June 2016 Volume 39, Number 6 In This Issue 849 In This Issue of Diabetes Care Clinical Care/Education/Nutrition/Psychosocial Research 964 Editor9s Note 851 P.C. Dempsey, R.N. Larsen, P. Sethi, J.W. Sacre, N.E. Straznicky, N.D. Cohen, E. Cerin, G.W. Lambert, N. Owen, B.A. Kingwell, and D.W. Dunstan A Special Thanks to the Reviewers of Diabetes Care Profiles in Progress 852 Maria Gordon Buse, MD: A Family Affair Through Six Decades of Diabetes Discovery 973 C.F. Burant, C.R. Buse, K.A. Robinson, and J.B. Buse Metabolic Surgery and the Changing Landscape for Diabetes Care 857 Metabolic Surgery for Type 2 Diabetes: Changing the Landscape of Diabetes Care Metabolic Surgery in the Treatment Algorithm for Type 2 Diabetes: A Joint Statement by International Diabetes Organizations F. Rubino, D.M. Nathan, R.H. Eckel, P.R. Schauer, K.G.M.M. Alberti, P.Z. Zimmet, S. Del Prato, L. Ji, S.M. Sadikot, W.H. Herman, S.A. Amiel, L.M. Kaplan, G. Taroncher-Oldenburg, and D.E. Cummings, on behalf of the Delegates of the 2nd Diabetes Surgery Summit 878 Epidemiology/Health Services Research 982 988 996 1004 902 1010 Clinical Outcomes of Metabolic Surgery: Efficacy of Glycemic Control, Weight Loss, and Remission of Diabetes P.R. Schauer, G. Mingrone, S. Ikramuddin, and B. Wolfe 912 924 1018 Bariatric/Metabolic Surgery to Treat Type 2 Diabetes in Patients With a BMI ,35 kg/m2 Bariatric Surgery: A Potential Treatment for Type 2 Diabetes in Youth Emerging Technologies and Therapeutics 1027 A.S. Shah, D. D’Alessio, M.E. Ford-Adams, A.P. Desai, and T.H. Inge 941 Bariatric Surgery in Obese Patients With Type 1 Diabetes Ethnic Considerations for Metabolic Surgery J.M. Morton 954 Addition of Liraglutide to Insulin in Patients With Type 1 Diabetes: A Randomized Placebo-Controlled Clinical Trial of 12 Weeks N.D. Kuhadiya, S. Dhindsa, H. Ghanim, A. Mehta, A. Makdissi, M. Batra, S. Sandhu, J. Hejna, K. Green, N. Bellini, M. Yang, A. Chaudhuri, and P. Dandona J.P. Kirwan, A. Aminian, S.R. Kashyap, B. Burguera, S.A. Brethauer, and P.R. Schauer 949 Age-Specific Trends From 2000–2011 in All-Cause and Cause-Specific Mortality in Type 1 and Type 2 Diabetes: A Cohort Study of More Than One Million People J.L. Harding, J.E. Shaw, A. Peeters, S. Davidson, and D.J. Magliano D.E. Cummings and R.V. Cohen 934 Differences in Hemoglobin A1c Between Hispanics/Latinos and Non-Hispanic Whites: An Analysis of the Hispanic Community Health Study/Study of Latinos and the 2007–2012 National Health and Nutrition Examination Survey M.L. Avilés-Santa, L.L. Hsu, M. Arredondo, A. Menke, E. Werner, B. Thyagarajan, G. Heiss, Y. Teng, N. Schneiderman, A.L. Giachello, L.C. Gallo, G.A. Talavera, and C.C. Cowie Clinical Outcomes of Metabolic Surgery: Microvascular and Macrovascular Complications T.D. Adams, D.E. Arterburn, D.M. Nathan, and R.H. Eckel Exclusion of Women of Childbearing Potential in Clinical Trials of Type 2 Diabetes Medications: A Review of Protocol-Based Barriers to Enrollment A.L. Phelan, A.R. Kunselman, C.H. Chuang, N.T. Raja-Khan, and R.S. Legro Mechanisms of Diabetes Improvement Following Bariatric/ Metabolic Surgery R.L. Batterham and D.E. Cummings Association Between Use of Lipid-Lowering Therapy and Cardiovascular Diseases and Death in Individuals With Type 1 Diabetes C. Hero, A. Rawshani, A.