BIBLIOGRAPHY John W. Severinghaus, M.D., F.R.C.A., Dr. Med. H.C. 1 Severinghaus JW, Ferrebee JW: Calcium determination by flame photometry; method for serum, urine, and other fluids. J Biol Chem 187:621-630, 1950 2 Severinghaus JW: Electrophrenic respirator: description of portable all-electronic apparatus. Anesthesiology 12:123-128, 1951 3 Severinghaus JW: Device whereby circle rebreathing system may be instantaneously interchanged with nonrebreathing system. Anesthesiology 14:413-415, 1953 4 Nims RG, Severinghaus JW, Comroe JH Jr: Reflex hyperpnea induced by papaverine acting upon the carotid and aortic bodies. J Pharmacol Ther 109:58-61, 1953 5 Bartels J, Severinghaus JW, Forster RE, Briscoe WA, Bates DV: Respiratory dead space measured by single breath analysis of oxygen, carbon dioxide, nitrogen or helium. J Clin Invest 33:41-58, 1954 6 Severinghaus JW: Rate of uptake of nitrous oxide in man. J Clin Invest 33:1183-1189, 1954 7 Severinghaus JW, Stupfel M: Respiratory dead space increase following atropine in man and atropine, vagal or ganglionic blockade and hypothermia in dogs. J Appl Physiol 8:81-87, 1955 8 Dripps RD, Severinghaus JW: General anesthesia and respiration. Physiol Rev 35:741-777, 1955 9a Severinghaus JW, Stupfel MA: Augmentation de L'espace mort respiratoire anatomique chez le chien en hypothermie experimentale. Anesthesie et Analgesie, (Paris) 12:859-864,1955 9b Severinghaus JW, Stupfel MA: Augmentation de L'espace mort respiratoire anatomique apres injection d'atropine chez l'homme et le chien et en hypothermie experimentale. Anesthesie et Analgesie, (Paris) 12: 864869, 1955 10a Severinghaus JW, Stupfel MA: Review and appraisal of physicochemical and physiological effects of hypothermia. In: Physiology of Induced Hypothermia. Edited by Dripps RD. Publication 451, NAS-NRC, Washington, D.C. 1956, pp 279-283 10b Severinghaus JW, Stupfel MA: Respiratory physiologic studies during hypothermia. In: Physiology of Induced Hypothermia. Edited by Dripps RD. Publication 451, NAS-NRC, Washington, D.C. 1956, pp 52-58 11 Severinghaus JW, Stupfel MA, Bradley AF Jr: Accuracy of blood pH and Pco2 determinations. J Appl Physiol 9:189-196, 1956 12 Severinghaus JW, Stupfel MA, Bradley AF Jr: Variations of serum carbonic acid pK with pH and temperature. J Appl Physiol 9:197-200, 1956 13. Severinghaus JW: Effect of temperature on Pco2 and Po2 of blood in vitro. J Appl Physiol 9:201-204, 1956 14 Stupfel MA, Severinghaus JW: Internal body temperature gradients during anesthesia and hypothermia and effect of vagotomy. J Appl Physiol 9:380-386, 1956 15 Severinghaus JW, Stupfel MA: Effects of hypothermia on pulmonary function. Fed Proc 15:168, 1956 (Abstract) 16 Hebert CL, Severinghaus JW, Radigan LR: Management of patients during hypothermia. Anesth Anal 36:24-31, 1957 17 Severinghaus JW, Stupfel MA: Alveolar dead space as an index of distribution of blood flow in pulmonary capillaries. J Appl Physiol 10:335-348, 1957 18 Severinghaus JW, Stupfel MA, Bradley AF Jr: Alveolar dead space and arterial to end-tidal carbon dioxide differences during hypothermia in dog and man. J Appl Physiol 10:349-355, 1957 19 Severinghaus JW: The Telecor: An esophageal probe monitoring device. Anesthesiology 18:145-149, 1957 20 Severinghaus JW, DeBacker L: Device for transoral topical anesthesia. Anesthesiology 18:507-508, 1957 21a Severinghaus JW: Anaeroid manometer for arterial blood pressure. Anesthesiology 18:906, 1957 21b Severinghaus JW: Adaptation of Jefferson Ventilator for use with circle filter. Anesthesiology 18:649-651, 1957 22 Severinghaus JW, Cullen SC: Depression of myocardium and body oxygen consumption with fluothane. Anesthesiology 19:165-177, 1958 23 Severinghaus JW: Oxyhemoglobin dissociation curve correction for temperature and pH variation in human blood. J Appl Physiol 12:485-486, 1958 24a Severinghaus JW, Bradley AF Jr: Electrodes for blood Po2 and Pco2 determination. J Appl Physiol 13:515520, 1958 24b Severinghaus JW, Bradley AF Jr: Electrodes for blood Po2 and Pco2 determination. Printed by GPO, "Exhibit, FASEB, 1958". 25 Severinghaus JW: Temperature gradients during hypothermia. Annals of New York Acad Sci 80:515-521, 1959 26 Severinghaus JW: Respiration and hypothermia. Annals New York Acad Sci 80:384-394, 1959 27 Severinghaus JW: Recent developments in blood O2 and CO2 electrodes. In: A Symposium on pH and Blood Gas Measurements. Edited by Woolmer R. Churchill Ltd, London, 1959, pp 126-142 28 Severinghaus JW: Respiratory dead space: Man Tables 47, 48, 49, 50, 51 and 52; Blood gas transport Tables 64, 65, 70. In: Handbook of Respiration. National Research Council. Edited by Dittmer DS, Grebe RM. Saunders WB, Philadelphia, 1958 29 Severinghaus JW: Respiratory system: Methods, gas analysis. In: Medical Physics, Volume III. Edited by Glasser O. Yearbook Publishers, Chicago, 1960, pp 550560 30 Severinghaus JW: CO2 Spannung und Perfusion in Gewebe. Der Anaesthesist 9:50-55, 1960 31 Severinghaus JW, Swenson E, Finley TN, Lategola MT: Rapid shift of ventilation from unperfused regions of lung. Fed Proc 19:378, 1960 (Abstract) 32 Mitchell RA, Massion W, Carman CT, Severinghaus JW: Fourth ventricle respiratory chemosensitivity and the area postrema. Fed Proc 19:374, 1960 (Abstract) 33 Adams JE, Severinghaus JW: Oxygen tension of human cerebral gray and white matter. Physiologist 3:5, 1960 (Abstract) 34 Finley TN, Swenson EW, Clements JA, Gardner RE, Wright RR, Severinghaus JW: Changes in mechanical properties, appearance and surface activity of extracts of one lung following occlusion of its pulmonary artery in the dog. Physiologist 3:36, 1960 (Abstract) 35 Guy EP, Finley TN, Severinghaus JW: Relationship of respiration to directly measured brain CO2 tension. Anesthesiology 21:102, 1960 (Abstract) 36 Swenson EW, Finley TN, Severinghaus JW: Persistent hypoventilation in one lung following ligation of its pulmonary artery. Clin Res 8:113, 1960 (Abstract) 37 Severinghaus JW: CO2 electrode for monitoring satellite ambient CO2 . Closed Circuit Respiratory Systems Symposium, WADD Technical Report 60-574:49, 1960 38 Severinghaus JW: Methods of measurement of blood and gas carbon dioxide during anesthesia. Anesthesiology 21:717-726, 1960 39 Severinghaus JW, Swenson EW, Finley TN, Lategola M, Williams J: Unilateral hypoventilation produced in dogs by occluding one pulmonary artery. J Appl Physiol 16:5360, 1961 40 McAleavy JC, Way WL, Altstatt AH, Guadagni NP, Severinghaus JW: The effect of Pco2 on the depth of anesthesia. Anesthesiology 22:260-264, 1961 41 Massion W, Mitchell RA, Severinghaus JW: Respiratory chemosensitivity of the area postrema in the fourth ventricle. Anesthesiology 22:137, 1961 (Abstract) 42 Eger EI II, Severinghaus JW: Rate of rise of PACO2 in the apneic anesthetized patient. Anesthesiology 22:419425, 1961 43 Severinghaus JW, Larson CP Jr, Eger EI II: Correction factors for infrared carbon dioxide pressure broadening by nitrogen, nitrous oxide, and cyclopropane. Anesthesiology 22: 429-432, 1961 44 Mitchell RA, Loeschcke HH, Massion WH, Severinghaus JW: Physiologic significance of superficial medullary respiratory chemosensitivity. Physiologist 4:74, 1961 (Abstract) 45 Finley TN, Guy EP, Severinghaus JW: Calculation of the Pco2 of the central CO2 chemoreceptors before and after diamox administration. Physiologist 4:34, 1961 (Abstract) 46 Severinghaus JW: Respiration. In: Annual Review of Physiology, 1962; 24:421-470, 1962. 47 Severinghaus JW, Mitchell RA: Ondine's Curse - Failure of respiratory center automaticity while awake. Clin Res 10:122, 1962 (Abstract) 48 Eger EI II, Larson CP Jr, Severinghaus JW: Solubility of halothane in rubber, soda lime, and various plastics. Anesthesiology 23:356-359, 1962 49 Eger EI II, Johnson EA, Larson CP Jr, Severinghaus JW: The uptake and distribution of intravenous ether. Anesthesiology 23:647-650, 1962 50 Larson CP Jr, Eger EI II, Severinghaus JW: The solubility of halothane in blood and tissue homogenates. Anesthesiology 23:349-355, 1962 51 Adams JE, Severinghaus JW: Oxygen tension of human cerebral gray and white matter. J Neurosurg 19(11):959963, 1962 52 Larson CP Jr, Eger EI II, Severinghaus JW: Ostwald solubility coefficients for anesthetic gases in various fluids and tissues. Anesthesiology 23:686-689, 1962 53 Severinghaus JW: Continuously recording ventimeter. Anesthesiology 23:582-583, 1962 54 Larson CP Jr, Severinghaus JW: Postural variations in dead space and CO2 gradients breathing air and O2 . J Appl Physiol 17:417-420, 1962 55 Rapaport E, Severinghaus JW: Pulmonary circulation. In: Blood Vessels and Lymphatics. Edited by Abramson DI. New York Academic Press, 1962, pp 306-310 56 Mitchell RA, Richardson BW, Severinghaus JW: Location of medullary CO2 chemosensitivity in cats. Physiologist 5:185, 1962 (Abstract) 57 Severinghaus JW: Electrodes for blood and gas Pco2 , Po2 , and blood pH. Acta Anesth Scand Suppl 11:207220, 1962 58 Severinghaus JW, Swenson EW, Finley TN, Lategola M: Shift of ventilation produced by unilateral pulmonary artery occlusion. Med Thorac 19:298-301, 1962 59 Severinghaus JW, Richardson B: Effect of very high Pco2 on cerebral blood flow and intracranial pressure. Acta Anest Scand Suppl 12:60, 1962 (Abstract) 60 Severinghaus JW, Mitchell RA; Regulation of respiration. Acta Anesth Scand Suppl 12:11, 1962 (Abstract) 61 Mitchell RA, Carman CT, Severinghaus JW, Richardson BW, Singer MM, Shnider SM: Stability of cerebrospinal fluid (H+) in chronic acid-base disturbance of blood. Clin Res 9:120, 1963 (Abstract) 62 Severinghaus JW, Mitchell RA, Richardson BW, Singer MM: CSF pH in man during acclimatization to high altitude. Clin Res 11:118, 1963 (Abstract) 63 Severinghaus JW, Mitchell RA, Richardson BW, Singer MM: CSF pH in man during acclimatization to high altitude. Fed Proc 22:223, 1963 (Abstract) 64 Severinghaus JW: Role of lung factors. In: Uptake and Distribution of Anesthetic Agents. Edited by Papper, Kitz. McGraw Hill, 1963, pp 59-71 65 Mitchell RA, Loeschcke HH, Severinghaus JW, Richardson BW, Massion WH: Regions of respiratory chemosensitivity on the surface of the medulla. Annals New York Acad Sci 109:661-681, 1963 66 Mitchell RA, Loeschcke HH, Massion WH, Severinghaus