STD Surveillance 2001 Adapted from CDC by Jill Gallin, CPNP Assistant Professor of Clinical Nursing The number of disease reported does not equal the incidence Factors affecting report data • Reporting systems – Laboratories – Providers – Information systems • Increase or decrease in screening • Sensitivity of diagnostic tests/ Ability to diagnose disease Chlamydia Sexually Transmitted Disease Surveillance 2001 Division of STD Prevention Chlamydia — Number of states that require reporting of Chlamydia trachomatis infections: United States, 1987–2001 No. of states 50 40 30 20 10 0 1987 88 89 90 91 92 93 94 95 96 97 98 99 2000 01 Chlamydia — Reported rates: United States, 1984–2001 Rate (per 100,000 population) 300 240 180 120 60 0 1984 86 88 90 92 94 96 98 2000 Chlamydia — Rates by state: United States and outlying areas, 2001 231.3 212.7 104.9 165.4 217.9 169.2 156.3 303.6 241.2 169.9 244.5 194.7 231.0 187.3 241.8 307.8 279.6 331.7 352.0 250.9 134.5 301.0 343.8 225.0 303.7 129.7 259.1 249.3 219.7 274.6 273.5 272.3 382.1 Guam 278.4 414.6 326.6 413.4 334.5 399.2 437.7 VT NH MA RI CT NJ DE MD 312.8 235.4 Rate per 100,000 population (n= 7) <=150 150.1-300 (n= 29) (n= 17) >300 332.7 Puerto Rico 72.2 104.8 111.9 163.8 277.8 226.6 193.9 356.4 295.3 Virgin Is. 120.6 Note: The total rate of chlamydia for the United States and outlying areas (including Guam, Puerto Rico and Virgin Islands) was 275.5 per 100,000 population. Chlamydia — Rates by region: United States, 1984–2001 Rate (per 100,000 population) 350 280 210 140 West Midwest Northeast South 70 0 1984 86 88 90 92 94 96 98 2000 Chlamydia — Rates by sex: United States, 1984–2001 Rate (per 100,000 population) 450 360 270 Men Women 180 90 0 1984 86 88 90 92 94 96 98 2000 Chlamydia — Age- and sex-specific rates: United States, 2001 Men 3,000 Rate (per 100,000 population) 2,400 1,800 1,200 600 0 9.9 375.9 604.9 284.7 140.4 70.3 37.1 15.9 5.5 2.2 114.2 Age 10-14 15-19 20-24 25-29 30-34 35-39 40-44 45-54 55-64 65+ Total Women 0 600 1,200 1,800 2,400 3,000 139.8 2,536.1 2,447.0 824.6 301.9 119.1 51.4 18.1 5.1 2.9 436.3 Chlamydia — Trends in positivity among 15-44 year old women tested in family planning clinics by HHS regions, 1988–2001 Region VIII Region V Region II 7.5 7.2 7.1 6.0 Region X 13.0 5.6 6.0 5.0 4.6 4.6 5.3 5.4 94 95 96 97 98 99 00 01 5.6 6.6 6.4 5.7 6.2 6.2 Region I 7.3 6.7 4.9 4.6 4.9 5.1 4.1 96 97 98 99 00 01 97 98 99 00 01 97 98 99 00 01 10.0 9.5 8.0 6.7 5.0 4.7 4.9 5.3 5.3 4.1 3.9 3.9 4.6 X 88 89 90 91 92 93 94 95 96 97 98 99 00 01 II VIII V Region IX 5.1 5.2 VII IX I Region III 7.4 III 6.0 5.3 5.6 6.0 6.3 6.0 5.5 94 95 96 97 98 99 00 01 VI 5.9 6.3 6.2 6.3 IV 96 97 98 99 00 01 Region IV 8.9 10.1 9.5 8.6 8.5 Region VI Region VII 9.7 8.7 8.8 8.5 8.4 8.9 97 98 99 00 01 4.9 4.7 5.4 5.3 5.5 5.4 96 97 98 99 00 01 96 97 98 99 00 01 Note: Trends adjusted for changes in laboratory test method and associated increases in test sensitivity. No data on laboratory test method available for Region VII in 1995 and Regions IV and V in 1996. SOURCE: Regional Infertility Prevention Program; Office of Population Affairs; Local and State STD Control Programs; Centers for Disease Control and Prevention Gonorrhea Sexually Transmitted Disease Surveillance 2001 Division of STD Prevention Gonorrhea — Reported rates: United States, 1970–2001 and the Healthy People year 2010 objective Rate (per 100,000 population) 500 Gonorrhea 2010 Objective 400 300 200 100 0 1970 73 76 79 82 85 88 91 94 97 Note: The Healthy People 2010 (HP2010) objective for gonorrhea is 19.0 cases per 100,000 population. 