Partner Highlights - Lake Nona Institute

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MEDICAL CITY PARTNERS INFORMATION
NEMOURS CHILDREN’S HOSPITAL…PAGE 2
ORLANDO VA MEDICAL CENTER…PAGE 8
SANFORD BURNHAM PREBYS MEDICAL
DISCOVERY INSTITUTE…PAGE 13
1
UNIVERSITY OF CENTRAL FLORIDA COLLEGE OF
MEDICINE…PAGE 10
UNIVERSITY OF FLORIDA RESEARCH &
ACADEMIC CENTER...PAGE 15
Updated 2/2016
MEDICAL CITY PARTNERS INFORMATION
NEMOURS CHILDREN’S HOSPITAL & THE NEMOURS FOUNDATION
VISION,
Our Promise: To treat every child as if they were our own.
MISSION &
Our Commitment: To do everything in our power to help children grow up healthy
VALUES
Mission: To provide leadership, institutions, and services to restore and improve the health of children
PRIMARY CONTACT
FUNDING*
through care and programs not readily available, with one high standard of quality and distinction,
regardless of the recipient's financial status.
Values: Excel ~ Respect ~ Serve ~ Honor ~ Learn
We believe that our shared values inform and inspire our activities, helping us build and sustain a culture of
trust. We are committed to doing whatever it takes to ensure our patients and families, visitors, colleagues,
and business partners experience a uniquely satisfying experience each time they interact with Nemours.
ABOUT
The Nemours Foundation supports one of the largest integrated pediatric health systems in the U.S.,
NEMOURS
including 50 pediatric subspecialty clinics, partner hospitals, and primary and urgent care clinics throughout
Delaware, Pennsylvania, New Jersey and Florida, including two free-standing children’s hospital in central
Florida and Delaware. Nemours provides clinical care for more than 300,000 unique patients per year.
Patient satisfaction scores for Nemours physician practices and hospitals are at or near the top 5 percent
nationally.
RESEARCH &
Your Child – Our Promise. Nemours Research delivers our promise by working every day to create a culture
Dr. Terri H. Finkel,
$74 million to
EDUCATION
of inquiry, evidence, scholarship and integration between the bench and the bedside, and to the clinic and the
Chair of Pediatrics
Nemours,
HIGHLIGHTS
community. Researchers at Nemours are tackling childhood cancers, medication safety, cardiac surgical
and Chief Scientific
$4 million to NCH
outcomes, diabetes, asthma, genetic conditions, infant mortality and more. We are developing capacity in
Officer, NCH
from federal, non-
Health Care Delivery Science, to shed light on how we can improve the overall patient experience and the
federal, and
long-term well-being of the children we serve. In 2014, enterprise-wide Nemours had 388 federal, non-federal
industry-sponsored
and industry-sponsored research grants and contracts with a combined total budget of $74 million; 236 ($40
grants and
million) in Florida overall; 67 ($4 million) at Nemours Children’s Hospital in Orlando. Nemours has grown
contracts
into one of the country’s leading pediatric health networks, ranking 9th in the nation for NIH research funding
among free-standing children’s hospitals. In addition, Nemours’ partnerships with the Community are
fulfilling the NIH mandate for that highest level of Translational Research, dubbed “T4”, in which
investigators study the factors and interventions that influence the health of populations, and ultimately
result in improved global health.
*2014-2020
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MEDICAL CITY PARTNERS INFORMATION
NEMOURS CHILDREN’S HOSPITAL & THE NEMOURS FOUNDATION
PRIMARY CONTACT
FUNDING*
RESEARCH &
The Nemours Center for Endocrinology, Diabetes, and Metabolic Disorders has conducted numerous clinical
Dr. Nelly Mauras,
Over $12 million
EDUCATION
trials, Phase II-IV, studying effects of hormones, growth, and metabolism on diabetes in children and young
Division Chief,
from federal, non-
HIGHLIGHTS
adults. Sponsors have included the NIH, JDRF, AstraZeneca, the Thrasher Research Fund, Genentech,
Endocrinology
federal, and
(CONT’D)