JW: Respiratory responses mediated through superficial chemosensitive areas on the medulla. J Appl Physiol 18:523-533, 1963 67 Severinghaus JW, Mitchell RA: Evidence for active transport regulation of CSF pH and its effect on the regulation of respiration. J Clin Invest 42:977, 1963 (Abstract) 68 Severinghaus JW: High-temperature operation of oxygen electrode giving fast response for respiratory gas sampling. Clin Chem 9:727-733, 1963 69 Severinghaus JW, Mitchell RA, Richardson BW, Singer MM: Respiratory control at high altitude suggesting active transport regulation of CSF pH. J Appl Physiol 18:1155-1166, 1963 70 Severinghaus JW, Mitchell RA: The role of cerebrospinal fluid in the respiratory acclimatization to high altitude in Man. In: The Physiological Effects of High Altitude. Edited by Weihe WH. Pergamon Press Ltd, Oxford, 1964, pp 273-288 71 Severinghaus JW, A Carcelen B: Cerebrospinal fluid in man native to high altitude. J Appl Physiol 19:319-321, 1964 72 Severinghaus JW: Active transport regulation of CSF H+ with altitude acclimatization hypocapnia despite alkalization. Fed Proc 23:259, 1964 (Abstract) 72reject CSF HCO3- reduction during hyperventilation with constant plasma HCO3-. Singer, M M, Severinghaus JW, Mitchell RA, Munson ES. Subm JAP Aug 1964, finally rejected 73 Severinghaus JW, Mitchell RA, Singer MM; Altitude acclimatization despite alkalization. Clin Res 12:125, 1964 (Abstract) 74 Mitchell RA, Severinghaus JW: Role of cerebrospinal fluid in the regulation of respiration with particular reference to acclimatization at high altitude. Med Thorac (Unpublished) 75 Eger EI II, Severinghaus JW: Effect of uneven pulmonary distribution of blood and gas on induction with inhalation anesthetics. Anesthesiology 25:620-626, 1964 76 Mitchell RA, Bainton CR, Severinghaus JW, Edelist G: Respiratory response and CSF pH during disturbances in blood acid-base balance in awake dogs with denervated aortic and carotid bodies. Physiologist 7:208, 1964 (Abstract) 77 Bainton CR, Severinghaus JW, Carcelen A: Loss of hypoxic respiratory drive as a cause of "chronic mountain sickness" in Andean natives. Physiologist 7:83, 1964 (Abstract) 78 Bainton CR, Carcelen A, Severinghaus JW: Carotid chemo-receptor insensitivity in Andean natives. J Physiol 177:30-31P, 1964 (Abstract) 79 Severinghaus JW, Brandstater BB, Chiodi H, Eger EI II: Cerebral blood flow in chronic hypoxia. Acta Anesth Scand Suppl 15:96, 1964 (Abstract) 80 Mitchell RA, Severinghaus JW: Cerebrospinal fluid and the regulation of respiration. In: Physiology for Physicians, Vol 3, No 3, 1965, Amer Phys Soc. Also reprinted in: Anesth and Analg 46(1):134-141, 1967 81 Severinghaus JW: Role of cerebrospinal fluid pH in normalization of cerebral blood flow in chronic hypocapnia. Acta Neurol Scand Suppl 14:116-120, 1965 82 Mitchell RA, Carman CT, Severinghaus JW, Richardson BW, Singer MM, Shnider S: Stability of cerebrospinal fluid pH in chronic acid-base disturbances in blood. J Appl Physiol 20:443-452, 1965 83 Severinghaus JW, Larson CP Jr: Respiration in Anesthesia. In: Handbook of Physiology, Respiration II, Amer Physiol Soc, Washington DC, 1965, pp 1219-1264 84 Severinghaus JW: Electrochemical gradients for hydrogen and bicarbonate ions across the blood-CSF barrier in response to acid-base balance changes. In: Cerebrospinal Fluid and the Regulation of Ventilation. Edited by Brooks C, Kao F, Lloyd B. Blackwell Scientific Publications, Oxford, 1965, pp 247-258 85 Severinghaus JW: Bronchial muscle control. Acta Anesth Scand 15:48-51, 1965 86 Severinghaus JW: Design of capillary pH electrode incorporating an open liquid junction and reference electrode in a single unit. Scand J Clin and Lab Invest 17:614-616, 1965 87 Severinghaus JW: Blood gas calculator. J Appl Physiol 21:1108-1116, 1966 88 Severinghaus JW, et al: Statement on acid-base terminology. Report of ad hoc committee of New York Acad Aci Sci Conference, (Nov. 23-24, 1964). Anesthesiology 27:6-12, 1966 89 Severinghaus JW, Chiodi H, Eger EI II, Brandstater BB, Hornbein TF: Cerebral blood flow in man at high altitude. Circ Res 19:274-282, 1966 90 Severinghaus JW: Oxygen dissociation curve slide rule, with the new pH, base excess, and temperature correction. Physiologist 8:271, 1965 (Abstract) 91 Severinghaus JW: Blood gas concentrations. In: Handbook of Physiology, Respiration II, Amer Physiol Soc, Washington DC, 1965, pp 1475-1487. 92 Severinghaus JW: Anesthesia and related drug effects. In: Fundamentals of Hyperbaric Medicine. Nat Acad Sci Nat Res Counc, Washington DC, pp 115-127, 1966. Also reprinted as: Hyperbaric Oxygenation: Anesthesia and Drug Effects. Anesthesiology, 26:812-824, 1965 93 Severinghaus JW: Regulation of pH on the cerebral cortex. J Physiol 181:35P, 1965 (Abstract) 94 Astrup P, Engel K, Severinghaus JW, Munson ES: The influence of temperature and pH on the dissociation curve of oxyhemoglobin of human blood. Scand J Clin and Lab Invest 17:515-523, 1965 95 Saidman LW, Eger EI II, Munson ES, Severinghaus JW: A method for determining solubility of anesthetics utilizing the Scholander apparatus. Anesthesiology 27:180-184, 1966 96 Severinghaus JW: The regulation of respiration at rest. In: Breathlessness. Edited by Howell, Campbell. Blackwell Scientific Publications, Oxford, 1966, pp 85-92 97 Severinghaus JW: Site and mode of action of CO2 on cerebral blood flow in man. Fed Proc 25:461, 1966 (Abstract) 98 Eisele JH, Ritchie BC, Severinghaus JW: Effect of stellate ganglion blockade upon the hyperpnea of exercise. Clin Res 14:181, 1966 (Abstract) 99 Eger EI II, Babad AA, Regan MJ, Larson CP Jr, Shargel R, Severinghaus JW: Delayed approach of arterial to alveolar nitrous oxide partial pressures in dog and man. Anesthesiology 27:288-297, 1966 100 Severinghaus JW, Bainton CR, Carcelen A: Respiratory insensitivity to hypoxia in chronically hypoxic man. Resp Physiol 1:308-334, 1966 101 Eger EI II, Brandstater BB, Saidman LJ, Regan MJ, Severinghaus JW, Munson ES: Equipotent alveolar concentrations of methoxyflurane, halothane, diethyl ether, fluorexene, cyclopropane, xenon, and nitrous oxide in the dog. Anesthesiology 26:771-777, 1965 102 Naeraa N, Petersen ES, Boye E, Severinghaus JW: pH and molecular CO2 components of the Bohr effect in human blood. Scand J Clin Lab Invest 18:96-102, 1966 103 Severinghaus JW: Measurements of blood gases: Po2 and Pco2 . Annals New York Acad Sci 148:115-132, 1968 104 Eisele JH, Ritchie BC, Severinghaus JW: Effect of stellate ganglion blockade on the hyperpnea of exercise. J Appl Phys 22:966-969, 1967 105 Severinghaus JW, Lassen N: Step hypocapnia to separate arterial from tissue Pco2 in the regulation of cerebral blood flow. Circ Res 20:272-278, 1967 106 Sørensen SC, Severinghaus JW, Cruz J, Whayne TF Jr, Carcelen A: Respiratory sensitivity to hypoxia during and after chronic hypoxia. Fed Proc 26:665, 1967 (Abstract) 107 Cotev S, Lee J, Severinghaus JW: Effect of acetazolamide on cerebral blood flow and cerebral tissue Po2 . Anesthesiology 29:471-477, 1968 108 Lee J, Cotev S, Severinghaus JW: The effect of ventilation and diamox (acetazolamide) on cerebral blood flow in chronic respiratory acidosis. Anesthesiology 29:203, 1968 (Abstract) 109 Sørensen SC, Severinghaus JW: Respiratory insensitivity to hypoxia persisting after correction of Fallot's tetralogy. Physiologist 10:309, 1967 (Abstract) 110 Whayne TF Jr, Severinghaus JW: Experimental hypoxic pulmonary edema in the rat. Physiologist 10:342, 1967 (Abstract) 111 Severinghaus JW: A Flame for Hypnos. Forward in Applied Respiratory Physiology. Edited by Nunn JF. Butterworths, London, 1969. Revised, 1977 (112 deleted) 113 Severinghaus JW, Cotev S, Hamilton FN: Carbonic acid as an intermediate in brain decarboxylation. Fed Proc 27:401, 1968 114 Milledge JS, Iliff LD, Severinghaus JW: The site of vascular leakage in hypoxic pulmonary edema. Proceedings of the International Union of Physiological Sciences, Abstracts Vol, XXIV International Congress, 7:885, 1968 (Abstract) 115 Cotev S, Severinghaus JW: The role of CSF pH in management of respiratory problems. Anesth and Analg 48:42-47, 1969 116 Sørensen SC, Severinghaus JW: Respiratory sensitivity to acute hypoxia in man born at sea level living at high altitude. J Appl Physiol 25:211-216, 1968 117 Sørensen SC, Severinghaus JW: Irreversible respiratory insensitivity to acute hypoxia in man born at high altitude. J Appl Physiol 25:217-220, 1968 118 Sørensen SC, Severinghaus JW: Respiratory insensitivity to acute hypoxia persisting after correction of tetralogy of Fallot. J Appl Physiol 25:221-223, 1968 119 Whayne TF Jr, Severinghaus JW: Experimental hypoxic pulmonary edema in the rat. J Appl Physiol 25:729-732, 1968 120 Severinghaus JW, Cotev S: Carbonic acidosis and cerebral vasodilation after Diamox. International Symposium on "CSF and CBF", Scand J Lab and Clin Invest Suppl 102,1:E, 1968 (Abstract) 121 Cotev S, Cullen D, Severinghaus JW: Cerebral ECF acidosis induced by hypoxia at normal and low Pco2 . International Symposium on "CSF and CBF", Scand J Lab and Clin Invest Suppl 102, III:E, 1968 (Abstract) 122 Severinghaus JW, Ponten U: Discussion and comments to Section I on CSF pH. International Symposium on "CSF and CBF", Scand J Lab and Clin Invest Suppl 102, I:1, 1968 123 Severinghaus JW, Lassen NA: Cerebral blood flow control by arterial and not by tissue Pco2 as evidenced from CBF changes after step hypocapnia. International Symposium on "CSF and CBF", Scand J Lab and Clin Invest Suppl 102, VIII:K, 1968 124 Severinghaus JW: Outline of H+ - blood flow relationships in brain. International Symposium on "CSF and CBF", Scand J Lab and Clin Invest Suppl 102, VIII:K, 1968 125 Severinghaus JW: International Symposium on "CSF and CBF": A report. Anesthesiology 29:1232-1234, 1968 126 Eisele JH, Pegg J, Severinghaus JW: Ventilatory response to hypoxia in acutely polycythemic dogs. J Appl Physiol 26:757-759, 1969 127 Sørensen SC, Milledge JS, Severinghaus JW: Cerebral anaerobic metabolism and ventilatory acclimatization to chronic hypoxia. Fed Proc 28:447, 1969 (Abstract) 128 Severinghaus JW, Hamilton FN, Cotev S: Carbonic acid production and the role of carbonic anhydrase in decarboxylation in brain. Biochem J 114:703-705, 1969 129 Kronenberg RS, Hamilton FN, Gabel RA, Hickey RF, Read DJC, Severinghaus JW: Quantitation of respiratory response to hypoxia in man. Clin Res 17;416, 1969 (Abstract) 130 Hornbein TF, Severinghaus JW: Carotid chemoreceptor response to hypoxia and acidosis in cats living at high altitude. J Appl Physiol 27:837-839, 1969 131 Ehrenfeld WK, Hamilton FN, Larson CP Jr, Hickey RF, Severinghaus JW: Effect of CO2 and systemic hypertension on downstream cerebral arterial pressure during carotid endarterectomy. Surgery 67:87-96, 1970 132 Severinghaus JW, Hamilton FN: End tidal gas sampler. J Appl Physiol 28:244, 1970 133 Severinghaus JW: Revisions and preparations of Tables 31, 52, 69a and 69b, 70a and 70b, 75a and 75b, and 76. Handbook on Respiration and Circulation. Altman, Dittmer ed.. FASEB Office of Biol. Handbooks. 