2000 Gonorrhea — Rates by region: United States, 1981–2001 and the Healthy People year 2010 objective Rate (per 100,000 population) 600 West Midwest Northeast South 2010 Objective 480 360 240 120 0 1981 83 85 87 89 91 93 95 97 99 2001 Gonorrhea — Rates by sex: United States, 1981–2001 and the Healthy People year 2010 objective Rate (per 100,000 population) 600 Male Female 2010 Objective 480 360 240 120 0 1981 83 85 87 89 91 93 95 97 99 2001 Gonorrhea — Rates by race and ethnicity: United States, 1981–2001 and the Healthy People year 2010 objective Rate (per 100,000 population) 2,500 2,000 White Black Hispanic Asian/Pac Isl Am Ind/AK Nat 2010 Objective 1,500 1,000 500 0 1981 83 85 87 89 91 93 95 97 99 2001 Gonorrhea — Age- and sex-specific rates: United States, 2001 Men 750 Rate (per 100,000 population) 600 450 300 150 0 8.2 307.5 563.6 328.4 203.9 134.3 90.5 46.8 17.2 4.5 128.6 Age 10-14 15-19 20-24 25-29 30-34 35-39 40-44 45-54 55-64 65+ Total 0 Women 150 300 450 600 750 51.8 703.2 664.1 249.4 112.7 57.8 31.2 9.4 2.0 0.9 128.5 Gonococcal Isolate Surveillance Project (GISP) — Location of participating clinics and regional laboratories: United States, 2001 Tripler AMC Gonococcal Isolate Surveillance Project (GISP) — Penicillin and tetracycline resistance among GISP isolates, 2001 79.1% 1.5% 5.2% 0.5% 2.9% Susceptible PPNG 4.4% TRNG 6.4% PenR PPNG/TRNG TetR CMRNG Note: PPNG=penicillinase-producing N. gonorrhoeae; TRNG=plasmid-mediated tetracycline resistant N. gonorrhoeae; PPNG-TRNG=plasmid-mediated penicillin and tetracycline resistant N. gonorrhoeae; PenR=chromosomally mediated penicillin resistant N. gonorrhoeae; TetR=chromosomally mediated tetracycline resistant N. gonorrhoeae; CMRNG=chromosomally mediated penicillin and tetracycline resistant N. gonorrhoeae. Gonococcal Isolate Surveillance Project (GISP) — Percent of Neisseria gonorrhoeae isolates with resistance or intermediate resistance to ciprofloxacin, 1990–2001 Percent 3.0 2.4 Resistance Intermediate resistance 1.8 1.2 0.6 0.0 1990 91 92 93 94 95 96 97 98 99 Note: Resistant isolates have ciprofloxacin MICs >1 mg/mL. Isolates with intermediate resistance have ciprofloxacin MICs of 0.125 - 0.5 mg/mL. Susceptibility to ciprofloxacin was first measured in GISP in 1990. 2000 01 Syphilis Sexually Transmitted Disease Surveillance 2001 Division of STD Prevention Syphilis — Reported cases by stage of illness: United States, 1941–2001 Thousands of cases 600 P&S Early Latent Total Syphilis 480 360 240 120 0 1941 46 51 56 61 66 71 76 81 86 91 96 2001 Primary and secondary syphilis — Reported rates: United States, 1970–2001 and the Healthy People year 2010 objective Rate (per 100,000 population) 25 P&S Syphilis 2010 Objective 20 15 10 5 0 1970 73 76 79 82 85 88 91 94 97 Note: The Healthy People 2010 (HP2010) objective for primary and secondary syphilis is 0.2 case per 100,000 population. 