CleanLogix Application Note AN1002 Scouring and Surface Preparation of Silicone Rubbers (and other materials) APPLICATION NOTE By David Jackson Application Note AN1002 © CleanLogix All Rights Reserved \ Introduction to Silicone Rubbers Figure 1 shows a molecular model for polydimethylsiloxane or PDMS, a common silicone polymer. Cured silicones are an elastomer (a rubber-like material) composed of siloxanes; silicon together with carbon, hydrogen, and oxygen. Silicone rubbers are widely used in industry, and there are multiple formulations. Silicone rubbers are often one- or two-part polymers, and may contain fillers or additives to improve properties or reduce cost. Silicone rubber is generally nonreactive, stable, and resistant to extreme environments and temperatures from −55 °C to +300 °C while still maintaining its useful mechanical and chemical properties. Due to these properties and its ease of manufacturing and shaping, silicone rubbers can be found in a wide variety of products, including: aerospace Figure 1 3-D Molecular Model for PDMS applications such as electronic cabling, vibration dampers and electrical device insulators; biomedical devices and implants; and pharmaceutical devices such as seals, liners and septa. During manufacture, heat may be required to vulcanize (set or cure) the silicone into its rubber-like form. This is normally carried out in a two stage process at the point of manufacture into the desired shape, and then in a prolonged post-cure process. Silicones can also be injection molded and can include special monomer chemistries and properties such as fluorinated chemistry, steam resistant, metal detectable, fluorescent, electrically conductive, chemically resistant, low-smoke emitting, and flame-retardant. Example physical properties of a silicone rubber (e.g., LSR Polymax 2005) are shown in Table 1. Mechanical Properties Hardness, shore A Tensile strength Elongation at break Maximum temperature Minimum temperature 10–90 11 N/mm² 100–1100% +300 °C −120 °C Table 1 Example Silicone Rubber Properties CleanLogix Application Note AN1002 Silicone Rubber Contamination Following conventional liquid silicone rubber (LSR) molding and curing processes, and depending upon the type and amount of additives, cure cycle times and conditions; solidified rubber products can contain up to 10% (by weight) residual unreacted monomer fragments (called “oligomers”), fillers and other interstitial residues; more simply termed “silicone contamination” for the purposes of this application note. Silicone contamination is generally non-toxic, biocompatible, non-corrosive, and non-volatile under standard temperature and pressure conditions (STP). However portions of it can migrate to the surface or out of the material entirely, when the surface is cleaned or exposed to non-steady state environmental conditions in accordance with Fick’s molecular diffusion principle. Residual silicone contamination can usually be left within the bulk solidified material for many industrial and commercial applications, and may in fact be required for the desired performance properties. However silicone contamination, in particular volatile or mobile forms, can be problematic in certain applications or systems involving biomedical, aerospace, and pharmaceutical devices employed in aqueous, solvent or vacuum environments. For example, silicone oligomers (considered a “leachable” contaminant) can be extracted from silicone rubbers located within aqueous or solvent environments and volatilized (considered an “outgas” contaminant) when situated within hot and/or vacuum environments. Examples of situations and environments where silicone contamination poses a potential threat include vacuum systems, thermal systems, space environment, the human body, or as components of containers used to store liquids. Moreover, silicone contamination can present problems during manufacturing processes such as plasma surface modifications and materials joining. Silicone contamination is also a contamination concern in critical manufacturing environments, for example cleanrooms used to fabricate semiconductor chips and hard disk drives. Aerospace, Pharmaceutical, and Medical Products Application Note AN1002 © CleanLogix All Rights Reserved \ For example, in spacecraft applications silicone oligomers will “outgas” from the pores of the bulk material under the absolute vacuum of space, migrating along internal thermal gradients created by the spacecraft rotation into and away from the Sun. This can relocate silicone contamination into or onto critical optoelectronic systems such as navigational or observation devices, causing potential optical surface obscuration. In another example, the performance of heat exchange surfaces can be negatively affected if coated with thin heatinsulating layers