying the groundwork for improving minority clinical trial accrual. Cancer, 120: 1087–1090. doi: 10.1002/cncr.28569 157. Hawk, E. T., Habermann, E. B., Ford, J. G., Wenzel, J. A., Brahmer, J. R., Chen, M. S., Jones, L. A., Hurd, T. C., Rogers, L. M., Nguyen, L. H., Ahluwalia, J. S., Fouad, M. and Vickers, S. M. (2014), Five National Cancer Institute–designated cancer centers' data collection on racial/ethnic minority participation in therapeutic trials. Cancer, 120: 1113–1121. doi: 10.1002/cncr.28571 158. Suszynski TM, Wilhelm JJ, Radosevich DM, Balamurugan AN, Sutherland DE, Beilman GJ, Dunn TB, Chinnakotla S, Pruett TL, Vickers SM, Hering BJ, Papas KK, Bellin MD. Islet size index as a predictor of outcomes in clinical islet autotransplantation. Transplantation. 2014 Mar 11 [Epub ahead of print]. BOOKS/CHAPTERS: 1. Vickers SM, Bailey RW, Bulkley GB: Ischemic hepatitis in: Marston A, Bulkley GB, Fiddian-Green RG, Haglund UH (eds). Splanchnic Ischemia and Multiple Organ Failure pp 261-267, London, Edward Arnold, Ltd., 1989. Selwyn M. Vickers, M.D. Curriculum Vitae 27 revised 09.19.2013 2. Pederson LC and Vickers SM. A Clinical Approach to Proximal Hilar Cholangiocarcinoma and Gallbladder Carcinoma. Van Leeuwen D (ed). Cholangiocarcinoma, Pathogenesis and Diagnosis. (Book Chapter) 1998. 3. Vickers SM. Surgery of the Pancreas, 2nd Edition. Trede M and Carter DC (eds). New York, Churchill Livingstone, 1997. Book Review Archives of Surgery. 133: 909-910, 1998. 4. Vickers SM. Pancreatic Cancer: Pathogenesis Diagnosis and Treatment, 1st Edition. Reber #A, Totawa, NJ, Humana Press, 1998. Book Review Archives of Surgery. 133:1367-1368, 1998. Vickers SM. Nagi PA. Nutritional Requirements Following Cancer Treatment/Surgery. Handbook of Clinical Nutrition and Aging. Totawa, NJ, Humana Press. Chapter 20;477-86. 2004. 5. 6. Smith MD. Degiannis E. Vickers SM. Surgery for Chronic Pancreatitis. Pancreatitis and Its Complications. Totawa, NJ, Humana Press. Chapter 15:223-72. 2004. 7. Borja-Cacho D, Vickers SM. Benign Diseases of Stomach and Duodenum. R.A. Rosenthal et al. (eds). Principles and Practice of Geriatric Surgery, 2nd Edition. New York, New York, Springer Science+Business Media. Chapter 61:763-779. 2011. 8. Banerjee S. Vickers SM. Saluja, A. Molecular Mechanism of Pancreatic Carcinogenesis. D. Nageshwar Reddy (ed). Recent Advances in Pancreas. New Dehli, India, Elsevier. 88:124 2012. PUBLISHED ABSTRACTS: 1. Qadir M, Sussman MS, Vickers S, Im MJ, Manson PM, Engler RL, Bulkley GB. Mechanism of enhanced skin flap survival by xanthine oxidase inhibition: purine salvage or ablation of free radical generation (Abstract). 2. Buchman TG, Cabin DE, Vickers S, Bulkley GB. Cardiogenic (tamponade) and resuscitation increases hepatic expression of two serine protease inhibitors mRNAs. Gastroenterology. 96:A580, 1989. 3. Bailey RW, Vickers S, Porter JM, Meilahn JE, Morris JB, Sussman MS, Buchman TG, Haglund UH, Hami SR, Herlong HF, Tang WS, Bulkley GB. The development of multiple organ system failure in swine following splanchnic ischemia in response to cardiogenic shock. Gastroenterology. 96:A23, 1989. 