What lasers can make you blind by Lars Hode Swedish Laser-Medical Society • Background: Since 40 years, there are special rules and restrictions i i for f the h use off certain i lasers. l The reason is that some laser types, sometimes are able to cause eye injury, also at distance distance. What can happen if you by mistake look into a strong laser beam? If you can cut in steel, steel then you can destroy an eye. How dangerous are actually t ll different diff t llasers?? The classification of lasers is almost the same everywhere in the world, but the rules concerning use of lasers and rules for permission and registration of instruments is very different. E.g. E g in Sweden class 4 lasers for hair removal removal, for tattoo removal, for wrinkle treatment etc, are completely o p e e y free ee ssince e five e yea years. s In most os countries ou es you need a doctor behind you and in other countries the doctor has to be the therapist. Many people think that looking into a laser beam can make them blind. Is that correct? Yes, there are such lasers! I will describe Yes some of them and show examples. 10 meter 6 MW output Weight 20 ton Output power 6 mW 10 mm Weight 2 gram This laser, a laser diode, often used in a therapeutic p laser instrument. This laser can not harm you. It can possibly heal an injured eye! This laser was never produced. But it is p possible to make it, if enough money is available. It was constructed theoretically under Richard M. Nixons administration in USA and about 20 units was thought to circulate in satellites around the earth. The intention was to burn Russian nuclear missiles when they came up through the atmosphere. This laser could make you blind. blind Before One week later Two months later This fibroma was removed with a 15 watt surgical CO 2 laser, 50 mm focal length. Can that laser make you blind? NO. It might burn the cornea in or near the focal area, but not make someone blind! An Alexandrite laser for hair removal. Can this laser make you blind? NO These lasers can make you blind But they are very expensive expensive, very heavy and takes a lot of kilowatts to run This laser can make yyou blind Price: 380,000 € A Q-switched Nd:YAG-laser – can it make you bl d iff someone shoots blind h right h into your eyes? NO Dart arrows ... Price: 2.50 € ... can make an eye blind Ear protection E t ti must be worn too! A slingshot can make you blind. It can be used by anyone older than 5. It is very cheap. You don’t need a responsible doctor ..... No comments ! ! ! Bullet proof vest must be worn. It would be much safer if it was a class 4 laser; they might cause an injury but they can’t injury, make you blind. Other laser risks High voltage Warning! High voltage capacitors are ridiculously dangerous things. They can store enough energy to kill you instantly. Retina injured j byy strong laser pulses. Is the person blind? No Now, a few words about the risk factors. A laser is a lamp. There are many types of lamps. The light from a laser has always two properties: • It has one wavelength – very narrow bandwidth • It is highly coherent (well organized, very “pure”, pure , in the same way as the tone from a flute is more pure than the sound of a jet plane). Are these two factors making laser light dangerous? No Further,, much stronger g lasers are used in the following eye treatments: Laser trabeculoplasty for open angle glaucoma Laser iridotomy in pigment dispersion syndrome Laser photocoagulation for neovascular age-related macular degeneration Photodynamic Therapy of wet macular degeneration L Laser assisted i t d in i situ it keratomileusis k t il i (LASIK) for f myopia i correction ti Laser treatment of diabetic retinopathy Laser treatment of solar retinopathy Laser treatment of age related macular degeneration Lasering drusen Treatment of keratoconjunctivitis with LLLT Correction of myopia (PRK) and astigmatic keratotomy (AK) Laser in transpupillary thermotherapy (TTT) Laser photolysis of cataract Laser welding of the cornea Laser posterior capsulotomy …. and some other treatments Also, it is not "laser" light that may be dangerous. It iis any light li ht off certain t i power, and d exposure time, ti in i certain wavelength interval, with certain pulse energy (if pulsed) pulsed), with certain geometric configuration (divergence, solid angle) etc that may cause such irradiation in the retina that the MPE (maximum ( permissible exposure) is exceeded much enough. Examples E l off such h light li ht sources are IPL, IPL strong t flash fl h lamps, certain xenon arc lamps. What Wh t iis the th best b t protection? t ti ? Knowledge. Safety glasses can be hazardous: If you use the wrong type, you may think that you are protected, but instead ... Coherency Coherency has nothing to do with parallelism. It is often said th t iin laser that l light, li ht the th waves are in i phase h with h each h other, h but b that h is only l true inside the laser cavity. After the light has left the laser, this statement is wrong. This picture is showing light of long coherence length – laser light ... ... and ... picture shows light g with ... this p shorter coherence length monochromatic ”ordinary light”. Other p properties, p , like parallel p beam,, high g power may be at hand with some lasers. Most lasers are not