IMMUNOLOGY
Objectives: The objective of this course is to learn about the structural features of the components of the immune system as well as their functions, but the primary emphasis of this course will be on the mechanisms involved in immune system development and responsiveness. The major experiments that allowed the elucidation of these mechanistic features will be featured to help understand how immunologists think and work.
Content: Immunity. Types of immunity. Subject and immunology tasks. History of development of immunology. Structure and the functional organization of immune system. Antigenes. Chemical nature of antigenes. Full and incomplete antigenes. Main properties of antigenes. Types of specificity. Penetration into an organism and elimination way. Mechanisms of congenital immunity. Primary recognition of antigenes. Patterns and Toll receptors. Phagocytose. B-cellular link of immunity. T-cellular link of immunity. System of cytokines. Interferon. Growth factors. Properties of molecules. Variety of receptors and reception mechanism.
Complement system. Biological functions. Mechanisms of activation of system of a complement. Receptors. Negative immunoregulation. Apoptoz of lymphocytes.
Antineoplastic immunity. Tumoral antigenes. Immune response to antigenes of tumors.
Ontogenese and phylogenese of immune system.
Teaching and learning methods: Lectures, laboratory demonstrations, laboratory work, interactive forms.
ECTS Credits: 3
Assessment: Homeworks, quizzes, examination, group work.