Novartis, Pfizer, Novo Nordisk, Eli Lilly, Medtronic, Merck, and GlaxoSmithKline. In September 2014, the
industry-sponsored
Center secured a 5-year $10 million multi-site grant from the National Institute of Child Health and Human
grants and
Development for the project entitled, “Type I diabetes and the brain in children: metabolic interventions.”
contracts
Included in the research team are collaborators from Nemours, Stanford, Yale, Washington University and
University of Iowa.
The Nemours Oncology Research Laboratory develops novel treatment paradigms to promote healing and
Dr. Tamarah
$120,000
tissue regeneration in multiple tissues by modulating the inflammatory response, the composition of the
Westmoreland,
from FHTCC
extracellular matrix, and the progenitor cell content. This effort is supported by a joint Nemours/UCF
Surgeon, NCH
research agreement with funding from the Florida High Tech Corridor Council. The Oncology lab is also
engaged in a collaborative agreement with Sanford Burnham Prebys Medical Discovery Institute to support
research on the regulation of the gene MYCN in MYCN-amplified advanced neuroblastomas.
The Nemours Center for Pharmacogenomics and Translational Research includes the Asthma Clinical
Dr. John Lima,
$4,096,159
Research Center; Center for Pharmacogenetics; Core Clinical Research Program; and the Nemours Asthma
Associate Director of
from ALA, NIH,
Research Program (including Comparative Effectiveness and Outcomes Research, Sickle Cell Disease-Related
Clinical Research,
NHLBI, FLDOH
Asthma and Lung Disease, Obesity-Related Asthma and Lung Disease, and the Impact of Nutrition on
Nemours Research
Asthma.
Institute, NCH
Dr. Jason Lang,
Center Director, NCH
The Nemours Center for Cancer and Blood Disorders (NCCBD) focuses on developmental therapeutics
Dr. E. Anders Kolb,
$16 million
targeting the unique genetic events that result in pediatric cancers. The NCCBD recently secured a 5-year
Director, Blood and
from NIH
$10.2 million NIH Center of Biomedical Research Excellence grant to establish a Comprehensive Sickle Cell
Bone Marrow
Research Center, and our HTS & Drug Discovery Lab was awarded a $1 million RO1 for assay development
Transplant Program
to discover new inhibitors of NSD1 methyltransferase for pediatric AML.
Dr. Eric Sandler,
Chief, Division of
Hematology/Oncology
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MEDICAL CITY PARTNERS INFORMATION
NEMOURS CHILDREN’S HOSPITAL & THE NEMOURS FOUNDATION
PRIMARY CONTACT
RESEARCH &
The NCCBD strives to maximize our most precious resource: the clinical trial-eligible pediatric cancer
Dr. Andrew Napper,
EDUCATION
patient. Nemours became a new Community Clinical Oncology Program (CCOP) just 18 months ago. The
Director, HTS & Drug
HIGHLIGHTS
mission of the Nemours CCOP is to ensure that each child and young adolescent within our catchment areas
Development Lab
(CONT’D)
FUNDING*
has the opportunity to participate in national cancer prevention, control and treatment trials as appropriate
to his/her background and need. The Nemours NCORP will continue the Nemours CCOP mission and success
with further implementation of systems supportive of Cancer Care Delivery Research and robust quality
management. Nemours recently secured a 5-year $4.65 million grant from NIH to support NCORP
Dr. Tim Bunnell,
$17 million over 5
Nemours is sharing in a $17 million dollar Patient-Centered Outcomes Research Institute (PCORI) grant,
Director of
years from PCORI
partnering with the leading and largest children’s health systems in the nation to transform pediatric health
Bioinformatics
to PEDSnet
care across the United States. Representing more than 5% of the U.S. pediatric population, the PCORI grant
Dr. Terri Finkel, Chief
partners
partners have created a secure electronic network, dubbed PEDSnet, allowing users to tap into a huge patient
Scientific Officer,
database of existing knowledge for clinical research. PEDSnet offers a platform for the evolution of the
NCH
