H H annual report 2007 eroes and ope Heroes and Hope... In the fight against tuberous sclerosis complex (TSC), heroes and hope abound, both in small and large ways. The Tuberous Sclerosis Alliance is dedicated to finding a cure for tuberous sclerosis complex, while improving the lives of those affected. Heroes are found across the country, from the families caring for a loved one with TSC on a daily basis to champions for our cause who help increase awareness or raise funds on our behalf to scientists working tirelessly to find better treatments and a cure to healthcare professionals and physicians providing compassionate care. Hope focuses on the future—a world in which no one has to endure the devastating effects of tuberous sclerosis complex. Throughout 2007, the Tuberous Sclerosis Alliance’s heroes helped give hope to thousands as the organization moved forward on several fronts. Four of these special heroes were named TS Alliance Volunteers of the Year: Chris Hawkey, Susan Jorski, Mark Martin and Maureen Reyes, and a special care provider—Dr. David Franz—earned the prestigious Manual R. Gomez Award. Tuberous sclerosis complex (TSC) is a devastating multi-system disorder that causes tumors to form in various organs, primarily the brain, eyes, heart, kidneys, liver, skin and lungs. TSC is a leading genetic cause of epilepsy and autism. More than 50,000 Americans suffer from TSC. Currently there is no cure. Medicine and Research I 2 dentifying better treatments for TSC and ultimately finding a cure are two of the most important goals for the TS Alliance. Therefore, the organization invests heavily in projects that work toward achieving those aspirations. In 2007, the TS Alliance spent a total of $1.1 million on research projects, including the TSC Natural History Database and grant awards. Highlights include: TSC Natural History Database Project One of the puzzling and devastating things about TSC is that it affects every single person differently. Until now, there has been no way to document how TSC progresses over a lifetime, or if there are specific correlations between TSC gene mutations and how it impacts a person’s health. During the past three years, the TS Alliance has been developing a TSC Natural History Database, which is intended to answer some of those questions. • The Minnesota Epilepsy Group, PA (Michael Frost, M.D., St. Paul, MN) and Texas Scottish Rite Hospital for Children (Steven Sparagana, M.D., Dallas, TX) completed the pilot phase and the Steering Committee approved database revisions • Applications approved for Phase 2 sites to begin enrolling in Fall 2007: • Josiane LaJoie, M.D. New York University, New York, NY • Elizabeth Thiele, M.D., Ph.D. Massachusetts General Hospital, Boston, MA • William McClintock, M.D. National Children’s/Metro D.C. Area • Michael Kohrman, M.D. University of Chicago, Chicago, IL • Candy Brown, M.D. Oakland Children’s Hospital, Oakland, CA • Joyce Wu, M.D. and Susan Koh, M.D. University of California, Los Angeles TS Alliance Research Grants Program The following grants were approved for funding to begin July 1, 2006: • Linda DiBella, Ph.D. Sponsor: Zhaoxia Sun, Ph.D. Yale University, New Haven, CT Investigating a Link Between the Cilium and the TSC/mTOR Pathway Postdoctoral Fellowship Award • Cheryl Doughty, Ph.D. Sponsor: David Kwiatkowski, M.D., Ph.D. Brigham & Women’s Hospital, Boston, MA Investigation of TSC2 Missense Mutations Postdoctoral Fellowship Award • Kevin Ess, M.D., Ph.D. Vanderbilt University, Nashville, TN Role of the Tuberin GAP Domain in Neural Progenitor Cells Junior Investigator Award • Arnold Kristoff, M.D. McGill University, Montreal, Quebec, Canada mTOR-containing Protein Complexes in the Pathogenesis of Tuberous Sclerosis NIH Grant Award, Co-Funded by the National Cancer Institute, National Institutes of Health and the TS Alliance • Shao-Jun Tang, Ph.D. University of California, Irvine, CA Roles of TSC2 in Regulation of Dendritic Protein Synthesis and Synaptic Plasticity Junior Investigator Award • Michael Wong, M.D., Ph.D. Washington University, St. Louis, MO Rational Therapy for Neurological Manifestations in a Mouse Model of TSC Senior Investigator Award PKD/TSC Joint Initiative • Seven applications were received and reviewed for a new joint initiative with the PKD Foundation • Two grant applications were co-funded by the TS Alliance and the PKD Foundation, and one grant was co-funded by the Tuberous Sclerosis Association in the U.K. and the PKD Foundation. PKD/TSC Joint Initiative (cont.) These grants were awarded to: • Elizabeth Petri Henske, M.D. Fox Chase Cancer Center, Philadelphia, PA Roles of Tuberin (TSC2) and Rheb in Cystic Kidney Disease PKD/TSC Research Award co-funded by the TS Alliance and the PKD Foundation • Cheryl Walker, Ph.D. M.D. Anderson Cancer Center, University of Texas, Smithville, TX C-SRC Regulation of the Functional PKD-1 TSC2 Interaction PKD/TSC Research Award co-funded by the TS Alliance and the PKD Foundation • Jeremy Cheadle, Ph.D. University of Cardiff, Cardiff, U.K. Investigating the Relationship Between Tuberous Sclerosis and PKD Using Mouse Models PKD/TSC Research Award co-funded by the Tuberous Sclerosis Association, U.K., and the PKD Foundation TSC Clinics • Five TSC Clinic Fund Development Awards were provided to: • E. Martina Bebin, M.D. University of Birmingham, Birmingham, AL • Ajay Gupta, M.D. Cleveland Clinic, Cleveland, OH • Susan Koh, M.D. and Joyce Wu, M.D. University of California, Los Angeles • Paul Levisohn, M.D. University of Colorado, Denver, CO • Hope Northrup, M.D. University of Texas, Houston, TX • Two new TSC Clinics opened in 2007: The Children’s Hospital in Denver, CO (Paul Levisohn, M.D.) and University of Alabama in Birmingham, AL (E. Martina Bebin, M.D. and Bruce Korf, M.D., Ph.D.,Co-Directors). • The TS Alliance sponsored a breakfast meeting for TSC Clinic Directors and Coordinators in conjunction with the American Epilepsy Society meeting in San Diego in early December 2006. • The TS Alliance put the TSC Clinic Committee in place with the following members: • Steve Ashwal, M.D. Loma Linda University, Loma Linda, CA • Martina Bebin, M.D. University of Alabama,Birmingham, Birmingham, AL • Peter Crino, M.D., Ph.D. University of Pennsylvania, Philadelphia, PA • Michael Duchowny, M.D. Miami Children’s Hospital, Miami, FL • David Dunn, M.D. Indiana University, Indianapolis, IN • David Franz, M.D. Cincinnati Children’s Hospital, Cincinnati, OH • Elizabeth Thiele, M.D., Ph.D. Massachusetts General Hospital, Boston, MA Conferences and Workshops • The TS Alliance co-sponsored and participated in the NINDS-funded conference on “Shared Neurobiology of Autism and Related Disorders” in Los Angeles, CA in June 2007 • The TS Alliance participated on the Steering Committee of the “Curing Epilepsy” conference held at the National Institutes of Health in March 2007, and served as a co-sponsor for the conference. April Cooper, parent of twin daughters with TSC, was one of the speakers who gave a presentation on the impact of epilepsy on individuals’ lives. • Vicky Whittemore, Ph.D. attended and gave a presentation on the TSC Natural History Database at the TSC Conference in Rome, Italy on May 26, 2007. • The TS Alliance formed a Conference Organizing Committee in July 2006 to coordinate the International TSC Conference: “Tuberous Sclerosis Complex: From Genes to New Therapeutics” to be held in Annapolis, MD Professional Education • David Kwiatkowski, M.D., Ph.D., Elizabeth Thiele, M.D., Ph.D. and Vicky Whittemore, Ph.D. have agreed to work with Wiley Press to edit and David Neal Franz, M.D., a pediatric neurologist and TSC Clinic Director at Children’s Hospital Medical Center in Cincinnati, OH received the Manuel R. Gomez Award in July 2006. He has had an interest in TSC for 14 years. The TSC Clinic at Cincinnati Children's Hospital Medical Center is one of the largest clinics in the world, which currently follows more than 400 children and adults with TSC, helping assist in all aspects of their medical care, and paving the way for TSC clinical trials using mTOR inhibitors. publish the 4th Edition of the book Tuberous Sclerosis Complex • The TS Alliance provided an exhibit with educational materials at three meetings in FY07: • American Epilepsy Society annual meeting in San Diego, CA in December 2006 • Frances Jensen, M.D. moderated the Investigator’s Workshop on TSC at the AES meeting. Speakers: Peter Crino, M.D., Ph.D., David Kwiatkowski, M.D., Ph.D., Frances Jensen, M.D., and Veronica Alvarez, Ph.D. • Gregory Holmes, M.D. and Vicky Whittemore, Ph.D. coordinated the TSC Special Interest Group (SIG) meeting at the AES meeting. Speakers: Greg Holmes, M.D., Vicky Whittemore, Ph.D., Sarah Spence, M.D., and Elizabeth Thiele, M.D., Ph.D. • The TS Alliance was a co-sponsor of the Hoyer Lecture presented by Dan Lowenstein, M.D., and also coordinated the poster presentation highlighting individuals with epilepsy • The TS Alliance participated in the Vision 2020 meeting with other non-profit organizations at the AES meeting • BIO Annual meeting in Boston, MA in May 2007 • American Thoracic Society International Meeting in San Francisco, CA in May 2007 3 Community Outreach T he TS Alliance reaches out across the country through our vibrant Community Alliance program, now numbering 35 