SAFETY DATA SHEET 1. Identification Product identifier Tiadinil Other means of identification Item N-13282 Recommended use 3'-Chloro-4,4'-dimethyl-1,2,3-thiadiazole-5-carboxani lide For Laboratory Use Only Recommended restrictions None known. Synonym(s) Manufacturer/Importer/Supplier/Distributor information Manufacturer Company name Address Telephone Website E-mail Emergency phone number Chem Service, Inc. 660 Tower Lane West Chester, PA 19380 United States Toll Free Direct www.chemservice.com info@chemservice.com Chemtrec US Chemtrec outside US 800-452-9994 610-692-3026 800-424-9300 +1 703-527-3887 2. Hazard(s) identification Physical hazards Not classified. Health hazards Acute toxicity, oral Environmental hazards Not classified. OSHA defined hazards Not classified. Category 4 Label elements Signal word Warning Hazard statement Harmful if swallowed. Precautionary statement Prevention Wash thoroughly after handling. Do not eat, drink or smoke when using this product. Response If swallowed: Call a poison center/doctor if you feel unwell. Rinse mouth. Storage Store away from incompatible materials. Disposal Dispose of contents/container in accordance with local/regional/national/international regulations. Hazard(s) not otherwise classified (HNOC) None known. Supplemental information Not applicable. 3. Composition/information on ingredients Substances Chemical name Tiadinil Common name and synonyms CAS number % 3'-Chloro-4,4'-dimethyl-1,2,3-thiadiazole-5-c arboxanilide 223580-51-6 100 *Designates that a specific chemical identity and/or percentage of composition has been withheld as a trade secret. 4. First-aid measures Inhalation Move to fresh air. Call a physician if symptoms develop or persist. Skin contact Wash off with soap and water. Get medical attention if irritation develops and persists. Material name: Tiadinil 19688 Version #: 01 Issue date: 01-14-2015 SDS US 1/6 Eye contact Rinse with water. Get medical attention if irritation develops and persists. Ingestion Rinse mouth. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Most important symptoms/effects, acute and delayed Direct contact with eyes may cause temporary irritation. Indication of immediate medical attention and special treatment needed Provide general supportive measures and treat symptomatically. In case of shortness of breath, give oxygen. Keep victim warm. Keep victim under observation. Symptoms may be delayed. General information In the case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). Ensure that medical personnel are aware of the material(s) involved, and take precautions to protect themselves. 5. Fire-fighting measures Suitable extinguishing media Water fog. Foam. Dry chemical powder. Carbon dioxide (CO2). Unsuitable extinguishing media Do not use water jet as an extinguisher, as this will spread the fire. Specific hazards arising from the chemical During fire, gases hazardous to health may be formed. Special protective equipment and precautions for firefighters Self-contained breathing apparatus and full protective clothing must be worn in case of fire. Fire-fighting equipment/instructions Use water spray to cool unopened containers. Specific methods Use standard firefighting procedures and consider the hazards of other involved materials. General fire hazards No unusual fire or explosion hazards noted. 6. Accidental release measures Methods and materials for containment and cleaning up Keep unnecessary personnel away. Keep people away from and upwind of spill/leak. Wear appropriate personal protective equipment. Ensure adequate ventilation. Local authorities should be advised if significant spillages cannot be contained. For personal protection, see section 8 of the SDS. This product is miscible in water. Stop the flow of material, if this is without risk. Following product recovery, flush area with water. For waste disposal, see section 13 of the SDS. Environmental precautions Avoid discharge into drains, water courses or onto the ground. Personal precautions, protective equipment and emergency procedures 7. Handling and storage Precautions for safe handling Conditions for safe storage, including any incompatibilities Do not taste or swallow. Provide adequate ventilation. Wear appropriate personal protective equipment. Observe good industrial hygiene practices. When using, do not eat, drink or smoke. Wash hands thoroughly after handling. Store in original tightly closed container. Store away from incompatible materials (see Section 10 of the SDS). 8. Exposure controls/personal protection Occupational exposure limits No exposure limits noted for ingredient(s). Biological limit values No biological exposure limits noted for the ingredient(s). Appropriate engineering controls Good general ventilation (typically 10 air changes per hour) should be used. Ventilation rates should be matched to conditions. If applicable, use process enclosures, local exhaust ventilation, or other engineering controls to maintain airborne levels below recommended exposure limits. If exposure limits have not been established, maintain airborne levels to an acceptable level. Individual protection measures, such as personal protective equipment If contact is likely, safety glasses with side shields are recommended. Eye/face protection Skin protection Hand protection Other For prolonged or repeated skin contact use suitable protective gloves. Wear suitable protective clothing. Respiratory protection In case of insufficient ventilation, wear suitable respiratory equipment. Thermal hazards Wear appropriate thermal protective clothing, when necessary. General hygiene considerations When using, do not eat, drink or smoke. Always observe good personal hygiene measures, such as washing after handling the material and before eating, drinking, and/or smoking. Routinely wash work clothing and protective equipment to remove contaminants. 