1971 134 Wade JG, Larson CP Jr, Hickey RF, Ehrenfeld WK, Severinghaus JW: Effect of carotid endarterectomy on carotid chemoreceptor and baroreceptor function in man. New England J Med 282:823-829, 1970 135 Sørensen SC, Severinghaus JW: The effect of cerebral acidosis on the CSF - blood potential difference. Am J Physiol 219:68-71, 1970 136 Severinghaus JW, Del Rio C, Pegg H, Eisele JH, Sørensen SC: Effects of acetazolamide on cerebral blood flow and oxygen delivery during acclimatization to high altitude. AF 41 (609)-3134, March 1967 137 Kronenberg RS, Safar P, Lee J, Wright FJ, Noble WH, Hickey RS, Wahrenbrock EA, Nemoto EM, Severinghaus JW: Pulmonary artery pressure and alveolar gas exchange during acclimatization to altitude. Clin Res 18:190, 1970 (Abstract) 138 Cullen D, Cotev S, Severinghaus JW, Eger EI II: The effects of hypoxia and isovolemic anemia on the halothane requirement (MAC) of dogs. II. The effects of acute hypoxia on halothane requirement and cerebral - surface Po2 , Pco2 , pH and HCo3-. Anesthesiology 32:35-45, 1970 139 Wahrenbrock EA, Carrico CJ, Amundsen DA, Trummer MJ, Severinghaus JW: Increased atelectatic pulmonary shunt during hemorrhagic shock in dogs. J Appl Physiol 29:615-621, 1970 140 Behar JG, Severinghaus JW: Calibration and a correction of blood O2 content measured by Po2 after CO saturation. J Appl Physiol 29:413, 1970 141 Bainton CR, Severinghaus JW: Modification of Radiometer BMS-3 electrode system to improve thermal stability. Anesthesiology 33:548:550, 1970 142 Severinghaus JW: Proton veils and the three cornered stat. Alfred Benzon Symposium III. In: Ion Homeostasis of the Brain, Edited by Siesjo BK, Sørensen SC, 1970, pp 172-174 143a Severinghaus JW, Nemoto EM, Hoff JT: The CO2 shuttle in cerebral arteriolar ECF H+ control. In: Cerebral Blood Flow and Intracranial Pressure, Proc 5th Int Symp, Roma-Siena, Part I. Eur Neurol 6:56-59, 1971 143b Severinghaus JW, Nemoto EM, Hoff JT: The CO2 shuttle in cerebral arteriolar ECF H+ control. Panminerva Medica 13:162-163, 1971 144 Raymond LW, Dolan W, Dutton R, Hoff JT, Weiskopf RB, Severinghaus JW: Pulmonary function and gas exchange during altitude hypoxia (AH). Clin Res 19:147, 1971 (Abstract) 145 Nemoto EM, Severinghaus JW: The stereospecific influx permeability of rat blood - brain - barrier (BBB) to lactic acid (LA). Clin Res 19:146, 1971 (Abstract) 146 Nemoto EM, Hoff JT, Severinghaus JW: Lactate uptake by brain and entry into CSF with sustained high blood lactate in dogs. Fed Proc 30:365, 1971 (Abstract) 147 Weiskopf RB, Severinghaus JW: Diffusing capacity of the lung for CO in man during accute acclimation to 14,246 feet. Clin Res 19:193, 1971 (Abstract) 148 Severinghaus JW, Bradley AF: Blood Gas Electrodes, or What the Instructions Didn't Say. 2nd Edition, Radiometer, Copenhagen, 1971 149 Severinghaus JW: New physiological observations on the effects of anoxia. Dansk Anaesthesiologisk Selskab, Nordisk Medicin 85:754-761, 1971 150 Kronenberg RB, Gabel RA, Severinghaus JW: Respiratory response to hypoxia in obesity before and after weight reduction. Clin Res 19,2:514, 1971 (Abstract) 151 Raymond LW, Weiskopf RB, Wright FJ, Kronenberg RS, Noble WH, Severinghaus JW: Respiratory response to hypoxia and CO2 in awake and anesthetized dogs. Clin Res 19:518, 1971 (Abstract) 152 Severinghaus JW: Transarterial Leakage: A Possible Mechanism of High Altitude Pulmonary Edema. Ciba Symposium on High Altitude Physiology: Cardiac and Respiratory Aspects. Edited by Porter R, Knight J. 1971, pp 61-77 153 Roughton FJW, Severinghaus JW: Accurate determination of O2 dissociation curve of human blood above 98.7% saturation with data on O2 solubility in unmodified human blood from 0° to 37°C. J Appl Physiol 35:861-869, 1973 154 Noble WH, Severinghaus JW:182 Thermal and conductivity curves for rapid quantitation of pulmonary edema. J Appl Physiol 32:770-775, 1972 155 Severinghaus JW, Catron CS, Noble WH: A focusing electrode bridge for unilateral lung resistance. J Appl Physiol 32:526-530, 1972 156 Severinghaus JW, Weiskopf RB, Nishimura M, Bradley AF: Oxygen electrode errors due to polarographic reduction of halothane. J Appl Physiol 31:640-642, 1971 157 Kronenberg RS, Safar P, Lee J, Wright FJ, Noble WH, Wahrenbrock EA, Hickey RS, Nemoto EM, Severinghaus JW: Pulmonary artery pressure and alveolar gas exchange in man during acclimatization to 12,470 feet. J Clin Invest 50:827-837, 1971 158 Raymond LW, Severinghaus JW: Static pulmonary compliance of man during altitude hypoxia. J Appl Physiol 31:785-787, 1971 159 Weiskopf RB, Nishimura M, Severinghaus JW: The absence of an effect of halothane on blood hemoglobin O2 equilibrium in vitro. Anesthesiology 35:579-581, 1971 160 Nemoto EM, Hoff JT, Severinghaus JW: Cerebral lactate (LA) metabolism in insulin-induced hypoglycemic dogs. Physiologist 14:202, 1971 (Abstract) 161 Weiskopf RB, Severinghaus JW: Diffusing capacity of the lung for CO in man during acclimatization to 14,246 feet. J Appl Physiol 32:285-289, 1972 162 Severinghaus JW: Electrical measurement of pulmonary edema with a focusing conductivity bridge. Proceedings of the Physiological Society, 19-20, February 1971. J Physiol 215:53-55, 1971 163 Severinghaus JW: Hypoxic respiratory drive and its loss during chronic hypoxia. Clin Physiol (Japan) 2:57-79, 1972 164 Raymond LW, Weiskopf RB, Halsen MJ, Goldfien A, Eger EI II, Severinghaus JW: Helium - oxygen (He-O2 ) Breathing: Cardiovascular effects and possible mechanism. Clin Res 20:173, 1972 (Abstract) 165 Severinghaus JW: Table 77 in Respiration and Circulation. Edited by Altman PL, Dittmer DS. Federation of American Societies for Experimental Biology, Bethesda, Maryland, 1971, pp 205 166 Weiskopf RB, Severinghaus JW: Lack of effect of high altitude on hemoglobin oxygen affinity. J Appl Physiol 33:276-277, 1972 167 Severinghaus JW: International Symposium on Cerebral Blood Flow Regulation Acid-Base and Energy Metabolism in Acute Brain Injuries. Anesthesiology 36:414-416, 1972 168 Severinghaus JW, Roughton FJW, Bradley AF: Alfred Benzon Symposium IV: "Oxygen Dissociation Curve Analysis at 98.7-99.6% Saturation". In: Oxygen Affinity of Hemoglobin and Red Cell Acid Base Status. Edited by Rørth, Astrup P, 1971, pp 65-72 169 Roughton FJW, DeLand EC, Kernohan JC, Severinghaus JW: Alfred Benzon Symposium IV: "Some Recent Studies of the Oxyhaemoglobin Dissociation Curve of Human Blood under Physiological Conditions and the Fitting of the Adair Equation to the Standard Curve". In: Oxygen Affinity of Hemoglobin and Red Cell Acid Base Status. Edited by Rørth and Astrup P, 1971, pp 73-81 170 Raymond LW, Weiskopf RB, Halsey MJ, Goldfien A, Eger EI II, Severinghaus JW: Possible mechanism for the antiarrhythmic effect of helium in anesthetized dogs. Science 176:1250-1252, 1972 171 Severinghaus JW: Percent regulation as an index of CO2 buffering in vivo and in vitro. Scand J Clin Invest 29:467, 1972 172 Kronenberg RB, Hamilton FN, Gabel RA, Hickey RB, Read DJC, Severinghaus JW: Comparison of three methods for quantitating response to hypoxia in man. Resp Physiol 16:109-125, 1972 173 Severinghaus JW: Central causes of post-operative apnea. In Anesthesiology. Edited by Miyazaki, Iwatsuki, Jujita. Exerpta Medica Fnd, Amsterdam 1973 (Proc. V World Congr, Anes) pp 102-103 (Abstract) 174 Gabel RA, Kronenberg RS, Severinghaus JW: Vital capacity breaths of 5% or 15% CO2 in N2 or O2 to test carotid chemosensitivity. Resp Physiol 17:195-208, 1973 175 Safar P, Nemoto EM, Severinghaus JW: Pathogenesis of central nervous system disorder during artificial hyperventilation in compensated hypercarbia in dogs. Crit Care Med 1:5-16, 1973 176 Severinghaus JW: Chemical Regulation of Respiration. 1973 Annual Refresher Course Lectures, Amer Soc Anesth Ann Mtg, October 7-11, 1973, San Francisco 177 Nemoto EM, Severinghaus JW: Stereospecific permeability of rat blood-brain barrier to lactic acid. Stroke 5:81-84, 1974 178 Severinghaus JW: Note on metabolic alkalosis and regulation of respiration. Collected letters, Communications in Anesthesiology, Vol 3, pp 17, March 1973 179 Severinghaus JW: Symposium on the Anesthetist and the Lung. Reports of Scientific Meetings. Edited by Cohen EN. Anesthesiology 36:523-525, 1972 180a Severinghaus JW: Hypoxia: From Mountaintop to Bedside. In: Advances in Respiratory Care and Physiology. Edited by Caldwell, Moya, Thomas Springfield, pp 189-41, 1973 180b Severinghaus JW: The Control of Respiration and the Effects of Drugs. In: Advances in Respiratory Care and Physiology. Edited by Caldwell, Moya, Thomas Springfield, pp 53-56, Discussion p57-70, 1973 181 Severinghaus JW: "Chemical Control: A summary of the session". In: Cerebral Circulation and Metabolism. Edited by Langfit et al, Springer Verlag, New York, 1974 182 Severinghaus JW: Medicion del Contenido de Oxigeno en la sangre con un Electrodo Po2 . Instit Boliv Biol Altura 4:38-42, 1972 183 Severinghaus JW: Ventilation and Anesthesia Dangerous Interactions. In: Physiological Basis of Anaesthesiology. Edited by Mushin WW, Severinghaus JW, Tiengo M, Gorini S, Piccin Medical Books, Padua, 1975, pp 201-219 184 Sørensen SC, Lassen NA, Severinghaus JW, Coudert J, Paz-Zamora MP: Cerebral glucose metabolism and cerebral blood flow in high altitude residents. J Appl Physiol 37:305-310, 1974 185 Nemoto EM, Hoff JT, Severinghaus JW: Lactate uptake and metabolism