learning healthcare system to generate new insights that can be turned quickly to application on behalf of the
health of America’s children. PEDSnet was, in fact, born from the IOM Learning Health System Roundtable,
when invited participants decided to collaborate. A PEDSnet-wide study on the effects of early childhood
antibiotics on obesity is in progress.
Dr. David Milov,
NemoursOne is a robust, comprehensive, fully integrated and operational electronic health record (EHR)
Chief Medical
system which has been recognized by Healthcare Information and Management Systems Society (HIMSS)
Information Officer,
Analytics with its Stage 7 Award. This highest stage represents an advanced patient record environment.
NCH
Nemours is the first pediatric health institution in the U.S. to achieve HIMSS Stage 7.
Both of our Hospitals have been named to the 16th annual Hospital and Health Networks magazine 2014
Most Wired list. “Most Wired” acknowledges excellence in the use of information technology in four key areas:
infrastructure; business and administrative management; clinical quality and safety; and clinical integration.
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MEDICAL CITY PARTNERS INFORMATION
NEMOURS CHILDREN’S HOSPITAL & THE NEMOURS FOUNDATION
PRIMARY CONTACT
FUNDING*
RESEARCH &
In light of studies indicating that returning military physicians may show a loss of certain clinical skills, the
Dr. Tim Wysocki,
$3.9 million from
EDUCATION
Department of Defense awarded Nemours a $3.9 million grant to evaluate how physicians can maintain these
Director, CHDS
DoD
HIGHLIGHTS
skills. Using Nemours’ comprehensive electronic medical record system, researchers will compare best
Healthcare delivery science (HDS) examines the variables that influence how the right care is delivered to the
Dr. Anne Kazak &
$1 million
right patient at the right time. Embracing this concept for a rapidly changing and value-driven health care
Dr. Tim Wysocki,
from federal grants
economy, Nemours has expanded its Center for Healthcare Delivery Science by bringing aboard a new co-
Directors, CHDS
(CONT’D)
practices to actual care decisions based upon how often a condition is seen. Ultimately, the study will test
decision support interventions, such as feedback alerts in the electronic medical records, benefiting military
and civilian physicians alike.
director, forming a 13-member scientific advisory board, and adding to its research staff. The Center’s vision
is to be recognized as one of the nation’s premier models of integration of HDS research, training, clinical
application, mentoring and external collaboration.
Nemours’ investment in education and training of health professionals makes it one of the largest virtual
Dr. Heather Fagan,
classrooms in the nation. In 2014, Nemours invested $4.5 million to support education and training for 503
Vice-Chair of
medical students, 717 residents, 87 fellows and 1,200 nursing students. Nemours has affiliations with
Education, NCH,
Jefferson Medical College, Mayo Medical School, and the Colleges of Medicine at the University of Florida,
Assistant Dean for
Florida State University and the University of Central Florida.
UME, UCF COM
Nemours offers Continuing Medical Education (CME) for physicians, nurses and health professionals both
Dr. Pamela Arn,
inside and outside of the Nemours system, including national and regional conferences, regularly scheduled
Director of Medical
activities and physician outreach. NemoursEducation.org, Nemours’ free online continuing medical education,
Education
continues to grow. The number of total registered users across the U.S. is more than 76,000.
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MEDICAL CITY PARTNERS INFORMATION
NEMOURS CHILDREN’S HOSPITAL & THE NEMOURS FOUNDATION
PRIMARY CONTACT
SPACE &
Nemours Children’s Hospital (NCH) has access to excellent laboratory space and core resources both within
Cyril Doucet
FACILITIES
NCH and within the outstanding research facilities of its Medical City Partners:
Director of Research
DEVOTED TO