strong. Community Alliances are like “chapters,” providing local contacts, information, support and fundraising. In 2007: • Expanded Community Alliances from 25 to 35 local branches. • Meet the experts Sessions held in the following locations: • Atlanta – October 2006, Mark Mausner, M.D., focusing on skin manifestations in TSC • Pittsburgh – October 2006, Mustafa Sahin, M.D., Ph.D., and Deborah Holder, M.D., in conjunction with the Child Neurology meeting, focusing on seizure types and treatment options • Albany – October 2006, Mustafa Sahin, M.D., Ph.D., focusing on seizure types and treatments • San Diego – December 2006, in conjunction with the American Epilepsy Society meeting, Elizabeth Thiele, M.D., Ph.D., gave a research update and the following physicians participated in a Q&A session: Orrin Devinsky, M.D., Deanna Dickens, M.D., Kevin Ess, M.D., Ph.D., Michael Frost, M.D., Ajay Gupta, M.D., Susan Koh, M.D., Steven Sparagana, M.D., and Howard Weiner, M.D. • Atlanta – April 2007, Elizabeth Thiele, M.D., Ph.D., focusing on neurological aspects of TSC and treatment options • Ohio – April 2007, Sandy Dabora, M.D., Ph.D., David Kwiatkowski, M.D., Ph.D., Dr. and Cheryl Walker, Ph.D., discussing lung involvement, treatment options and an update on clinical trials • Dallas and Houston - October 2007, John Bissler, M.D., focusing on renal manifestations, treatment options and an update on clinical trials • 65 educational seminars, support meetings and community gatherings held by 35 Community Alliances and community groups across the country. • Implemented four Outreach Campaigns to family practitioners, epileptologists, Congress, Churches and Community Support Organizations. • Continued to celebrate October as Volunteer Appreciation Month and honored the 2006 Volunteers of the Year at a special appreciation dinner held in March in Washington, DC. Susan Jorski serves as chair of the TS Alliance of the Pacific Northwest and was honored for her long-time commitment to helping others with TSC in her area, not only offering support and information but also tirelessly raising funds through events such as the Step Forward to Cure TSC walkathons. As one nominator said, “Susan has touched the lives of each and every person she’s met in the TSC community.” 4 Community Alliance Leadership TS Alliance of Arizona Debora Moritz, Chair TS Alliance of the Heartland Cindy and Ryan Blackard, Chairs TS Alliance of Atlanta/North Georgia Dee Triemer, Chair TS Alliance of Houston Lucy Martinez, Chair TS Alliance of the Carolinas Amy Quintana, Chair TS Alliance of Indiana Christine Davis, Chair Roma Hinton, Vice Chair TS Alliance of Connecticut Jennifer Waldron, Chair TS Alliance of the Dallas/Ft. Worth Area Maria Cole, Co-Chair Tricia Bodnar, Co-Chair TS Alliance of the Delaware/Lehigh Valley Shelley Richards, Co-Chair Cindy Richards, Co-Chair Liz Saadoun, Co-Chair TS Alliance of Intermountain West Julie Fleming, Chair Valarie Rhead, Vice chair TS Alliance of Metro DC Julie Blum, Chair TS Alliance of Middle Tennessee Sharon Lackey, Chair TS Alliance of Florida Barbara Alvarez, Co-Chair Deb Yohn, Co-Chair TS Alliance of Michigan Treasa Bolger, Chair Matt Bolger, Vice Chair Sharon Arndt, Vice Chair TS Alliance of the Delta Region Carla Shrider, Co-Chair, Samantha Glass, Co- Chair TS Alliance of Nevada Kathleen Kingston, Chair Mary Ann Weidner, Co-Chair TS Alliance of Greater Alabama Carole Pitard, Co-Chair Shirley McAfee, Co-Chair Donna Ross, Vice Chair TS Alliance of New England Karin Sullivan, Chair Jeffrey Hargreaves, Vice Chair TS Alliance of Greater Chicago Jay and Lisa Smiley, Co-Chairs TS Alliance of Greater Kansas City Laura Kozisek, Co-Chair Lisa Hart, Co-Chair Amy Dublinske, Co-Chair TS Alliance of Ohio Jim and Nancy Weir, Co-Chairs Carl and Lola Centeno, Co-Vice Chairs TS Online Community Alliance Maureen Reyes, Chair Beth Tinlin, Vice Chair TS Alliance of the Pacific Northwest Susan Jorski, Chair Lisa Bennett, Vice Chair TS Alliance of the Rocky Mountain Region Dana Holinka, Chair TS Alliance of Southern California April Cooper, Co-Chair Christy Hobart, Co-Chair Julia K. Cohen, Vice-Chair TS Alliance of Sacramento California Kerry Parsons, Chair TS Alliance of St. Louis Rene Friedel, Co-Chair Dave Henke, Co-Chair TS Alliance of the Upper Midwest Jim Hable, Co-Chair Missy Anderson, Co-Chair TS Alliance of New Jersey Sherrie and Dennis Busel, Co-Chairs TS Alliance of Virginia Linda Wolters, Chair Adrianne Cohen, Vice Chair TS Alliance of the New York Metro Area Peggy and Tommy Lindsey, Co-Chairs Francine Ostrow, Co-Chair TS Alliance of Western Pennsylvania Mike Seman, Co-Chair LuAnn Keppel, Co-Chair TS Alliance of Northern California Dena W. Mitchell, Chair TS Alliance of Wisconsin Kristin Champagne, Chair TS Alliance of the Hawaii Tricia Gerum, Chair 5 Community Support P roviding support is one cornerstone of our mission to “improve the lives of those affected” by TSC. The TS Alliance and its volunteers fulfill this goal by providing peer-to-peer contact in our Matching Program and Support Network, offering vibrant online discussion groups, and operating a toll-free number with access to a fulltime Director of Outreach and Advocacy. • 299 individuals in 47 states and Puerto Rico serve as Support Network volunteers offering a hand of support to others in their local area. • 169 individuals in 47 states provide peer support for those seeking information on a particular topic area or manifestation of TSC • 650 individuals participate in our online community support for parents/caregivers, adult with TSC, grandparents and teens. • In communities across the country, 2,599 individuals stood beside us as we Stepped Forward to Cure TSC. • Hundreds of free information packets and publications mailed upon request, including the updated 2007 version of “Introduction to TSC” and a new booklet called “In Their Own Words: Personal Journeys with TSC.” • The TS Alliance website continues to be a major resource, garnering an average of 1 million hits monthly. Maureen Reyes is a long-time leader of the TS Alliance’s online discussion groups, which offer thousands of people around the world immediate access to others affected by TSC. Maureen is the “mother of our online community. When someone reaches out for helping hand or a cyber hug, you will certainly find Maureen right there, anytime, day or night.” 6 Government Advocacy T he TS Alliance and its constituents work tirelessly to increase Federal funding for TSC research in a variety of ways, including personal visits to Congressional members, letter and email campaigns, and meetings with Federal agencies. In 2007, advocacy efforts helped secure $4 million in fiscal year 2008 for the Tuberous Sclerosis Complex Research Program at the Department of Defense. Highlights include: • 215 constituent visits to Congressional offices during March 2007 • 54 Representatives signed the House Dear Colleague letter • 19 Senators signed a Senate Dear Colleague letter • Directive language secured for the Centers for Disease Control and seven institutes at the National Institutes of Health in the fiscal year 2008 Labor-Health and Human ServicesEducation Appropriations Act. Mark Martin and his son both have TSC, leading Mark to be a leader in seeking increased federal funding for TSC research by advocating on Capital Hill, as well as reaching out to other adults with the disease. “Mark brings a unique perspective as an adult and parent and as such, he understands the needs, desires and frustrations of everyone with TSC.” 7 Fund Development P 8 eople from across the United States help the TS Alliance raise much-needed funds by organizing events ranging from garage sales to dinners to walkathons to star-studded comedy nights. Others raise money on their own through letter writing or, like Chris Hawkey, donating proceeds from his CD. No matter the amount, these efforts help our organization provide services and programs to all those affected by TSC and also increase awareness of our cause. For 2007, special events raised more than $2 million for the TS Alliance. 