P/ACE™ MDQ plus Capillary
Electrophoresis System
Site Planning Guide
B54950AA
February 2015
AB Sciex Pte. Ltd and its affiliates disclaims all warranties with respect to this document,
expressed or implied, including but not limited to those of merchantability or fitness for a
particular purpose. In no event shall AB Sciex Pte. Ltd. and its affiliates be liable, whether in
contract, tort, warranty, or under any statute or on any other basis for special, incidental, indirect,
punitive, multiple or consequential damages in connection with or arising from this document,
including but not limited to the use thereof.
For research use only. Not for use in diagnostic procedures.
The trademarks mentioned herein are the property of AB Sciex Pte. Ltd. or their respective
owners.
AB SCIEX™ is being used under license and SCIEX Separations is a part of AB Sciex.
© 2015 AB Sciex
Find us on the World Wide Web at www.sciex.com.
AB Sciex
500 Old Connecticut Path
Framingham, MA 01701
USA
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Contents
Chapter 1 Safety, Notices and Labels . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5
Overview. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5
General Safety Information. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5
Alerts for Warning, Caution, Important, and Note . . . . . . . . . . . . . . . . . . . . . . . . . 6
Instrument Safety Precautions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6
Chemical and Biological Safety . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8
Moving Parts or Sharp Objects . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8
Disposal of Devices Containing Mercury Components . . . . . . . . . . . . . . . . . . . . . 9
Electrical Safety . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9
Laser Safety (for Optional Laser Device). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
Safety Symbols and Labels. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
High Voltage Electric Shock Risk Symbol . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
Attention Safety Symbol . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
Sharp Object Label . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
Laser Light (for Optional Laser Device). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
Protective Earth or Ground Terminal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
Fuse Warning Symbol. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
Off Position of Convenience Switch. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
On Position of Convenience Switch . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12
For Research Use Only . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12
RoHS Notices . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12
China RoHS Caution Label. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12
China RoHS Environmental Label . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12
Other Instrument Labels . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
Recycling Label (WEEE) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
CE Mark Label . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
RCM Label . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14
CSA Mark Label . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14
Chapter 2 Pre-Installation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15
About This Guide . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15
Preparation Check List . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15
Technical Support . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15
Pre-Installation Check List . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16
Computer. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16
Detectors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16
Options . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17
Chapter 3 Site Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19
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Physical Layout Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .19
Recommended Bench Space . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .20
Ventilation Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .20
Access to Mains Supply Connector . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .20
Other Environmental Requirements. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .21
Electrical Requirements. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .21
Chapter 4 Specifications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .23
P/ACE MDQ™ plus Instrument Specifications . . . . . . . . . . . . . . . . . . . . . . . . . .23
Sample Temperature Control . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .24
Capillary Temperature Control . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .24
Pressure and Vacuum System . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .24
Computer Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .25
Detector Specifications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .25
UV Detector . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .25
Photo Diode Array (PDA) Detector (Optional) . . . . . . . . . . . . . . . . . . . . . . . . .26
Laser Induced Fluorescence (LIF) Detector (Optional). . . . . . . . . . . . . . . . . . .26
Chapter 5 Training . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .27
Pre-Training Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .27
Additional Training . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .27
Revision History . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .29
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CHAPTER 1
Safety, Notices and Labels
Overview
A description of the symbols and labels that are used on the SCIEX P/ACE™ MDQ plus Capillary
Electrophoresis System, or that are shown in this guide, can be found in this section.
Do not attempt to perform any procedure before carefully reading all instructions. If in doubt as
to how to proceed in any situation, contact your Sciex representative.
General Safety Information
To prevent personal injury or system damage, read, understand, and obey all safety precautions,
warnings in this guide, and labels on the instrument. These labels are shown with internationally
recognized symbols. Failure to heed these warnings could result in serious injury. This safety
information is intended to supplement federal, state, provincial, and local environmental health
and safety (EHS) regulations. The information provided covers system-related safety with regard
to the operation of the instrument. It does not cover every safety procedure that should be
practised. Ultimately, the user and the organization are responsible for compliance with federal,
state, provincial, and local EHS regulations and for maintaining a safe laboratory environment.
For more information, refer to the appropriate laboratory reference material and standard
operating procedures.
Sciex urges its customers and employees to comply with all national health and safety standards
such as the use of barrier protection. This may include, but is not limited to, protective eyewear,
gloves, and suitable laboratory attire when operating or maintaining this or any other automated
laboratory instrumentation.
