Nude Mice** –NU/NU STRAIN CODE: 088 (HOMOZYGOUS), 089 (HETEROZYGOUS)§ 1–100 72.45 80.25 90.40 Age in Days* Up to 42 43–56 57–63 64 plus 1–100 84.20 93.40 104.70 MALE QUANTITY AND PRICING 101–250 54.45 62.60 72.75 Price upon request FEMALE QUANTITY AND PRICING 101–250 63.30 73.75 84.25 Price upon request 251+ 45.50 53.40 64.60 251+ 53.00 63.40 74.45 *Estimated age **Outbred, isolator-maintained § Heterozygous (haired) animals are not immunodeficient. Call 1.800.522.7287 for pricing and availability. 50 MEAN WEIGHT +/- 2 STANDARD DEVIATIONS 40 WEIGHT IN GRAMS Age in Days* Up to 42 43–56 57–63 64 plus 30 20 10 Nomenclature Crl:NU-Foxn1nu Origin This immunodeficient nude mouse originated from NIH and was originally thought to be a BALB/c congenic. It was later determined that it was not inbred and is, therefore, maintained as an outbred, and is not associated with any stock or strain. The animal lacks a thymus, is unable to produce T cells and is therefore immunodeficient. Coat Color Hairless, albino background Research Application Tumor biology and xenograft research 0 3 5 7 9 11 13 15 AGE IN WEEKS MALE FEMALE Nude Rats** when ordering, specify RNU STRAIN CODE: 316 (HOMOZYGOUS), 118 (HETEROZYGOUS)§ FEMALE Price Price Up to 28 29–35 36–42 43–49 50–56 57–63 64–70 71 plus 145.70 182.40 219.15 252.95 290.00 323.35 357.85 Price upon request 148.45 182.40 219.15 252.95 290.00 323.35 361.15 Price upon request *Estimated age **Outbred, isolator-maintained § Heterozygous (haired) animals are not immunodeficient. Call 1.800.522.7287 for pricing and availability. Nomenclature Crl:NIH-Foxn1rnu Origin The NIH nude rat was developed in 1979-1980 through a series of matings involving eight inbred rat strains. To Charles River from the National Institute of Health in 2001. This athymic nude rat is T-cell deficient and shows depleted cell populations in thymus-dependent areas of peripheral lymphoid organs. Coat Color White, black, black & white Research Application Tumor biology and xenograft research 600 MEAN WEIGHT +/- 2 STANDARD DEVIATIONS 500 WEIGHT IN GRAMS MALE Age in Days* 400 300 200 100 0 3 5 7 9 11 13 15 AGE IN WEEKS MALE www.criver.com IMMUNODEFICIENT MODELS FEMALE | 43