2007 highlights include: • With the heartfelt and loyal support of Andy and Mary Bott, The Original Food & Wine Event celebrated its 15th and final year, raising an astonishing $818,000 over the years. • Champions of our cause nationwide participated in 25 Step Forward to Cure TSC Walkathons raising $837,127 in the hope of a cure. • Two spectacular events were held in New York this past year with the help of our heroes from the New York Metro Area and New Jersey. Giant Steps to the Cure, a casual sports themed gala, counted among its supporters honorary chair Tiki Barber, host Julianne Moore, Chris Hawkey Power Play and a “team” of sports legends and raised more than $325,000. The event honored long-time supporters Elizabeth Buchsbaum and Francine Ostrow, Marc and Marla Shapses and Dr. Howard Weiner. In November, the TS Alliance hosted an event in conjunction with Julianne Moore’s Broadway debut in The Vertical Hour. • John Roberts, CNN Morning Anchor, generously loaned his support to the DC Food & Wine Tasting as emcee and honorary chair. John’s close friends have a grandson with TSC and his meaningful support was in their honor. • Julianne Moore selected the TS Alliance as her charity of choice for the Cartier LOVE Day with proceeds from the sale of their lavender LOVE Day bracelets going to the TS Alliance. • Our signature event, Comedy for a Cure, continued its successful run in Hollywood, honoring Patricia Heaton as well as House and its creator David Shore. Teri Hatcher served as honorary chair and performers Ray Romano, Jeff Garland and Sherri Shepherd added star power to the evening. To date, Comedy for a Cure Hollywood has raised nearly $1 million. Comedy for a Cure Boston enjoyed its second successful year with Jimmy Dunn once again loaning his support as honorary chair and Tony V. jumping in as auctioneer as well as performer. Events Raising More Than $10,000 Step Forward to Cure TSC Walkathons and Runs Arizona – Debora Moritz Atlanta – Dee Triemer and Reiko Donato Cleveland – Frank and Elaine Gritti Connecticut – Jennifer Waldron, Julie Gribbins, Melissa Sullivan and Janet Verney Corpus Christi – Carol Valdez Greater Chicago – Jenny, Jay and Lisa Smiley Dallas/Ft. Worth – Mandy and Scott Striegel Dayton – Tami Ball Heartland – Susan Ballantyne Houston – Taska Fields and Lucy Martinez Intermountain West – Julie Fleming and Valarie Rhead Las Vegas – Kathleen Kingston and Mary Ann Weidner Metro DC – Nathalie Simoneau Michigan – Treasa and Matt Bolger Milwaukee – Pam Sztukowski New England – Tom and Sharon Gwinn Rocky Mountain – Jim Lynch, Cindy Lynch Seattle – Kay Rawlings St. Louis – Jaime Schmitt Southern California – Milly Augustine Tuscaloosa – Jan Hall Upper Midwest – Sherri Trapp and Maria Gibbons Valley Forge – Shelly Richards and Cindy Richards Western Pennsylvania – Shelley Blackwood and Lori Shoup Chris Hawkey has been a long-time TS Alliance supporter and constantly shows his commitment to raising awareness of the disorder as well as donating all profits from his CD, The Pursuit, to the TS Alliance. “Chris is truly dedicated to our cause even though he is not personally affected by TSC...nothing makes him happier than to see a child with TSC smile, move and if possible, dance to his music.” Tournaments for TSC Champions Dave Bauer Memorial Golf Classic – Virginia Bauer Don Tech Annual Golf Tournament – Ken and Shonnie Johnson Emmory Regan Shapses Golf Classic – Marc and Marla Shapses Kenvo Open – Mark E. Votta Kylie’s Hope – Neil and Maria Gibbons, Kelly Gibbons Orange County Golf Classic – April Cooper, Pat Rolfes and the Orange County Golf Committee TS Charity Golf Scramble – Doug and Linda Loftus Wentworth Charities Golf Classic – Tom and Sharon Gwinn Other Major Events 21st Annual Shrub Sale – Bert and Sue Goodrich 6th Annual Comedy for a Cure (Hollywood) – Christy Hobart, Henry Shapiro, Chris Sheffield, Tonya Toone and the Comedy for a Cure Committee A Gala at the Ritz – Pat Schmutte and Diane Munneke Chicago Family Fun Day – George and Becky Wendel Comedy for a Cure Boston – Jeffrey Hargreaves and Jane Ulwick Crashing for a Cure – Joe and Abby Kopf DC Food & Wine Tasting – Julie Blum, John Poutasse, John Richards and the TS Alliance of Metro DC Giant Steps to the Cure – Robin and Jeremy Krantz, Tommy and Peggy Lindsey, and the Gala Committee The Original Food & Wine Event – Andy and Mary Bott The Vertical Hour Reception – Julianne Moore Annual Fund—Major Donors Fiscal Year 2007: July 1, 2006 - June 30, 2007 PRESIDENT’S CIRCLE ($100,000 - $499,999) Julianne Moore and Bart Freundlich Marc, Marla and Emmory Shapses (ERS Charitable Foundation) Harold Simmons Foundation Tuberous Sclerosis Alliance Endowment Fund BENEFACTOR ($50,000 - $99,999) Cartier Estate of Craig Lewis National Institutes of Health Brian and Sandra O’Brien The University of Texas Southwestern Susan Watts William E. and Kristina Watts Wentworth Charities Organization SPONSOR ($20,000 - $49,999) The Abington Foundation Craig and Cindy Cunningham (C&C Market Research) Cyberonics, Inc. Eldorado Lions Club Chris Hawkey LaCoste Levit Family Foundation The National Basketball Association and The Women’s National Basketball Association Ovation Pharmaceuticals, Inc. Red Bull North America, Inc. The Rothberg Institute for Childhood Diseases State of New York Strategic Group UCB Pharma Inc. Variety PROTECTOR ($10,000 - $19,999) Maurice Amado Foundation Athena Diagnostics, Inc. David and Linda Baird CIBC World Markets Corporation Cities 97 Sampler Kimberly Corbett Creative Agency Group E*Trade Financial Corporation Family and Children’s Service General Mills, Inc. Henick-Lane, Inc. The Gertrude and Philip Hoffman Philanthropic Fund of the United Jewish Federation Foundation David Hunt and Patricia Heaton The Lauren Krinsky Family James and Jessica Lawler (Glenn N. Howatt Foundation) Love*Live*Laugh Coleen Murphy Foundation Larry and Diane O’Friel PhRMA Studley, Inc. Scott and Susan Taylor (The Winifred M. Gordon Foundation Inc.) David Tepper Charitable Lead Annuity Trust C. Anthony Whittingham DEFENDER ($5000 - $9,999) Taz Anderson Ark Builders LLC Bank of North Georgia Kenneth and Jeanne Bott George and Laura Braunstein Gertrude Brown Eugene Bruns Buffalo Wild Wings Frances W. Burton Foundation Mark and Kelly Carroll Christensen Ehret, LLP Scott Clarkson (Glacier Design Systems, Inc.) Will and Kay Cooper (WNC & Associates, Inc.) Carl and Charlene Corso Culpepper Development, Inc. Pamela Edstrom Moise and Carol Emquies (Mo Industries) Joseph and Hilary Feshbach Mark and Judy Fox Pavan and Anna Gattani Joseph and Mary Goodman Carla Heck 9 Harold Hofer (HFF Securities L.P.) Ken and Shonnie Johnson The Josephs Foundation Kenvo Foundation Lydia Lewycky Herbert and Sheila Marton Massachusetts General Hospital (Partners Healthcare System) Cecelia McCarton (McCarton Center) James and Cindy Megginson David and Jan Mintz James and Debora Moritz (Cake Arts, Inc.) John Motzel Jeffrey and Vicki Sprinkle (MP Equipment Company) Jerrill and Heidi Sprinkle (MP Equipment Company) Philip and Tammy Murphy Donna Nichols Albert and Jeanne Nigro Novartis Institutes for Biomedical Research Inc. NY Epilepsy & Neurology PLLC Peter Ostrow Don and Susan Petty Thomas A Plein Foundation, LTD Robert Rapaport John and Nancy Richards Bonnie and Jonathan Rothberg & Family C&M Schnurmacher Foundation, Inc. Shamrock Materials Sterling Ethanol Steven and Gayle Temkin Tigi Linea, LLP Frederick and Marylou Tramutola Twentieth Century Fox Film Corporation Wells Fargo Bank Joe White Peter and Margaret Wilby Kevin and Sarah Wright (Indigo Contracting, LLC) Hilda and Phyllis Wulach ADVOCATE ($1000 - $4,999) 4th and Walnut Centre, LLC A & D Building Maintenance, Inc. Abbott Northwestern Hospital of Allina Hospitals and Clinics 10 Sharon Abramson Howell and Madeline Adams Marion and Ann Adams Trey and Lucy Albers All Environmental American Building Maintenance Company Anthony Garden Boutique Ltd. Marisa Antonini Foundation Apache Corporation Pat and Jennifer Rolfes (Aquabrew) Ernest and Maryann Arias Harold and Jeanne Aronson Peter and Deborah Aronson Asphalt Milling Services Inc. Auto Inspection Services, Inc. Michael Bill Avner Memorial Foundation of the Pittsburgh Foundation Back Bay Energy Company Baltimore American Mortgage Corp Dennis and Sharon Barchuk J.D. Bartel Virginia Bauer Michael and Laura Beber Bruce and Laurinda Berger Bipartisan Policy Center Michael and Shelley Blackwood William and Thelma Blood Blumenfeld, Kaplan, and Sandweiss, PC Melvin and Roseanne Boldt Borg Produce Sales Brad’s Roofing Co., Inc. Blair Brickman Briggsville United Methodist Memorial Fund Cheryl Bright Brooks Sports Inc. Brookview Financial Alan and Rita Buchsbaum Andrew and Elizabeth Buchsbaum Gerald and Suzanne Burt Business Knowledge Services, Inc. Robert and Sarah Butler Butler Co PA Chapter of Thrivent Financial for Lutherans Kelly Byrne Jon Cantor Kari Luther Carlson Carpet Concepts Casco Contractors, Inc. Cavarocchi Ruscio Dennis Associates, LLC Centers for Disease Control & Prevention Champion Chevrolet Champions Pipe & Supply Charles Schwab Chicago Tag Label Chicago Title Insurance Company Jonathan and Susan Child S. William and Sue Clark Cleveland Clinic Clothes Off Our Backs Coastal Title Agency Cobb EMC John and Jane Collins Wayne and Roberta Colmer Compass Insurance Agency, Inc. Alfred and April Cooper Wilfred and Jennifer Cooper Corpus Christi Jaycees Cox, Castle & Nicholson, LLP James and Leslie Craige Robert and Elizabeth Cullins George and Elizabeth Cultraro Currie Motors Leonard Davis Enterprises Cornelius DenHarder DeVito Associates LLC Michael and Rita DiDomenico (DiDomenico Packaging, Co., Inc.) Digicomm International, Inc. Gregory Dillion Michael and Doreen Discavage Disney Worlwide Services, Inc. Divine Enterprises Chris Dolan Tom Dolan Richard and Reiko Donato Dan and Shelia Dunn Harry and Chantal Dussouchaud-Dolman Jeffrey and Mary Cruz (E.E. Cruz and Company Inc.) Allyson Edwards Richard and Athena Eitel Terry and Nancy Elling EMCOR Service John and Kathleen Ewonus Feitler Family Fund Linda Feldmann Melody Fennel FIALA, LLC First Team Real Estate Robert and Cristina Fitzgerald Thomas and Susan Flanagan William and Jody Flynn Janet Fogarty Kelley William and Anita Ford Michael and Leslie Fox David and Michele Franz Freight Force, Inc. Bernie Friedman Gerald and Irene Friedman Peter Gaboriault Frank and Laura Gallagher (Courtney Leigh Small Steps, Inc.) Garland Restoration, Inc. William and Francine Gates Neal Gehring Gerber/Taylor Management Company Ralph Gibbon Lisa Gill