WARNING
If the equipment is used in a manner not specified by Sciex, the
protection provided by the equipment may be impaired.
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Alerts for Warning, Caution, Important, and Note
All warnings and cautions in this guide include an exclamation point, framed within a triangle.
The exclamation point symbol is an international symbol which serves as a reminder that all safety
instructions should be read and understood before installation, use, maintenance, and servicing are
attempted.
WARNING
WARNING indicates a potentially hazardous situation which, if not
avoided, could result in death or serious injury. It may also be used to
indicate the possibility of erroneous data that could result in an incorrect
determination. May be used to indicate the possibility of severe
instrument damage.
CAUTION
CAUTION indicates a potentially hazardous situation, which, if not
avoided, may result in minor or moderate injury. It may also be used to
alert against unsafe practices. May be used to indicate the possibility of
erroneous data that could result in an incorrect determination.
IMPORTANT Used for comments that add value to the step or procedure being
performed. Following the advice in the Important adds benefit to the
performance of a piece of equipment or to a process.
NOTE Used to call atttention to noteable information that should be followed
during installation, use, or servicing of this equipment.
Instrument Safety Precautions
WARNING
Risk of operator injury if:
•
All doors, covers and panels are not closed and secured in place
prior to and during instrument operation.
•
The integrity of safety interlocks and sensors is compromised.
•
You contact moving parts.
•
You mishandle broken parts.
•
Doors, covers and panels are not opened, closed, removed and/or
replaced with care.
•
Improper tools are used for troubleshooting.
To avoid injury:
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•
Keep doors, covers and panels closed and secured in place while the
instrument is in use.
•
Take full advantage of the safety features of the instrument. Do not
defeat safety interlocks and sensors.
•
Acknowledge and act upon instrument alarms and error messages.
•
Keep away from moving parts.
•
Report any broken parts to your Sciex representative.
•
Use the proper tools when troubleshooting.
CAUTION
System integrity could be compromised and operational failures could
occur if:
•
This equipment is used in a manner other than specified. Operate the
instrument as instructed in the system documentation.
•
You introduce software that is not authorized by Sciex into your
computer. Only operate your system’s computer with software
authorized by Sciex.
•
You install software that is not an original copyrighted version. Only
use software that is an original copyrighted version to prevent virus
contamination.
CAUTION
If you purchased this product from anyone other than Sciex or an
authorized Sciex distributor, and, if it is not presently under a Sciex
Service Maintenance Agreement, Sciex cannot guarantee that the
product is fitted with the most current mandatory engineering revisions
or that you will receive the most current information bulletins
concerning the product. If you purchased this product from a third party
and would like further information concerning this topic, contact your
Sciex representative.
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Chemical and Biological Safety
WARNING
Normal operation of the system can involve the use of solvents and
reagents that are toxic, flammable, or biologically harmful.
•
Observe all precautionary information printed on the original
solution containers.
•
Operate the system in the appropriate environment.
•
Take all necessary precautions when using pathology or toxic
materials to prevent the generation of aerosols.
•
Observe all applicable precautionary procedures when using
flammable solvents in or near the instrument.
•
Wear appropriate laboratory attire, for example, safety glasses,
gloves, lab coat and breathing apparatus, when working with
hazardous materials.
•
Dispose of all waste solutions in a proper manner.
Moving Parts or Sharp Objects
WARNING
Risk of personal injury. To avoid injury due to moving parts, observe the
following:
•
Never attempt to exchange labware, reagents, or tools while the
instrument is operating.
•
Never attempt to physically restrict any of the moving components of
the instrument.
•
Keep the instrument work area clear to prevent obstruction of the
movement.
Moving parts are limited to the sample handling system. Plate movement is safety interlocked
through the sample access cover. To avoid injury due to moving parts, observe the following:
•
Keep loose clothing and hair away from the plate area.
•
Never attempt to physically restrict movement of the plate assembly.
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Disposal of Devices Containing Mercury Components
This product contains a mercury-added part. Recycle or dispose of according to local, state, or
federal laws. It is very important that you understand and comply with the safe and proper disposal
of devices containing mercury components (switch, lamp, battery, relay, or electrode). The
mercury component indicator label can vary depending on the type of device.
