Crafting a Message for Publication Graham McMahon MD MMSc Editor for Medical Education, NEJM Specific Goals To familiarize you with the “publishing biz” and how it works To help you think about how to convert your scholarship into publishable papers • Research • Innovative curricula • New teaching/learning methods • Other projects Help you strategize your work with editors Overall Objective To help you become a • Better • Smarter • More successful writer for publication as an educator From the Author’s Perspective “It’s publish or perish, and he hasn’t published.” 11 Why Experiment? Evidence based education! Rigor in educational approaches Improved quality for learners Personal and professional value Elevate the field 6 Challenges in Educational Research Participants are actively learning over time • Interventions must demonstrate additional increments of performance improvement Comparison groups difficult to identify • Placebo groups challenging in education Small sample sizes and short studies Open-label • Students may be vulnerable to experimental coercion and to change behavior as a result of being in an experiment • Contamination between research groups is common Time between learning and behavior can be long • Dependence on intermediary endpoints Frequent changes in regulatory expectations Learners increasingly have survey fatigue 7 Challenges for Educational Researchers Conflicting demands Isolation Lack of programmatic support Constrained budget Activities not valued Why Write? To share your ideas, programs, research To get feedback from others To incrementally advance the knowledge base To get appropriate recognition Top Issues in MedEd Research Todres M, Rogers R. BMJ. 2007 Aug 18;335(7615):333-5 10 Write about what you believe in Ability to convince others Get it done Withstand the • slings and arrows of publishing and • its highly variable, unpredictable and intermittent reinforcement How are papers organized? Logical structure with a basic formula Five sections • Abstract: summary • Introduction: set the stage, why important, state hypothesis • Methods: what you did, IRB • Results: data only • Discussion: what you found, what it means, what’s next, what you found Introduction Start building the case why the reader should be interested in your study Describe the area being studied Review the pertinent literature in that area that leads ups to your study Conclude with a description of how your study is the logical next step, fills a gap, or in other ways adds to the existing literature Write hypothesis Methods Describe what you did, so the reader can understand and someone else potentially could repeat your study • Setting • Sample • Timeframe • Outcomes • Measures • Data analysis plan Results Describe what you found (not what you believe it means) Present the positive and negative data of your findings in • Text – little space, most important findings • Tables and figures – present more of the data Discussion Summarize what you found Describe what you believe the findings displayed in your Results section mean in the context of other research Describe the strengths and limitations of your study and findings, without overgeneralizing To conclude, describe where your findings lead and possible logical next steps Aim High Who is your audience? What do they ready? Review what the Journal is currently publishing Consult with colleagues • Time to first decision • Review process • Duration Look at Journal’s impact factors PRIMARY MED ED JOURNALS Education Papers don’t only get published in education journals Med Educ 2.7 Acad Med 2.3 Adv Health Sci Educ Theory Pract 1.4 Med Teach 1.3 J Contin Educ Health Prof 1.0 Teach Learn Med 0.7 Acad Psychiatry BMC Med Educ 1.2 J Surg Educ Clin Teach Write About Education and the Other Things You Do/Study PRIMARY MEDICAL JOURNALS N Engl J Med 47.0 JAMA 28.9 Lancet 30.8 Ann Intern Med 16.2 BMJ ( 13.7 CMAJ 7.2 J Gen Intern Med 2.6 Am J Surg 2.3 J Fam Pract 1.4 Fam Med 1.3 Mission of a Journal Find the best work Report it dispassionately How does the process work? Manuscripts Received 7,000 6,000 5,000 4,000 3,000 2,000 1,000 0 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 Types of Research 2012 Case Reports Other Genetics Biology Epidemiology Small Interventions Large Interventions Origin of Research 100.0% 90.0% 80.0% 70.0% 60.0% US 50.0% US(%) 40.0% 30.0% 20.0% 10.0% 0.0% International NonUS(%) Initial Submission Editor-in-chief Associate/ Deputy Editor Peer Review Editorial Meeting Statistical Review Initial Decision Initial Submission Editor-in-chief Associate/ Deputy Editor Peer Review Editorial Meeting Statistical Review Initial Decision Initial Submission Editor-in-chief Associate/ Deputy Editor Peer Review Editorial Meeting Statistical Review Initial Decision Peer Review Peer review is a mechanism by which the research community asserts quality control. It has become