RESEARCH
NCH has a fully equipped General Clinical Research Center (GCRC) on the
4th
floor of NCH,
FUNDING*
Operations
supported by dedicated clinic rooms and inpatient rooms as required for research studies, and with
Nemours Research
additional space for equipment, supplies, staff and other resources. (In addition, NCH also
Institute, NCH
maintains a General Clinical Research Center (GCRC) at NCH’s Clinic at 1717 Orange Avenue in
Dr. Kamran
Orlando for patients visits at that Clinic.) The research effort is supported by the Pathology
Badizadegan, Chair of
Department, whose resources include state-of-the-art testing facilities and the recently established
Pathology, NCH
Nemours-UCF COM Roche Molecular Center of Excellence, designed to accelerate and expand
molecular diagnostics testing.

NCH leases over 3,000 sq. ft. of laboratory and office space for its biomedical research projects
located at the Sanford Burnham Medical Research Institute. Our research efforts are enhanced by
Sanford-Burnham’s advanced technology platforms, including ultra-high-throughput small-molecule
screening, disease model phenotyping, metabolomics, genomics, medicinal chemistry and
pharmacology.

NCH also leases over 4,000 sq. ft. of laboratory and office space at the UCF College of Medicine’s
Burnett School of Biomedical Sciences. With ample room to expand its activities as necessary, NCH
houses its Offices of Clinical Research and Sponsored Projects. Nemours’ efforts are also augmented
by UCF’s strengths in nanotechnology, simulation, chemistry, engineering, optics and photonics.
The NCH research effort is fully integrated as part of the Nemours Research Institute, with activities at its
four locations: Orlando, Jacksonville, Pensacola and Wilmington (Delaware). This provides NCH with direct
access to outstanding services, facilities, faculty and staff located throughout the Nemours Children’s Health
System.
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MEDICAL CITY PARTNERS INFORMATION
NEMOURS CHILDREN’S HOSPITAL & THE NEMOURS FOUNDATION
PRIMARY CONTACT
HEALTHY
Nemours Health and Prevention Services’ (NHPS) vision is optimal health and development for all
Mary Kate Mouser,
LIVING
children. We take a population-oriented, multi-sector approach in Delaware, and build on community
M. Ed., Operational
RESOURCES
strengths and resources, to make policy, system and environmental changes where children and families live,
Vice President,
learn, play, worship and seek healthcare. We are committed to working with our partners to transform
Nemours Health &
communities and health care delivery systems that will improve population health.
Prevention Services
Nemours Center for Children’s Health Media (KidsHealth) is a national leader in the creation of engaging,
Dr. Neil Izenberg,
family-friendly health media and tools that educate and motivate families – while helping care-providers to be
Operational Vice
more efficient and effective. Among its many widely-known products is KidsHealth.org, the #1 most-visited
President, NCCHM;
site devoted to children’s health and parenting in both English and Spanish. On a typical weekday, about one
Madeleine Boyer,
million parents, kids, and teens turn to KidsHealth.org for expert advice and answers. KidsHealth’s
Chief Marketing
physician-led staff consists of clinician-educators, health and science editors, graphic and web designers,
video producers, business developers, and technologists. The Center works with, and licenses private-labeled
FUNDING*
Officer, NCCHM
educational products (including online content, patient instructions, educational videos, text and newsletter
series, and other communication tools) to 80 of the nation’s children’s hospitals and hundreds of media,
governmental, educational, and consumer product companies. KidsHealth also creates KidsHealth in the
Classroom, a free website for educators featuring standards-based health curricula, activities, and handouts.
The Nemours Florida Prevention Initiative works with the community to share healthy lifestyle messages
Dr. Lloyd N. Werk,
with children and families. Targeted health promotion and disease prevention programs help child care
MPH, Division Chief,
providers, educators, health professionals, and community advocates teach children and their families
General Pediatrics,
positive health habits that can last a lifetime.
NCH
Established in 2008, Nemours National Office of Policy and Prevention promotes optimal health and well-
Debbie I. Chang,
being for all children, not only children served within the Nemours health system. To do this, we work with
MPH, Vice President
stakeholders across Nemours and the country to advocate for federal policy change and identify, promote and
of Policy & Prevention
grow innovative practice and population-level solutions within and outside Nemours, advancing clinical care
and community-based prevention efforts. The Nemours Health System also provides us with a laboratory in
which to test new and innovative models, which informs our national policy and practice work. Through this
work, we serve as a trusted resource and voice for children nationally.
7
Nemours BrightStart! researches, develops and offers evidence-based tools targeting young children at risk
Dr. Laura Bailet,
for reading failure, which affects 30 percent or more of our nation’s children. Since BrightStart! began in
Operational Vice
2005, tens of thousands of prekindergarteners have been screened on early literacy skills, with thousands of
President of Nemours
at-risk children receiving Nemours BrightStart! intensive educational instruction.
BrightStart!
Updated 2/2016
MEDICAL CITY PARTNERS INFORMATION
ORLANDO VA MEDICAL CENTER
VISION
PRIMARY CONTACT
We are committed to being a patient-centered integrated health care organization that provides Veterans
excellent health care, research, and education. We strive to be an organization where people choose to
work and an active community partner. We stand as a back-up in responding to national emergencies.