Electrical Safety
WARNING
A high voltage power supply is used with this instrument. Safety
interlocks disable high-voltage output while the capillary access cover is
open and remove the risk of shock while performing routine instrument
functions. However, removal of any panel may expose an individual to
the possibility of severe electrical shock and/or mechanical injury. For
this reason, any service requiring removal of a panel or otherwise
overriding or disabling safety interlocks must be done by Sciex
personnel only.
To prevent electrically related injuries and property damage, properly inspect all electrical
equipment prior to use and immediately report any electrical deficiencies. Contact a Sciex
representative for any servicing of equipment requiring the removal of covers or panels.
To reduce risk of electrical shock, all devices employ a three-wire electrical cable and plug to
connect the equipment to the electrical mains supply and protective earth.
•
Make sure that the wall outlet receptacle is properly wired and connected to protective earth.
•
Make sure there is clear access to the mains supply connector on the instrument. The
connector must be accessible to disconnect the instrument from the electrical mains supply.
•
Do not use a three-to-two wire plug adapter.
•
Do not use a two-wire extension cord or a two-wire multiple-outlet power strip.
•
Disconnect the electrical mains supply cord from the system before performing maintenance.
•
Do not remove any panels; panels should be removed only by qualified service personnel.
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Laser Safety (for Optional Laser Device)
WARNING
The laser (optional) is designated as “Class 3B.” The “3B” classification
means that “direct intrabeam viewing of this type of laser is always
hazardous to personnel.”
The laser (optional) and several other integral components are housed in
a sealed container that together comprise the laser assembly. The laser
assembly has no user serviceable parts. Service of the laser assembly is
restricted to certified Sciex Field Service Employees (FSEs).
During normal operation of the system, laser light is not accessible to
the user. Therefore, the overall laser classification of the CE Instrument
is “Class 1,” defined as “lasers which are safe under reasonably
foreseeable conditions of operation.”
To prevent users from potentially harmful laser light, observe all safety
warnings and NEVER REMOVE THE OUTER CASING OF THE LASER
ASSEMBLY.
Safety Symbols and Labels
High Voltage Electric Shock Risk Symbol
This symbol indicates that there is high voltage and there is a risk of electric shock, and the
operator should use care when accessing this area.
Attention Safety Symbol
This symbol calls attention to important information to read, or is accompanied by another symbol
indicating a particular safety hazard. The information is located either on the label with the symbol
or in the P/ACE MDQ plus system documentation.
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Sharp Object Label
This symbol indicates that there are sharp objects, and the operator should use care when
accessing this area.
Laser Light (for Optional Laser Device)
This product may contain a laser-added part. A separate guide included with that part will indicate
that potential hazard to your personal safety exists from a laser source. The laser indicator label
can vary depending on the type of device.
Protective Earth or Ground Terminal
This symbol identifies the location of the protective earth or ground terminal on the equipment.
Fuse Warning Symbol
This symbol indicates that the instrument fuse may be replaced only with the specified type and
rating.
Off Position of Convenience Switch
This symbol graphically represents the equipment convenience push-button switch when it is in
the off position.
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On Position of Convenience Switch
This symbol graphically represents the equipment convenience push-button switch when it is in
the on position.
For Research Use Only
This label indicates that the system is for research use only and should not be used in diagnostic
procedures.
RoHS Notices
These labels and materials declaration table (the Table of Hazardous Substance’s Name and
Concentration) are to meet People’s Republic of China Electronic Industry Standard SJ/T113642006 “Marking for Control of Pollution Caused by Electronic Information Products”
requirements.
China RoHS Caution Label
This label indicates that the electronic information product contains certain toxic or hazardous
substances. The center number is the Environmentally Friendly Use Period (EFUP) date, and
indicates the number of calendar years the product can be in operation. Upon the expiration of the
EFUP, the product must be immediately recycled. The circling arrows indicate the product is
recyclable. The date code on the label or product indicates the date of manufacture.
China RoHS Environmental Label
This label indicates that the electronic information product does not contain any toxic or
hazardous substances. The center “e” indicates the product is environmentally safe and does not
have an Environmentally Friendly Use Period (EFUP) date. Therefore, it can safely be used
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indefinitely. The circling arrows indicate the product is recyclable. The date code on the label or
product indicates the date of manufacture.
