Public sector support and benefits for the investor Strong public sector support for the biotechnology industry is channeled through various public institutions. Law No. 26270 establishes a range of measures designed to foster the development of biotechnology through incentives related to workforce and expenditure on capital goods during the different phases of R&D and technology development. The Argentine government has also implemented different programs and instruments to facilitate and encourage basic research and technological development, making biotechnology one of the top priorities. The main financing programs available to investors in the area of biotechnology are FONARSEC (which fosters the association between public entities and private companies—with biotechnology as one of its priorities); FONTAR (which grants non-reimbursable funds, tax credits or direct loans to companies); and PILD (Work Placement Program for PhDs, which co-finances the wages of doctorate program graduates who join the private-sector workforce). Furthermore, the Bicentennial Financing Programs are a highly attractive instrument for productive investments, with financing for up to AR$ 8 million to be repaid in five years at a fixed annual rate of 9.9%. Discover the unbeatable investment opportunities Argentina’s biotechnology industry offers investors. The Undersecretariat for Investment Development and Trade Promotion is your strategic partner for investing in Argentina What the Undersecretariat can do for you: Provide specific information on business sectors and geographical locations in Argentina. Help identify specific investment opportunities in strategic sectors through the Productive Investment Opportunities Database (http://bapip.inversiones.gov.ar). Facilitate the investment process throughout all the stages of the project in a personalized and professional manner. Assist in building partnerships between international investors and local companies. CONTACT US: info@inversiones.gov.ar – www.inversiones.gov.ar/en BIOTECHNOLOGY IN ARGENTINA: INFORMATION SOURCES GOVERNMENT INSTITUTIONS Ministry of Science, Technology and Productive Innovation www.mincyt.gob.ar Ministry of Industry www.industria.gob.ar National Institute for Industrial Technology (INTI) www.inti.gob.ar/biotecnologia National Institute for Agricultural Technology (INTA) www.inta.gob.ar Buenos Aires Biomedicine Research Institute www.ibioba-conicet.gob.ar Scientific and Technological Park of the Littoral Center www.ptlc.org.ar Rosario Technological Pole www.polotecnologico.net Biotechnology Research Institute, National University of San Martín www.iib.unsam.edu.ar Leloir Institute Foundation www.leloir.org.ar Experimental Biology and Medicine Institute www.ibyme.org.ar National University of Quilmes www.unq.edu.ar PROMOTION CHAMBERS AND INSTITUTIONS Argentine Chamber of Biotechnology www.cabiotec.com.ar Argentine Council for Biotechnology Information and Development (ArgenBio) www.argenbio.org Association of Argentine Seedgrowers www.asa.org.ar Argentine Biotechnology Forum www.foarbi.org.ar Argentine Chamber of Biotechnology for Artificial Reproduction and Insemination (CABIA) www.cabia.org.ar RedBio (FAO Technical Cooperation Network) www.fundacionredbio.org Biotechnology in Argentina Applied science for the world ARGENTINA: FORMULATING INNOVATIVE SOLUTIONS Why buy and invest in biotechnology in Argentina? WORLD-CLASS SCIENTISTS Argentina: scientific tradition, diversity and innovation in biotechnology Argentina’s scientific professionals are renowned for their outstanding skills and their capacity for innovation rooted in a long tradition of scientific excellence. The qualities they embody endow the country’s biotechnology sector with significant advantages for development. A number of educational institutions recognized worldwide offer programs in biotechnology at both post-graduate and post-doctoral levels. The country has the highest ratio of researchers to the economically active population in Latin America. DIVERSITY AND SPECIALIZATION Argentina offers competitive advantages in various segments of the biotechnology industry, particularly in the fields of agriculture, food, and human and animal health. These advantages result from a production pattern with an export profile and strong international presence comprised of more than 120 companies, 8,000 highly qualified workers and excellent technological institutions and poles, including Leloir Institute Foundation, the Experimental Biology and Medicine Institute and the Biomedicine Research Institute of the Scientific and Technological Pole of Buenos Aires. PUBLIC AND PRIVATE SECTOR COOPERATION Prestigious public institutions— including the National Institute for Agricultural Technology (INTA), the National Institute for Industrial Technology (INTI) and the National Agency for Scientific and Technological Promotion (ANPCYT)—are driving biotechnology development in association with the private sector, contributing to innovation through research and development projects. This synergy between public and private institutions is reflected by more than 100 