-M. Svensson, S. Franzén, B. Eliasson, K. Eeg-Olofsson, and S. Gudbj€ ornsdottir J.J. Holst, F. Gribble, M. Horowitz, and C.K. Rayner 893 a-Hydroxybutyric Acid Is a Selective Metabolite Biomarker of Impaired Glucose Tolerance J. Cobb, A. Eckhart, A. Motsinger-Reif, B. Carr, L. Groop, and E. Ferrannini Epidemiology of DiabetesdStatus of a Pandemic and Issues Around Metabolic Surgery Roles of the Gut in Glucose Homeostasis Accelerated Fetal Growth Prior to Diagnosis of Gestational Diabetes Mellitus: A Prospective Cohort Study of Nulliparous Women U. Sovio, H.R. Murphy, and G.C.S. Smith P.Z. Zimmet and K.G.M.M. Alberti 884 Glucose Variability in a 26-Week Randomized Comparison of Mealtime Treatment With Rapid-Acting Insulin Versus GLP-1 Agonist in Participants With Type 2 Diabetes at High Cardiovascular Risk The FLAT-SUGAR Trial Investigators W.T. Cefalu, F. Rubino, and D.E. Cummings 861 Benefits for Type 2 Diabetes of Interrupting Prolonged Sitting With Brief Bouts of Light Walking or Simple Resistance Activities Pathophysiology/Complications Identifying Barriers to Appropriate Use of Metabolic/Bariatric Surgery for Type 2 Diabetes Treatment: Policy Lab Results Prognostic Classification Factors Associated With Development of Multiple Autoantibodies, Dysglycemia, and Type 1 DiabetesdA Recursive Partitioning Analysis J.K. Rubin, S. Hinrichs-Krapels, R. Hesketh, A. Martin, W.H. Herman, and F. Rubino P. Xu and J.P. Krischer, on behalf of the Type 1 Diabetes TrialNet Study Group 1036 Keep up with the latest information for Diabetes Care and other ADA titles via Facebook (/ADAJournals) and Twitter (@ADA_Journals). Icons shown below appear on the first page of an article if more information is available online. All articles in Diabetes Care are available online at diabetes.org/diabetescare. Cover articles ( ) and select content are available free of charge. Other articles are available free to print subscribers or can be purchased as e-prints or reprints. ADA’s Diabetes Core Update podcast is available at diabetesjournals.org and through iTunes. Cardiovascular and Metabolic Risk 1045 e76 Development of Early Adiposity in Infants of Mothers With Gestational Diabetes Mellitus K.M. Logan, R.J. Emsley, S. Jeffries, I. Andrzejewska, M.J. Hyde, C. Gale, K. Chappell, S. Mandalia, S. Santhakumaran, J.R.C. Parkinson, L. Mills, and N. Modi K.D. Boyle, L. Keyes-Elstein, M.R. Ehlers, J. McNamara, M.R. Rigby, S.E. Gitelman, L.J. Weiner, K.L. Much, and K.C. Herold e79 Novel Communications in Diabetes 1052 1056 1060 e81 Long-term Variability in Glycemic Control Is Associated With White Matter Hyperintensities in APOE4 Genotype Carriers With Type 2 Diabetes A. Livny, R. Ravona-Springer, A. Heymann, R. Priess, T. Kushnir, G. Tsarfaty, L. Rabinov, R. Moran, H. Hoffman, I. Cooper, L. Greenbaum, J. Silverman, M. Sano, S.C. Johnson, B.B. Bendlin, and