82 Chemistry Requirements for a Minor in Chemistry (23 credits) CHM 1010. General Chemistry I (3) or CHM 1510. General Chemistry I, Honors and Majors (3) CHM 1011. General Chemistry I, Laboratory (1) or CHM 1511. General Chemistry I Laboratory, Honors and Majors (1) CHM 1020. General Chemistry II (3) or CHM 1520. General Chemistry II, Honors and Majors (3) CHM 1021. General Chemistry II Laboratory (1) or CHM 1521. General Chemistry II Laboratory, Honors and Majors (1) CHM 2510. Organic Chemistry I (3) CHM 2011. Organic Chemistry I Laboratory (1) or CHM 2511. Organic Chemistry I Laboratory, Majors (1) CHM 2520. Organic Chemistry II (3) CHM 2021. Organic Chemistry II Laboratory (1) or CHM 2521. Organic Chemistry II Laboratory, Majors (1) CHM 3030. Quantitative Analysis (4) One additional 3-credit chemistry elective at the 3000-level or higher. NOTE: Neither BCH 3320 nor CHM 4500 will fulfill this requirement. Course Descriptions BCH 2881, 3881, 4881. Special Topics. Variable credit. May be repeated. BCH/CHM 2990. Research and Writing in Biochemistry. An overview of research methods and scientific writing in the area of biological chemistry that emphasizes critical review of scientific literature, formulation of research problems, design of experiments, collection and recording of experimental data, and presentation of results. Pre-or corequisite: CHM 2520. Course consists of four lecture hours per week and is offered in the spring. Three credits. BCH 3220. Biochemistry I. A study of the chemical and physical properties of proteins, nucleic acids, carbohydrates, and lipids. An introduction to bioenergetics and carbohydrate metabolism. Prerequisite: CHM 2520. Course consists of three lecture hours per week and is offered in the fall. Three credits. BCH 3320. Biochemistry II. A study of the chemical and physical properties of proteins, nucleic acids, carbohydrates, and lipids. An introduction to membrane channels and pumps, the pentose phosphate pathway and the Calvin cycle, photosynthesis, glycogen metabolism, fatty acid metabolism, protein turnover: amino acid degradation and the urea cycle, biosynthesis of amino acids, biosynthesis of nucleotides, biosynthesis of lipids and related molecules, DNA replication and repair, RNA synthesis and splicing, protein synthesis, and integration of metabolism. Prerequisite: CHM 3220 with a grade of C- or higher. Three credits. BCH 3330. Biochemistry Laboratory. Introduction to basic laboratory studies in biochemistry, including protein purification, isolation and characterization of biological molecules, enzyme kinetics studies, chromatography and electrophoresis of biological macromolecules, and methods of quantitative analysis. Pre- or corequisite: CHM 3220. Course consists of three laboratory hours per week and is offered in the spring. One credit. BCH 4150. Biophysical Chemistry. A study of the physical chemistry of biological macromolecules (proteins, DNA, lipids, and carbohydrates), with emphasis on thermodynamics of molecular structure and function, physical and spectroscopic assessment of conformational changes of macromolecules, kinetics and equilibrium in biochemical systems, and statistical thermodynamics of molecular ensembles. Prerequisites: BCH 3220, MTH 1420, and PHY 2020. Course consists of three lecture hours per week and is offered in the fall. Four credits. BCH 4160. Physical and Analytical Biochemistry Laboratory. Laboratory studies of the physical and analytical chemistry of biological macromolecules, including calorimetry; biochemical assay development 26 for the detection of biological target compounds; advanced biomolecular separation and characterization techniques; spectroscopic studies of proteins, DNA, and lipids; and advanced studies of enzyme kinetics and equilibrium processes. Pre- or corequisite: BCH 4150. Course consists of three laboratory hours per week and is offered in the fall. Two credits. BCH 4444. Independent Study. Individual study and research under the guidance of a member of the department. One to four credits each semester. BCH 4810-4815. Student Internship. Three, four, six, eight, ten or twelve credits. CHM 1000. The World of Chemistry. A study of the basic concepts of chemistry and their relationship to the everyday “Every great advance in science has issued from a new audacity of the imagination.” – John Dewey Chemistry experiences of humankind. Laboratory exercises emphasize the demonstration of chemical principles and the properties of materials encountered in everyday life. Course consists of 3 class hours and 1 – 3 laboratory hours per week. This course is recommended for the non-science major who seeks a single semester course. Four or six credits. [N] CHM 1010. General Chemistry I. Matter is examined by a study of the atom, compounds, chemical nomenclature, formulas, the periodic table, and chemical reactions. Other topics include the gas Laws, Lewis structures, and thermochemistry. Corequisite: CHM 1011. Course is offered in the fall. Three credits. [N] CHM 1011. General Chemistry I Laboratory. This course consists of a series of laboratories which reinforce the concepts being studied in CHM 1010. In addition to learning problem solving and critical thinking skills, students will be introduced to laboratory safety and gain hands-on experience using a variety of laboratory equipment and techniques. Corequisite: CHM 1010. Course is offered in the fall. One credit. CHM 1020. General Chemistry