SUMMARY
EMERGING CENTER OF
INNOVATION
The Orlando VA currently employs approximately 3,400 staff at 12 Points of Patient Care across Central
Heather Frebe, Orlando
Florida, who managed more than 1.3 million visits last year. The organization experienced 3% growth in
VA Medical Center Public
enrolled patients in the last year.
Affairs Officer
The Orlando VA Medical Center was designated an Emerging Center of Innovation by the VA Office of
Patient Centered Care and Cultural Transformation. Some transformational activities currently underway
at the medical center include PACT Team Motivational Interviewing, Complimentary (Alternative)
Medicine, Patient Centered Care Hiring, Cooking Demonstrations and Farmers Markets, Patient
Interactive System, Patient Centered Care Concierge Concepts, Real Time Customer Service Data
Collection and Integrated Data Base Construction, Innovative Complaints Management and Service
Recovery Systems, and the Faces of Freedom -- Patient Centered Care Video Project.
COMPREHENSIVE
MEDICAL SERVICES
In addition to services provided through 11 other sites, the new Orlando VA Medical Center in Lake Nona
has a large multispecialty outpatient clinic, 134-inpatient beds, 120-community living center beds, a 60 bed Domiciliary and Mental Health Residential Rehabilitation Program, and administrative and support
services. The first primary care team began seeing patients at the new facility on Feb. 24. Additional
services, including audiology, surgery, interim care, dental care, eye clinic and primary care physicians
have been activated and will continue to roll out in 2016. The new Lake Nona medical campus is a stateof-the-art facility, and has increased accessibility to health care for more than 400,000 Central Florida
veterans.
TELEHEALTH
The Orlando VA Medical Center uses communication and information technologies to provide health care
delivery to Veterans. The term “Virtual Care” means using modern technology to provide clinical care and
patient education when the patient and provider are in separate locations. The Orlando VA Medical
Center uses these technologies to improve Veterans’ access to specialty care and services in VA clinics that
are located closest to their homes. 55,655 Veterans in the Corporate Orlando system were actively involved
in one or more of the five Virtual Care modalities in Fiscal Year 2015.
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MEDICAL CITY PARTNERS INFORMATION
ORLANDO VA MEDICAL CENTER
In 2015, the Orlando VA Medical Center’s research program continued to grow with 53 research projects,
RESEARCH HIGHLIGHTS
PRIMARY CONTACT
18 are ongoing and the remaining are in various preparation stages. We have established collaborations
with the DoD, NIH/NIDDK, academic research institutions including several colleges within UCF,
University of Florida, Tuft University, Vanderbilt Univ., Duke Univ., MD Anderson Cancer Center,
Southwest Oncology Group Consortium, and industry partners. Projects include the VA’s Million Veteran
Program, CONFIRM testing, Lithium treatment in depression, hormone replacement, study of Vitamin D
and Type 2 diabetes, screening and treatment of anal cancer, treatment of plantar fasciitis and many other
disease entities.
THE SIMULATION
LEARNING, EDUCATION
AND RESEARCH NETWORK
(SimLEARN)
The Veterans Health Administration (VHA) SimLEARN National Simulation Center is currently under
construction and will open in Lake Nona in spring 2016. This will be a high-technology, immersive
environment for train-the-trainer activities and the operational hub for coordinating national VHA clinical
simulation activities to meet the local simulation-based training needs of VA medical centers across the
country. The facility will provide a high-fidelity training environment by replicating actual patient
treatment areas in outpatient clinic setting, and inpatient/hospital settings including an intensive care
unit, an operating room and more.
HEALTH CARE FOR
HOMELESS VETERANS
The Orlando VAMC currently has 316 Grant and Per Diem transitional housing beds in its catchment
areas, which includes Brevard, Orange, Volusia, and Osceola counties. Additionally, the OVAMC has
more than 1,000 Veterans currently housed through the U.S. Housing and Urban Development Veterans’
Affairs Supportive Housing Program (HUD-VASH), a majority of which live in the greater Orlando area
and lesser amounts in Titusville, Daytona, and within the Seminole County housing authority. These
services provide permanent supported housing to Veterans and their families. There are 1,200 HUDVASH vouchers allocated to the Orlando catchment area.
Orlando is participating in the 25 Priority Cities Initiatives. As part of this initiative, Orlando VA
Leadership is working closely with community partners to develop a collaborative coordinated assessment.
The goal is aimed at better identifying and matching the “best-fit” housing resources to homeless Veterans.
RESIDENCY PROGRAMS
In 2015 the Orlando VAMC welcomed 16 residents as part of the new internal medical residency training
program. The program is in collaboration with the University of Central Florida Medical School and
Osceola Regional Medical Center, and can accommodate up to 20 residents per year.
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MEDICAL CITY PARTNERS INFORMATION
UNIVERSITY OF CENTRAL FLORIDA COLLEGE OF MEDICINE
VISION
The University of Central Florida College of Medicine aspires to be the nation’s premier 21st century college of
medicine.
PRIMARY CONTACT
Deborah C. German, MD,
Vice President for Medical
Affairs and Dean
The UCF College of Medicine will be a national leader in education, research, and patient care, recognized for
supporting and empowering its students and faculty to realize their passion for discovery, healing, health, and life,
and for its ability to create partnerships to transform medical education, health care, and research.
EDUCATION