Global Allies, LLC Global Impact GlobalSantaFe Thomas Grace Charles and Suzanne Graham Robert and Nancy Graham Robert and Jen Grunbeck (The Grunbeck Family Foundation) Patricia Haas J.B. and Jan Hamilton Donald and Natalie Handelman William Hanks Gregory and Sarita Hanley Dale and Stephen Harburg Jeffrey and Lisa Hargreaves Teri Hatcher Ralph Hattenbach Timothy Heffernan Rory Held Joseph and Susan Helfgot Elizabeth Henske Timothy and Janet Hill G. Dana and Vicki Hobart James and Amy Hobbs Jeffrey and Laura Hollingsworth Holme Roberts & Owen LLP Dan and Kathleen Holthaus Shaun and Tracey Hutchinson Ed and Sandra Hyde-Swanson Mark Hyman and Sheryl Neuman Scott Isander Ismael Leyva Architects, P.C. J & H Asset Property Mgmt., Inc. Wendell and Marie Jansseen JD Rush Corporation JMI Bruce and Georgia Johnson R. Scott and Emily Johnson Johnson Capital Matt and Susan Jorski Jay Kaiser Arnold and Carol Kamm Kanaly Trust Co Robert and Cassie Kelle Robert Kendrick Kent and Sandra Ketchum Keurig Premium Coffee Systems Craig and Sally Kieny Paul and Leslie Kiernan Chick Knight Kenneth and Beth Kocher Jeremy and Robin Krantz (Smith & Krantz LLP) Ladies of Unico - Kearny, NJ Chapter Peter LaForte and Judy Ratner Henry Lambert Thomas and Eileen Landry Jeffry and Lynn Lapin Vincent Lara and Megan Johnson Laticrete International, Inc. Roger and Laura Lavan Louis and Laurie Lebedin Richard Lee Leesville Auto Mike Leiderman Jean Leonard William and Michele Leonard Steven and Charla Lerman Leventhal Senter & Lerman PLLC George and Cleo Liapis Thomas and Margaret Lindsey Greg Linsin and Julie Blum Lionhead Group Love Ride Foundation Lucas Development Corp. Cindy Lynch (JPL Inc.) James Lynch (JPL Inc.) James D. Lynch M & M Sales & Service, Inc. James and Andrea Maginn Kyle and Barbara Magnusson Christine Mahoney Paul Manton MARMC Transportation Henry Marraffa Brent Marsh Marsh Affinity Practice Abe and Celia Mastbaum Theodore and Peggy Mastroianni Mark and Karen Mausner (Mausner Plastic Surgery Center) Robert and Margery McBride Charles and Christina McCraw Terrance and Laura McLaughlin Robin Meltvedt Mesa Marketing & Sales, Inc. Metal Clad LLC Michael and Carol Michael Carl and Lucille Miles 11 Roger and Melissa Miles Mirage Sports Bar Moffatt & Nichol Philip and Jane Molstre Monarch Beverage, Inc. The Money Box Tom and Wendy Morton Ted Moudis Stan Mounce Muhlenberg Foundation Kevin and Stefanie Murray James and Margot Mustich Ronald and Julie Nemeth Richard and Sharon Nicely John and Carol Nicholson Norgren Family Fund North Coast Jaw Center LLC Novara Clothing O’Melveny & Myers LLP Oshkosh Community Foundation Joseph and Francine Ostrow Robert and Stacey Otte Anne Otterson John R. 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Swimm Artworks Synergy Annie Szilagyi Taco Del Mar Brook Tart Stephen and Winifred Tart Ron and Nancy Taylor H.D. and Linda Tewis Texas Scottish Rite Hospital for Children Larry and Jerilynn Thomas Rob and Loni Thurston David and Charlene Torchia Richard and Susan Trester Trico Development, Inc. Tririga Kent and Patricia Troup United Healthcare Universal Protection Service University of Nevada, Las Vegas US Bank Richard Van Lunen Charitable Foundation Andrew Van Tassel Teresa Vautier Grace Vincent Vinmar International, LTD Donna Vitale Walter and Jean Voelkerding Samuel and Jo Ann Wacht (Samuel Wacht Associates) Philip and Cindy Wales Walgreens Wal-Mart Stores, Inc. Philip Walsh The Warren Fund Watkins, Meegan, Drury & Company, LLC Watt Family Properties, Inc. Dale and Lisa Weaver Cherles Weddle Rod and Marie Weeks John Werner Jack and Jeannie Whitaker Jack Whitaker Timothy Whitaker Clifford and Deborah White Robert and Lynn Wilson WM Harold Jewelers Michael and Cecilia Wong Alyce Woodward (Gerald Oppenheimer Family Foundation) Stanley and Joan Worton Joseph and Deborah Yohn Pierluigi and Enrica Zappacosta Howard Zimmerman CHAMPION ($500 - $999) Jon Aber Accurate Marine Environmental, Inc. John Adams and Nancy Ory Advanced Underground, Inc. Thomas and Lisa Aldridge Alexian Brother’s Health System Farid and Faranza Ali All Ink, Inc. Allscope Services, Inc. Amalfi American Auto Body of Osseo, Inc. Amica Companies Foundation David and Joyce Anderson Tracey Anderson Nicole Andrews Joan Andros Arapahoe Park Pediatrics Harry Archung Arizona Panoramic Landscaping, LLC Christine Arnold Sam and Elizabeth Aronow Haldon and Sandra Ashton Ashton Land Surveyor, Inc. Michael and Mary Aycox Ron and Irene Ayotte R. Tom and Jean Bailey Sharyar and Sharon Baradaran Charles and Francesca Bardes Keith Barfield B.L. and L.J. Barness Norman Bauman Thomas and Elizabeth Beattie Larry and Denise Beckerle Lawrence Begin Glenn and Michele Bellomy Joshua and Susan Bennett Nick and Sherrie Berchin David and Maggie Berg Tom and Elizabeth Berra Robert and Kelly Best Bradley and Leslie Blake Julie Blanchard John and Jennifer Blickenstaff William and Michelle Blood Howard and Betty Blum James and April Blum Boca Raton Community Hospital Charlie and Michele Bock Gerald and Emily Boleen James and Molly Bolger Boosters For Perciak Robert and Lori Borrazzo Luciano Bortone Andrew and Mary Bott Joe and Donna Bryant Robert Burmeister Plato Cacheris David Camilleri Robert and Susan Campbell Canton Firefighters #2289 Capital Services, Inc. Frank and Barbara Capone Joe and Mattie Carrillo Cars 4 Causes CarSpa James and Diane Caserta CDM Trucking, Inc. Bernard and Linda Chalfin Larry and Carol Chapman Chopper’s Rod & Customs Restoration Paul Ciaramitaro Philip Ciarco Dustin and Emily Ciccarelli Richard and Susan Clack Amy Clarke Patricia Cochran Colorado Springs Civitan Club John and Mary Conner Linda Connors Mike and Mary Cook Richard and Barbara Cooper Neil and Jill Cooperstein (Paragraphics, Inc.) CORE Health Care Tonya Couch Erica Courtney Mary Brooke Covel Richard and Amie Cramer Peter Crino Paul and Eileen Curry Terry and Marci Cuthbertson Dairy Queen of Howell Dalio Family Foundation, Inc. Dana Point Cigar & Wine Noble Darrow James Davis and Laura J. Pelco Thomas Davis Roderick and Cindi Davoud Dayton Foundation Depository De La Chapelle Charitable Foundation Trust Ramon DeCastro and Linda Feldmann Tim and Paula DeHaven 13 Jorge and Brenda DeLaHoya David Denefeufville James DePalma Stephen and Julie Des Jardins George Deuble Foundation Bonita DeWoof Joseph and Carla DiBenedetto Peter and Rena Dicce Leonard and Lisa Dick Ross and Mary Dierdorff John and Hilary Domeika Ann Dorman Dan and Jennifer Dotson Douglas Douty DP Gales Thomas and Mariana Duncan Earthcare Recycling Elle Magazine Todd and Teresa Embury EmCentrix, Inc. EnerSys Peter Engelman William and Lisa England Nancy E. Epstein Foundation Brent Erickson and Robin Bousman Faith Manufacturing Company, Inc. Farallon Consulting, LLC Susan Farnsworth Angela Feib Ferrari of Newport Beach Peter and Debra Ferriso FGR Mechanical Alan Fishman Micheal and Jacqueline Flaherty Floorworks Foss Maritime Co. Paul Foster Molly Foulks Andre Francisque James and Jenny Fredrickson Jeffrey Freed Freehold Regional High School District Randy French 14 Mark Fritz Front Range Window & Door Barb and Carole Fryberger Ravi and Padmaja Gampala Daniel and Annette Garfinkel GB Tubulars, Inc. John and Pamela Gendreau Geneva Rock Kathy Geoppinger Andrew and Gail Gershon Gerald and Helen Geyso Onofrio Giannoni Brendan Gibbon Rick and Jennifer Glassman Suzanne Glenn Global Market Insite, Inc. Louis and Tiffani Goff Steven and Shari Goldstein Glen and Amy Grabelsky Michael and Miriam Green David G. Greenstein and Hillary Mandel Frederick and Jennifer Gross Groundmasters Landscape Services, Inc. Jean Guerra Tim and Karen Guest H.E.B. Halliburton Foundation Darwin Hammer Robert and Cindy Hammerquist Hansair Logistics Barbara Harding Andrew Hatupis Howard and Kathie Herdman Hile Controls of Georgia, Inc. Shirley Hill C. Dana Hobart Carol Hobart Torbjorn Hodne Jeffrey and Karen Hoersch Michael and Sarah Hoey Michael and Dawn Hoffman Jim and Jane Hogan Wayne and Peggy Hollis Michael Holloway Michael and Suzanne Hopkins Horizon Kevin and Sandy Huber Donald Huggins Michael Hurley Carl and Cindy Hyman India Palace Restaurant Robin James The Janus Foundation Tanya Jawwaad Sherman and Pauline Jensen Lawrence and Nancy Johnson William and Melissa Joyce James Julian Jay and Deborah Julow Frank & Fay Katlin Family Foundation Kym Karath Frederick and Paula Katz Morton Katz Michael and Wendy Katzman David and Lorraine Keir Richard and Judith Kingman Alison Kirby Kiwanis Club of Marietta Lost Mountain Golden K Barbara Klein Chesterton Knight Michael and Joyce Komson Steve and Laura Kozisek Krantz & Company, Inc. Mathias Kremer Melanie Krinsky Todd and Debi Kronebusch Robert and Cynthia Kupper Barbara Kurnit Peter and Jeannette LaForte Emile LaMadeleine Steven and Marsha Lancaster Martha Lapadakis Lawnco, Inc. 