M. Schnaider Beeri e-Letters – Comments and Responses e83 Erratum. A Randomized Controlled Trial of Cognitive Behavioral Therapy for Adherence and Depression (CBT-AD) in Patients With Uncontrolled Type 2 Diabetes. Diabetes Care 2014;37:625–633 e85 Issues and Events Issues and Events e-Letters – Observations e74 Sustained Efficacy of Insulin Pump Therapy in Type 2 Diabetes: 9-Year Follow-up in a Cohort of 161 Patients J. Morera, M. Joubert, R. Morello, A. Rod, B. Lireux, and Y. Reznik Response to Comment on Sj€ oholm et al. Weight Change–Adjusted Effects of Gastric Bypass Surgery on Glucose Metabolism: 2- and 10-Year Results From the Swedish Obese Subjects (SOS) Study. Diabetes Care 2016;39:625–631 K. Sj€ oholm, L.M.S. Carlsson, and M. Peltonen e86 S.A. Safren, J.S. Gonzalez, D.J. Wexler, C. Psaros, L.M. Delahanty, A.J. Blashill, A.I. Margolina, and E. Cagliero 1066 Comment on Sj€ oholm et al. Weight Change–Adjusted Effects of Gastric Bypass Surgery on Glucose Metabolism: 2- and 10-Year Results From the Swedish Obese Subjects (SOS) Study. Diabetes Care 2016;39: 625–631 K. Spaniolas and W.J. Pories Erratum 1065 Continuous Glucose Monitoring in Patients With Type 1 Diabetes Using Insulin Injections N.C. Foster, K.M. Miller, W.V. Tamborlane, R.M. Bergenstal, and R.W. Beck, for the T1D Exchange Clinic Network HLA-A*24 Carrier Status and Autoantibody Surges Posttransplantation Associate With Poor Functional Outcome in Recipients of an Islet Allograft S. Demeester, E.M. Balke, B.J. Van der Auwera, P. Gillard, R. Hilbrands, D. Lee, U. Van de Velde, Z. Ling, B.O. Roep, D.G. Pipeleers, F.K. Gorus, and B. Keymeulen Omentin-1, Adiponectin, and the Risk of Developing Type 2 Diabetes C. Wittenbecher, J. Menzel, M. Carstensen-Kirberg, R. Biemann, R. di Giuseppe, A. Fritsche, B. Isermann, C. Herder, K. Aleksandrova, H. Boeing, C. Weikert, and M.B. Schulze Heterogeneous Contribution of Insulin Sensitivity and Secretion Defects to Gestational Diabetes Mellitus C.E. Powe, C. Allard, M.-C. Battista, M. Doyon, L. Bouchard, J.L. Ecker, P. Perron, J.C. Florez, R. Thadhani, and M.-F. Hivert Two- and Four-Hour Tests Differ in Capture of C-Peptide Responses to a Mixed Meal in Type 1 Diabetes Comment on American Diabetes Association. Approaches to Glycemic Treatment. Sec. 7. In Standards of Medical Care in Diabetesd2016. Diabetes Care 2016;39(Suppl. 1): S52–S59 D. Giugliano, M.I. Maiorino, G. Bellastella, and K. Esposito e88 Response to Comment on American Diabetes Association. Approaches to Glycemic Treatment. Sec. 7. In Standards of Medical Care in Diabetesd2016. Diabetes Care 2016; 39(Suppl. 1):S52–S59 W.H. Herman, R.R. Kalyani, D.J. Wexler, D.R. Matthews, and S.E. Inzucchi Cover: Surgery in Military Hospital During the First World War, England, 20th Century. By De Agostini/G. Nimatallah. For more information, please visit gettyimages.com. This issue of Diabetes Care includes a special article collection “Metabolic Surgery and the Changing Landscape for Diabetes Care” (pp. 857–963).