SWINE HEALTH Dr. Randy Harp Herd Health Problems ► Biosecurity External biosecurity Internal biosecurity Development of a Biosecurity Plan ► Attitude “State of Mind” Unforgiving attitude required because disease is unforgiving Development of a Biosecurity Plan cont. ► Establish Herd Health Goals Healthy, productive system that can be maintained Type of production system Facility location Health status of start-up herd Cost Development of a Biosecurity Plan cont. ► External Biosecurity Keeping out new diseases ►Isolation/acclimatization (incoming stock) Separate facility > 200 yards from herd 45 – 60 days First 30 days (isolation) Animals observed and blood tested PRRS, PRV, brucellosis, TGE Parvo, Swine Influenza Last 30 days (acclimatization) Vaccinate for Lepto, Erysiplas, Parvo Development of a Biosecurity Plan cont. ► External Biosecurity Keeping out new diseases ►Isolation/acclimatization (incoming stock) cont. Animals exposed to cull sows Allow opportunity to build immunity Donor herd health should be compared closely to that of the recipient herd Administer vaccine as indicated by recipient herd Limit use of antibiotics Development of a Biosecurity Plan cont. ► External Biosecurity Keeping out new diseases ►Semen Know isolation/acclimatization of boar stud Adequate disease monitoring program for boar stud Procedures for boar stud should be as strict as those for production units Development of a Biosecurity Plan cont. ► External Biosecurity Restrict access to visitors & create barriers ►Perimeter fence ►Padlock all outside doors ►Use signs ►Require “clean out” time for visitors ►Shower in / shower out ►Provide clothing and boots ►Sanitize all incoming equipment ►Feed trucks limited Development of a Biosecurity Plan cont. ► External Biosecurity Develop and enforce strict chute rules ►Trucks with manure should be excused ►Load outs designed to prevent entry ►Establish sacred zones (off limit to trucks) ►Guillotine gate ►Boots should be provided for drivers ►Clean, disinfect, and dry the landout Development of a Biosecurity Plan cont. ► External Biosecurity Keep out other species of animals and insects ►Rodents, birds, dogs, cats, flies ►All can transmit diseases ►Rats and flies can travel two miles Development of a Biosecurity Plan cont. ► External Biosecurity Locate new production units away from other pigs ► Distance between swine production units ► Pig density ► Probability of other pigs coming to area Pathogen Minimum distance to prevent transmission Mycoplasma pneumonia 2 miles TGE .5 miles Atrophic rhinitis .5 miles Strep suis 2 miles Pseudorabies 5 miles PRRS ??? Development of a Biosecurity Plan cont. ► Internal Biosecurity Adopt optimum production system design ►All-in / all-out ►Multiple-site production ►SEW (segregated early weaning) Development of a Biosecurity Plan cont. ► Internal Biosecurity Install barriers ►Perimeter ►Bird fence wire ►Tree line ►Dead animal disposal Development of a Biosecurity Plan cont. ► Internal Biosecurity Sanitization ►Decontaminate rooms between groups ►Use high pressure spray, rinse all surfaces, disinfect, dry, leave vacant Development of a Biosecurity Plan cont. ► Vaccination Program Leptospirosis, parvovirus, erysiplas 2x/year TGE, PRRS, Atrophic rhinitis, strep suis & ?? Design with veterinarian Development of a Biosecurity Plan cont. ► Internal and External Parasite Control All incoming breeding stock should be treated Use fecal and skin monitoring Development of a Biosecurity Plan cont. ► Slaughter Checks Quarterly checks ►Liver and lung lesions ►Nasal turbinates Only portion of herd need to be tested ►> 140 animals need 11 animals ►> 1,000 animals need 29 animals Development of a Biosecurity Plan cont. ► Monitoring Quarterly sampling for PRV and brucellosis for seedstock herds Serological testing for other diseased known to be in area Feed testing for mycotoxins Development