4. Deutschman CS, Cabin DE, Delgado EM, Vickers S, Bulkley GB, Buchman TG. Differential complimentary DNA (cDNA) screening identifies induction of fibrinogen gene expression following shock/resuscitation. Anesthesiology 10:1989. 5. Vickers S, Miyachi M, Hildreth J, Baig M, Kuhajda F, Madara P, Mather I,Bulkley GB. Immunohistoaffinity localization of xanthine oxidoreductase (XOR) and histochemical discrimination of dehydrogenase (XD) from oxidase (XO) in situ. FASEB Journal 4:A896, 1990. Selwyn M. Vickers, M.D. Curriculum Vitae 28 revised 09.19.2013 6. Miyachi M, Vickers S, Bulkley GB. Quantitative histochemical localization of xanthine oxidoreductase (XOR) with discrimination of the dehydrogenase (XD) from the oxidase (XO) forms in tissue sections. Circ Shock 31:80, 1990. 7. Vickers S, Hildreth J, Kuhajda F, Madara P, Mather I, Baig M, Bulkley GB. Immunohistoaffinity localization of the xanthine oxidase in the microvascular endothelial cells of porcine and human organs. Circ Shock 31:87, 1990. Schiller HJ, Vickers S, Hildreth J, Mather I, Kahajda, Bulkley GB. Immunoaffinity localization of xanthine oxidase on the outside surface of the endothelial cell plasma membrane. Circ Shock 34:A435, 1991. (Resident’s Award Winner, Shock Society, 1991). 8. 9. Miyachi M, Vickers S, Schiller HJ, Patel P, Mather I, Hildreth J, Kuhajda F, Bulkley GB. Immunoaffinity localization of the free radical-generating enzyme xanthine oxidase in the microvascular endothelium of the porcine and human brain. Circ Shock 34:A436, 1991. 10. Vickers SM, Chan C, Heslin MJ and Aldrete JS. The Role of Pancreaticoduodenectomy in the Treatment of Severe Chronic Pancreatitis. (Abstract) 11. Pederson LC, Buchsbaum DJ, Stackhouse, MA, Curiel DT and Vickers SM. Effective Toxin Gene Expression Via Adenoviral Infection of Human Cholangiocarcinoma Cells in the Presence of Human Bile. (Abstract) 12. Pickens A, Pan G, McDonald J and Vickers SM. Involvement of FAS in Tamoxifen-Induced Apoptosis of Cholangiocarcinoma. (SSAT 1997) 13. Pederson LC, Vickers SM, Buchsbaum DJ. Kancharla SR. Mayo MS. Curiel DT. Stackhouse MA, Curiel DT, Mayo MS, Kancharla S, Bright S, Olsen C, Buchsbaum DJ. Cytosine Deaminase Gene Therapy and Fractionated Radiation Therapy Enhances Anti-Tumor Effects in Human Cholangiocarcinoma. (SSAT 1997) 14. Vickers SM, Phillips JO, Eckhoff D, Kerby JD, Thompson J and Curiel DT. Gene Transfer of a Recombinant Adenoviral Vector to the Human Biliary Tract. (Abstract) 15. Vickers SM, Pederson LC, Stackhouse MA, Douglas JT, Sosnowski B, Curiel DT and Buchsbaum DJ. Redirection of adenoviral mediated cytosine deaminase gene transfer via FGF2 receptor enhances pancreatic carcinoma and cholangiocarcinoma cytotoxicity to 5fluorocytosine conversions to 5-fluorouracil. (Abstract) 16. Gustin AN, Buchsbaum DJ, Kiss P, Elgavish G, Johnson M, Stackhouse M, Vickers SM: Detection of 5-FC to 5-FU conversion by cytosine deaminase via 19Fluorine NMR spectroscopy (19F NMR) in the treatment of pancreatic cancer. The Society of University Surgeons 61st Annual Meeting. 