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Ray Rayburn Heather Raymon Realty Service Group Alan Reback Nancy Recchia James and Carey Rehm Remedy Interactive RG Frieght Consultants LTD Boyd and Trudy Rhodes George and Dolores Riley Lucian Rivela River Operations Riverfront Partners, LLC Jason Robbins John and Michele Robertson John and Suzanne Rohrer Paul and Kathy Rolfes Dan and Brenda Rompf Alvin and Lynn Rosen Eric Rosen Jay and Marlene Rosen Michael and Elizabeth Rosen RPM Insurance Agency David Rule P. Baman Rusby and Amanda Wood Fabrice and Liz Saadoun Saint James Episcopal Church Women Thomas Salzer Sam’s Club # 6325 15 Michael and Dawnmarie Saunders Saxby’s Coffee Shop Thomas and Deborah Schaeffer John Schell James Schmidt Ray Schultz Lynne Schwitz Jack and Donna Scott SECOR International Inc.orporated Jerry and Fay Seessel SelectHealth Joe Sensers Sports Grill and Bar Fran Sheff-Mauer Thomas and Kathleen Shelton Thomas and Stephany Sherman William and Marla Sherman Gary and Dona Shockey Gary Shoemaker Architects, PC Seth Short Jeffrey and Karan Siemsen Jay and Lisa Smiley Mike Smith and Pat Hagins Isabel Francis Smith & Ralph Lawrence Smith Foundation Soloway, Goldstein, Silverstein & Co., P.C. Spa Villa Salon Richard Spain Spectrum Health Care Mark Spiegel Spring House Robert and Nadine Sprinkle St. Anthony’s Medical Center Foundation St. Mark Lutheran Church Stark County Women’s Clinic Stealthbits Technologies, Inc. Gayla Steele Michael and Ruth Stoddard David Stortz Melvin and Gilda Strom James and Maureen Sturm Sun Country Heating & Cooling John and Barbara Swanson Robert Swanson 16 Michael Tama Phyllis Tapp Tara/Jordan Management Ltd. Mark and Tracey Tatch Jimmy and Linda Tavis Barbara Taylor Phillip and Susannah Taylor Team Health Inc. Law Offices of David S. Thalheimer Sean and Kelly Thomann Wallace Thomas Mark and Nadine Thorn Time Warner Cable Sheldon Trachtenberg and Caren Mazure Fred and Sherri Trapp Robert and Janet Trout David Tsiang James and Cynthia Tuite Ramana Rao Turlapati Twin City Co-ops Thomas and Kathleen Tylman Alex and Kelli Tzoumas Unilight Universal Aviators Academy Roderick Vanderhoef John and Mary Lou VanSant Joseph and Cynthia Ventura Anthony Venturella Valerie Vetters James and Catherine Wadsworth Cheryl Walker Debbie Wallis Jim and Kathy Walsh Patrick Walsh Troy and Anne Walton Charles R.Warde Foundation John Wasley Watkins Uiberall, PLLC Toby and Sara Webb Roberta White Vicki White Amos and Sondra Wilhelm Wilshire Manufacturing Harold and Linda Wilson Otto and Angela Wilson Sean and Kathryn Wilson Wireless Source Diane and Howard Wohl Family Foundation George and Linda Wolters Brian Woods Melvin and Ann Woods World Sleep Products, Inc. Richard and Lisa Wrench John and Laurel Wrynn Ed Yeats Neil and Beth Yelsey Cece Yorke Christopher and Virginia Yukins Michael and Angela Zarrilli Barbara Zimmerman Seymour and Audrey Zubkoff Minnesota Teen Challenge Academy PATRON ($250 - $499) 17th St. Beauty Center A Perfect Landscape Able Equipment Co. Kristin Abraham Absolute Clean Environments, Inc. Accu-Care Home Nurses, Inc. Acorn Design and Manufacturing Action Carting Environmetal Svc., Inc. Art and Anya Adamo Debbie Adams James and Lee Ann Addison Advanced Radon Mitigation, Inc. Aire Serv David Alberts Erika Albini Ann Alder Mark and Rose Marie Alex Cynthia Alexander Nur and Farah Ali Kristen Aller Amy and James Almendinger Roger and Roger Alwang Steven Ambus Diane Amdur American Bridal Show Company American of Martinsville, Inc. Anchor Environmental, LLC Alex and Maureen Anderson Richard and Kaylene Anderson Gregory and Nancy Annick Jeff Apple Robert and Jeannette Apple Appleseeds Day School Inc. Amy Aquino Aramark Uniform and Career Apparrel Arbor Green, Inc. Dean and Michelle Arndt Gordon and Pauline Arndt Kenneth and C. Arnold Arnold Health Memorial VFW #5151 R. Paul Ashton Lindsay Atwood AU Sable Grove Presbyterian Church C. Russell and Ceil Augenstein Virginia Avvento Chris and Linda Ayers B. C. Holmes Living Trust Kenneth and Lisa Bacco John and Kathryn Baccus James Bandstra and Arlene Achterhof Bank of Choice Colorado Bardi Catering, Inc. Jason and Diane Barnes Robert and Illa Barness Tom and Jane Barnett Brian Barringer Edmund and Mary Bartlett Gaby Baxter Betty and Roger Beathard Ralph and Sheila Beatty E. Martina Bebin Bernard and Evangeline Beem Edward and Gwen Beidman Richard and Merle Beldner J.V. and Sherry Bell Bellabacci Benefits Marketing Association Rick and Carol Bennett Berchin’s A&W Restaurant, LLC Frances Bercier Whitney and Steve Berg Michael and Pearl Bergstein Laurent Bertet Marc and Rachel Bevis Ron and Linda Bexell Tom Binder Fine Art/ Alexander’s World Stanley Black Jim and Heather Blanchard Blue Spruce Landscaping Stephen and Lisa Blumm Matt and Treasa Bolger James and Anne Bolz David and Vibeke Borham Thomas Bowman Tracy and Robert Boyle Ben and Gail Brancel Kevin Brand Andree Braun Willy and Janice Breitschmid Mike Breslow Patti and Joseph Brill-Piscitelli John and Natalie Brockland Robert Brockman Brooklyn Homiside Squad Harry and Karen Broome Brothers Pizza Express, Inc. R. Craig and Kathleen Bryson Howard and Catherine Buck Sally Buckman Dennine Bullard Kevin and Mary Buoy Merle and Joyce Burkheiser Stephen Burrowes Nancy and Eddie Bush Business Capital Edge Butterfield Communications, Inc. Earl and Ida Buys Max and Rita Byrd David and Jannett Caldwell David and Rixey Canfield John and Cathy Carlson Richard and Sally Carp Barry and Sharon Carpenter Thomas and Martha Carper Damon Casatico Jessica and Donald Catino Richard and Janet Caulk Charles James Cayias Ins., Inc. Centaur Building Services, Inc. Centennial Toyota Centria Michael Chen Itzamarie Chevere-Torres Child Neurology Associates, PC Thomas and Kim Christensen Henry and Barbara Christiansen Chubb & Son Stewart and Lisa Cink Vincenzo Cirianni Citizens to Re-elect Terry R. Parke Paula Clark Megan Coalson Wendy Cochran John and Janet Cogbill Marcia Cohen Elaine Coleman Kevin Collier The Commonwealth Foundation, Inc. Complete Packaging Products Michael and Genevieve Conlin Casey Conner Jennie Connery The Consovoy Family Foundation Julie Conway Dulcie Cooley Steve and Christy Cooper Cottage Grove Police Assn. Don Courtney Barry Coutant Cox Auto Trader David R Craig, Attorney at Law Linsi Crain 17 Cheryl and Phillip Cramer Melissa Cronland Katy Cushing Jeffrey and Linda Cwiek Randy and Jennifer Czyzewski Denise D’Adamo David and Margaret Dalva Daniel Hand High School Grant and Bonney Daubenspeck John and Irene Davila Manuel and Maryhelen Davila Bob and Linda Kay Davis Donald and Sherry Davis William and Christine Davis James and Shellee Decker Chris and Robin DeHaven Robert DeHaven Deja Vu, Inc. Ricci Demartino Dave Demeo Richard deNeufville Hui Ling Deng Bruce Denson and Sarah Mizerany Derenthal & Dannhauser LLP James Dibartolo Kathleen and Tim Dills Bennie and Patty Dodd Jesse and Frances Dolinger Albert Domingo Don’s Body Shop John and Dana Doughtie David Draghi Debra Drenth Doreen Driscoll Ross and Vera Ducept Katrin Duevel John and Sylvia Duplantier Amanda and James Dutcher Eaton Corporation Steven and Jill Edwards Morty and Norma Ehrlich Andrew and Connie Elisee Scott and Dixie Elliott 18 Heather Ely Robert Elzie Karen Engleman Enterprise Rent-a-Car Environ International Corporation Episcopal Carmel of Maryland, Inc. Jay and Peggy Erb Alethia Erotas Christine and Dean Estling James and Gerianne Evans Extraordinair Mechanical Inc. Mary Ann Fair Family Resource Network Bernard and Ava Feldman Andres Fernandez Cecile and Mario Fernando Roxane Fett Molly and Edward Ficarra The Fiftieth Anniversary Foundation Jason Finney Barbara and Steve Fleissner Julie and Keith Fleming William and Vera Flynn Jim and Nancy Foran Cynthia Ford Kurtis Fouts Bruce Fox DEM PA - Foot & Ankle Center of Silver Spring Paul Franceschi and Allison Amon Jack and Margaret Fraker David and Linda Frank Charles and Victoria Frankel Robert and Margaret Franks Friedman Foundation Darcy Froehlich Michael and Amy Fullmer G.T.T. Inc. Richard and Barbara Gardner Scott and Janet Garley Brandon Garnett Fred and Mary Garrison Alfred and Johanna Garzino Joy Gaston Gerald and Leslie Gates Martin and Jeanne Gavin Robert and Carrie Gennuso Laurie Gershon Mark and Concetta Gessler Matt and Jennifer Geyso Kelly Gibbons Richard and Joan Gibbs James and Mary Gilewski Jaycee and Laleen Gilewski Dennis and Mimi Gillette James and Nanna Gilley Katrina Gleber Ryan and Amanda Gochenaur Harlan and Pamela Gohl Golden Valley Products Larry and Rose Marie Goodhart Arthur and Judy Goodkind Claude Graham Karen Grasso William and Sarah Gray Joan Green Linda Greene William Greene Rhonda Gresham The Law Office of Bernard S. Grimm Margaret and Joseph Griscti Robert Gross Jeffrey Grossman Robert and Kathryn Groves Henry and Janet Gruver Ajay Gupta Wendy Guy Thomas and Sharon Gwinn Gene and Leah Hageman Gretchen Hagerty Law Offices of Sheila Starkey Hahn, PC John and Nancy Hall Robert and Shannon Hanks-Grandia Karen Hannon John and Camille Hargreaves Jeremy and Erin Harlan Heidi Harrison Heidi Hartge Dan and Tricia Hase Donald and Florence Hauge Richard Hayden Larry and Mary Hayes James Hedrick Ron and Ann Heffron Rebecca Heidel Scott and Juliet Heimberg Brett Heineman Karleen Heller Randall and Robyn Heller Dave and Mary Henke Craig and Allison Henning Susan Henry Karen Hermelin Eddie and Lauren Hernandez Larry Heuett Linda Hicks Kerry Higgins Highlands Ranch Automotive, Inc. Richard and Leanne Hilger Donald and Jacqueline Hillner Donald and Sheila Hintze Garrick Hodge David and Shelley Hollan Hollywood Booster Club Holmdel PBA 239 Chris Holubowicz and Pam Sztukowski Richard and Katherine Horan Tommy and Elizabeth Hord Thomas Horner Lorraine Horton Marianna Horton Angela Houck Christopher Howe Henry and Angela Hribar Ralph and Phyllis