of silicone contamination and other forms of “volatile condensable matter” or VCM. In pharmaceutical applications, silicone contamination can be leached from container seals or septa by solvent-based diluents. In medical applications, silicone contamination can leach from a silicone rubber device such as tubing or sleeves and cause unwanted cellular responses or cellular adhesion problems. Still moreover, subsurface silicone contamination will migrate from the interior of the bulk substrate and onto the surface regions during vacuum-based processes such as plasma treatment, interfering with the formation of clean functionalized surfaces or shortening the longevity of same. Finally, surfaces containing silicone contamination interfere with adhesive bonding mechanisms, preventing the formation of strong chemical and mechanical adhesive bonds. One of the difficulties in modifying silicone surfaces relates to the mobile nature of amorphous polymer molecules. For example, during surface modification, for example oxidation, of a silicone rubber surface, molecular motions can (over a period of time) cause the modified surface to intermingle and diffuse into the CleanLogix Application Note AN1002 polymer matrix. This tendency is most pronounced in silicone elastomers which have very mobile polymer chains. To overcome this problem, plasma treatments may be used to crosslink and stabilize the polymeric surface. However, within hours or even minutes after plasma treatment, the surface begins to revert back to its original hydrophobic state. Uncrosslinked oligomers and low molecular weight oils begin to migrate to the polymeric surface in accordance with Fick’s law of molecular diffusion - migration of polymers from interior regions of high concentration to exterior surface regions having a low concentration. These oils tend to interfere with attachment or grafting of coatings to the polymer surface in the case of plasma coating. These oils also prevent the formation of strong chemical and mechanical adhesive bonds in adhesive bonding applications. Conventional Silicone Rubber Treatment Solutions There are generally three conventional treatment methods used to clean, scour, or fully-react silicone substrates, respectively, described as follows: • • • Solvent Extraction Thermal Vacuum Bakeout Enhanced Silicone Curing Processes Solvent extraction using organic solvents or solvent blends can be a very slow process, and can alter the mechanical properties of certain silicone devices. Extraction with toxic or flammable solvents on a large scale is dangerous and consumes significant amounts of energy. Moreover, residual extraction solvent residues left in the pores of the silicone rubber can be problematic to the function or performance of the extracted device. An alternative to solvent extraction is thermal vacuum bakeout or TVB. The TVB process extracts oligomers from the bulk polymer using a high vacuum (i.e. less -5 than 1x10 Torr) and heat (i.e., 125 deg. C) over an extended period of time. TVB extraction proceeds somewhat slowly - for example up to 80 hours or more and usually degrades the mechanical properties of the silicone rubber due to accelerated thermal aging. In addition, TVB-treated silicone rubbers can burn or exhibit color change. Conventional Solvent Extraction using a “Soxhlet Extractor” An alternative to post-treat methods is more complete vulcanizing or curing to convert most of the silicone monomer into solid polymer. These methods include peroxide (free radical) and platinum (addition) curing techniques. However, these curing processes create constraints as well. Peroxide curing can lead to microscopic bubbles, surface darkening and a tackier surface (i.e., can pick up more dirt). Platinum curing is a cleaner but a more expensive treatment process and is typically used only in critical applications such as medical implants – socalled medical grade silicones. Also, platinum-cured silicones exhibit higher wear rates and spallation relative to peroxide-cured silicones when used in mechanical devices such as pumps. As such, all conventional silicone rubber treatment methods (i.e., post-treatment and curing methods) offer tradeoffs in terms of processing time, life-cycle costs and end-product performance. Application Note AN1002 © CleanLogix All Rights Reserved \ A newer treatment technique that is generally unknown or not well understood by silicone device manufacturers is carbon dioxide processing, or simply “CO2 Processing”. CO2 processing uniquely employs one or a combination of solid, liquid, supercritical, and plasma CO2 chemistries and processes to treat silicones, CleanLogix Application Note AN1002 as well as many other types of substrates requiring dry scouring and/or surface treatment. CO2 processing offers silicone device manufacturers a