2000 Feb. 17. Vickers SM, MacMillan-Crow LA, Green M, Thompson JA. Alternatively Spliced FGFR-1 Isoforms Atenuate the Malignant Phenotype of FGF-1 Transformed Pancreatic Ductal Cells. (Abstract) Selwyn M. Vickers, M.D. Curriculum Vitae 29 revised 09.19.2013 18. 19. Sarr M. Traverso W. Castillo C. Aranha G. Evans D. Gibbs J. Gillanders W. Conlon K. Michelassi F. Mulholland M. Murr M. Nealon W. Pappas T. Prinz R. Shamamian P. Vickers S. Weaver s. Wilson S. Ahrendt S. Zinner M. Vapreotide, A Potent Long-Acting Somatostatin Analogue, Does Not Decrease Pancrease-Related Complications After Elective Pancreatectomy—A Multicenter, Double-Blind, Randomized Placebo-Controlled Study. Submitted to the American College of Surgeons Clinical Congress. 2002 Oct. Huang Z-Q. Buchsbaum DJ. Raisch KP. Vickers SM. Differential responses by pancreatic carcinoma cell lines to prolonged exposure to Erbitux (IMC-C225) anti-EGFR antibody. The Association for Academic Surgery 36th Annual Meeting. 2002 Nov. 20. Jhala NC. Tytler E. Vickers SM. Oeschlenger D. Grizzle WE. Heterogenous Protein Expression Pattern in Human Pancreatic Cancer Cells: Analysis by Novel Protein Chip Technology (SELDI-TOFM). Poster accepted Lab Invest and Modern Path. 2003 Jan. 21. Vickers SM. Gonzalez QH. Gomez F. Bondora A. Necrosectomy Through Cyst-Gastrostomy for the Treatment of Pancreatic Necrosis. (Abstract) Submitted to the Society of Black Academic Surgeons Scientific Seminar. 2003 April. 22. Eloubeidi MA. Chen VK. Jhala NN. Eltoum IE. Jhala D. Chhieng DC. Syed SA. Vickers SM. Wilcox CM. Endoscopic Ultrasound Guided Fine Needle Aspiration Biopsy in Patients with Suspected Cholangiocarcinoma: Diagnostic Accuracy and Impact on Management. Submitted to Digestive Disease Week Conference. 2003 May. 23. Blanquicett C. Buchsbaum DJ. Vickers SM. Sellers JC. Chieng DC. Carpenter M. Diasio RB. Johnson MR. Utilizing a pharmacogenomic approach to design treatment paradigms for pancreatic cancer. Proc Am Assoc Cancer Res (1st ed.) 44:1067, 2003. 24. Blanquicett C. Buchsbaum DJ. Vickers SM. Sellers JC. Carpenter M. Diasio RB. Johnson MR. Rationale for capecitabine (CAP) and irradiation (XRT) to treat pancreatic cancer. Proc ASCO 22:241, 2003. 25. Blanquicett C. Buchsbaum DJ. Vickers SM. Sellers JC. Chieng DC. Carpenter M. Diasio RB. Johnson MR. Utilizing a pharmacogenomic approach to design treatment paradigms for pancreatic cancer. Proc Am Assoc Cancer Res (2nd ed.) 44:926, 2003. 26. Blanquicett C. Buchsbaum DJ. Vickers SM. Sellers JC. Chieng DC. Carpenter M. Diasio RB. Johnson MR. Utilizing a pharmacogenomic approach to design treatment paradigms for pancreatic cancer. Proc Comprehensive Cancer Center 2003 Annual Research Retreat, University of Alabama at Birmingham, Birmingham, AL, 2003 Oct. 27. Arnoletti JP. Buchsbaum D. Huang Z-q. Hawkins A. Vickers S. Impaired internalization of EGFR as a mechanism for resistance to Erbitux (anti-EGFR Ab) combination therapy in BxPC3 pancreatic adenocarcinoma xenografts. The Society for Surgery of the Alimentary Tract 45th Annual Meeting. 2004 May. 28. Hawn MT. Bian J. Leeth RR. Ritchie G. Allen N. Bland KI. Vickers SM. Impact of Obesity on Operative Time: Three Surgical Procedures. Submitted to the 116th Annual Session of the Southern Surgical Association. 