strong. Most lasers emit the light in a divergent beam. Then, what makes some lasers dangerous? There are certain risk factors, which? Summary of risk factors 1. High g p power 2. Long exposure time 3. Parallel beam 4. Not visible wavelength 5. Small beam diameter 6 Extreme pulsing (e 6. (e.g. g Q Q-switching) switching) 1. Extended source / several sources decreases the risk. Narrow beam - one of the risk factors A wide beam is less hazardous to an eye than a narrow beam because only a fraction passes through the pupil, the rest comes outside. Classification of lasers – laser classes Parameters: Laser type Wavelength O t t power Output Divergence Extended source Pulsing The classification of lasers is one of the procedures that are included in the so called CE-approval containing a lot of international standards. A classified l ifi d llaser will ill b belong l tto one off th the groups 1 – 4. 4 1, 2, 3A, 3B, In Sweden, lasers in these groups are free to use. 4 Doctor or dentist An eye is working like a digital camera where the retina is a detector matrix with millions of pixels in the form of light sensitive cells. When these cells are hit by visible light, they are producing a nerve signal. signal From this signal signal, our brain is building up an image image. eye lid The eye muscle sclerotic coat choroid retina iris pupil optic nerve cornea fovea ( ll (yellow spot) aqueous humour sclera muscle A parallel ll l b beam iis d depicted i t d att th the retina ti as a smallll point. i t Wh When llooking ki against i t th the sun, the image will be a picture of the sun with sun spots and all. In the case of an unpleasant intensity, our blink reflex is ”switching off”, first by blinking then by turning your head. Waveleng g th as risk factor Different risk i k llevels l in different parts of the spectrum. Therapeutic lasers ... ... are practically risk free. Fear of lasers cause more problems than the lasers themselves do. Therapeutic lasers are usually in the power region 1 - 500 mW. Nobody, ... yes, nobody has become blind from a laser. Anyy laser. Therapeutic lasers can cure many eye diseases di Low-Level Laser Therapy Improves Vision in Patients with A R l t d Macular Age-Related M l Degeneration D ti Boris T. Ivandic, M.D., and Tomislav Ivandic, M.D. Results: LLLT significantly improved visual acuity (p 0.00001 versus baseline) iin 162/182 (95%) off eyes with ith cataracts t t and d 142/146 (97%) off eyes without ith t cataracts. The prevalence of metamorphopsia, scotoma, and dyschromatopsia was reduced. In patients with wet AMD, edema and bleeding improved. The improved vision was maintained for 3–36 3 36 months after treatment treatment. Photomedicine and Laser Surgery Volume 26, Number 3, 2008 © Mary Ann Liebert, Inc. Pp. 241–245 Conclusion: Lasers are of extremely low risk compared to: Dart arrows. Air guns. guns Knives. Stones thrown. Slingshots. Practically all weapons. B k b Broken branches h on trees t iin the th forest. f t Let us forbid all these things before putting strong restrictions on therapeutic (and surgical) lasers Thanks for listening About lasers and IPL In many beauty salons, salons instruments for permanent removal of hair are used. They are: • • • • Ruby lasers [691 nm] Alexandrite lasers [[755 nm]] Diode lasers [808 nm] Nd:YAG lasers [[1064 nm]] and • IPL instruments [[600 – 1200 nm]] In most countries there are no rules for IPL devices as they are regarded more or less harmless to eyes. How to know if a light source is dangerous? According to IEC and ICNIRP, a limit, MPE (Maximum Permissible Exposure) is given, above which, permanent eye injuries can occur. I have calculated the irradiation levels, both from a laser and an IPL instrument in the retina of a human eye, in order to determine the MPE from light g pulses p directed against g an open p unprotected eye. Ph i l data Physical d t used: d Parameter: Ruby laser IPL device Unit Wavelength Pulse energy Pulse time Aperture Aperture area Divergence *) 694 nm max 8 joule 5 - 15 ms round 0. 0 8 mm in diam. diam 0.5 × 10 -6 m 2 ca 0.125 sr (90%) 615 - 1500 nm max 80 joule ca 25 ms rectangle 10 × 20 mm 2 × 10 -4 m 2 ca 0.4 sr (90%) λ Q t A Ω *) The percentage specifies that 90 % of the energy is within the specified solid angle. R di Radiance L The parameter that decides if a source is dangerous to the eyes is its radiance, radiance L. L • dΦ is the momentary • dΦ dΦ L= dA ⋅ cos θ ⋅ d Ω • • power of the radiation Φ = dQ/dt dA is the surface in front of the pupil pupil. dΩ is the solid angle in direction to the eye θ is the angle between the normal of the aperture and the direction to the eye. The expression for L is valid for every point in the aperture that is depicted on the retina. If the aperture has a certain size that exceeds the vision angular αmin, in view from the eye, the light source is defined as an extended source. αmin depends among other things on the exposure time t. If t < 0.7 seconds, αmin=1.5 mrad. When looking into the laser or IPL aperture at 20 cm distance, the angle, in both cases, exceeds αmin. Wh is When i it i dangerous? d ? The MPE related to the radiance of a source is named L MPE. For extended light sources, the following equation is valid: L MPE ≈ 8.5 85 × 10 3 × H MPE [sr -1 J m -2 ] where H is the exposure according to H = dQ/dA In the expression above H M PE refers to a point source with H MPE = 0.05 0 05 [ J m -22 ]. ] This Thi gives: i L MPE = 425 [[sr -11 J m -22] If the radiance of a light source is fairly equal in all directions over the solid angle Ω, the integrated radiance LP is a function of the power density HA in the aperture: HA = ∫ Ω LP d Ω which, in directions close to the normal, i.e. where cos θ ≈1 and Ω<1 sr can be simplified to: H A = Ω× Ω LP The value of H that may cause damage (H=HMPE) can be hence be written: H MPE = Ω× LMPE [ Jm −2 ] Provided that the radiance is relatively uniform over the area A of the aperture, the pulse energy QMPE is calculated l l d from f the h following f ll i simple i l expression: i Q = ∫ HdA A and QMPE = Ω × LMPE × A [ J ] As can be A b seen, Q MPE is i not dependent d d on the h y and the aperture. p distance between the eye Hence the irradiance in a point in the image on the retina remains constant if the distance between the eye and the aperture is changed. However the area of the image is reversely proportional to the distance squared. An IPL instrument with the parameters in the example above, have the following value of Q MPE : QMPE = 0.4 [sr]×425[sr−1Jm−2]×0.0002[m−2] = 0.034[J] This means that it is safe to look directly into its beam if the pulse energy is less than 0. 0 034 joules. joules With the pulse energy given in the example above above, its pulse energy is more than 2000 times higher than this safe limit. limit • Results: The calculations show that, that if a light pulse from an IPL is fired from a distance of 20 cm against an open eye, eye the energy level can be more than 2000 times higher than maximum permitted exposure exposure. Consequently, either the IPL instruments Consequently can be rather dangerous to human eyes or the internationally used MPE limit needs to reconsider. IPL vs. Laser L Irradia ance L [J/m2] 300,000 × L MPE L MPE Risk for permanent damage 2,000 0.005 L MPE L MPE 2 Image area on the retina × A [mm2] The chosen values of energy density and aperture area in the example, 40 J/cm2 and 2 cm2, are not exaggerated. exaggerated There are instruments with twice as high energy density, according to the manufacturers and then the MPE can be exceeded byy more than a factor 4000. Consequences of an injury There is no doubt that certain lasers can injure the eyes because of their high radiance in the aperture. However, it iis the H th consequence off an iinjury j that th t iis important rather than the fact that the eye is injured. Further calculations show that an injury in the retina, caused by a laser, has a small consequence by means of effects on the vision while, if caused by an IPL instrument,, the injury j y can be of much larger g consequence. Optics p of the eye y Projection of the aperture p on retina Aperture 2 cm 20 cm A small aperture (such as from a laser) is projected to a smallll image on the h retina while h l a large l aperture (such as from an IPL) is resulting in a large image. The consequences of eye injury caused by a laser Visual effect from eye injury at 2 m distance: round spot, 8 mm diam Eye injury by laser from fiber aperture at 20 cm distance. Size of blind spot: 8 mm Fiber Φ 0.8 mm 20 cm Focal spot on retina, Φ 0.08 mm 2m The consequences of eye injury caused by an IPL Visual effect from eye injury at 2 m distance: 10 × 20 cm Eye damage by an IPL shot. Aperture at 20 cm distance. Size of blind area IPL aperture 10 x 20 mm 20 cm Projection on the retina, 1 x 2 mm spot 2m Reported incidents Journal for Ms Xxxx A 41 year old woman was treated on her eyelid (!) with an IPL device. She got iridoirido cyclite and was treated by means of adrenaline pads on the Ullevål hospital in Oslo. At a demonstration of an IPL instrument in an exhibition,, a shot was fired byy mistake because somebody happened to step on the foot pedal. The hand p piece,, with the 1 × 2 cm aperture, p , was placed p in its holder on the side of the instrument, about 80 cm up p from the floor. A hole was burnt in a p persons jacket. j ”M face ”My f was d destroyed” t d” IPL treatment of face. Longitudinal burns. The doctors comments: “the instrument gave more than the setting” • Conclusion: Even though the irradiance level resulting from a laser can be much higher than from an IPL, the levels are are, in both cases, cases high enough to permanently destroy the cells of vision. A beam, beam strong enough to burn a hole in a jacket is naturally dangerous to eyes. • Other considerations: Even though strong lasers may cause eye injury one should bear in mind that every day injury, strong lasers are “fired” right into unprotected open eyes in the treatment of retinopathy, retinopathy macula degeneration, cataract, near-sightness and of some other eye problems. And, this patients blind. does not make the p My recommendations: The IPL instruments can imply p y a great g risk and it is important that there are regulations for them as well as for lasers lasers. Rules for all strong light sources ought to be considered. First of all: Therapeutic lasers are practically risk free. The stronger types (typically class 4) can cause an injury, but they can not make you blind. They are usually in the power region 1 – 500 mW. Fear of lasers cause more problems than the lasers themselves do do.