II. Matter is examined by a study of the atom, compounds, chemical nomenclature, formulas, the periodic table, and chemical reactions. Other topics include kinetics, chemical equilibria, acids and bases, coordination chemistry, chemical thermodynamics, electrochemistry, nuclear chemistry, and organic chemistry. Prerequisite: CHM 1010 with a grade of C- or higher. Course is offered in the spring. Three credits. CHM 1021. General Chemistry II Laboratory. This course consists of a series of laboratories which reinforce the concepts being studied in CHM 1020. In addition to learning problem solving and critical thinking skills, students will be introduced to laboratory safety and gain hands-on experience using a variety of laboratory equipment and techniques. Prerequisite: CHM 1011 with a grade of C- or higher. Corequisite: CHM 1020. Course is offered in the spring. One credit. CHM 1510. General Chemistry I, Honors and Majors. Matter is examined by a study of the atom, compounds, chemical nomenclature, formulas, the periodic table, and chemical reactions. Other topics include the Gas Laws, Lewis structures, and thermochemistry. Course is offered in the fall. Three credits. [N] CHM 1511. General Chemistry I Laboratory, Honors and Majors. This course consists of a series of laboratories which reinforce the concepts being studied in CHM 1510. In addition to learning problem solving and critical thinking skills, students will be introduced to laboratory safety and gain hands-on experience using a variety of laboratory equipment and techniques. Corequisite: CHM 1510. One credit. CHM 1520. General Chemistry II, Honors and Majors. Matter is examined by a study of the atom, compounds, chemical nomenclature, formulas, the periodic table, and chemical reactions. Other topics include kinetics, chemical equilibria, acids and bases, coordination chemistry, chemical thermodynamics, electrochemistry, nuclear chemistry, and organic chemistry. Prerequisite: CHM 1510 with a grade of C- or higher. Course is offered in the fall. Three credits. CHM 1521. General Chemistry II Laboratory, Honors and Majors. This course consists of a series of laboratories which reinforce the concepts being studied in CHM 1520. In addition to learning problem solving and critical thinking skills, students will be introduced to laboratory safety and gain hands-on experience using a variety of laboratory equipment and techniques. Prerequisite: CHM 1511 with a grade of C- or higher. Corequisite: CHM 1520. One credit. CHM 1616. Forensic Chemistry. This course uses the field of forensic chemistry to illustrate chemical concepts. We will introduce the fundamental principles of chemistry that require conceptual and mathematical problem solving skills. Course consists of two class hours and two laboratory hours per week, and is recommended for the non-science major who seeks a single semester course. Four credits. [N] CHM 2011. Organic Chemistry I Laboratory. Laboratory work includes characterization, extraction, chromatography and distillation of organic compounds, preparation of typical compounds, a study of their reactions, and the qualitative identification of unknown substances. Microscale procedures will be used for the majority of the exercises. Instrumental analytical procedures are included. Prerequisites: CHM 1020 and CHM 1021; pre-or corequisite: CHM 2510. Course consists of two laboratory hours per week and is offered Fall. One credit. CHM 2021. Organic Chemistry II Laboratory. Laboratory work includes extraction chromatography and distillation of organic compounds, preparation and characterization of typical compounds by chromatographic and spectroscopic techniques. Microscale procedures will be used for most of the exercises. Prerequisites: CHM 2011 and CHM 2510; preor corequisite: 2520. Course consists of two laboratory hours per week and is offered in the spring. One credit. 83 The mission of High Point University is to deliver educational experiences that enlighten, challenge, and prepare students to lead lives of significance in complex global communities. 84 84 Chemistry Chemistry & Physics CHM 2510. Organic Chemistry I. A comprehensive study of organic compounds stressing electronic valence theory. Bonding, nomenclature, acidity and nomenclature are covered. Reaction mechanisms, nucleophilic substitution mechanisms, alkene and alkyne chemistry, infrared spectroscopy. Prerequisite: CHM 1020 or 1520 with a grade of C- or higher. Three credits. CHM 2511. Organic Chemistry I Laboratory, Majors. Introduction to unit laboratory processes for synthesis, purification and characterization organic molecules. Both micro-and macro-synthetic procedures will be utilized. Purifications will utilize separations by extraction, distillation and/or chromatography at the synthesis scale. Inert atmosphere, steam volatilization and low pressure distillations techniques will be used. Both high pressure liquid chromatography and gas chromatography will be used. Characterization will be by determination of physical properties such as melting and boiling ranges, refractive index, optical activity and spectroscopic characterization especially infrared, C 13 and H1 nuclear magnetic resonance and mass spectroscopy. The laboratory notebook and safety in the chemistry laboratory will be emphasized. There will be a weekly recitation period required. Prerequisite: Chemistry 1511. Corequisite: CHM 2510. Course consists of six laboratory hours per week and