2004 Dec. Selwyn M. Vickers, M.D. Curriculum Vitae 30 revised 09.19.2013 29. Huang Z. Oliver PG. Ye I. Sellers J. Vickers SM. Buchsbaum DJ. Combination therapy of pancreatic cancer using TRA-8 antibody against death receptor 5 and gemcitabine induces apoptosis via different mechanisms. Proc Am Assoc Cancer Res 46, April 2005. 30. DeRosier LC. Oliver PG. Buchsbaum DJ. Vickers SM. Combination treatment with TRA-8 antibody to death receptor 5 and chemotherapy agents induces cell death in pancreatic cancer cell lines. Digestive Disease Week 2005. 2005 May. 31. Finan KR. Bian J. Leeth RR. Allen N. Ritchie G. Vickers SM. Hawn MT. Impact of Obesity on Non-Bariatric General Surgical Workload and Resource Utilization. Submitted to the 2005 Annual Meeting of the Alabama Chapter of the American College of Surgeons. 2005 Jun. 32. Buchsbaum DJ. DeRosier LC. Sellers JC. Huang Z-q. Oliver PG. Vickers SM. Treatment of pancreatic cancer with TRA-8 anti-death receptor 5 antibody in combination with chemotherapy. The 13th SPORE Investigators Workshop. 2005 Jul. 33. DeRosier LC. Buchsbaum DJ. Sellers JC. Huang ZQ. Oliver PG. Vickers SM. Treatment of pancreatic cancer with anti-death receptor antibody in combination with gemcitabine. 60th Annual Surgical Forum at the American College of Surgeons 91st Annual Clinical Congress. 2005 Oct. 34. DeRosier C. Buchsbaum DJ. Sellers JC. Huang ZQ. Oliver PG. Vickers SM. Combination of CPT-11 and anti-death receptor 5 antibody inhibits pancreatic cancer in an orthotopic tumor model. Proc Comprehensive Cancer Center 2005 Annual Research Retreat, University of Alabama at Birmingham, Birmingham, AL, 2005 Oct. 35. Schuller K. Cannon E. Frolov A. Heslin MJ. Buchsbaum DJ. Vickers S. Arnoletti P. Improved response of pancreatic adenocarcinoma cells to combined ErbB receptor molecular targeting. Proc Comprehensive Cancer Center 2005 Annual Research Retreat, University of Alabama at Birmingham, Birmingham, AL, 2005 Oct. 36. DeRosier LC. Buchsbaum DJ. Sellers JC. Huang ZQ. Oliver PG. Vickers SM. Combination of irinotecan and anti-death receptor 5 antibody inhibits pancreatic cancer in an orthotopic tumor model. The Society of University Surgeons Meeting, 2006 Feb. 37. DeRosier LC. Huang Z. Sellers J. Zinn K. Buchsbaum D. Vickers S. Combination therapy with anti-death receptor 5 antibody and gemcitabine significantly reduces pancreatic adenocarcinoma cell viability in vitro and improves survival in an orthotopic model of pancreatic cancer. The First Annual SSCI Oncology Young Investigator Research Forum, 2006 Mar. 38. Frolov A. Schuller KW. Cannon EE. Buchsbaum DJ. Vickers SM. Heslin MJ. Arnoletti P. Improved response of pancreatic adenocarcinoma cells to combined ErbB receptor molecular targeting: A role for ErbB3? Proc Am Assoc Cancer Res 47:1236, 2006. 