Other Instrument Labels
This section provides information for some labels and symbols appearing on the P/ACE MDQ
plus instrument housing. These labels and symbols may be associated with user-serviceable
procedures. Individual hazards associated with a specific procedure in this guide may use these
labels and symbols, and are included in Warnings or Cautions within the procedures for that task.
Recycling Label (WEEE)
The symbol of a crossed-out wheeled bin on the product is required in accordance with the Waste
Electrical and Electronic Equipment (WEEE) Directive of the European Union.
The presence of this marking on the product indicates:
•
That the device was put on the European Market after August 13, 2005 and
•
That the device is not to be disposed via the municipal waste collection system of any member
state of the European Union.
For products under the requirement of WEEE directive, please contact your dealer or local Sciex
office for the proper decontamination information and details on the take back program that
facilitates proper collection, treatment, recovery, recycling, and safe disposal of this device.
CE Mark Label
The CE symbol is a conformity marking indicating that the P/ACE MDQ plus instrument meets
the requirements of applicable European Conformity directives within the European Economic
Area (EEA).
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RCM Label
The RCM symbol on the P/ACE MDQ plus instrument is an identification marking that indicates
this instrument is compliant with the Australian Communications and Media Authority’s
(ACMA) regulatory arrangements for telecommunications, radio, EMC and electromagnetic
energy (EME) requirements. This symbol is required on this instrument for the Australian and
New Zealand markets.
CSA Mark Label
The CSA symbol on the P/ACE MDQ plus instrument indicates that the instrument has been
certified by a Nationally Recognized Testing Laboratory (NRTL) to applicable Laboratory
Equipment Safety Standards for the United States and Canada.
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CHAPTER 2
Pre-Installation
About This Guide
This Site Planning Guide assists designated operators in identifying the items required for
laboratory preparation so that the installation of the SCIEX P/ACE™ MDQ plus Capillary
Electrophoresis System can be completed efficiently.
The supplies you must have on hand prior to the installation of the instrument are specified. Also
provided is a list of accessories available.
For your convenience, a checklist is included to help you prepare for the installation.
Preparation Check List
The following is a summary of the items that must be addressed prior to installation. Mark each
item as it is completed. When these prerequisites have been met, contact your local Sciex
representative to schedule the installation.
•
Appropriate table or bench (Recommended Bench Space on page 20)
•
Suitable electrical mains supply (Table 4.1 on page 23)
•
Suitable laboratory environment (Table 4.1 on page 23)
•
Training prerequisites met (Training on page 27)
Technical Support
If you encounter a problem that is not discussed in this guide, and you need technical support,
contact your Sciex representative using the information below.
NOTE When you call your local dealer or Sciex, be sure to have your registration
material, instrument serial number, and software version number available.
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Table 2.1 Technical Support Information
Instrument Serial Number:
P/ACE MDQ plus Software Version:
Firmware Version:
Dealer Name:
Dealer Phone Number:
Mail
AB Sciex
500 Old Connecticut Path
Framingham, MA 01701
USA
Web Address:
www.sciex.com
Pre-Installation Check List
The following is a list of requirements and items necessary for installation of the P/ACE MDQ
plus system. Use this list to check off the requirements and items you have and other items as you
receive them. To ensure a successful installation, please verify that you have these items prior to
scheduling the installation with your local office.
P/ACE MDQ plus Instrument
•
Electrical mains supply requirements
•
Bench space
•
Capillary Test Kit PN 33843 (must be ordered separately)
Computer
•
Supplied by Sciex (or equivalent computer system)
•
Windows 7
•
P/ACE MDQ plus software with 32 Karat software
•
Printer (Optional)
•
GPIB communications interface (USB-GPIB cable)
•
UV/VIS detector
•
PDA detector (if ordered)
•
LIF detector (if ordered)
Detectors
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Options
•
Filters (spare for each filter)
•
Lasers (if ordered)
•
External detector adapter (if ordered)
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CHAPTER 3
Site Requirements
Physical Layout Requirements
The SCIEX P/ACE™ MDQ plus system consists of the P/ACE MDQ plus instrument, a
computer, 22 inch monitor, keyboard, and mouse. Instrument dimensions are shown in Figure 3.1
Figure 3.1 P/ACE MDQ plus Instrument Dimensions
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Recommended Bench Space
In addition to space for the instrument itself, additional space for the computer and printer (if any)
is required.