by brain during hyperlactatemia and hypoglycemia. Stroke 5:48-53, 1974 186 Weiskopf RB, Raymond LW, Severinghaus JW: Effects of halothane on canine respiratory responses to hypoxia with and wihout hypercarbia. Anesthesiology 41:350-360, 1974 187 Honda Y, Watanabe S, Hasegawa S, Myojo S, Takizawa H, Sugita T, Kimura K, Hasegawa T, Kuriyama T, Saito Y, Katsuki H, Severinghaus JW: Respiration in man after chronic glomectomy. In: Morphology and Mechanisms of Chemoreceptors. Edited by Paintal AS. Patel Chest Inst, Delhi, 1974, pp 147-155 188 Sørensen SC, Lassen NA, Severinghaus JW, Coudert J, Paz-Zamora M: Metabolismo de la glucosa cerebral y debito sanguineo cerebral en los residentes de las grandes alturas. Instituto Boliviano de Biologia de la Altura (IBBA) 5:20-28, 1973 189 Severinghaus JW: Carbon dioxide transport. In: Carbon Dioxide and Metabolic Regulation. Edited by Nahas, Schaefer, Springer-Verlag, New York, 1974, pp 138-143 190 Kronenberg RS, Gabel RA, Severinghaus JW: Normal chemoreceptor function in obesity before and after ileal bypass surgery to force weight reduction. Am J Med 59:349-353, 1975 191 Ozanne GM, Vilnis V, Severinghaus JW: Implications of O2 wave shapes and synchrony for regulation of cerebral microcirculation. In: Blood Flow and Metabolism of the Brain. Edited by Harper M, et al, Churchill Livingstone, Edinburgh, 1975, pp 9.3-9.7 (Proc 7th Int Congr CBF) 192 Overland ES, Ozanne GM, Severinghaus JW: A single breath method for determining lung weight and pulmonary blood flow from the differential uptake of two soluble gases. Physiologist 18:341, 1975 (Abstract) 193 Severinghaus JW: Coupling mechanisms: Flow to Function and Metabolism in Brain - A general discussion. In: Brain Work. Edited by Ingvar D, Lassen N, Academic Press, New York, 1975, pp 503-517 (Alfred Benzon Symposium VIII) 194 Severinghaus JW: Analog computer for base excess and HCo3- from pH and Pco2 electrodes. IEEE Trans Biomed Eng 23:77-81, 1976 195 Severinghaus JW: Current Research in Anesthesiology: Central Nervous System. pp13-16. Research Objectives in Respiration, pp 67-69. In: Anesthesiology, Its Expanding Role in Medicine. Edited by Black EA, Deming P. DHEW Publ. No. NIH 76-918, Oct 10-11, 1974 196 Severinghaus JW, Ozanne GM, Overland ES: A single breath method for determining lung weight and pulmonary blood flow from the differential uptake of two soluble gases. Am Soc Anes Annual Meeting, Chicago, 1975, pp 77 (Abstract) 197. Deleted (Chapter written on Blood Gas Measurement for Larson&Woolman book) 198 Severinghaus JW: Proposed standard determination of ventilatory responses to hypoxia and hypercapnia in man. Chest 70:129-131, 1976 199 Severinghaus JW: Acid Base Balance Nomogram - A Boston Copenhagen Detente. Anesthesiology 45:539541, 1976. 200 Louderbough HG, Ozanne G, Severinghaus JW: Lung weight and pulmonary blood flow determination in man and dogs by soluble gas uptake. Fed Proc 35:729, 1976 (Abstract) 201 Becker LD, Paulson BA, Miller RD, Severinghaus JW, Eger EI: Biphasic respiratory depression after fentanyldroperidol or fentanyl alone used to supplement nitrous oxide anesthesia. Anesthesiology 44:291-295, 1976 202 Severinghaus JW, Ozanne G, Massuda Y: Measurement of the ventilatory response to hypoxia. Chest 70:121-124, 1976 203 Pitts LH, Severinghaus JW, Mitchell RA, Hoff JT: The role of increased intracranial pressure in the production of neurogenic pulmonary edema. In: Intracranial Pressure II. Edited by Lundberg, Ponten V, Brock M. SpringerVerlag, Berlin, New York, 1979, pp 319-323 204 Severinghaus JW: Chemical regulation of ventilation: Who needs it? Editorial, New Eng J Med, 295:895-896, 1976 205 Severinghaus JW: Reye's syndrome and Ondine's curse. Editorial, West J Med 126:137-138, 1977 206 Crawford RD, Severinghaus JW, Moyers FR, Louderbough HC: CSF pH during acute and chronic exposure to hypoxia in man. Fed Proc 36:426, 1977 (Abstract) 207 Honda Y, Watanabe S, Hasegawa S, Myojo S, Takizawa T, Sugita T, Kimura K, Hasegawa T, Kuriyama T, Saito Y, Katsuki H Severinghaus JW: Breathing without carotid chemorecptors in man. In: Acid Base Homeostasis of the Brain Extracellular Fluid and the Respiratory Control System. Edited by Loeschcke H. Symposium Bochum, March 1975. Georg Thieme Publishers, Stuttgart, pp 88-94, 1976 208 Overland, E, Severinghaus JW. Noncardiac pulmonary edema. In: Advances in Internal Medicine. Edited by Stollerman GH. 23:307-326, 1978 209 Crawford RD, Severinghaus JW, Moyers JR, Louderbough HC: CSF Alkalosis at Altitude: Role of spinal cord vasodilation. Am Rev of Resp Dis, May 1977 (Abstract) 210 Severinghaus JW: Acid-Base Balance Nomogram. In: Human Health and Disease. Edited by Altman, P, Katz D, 2:192-194, FASEB 1977 211 Severinghaus JW, Crawford RD: Carotid Chemoreceptor Role in CSF Alkalosis at Altitude. Chest 73:249-251, 1978 212 Severinghaus JW: Editorial "Acid Base Balance". Communications in Anesthesiology. Edited by Sechzer P., Dec. 31, 1976, pp 111 213 Cherniack, N. et al (11 authors, including Severinghaus). Methods of Measuring ventilatory responses to hypoxia and hypercapnia. Am Rev of Resp Dis 115:177-181, 1977 214a Severinghaus JW, Ozanne GM, Louderbough H: Measurement of lung weight and cardiac output by single breath and rebreathing methods with a mass spectrometer. Acta Anaesth Scand 70:161-164, 1978 214b Severinghaus JW, Ozanne GM: Multi-operating room monitoring with one mass spectrometer. Acta Anaesth Scand 70:186-187, 1978 215a Severinghaus JW, Peabody JL, Thunstrom AM, Stafford MS: Transcutaneous oxygen measurement: Calibration, analysis and electrode stabilization methods. Acta Anaesth Scand 70:180-182, 1978 215b Severinghaus JW, Crawford RW: Regulation of Respiration. Acta Anaesth Scand 70:188-191, 1978 216 Severinghaus JW: Pulmonary vascular function. Am Rev of Resp Disease 115:149-158, 1977 217 Berger AJ, Mitchell RA, Severinghaus JW: Regulation of Respiration. N Eng J Med, 297:92-97, 138-143 and 194-201, July 14, 21 and 28, 1977. 218 Honda Y, Watanabe S, Hashizume I, Satomura Y, Hata N. Sakakibara Y, Severinghaus JW: Hypoxic chemosensitivity in asthmatic patients: Two decades after carotid body resection. J Appl Physiol 46:632-638, 1979 219 Severinghaus JW: Transcutaneous (non-invasive) measurement of arterial Pco2 . ASA Abstract, Sept 1977 220 Severinghaus JW: Medullary respiratory chemoreceptors: Implications of their response time to step hypercapnia. Physiologist 20:85, 1977 (Abstract) 221 Severinghaus JW: Correspondence: The BostonCopenhagen Detente (Letter to Editor). Anesthesiology 47:233-234, 1977 222 Severinghaus JW, Peabody J, Thunstrom A, Eberhard P, Zappia E (eds.): Workshop on Methodologic Aspects of Transcutaneous Blood Gas Analysis. Acta Anaesth Scand Suppl 68:1-144, 1978 223 Eberhard P, Severinghaus JW: Measurement of heated skin O2 diffusion conductance and Po2 sensor induced O2 gradient. Acta Anaesth Scand Suppl 68:1-3, 1978. 224 Severinghaus JW, Stafford M, Thunstrom A: Estimation of skin metabolism and blood flow with tcPo2 and tcPco2 electrodes by cuff occlusion of the circulation. Acta Anaesth Scand Suppl 68:9-15, 1978 225 Severinghaus JW: Alkaline chloride-free oxygen electrolytes. Acta Anaesth Scand Suppl 68:73-75, 1978 226 Peabody JL, Willis M, Severinghaus JW: Characteristics of non-aqueous electrolytes for transcutaneous oxygen. Acta Anaesth Scand Suppl 68:49-54, 1978 227 Thunstrom A, Severinghaus JW: The use of concentrated NaNo3 in tcPo2 electrodes to diminish O2 consumption and dehydration drift. Acta Anaesth Scand Suppl 55-62, 1978 228 Severinghaus JW, Thunstrom A: Problems of calibration and stabilization of tcPo2 electrodes. Acta Anaesth Scand Suppl 68:68-72, 1978 229 Severinghaus JW, Stafford M, Bradley AF: tcPco2 electrode design, calibration and temperature gradient problems. Acta Anaesth Scand Suppl 68:118-122, 1978 230 Severinghaus JW, Crawford RD: Carotid chemoreceptor role in CSF alkalosis at altitude. In: The Regulation of Respiration during Sleep and Anesthesia. Edited by Fitzgerald RS, Gautier H, Lahiri S. New York, Plenum Publishing Corp, 1978, pp 163-172 231a Crawford RD, Severinghaus JW: CSF pH and ventilatory acclimatization to altitude. J Appl Physiol, 45:275-283, 1978 232b Severinghaus JW, Crawford R, Irsigler G, Stafford MJ: The role of the carotid bodies to respiratory regulation studied by altitude acclimatization, metabolic acidosis and denervation. Resp Circ (Japan) 28:25-27, 1980 232 Irsigler GB, Stafford MJ, Severinghaus JW: Relationship of CSF pH to O2 and CO2 responses in metabolic acidosis and alkalosis in humans. Physiologist 21:58, 1978 (Abstract) 233 Severinghaus JW: Simple, accurate equations for human blood O2 dissociation computations. J Appl Physiol.: Respirat. Environ. Exercise Physiol. 46:599-602, 1979 233b Severinghaus JW: Simple, accurate equations for human blood O2 dissociation computations. J. Appl Physiol .: Respirat. Environ. Exercise Physiol. 46:599-602, 1979. REVISIONS 1999, 2002, 2007 234 Piernan S, Roizen MF, Severinghaus JW: O2 analyzer dangerous: Senses N2O as battery fails. Anesthesiology 50:146-149, 1979 235 Severinghaus JW, Ozanne GM, Louderbough HC, Overland ES, Stafford MJ: Lung water and cardiac output determination by noninvasive trace gas analysis of dual breathholds in a single breath. In: Progress in Respiration Research: Biomedical Engineering and Data Processing in Pneumonology, Volume 11. Edited by Matthys H. Basel, S. Karger, 1979, pp 280-296 236 Honda Y, Myojo S, Hasegawa S, Hawegawa T, Severinghaus JW: Decreased exercise hyperpnea in patients with bilateral carotid chemoreceptor resection. J Appl Physiol 46:908-912, 1979 293 237 Severinghaus JW: Current trends in continuous blood gas monitoring. Biotelemetry and Patient Monitoring. 