Huemann David Huether Francis and Tracy Huiras John and Alice Hulbert Bill and Janis Hunnicutt Blake and Kara Hunnicutt Mike and Theresa Hunt Jackson and Catherine Hunter Daniel and Linda Hurley HVAC Mechanical Service, LLC Thomas and Polly Hyatt The Hyman Family Charitable Trust Foundation Shirley Hyman IDS Scheer Impact Consumer Research LLC Impruv Contractors Intergro Rehab Services Steve and Eva Ippolitto Paul and Lori Iverson Don and Fumiyo Iwatani J & H Investments, Inc. J.Bols Media Kenneth Jaffe Cheryl Jannarone Christopher Jefferies Jillians David and Karla Johns Josephine Johns Gregory Johnson Jared and Tracy Johnson Jay and Lisa Johnson Phil and Karen Johnson Robert and JH Johnson Kevin and Erin Jones Scott and Christina Jones James Joven JT Magen & Company Judicial Arbiter Group, Inc. Nausheen Juma Daniel and Barbara Justen Douglas Kaimakis Theresa Kaminski William and Judith Kamperman Janet Kappes Michael and Carol Keilen Kevin and Melanie Keller Steven and Jan Keller Kemper Educational & Charitable Fund Christopher and Beth Kemph Karen Kenny William and Jeannette Kerrigan Nancy Kevin Elizabeth King John and Gloria King Steve and Ann Klein Drew and Jessica Klepchick Knights of Columbus Council 8887 Raymond Koenig Robert and Eileen Koenig Mark and Dawn Koers Robert Kohl Joseph and Beverly Kozlowski Kim Kraft Russell and Merry Kraft David and Deborah Krecklow Fred and Lyn Krinsky Arnold Kristof Gayle and Layne Kruse Erin Kucerik Germaine and Patricia Kuhlman Michael and Nancy Kutner Young and Hee Kwak L&M Inc. Joseph La Flamme Lake Auto Sales Lakefront Auto Glass & Repair Bonnie Lee LaMadeleine Paul LaMadeleine Jennifer Lammey Jared Landkamer Sarah Langenohl D. Clair Lapp James Lara Amy Larson Larson Hay, LLC Peter and Alice Lassally Roger Lathrop Laxmi Inc. William and Lise Leach Robert Leighton Nancy Leonard Gilbert and Susan Levine 19 Jim Levitan Eleanore Lewis Gregory Lewis John and Laurie Lewis Stephen Lewis Steven and Valerie Lewis Kris Liacopoulos Sylvia Lief Linear Technologies Claire Liquorman Douglas Loewe Al and Marisa Lopez Crystal Lopez Stephen and Catharine Lorberbaum Jason and Lisa Lovell Charles Luke Martin and Arlene Lush Robert and Judy Luther Daniel Lynch Tina Lyon Donald and Michele Lyons M/A-Com Federal Credit Union Brian and Judith Madden Elizabeth Mahoney Don and Sue Manion Stephen and Kirsten Manton Timothy and Holly Manzone Marine Fueling Service, Inc. Mario Industries of Virginia, Inc. Myriah Markey Alan Marshall James and Nan Martin James and Rhona Martin John and Patricia Martin Kevin and Carrie Martin Bernabe and Lucy Martinez Fred and Nina Marton Marvin Masel Mason’s Carwash and Quick Lube The Masters School, Inc. Mathews, Reich, Perna & Rottermod, PC Donald May Stephen and Patricia Mayer 20 Kevin and Sarah McCain Dorothy McCann Robert McCarthy William and Susan McClintock Arthur and Beverly McCort Rachel McCoy Patrick and Patricia McCulley Gregory and Heather McCummings Charles and Theresa McFadden McKenna, Dupont, Higgins & Stone, PC Michael and Patricia McMullen Robert and Mary Melcher Douglas and Roseann Melville Julio and Elizabeth Mercado Robert and Angela Mercuri James and Marcie Merrow Paul and Kate Meyer James and Nancy Meyhoefer Walter and Carola Michael Timothy and Judith Michel Midtown Office Park, Inc. Midwest Sign & Screen Printing Supply Co Inc. Daniel Miles Ronald and Hope Miles Bernard and Deborah Miller Damon and Robin Miller Mark and Sheryl Miller Michael and Cathy Miller Mike Miller Rocky and Donna Mills Joseph and Marjorie Mirto Jason and Dena Mitchell Marilyn Modjeski Harland and Patricia Moidel Jeffrey Mooradian Troy Moore Stephen and Susan Morrissey Mortgage Assistance Company LLC Joel Moss Lisa Moss Charles and Frankie Moyers Stephen Mroz James and Patricia Mulcahy Mullett Excavating LLC Dwayne and Diane Munneke Keith and Ruth Munneke Elizabeth Munoz Mitch and Cindy Munt George and Ruth Murduch Roger and Deborah Murphy Michael and Janet Murray T.F. Murray Bob and Carol Myers Nick and Lenore Nanni Barbara Nason William and Wanda Neely John Nelson Michael Netta Neurogy LLC Mixa Nguyen Cherisse Nicastro Robert and Jennifer Nicholson David Nicklin Antoinette Nimphius Natalie Noakes Margery Nolen Northwest Golf Practice & Learning Center NU Tech Healthcare Management, LTD Stephen OBrien Matthew O’Connell Jack and Sandra O’Connor Patti Ogden Deborah Okano James and Mary Oliver William and Gina-Marie Oliver (WM Oliver Properties LLC) John and Kim Olson Lance and Julie Olson Douglas and Lisa O’Neill William and Sherri Orr Mark Osborn John Otterson Ottolino Winters Huebner, Inc. Jeanne and Pete Outhwaite Outstate Communications Ross Paitich Palmer Marketing Group, Ltd. Shams Panjwani George and Joy Pantelis Jay Parisi Park Meadow Chevrolet, Inc. Emma Parmee Partners Rx Management, LLC Bhavin Patel Nishat Patel Pathfinders Insurance Agency Kathleen Pawlik David and Barbara Pela Pelham Brokerage, Inc. Elizabeth and Angelo Peloso Sandra Persad James Pew Richard and Natalie Phillips Pierson Environmental Services, Inc. Yves Pinsonneault and Nathalie Simoneau Plant Escape, Inc. Charles and Bonnie Pletke Kathleen Podlas Scott and Lora Poepping Poggemeyer Design Group Bernard and Marsha Pointer Michael Polacco Paul Polyanski Brian Pope Christina Powell Misty Powell PPG Industries Prime Benefits, Inc. Printing Plus Progressive Handling Inc. Diane Pry Richard and Judith Purcell Gregory and Nancy Putz Roger and Linda Quick Nick and Amy Quintana Wayne and Cynthia Racinowski Edward and Bettina Radburn Kamal and Kathleen Raisani Robert Randall Deborah Rapaport Carl and Janine Rauscher Randy and Kim Rawlings Raylyn Properties, LLC Rebel Dozer Service & Construction, Ltd. Joan Reeves Refactory Minerals Company, Inc. Regional Reporting Inc. Don Reid Robert and Margaret Reidenbaugh Michael and Joy Rembold J. Rhead Medical Illustration, Inc. Donna Ricciardelli James and Beth Rice Richloom Fabrics Group, Inc. Philip and Noelle Richmond Karen Robinson Patrick and Maureen Roche Rock Martin Jewelers Ryan Rodkey Phillip and Wendy Rogerson Robert and Katharine Rosenau Peter and Barbara Rosenfeld David Rosenstein and Tori Nourafchan David and Deborah Ross Kelly Ross Vandy Rudkin Rudnick, Addonizio, & Pappa Raymond Runner Daniel Russo Harriet Rust Rusty Joal, Inc. Rutherfoord International The Ryan Lawfirm Greg Ryley Wesley and Eileen Ryun S & S Instruments Inc. Flavio and Janet Sabucco Kurt and Kimberly Sahlin Barbara Sales R. 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Six D Farms Chris and Elisabeth Skillin Monica Sluyter Peter Small 21 Vincent and Terri Smart Brian and Patricia Smith Edgar Smith Lauren Smith Mary Smith Smith Gatta Gelok Sherryn Solito-Forsen Steven Solow and Jean Simons Sonicscrubber, LLC Sons of the American Legion Wayne and Joann Sos Margaret Spiewak Gail Spitzer James and Kristi Sprout St. Patrick Parish James and Susan Stacey Melvin and Beverly Stacey Chris and Lisa Stamulis Star Light Charities, Inc. Pat and Harriet Starr State Bank of Fairbault Lynn Stauffacher Gerard and Theresia Steenman Sanford Steiner Steiner-Atlantic Corp. Stenco Supply Co, Inc. Roy and Jamie Stephens Carl and Rosemary Sterk Steve-N-Kids Mary Sue Stevens Molly Steward Eugene Stockel Fred Stodder Edward and Jane Stone Don Stout John Stout Randy and Colleen Stowell Pablo Straka Wilfrid Stride Francis and Ann Marie Sullivan John and Darlene Sullivan Summit Financial Group Inc. Jeffery and Wendy Sunahara 22 Superior Drywall Dirk and Kimberly Suringa Joan Sutton Matthew and Kristine Sweeney Tagan Construction Services, LLC Taggart’s Ice Cream, Inc. Howard and Patti Taxe Thomas and Martha Thill Jeffrey Scott Thomas Timeworks, Inc. Clock Co ToddCo Inc. Howard and Andria Topel Douglas Torrey Touraj and Vida Touran Michael Traina M. Ledoux Transport Tanya Traykovski Andrew and Helen Triemer William and Glenda Triemer Matt Trinka TRI-STATE TIRE Michael and Debra Trundle Tuscaloosa Woodmen Lodge Kathi Tuzzio UBS Financial Services, Inc. Gordon and Heather Ueland Doug Ulwick (Ulwick Affiliates Architects) UMB Bank, N.A. William Umphred V & D Fresco Edward VanderVeen William and Donna Varone Frederick and Deborah Waddell Alfred and Michele Wagner Elise Waits Walberg, Dagner & Tucker, PC Paul and Diane Wallner Jim and Tabitha Walsh Rupert and Judith Warburton Molly Ward W.D. Ward Warren & Duggan PLLC Edward and Edith Wartelle Edward and Jennifer Weaver Craig and Darci Weaver Robert and Catherine Webster Russell Weerth Glenn and Barbara Wegryn Steve Weingarth Mark and Sally Welton George and Rebecca Wendel Susan Westfall The Westport School Childcare Westwood Professional Services, Inc. Jason and Adrienne Whaley Donald and Karen Whitaker M. Wade and Tracy Whitman D. Scott and Nancy Whittington Steve and Julie Whitworth Douglas and Gayle Wiese Ron Wiesel Carl and Sheila Wiezalis Charles and Kristen Wilk Daniel and Kathy Wilke Mary Williams Wire Products Supply Co. Jeff and Nancy Wisot Natalie Witt Charles and Pam Wolthuis Nona Wood Wren High School Laura Wyskiel Harold and Beverly Xavier XSYS Print Solutions William and Nancy Youmans Nancy Young Kristen Yount Cathy Zardas Gregory and Monique Zarotney Richard and Carolyn Zebrowski Eugene and Theresa Zebrowski Matthew and Tracy Zimpfer Partners (Gift in Kind) Access Hollywood Alena All’Angel American B&D American Idol