Table 3.1 Minimum Bench Footprint
Length
1.8 m (6 feet)
Width
91.4 cm (3 feet)
Height Allowance
1.07 m (3 1/2 feet)
Supportable Weight
227 kg (500 lbs)
Laboratory Layout
Figure 3.2 illustrates the recommended system setup.
Figure 3.2 Typical P/ACE MDQ plus System Setup
Ventilation Requirements
Adequate space must be provided around instrument for ventilation and access to the
communications connector. Allow least 4 inches clearance on all sides.
Access to Mains Supply Connector
Make sure there is clear access to the mains supply connector on the instrument. The connector
must be accessible to disconnect the instrument from the electrical mains supply.
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Other Environmental Requirements
Refer to Table 4.1 P/ACE MDQ plus Instrument Specifications on page 23 for humidity, altitude,
temperature requirements.
Electrical Requirements
The P/ACE MDQ plus system is shipped with a mains supply cord suitable for North America
(nominal 120 VAC, 60 Hz) installations. A mains supply cord suitable for non-North America
installations will be provided by Sciex. The instrument requires one grounded electrical mains
supply outlet.
The electrical mains supply to the laboratory should connect directly from an electrical line
transformer at a supply known to be clear of erratic power loads, spikes, and electromagnetic
interference. Electrical supplies reserved for the instrument must have adequate reserve capacity.
Normal loading should not exceed 50% of nominal capacity to allow for start-up loads and the
addition of new instruments.
A total of three grounded electrical mains supply outlets are required for the computer, the monitor
and the P/ACE MDQ plus system. Any additional accessories, such as a printer, will require
additional electrical mains supply outlets.
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CHAPTER 4
Specifications
Use this information to prepare the environment where the system is to be located.
P/ACE MDQ™ plus Instrument Specifications
Table 4.1 P/ACE MDQ plus Instrument Specifications
Specification Type
Description
Weight
85.3 kg (188 lbs)
Firmware Version
10.2 or higher
Electrical Mains Supply Requirements Supply voltage must not exceed 10% of nominal
P/ACE MDQ plus instrument
100 VAC to 240 VAC, 8.0 A, 50/60 Hz; auto-sensing
voltage power supply
PC (typical)
6.0 A, 50/60 Hz
Monitor (22 inch)
1.5 A, 50/60 Hz
Fuses
T8.0 A 250 V 5 mm x 20 mm glass cartridge (2 ea.)
Maximum Heat Dissipation (to room)
400 W (1365 BTU/hour)
Ambient Operating Temperature
Range
Operational: 5°C to 40°C (41°F to 104°F)
Recommended for performance: 15°C to 30°C
(59°F to 86°F)
Relative Humidity Range
<80% (non-condensing) up to 30°C (59°F), decreasing
linearly to 50% at 40°C (104°F)
Altitude Restrictions
Up to 2000 m (6562 ft)
Installation Category
Category II
Pollution Degree
2
Sound Pressure Level
Maximum: 75 dB
Maximum at 1 meter: 66 dB
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Sample Temperature Control
Table 4.2 Sample Temperature Control Specifications
Specification Type
Description
Temperature Range
From 20°C below ambient to 60°C (140°F)
Minimum setting: 4°C (39°F)
Temperature Stability
±1°C at 25°C
±3°C at 4°C and 60°C
Temperature Accuracy
±2°C within ±15°C of ambient temperature
±3°C outside of ±15°C of ambient temperature
Response Time
Temperatures between ambient and 20°C below ambient: 120
minutes
Temperatures between ambient and 60°C (140°F): 120 minutes
Capillary Temperature Control
Table 4.3 Capillary Temperature Control Specifications
Specification Type
Description
Temperature Range
From 10°C belowambient to 60°C (140°F)
Minimum setting: 15°C (59°F)
Temperature Stability
±1°C at 25°C
Temperature Accuracy
±1°C within ±5°C of ambient temperature
±2°C outside of ±5°C of ambient temperature
Response Time
Temperatures between ambient and 10°C below ambient:
45 minutes
Temperatures between ambient and 60°C (140°F): 45 minutes
Pressure and Vacuum System
Table 4.4 Pressure and Vacuum System Specifications
Specification Type
Description
Pressure Range
Injection: 0.1 psig to 25 psig (pressure) or 0.1 psig to 5.0 psig
(vacuum)
Rinse: 0.1 psig to 100.0 psig (pressure) or 0.1 psig to 5.0 psig
(vacuum)
Pressure Accuracy
±0.3 psi at 25 psi
±1.0 psi at 100 psi
Pressure Direction
Applied at inlet or outlet for all pressure functions, rinses and
injections. User-selectable from software.