39. Tzeng C-WD. Frolov A. Frolova N. Jhala NC. Frost AR. Howard JH. Schuller KW. Buchsbaum DJ. Vickers SM. Heslin MJ. Arnoletti JP. Pancreatic cancer EGFR pathway signaling in the absence of activating mutations: Implications for EGFR-targeted therapy. Proc Am Assoc Cancer Res 47:1240, 2006. Selwyn M. Vickers, M.D. Curriculum Vitae 31 revised 09.19.2013 40. Christein JD. Leeth RR. Murthy RK. Heslin M. Jhala NC. Arnoletti P. Vickers SM. Does margin status affect outcome after pancreaticoduodenectomy for pancreatic adenocarcinoma? Submitted to the 2006 Annual Meeting of the Alabama Chapter of the American College of Surgeons. 2006 May. 41. DeRosier LC. Huang ZQ. Sellers JC. Zinn K. Buchsbaum DJ. Vickers SM. Combination therapy with TRA-8 anti-death receptor-5 antibody significantly reduces pancreatic adenocarcinoma cell viability in vitro and growth in vivo. The Society for Surgery of the Alimentary Tract 47th Annual Meeting. 2006 May. 42. Buchsbaum DJ. DeRosier LC. Sellers JC. Vickers SM. Zinn KR. Ultrasound imaging to monitor response of orthotopic pancreatic cancer xenografts treated with TRA-8 anti-DR5 MAb and gemcitabine. J Nucl Med 47:427P-428P, 2006. 43. DeRosier LC. Vickers SM. Zinn KR. LoBuglio AF. Wang W. Buchsbaum DJ. Treatment of orthotopic pancreatic cancer xenografts with TRA-8 anti-DR5 antibody and chemotherapy. Cancer Biother Radiopharm 21:384, 2006. 44. Tzeng C-WD. Frolova N. Jhala NC. Howard JH. Schuller KW. Buchsbaum DJ. Vickers SM. Heslin MJ. Arnoletti JP. Mechanisms of aberrant epidermal growth factor receptor signaling in the absence of EGFR gene activating mutations in pancreatic cancer patients. Proc Comprehensive Cancer Center 2006 Annual Research Retreat. University of Alabama at Birmingham, Birmingham, AL, 2006 Oct. 45. Clements RH. Leeth RR. Bland KI. Vickers SM. Incorporating Laparoscopic Fellowship Does Not Increase Morbidity or Mortality in a University-based Bariatric Practice. Submitted to the 118th Annual Session of the Southern Surgical Association. 2006 Dec. 46. DeRosier L. Buchsbaum D. Sellers J. Huang Z. Oliver P. Wang W. Zinn K. Vickers S. Combination treatment with an agonistic anti-death receptor-t antibody (TRA-8) and irinotecan (CPT-11) increases survival in an orthotopic model of pancreatic cancer. Submitted to the 118th Annual Session of the Southern Surgical Association. 2006 Dec 47. Long JW. DeRosier LC. Vickers SM. Sellers J. Wang W. Arnoletti JP. Buchsbaum DJ. TRA-8 (TRAIL-R2 antibody) based combination chemotherapy produces a survival benefit in a pancreatic cancer orthotopic model. Submitted to the 2nd Annual Academic Surgical Congress. 2007 Feb. 48. DeRosier LC, Buchsbaum DJ, Sellers J, Huang ZQ, Oliver PG, Wang W, Zinn K, Vickers SM. Treatment with a Monoclonal Death Receptor-5 Antibody and Irinotecan Increases Survival in a Radiologically Verified Model of Pancreatic Cancer. Submitted to the 2nd Annual Academic Surgical Congress. 2007 Feb. 49. Tzeng CD. Frolov A. Howard JH. Vickers SM. Buchsbaum DJ. Heslin MJ. Arnoletti JP. Analysis of aberrant epidermal growth factor receptor (EGFR) pathway signaling in pancreatic Selwyn M. Vickers, M.D. Curriculum Vitae 32 revised 09.19.2013 50. cancer patients: Implications for anti-EGFR therapy. Submitted to the 2nd Annual Academic Surgical Congress. 