an essential feature of the decision-making processes used by most funding agencies and all major medical journals. A feature common to all peer reviews is that they are performed by one or more individuals active in a field of study that is central to the item being reviewed. Types of Peer Review Double blind • Article is de-identified, and identity of reviewer remains confidential. Single blind • Reviewer knows identity of authors. Authors don’t find out identity of reviewers. Open • Identity of authors, reviewers known to all • Often reviews are published with the article. Editors use the Reviews Once reviews are in the editor reads the paper and the reviews The editor, not the reviewer, makes the decision about the paper Reviewers’ comments are valuable, but reviewers are only consultants to the thinking process Reviewers’ Grades of Papers Rejected Accepted Editors are looking for work that is…. Important Informative Novel Ethical Important informative novel ethical What is Important? Research results that will • change or affect practice, • teach us about biology, or • serve as a launching platform to define new directions in medicine Important informative novel ethical What is Informative? Study adds appreciably to available data Conclusions provide clear direction Conclusions follow from the data • Free from commercial or intellectual bias Important informative novel ethical What is Novel ? A study that • breaks new ground, • defines new treatments or • resolves major controversies Important informative novel ethical What is Ethical? Adequate informed consent obtained Minimum number of subjects put at risk to gain needed information Honest reporting Important informative novel ethical Associate Editor makes a decision Full consideration? • Manuscript is presented to all the editors Minimal consideration? • Manuscript is on the agenda but discussion is minimal Initial Submission Editor-in-chief Associate/ Deputy Editor Peer Review Editorial Meeting Statistical Review Initial Decision The Editors Meet Initial Submission Editor-in-chief Associate/ Deputy Editor Peer Review Editorial Meeting Statistical Review Initial Decision About 20% of papers fail at this step Possible Decisions Initial Reject 60.5% Reject After Peer Review 33.8% Needs additional Experiments-1% We’re very interested 0.8% We’re interested 3.5% Three Major Reasons for Rejection Quality – the science is flawed Novelty – the science is good, but has previously been published or does not advance the field Specialty – it’s good, but not of general interest and belongs in a specialty journal Reasons for Rejection Bordages G. Acad. Med. 2001;76:889–896. Initial Submission Revision Submitted Editor-in-chief Associate/ Deputy Editor Peer Review Editorial Meeting Statistical Review Initial Decision Associate Editor Peer Review Editorial Meeting Final Decision Expanded Mission of Medical Journals Find the best work Solicit submissions Meet authors needs for expeditious review Best reviewers Thoughtful debate Report it dispassionately Careful manuscript editing Content Language Remove ‘spin’ Clear graphics Supplementary commentary Disseminate the findings Attract readers to the site Email and print Support teachers Support the reader Easy search and retrieval Portfolio Provide an educational program Support the scientific mission Meet the needs of readers Enhance the experience Differing Perspectives Authors role • • • • • Journal’s Role Do the right study • evaluate work do determine if it is important, informative, Write about it clearly Report it dispassionately novel and ethical • ensure the data has been Submit to the right Journal analyzed appropriately and Respond clearly that conclusions follow from the data • relationships that could lead to perceptions of bias are disclosed Submissions in 2012 (n=14,441) Perspectives NEJM.org Audience PCPs = FMs + IMs + GP 46% Assigning the Manuscripts About 10% of papers are rejected at this stage Assigned manuscripts are sent to the Associate Editors Associate Editors Local experts in major areas of medicine Being local facilitates in-person meetings 10 AEs: • • • • • Cardiology, Infectious Disease, Cancer, Endocrinology, Gastroenterology, •Maternal-Fetal •Neurology •Office Practice, •Health Policy & •Vascular Disease Honest Reporting All the data, analyzed as intended • Vioxx (VICTOR) • Rosiglitazone (RECORD) Full disclosure • Henschke et al • Others Articles Published 2011 Original Research n=225 4.9% Review Articles n=70 25.0% Letters n=700 20% Images n=104 2.2% Editorials n=99 95% Perspectives n=216 25% Other Articles n=91 18% Research Published in NEJM NEJM 100% 90% 80% Percentage Other 70% Brief Reports 60% Biology/Genetics 50% Epidemiology 40% Small Interventions 30% 20% 10% 64 62 69 77 84 85 0% Year 99 92 91 115 88 Large Interventions Percentage Percentage of the Top 100 citations/decade in the NEJM Year