Bacchus Leon Baker (FarrahOlivia) Mario Batali Steve Bidgood and Rich Deutsch (Salt Creek Grille) Charles Bock, Jr. Boston Common Magazine Andy and Mary Bott Richard and Cindy Bott Buffalo Wild Wings Billy Bush John Cappadonna and David Frye (Bayside Manor) Tony Capparelli Tom Cappello and Dagoberto Sanchez (Gaetano’s) Damon Casatico, Charity Benefit Auction CBS Radio Chamard Vineyards Clairol Clothes Off Our Back Comedy Connection, Boston Conrad-Pyle Company David Cowles Diageo Chateau & Estate Wine Doug Douty (Douty Brothers Lusty Lobster) Jimmy Dunn Tim Elliott (Mie N Yu) Steve Falco (Falco Brother’s Catering) Fiji Water Ed Foran, Jack McCann, Osgual Olmedo, and Wolfgang Weichert (Merri-Makers Catering and Special Events) Frank and Laura Gallagher Jeff Garlin GKS, Inc Gotham Magazine Dan Gimaldi Bill Hahn (Monmouth County Culinary Education) Michael Harr (Butterfield 9) HAT WORLD, Inc. Teri Hatcher Chris Hawkey and the Powerplay Bob Higgins (Windansea) Francois Hurtel Ingram Design Studio Neil Jordan (McLoone’s Riverside Dining) Kahlen Studios Daniel Kenney (Willard Intercontinental Hotel) Keurig Coffee KFAN – AM 1130 Kids Choice Awards Mike Kriborian (Cooper Canyon) Martin Lackovic (Provisions) LaForce & Stevens Lance Christopher Salon Sylvia Lief Enzo Livia (Spezie) Kenny Loggins Los Angeles Confidential Magazine Eric Manvelle (Red) Matawan (Amravathi Indian Restaurant) McLoone’s Pier House Milius Mills Wine & Spirits Modern Studio Furnishings Julianne Moore Natalie Morales Rich Morgan (Bahrs Landing Famous Restaurant) Mount Cinnamon on Grand Anse Beach The Music Box@Fonda New York Giants Darren Norris (Ridgewells Caterers) Joe Oliver (Bella Palmero) Oronoco Fran Ostrow Piaget POM Tea R&R Marketing Marcelo Ramagen (Gifford’s Ice Cream) Rhino Entertainment John Roberts Shaun Robinson Ray Romano The Rothberg Institute for Childhood Diseases Saks Fifth Avenue Santa Lucia Estate Coffee Sapporo Martin Saylor (Hunt Valley Inn) Sherri Shepherd Spa on Location Stila Stolichnaya Russian Vodka Jim Swenson (National Press Club) James and the late Elizabeth Terry TIGI Linea, LLP Jeff Tunks (DC Coast, Ceiba, TenPenh) Unbound Energy Drink Tony V. Variations Hair Color Specialist Variety K.N. Vinod (Indique) Bryan Voltaggio (Charlie Palmer Steak) Johnny Walker Washington Selections Wire Image The TS Alliance strives to correctly recognize all donors. We apologize in advance for any errors, omissions or misspellings in this annual report. Please call our Development Department at 1-800-225-6872 with any corrections. 23 The Endowment Fund The Eternal Flame Society Endowment Named Funds The Tuberous Sclerosis Alliance Endowment Fund is a separate fiduciary organization specifically chartered to receive gifts that will be used to generate a permanent income stream that will help fulfill the mission of the TS Alliance. The Endowment Fund will ensure that the TS Alliance has a permanent source of funding to better serve families touched by tuberous sclerosis complex through research, support services and education. “Keepers of the Flame” include members of the TS Alliance community who have designated a planned gift through their wills or estate to the TS Alliance Endowment Fund or the TS Alliance. We are pleased to honor the following distinguished members of the Eternal Flame Society: For gifts of $25,000 or more (or with a pledge payable over five years), a donor has the opportunity to name a fund in honor of someone. We are deeply grateful for the following named funds: Fiscal Year 2007: July 1 2006 - June 30, 2007 ALLIANCE SOCIETY ($1,000,000 and above) Estate of Alma A. Tutrone ADVANCEMENT SOCIETY ($25,000 - $99,999) Glenn N. Howatt Foundation Ken and Shonnie Johnson Philip and Marion Winsor ENRICHMENT SOCIETY ($5,000 - $9,999) Will and Kay Cooper (WNC & Associates) INVESTMENT SOCIETY ($250 - $4,999) Herbst Foundation Mark H. Hyman and Sheryl Neuman Magdalena Lutsky Patrick M. McCulley Muriel Pattis SAF-T-SWIM, INC. West Chicago Garden Club The Robert Wood Johnson Foundation 24 Anonymous Michael and Millicent Augustine Jeffery and the late Gloria Benham Matt and Treasa Bolger Scott and Jen Burton Marguerite Cleveland John and Katherine Conrad Will and Kay Cooper Rich and Reiko Donato David and Laura Grimes Shannon Hackley Jeffrey and Lisa Hargreaves Clara Harwell James and Amy Hobbs Ken and Shonnie Johnson Arnold and Carol Kamm Steve and Laura D. Kozisek David and Cathy Krinsky The late Craig T. Lewis Doug and Linda Loftus James Lynch Cindy D. Lynch Samuel and Donna McGaha David and Jan Mintz David and Penney Parkes Pat and Jennifer Rolfes Dave and Nancy Scott Fred and Isle Smith John and Janine Steenman Kathy M. Trapp The late Alma A. Tutrone Jim and Nancy Weir Philip and Marion Winsor Barbara K. Witten and William R. Bradley The late Frieda K. Zimmerman Megan Augustine Fund John A. Conrad Jr. Memorial Fund Carrie Cooper Memorial Fund Lauren E. Krinsky Fund The Lawler Fund Cade Scott Fund Upon her passing, Alma Tutrone left a legacy gift of $2.75 million to the Tuberous Sclerosis Alliance Endowment Fund, a testament to her 30-year friendship with Michael Augustine, one of the founding fathers of Tuberous Sclerosis Alliance Endowment Fund. This is the single largest gift the Tuberous Sclerosis Alliance or the Tuberous Sclerosis Alliance Endowment Fund has ever received, and Alma’s generosity will have a lasting impact on the organization. Leadership TS Alliance Board of Directors TS Alliance Staff Andy Bott, Chair Farmingdale, NJ Janie Frost, R.N. Woodbury, MN Arien Malec Oakland, CA Kari Luther Carlson President and Chief Executive Officer Terry Elling, Vice Chair Fairfax, VA Jeffrey Hargreaves Merrimack, NH Kathy Mayrsohn Key Biscayne, FL Erika A. Albini Regional Manager of Community Outreach, West Coast Cathy Krinsky, Secretary Laguna Beach, CA Elizabeth Petri Henske, M.D. Philadelphia, PA Michael Michael Brookline, MA Gail Alexander Office Manager John Steenman, Treasurer Pleasanton, CA Christy Hobart Santa Monica, CA MaryJane Mudd Houston, TX Kenza Carrington Administrative Assistant Milly Augustine San Gabriel, CA Georgia Johnson Brookline, MA Hiroaki (Rocky) Onda, Ph.D. Trenton, ME Danté Douglas Development Assistant Mark Carroll Saratoga, CA Megan Johnson Santa Barbara, CA Nicole Seefeldt West Hempstead, NY Tyler Hoffman Database Coordinator Will Cooper, Sr. Newport Beach, CA Fred Linder Boulder, CO Chris Sheffield North Hollywood, CA Dena Hook Director of Advocacy and Outreach William Ford Chevy Chase, MD Thomas Lindsey Staten Island, NY Elizabeth Thiele, M.D., Ph.D. Newton, MA Jaye Isham Senior Director of Communications David Neal Franz, M.D. Cincinnati, OH Cindy Lynch Littleton, CO Rob Thurston Provo, UT JoAnne Nakagawa Director of Clinical Projects Tim Rogers Regional Manager of Community Outreach, East Coast TS Alliance Endowment Fund Board of Directors Rob Thurston, Chair Provo, UT Mark Carroll Saratoga, CA Julie Blum, Secretary Potomac, MD Will Cooper, Sr. Newport Beach, CA John Steenman, Treasurer Pleasanton, CA Robert Groves Brighton, MI Andrew Bott Farmingdale, NJd Cathy Krinsky Laguna Beach, CA Allen Ross Chief Financial Officer Jenny Smiley Director of Community Outreach and Midwest Region Katie Smith Science Coordinator Aaron Tolentino Outreach Coordinator William Tolentino Senior Manager of Development Vicky Holets Whittemore, Ph.D. Vice President and Chief Scientific Officer 25 International Scientific Advisory List Cheryl Lyn Walker, Ph.D., Chair Ruth and Walter Sterling Professor of Carcinogenesis Science Park Research Division Director, Molecular Genetics and Environmental Carcinogenesis Research Core NIEHS Center for Research on Environmental Disease UT MD Anderson Cancer Center Smithville, TX Peter Crino, M.D., Ph.D. Assistant Professor of Neurology University of Pennsylvania Philadelphia, PA Paolo Curatolo, M.D. Professor of Child Neurology and Psychiatry, Director, Child Neurology Unit, Tor Vergata University of Rome Rome, Italy Marcus Hengstschläger, Ph.D. Professor of Medical Genetics, Obstetrics and Gynecology Medical University of Vienna Vienna, Austria Elizabeth Petri Henske, M.D. Member Medical Sciences Division Fox Chase Cancer Center Philadelphia, PA Okio Hino, M.D., Ph.D. Professor of Pathology Juntendo University School of Medicine Tokyo, Japan Gregory Holmes, M.D. Section Chief of Neurology Dartmouth-Hitchcock Medical Center Lebanon, NH 26 Professional Advisory List Ann Hunt Head of Research Tuberous Sclerosis Association Oxfordshire, Oxford, UK Frances Jensen, M.D. Associate Professor of Neurology Children’s Hospital & Harvard Medical School Boston, MA Sergiusz Jozwiak, M.D., Ph.D. Professor and Head of Child Neurology The Children's Memorial Health Institute Warsaw, Poland David Kwiatkowski, M.D., Ph.D. Associate Professor of Medicine Brigham & Women’s Hospital & Harvard Medical School Boston, MA Hope Northrup, M.D. Professor of Pediatrics Director, Division of Medical Genetics University of Texas –Houston Houston, TX Duojia Pan, Ph.D. Associate Professor of Molecular Biology and Genetics Johns Hopkins University School of Medicine Baltimore, MD Bernardo Sabatini, M.D., Ph.D. Assistant Professor of Neurobiology Harvard Medical School Boston, MA Julian Sampson, D.M. Professor and Head of Department, Medical Genetics Institute of Medical Genetics Wales College of