6:915, 1979 238 Irsigler GB, Stafford MJ, Severinghaus JW: Relationship of CSF pH, O2 and CO2 responses in metabolic acidosis and alkalosis in humans. J Appl Physiol 48:355-362, 1980 239 Irsigler GB, Severinghaus JW: Clinical problems of ventilatory control. Annual Rev of Med 31:109-126, 1980 240 Severinghaus JW: Pathophysiologic aspects of the regulation of respiration. Bull Royal Acad Med Bel 134(5):261-271, 1979 241 Peabody JL, Willis MM, Gregory GA, Severinghaus JW: Reliability of skin (tc)PO2 electrode heating power as a continuous noninvasive monitor of mean arterial pressure in sick newborns. In: Continuous Transcutaneous Blood Gas Monitoring. Edited by Huch A, Huch R, Lucey JF, The National Foundation-March of Dimes. Birth Defects: Original Article Series, Vol XV-No 4. New York, A.R. Liss, Inc., 1979, pp 127-133 242 Versmold HT, Tooley WH: Increase of skin O2 diffusion resistance with birthweight. In: Continuous Transcutaneous Blood Gas Monitoring. Edited by Huch A, Huch R, Lucey JF, The National Foundation-March of Dimes. Birth Defects: Original Article Series, Vol XV-No 4. New York, A.R. Liss, Inc., 1979, pp 271-272 243 Severinghaus JW, Bradley AF, Stafford MJ; Transcutaneous PCO2 electrode design with internal silver heat path. In: Continuous Transcutaneous Blood Gas Monitoring. Edited by Huch A, Huch R, Lucey JF, The National Foundation-March of Dimes. Birth Defects: Original Article Series, Vol XV-No 4. New York, A.R. Liss, Inc., 1979, pp 265-270 244 Thunstrom AM, Stafford MJ, Severinghaus JW: A two temperature, two PO2 method of estimating the determinants of tcPO2 . In: Continuous Transcutaneous Blood Gas Monitoring. Edited by Huch A, Huch R, Lucey JF, The National Foundation-March of Dimes. Birth Defects: Original Article Series, Vol XV-No 4. New York, A.R. Liss, Inc., 1979, pp 167-182 245 Ingvar MC, Feustel PJ, Brenneman L, Severinghaus JW: Local cerebral blood flow and oxygen availability measured with the same 25 micron electrodes in cat cortex before and after middle cerebral artery ligation at altered Pco2 levels. Acta Neuro Scand Suppl 72:276277, 1979 246 Severinghaus JW, Ozanne GM, Young WG, Mazzie WJ: Multiplexed mass spectrometer operating room (OR) monitoring system. In: Proceedings: Association for the Advancement of Medical Instrumentation, 15th Annual Meeting, San Francisco, 1980. Published by AAMI, Arlington, 1980, pp 189 (Abstract) 247 Severinghaus JW: Experiments with combined tcPo2 tcPco2 electrodes. In: Proceedings: Association for the Advancement of Medical Instrumentation, 15th Annual Meeting, San Francisco, 1980. Published by AAMI, Arlington, 1980 pp 190 (Abstract) 248 Feustel PJ, Ingvar MC, Severinghaus JW: The effect of barbiturates on cerebral oxygen availability (aO2 ) and local blood flow (lCBF) during middle cerebral artery occlusion (MCAO). Fed Pro 39:383, 1980 249 Kagawa S, Stafford MJ, Waggener TB, Severinghaus JW: No effect of naloxone on hypoxic ventilatory depression in adults. Physiologist 23:139, 1980 (Abstract) 250 Ozanne GM, Young WG, Mazzie WJ, Severinghaus JW: Multipatient anesthetic mass spectrometry: Rapid analysis of data stored in long catheters. Anesthesiology 55:62-70, 1981 251 Severinghaus JW, Feustel PJ: Cortical Ptco2 during and after middle cerebral artery occlusion. Br J Anes 53:309, 1981 252 Severinghaus JW: A combined transcutaneous Po2Pco2 electrode with electrochemical HCO3- stabilization. J Appl Physiol 51:1027-1032, 1981 253 Irsigler GB, Severinghaus JW: Respiratory regulation of cerebrospinal fluid and peripheral acid-base balance. In: The Kidney: Physiology and Pathology of Electrolyte Metabolism. Edited by DW Seldin, G Giebisch. Raven Press, 1985, pp 1459-1470 254 Severinghaus JW: Introduction to skin Pco2 measurement. In: Continuous Transcutaneous Blood Gas Monitoring. Edited by Huch R, Huch A. Marcel De Publisher, New York, 1983 255 Wilson D, Severinghaus JW, Maibach H: Newborn infant and adult transcutaneous Po2 resistance: A comparison. Arch Dermatol Res 271:119-125, 1981 256a Severinghaus JW: Regulation of Respiration and CSF Acid-Base Balance. In: Oxygen Transport to Human Tissues, J.A.Loeppke and M.L.Riedsel, editors, New York, Elsevier, 1982:231-241. 257 Severinghaus JW: Transcutaneous Blood Gas Analysis. Respir Care 27:152-159, 1982 258 Vurek GG, Peterson JI, Goldstein SR, Severinghaus JW: Fiber Optic Pco2 probe. Fed Proc 41:1484, 1982 259a Feustel PJ, Stafford MJ, Allen J, Severinghaus JW: Central chemoreceptor blood flow estimated by hydrogen clearance. Physiologist 24:115, 1981 (Abstract) 259b Feustel PJ, Ingvar MC, Severinghaus JW: Cerebral oxygen availability and blood flow during middle cerebral artery occlusion. Stroke 12:858-863, 1981 260 Hickey RF, Severinghaus JW: Regulation of Breathing: Drug Effects. In: Regulation of Breathing, Part II. Edited by Hornbein TF. New York, Marcel Dekker Publisher, 1981, pp 1251-1312 261 Hazinski TA, Severinghaus JW, Marin M, Tooley WH: Estimation of the Steady-State Ventilatory Response to Carbon Dioxide in Newborn Infants Using Skin Surface Electrodes. In: Continuous Transcutaneous Blood Gas Monitoring. Edited by Huch R, Huch A. Marcel Dekker Publisher, New York, 1983, pp 431-439 262 Severinghaus JW: Resistance of Skin Oxygen Diffusion: Methods. In: Neonatal Skin: Structure and Function. Edited by Maibach, Boisits. New York, Marcel Dekker Publisher, 1982, pp 131-136 263 Versmold HT, Severinghaus JW: Comparative Skin Barrier Function: Oxygen Diffusion. In: Neonatal Skin: Structure and Function. Edited by Maibach, Boisits. New York, Marcel Dekker Publisher, 1982, pp 115-120 264 Wilson DR, Maibach HI, Severinghaus JW: Variability in Skin Oxygen Diffusion Resistance Measurement. In: Neonatal Skin: Structure and Function. Edited by Maibach, Boisits. New York, Marcel Dekker Publisher, 1982, pp 121-130 265 Feustel PJ, Vurek GG, Severinghaus JW: Medullary respiratory chemoreceptor blood flow and Pco2 . In: Modelling and Control of Breathing. Edited by Whipp BJ, Wiberg DM. New York, Elsevier Science Publ Co, 1983, pp 29-36. 266 Kagawa S, Stafford MJ, Waggener TB, Severinghaus JW: No effect of naloxone on hypoxia-induced ventilatory depression in adults. J Appl Physiol 52:1030-1034, 1982 267 Levy R, Feustel PJ, Severinghaus JW, Hosobuchi Y: Effect of naloxone on neurologic deficit and cortical blood flow during focal cerebral ischemia in cats. Life Science 31:2205-2208, 1982 268 Severinghaus JW, Vanhoutte PM: Chairmen's Comments: New Trends in the Clinical Diagnosis of Brain Hypoxic Conditions. J of Cerebral Blood Flow and Metabolism, Vol. 2, Suppl 1, 1982 269 Hazinski TA, Severinghaus JW: Transcutaneous analysis of arterial Pco2 . Med Instr, 16:150-153, 1982 270 Severinghaus JW: Transcutaneous monitoring of arterial Pco2. In: Respiratory Monitoring in Intensive Care. Edited by Spence AA. Edinburgh, London, Churchill Livingstone Publisher, 1982, pp 85-91 271 Cahalan MK, Johnson BH, Eger EI, Sheiner LB, Richardson CA, Varner JK, Severinghaus JW: A noninvasive in vivo method of assessing the kinetics of halothane metabolism in humans. Anesthesiology, 57:298-302, 1982 272 Severinghaus JW: Interpreting Acid-Base Balance (Letters). Respiratory Care, 27:1414-1415, 1982 273 Kagawa S, Severinghaus JW: Trial manufacture of implantable pH-PCO2 electrode. Jpn J of Anesth, Vol 11, Suppl, 1982 274 Stafford MJ, Feustel PJ, Severinghaus JW: Scanning electron microscopy of nonuniform pulmonary arterial vasoconstriction in hypoxic rats. In: Hypoxia, Exercise, and Altitude. JR Sutton, CS Houston, NL Jones, eds. New York, Alan Liss, 1983, p. 475 (Abstract) 275 Stafford MJ, Feustel PH, Severinghaus JW. Pco2 difference between arterial blood and ventral medullary surface chemoreceptors. Physiologist 26: A38, 1983 (Abstract) 276 Severinghaus JW, Hoffman JIE: Transcutaneous Pco2 Statistics. In: Continuous Transcutaneous Blood Gas Monitoring. Edited by Huch R, Huch A. Marcel Dekker Publisher, New York, 1983, pp. 241-242 277 Levy RM, Feustel P, Severinghaus JW, Hosobuchi Y: Focal cerebral ischemia in the cat: Effect of naloxone on cortical blood flow and neurological deficit following middle cerebral artery occlusion. J Cerebral Blood Flow and Metabolism, 3:S365, Suppl 1, 1983 (Abstract) 278a Irsigler GB, Stafford MJ, Severinghaus JW: CO2 response lines by steady state and rebreathing techniques in metabolic acidosis and alkalosis, and their relation to estimated medullary chemoreceptor pH. Am Rev Respir Dis 129: A253, 1984 (Abstract) 278b Severinghaus JW: Viva Pascal but Kilo Newton? Anesthesiol 59: 486, 1983. 279 Feustel PJ, Stafford MJ, Allen JS, Severinghaus JW: Ventrolateral medullary surface blood flow determined by hydrogen clearance. J Appl Physiol, 56:150-154, 1984 280 Hazinski TA, Severinghaus JW, Marin MS, Tooley WH: Estimation of Ventilatory Response to Carbon Dioxide in Newborn Infants using Skin Surface Blood Gas Electrodes. J Pedi 105:389-393, 1984 281 Vurek GG, Feustel PJ, Severinghaus JW: A fiber optic PCO2 sensor. Ann Biomed Eng 11:499-510, 1984 282 Palmisano B, Severinghaus JW: Clinical accuracy of a combined transcutaneous Po2 -Pco2 electrode. J Crit Care Med 12:276, 1984 283 Gonzalez-Mendez R, Litt L, Weinstein PR, James TL, Murphy-Boesch J, Hamilton WK, Severinghaus J: An in vivo 31P NMR study of cerebral hypoxia and ischemia in anesthetized adult rats. Anesthesiology 61(3A):A318, 1984 (Abstract) 284 Litt L, Gonzalez-Mendez R, Severinghaus JW, Shuleshko J, Hamilton WK, Murphy-Boesch J, Richards T, James TL: An in vivo study of the effects of halothane on cerebral high energy phosphates during hypercarbia. Anesthesiology Rev 12(5):26-27, 1985 285 Rupp S, Severinghaus JW: Hypothermia. In: Anesthesia. 