2000 Primary and secondary syphilis — Rates by state: United States and outlying areas, 2001 1.0 0.0 0.1 0.0 0.4 0.7 0.1 0.4 0.1 0.2 1.6 0.2 0.8 0.6 0.4 0.5 3.3 1.6 0.5 3.5 0.9 1.7 1.0 2.5 0.7 0.3 0.5 1.4 1.2 5.5 5.8 1.8 5.9 Guam 7.8 4.9 3.2 5.1 2.3 3.9 0.0 VT NH MA RI CT NJ DE MD 4.3 3.0 Rate per 100,000 population <=.2 .21-4 >4 1.0 Puerto Rico 6.4 0.5 0.1 0.7 0.9 0.4 1.6 1.8 5.0 Virgin Is. 0.0 Note: The total rate of primary and secondary syphilis for the United States and outlying areas (including Guam, Puerto Rico and Virgin Islands) was 2.2 per 100,000 population. The Healthy People year 2010 objective is 0.2 per 100,000 population. (n= 10) (n= 34) (n= 9) Primary and secondary syphilis — Rates by region: United States, 1981–2001 and the Healthy People year 2010 objective Rate (per 100,000 population) 50 West Midwest Northeast South 2010 Objective 40 30 20 10 0 1981 83 85 87 89 91 93 95 97 99 2001 Primary and secondary syphilis — Rates by sex: United States, 1981–2001 and the Healthy People year 2010 objective Rate (per 100,000 population) 25 Male Female 2010 Objective 20 15 10 5 0 1981 83 85 87 89 91 93 95 97 99 2001 Primary and secondary syphilis — Rates by race and ethnicity: United States, 1981–2001 and the Healthy People year 2010 objective Rate (per 100,000 population) 150 White Black Hispanic Asian/Pac Isl Am Ind/AK Nat 2010 Objective 120 90 60 30 0 1981 83 85 87 89 91 93 95 97 99 2001 Primary and secondary syphilis — Male to female rate ratios: United States, 1981–2001 Male-Female rate ratio 5:1 4:1 3:1 2:1 1:1 0 1981 83 85 87 89 91 93 95 97 99 2001 Primary and secondary syphilis — Age- and sex-specific rates: United States, 2001 Men Rate (per 100,000 population) 7.5 6.0 4.5 3.0 1.5 0.0 0.0 1.4 5.0 5.9 6.4 7.2 5.3 3.4 1.4 0.4 3.0 Age 10-14 15-19 20-24 25-29 30-34 35-39 40-44 45-54 55-64 65+ Total 0.0 Women 1.5 3.0 4.5 0.2 2.5 3.8 3.1 3.0 2.9 2.0 0.9 0.2 0.0 1.4 6.0 7.5 Congenital syphilis — Rates for infants <1 year of age: United States, 1981–2001 and the Healthy People year 2010 objective Rate (per 100,000 live births) 125 Cong. Syphilis 2010 Objective 100 75 50 25 0 1981 83 85 87 89 91 93 95 97 Note: The Healthy People 2010 (HP2010) objective for primary and secondary syphilis is 0.2 case per 100,000 population. The surveillance case definition for congenital syphilis changed in 1988. 99 2001 Other Sexually Transmitted Diseases Sexually Transmitted Disease Surveillance 2001 Division of STD Prevention Chancroid — Reported cases: United States, 1981–2001 Cases (in thousands) 5 4 3 2 1 0 1981 83 85 87 89 91 93 95 97 99 2001 Genital herpes — Initial visits to physicians’ offices: United States, 1966–2001 Visits (in thousands) 250 200 150 100 50 0 1966 69 72 75 78 81 84 87 SOURCE: National Disease and Therapeutic Index (IMS America, Ltd.) 90 93 96 99 Genital herpes simplex virus type 2 infections — Percent seroprevalence according to age in NHANES* II (1976-1980) and NHANES III (1988-1994) Percent 40 32 24 16 NHANES II NHANES III 8 0 12-19 20-29 30-39 40-49 Age Group Note: Bars indicate 95% confidence intervals. *National Health and Nutrition Examination Survey 50-59 60-69 70+ Genital warts — Initial visits to physicians’ offices: United States, 1966–2001 Visits (in thousands) 400 320 240 160 80 0 1966 69 72 75 78 81 84 87 SOURCE: National Disease and Therapeutic Index (IMS America, Ltd.) 90 93 96 99 Nonspecific urethritis — Initial visits to physicians’ offices by men: United States, 1966–2001 Visits (in thousands) 400 320 240 160 80 0 1966 69 72 75 78 81 84 87 SOURCE: National Disease and Therapeutic Index (IMS America, Ltd.) 90 93 96 99 Trichomonal and other vaginal infections — Initial visits to physicians’ offices: United States, 1966–2001 Visits (in thousands) 4,500 Trichomonal Other Vaginitis 3,600 2,700 1,800 900 0 1966 69 72 75 78 81 84 87 SOURCE: National Disease and Therapeutic Index (IMS America, Ltd.) 90 93 96 99