Medicine Cardiff University Cardiff, Wales, UK Michael D. Frost, M.D., Chair The Minnesota Epilepsy Group, P.A. St. Paul, MN Peter J. Aronson, M.D. Wayne State University Department of Dermatology Detroit, MI Stephen Ashwal, M.D. Loma Linda School of Medicine Department of Pediatrics Loma Linda, CA Lori L. Batchelor, B.S.N., R.N. Department of Hematology Children’s Hospital Fort Worth, TX E. Martina Bebin, M.D. University of Alabama at Birmingham Department of Neurology Huntsville, AL John Bissler, M.D. Children's Hospital Medical Center Division of Nephrology and Hypertension Cincinnati, OH Peter Black, M.D., Ph.D. Children's Hospital Department of Neurosurgery Boston, MA Candida Brown, M.D. Children’s Hospital Oakland Division of Neurology Oakland, CA Diane C. Chugani, Ph.D. Children's Hospital of Michigan Department of Neurology Detroit, MI Harry T. Chugani, M.D. Children's Hospital of Michigan Pediatric Neurology Detroit, MI David Neal Franz, M.D. Children's Hospital Medical Center Department of Neurology Cincinnati, OH Susan Koh, M.D. University of California, Los Angeles Division of Pediatric Neurology Los Angeles, CA E. Steve Roach, M.D. Ohio State University Department of Neurology Columbus, OH Peter Crino, M.D., Ph.D. University of Pennsylvania School of Medicine Department of Neurology PENN Epilepsy Center Philadelphia, PA David Frim, M.D., Ph.D. The University of Chicago Children's Hospital Department of Neurosurgery Chicago, IL Michael Kohrman, M.D. University of Chicago Department of Pediatrics Chicago, IL Mustafa Sahin, M.D., Ph.D. Children’s Hospital Department of Neurology Boston, MA David J. Kwiatkowski, M.D., Ph.D. Genetics Lab, Hematology Division Brigham and Women’s Hospital Harvard Medical School Boston, MA Steven P. Sparagana, M.D. Texas Scottish Rite Hospital for Children Department of Neurology Dallas, TX Orrin Devinsky, M.D. NYU Epilepsy Center New York, NY Francis J. DiMario, Jr, M.D. Connecticut Children’s Medical Center Division of Pediatric Neurology Hartford, CT Michael S. Duchowny, M.D. Miami Children's Hospital Department of Neurology Miami, FL David W. Dunn, M.D. Riley Hospital for Children Indiana University School of Medicine Department of Neurology Indianapolis, IN Nancy J. Elling, B.S.N., R.N. Children’s National Medical Center Department of Neurology Fairfax, VA Kevin C. Ess, M.D., Ph.D. Vanderbilt University Department of Neurology Nashville, TN David H. Ewalt, M.D. Urology Clinic of North Texas Dallas, TX Patricia A. Gibson, M.S.W. Wakeforest University School of Medicine Baptist Medical Center Department of Neurology Comprehensive Epilepsy Information Service Winston Salem, NC Elizabeth Petri Henske, M.D. Fox Chase Cancer Center Department of Medical Oncology Philadelphia, PA Deborah Holder, M.D. University of Pittsburgh Department of Neurology Pittsburgh, PA John Hulbert, M.D. Urologic Physicians, P.A. Edina, MN Janine Lewis, M.S., C.G.C. Aspen Systems Rockville, MD Raymond S. Kandt, M.D. Johnson Neurological Clinic High Point, NC Bryan H. King, M.D. Children’s Hospital Department of Psychiatry Seattle, WA Mark Mausner, M.D. Bethesda, MD William McClintock, M.D. Children's National Medical Center Department of Neurology Fairfax, VA Frank McCormack, M.D. University of Cincinnati School of Medicine Pulmonary Division Cincinnati, OH Greg Mlynarczyk, D.D.S. Santa Rosa, CA Hope Northrup, M.D. The University of Texas Medical School at Houston Department of Pediatrics, Division of Medical Genetics Houston, TX Penny Prather, Ph.D. Educational Enhancement Center Newton, MA Elizabeth A. Thiele, M.D., Ph.D. The Carol & James Herscot Center for Children & Adults with TSC Massachusetts General Hospital Department of Neurology Boston, MA William G. Ward, M.D. Wake Forest University School of Medicine Baptist Medical Center Department of Orthopedic Surgery Winston Salem, NC Howard Weiner, M.D. New York University Medical Center Division of Pediatric Neurosurgery New York, NY Joyce Wu, M.D. University of California, Los Angeles Division of Pediatric Neurology Los Angeles, CA Raymond Yeung, M.D. University of Washington School of Medicine Division of Surgery and Medical Genetics Seattle, WA 27 National Tuberous Sclerosis Association, Inc. (d.b.a. TS Alliance) and Affiliate (TS Alliance Endowment Fund) Consolidated Statements of Financial Position June 30, 2007 and 2006 2007 2006 $ 455,131 8,088 330,264 3,382,878 201,179 $ 448,526 111 241,830 3,728,397 211,805 4,377,540 4,630,669 – 5,278,283 247,266 113,320 2,155,435 263,618 $ 9,903,089 $7,163,042 $ $ Assets Current Assets Cash Accounts Receivable Unconditional Promises to Give Short-Term Investments Prepaid Expenses Total Current Assets Unconditional Promises to Give Long-Term Investments Net Property and Equipment Total Assets Liabilities and Net Assets Current Liabilities Accounts Payable Gift Annuities Payable Accrued Compensation Accrued Vacation Deferred Revenue Total Current Liabilities Gift Annuities Payable - Long-Term Total Liabilities Net Assets Unrestricted Board-Designated Undesignated Total Unrestricted Temporarily Restricted Permanently Restricted Total Net Assets Total Liabilities and Net Assets 28 46,617 9,400 41,610 21,316 16,642 84,416 9,400 37,019 23,788 366,777 135,585 521,400 84,867 85,279 220,452 606,679 2,601,991 4,759,426 2,335,473 1,574,794 7,361,417 3,910,267 1,416,776 904,444 1,781,662 864,434 9,682,637 6,556,363 $ 9,903,089 $7,163,042 The Tuberous Sclerosis Alliance (TS Alliance) annually engages a certified public accounting firm to conduct an independent audit of its operations. The firm of Councilor, Buchanan & Mitchell, P.C. completed its 2007 audit and submitted an unqualified opinion to the TS Alliance Board of Directors who have approved the report of the auditors. The complete audited financial statements reported on by Councilor, Buchanan & Mitchell, P.C. are on file at the TS Alliance. To obtain a complete copy, please call (800) 225-6872. The 2007 summary was prepared by Councilor, Buchanan & Mitchell, P.C. from the audited consolidated statements of the TS Alliance and TS Alliance Endowment Fund. The relationship of the organizations requires consolidation per the Statement of Position (SOP) 94-3, Reporting of Related Entities by Not-for-Profit Organizations. In 2007, the TS Alliance Endowment Fund received an unrestricted bequest of $2,750,000, which is included in Contributions in the Consolidated Statement of Activities and Changes in Net Assets. Certain reclassifications have been made in the 2006 presentation to conform to the 2007 presentation. National Tuberous Sclerosis Association, Inc. (d.b.a. TS Alliance) and Affiliate (TS Alliance Endowment Fund) Consolidated Statements of Activities and Changes in Net Assets For the Years Ended June 30, 2007 and 2006 2007 Unrestricted Revenues and Support Special Events Less Cost of Direct Benefits to Donors Net Revenue from Special Events Contributions Memorials/Honorariums Other Organizations Dividends and Interest National Family Conference Other Conference Donations Change in Value of Split Interest Agreements Miscellaneous Net Assets Released from Restrictions Total Revenues and Support Expenses Program Services Family Services Research Government Relations Public Health Education Professional Education Total Program Services Supporting Services Management and General Fund-Raising Total Supporting Services Total Expenses Gains and Losses Net Realized and Unrealized Investment Gains Net Expenses, Gains and Losses $1,713,377 (284,757) 1,428,620 3,491,972 109,525 76,353 312,250 326,276 93,905 (8,988) 27,962 1,127,990 6,985,865 Temporarily Restricted $ 2006 Total Unrestricted Temporarily Restricted - $ 2,021,587 (318,421) $1,734,621 (179,417) $ 305,052 - 274,546 454,154 20,090 14,314 (1,127,990) 40,010 - 1,703,166 3,986,136 129,615 76,353 326,564 326,276 93,905 (8,988) 27,962 - 1,555,204 639,182 107,762 75,843 197,212 63,007 (1,132) 18,035 840,044 (364,886) 40,010 6,660,989 3,495,157 308,210 (33,664) Permanently Restricted $ Permanently Restricted $ Total - $ 2,039,673 (179,417) 305,052 242,466 15,449 (840,044) 22,880 - 1,860,256 904,528 123,211 75,843 197,212 63,007 (1,132) 18,035 - (277,077) 22,880 3,240,960 895,351 1,415,860 103,991 167,630 20,579 - - 895,351 1,415,860 103,991 167,630 20,579 537,037 1,284,619 110,501 174,760 8,174 - - 537,037 1,284,619 110,501 174,760 8,174 2,603,411 - - 2,603,411 2,115,091 - - 2,115,091 377,700 839,874 - - 377,700 839,874 331,518 629,025 - - 331,518 629,025 1,217,574 - - 1,217,574 960,543 - - 960,543 3,820,985 - - 3,820,985 3,075,634 - - 3,075,634 286,270 - - 286,270 134,441 - - 134,441 3,534,715 - - 3,534,715 2,941,193 - - 2,941,193 40,010 3,126,274 553,964 22,880 299,767 Changes in Net Assets 3,451,150 Net Assets, Beginning of Year, as Previously Reported Prior Period Adjustments 3,910,267 - 1,781,662 - 864,434 - 6,556,363 - 3,376,702 (20,399) 2,058,739 - 841,554 - 6,276,995 (20,399) Net Assets, Beginning of Year, As Adjusted 3,910,267 1,781,662 864,434 6,556,363 3,356,303 2,058,739 841,554 6,256,596 $7,361,417 $ 1,416,776 $ 904,444 $ 9,682,637 $3,910,267 $1,781,662 $ 864,434 $ 6,556,363 Net Assets, End of Year (364,886) (277,077) 29 "In the fight against tuberous sclerosis complex, heroes and hope abound . . ." 801 Roeder Road, Suite 750 Silver Spring, MD 20910 800-225-6872 www.tsalliance.org