2nd ed. Edited by Miller RD. New York, Churchill-Livingstone, 1985 286 Astrup P, Severinghaus JW: Blodgassernes, syrernes og basernes historie. Copenhagen, Munksgaard, 1985, 316 pp. 287 Severinghaus JW, Astrup PB: Eight essays. The history of blood gas analysis. I. The development of electrochemistry. J Clin Monitor 1:180-192, 1985 288 Severinghaus JW, Astrup PB: The history of blood gas analysis. Eight essays. II. The measurement of pH. J Clin Monitor 1:259-277, 1985 289 Litt L, Gonzalez-Mendez R, Severinghaus JW, Hamilton WK, Shuleshko J, Murphy-Boesch J, James TL. Cerebral intracellular changes during supercarbia: An in vivo 31P nuclear magnetic resonance study in rats. J Cerebral Blood Flow Metab 5:537-544, 1985 290 Levy RM, Feustel PJ, Mills C, Hosobuchi Y, Severinghaus JW: Parallel studies of magnetic resonance imaging (MRI) and cortical blood flow in acute experimental cerebral ischemia. Magn Reson Med 1:279280, 1985 (Abstract) (Proceedings) 291 Litt L, Gonzalez-Mendez R, Severinghaus JW, Shuleshko J, Murphy-Boesch J, Hamilton WK, James TL: A 31P NMR study in rats of cerebral intracellular changes during supercarbia. Mag Reson Med 1:281-282, 1985 (Abstract) 292 Litt L, Gonzalez-Mendez R, Severinghaus JW, Shuleshko J, Murphy-Boesch J, Richard T, Hamilton WK, James TL: Halothane prevents a decrease in cerebral intracellular ADP during hypercarbia. Proceedings of the Fourth Annual Meeting of the Society of Magnetic Resonance in Medicine 1:283-284, 1985 (Abstract) 293 Severinghaus JW: Monitoring anesthetic and respiratory gases. In: Monitoring in Anesthesia and Critical Care Medicine. Edited by Blitt CD. Churchill Livingstone, New York, 1985, 265 pp. 294 Astrup P, Severinghaus JW: The History of Blood Gases, Acids and Bases. Copenhagen, Munksgaard, 1986, 332 pp. 295 Severinghaus JW, Astrup PB: The history of blood gas analysis. Eight essays. III. The history of the measurement of blood carbon dioxide tension. J Clin Monitor 2:60-73, 1986 296 Litt L, Gonzalez-Mendez R, Severinghaus JW, Hamilton WK, Rampil IJ, Shuleshko J, Murphy-Boesch J, James TL: Cerebral intracellular ADP concentrations during hypercarbia: An in vivo 31P NMR study in rats. J Cerebral Blood Flow Metab 6:389-392, 1986 297 Litt L, Gonzalez-Mendez R, Weinstein PR, Severinghaus JW, Hamilton WK, Shuleshko J, MurphyBoesch J, James TL: An in vivo 31P NMR study of cerebral hypoxic hypoxia in rats. Magnetic Res Med 3:619-625, 1986 298 Severinghaus JW, Astrup PB: The history of blood gas analysis. Eight essays. IV. Leland Clark's Oxygen Electrode. J Clin Monitor 2:125-139, 1986 299 Severinghaus JW, Astrup PB: The history of blood gas analysis. Eight essays. V. Oxygen, Part II. J Clin Monitor 2:174-189, 1986 300 Severinghaus, JW: Historical Development of Oxygenation Monitoring. In: Pulse Oximetry. Payne JP, Severinghaus JW, eds: Berlin: Springer, 1986, p1-18. 301 Payne JP, Severinghaus JW, eds: Pulse Oximetry. Berlin: Springer, 1986, 197 pp. 302 Litt L, Gonzalez-Mendez R, James TL, Chew W, Moseley M, Mills P, Sessler DI, Severinghaus JW, Hamilton WK: An in vivo 19F NMR study at 5.6 Tesla of halothane uptake and elimination in anesthetized rats. Anesth Analg 66:S105, 1986 (Abstract) 303 Severinghaus JW, Young WG: A gas-mixer for computer calibration of an anesthetic mass spectrometer. J Clin Monitor 2:223-229, 1986 304 Severinghaus JW, Astrup PB: The history of blood gas analysis. Eight essays. VI. The history of oximetry. J Clin Monitor 2:270-288, 1986 305 Naifeh KH, Severinghaus JW, Kamiya J: Effect of aging on sleep-related changes in respiratory variables. Sleep, 10 (2):160-171, 1986 306 Severinghaus JW: Hypocapnia on ventral medullary blood flow and pH during hypoxia. J Appl Physiol 62:850, 1987 (letter) 307 Severinghaus JW, Honda, Y: The history of blood gas analysis. Eight essays. VII. Pulse oximetry. J Clin Monitor, 3:135-138, 1987 308 Severinghaus JW, Naifeh, KH: Accuracy of response of six pulse oximeters to profound brief steady hypoxia. Anesthesiology 67:551-558, 1987 309 Litt L, Gonzalez-Mendez R, James T, Chew W, Moseley M, Mills P, Sessler D, Severinghaus JW, Hamilton WK: An in vivo 19F NMR study at 5.6 Tesla of halothane uptake and elimination in anesthetized rats. Anesth Analg 66(Suppl):S105, 1987 (Abstract) 310 Litt L, Gonzalez-Mendez R, James TL, Sessler DI, Mills P, Chew W, Moseley M, Pereira B, Severinghaus JW, Hamilton WK: An in vivo study of halothane uptake and elimination in the rat brain with fluorine nuclear magnetic resonance spectroscopy. Anesth Analg 66(Suppl):S105, 1987 311 Bickler PE, Severinghaus JW, Litt L: Acetazolamideinduced carbonic acidosis improves brain cortex oxygenation during hypoxia. Annual Association of University Anesthetists, Portland, Oregon, May 1987 (Abstract) 312 Bickler PE, Litt L, Banville DL, Severinghaus JW: In vivo 19F/1H NMR measurements of effects of acetazolamide on brain acid-base balance in rabbits. Society of Magnetic Resonance Sixth Annual Meeting, August 17-21, 1987 (Abstract) 313 Naifeh KH, Severinghaus JW: Validation of a maskless CO2 response test for sleep and infant studies. J Appl Physiol, 64:391-396, 1988 314 Severinghaus JW, Naifeh KH: Responses of four pulse oximeters to profound hypoxia. Monitoring workshop: Palmas Del Mar, Puerto Rico, Jan 14-16, 1987 (Abstract) 315 Severinghaus JW: Continuous monitoring of alveolar and inspiratory concentrations of anesthetic and respiratory gases is safe, simple, and cost effective. J Clin Monitor 3:123, 1987 316 deleted 317 Bickler P, Severinghaus JW: Effects of acetazolamide (AZ) on cerebral ECF acid-base balance. Fifth International Hypoxia Symposium, Chateau Lake Louise, Alberta, Canada, Feb 10-14, 1987 (Abstract) 318 Severinghaus JW: Profound brief hypoxic steps: Method and tolerance. Fifth International Hypoxia Symposium, Chateau Lake Louise, Alberta, Canada, Feb 10-14, 1987 (Abstract) 319 Severinghaus JW: History, status and future of pulse oximetry. Adv Exp Med Biol 220:3-8, 1987 320 Severinghaus JW, Astrup PB: History of Blood Gas Analysis. International Anesthesiology Clinics, Winter 1987, Volume 25, No. 4. Boston, Little Brown, 1987, pp1224 320b Severinghaus JW, Honda Y. Pulse Oximetry. In History of Blood Gas Analysis. International Anesthesiology Clinics, Winter 1987, Volume 25, No. 4. Boston, Little Brown, 205-214 321 Bickler PE, Litt L, Severinghaus JW: Effects of acetazolamide on cerebrocortical NADH and blood volume during hypoxia. Physiologist 30:165, 1987 322 Severinghaus JW: Can the Raman Scattering Analyzer compete with mass spectrometers? Wellcome Trends in Anesthesiology 5:11, 1987 323 Bissonnette B, Bickler PE, Gregory GA, Severinghaus JW: Does increased FIO2 alter NADH redox state and protect brain cells from ICP changes in rabbits? International Anesthesia Research Society, 1987 324 Lassen NA, Severinghaus JW: Acute mountain sickness and acetazolamide. In: Hypoxia and Cold. Edited by Sutton JR, Houston CS, Coates G. New York, Praeger, 1987, pp. 493-504 325 Severinghaus JW: Oximetría de pulso: Una revolución en anestesiología. Rev Esp Anestesiol Reanim 35:119120, 1988 326 Bickler PE, Litt L, Banville DL, Severinghaus JW: Effects of acetazolamide on cerebral acid-base balance. J Appl Physiol 65:422-427,1988 327 Bickler PE, Litt L, Severinghaus JW: Effects of acetazolamide on cerebrocortical NADH and blood volume. J Appl Physiol 65:428-433, 1988 328 Jaffe GJ, Irvine AR, Wood IS, Severinghaus JW, Pino GR, Haugen C: Retinal phototoxicity from the operating microscope: The role of inspired oxygen. Ophthalmology 95:1130-1141, 1988 329 Bissonnette B, Bickler PE, Gregory GA, Severinghaus JW: Does increased FIO2 alter NADH redox state and protect brain cells from ICP changes in rabbits? Anesthesiology 69: 3A, 1988 330 Severinghaus JW: Zen and the art of brain maintenance. Special Symposium Issue on Clinical Death. Crit Care Med 16:1019-1021, 1988 331 Stephenson H, Safar P, Severinghaus JW, et al.: Treatment potentials for reversing clinical death. Crit Care Med 16:1034-1042, 1988 332 Moossy J, Safar P, Severinghaus JW, et al.: Pathophysiologic limits to the reversibility of clinical death. Crit Care Med 16:1022-1033, 1988 333 Bickler PE, Severinghaus JW: Transcellular distributions of protons and deuterons in Paramecium suggest a neutral flux model for acid-base balance. FASEB Journal 2:A948, 1988 (Abstract) 334 Honda Y, Hashizume I, Kimura H, Severinghaus JW: Bilateral carotid body resection in man enhances hypoxic tachycardia. Jap J Physiol 38: 917-928, 1988 335 Koh SO, Severinghaus JW: Effect of halothane on hypoxic and hypercapnic ventilatory responses in goats. Anesthesiology 71:3A, A1083, 1989 (Abstract) 336 Koh SO, Severinghaus JW: Effect of halothane on hypoxic and hypercapnic ventilatory responses in goats. International Symposium on Control of Breathing and Dyspnea, Sendai, Japan, 1989 (Abstract) 337 deleted (Sessler, never publ) 338 Litt L, Cohen Y, Chang LH, Kim F, Germano I, Davis RL, James TL, and Severinghaus JW: Stability of rat brain intracellular pH, lactate, and 31P metabolites during severe, prolonged hypercapnia. 1989 (Abstract) 339 Severinghaus JW: Oximetry I: Nomenclature, history, accuracy, and uses. In: Anesthesia and the Lung. Stanley TH, Sperry RJ, eds. Dordrecht, Kluwer Academic Publishers, 1989, pp. 93-97 340 Severinghaus JW: Oximetry II: Limitations and effects on other monitors. In: Anesthesia and the Lung. Stanley TH, Sperry RJ, eds. Dordrecht, Kluwer Academic Publishers, 1989, pp. 127-131 341 Honda Y, Nishibayashi Y, Hashizume I, Kimura H, Severinghaus JW: Enhanced heart rate elevation during hypoxic breath holding in patients with carotid body resection. XXXI International Congress of Physiological Sciences, 1989 (Abstract) 342 Severinghaus JW, Naifeh KH, Koh SO: Errors during profound hypoxia in 14 pulse oximeters. J Clin Monitor 5:72-81, 1989 343 Naifeh KH, Severinghaus JW, Kamiya J, Krafft M: Effect of aging on estimates of hypercapnic ventilatory response during sleep. J Appl Physiol 66:1956-1964, 1989 344 Cohen Y, Chang L-H, Litt L, Kim F, Severinghaus JW, Weinstein PR, Davis RL, Germano I, James TL: Stability of brain intracellular lactate and 31P metabolite levels at reduced intracellular pH during prolonged hypercapnia in rats. J Cerebral Blood Flow Metab 10:277-284, 1990 345 Severinghaus JW: Water vapor calibration errors in some capnometers: Respiratory conventions misunderstood by manufacturers? Anesthesiology 70:996-998, 1989 346 Severinghaus JW: Carotid body resection for COPD? Chest 95:1128-1129, 1989 from 347 Severinghaus JW: Determination of PO2 saturation. J Appl Physiol 67:902, 1989 (Reply to letter from Roger K. Ellis) 348 Bickler PE, Koh SO, Severinghaus JW: Effects of hypoxia and hypocapnia on brain redox balance in ducks. Am J Physiol 257:Ra132-135, 1989 349 Palmisano BW, Severinghaus JW: Transcutaneous Pco2 and Po2 : A multicenter study of accuracy. J Clin Monitor 6:189-195, 1990 350 Severinghaus JW, Koh SO: Effect of anemia on pulse oximeter accuracy at low saturation. J Clin Monitor 6:8588, 1990 351 Severinghaus JW, Spellman, MJ Jr: Pulse oximeter failure thresholds in hypotension and vasoconstriction. Anesthesiology 73:532-537, 1990 352 Koh SO, Severinghaus JW: Effect of halothane on hypoxic