9. Physical and chemical properties Appearance Physical state Solid. Material name: Tiadinil 19688 Version #: 01 Issue date: 01-14-2015 SDS US 2/6 Form Solid. Color Not available. Odor Not available. Odor threshold Not available. pH Not available. Melting point/freezing point 233.96 °F (112.2 °C) Initial boiling point and boiling range Not available. Flash point Not available. Evaporation rate Not available. Flammability (solid, gas) Not available. Upper/lower flammability or explosive limits Not available. Flammability limit - lower (%) Flammability limit - upper (%) Not available. Explosive limit - lower (%) Not available. Explosive limit - upper (%) Not available. Vapor pressure Not available. Vapor density Not available. Relative density Not available. Solubility(ies) Solubility (water) 13.2 mg/l at 20 °C Partition coefficient (n-octanol/water) Not available. Auto-ignition temperature Not available. Decomposition temperature Not available. Viscosity Not available. Other information Density 1.47 at 20 °C Molecular formula C11H10ClN3OS Molecular weight 267.7 10. Stability and reactivity Reactivity The product is stable and non-reactive under normal conditions of use, storage and transport. Chemical stability Material is stable under normal conditions. Possibility of hazardous reactions No dangerous reaction known under conditions of normal use. Conditions to avoid Contact with incompatible materials. Incompatible materials Strong oxidizing agents. Hazardous decomposition products No hazardous decomposition products are known. 11. Toxicological information Information on likely routes of exposure Harmful if swallowed. Ingestion Inhalation No adverse effects due to inhalation are expected. Skin contact No adverse effects due to skin contact are expected. Eye contact Direct contact with eyes may cause temporary irritation. Symptoms related to the physical, chemical and toxicological characteristics Direct contact with eyes may cause temporary irritation. Information on toxicological effects Acute toxicity Harmful if swallowed. Material name: Tiadinil 19688 Version #: 01 Issue date: 01-14-2015 SDS US 3/6 Product Species Test Results Tiadinil (CAS 223580-51-6) Dermal LD50 Rat > 2000 mg/kg Inhalation LC50 Rat > 2.48 mg/l, 4 hours Oral LD50 Rat > 6147 mg/kg * Estimates for product may be based on additional component data not shown. Prolonged skin contact may cause temporary irritation. Skin corrosion/irritation Direct contact with eyes may cause temporary irritation. Serious eye damage/eye irritation Respiratory or skin sensitization Not available. Respiratory sensitization This product is not expected to cause skin sensitization. Skin sensitization Germ cell mutagenicity No data available to indicate product or any components present at greater than 0.1% are mutagenic or genotoxic. Carcinogenicity This product is not considered to be a carcinogen by IARC, ACGIH, NTP, or OSHA. US. OSHA Specifically Regulated Substances (29 CFR 1910.1001-1050) Not listed. This product is not expected to cause reproductive or developmental effects. Reproductive toxicity Specific target organ toxicity single exposure Not classified. Specific target organ toxicity repeated exposure Not classified. Aspiration hazard Not available. 12. Ecological information Ecotoxicity The product is not classified as environmentally hazardous. However, this does not exclude the possibility that large or frequent spills can have a harmful or damaging effect on the environment. Product Tiadinil (CAS 223580-51-6) Crustacea Other Species Test Results LC50 Daphnia 1.6 mg/l, 48 hours LC50 Rainbow Trout 3.4 mg/l, 96 hours * Estimates for product may be based on additional component data not shown. No data is available on the degradability of this product. Persistence and degradability Bioaccumulative potential No data available. Mobility in soil No data available. Other adverse effects No other adverse environmental effects (e.g. ozone depletion, photochemical ozone creation potential, endocrine disruption, global warming potential) are expected from this component. 13. Disposal considerations Disposal instructions Local disposal regulations Hazardous waste code Waste from residues / unused products Contaminated packaging Collect and reclaim or dispose in sealed containers at licensed waste disposal site. This material and its container must be disposed of as hazardous waste. Do not allow this material to drain into sewers/water supplies. Do not contaminate ponds, waterways or ditches with chemical or used container. Dispose of contents/container in accordance with local/regional/national/international regulations. Dispose in accordance with all applicable regulations. The waste code should be assigned in discussion between the user, the producer and the waste disposal company. Dispose of in accordance with local regulations. Empty containers or liners may retain some product residues. This material and its container must be disposed of in a safe manner (see: Disposal instructions). Empty containers should be taken to an approved waste handling site for recycling or disposal. Since emptied containers may retain product residue, follow label warnings even after container is emptied. Material name: Tiadinil 19688 Version #: 01 Issue date: 01-14-2015 SDS US 4/6 14. Transport information DOT Not regulated as dangerous goods. IATA Not regulated as dangerous goods. IMDG Not regulated as dangerous goods. Not applicable. Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code 15. Regulatory information US federal regulations This product is a "Hazardous Chemical" as defined by the OSHA Hazard Communication Standard, 29 CFR 1910.1200. One or more components are not listed on TSCA. TSCA Section 12(b) Export Notification (40 CFR 707, Subpt. D) Not regulated. CERCLA Hazardous Substance List (40 CFR 302.4) Not listed. SARA 304 Emergency release notification Not regulated. US. OSHA Specifically Regulated Substances (29 CFR 1910.1001-1050) Not listed. Superfund Amendments and Reauthorization Act of 1986 (SARA) Immediate Hazard - Yes Hazard categories Delayed Hazard - No Fire Hazard - No Pressure Hazard - No Reactivity Hazard - No SARA 302 Extremely hazardous substance Not listed. SARA 311/312 Hazardous chemical No SARA 313 (TRI reporting) Not regulated. Other federal regulations Clean Air Act (CAA) Section 112 Hazardous Air Pollutants (HAPs) List Not regulated. Clean Air Act (CAA) Section 112(r) Accidental Release Prevention (40 CFR 68.130) Not regulated. Not regulated. Safe Drinking Water Act (SDWA) US state regulations US. Massachusetts RTK - Substance List Not regulated. US. New Jersey Worker and Community Right-to-Know Act Not regulated. US. Pennsylvania RTK - Hazardous Substances Not regulated. US. Rhode Island RTK Not regulated. US. California Proposition 65 California Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65): This material is not known to contain any chemicals currently listed as carcinogens or reproductive toxins. International Inventories Country(s) or region Australia Inventory name Australian Inventory of Chemical Substances (AICS) Canada Domestic Substances List (DSL) No Canada Non-Domestic Substances List (NDSL) No Material name: Tiadinil 19688 Version #: 01 Issue date: 01-14-2015 On inventory (yes/no)* No SDS US 5/6 Country(s) or region China Inventory name Inventory of Existing Chemical Substances in China (IECSC) On inventory (yes/no)* No Europe European Inventory of Existing Commercial Chemical Substances (EINECS) No Europe European List of Notified Chemical Substances (ELINCS) No Japan Inventory of Existing and New Chemical Substances (ENCS) No Korea Existing Chemicals List (ECL) No New Zealand New Zealand Inventory No Philippines Philippine Inventory of Chemicals and Chemical Substances (PICCS) No United States & Puerto Rico Toxic Substances Control Act (TSCA) Inventory No *A "Yes" indicates that all components of this product comply with the inventory requirements administered by the governing country(s) A "No" indicates that one or more components of the product are not listed or exempt from listing on the inventory administered by the governing country(s). 16. Other information, including date of preparation or last revision Issue date 01-14-2015 Version # 01 Health: 0 Flammability: 0 Instability: 0 NFPA ratings Disclaimer The above information is believed to be correct on the date it was last revised and must not be considered all inclusive. The information has been obtained only by a search of available literature and is only a guide for handling the chemicals. OSHA regulations require that if other hazards become evident, an upgraded SDS must be made available to the employee within three months. RESPONSIBILITY for updates lies with the employer and not with CHEM SERVICE, Inc. Persons not specifically and properly trained should not handle this chemical or its container. This product is furnished FOR LABORATORY USE ONLY! Our products may NOT BE USED as drugs, cosmetics, agricultural or pesticide products, food additives or as household chemicals. This Safety Data Sheet (SDS) is intended only for use with Chem Service, Inc. products and should not be relied on for use with materials from any other supplier even if the chemical name(s) on the product are identical! Whenever using an SDS for a solution or mixture the user should refer to the SDS for every component of the solution or mixture. Chem Service warrants that this SDS is based upon the most current information available to Chem Service at the time it was last revised. THIS WARRANTY IS EXCLUSIVE, AND CHEM SERVICE, INC. MAKES NO OTHER WARRANTY, EXPRESSED OR IMPLIED, INCLUDING ANY IMPLIED WARRANTY OF MERCHANTABILITY OR FITNESS FOR ANY PARTICULAR PURPOSE. This SDS is provided gratis and CHEM SERVICE, INC. SHALL NOT BE LIABLE FOR ANY INCIDENTAL, CONSEQUENTIAL OR CONTINGENT DAMAGES. Copyright © 2000-2014 Chem Service, Inc. All rights reserved except that this SDS may be printed for the use of a customer or prospective customer of Chem Service, Inc provided the entire SDS is printed. The SDS may not be placed in any database or otherwise stored or distributed in electronic or any other form. This product is furnished FOR LABORATORY USE ONLY. Material name: Tiadinil 19688 Version #: 01 Issue date: 01-14-2015 SDS US 6/6