robust, lean and green cleaning (and surface treatment) option that can provide distinct economic and performance advantages relative to the conventional treatment processes. CO2 processing of silicone rubbers using supercritical and liquid CO2 was first developed in the 1980’s at Hughes Aircraft to prepare materials for use in high reliability commercial and military communications satellites and spacebased warfare systems, enabling silicone devices to operate in the harsh environment of space without contaminating and degrading the performance of critical flight hardware. The CO2 Alternative Our CO2 processing technology provides silicone (and other biomedical polymer) device manufacturers a robust platform of post-cure or post-process substrate treatment options, and includes: • • • Centrifugal CO2™ Immersion-Extraction Cleaning CO2 Composite Spray™ Cleaning CO2 Plasma Blast™ Surface Modification Centrifugal CO2™ Immersion-Extraction Cleaning Dense phase (liquid and supercritical) CO2 is a non-toxic solvent that dissolves many types of organic films and oils, and is particularly suited to dissolving and removing unreacted silicone oils. Near-zero or zero (supercritical state) surface tension and low viscosity allows dense phase CO2 to penetrate microscopic pores and crevices, delivering solvent cleaning power deep into the interior of silicone rubber. With our patented Centrifugal CO2™ immersion-extraction cleaning processes, contamination is rapidly removed from silicone rubber under both physical (centrifugal pumping and scouring) and chemical cleaning actions. Figure 2 shows a typical immersion-extraction profile for PDMS using a Centrifugal CO2 cleaning process employing liquid CO2.to meet ASTM E 595 outgas performance criteria - total mass loss (TML) of < 1.00 % and collected volatile condensable material (CVCM) of < 0.10%. CO2 Treatment Chemistries Solid, Liquid, Supercritical and Plasma (Top-to-Bottom) Application Note AN1002 © CleanLogix All Rights Reserved Centrifugal CO2 cleaning processes employ either liquid or supercritical CO2 and require no special permits even from the tough SCAQMD or EPA because it is non-toxic, non-flammable, and non-VOC. Integrated CO2 distillation recycles nearly 100% of the CO2 extraction solvent while separating and concentrating silicone oils (and solvent modifiers if present). Optionally, Centrifugal CO2 processes can be hybridized with other treatment processes such as lowpressure plasma to provide cleaned-surface modifications, bio-burden reduction, or to assist with outgassing and decomposing residual interstitial contaminants. Any “Industry Approved” or “Mil-Spec” extraction cleaning solvent additive may be used with the Centrifugal CO2 process as a “carbonated” prewash-extraction agent or CO2 chemistry modifier, providing numerous novel and dry immersionextraction cleaning chemistries. This would be important when a particular cleaning-extraction chemistry is needed that mimics a particular solvent environment (polar, non-polar, ionic) in which the processed substrate will be exposed; for example a specific pharmaceutical drug solvent carrier. This allows for the continued use of a “spec’d in” immersion-extraction cleaning solvent chemistry – but in a safer and more robust cleaning process. CleanLogix Application Note AN1002 Finally, our CO2 Composite Spray™ and CO2 Plasma Blast™ Particle-Plasma surface treatment processes serve as adjuncts or alternatives to the Centrifugal CO2 process; providing a very robust surface treatment platform capability, and are described below. Silicone Extraction Profile 2.50% % TML 2.00% 1.50% ASTM E 595 1.00% TML CVCM WVR 0.50% 0.77% 0.01% 0.29% 0.00% 0 10 20 30 40 50 Time (minutes) Figure 2 TML Profile for PDMS CO2 Composite Spray™ Cleaning CO2 Composite Spray™ Treatment The cleaning phenomenon involved in our CO2 Composite Spray™ cleaning technology are analogous to (line-of-sight) high-pressure spray cleaning using halogenated solvents such as HFE 7100. For example, one similarity is the high density (1.6 g/cm3) of the solid CO2 solid particles entrained in an inert heated propellant fluid such as CDA. CO2 Composite Spray surface cleaning is a nonabrasive process because of the low hardness of the CO2 particles (less than 1 Mohs) as compared to most conventional manufacturing substrates. Moreover, and similar to high-pressure solvent spray cleaning, CO2 Composite Spray cleaning provides physical momentum transfer (shear stress) and unique phase change phenomenon (solidliquid) – providing scouring liquid solvent cleaning action at the contact surface to simultaneously remove both particulate and thin film oily contamination from a surface. A CO2 Composite Spray exhibits halogenated solvent-like chemistry which provides both physical scouring and chemical cleaning action