2007 Feb. Dudeja V. Phillips P. Dawra R. Vickers S. Saluja A. Heat Shock Protein 70 (HSP70) Over Expression Stabilizes Lysosomes and Confers Resistance to Apoptosis in Pancreatic Cancer Cells. Submitted to the 2nd Annual Academic Surgical Congress. 2007 Feb. 51. Dudeja V. Phillips P. Dawra R. Vickers S. Saluja A. Heat Shock Protein 70 (HSP70) Confers Resistance to Apoptosis in Pancreatic Cancer Cells by Modulation of Intracellular Calcium. Submitted to the 2nd Annual Academic Surgical Congress. 2007 Feb. 52. Tzeng CD. Frolov A. Howard JH. Vickers SM. Buchsbaum DJ. Heslin MJ. Arnoletti JP. Pancreatic cancer epidermal growth factor receptor (EGFR) intron 1 polymorphism influences clinical outcome and response to erlotinib. Submitted to The Society of Surgical Oncology Annual Meeting. 2007 Mar. 53. Clawson K, Vickers SM, Borja-Cacho D, Mujumdar N, Chugh R, Antonoff M, Bezek H, Saluja A. Triptolide Sensitizes Cholangiocarcinoma Cells to Trail-Induced Apoptosis by Inhibiting the Expression of HSP-70 and XIAP. Submitted to the Society of Black Academic Surgeons Annual Meeting. 2010 April. POSTER EXHIBITS: 1. Gonzalez QH. Plata-Munoz JJ. Bondora A. Vickers SM. Clements, RH. Incidence of Deep Venous Thrombosis (DVT) in Patients Undergoing Laparoscopic Roux-en-Y Gastric Bypass. Accepted for Poster Presentation. 2003 Society for American Gastrointestinal Endoscopic Surgeons (SAGES) Scientific Session and Postgraduate Courses. 2003 Mar. 2. Clements RH. Gonzalez QH. Leath T. Vickers SM. Gastrointestinal Symptoms are More Severe in Preoperative Morbidly Obese Patients. Accepted for Poster Presentation. 2003 Society for American Gastrointestinal Endoscopic Surgeons (SAGES) Scientific Session and Postgraduate Courses. 2003 Mar. 3. Christein JD. Leeth RR. Murthy RK. Heslin M. Jhala NC. Arnoletti JP. Vickers SM. Biological Markers as Predictors of Outcome and Margin Status for Pancreatic Adenocarcinoma after Pancreaticoduodenectomy. Accepted for Poster Presentation. 2006 Congress of the American Hepato-Pancreato-Biliary Association. 2006 Mar. 4. Ramirez P. Christein JD. Leeth RR. Jhala NC. Arnoletti P. Heslin M. Vickers SM. Does Margin Status Affect Survival after Pancreaticoduodenectomy for Pancreatic Head Adenocarcinoma? Accepted for Poster Presentation. 2006 Annual Meeting of The Pancreas Club, Inc. 2006 May. ORAL PRESENTATIONS: 1. Baltimore Academy of Surgery, Resident Research Award presentation, “Roeulyution of Xanthine Oxidase in the Human Heart”, 1989. Selwyn M. Vickers, M.D. Curriculum Vitae 33 revised 09.19.2013 2. 3. Society of University Surgeons, “Localization of Xanthine Oxidase on the Outer Surface of Endothelial Cells”, 1991. Alabama Chapter of the American College of Surgery, “Pancreatoduodenectomies in the Elderly”, 1994. 4. Society for Surgery of the Alimentary Tract, “The Role of Retinoic Acid in the Treatment of Pancreatic Cancer”, 1995. 5. Southern Surgical Association, “Adenoviral HSV-TK Killing of Pancreatic Cancer”, 1995 (discussant). 6. Central Surgical Association, “Pancreatoduodenectomy in the Elderly”, 1995. 7. Society of Surgery of the Alimentary Tract, “Retinoic Acid Inhibition of Pancreatic Cancer”, 1995. 