biotechnology projects co-financed by 40 companies, generating investments of AR$ 150 million, as well as in the successful association between laboratories and universities. A HIGHLY QUALIFIED WORKFORCE AND A SOLID INDUSTRIAL TRADITION SUPPORT THE INDUSTRY’S PATTERN OF DIVERSIFICATION AND RECONCENTRATION IN PRODUCTION. THE BIOTECHNOLOGY SECTOR IS COMPRISED OF A CONGLOMERATE OF LOCAL AND MULTINATIONAL COMPANIES, INCLUDING TOP GLOBAL NAMES SUCH AS BASF, BAYER CROP SCIENCE, DOW AGROSCIENCES, MONSANTO AND PIONEER, AS WELL AS SUCCESSFUL LOCAL COMPANIES WITH INTERNATIONAL GROWTH POTENTIAL. MANY OF THESE LOCAL COMPANIES— AMEGA BIOTECH, BIOCERES, BIOGÉNESIS-BAGÓ, BIOSIDUS, CASSARÁ , GADOR, INDEAR, PHARMADN, RIZOBACTER AND WIENER LABORATORIOS— ARE DEVELOPING BIOTECHNOLOGY APPLICATIONS AIMED AT PROMOTING COMPETITIVENESS THROUGH INNOVATION. THE COMBINATION OF INCREASING PUBLIC-PRIVATE JOINT EFFORTS, STRONG R&D CAPABILITIES AND A PATTERN OF DIVERSIFICATION AND RE- CONCENTRATION IN PRODUCTION PLACE THE COUNTRY AS ONE OF THE LEADERS IN THE BIOTECHNOLOGY SECTOR IN LATIN AMERICA, WHERE IT EXCELS FOR ITS SCIENTIFIC AND INNOVATIVE POTENTIAL IN AGRICULTURAL APPLICATION AND HUMAN AND ANIMAL HEALTH. has one of the highest potential for the application of biotechnology processes. To date, biotechnological applications for the food and beverage industry are largely concentrated in the production of high-fructose corn syrup (HFCS), and its intermediate product, glucose syrup, among other ingredients for foodstuffs. Additionally, two of the leading dairy companies have successfully launched probiotic milk lines. Applications in agriculture and human and animal health — Applications in the food industry HIGH YIELDS HUMAN HEALTH AND DIAGNOSIS. OPPORTUNITIES TO EXPLORE With its vast tracts of fertile land, Argentina was one of the first countries to use and produce genetically modified (GM) crops, which offer producers considerable advantages in terms of production and profit levels. Currently, Argentina is the world’s third-largest producer of GM crops (23.7 million hectares, representing 14.8% of GM-cultivated land worldwide), producing record yields in soybean, corn and other byproducts. Argentina is also one of the leading countries in the production of biotechnological soybean, corn, sunflower and cotton seeds with insect-resistant and drought and herbicide-tolerant genes and typologies. There are also several companies based in Argentina that manufacture bioinsecticides and inoculants, and others that are developing technologies for micropropagation and plant tissue cultivation. There is a vast range of opportunities opening up in the area of diagnostics, one of the fastest-growing fields in human health. Currently, developments and products using recombinant proteins and monoclonal antibodies to detect infectious diseases are being made and manufactured locally. Furthermore, cutting-edge research in molecular oncology, leukocyte differentiation antigens, genetic predisposition for hereditary diseases, DNA paternity testing and gene therapy are being carried out locally. QUALITY FOR WELLBEING — Argentina’s highly competitive and integrated food and beverage industry benefits greatly from first-class locally sourced raw materials. This broad-based sector Since the late 1970s, Biosidus has been one of the world leaders in the biotechnology field thanks to the synergy between its technological innovation and business administration capabilities. PHARMACEUTICAL INDUSTRY. ADVANCED DEVELOPMENTS A long tradition in biomedicine has evolved into a developed domestic industry aligned with the World Health Organization’s strictest standards in terms of manufacturing quality and medicine control. Argentine pharmaceutical companies are active at every stage of the production process from research and development to sales and marketing with exports of high quality medicines worldwide. Most of the biotechnology developments come from the application of recombinant DNA. Moreover, Argentina is one of the few countries in the world with pharmaceutical dairy technology and transgenic cloned animals, along with the U.S., Australia, South Korea and New Zealand. — From Argentina to the world — ANIMAL HEALTH. INTERNATIONAL RECOGNITION — Local advances in livestock genetics place Argentina among the best performing countries in terms of artificial insemination, bovine vaccines and multi-species cloning (goats, cows, sheep, bulls, horses and pigs). Local procedures represent the highest production capacity in Latin America. Argentina offers investment opportunities in segments specialized in the production of vaccines, animal feed and cloning, as one of the few countries in the world with the know-how. Biosidus sells seven recombinant proteins used in human healthcare in Argentina as well as in foreign markets and currently has a number of bio-similar products at different stages of development. The quest for increasingly efficient production methods has led the company to build its own pharmaceutical dairy, comprised of cloned animals which produce proteins such as the human growth hormone and human insulin.