for contaminated surfaces. A CO2 Composite Spray can be adjusted in several dimensions – with key process variables including pressure, temperature, particle size and concentration – to provide a range of impact shear stresses and cleaning effects. In addition, a CO2 Composite Spray can be modified with liquid, gas and solid additives to provide a range of surface cleaning chemistries and modification capabilities. Figure 3 demonstrates the removal of microscopic inorganic metal oxidation residues from the surfaces of a laser welded titanium neurostimulator lead using a CO2 Composite Spray. Application Note AN1002 © CleanLogix All Rights Reserved Finally, the CO2 Composite Spray process can be further enhanced by hybridizing it with atmospheric plasma - a patented and patents-pending method called CO2 Plasma Blast™. CleanLogix Application Note AN1002 Figure 3 Removal of Ti Weld Soot (Metal Oxides on Neurostimulator Lead) CO2 Plasma Blast™ Treatment The surface scouring and solvent cleaning actions of a CO2 Composite Spray™ are used in cooperation with atmospheric plasma CO2 (and other types of plasma) to form a very robust surface cleaning and preparation treatment called The CO2 Plasma Blast™ process is an atmospheric CO2 Plasma Blast™. hybrid particle-plasma surface ablation (i.e., treatment, transformation and modification) process that combines electron and/or photon driven surface ablation phenomena comprising an ionizing-heating plasma plume with simultaneous surface scouring and cooling actions provided by the CO2 Composite Spray. Figure 4 demonstrates the significant improvement in light cured acrylic adhesive bond strength for a low surface energy polymer (e.g., LDPE) using the CO2 Plasma Blast treatment process. CO2 Particle-Plasma Treatment In this patent-pending surface treatment technique, the CO2 Composite Spray is used to both precisely control surface temperature and cleanliness; the simultaneous removal of heat contamination and processing debris such as oxidation residues, gases, and ablated surface particles generated by the atmospheric plasma process. Working in cooperation, atmospheric plasma cracks and chemically alters the surface while CO2 particles and fluids simultaneously vector surface debris and excess heat from the treated surface. Application Note AN1002 © CleanLogix All Rights Reserved Figure 4 Improvement in Shear Strength CleanLogix Application Note AN1002 Conclusion Conventional pre- and post-treatment options for silicone rubbers pose different constraints in terms cost of ownership, environmental, and material performance. The CO2 alternative offers a robust platform for processing silicone rubbers for medical, aerospace and pharmaceutical applications, as well as many other types of polymers and surfaces requiring scouring and surface modification for manufacturing processes such as bonding, coating and precision assembly. For example, low energy polymers such as LDPE have been processed successfully using CO2 processes. Applicable Industries Aerospace/Defense Medical Electro-Optical Microelectronic Applicable CO2 Technology Centrifugal CO2™ CO2 Plasma Technology CO2 Composite Spray™ Technology Related Assembly Products/Processes Surface Cleaning Thermal Vacuum Bakeout Solvent Extraction Adhesive Bonding, Surface Modification and Coating Select Industry Testing Standards ASTM E 595 References CO2 Processing Application Note AN1002 © CleanLogix All Rights Reserved 1. “Effect of Sterilization on the Mechanical Properties of Silicone Rubbers”, Saint-Gobain Performance Plastics, Northboro R&D Center 2. ASTM E 595 Outgas Test Reports (Silicone Cable Extraction), Pacific Testing Laboratories, Valencia, CA, Customer/Application Confidential 3. ASTM E 595-93, Standard Test Method for Total Mass Loss and Collected Volatile Condensable Materials from Outgassing in a Vacuum Environment 4. “Peroxide or Platinum? Cure System Considerations for Silicone Tubing Applications”, Dow Corning Healthcare 5. “Anatomy of an Ethylene oxide Sterilization Process”, Technical Tip #10, Steris Isomedix Services 6. “The Leachable Challenge in Polymers used for Pharmaceutical Applications”, Rubber World, Nov 2008. Keywords Silicone Rubber, TVB, Outgas, TML, CVCM, WVR, ASTM E 595 CleanLogix Application Note AN1002 Another clean idea… Think Clean. U.S. Sales and Applications R&D Group: 27636 N. Ave. Scott Unit C Valencia, California 91355 (661) 257-7667 Asia Manufacturing and Sales Office: CleanLogix Asia Pte. Ltd. No. 2 Pioneer Sector 1 Singapore, 628414 www.cleanlogix.com Cleanlogix LLC Do not reproduce this document in whole or part. Centrifugal CO2, CO2 Composite Spray, and CO2 Plasma Blast are Trademarks of CleanLogix LLC All Rights Reserved Patented and Patents-Pending Cleanlogix Application Note AN1002 Surface Prep of Silicone Rubbers.PDF