Provides biomedical and M.D. educational programs for UCF, the nation’s second largest university.

Over 3,000 undergraduate students studying biomedical sciences, including a new biomedical engineering
program.

Graduate Program consisting of Ph.D. and M.S. students in biomedical sciences

First M.D. class graduated in May 2013. In 2016 - 2017, the M.D. program will be at full enrollment, training
480 medical students per year.

Richard Peppler, Ph.D.,
Associate Dean, Faculty and
Academic Affairs
Griffith Parks, Ph.D.,
Director, Burnett School of
Biomedical Sciences
97 percent of medical students who graduated in the past three years matched into top residency
programs across the state and country.

Combined MD-PhD program trains physician scientists in a multidisciplinary setting.

ACGME-accredited Internal Medicine residency program developed in collaboration with Orlando VA
Diane Davey, M.D.,
Assistant Dean, Graduate
Medical Education
Medical Center and Osceola Regional Medical Center which currently has 34 trainees. New
partnership with Hospital Corporation of America will add 550-plus residency slots in Florida.

Health Explorers and Leaders (HEAL) pipeline program helps prepare underserved middle and high school
students for future health careers.

More than 2,200 volunteer and affiliated faculty physicians.

Global health initiatives include an annual Global Healthcare Forum, and interdisciplinary teams perform
medical mission trips to the Dominican Republic annually.

The student-run KNIGHTS (Keeping Neighbors in Good Health Through Service) in collaboration with Grace
Medical Home provides clinical care to Orlando’s underserved.

The Clinical Skills and Simulation Center uses simulation as a clinical education and treatment tool,
partnering with the Orlando VA Medical Center and others and leveraging the region’s $3 billion modeling
and simulation industry resources. The college’s simulation resources model new approaches to health care
Juan Cendan, M.D., Chair,
Medical Education, Assistant
Dean of Simulation
delivery and patient engagement.

The state-of-the-art Anatomy Lab includes larger-than-life medical imaging of hearts, livers and kidneys,
touch-screen HD monitors and a table that displays a high-definition virtual cadaver that can show every
anatomical system from a full body to individual nerves.
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MEDICAL CITY PARTNERS INFORMATION
UNIVERSITY OF CENTRAL FLORIDA COLLEGE OF MEDICINE
UCF Health, the College’s multispecialty physician practice began treating patients in November 2011 at a facility
PATIENT CARE
blocks from the main UCF campus. The practice opened its second location in Medical City in March 2015 and in
spring 2016 will open an on-site clinic for employees of the Osceola County Sheriff’s Office and their dependents.
All UCF Health physicians are faculty at the medical school.
Members of the Departments of Medical Education, Internal Medicine and Clinical Sciences practice medicine in a
variety of clinical settings across the community.
PRIMARY CONTACT
Edward Ross, M.D.,
Chair, Department of
Internal Medicine, and
Interim Associate Dean
for Clinical Affairs
Diane Davey, M.D.,
Interim Chair, Clinical
Sciences
Clinical Directions:

Be a catalyst for transforming healthcare in collaboration with local and national partners; develop, test
and implement new approaches to delivering efficient, effective high quality care and improving
population health.

Establish innovative, patient-centered, technology-rich clinical education and research programs and
facilities at the UCF Health Sciences campus at Lake Nona.

Partner with others across Central Florida to address fragmentation and enable coordinated, seamless
care.
RESEARCH
The College’s Burnett School of Biomedical Sciences (BSBS) focuses its research on:

Cancer – faculty are creating innovative models for studying tumor growth, metastasis of human
cancers, and anticancer therapeutic agents that target DNA and kill tumor cells

Cardiovascular Disease – Areas of focus include topics such as elucidation of molecular/cellular signaling
events that control heart development and the application of stem cell therapies for treatment of
ischemic heart disease

Sampath Parthasarathy,
Ph.D., Associate Dean for
Research
Griffith Parks, Ph.D.,
Director, Burnett School
of Biomedical Sciences
Neurodegenerative Disease – Research includes biology of demyelination and potential treatment options
for Parkinson’s disease and neurological disorders including ALS (Lou Gehrig’s disease) and Alzheimer’s
disease.

Infectious Disease – Novel therapies are being developed at BSBS to understand, diagnose, and treat
diseases such as Lyme disease, malaria, and tuberculosis, as well as the immune response to microbial
infections.
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MEDICAL CITY PARTNERS INFORMATION
UNIVERSITY OF CENTRAL FLORIDA COLLEGE OF MEDICINE

Medical school has more than 200 research partnerships across the globe.
RESEARCH (CONT’D)

PRIMARY CONTACT
Medical education research programs focus on medical simulation, assessment, professionalism, humanism
and interprofessional education.

100 percent of M.D. students conduct research as part of the curriculum’s two-year FIRE (Focused Inquiry and
Research Experience) module. FIRE mentors include many community physicians and scientists.

An NIH-sponsored team across three research institutions develops and studies interactive avatars that
simulate physician-patient interactions and present pathology to the learner.