of a Biosecurity Plan cont. ► Feed additives Growth promotant antibiotics Alternative Disease Control Procedures Alternative Disease Control Procedures ► Closed herd Specific pathogen free (SPF) Non SPF ► Isolation of incoming breeding stock Alternative Disease Control Procedures ► Systems management Multiple site production system All-in / all-out Segregated early weaning (SEW) ► No control Specific Pathogen Free (SPF) Specific Pathogen Free (SPF) ► SPF is an attempt to Control diseases Improve management Specific Pathogen Free (SPF) ► Initially set up to control Atrophic rhinitis Mycoplasma hyoneumonia Specific Pathogen Free (SPF) cont. ► Now designed to eliminate & prevent certain chronic growth retarding diseases Mange Lice Swine dysentery Atrophic rhinitis Mycoplasma pneumonia Pseudorabies Brucellosis SPF scheme ► Sow – 112 to 114 days (C-section) ► Take pigs from sow, put in sterile environment ► Rear in isolation ► Restock other farms SPF pigs no immunological control, introduce to other pigs SPF classification ► Primary SPF pigs from C-section ► Secondary SPF Pigs from primary SPF or Pigs from other SPF farms Accreditation Requirements ► Proof of origin ► Brucellosis validation ► Pseudorabies validation ► Herd inspection from veterinarian Free of: ►lice / mange ►Swine dysentery Accreditation Requirements cont. ► Quarterly health and disease reports ► Submit quarterly litter registration ► Quarterly slaughter checks (10 head) Atrophic rhinitis Mycoplasma hyopneumonia Scour Diseases TGE (Transmissible gastroenteritis) ► Cause - corona virus ► Symptoms pigs - major cause of death in young Baby pigs ►Sudden vomiting ►Watery, yellowish diarrhea ►Odor ►90% death loss < 14 days old TGE (Transmissible gastroenteritis) cont. ► Symptoms cont. Older pigs ► Appetite loss ► Diarrhea (mild) ► Control / Prevention Vaccine Good sanitation Bird and rodent control Management E. Coli (colibacillosis) ► Cause – bacteria ► Symptoms Pale, yellow, watery diarrhea Dehydration Edema- produced by toxin of E. Coli Swollen eyelids, stomach Nervous signs ► Staggering, head tilting, paddling, stumbling, dog sitting E. Coli cont. ► Control / Prevention Sanitation Management vaccination Swine Dysentery ► Cause – bacteria (sepulina hyodysenteriae) ► Symptoms Stool contains blood and mucus Dehydration Poor gain and efficiency Some cases, death Swine Dysentery cont. ► Control / Prevention Management Sanitation Antibiotics Vaccine Control mice which harbor bacteria for 1 year Rotavirus ► Cause – virus ► Symptoms – nursing pigs (about 3 weeks old) White, pasty scours Generally do not lose much weight ► Control / Prevention Management Sanitation Vaccine (antibiotics not effective) Coccidiosis ► Cause – protozoa shed in feces ► Symptoms – nursing pigs (7 - 10 days old) Diarrhea – yellow, light green / gray Dehydration ► Control / Prevention Manure removal (it is shed in feces) Management (wash sows before entering farrowing house) sanitation Salmonella ► Cause – bacteria ► Symptoms Acute septicemia (generalized infection of blood and organs) Diarrhea Anorexia Fever, cough Ears, nose, tail, feet,& abdomen become light purple Nervous disorders ► Posterior weakness, paddling, restlessness Salmonella cont. ► Control / Prevention Antibacterials for treatment Removal of affected pigs Management Sanitation Vaccine Carrier pigs are indistinguishable from other pigs Reproductive Diseases Brucellosis ► Cause – brucella suis, bacteria ► Clinical Signs Fever – 5-7 days Abortion – any time during gestation Weak pigs at birth Genital tract infections & sterility Brucellosis cont. ► Diagnosis Blood agglutination test ► Prevention Herd testing ►Initial test ►Retain validation Retest all breeding stock annually Test 20% of sows annually – cull sows Brucellosis cont. ► Prevention cont. Introduce only negative animals into herd Vaccination is unsuccessful Under SPF, must be