is offered in the fall. One credit. CHM 2520. Organic Chemistry II. A comprehensive study of organic compounds stressing electronic valence theory. Nuclear magnetic resonance, the synthesis and reactions of alcohols and ethers, nucleophilic substitution and addition at the carbonyl group, electrophilic aromatic substitution, the synthesis and reactions of amines, and pericyclic reactions. Prerequisite: CHM 2510 with a grade of C- or higher. Three credits. CHM 2521. Organic Chemistry II Laboratory, Majors. An introductory course in research methods for the chemical sciences that emphasizes selection of a research problem, the chemical literature, design of experiments, analysis of data, and presentation of results. There will be a weekly recitation period required. Prerequisites: CHM 2510 and CHM 2511. Corequisite: CHM 2520. Course consists of six laboratory hours per week and is offered in the spring. One credit. CHM 2881, 3881, 4881. Special Topics. Variable credit. May be repeated. CHM 3030. Quantitative Analysis. The theory and technique of chemical separations, volumetric, gravimetric, and colorimetric methods. Prerequisites: CHM 1520 and 1521. Course consists of two class hours and six laboratory hours per week, and is offered in the fall. Four credits. CHM 3060. Instrumental Analysis. The theory and practice of spectroscopic, electroanalytical, and chromatographic instrumental analytical techniques. Prerequisites: MTH 1410, CHM 2520, and CHM 3030. Course consists of three class hours and six laboratory hours per week, and is offered in the spring. Five credits. CHM 3110. Inorganic Chemistry. A study of the systematic chemistry of the elements. Emphasis is placed on electronic structure and bonding. Other topics covered may include “warm” superconductors, transition metal carbonyls, organometallic compounds, nitrogen fixation, and metal-containing molecules of biological importance. Prerequisite: CHM 2520 and CHM 2521. Course is offered in the fall. Three credits. CHM 3111. Advanced Topics Lab. This course is a combined lecture/laboratory course that will provide fundamental concepts related to current experimental techniques in chemistry and focusing on performing related experiments in the laboratory. The goal of this interdisciplinary course is to allow students to plan and conduct original research on a topic of their choosing. Multiple faculty members will assist students in this course throughout the semester by lecturing on specific topics and instrumentation that can assist students in performing this research. As a three-credit course, a typical week in class will consist of one to two lectures and then lab time to implement techniques discussed in lecture. Three credits. Chemistry CHM 4010. Elements of Physical Chemistry. A study of the theoretical aspects of chemistry, with emphasis on chemical thermodynamics, electrochemistry, and chemical kinetics. Prerequisites: MTH 1420, CHM 1020, and PHY 1520 or PHY 2020. Course is offered in the fall. Three credits. CHM 4011. Laboratory in Physical Chemistry. The determination of physical properties and thermodynamic properties of matter and kinetic studies. Prerequisite: CHM 4010. Course consists of three laboratory hours per week. One credit. CHM 4020. Advanced Topics in Physical Chemistry. A study of quantum chemistry, chemical dynamics, statistical thermodynamics, and molecular structure. Prerequisites: CHM 4010. Course is offered in the spring. Three credits. CHM 4444. Independent Study. Individual study and research under the guidance of a member of the department. One to four credits each semester. CHM 4500. Research in Chemistry and Biochemistry. Chemistry 4500. Research in Chemistry and Biochemistry. A study of a basic research problem to be determined in consultation with the chemistry faculty. A formal research proposal is required. Work on the problem may extend over more than one semester and will culminate in a formal research presentation and paper. Course consists of six laboratory hours per week. May be repeated. One to three credits per semester. CHM 4810-4815. Student Internship. Three, four, six, eight, ten or twelve credits. CHM 4990. Senior Seminar in Chemistry and Biochemistry. A thorough introduction to the chemical literature. A literature review paper will be written and presented. This course must be taken by students taking the B.S. in Chemistry, B.S. in Biochemistry and the B.A. in Chemistry. Prerequisite: senior standing in chemistry or biochemistry. Course is offered in the spring. One credit. NSC 2100. Physical Science for Education. An inquirybased study of the basic concepts of physical sciences, including properties of matter, motion and forces, and electricity and magnetism. Laboratory work emphasizes the application of the scientific method to understanding physical reality. This course is restricted to education majors and consists of 6 hours of integrated lecture and lab per week. Course is offered in both the fall and spring. Four credits. [N] NSC 2200. Earth Science for Education. An introduction to fundamental processes of Earth. Topics include the theory of plate tectonics, rocks and minerals, formation of the continents, mountains and oceans, the atmosphere and pollution, natural resources, and basic astronomy. This course is restricted to education majors and consists of 6 hours of integrated lecture and lab per week. Course is offered in both the fall and spring. Four credits. [N] 85