The Office of the Associate Dean for Research spearheads new research programs, initiatives, and avenues for
the college and fosters interdisciplinary collaboration within the College of Medicine, other UCF colleges, and
external partners.
UCF REGIONAL
EXTENSION CENTER
FOR HEALTH IT (REC)
With an $8.6 million federal grant, the College helped more than 2,800 Central Florida physicians implement
Jeanette Schreiber, JD,
electronic health records to improve patient care quality and support transformational new models of health care.
MSW, AVP for Medical
The College’s Regional Extension Center has expanded its services to support patient-centered medical homes,
Affairs, CLO
ICD-10 training, health analytics and data, clinical decision support, advanced meaningful use, and other
initiatives to achieve the triple aim of better quality care, greater population health, and more affordable
healthcare.
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MEDICAL CITY PARTNERS INFORMATION
SANFORD-BURNHAM-PREBYS MEDICAL DISCOVERY INSTITUTE AT LAKE NONA
VISION
PRIMARY CONTACT
Scientists at Sanford Burnham Prebys are committed to translating basic research discoveries into innovative
therapeutics that have a tangible impact on human health.
Scientists in the CMOD are studying the metabolic origins of obesity-related diabetes and its cardiovascular
CENTER FOR
METABOLIC
ORIGINS OF
DISEASE (CMOD)
complications. The Center is supported by extensive shared resources, including the Conrad Prebys Center for
Chemical Genomics, cardiometabolic phenotyping, metabolomics, analytical and functional genomics, medicinal
chemistry, and pharmacology. Through partnerships with clinical and commercial organizations, Center
Daniel Kelly, M.D.,
scientific director
scientists advance laboratory breakthroughs to provide clinical benefit for those suffering from disease.
Researchers study how organs and cells work together to respond to biological and environmental challenges that
INTEGRATIVE
METABOLISM
PROGRAM
lead to the development of metabolic diseases. The program brings together investigators with complementary
expertise in cell and molecular biology, chemistry, and physiology. Since metabolic changes are also fundamental
to many other pathological conditions, the basic principles of the research also provide insight and therapeutic
Timothy Osborne, Ph.D.,
program director
avenues for combating other human diseases.
Scientists conduct research into fundamental and early translational aspects of cardiovascular biology,
physiology, and disease. This research focuses on the intersections of metabolic and cardiovascular diseases,
CARDIOVASCULAR
METABOLISM
PROGRAM
including the interrelated effects of heart and vasculature disease. For example, hypertension, ischemic injury,
and diabetes all lead to pathologic cardiac remodeling that involves myocyte hypertrophy, fibrosis and progressive
ventricular dilatation. Similarly, hypertension, smoking, hypercholesterolemia, and diabetes lead to
Peter Crawford, M.D.,
Ph.D., program director
atherosclerosis. This is especially true in the obese or diabetic patient, given that hypertension and ischemic
heart disease often coexist with inciting metabolic disturbances.
The focus of the Genomic Control of Metabolism program is to dissect and understand the genomic and epigenetic
regulatory mechanisms responsible for proper metabolic control to maintain homeostasis. Institute scientists
GENOMIC CONTROL
OF METABOLISM
PROGRAM
primarily study diseases in adipose tissue, liver, muscle, and immune cells. Particular emphasis is put on
Laszlo Nagy, M.D.,
defining the role of key transcriptional regulatory proteins and nuclear hormone receptors in metabolic processes
Ph.D., program director
at the cellular level, in animal models, and in human disease. Another theme of the program’s research is the
systems-level analysis of metabolic processes using integrated experimental and bioinformatics approaches.
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MEDICAL CITY PARTNERS INFORMATION
SANFORD-BURNHAM-PREBYS MEDICAL DISCOVERY INSTITUTE AT LAKE NONA
CONRAD PREBYS
CENTER FOR
CHEMICAL
GENOMICS
FLORIDA
TRANSLATIONAL
RESEARCH
PROGRAM (FTRP)
The Conrad Prebys Center for Chemical Genomics is Sanford Burnham Prebys Institute’s robotic ultra-highthroughput and high-content screening center for testing large collections of small chemical structures to find
promising drug leads. It is equipped with the most advanced drug discovery technologies in the nonprofit world
and staffed with highly trained scientists, many with years of experience in the pharmaceutical industry.
PRIMARY CONTACT
Layton Smith, Ph.D.,
director, Drug Discovery
Florida
The FTRP is a unique research-collaboration program open to Florida-based scientists. Funded by the Florida
Layton Smith, Ph.D.,
Department of Health, the FTRP strives to produce a pipeline of potential new medicines based on laboratory-
director, Drug Discovery
research discoveries.
Florida
The business development office manages the commercialization of discoveries that result from Sanford Burnham