and hypercapnic ventilatory responses of goats. Br J Anaesth 65: 713-717, 1990 353 Wimberley PD, Siggaard-Andersen O, Fogh-Andersen N, Zijlstra WG, Severinghaus JW: Hemoglobin oxygen saturation and related quantities: Definitions, symbols, and clinical use. Scand J Clin Lab Invest, 50:455-459, 1990 354 Severinghaus JW: Anesthesia and the regulation of breathing. Rev Espan Anestesiol Reanim, 37: 179-184, 1990 355 Severinghaus JW: "Precision." Gorback-Letter to the Editor. J Clin Monitor 6:159, 1990 356 Honda Y, Hashizume I, Kimura H, Severinghaus JW: Hypoxia >25 years after carotid body resection causes more tachycardia although less hyperventilation than in controls. In: Respiratory Control. Edited by Swanson GD, Grodins FS, and Hughson RL. Plenum, 1989, pp. 201-205 357 Severinghaus JW: What's new with CO2 ? Acta Anaesthesiol Scand 34 (Suppl 94): 13-17, 1990 358 Severinghaus JW, Xu F, Spellman MJ Jr: Benzocaine and methemoglobin: Recommended FDA action. Letter to the Editor. Anesthesiology 74: 385-386, 1991 359 Severinghaus JW: Acetazolamide and respiration: Theory and uses. Intensive Crit Care Digest 9: 32-34, 1990 360 Sato M, Severinghaus JW, Basbaum AI: Medullary CO2 chemoreceptor neuron identification by c-fos immunocytochemistry. FASEB Journal 5: A1120, 1991 361 Severinghaus JW: Acid-base balance controversy. J Clin Monitor, 7: 274-279, 1991 362 Xu F, Severinghaus JW, Spellman MJ Jr, Sato M: Hypoxia uniquely acidifies medullary ventral surface ECF. FASEB Journal 5: 4342, 1991 363 Severinghaus JW, Sato M, Powell F, Jensen JB, Sperling B, Lassen N. Altitude acclimatization slowly augments hypoxic responses of ventilation and cerebral circulation. Clin Res 39: 387A, 1991 364 Xu F, Spellman MJ Jr, Sato M, Baumgartner JE, Ciricillo SF, Severinghaus JW: Anomalous hypoxic acidification of medullary ventral surface. J Appl Physiol 71: 2211-2217, 1991 365 Bissonnette B, Bickler PE, Gregory GA, Severinghaus JW: Effects of intracranial pressure on brain redox balance in rabbits. Can J Anaesth 38: 654-659, 1991 366 Xu Y, Cohen Y, Litt L, Chang L-H, Severinghaus JW, James TL: Tolerance of low cerebral intracellular pH during severe hypercapnia and adequate oxygenation: An in vivo NMR study in a hyperbaric chamber. Stroke 22(10): 1303-1308, 1991 367 Severinghaus, JW: Oximetry: Uses and Limitations. In: American Society of Anesthesiology ASA Refresher Courses in Anesthesiology, 19: 139-152, 1991 368 Severinghaus JW: Response to Watney equation. Letter to the Editor. J Appl Physiol 72: 399-400, 1992 369 Severinghaus JW: Respiratory control related to altitude and anesthesia. In: Anesthesia and the Lung, 1992, Volume 25, Stanley, TH, and Sperry, RJ, eds. Dordrecht, Kluwer Academic Publishers, 1992, pp. 101115 370 Severinghaus, J. W., P. E. Bickler, M. W. Eldridge: Pressure-dependent pulmonary shunting during HAPE: Theory. Physiologist 35: 48.28, 1992. 371 Eldridge M.W., J.W.Severinghaus, P.E.Bickler: Pulmonary gas exchange impairment in ultramarathoners following a 100 mile race at altitude. Physiologist 35: 48.25, 1992. 372 Severinghaus JW, Kelleher JF: Recent developments in pulse oximetry. Anesthesiology, 76: 1018-1038, 1992 373 Severinghaus JW: More RIpH. Letter to the Editor. JAMA, 267(15): 2035-2036, April 15, 1992 374 Sato M, Severinghaus JW, Powell FL, Xu F, Spellman MJ Jr: Augmented hypoxic ventilatory response in man at altitude. J Appl Physiol 73: 101-107, 1992 375 Sato M, Severinghaus JW, Basbaum AI: Medullary CO2 chemoreceptor neuron identification by c-fos immunocytochemistry. J Appl Physiol 73:96-100, 1992 376a Sato M, Severinghaus JW, Bickler PE, Spellman MJ Jr: Hypoxic ventilatory response rises over 2 weeks at 3810M altitude. Clin Res 40: 66A, 1992. 376b Sato M, Severinghaus JW, Bickler PE, Spellman MJ Jr: Hypoxic ventilatory response rises over 2 weeks at 3810M altitude. Abstracts of World Cong Anaesth, The Hague, 12-19 June 1992, P225 377 Severinghaus JW, Sato M, Bickler PE, Spellman MJ: Differential hypoxic response during hypoxic ventilatory depression. Clin Res 40: 66A, 1992. 378 Severinghaus JW, Eldridge MW, Spellman MJ Jr: Effect of Po2 and exercise on pressure-shunts in mild high altitude pulmonary edema. Abstracts of World Cong Anaesth, The Hague, 12-19 June 1992, P226 379 Podolsky A, Eldridge M, Knight D, Poole D, Richardson R, Johnson D, Johnson C, Bickler P, Wagner P, Severinghaus J: Pulmonary gas exchange after two days at high altitude. Faseb J 9:21A;119, 1993. 380 Eldridge MW, Severinghaus JW, Bickler PE, Wood SC: Effect of maximal exercise at moderate altitude on post exercise gas exchange in sojourners and altitude natives. Abs, 8th Int Hypox Symp, Lake Louise, CA Feb 9-13, 1993 381 Severinghaus, JW: Zero cytochrome Po2 , anaerobic threshold and lactate paradox: Insights from polarography. Abs, 8th Int Hypox Symp, Lake Louise, CA Feb 9-13, 1993 382 Feiner JR, Bickler PE, Severinghaus JW: A poor hypoxic ventilatory response predicts greater oxyhemoglobin desaturation during breath-holding. Abs, 8th Int Hypox Symp, Lake Louise, CA Feb 9-13, 1993 383 Severinghaus JW: Siggaard-Andersen and the Great TransAtlantic Acid Base Debate. Acta Physiol Scand 53, S214: 99-104, 10 Dec 1992. 384 Severinghaus JW: History and recent developments in pulse oximetry. Acta Physiol Scand 53, S214: 105-112, 10 Dec 1992. 385 Xu F, Sato M, Spellman MJ Jr, Mitchell RA, Severinghaus JW: Topography of cat medullary ventral surface hypoxic acidification. J Appl Physiol 73: 26312637, 1992. 386 Steffey EP, Woliner MJ, Young WG, Severinghaus JW: Two year's experience with a multi-station, multianesthetic and respiratory gas analysis system (MARGAS). J Veterinary Anesthesia, 1993 Proc 4th Int Congr p83-85. 387 Eriksson LI, Sato M, Severinghaus JW: Effect of a vecuronium-induced partial neuromuscular block on hypoxic ventilatory response. Anesthesiol 78: 693-699, 1993. 388 Severinghaus JW: Claude Bernard's Lectures on Anesthetics and Asphyxia Translated by B. Raymond Fink, MD. Book Rev, J Clin Mon 9:121,1993 389 Severinghaus JW: Pulse oximetry. In: Computing and monitoring in anesthesia and intensive care, Ikeda K et al, eds, Springer-Verlag, Tokyo, 1992, pp391-403 390 Severinghaus JW: Invited editorial on "Widespread sites of brain stem ventilatory chemoreceptors". J Appl Physiol 75:3-4, 1993. 391 Severinghaus JW: Where is the leak in HAPE? Twentieth Anniversary Souvenir, Himalayan Rescue Association Nepal. p25-31, Dec 3, 1993 392 Johnson DH, MW Eldridge, A Podolsky, RS Richardson, PD Wagner, JW Severinghaus: The role of immunological mediators in the development of highaltitude pulmonary edema. Clin Res 42, No 1: 59A (Abstract), 1994. 393 Sato M, JW Severinghaus, PE Bickler: Time course of augmentation and depression of hypoxic ventilatory responses at altitude. J Appl Physiol 77: 313-316, 1994. 394 Severinghaus JW: Exercise O2 transport model assuming zero cytochrome Po2 at VO2 max. J Appl Physiol 77: 671-678, 1994. 395 Severinghaus, JW: Nomenclature of oxygen saturation. Oxygen Transport to Tissue XV, Edited by P. Vaupel et al., Plenum Press, New York, 1994, pp921-923. (Adv in Exp Med Biol 345). 396 Severinghaus JW: Is zero cytochrome Po2 the limit of muscle work? Eur J Appl Physiol & Occup Physiol 69(3) suppl: S12, 1994 (ISOTT, Istanbul 94) 397 Severinghaus JW Hypothetical roles of angiogenesis, osmotic swelling and ischemia in high altitude cerebral edema. J. Appl. Physiol. 79:375-379, 1995 398 Jensen JB, Sperling B, Severinghaus JW, Lassen N: Augmented hypoxic cerebral vasodilation in man during five days of acclimatization to 3800 meters of altitude. J Appl Physiol 80: 1214-1218, 1996. 399 Severinghaus, JW. Discrepancy between evidence and theory of myoglobin SO2 in work. Proceedings, ISOTT XVII, Sept 94, Adv Exp Med Biol 388, p237-240 400 Severinghaus, JW. Cerebral Circulation at Altitude. in High Altitude, edited by T.F. Hornbein and R. Schoene, Vol 161, Lung Biology in Health and Disease, edited by C. Lenfant, Marcel Dekker, New York, 2001, 343-375 401 Severinghaus, JW. Seeking bottom lines in the deeper oxygen picture. Acta Anaesth Scand 39: Suppl 105, 4751, 1995 402 Severinghaus, JW. The status of monitoring in neuroanesthesia. Acta Anaesth Scand 39: Suppl 105, 5256, 1995 403 Feiner, JR, Bickler PE, Severinghaus, JW. Hypoxic ventilatory response predicts the extent of maximal breath-holds in man. Resp Physiol 100: 213-222, 1995 404 Severinghaus, JW. Hypothesis: Angiogenesis cytokines in high altitude cerebral oedema. Acta Anaesth Scand 39: Suppl 107, 177-178, 1995 405 Podolsky, A, Eldridge MW, Richardson RS, Knight DR, Johnson EC, Hopkins SR, Johnson DH, Michimata H, Grassi B, Feiner J, Sadi Kurdak S, Bickler PE, Severinghaus JW, Wagner PD . Exercise-induced VA/Q inequality in subjects with prior high altitude pulmonary edema. J Appl Physiol 81:922-932, 1996 406. Eldridge MW, Podolsky A, Richardson RS, Johnson DH, Knight DR, Johnson EC, Hopkins SR, Michimata H, Grassi B, Feiner J, Sadi Kurdak S, Bickler PE , Wagner PD, Severinghaus JW. Pulmonary hemodynamic responses to hypoxia and exercise in individuals susceptible to high altitude pulmonary edema. J Appl Physiol 81:911-921, 1996. 407. Severinghaus JW: Oxygen transport in blood and to mitochondria. In: Exercise and circulation in health and disease. Saltin B, Boushel R, Secher N, Mitchell J, editors. Champaign IL, Human Kinetics, 1999, p169-174 408. Jerome, E. Heidi and J.W.Severinghaus. High altitude pulmonary edema. (Editorial). NEJM 1996, (Mar 7) 334: 662-663. 409. Astrup, P and J. W. Severinghaus. Blood Gas Transport and Analysis. in Respiratory Physiology: People and Ideas edited by John B. West. New York, Oxford Univ Press, 1996: pp75-107 410. Severinghaus JW: Hypoxic ventilatory depression may be due to central chemoreceptor cell hyperpolarization. p257-260 in Modeling and control of ventilation, eds Semple SJG, Adams L and Whipp B. Adv Exp Med Biol 393 New York, Plenum, 1995. 411. Severinghaus JW: Pulse oximetry. In: Computing and monitoring in anesthesia and intensive care. Edited by Ikeda K, Doe M, Kazama T, Sato K and Oyama T. Tokyo, Springer Verlag, 1992, p391-403. 