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Computer Requirements
Table 4.5 Computer Specifications
Item
Description
CPU
Lenovo PC (validated on M82 model)
Memory
4 GB
Hard Drive
320 GB or larger
CD/DVD RW
Required
USB Ports
2 open ports (one for license key and one for GPIB)
Monitor
Size: 22 inch
Resolution: 1680 x 1050
Color: True Color
Keyboard and Mouse
Microsoft compatible
Interface
GPIB Data Communications Interface USB cable (National
Instruments)
Operating System
Microsoft Windows 7 (32-bit) with Service Pack 1
Software
P/ACE MDQ plus software version 10.2 (includes 32 Karat
software)
IMPORTANT Users must have Administrator or Power user permission on the
local workstation.
IMPORTANT Install 32 Karat software in the C:\32Karat folder.
Detector Specifications
UV Detector
Table 4.6 UV Detector Specifications
Specification Type
Description
Filter Selection
200 nm, 214 nm, 230 nm, and 254 nm (standard) with three
open positions for additional filters.
Filter Dimensions
Diameter: 0.5 inch (1.27 cm)
Thickness: 0.20 inch (5 mm)
Filter Bandwidth
10 nm nominal
UV Source
30 W pre-aligned deuterium lamp
UV Source Lifetime
1000 hours
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Photo Diode Array (PDA) Detector (Optional)
Table 4.7 PDA Detector Specifications
Specification Type
Description
UV Source
30 W pre-aligned deuterium lamp
UV Source Lifetime
1000 hours
Detector Wavelength Range
190 nm to 600 nm
Detector
256 element diode array
Detector Wavelength Accuracy
2 nm
Bandwidth
6 nm minimum (absorbance averaging)
Scan Collection Frequency
0.5 Hz to 32 Hz
Laser Induced Fluorescence (LIF) Detector (Optional)
Table 4.8 LIF Detector Specifications
Specification Type
Description
Relative Fluorescence Units (RFU)
Range
0 RFU to 1000 RFU
Dynamic Range
>104
(at a dynamic range setting of 1000)
Sensitivity
1 x 10-11 1 M sodium fluorescein with a signal-to noise
ratio >2
Baseline Noise
<0.005 RFU peak to peak (Specifications are for an
OPCAL with probe guide/lens.)
Baseline Drift
<0.2 RFU per hour
Wavelength Ranges (for optics)
Excitation: 300 nm to 700 nm
Emission: 350 nm to 750 nm
Filters (optional)
For 488 nm laser: 488 nm notch filter and 520 nm bandpass filter
For user-supplied lasers: Two filters are required: a laser
filter to block stray laser light and an emission filter to
select the wavelength of the emitted light. Both filters
must have an outside diameter of 0.500 inch
(+0.000 inch, -0.010 inch) and a thickness
0.350 inches. If multiple filters are used in a single
channel, the total thickness cannot exceed 0.350 inches.
Laser
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3 mW, 488 nm solid state laser
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CHAPTER 5
Training
Pre-Training Requirements
After the system has been installed, a Sciex Field Service Employee will train up to two operators
in basic instrument operation.
Successful implementation of the installation is dependent upon the training environment. To
ensure a focused and optimized training session, follow these guidelines:
1. It is important that the operators are available and uninterrupted throughout the initial training
period.
2. No more than two operators can be trained on the instrument at any given time.
System operation requires a basic knowledge of Windows 7. The operator must have the following
skills:
•
Use Add/Remove programs
•
Create, open, save, edit, move, and copy files
•
Perform disk management operations
Additional Training
Our training program has been designed in phases to allow operators to focus on and master basic
operational elements. The first phase involves the use of the P/ACE MDQ plus system electronic
guides.
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Revision History
Initial Issue, B54950AA, February 2015
P/ACE MDQ plus Software version 10.2.x (includes 32 Karat software)
P/ACE MDQ plus Firmware version 10.2.x
This guide applies to the latest software and firmware listed above, and any higher subsequent
versions. When a subsequent software or firmware version affects the information in this guide, a
new issue will be released to the Sciex web site. For updates, go to www.sciex.com and download
the latest version of the guide.
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