Prebys research. The business development team is actively engaged in developing relationships with potential
BUSINESS
DEVELOPMENT
partners and funding organizations for the advancement of shared research initiatives. The Intellectual Property
team manages the licensing of technology and material transfers. Our multidisciplinary approach provides
partners with access to custom-designed teams that include academic investigators, clinical researchers, and in-
Leslie Molony, Ph.D.,
senior director, Business
Development
house scientists with extensive pharmaceutical and biotechnology industry experience.
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MEDICAL CITY PARTNERS INFORMATION
UNIVERSITY OF FLORIDA RESEARCH AND ACADEMIC CENTER
VISION
Foster collaboration that stimulates innovative approaches to research and patient care, particularly in the
areas of cancer, cardiovascular disease, diabetes and brain disorders
The Helen and David Bean Campus of the University of Florida, College of Pharmacy in Orlando is located at
ORLANDO COLLEGE OF
PHARMACY
the UF Research and Academic Center in Lake Nona. The facility houses a four-year Doctor of Pharmacy
(Pharm.D.) Program. About 70 new students are accepted each year, with a total of 280 students working to
become licensed pharmacists.
CENTER FOR
PHARMACOMETRICS
AND SYSTEMS
PHARMACOLOGY
PRIMARY CONTACT
Erin St.Onge, Pharm.D.,
Assistant Dean and
Campus Director
The Center conducts applied research proximal to clinical trials and/or clinical practice oriented toward
Larry Lesko, PhD.,
problem solving through quantitative analysis, drug-disease modeling/simulation, and clinical trial design.
Center Director and
Research interests include Cancer, Cardiovascular diseases, Diabetes & Obesity, Orphan drugs, and special
Clinical Professor
patient populations, such as pediatric rare diseases.
Housed within the UF College of Pharmacy, the Center is one of the leading educational institutions in
Larisa H. Cavallari,
CENTER FOR
PHARMACOGENOMICS
pharmacogenomics research and training of future scientists. Investigations include the study of disease-gene
Pharm.D., BCPS,
associations and relevance to pharmacogenomics.
Director
INSTITUTE FOR
THERAPEUTIC
INNOVATION (ITT)
ITT focuses on developing and testing new drugs to treat and cure a variety of infectious diseases caused by
George Drusano, MD
drug-resistant pathogens such as TB and MRSA commonly linked to hospital-acquired infections.
Institute Director
Housed within the UF College of Medicine, the Institute on Aging conducts leads the aging and geriatric
research department clinical research unit which will allow thousands to participate in clinical and
translational research studies aimed at improving the health and independence of older adults.
INSTITUTE ON AGING
(IOA)
Research focuses on mechanisms, etiology, prevention and rehabilitation of cognitive and physical disability.
Among several projects, UF is leading the largest NIH funded study of physical activity lifestyle interventions
to prevent disability in older adults ($86,000,000 project involving over 1,600 older adults throughout the
Marco Pahor, MD,
Director; Professor and
Chair, Department of
Aging and Geriatric
Research
U.S.).
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MEDICAL CITY PARTNERS INFORMATION
UNIVERSITY OF FLORIDA RESEARCH AND ACADEMIC CENTER
PRIMARY CONTACT
The mission of the CTSI is to improve human health by accelerating the translation of scientific discoveries
CLINICAL AND
TRANSLATIONAL
SCIENCE INSTITUTE
(CTSI)
into practical applications and practices for the diagnosis, treatment, prevention and cure of human diseases.
As a catalyst and hub connecting resources, people and ideas, the CTSI expands collaboration and advances
science across UF’s 16 colleges, the state of Florida and the national Clinical and Translational Science Award
Dr. David Nelson,
Director, UF CTSI
consortium.
MEDICATION THERAPY
MANAGEMENT
COMMUNICATION AND
CARE CENTER
(MTMCCC)
The center provides an experiential practice site for fourth-year student pharmacists, allowing them to
perform comprehensive medication reviews via the telephone, complete patient chart quarterly reviews, and
speak to patients regarding adherence issues.
Anna Marie Hall,
Pharm.D., BCACP,
Assistant Director,
MTMCCC
The Florida Minority Cancer Research and Training Center (MiCaRT) is a partnership between UF and
THE FLORIDA
MINORITY CANCER
RESEARCH AND
TRAINING CENTER
(MiCaRT)
Florida A&M University with funding from the National Cancer Institute. The partnership is the only
federally-funded minority partnership focused on cancer research and training for African Americans. The
center launched a Minority Health Behavioral Research Core, which has a lab in Lake Nona, including a
private waiting room, community resource center, focus group room, computer room for surveys, and for
preparing and processing mail surveys. The goal is to train black researchers and support more studies
focused on minority health.
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