412. Severinghaus JW: Hypoxic ventilatory depression and ventral medullary acidosis. In: Ventral brainstem mechanisms and control of respiration and blood pressure edited by Trouth CO, Millis RM, Kiwull-Schöne HF and Schläfke ME. Vol 82 in "Lung Biology in Health and Disease", exec editor Lenfant, C. New York, M Dekker, 1995, pp151-155. 413 Xu FP, JW Severinghaus: Rat brain VEGF expression in alveolar hypoxia: possible role in high-altitude cerebral edema. J. Appl Physiol. 85: 53-57, 1998. 414 Xu FP, JW Severinghaus: Expression and response to hypoxia of vascular endothelial growth factor (VEGF) in rat and rabbit tissues. In: Oxygen Transport to Tissue XX, A. G. Hudetz and D.F.Bruley, editors, Plenum Press, New York, 1998, P311-317. 415 . Severinghaus JW. Uses of high altitude for studies of effects of hypoxia. In: Oxygen Transport to Tissue XX, ed Hudetz and Bruley, Plenum, Advances in Experimental Medicine and Biology, 1998, 454:17-28. 416. Schlichtig R, Grogono AW, Severinghaus JW: Current status of acid-base quantitation in physiology and medicine Anesthesiology Clinics of North America, 1998, 16(1): 211-234 417. Severinghaus JW, Astrup P, Murray J. Blood gas analysis and critical care medicine. Am J Respir Crit Care Med 157: S114-S122, 1998 418. Severinghaus, JW: Enigmas and Insights in Oxybiology, In: Physiology and Pharmacology of Cardiorespiratory control . Dahan A ,Teppema L van Beek JHGM, editors. Kluwer Academic, Dordrecht, 1998, pp310. 419. Schlichtig R, Grogono AW, Severinghaus JW. and Standard Base Excess Human PaCO2 Compensation for Acid-Base Imbalance. Crit Care Med 1998;26: 1173-1179 420. Severinghaus, JW. Tribute to Niels Lassen. Clinical Physiology 17(5):541-2, 1997. 421. Severinghaus, JW. Endotoxin hyperventilation mechanisms [editorial; comment]. Critical Care Medicine, 1998 Sep, 26(9):1481-2. 422. Severinghaus, JW. Incapacitating ventilatory drive at high altitude. ISMM News 8, No 1, Winter 1997-8: 12-13. 423. Severinghaus, JW. Altitude Hypoxia Effects on Brain. Acta Andina VI. No 2, 1997: 133-141. (2nd World Congress on high altitude medicine and physiology, Cuzco, Peru, Sept 24-27, 1996. 424. Severinghaus, JW. High altitude incapacitating dyspnea without HACE or HAPE. in Progress in Mountain Medicine and High Altitude Physiology, H Ohno, T Kobayashi, S Masuyama and M Nakashima, Eds, Japanese Soc. Mt. Med., Tokorozawa, Japan 1998: 386-7 425. Severinghaus, JW. Intrathecally, Caine may dis-Able. Rare problems with clinical use of lidocaine for spinal anesthesia. Acta Anaesth Scand 1998 ; 42 S113:3-7. 426. Severinghaus, JW, Astrup P. History of Blood Gas Analysis. in "Proceedings, The Fourth International Symposium on the History of Anesthesia", editted by J. Schulte am Esch and M. Goerig. Lubeck: DragerDruck, 1998; p591-596 427. Gregory, GA, Feiner, J, Severinghaus, JW: Tidal Volume, PaCO2 and Lung Injury. [editorial; comment] Critical Care Medicine, 1998; 26: 1632-3. 428,429. Severinghaus, JW. Letter to J Clin Mon re Soller, B.R. JCM 1996;12:387-395 (Use of IR to measure muscle pH). Answer 429 430. Severinghaus, JW. The current status of transcutaneous blood gas analysis and monitoring. Blood Gas News (Radiometer house organ) vol 7, No 2, 1998. pp4-9, 25,27. 431. Severinghaus, JW. Hans Loeschcke, Robert Mitchell and the medullary CO2 chemoreceptors: a brief historical review. Respiration Physiology 114 (1998) 17-24 432. Severinghaus, John W. Paradoxical relation of Chapter 69 in “Oxygen mitochondrial Po2 to Vo2. Transport to Tissue XXI”, editors: Eke, A. and Delpy, D. Adv Exp Med Biol 471; New York, Kluwer AcademicPlenum, 1999, pp. 595-604. 433. Severinghaus, J.W. Stumbling over a bias: How it really happened. Am J Respir Crit Care Med 161: 3-4, 2000. 434. Feiner J, Severinghaus JW: Regulation of Respiration, Chap 46 in “Foundations of Anesthesia: Basic and Clinical Sciences.” edited by Hemmings, H. and Hopkins, PM. London, Mosby- Harcourt, 2000, pp483-489. 435. Severinghaus, John W. What dreams may come with nitrous oxide. The History of Anaesthesia Society Proceedings 1999; 25:64-67 436. Severinghaus, John W. Priestley, the furious free thinker of the enlightenment, and Scheele, the taciturn apothecary of Uppsala. Acta Anaesthesiologica Scandanavica 46: 2-9, 2002. 436B: Lindahl, SGE. Phlogiston – Fire Air – Oxygen. The fascinating story of an 18th Century discovery. Acta Anaes Scand 2002: 46, 1 (editorial) 437. Severinghaus, John W. The Invention and Development of Blood Gas Apparatus. Anesthesiology 2002;97: 253-256 438. Severinghaus JW. Severinghaus electrode. In: Maltby JR (Ed.). Notable Names in Anaesthesia. London: Royal Society of Medicine Press Ltd., 2002:199-201. 439. Severinghaus, John W. Two Revolutions in Critical Care Medicine: Blood Gas and Oximetry. Focus Mul 20, Heft 1, 85-93 (2003) [Zeitschr für Wissenschaft, Forschung und Lehre an der Universität zu Lübeck] 440, Severinghaus, John W and W. Andrew Kofke. An Interview with John W. Severinghaus, M.D. AUA Update, fall, 2003. Kofke, W.A., editor, Anesthesia, U.Penna, 3400 Spruce St, Phila PA 19104. 441. Severinghaus, JW. Fire Air and Dephlogistication. Revisionisms of oxygen’s discovery. In Hypoxia, Through the Life Cycle, Edited by Roach RC, Wagner PD and Hackett PH. AdvExpMedBiol 543:7-19, 2003. Kluver Academic/Plenum, NY. 441b Hornbein, TF. A tribute to John Wendell Severinghaus. In Hypoxia, Through the Life Cycle, Edited by Roach RC, Wagner PD and Hackett PH. AdvExpMedBiol 543:1-6, 2003. Kluver Academic/Plenum, NY. 442. Jones, J.G. The Hypoxia Hilton: recollections of a visit, with a postscript by J W Severinghaus on mechanisms of acute mountain sickness. J Roy Soc Med 95, Dec 2002:606-608. 443.. Walby WF, Mansoor JK, Kajekar R, Morrissey BM, Yoneda KY, Juarez M, Eldridge MW, Severinghaus JW, Schelegle ES. Effect of L-Arginine supplementation on breath condensate VEGF, exhaled NO, plasma erythropoietin and subjective symptoms at 4383 m. VI world congress on mountain medicine and high altitude physiology, Xining, Qinghai, China Aug 2004. 444. Severinghaus JW. Memories of Yoshiyoki Honda, MD, PhD. Adv Exp Med Biol 2004, 551:23 Kluver Academic/Plenum, New York. 445. Severinghaus, JW. First electrodes for blood PO2 and PCO2 determination.In “Essays on APS Classic Papers “. J. Appl. Physiol. 2004;97:1599-1600. 446. Kagawa, S, Otani, N, Kamide, M, Gisiger, PA, Eberhard, P, Severinghaus, JW. Initial transcutaneous PCO2 overshoot with ear probe at 42oC. J. Clin Mon Comp 2005;18:343-345. 447. KAGAWA, Sohei, Chieko FUJIWARA,Tomoko OTAKE-OTANI,Shin KAGAYA, Masanori TAKINAMI,Yasumasa TANIFUJI,and John W.SEVERINGHAUS Assessment of the Hypercapnic Ventilatory Response Measured with the Transcutaneous and Inspired Partial Pressures of CO2 Sohei Jikeikai Med J 2005; 52:59-62 448. Kagawa, Sohei and Severinghaus, J.W. Errors in monitoring transcutaneous Pco2 on the ear. Critical Care Medicine. 33(10):2414-2415, October 2005. 449. Feiner J, Severinghaus JW: Regulation of Respiration, Chap 46 in “Foundations of Anesthesia: Basic Sciences for Clinical Practice.” edited by Hemmings, H. and Hopkins, PM., 2nd edition London, Mosby- Harcourt, 2005, pp563-571. 450. Bickler, PE, Feiner, JR, Severinghaus, JW. Effects of Skin Pigmentation on Pulse Oximeter Accuracy at Low Saturation. Anesthesiology. 102(4):715-719, April 2005. oxygenation* (Invited Editorial) Crit Care Med 2003; (Abstract). 31: 1870-1871 451. Severinghaus, J.W. CO2 Electrodes. In Encyclopedia 467. Severinghaus John W. Translating Basic Science of Medical Devices and Instrumentation. 2nd ed, Vol 2, to Clinical Care. Anesteziologie a intenzivní C-D. editor John G. Webster. 2006, Wiley Interscience, medicína. 2010; Vol? 70-76 John Wiley & Sons, Hoboken, NJ, pp 109-120. 468. Severinghaus JW. History of Respiratory 452. Severinghaus, J. W. Arterial Blood Gases. In Monitoring in Anesthesia. In “History of Encyclopedia of Respiratory Medicine. Editors: G. J. Anesthesia”, Eger EI, Saidman L and Westhorpe Laurent and S. D. Shapiro. 2006 Elsevier Ltd p144-150. R, to be published in book by Springer Verlag 453. Severinghaus, J.W. Can large volume N2O uptake alone explain the second gas effect? Br J Anaes 2006; 97(2):262-263 454. Severinghaus, John W. The Rahn-Otis Discovery of Hypoxic Ventilatory Decline. High Alt Med & Biol 2005;6:339-341 455. Severinghaus, John W. “A World on Fire”, Joe Jackson (book review). Physics Today 59(8) Aug. 2006: 51. 456. Severinghaus, John W. Mass Law Predicts Hyperbolic Hypoxic Ventilatory Response. In: Oxygen Transport to Tissue XXVII, edited by G. Cicco, D.F.Bruley, M .Ferrari and D.K. Harrison. Advances in Experimental Medicine and Biology 578 (Springer, New York, 2006) pp41-48. 457. Severinghaus, John W. History of Measuring O2 and CO2 Responses. Advances in Experimental Medicine and Biology. Eds: M.J. Poulin and R.J.A. Wilson. Springer Publishers, New York. 2007, 605:3-8 458. Severinghaus, John W. Takuo Aoyagi: Discovery of Pulse Oximetry. Anesth Analg. 2007, (Dec) 105(S):S1-4 459. Severinghaus, John W. A Rambling and Brief Autobiography. In Careers in Anesthesiology – Autobiographical Memoirs. Vol VIII, Caton D and McGoldrick K, eds, 2004, Wood Library-Museum of Anesthesiology, Park Ridge, IL, pp183-273. 460. Steinbach E, Severinghaus J W, Ainslie P, Poulin M. Isocapnic and poikilocapnic hypoxia ventilatory response consensus methods in humans. In Hypoxia and Exercise 2006: Eds Roach R, Wagnr P, Hackett P. Adv Exp Med Biol 588:336 (abs) 461. Severinghaus, John W. Gadgeteering for Health Care: The John W. Severinghaus Lecture on Translational Science. Anesthesiology. 110(4):721728, April 2009 462. Severinghaus John W. Sensitivity of cerebral blood flow to hypoxia and hypoxic hypocapnia in Ethiopian Highlanders. JHAMB 9(4)2008:1-2 463. Severinghaus, John W. Translating basic science to clinical care. Anesteziologie & intenzivni medicina 2010: 21(2):70-76. 464. Severinghaus J W Bassett and Other Memories. P&S Journal.10May2010 <http://juno.cumc.columbia.edu/psjournal/remembr ances/bassett-and-other-memories> 465. Severinghaus JW. Fire-air and dephlogistication: Revisionisms of oxygen’s discovery. In: Hypoxia: Through the Lifecycle, Chapter X. edited by R.C. Roach et al. Kluwer Academic/Plenum Publishers, New York, 2003. 466. Severinghaus J W Continuous positive airway pressure, shock therapy, and gastric mucosal