8. Alabama Chapter of the American College of Surgery, “Molecular Chemotherapy for the Treatment of Pancreatic Cancer”, 1995. 9. Society of Black Academic Surgeons, “Gene Therapy for Pancreatic Cancer”, 1995. 10. Grand Rounds, Vanderbilt Department of Surgery, “The Role of FGF in Pancreatic Cancer”, 1996. 11. VA Surgeons Association, “The Role of FGF-1 in Pancreatic Cancer”, 1997. 12. Visiting Professor - Medical College of Georgia, “Gene Therapy for Pancreatic Cancer”, 1998. 13. Visiting Professor – Mexican Gastroenternal Society – Torreon, Mexico, “Gene Therapy for the Treatment of Pancreatic Cancer”, 1998. 14. Visiting Professor – Mexican College of Surgeons, “The Role of Pancreatico-duodenectomy in the Treatment of Chronic Pancreatitis” – Leon, Mexico, 1998. 15. American College of Surgeons (Surgical Forum), “FGF-1 Produces Resistance to Inflammatory Mediated Apoptosis”, 1998. 16. Molecular Surgeon – Baylor College of Medicine – “Overexpression of FGF-1, FGF-2 and FGFR1-2 in Pancreatic Cancer: Implications for Treatment”- Houston, TX, 1999. 17. Southern Research Symposium, Tuskegee University, “Gene Therapy.” 2002 Jul. 18. Meharry Medical/Vanderbilt – March 2003 New Paradigm for Treatment of Cholangiocarcinoma. 19. Society for Surgery of the Alimentary Tract, “Mechanisms of Resistance to Erbitux (AntiEpidermal Growth Factor Receptor) Combination Therapy in Pancreatic Adenocarcinoma Cells”, 2004. Selwyn M. Vickers, M.D. Curriculum Vitae 34 revised 09.19.2013 20. National Institute of Medical Sciences and Nutrition “Salvador Subirán,” “Colorectal Carcinoma.” 2005 Jan. 21. Congress of the American Hepato-Pancreato-Biliary Association, “Cystic Pancreatic Neoplasms: Selective Observation.” 2005 Apr. 22. Healthy Congregations Healthy Communities Program, “Colorectal Cancer.” 2005 Oct. 23. University of Alabama School of Medicine, “Looking for Your First Job.” 2005 Nov. 24. University of Alabama School of Medicine, “Minorities in Medicine.” 2006 Feb. 25. University of Alabama School of Medicine, “Strategies for a Successful Academic Research Career.” 2006 Feb. 26. Congress of the American Hepato-Pancreato-Biliary Association, “Etiology and Pathogenesis of Primary Sclerosing Cholangitis.” 2006 Mar. 27. The Cleveland Clinic, “Prognostic Factors for Survival in Pancreatic Cancer: A Population-Based Study.” 2006 May. 28. Minneapolis Surgical Society, “Multi-Modality Treatment of Pancreatic Cancer.” 2006 Nov. 29. University of Minnesota Chapter of Alpha Omega Alpha Induction Banquet. 2006 Nov. 30. Minnesota Association of Black Physicians. 2006 Dec. 31. Northwestern College Commencement Address. 2007 May. 32. Halsted Society. 2007 Sept. 33. University of Wisconsin Madison, “Treatment of Pancreatic Cancer from Bench to Bedside”. 2008 May. 34. University of Minnesota Masonic Cancer Center, “Translating Laboratory Research into Patient Treatment II”. 2009 April 35. Southern Surgical Association, “Long Term Outcomes of Total Pancreatectomy and IntraPortal Islet Auto-Transplantation for Hereditary/ Genetic Pancreatitis”. 2013 Dec. Selwyn M. Vickers, M.D. Curriculum Vitae 35 revised 09.19.2013