brucellosis free Leptospirosis ► Cause Numerous organisms – bacteria Transferable across species ► Symptoms Fever, diarrhea Abortions – late gestation Immature pigs Leptospirosis cont. ► Prevention Vaccination once every 6 months is effective Use 5 way vaccine at weaning Blood test in not effective SPF requires vaccination Parvovirus Cause – virus Symptoms ►Embryonic & fetal deaths ►Mummified feti ►Small litters ►Infrequent abortion ►Delayed return to estrus ►Anestrus Parvovirus cont. ► Prevention / Control Vaccination Pseudorabies (Aujesky’s disease) ► Cause – herpes virus ► Symptoms Young pigs ►90% death loss in 3 -4 week olds ►40% death loss in 12 week olds Older pigs > 50 lbs. ►Low death rates ►Respiratory distress Pseudorabies (Aujesky’s disease) cont. ► Symptoms cont. Sows ► Abortion – early gestation ► Retention of fetus – late gestation ► Death of entire litter in 1 – 2 days General signs ► Fever ► Convulsions & trembling ► Ear infection ► Off feed ► Diarrhea Pseudorabies (Aujesky’s disease) cont. ► Diagnosis Blood test ► Vaccination Modified live virus Produces positive blood test Pseudorabies (Aujesky’s disease) cont. ► Control rules Must have permit before entry Must have passed blood test in last 30 days or be from PRV free herd ► Eradication Effort underway to eradicate PRV from the US Porcine Reproductive & Respiratory Syndrome (PRRS) ► Cause – virus ► Prevalence – 80 – 90% of swine in OK test positive (LUCE) ► Transmission – animal to animal Porcine Reproductive & Respiratory Syndrome (PRRS) cont. ► Clinical signs Breeding females Fever – increased stillborns Depression – weak, liveborn pigs Abortions – preweaning mortality Porcine Reproductive & Respiratory Syndrome (PRRS) cont. Nursery pigs ►Rapid, labored breathing ►Poor performance Finishing pigs ►Fever ►Depression ►Off feed Porcine Reproductive & Respiratory Syndrome (PRRS) cont. ► Control Vaccination Depopulation / repopulation Multiple site production Erysipelas ► Cause – bacteria ► Symptoms Fever Abortion Diamond shaped lesions on skin ► Control / Prevention Penicillin Vaccination Streptococcus Suis ► Cause – bacteria ► Symptoms Weaned pigs ► Meningitis ► Anorexia ► Reddening of skin ► Nervous disorders – loss of balance, paddling, shaking, convulsions ► Blindness & deafness ► If serious, can lead to “greasy pig” Streptococcus Suis cont. ► Symptoms cont. Breeding herd ► Decreased conception rates ► Decreased farrowing rate ► Vaginal discharge Pneumonia ► Treatment / Control Penicillin Management – reduce stress, ventilation, humidity Vaccine Respiratory Diseases Mycoplasma Hyopneumonia ► Cause – mycoplasma hyopneumonia bacteria Infectious respiratory disease of swine ► Prevalence – 80 – 90% of US swine herds ► Transmission – animal to animal contact Mycoplasma Hyopneumonia cont. ► Clinical signs Sneezing Dry cough Listlessness Poor growth performance ► Economic Losses Death loss Reduced feed efficiency 10 – 30% gain Mycoplasma Hyopneumonia cont. ► Treatment ► Control – antibiotics – Lincomycin – depopulation Can live with it with good management, i.e. no stress, good nutrition Actinobacillus Pleuropneumonia ► Cause – bacteria ► Transmission – pig to pig contact ► Clinical signs Sudden death 20 – 40% High fever Loss of appetite (anorexia) Lesions on lungs of growing swine Actinobacillus Pleuropneumonia cont. ► Control Vaccine Good herd health Antibiotics Management (all-in / all-out, age segregation) Atrophic Rhinitis ► Cause Bordetella bacteria Pasturella bacteria ► Transmission Pig to pig contact Atrophic Rhinitis cont. ► Clinical signs ►Affects nasal turbinate bone development ►Early sign in baby pigs ►Sneezing ►Distortion of nose ►Pneumonia ►Black areas around eyes Atrophic Rhinitis cont. ► Control ►Vaccination ►Depopulation ►antibiotics – only way to completely get rid of Porcine Respiratory Disease Complex (PRDC) ► Cause – both viral & bacterial pathogens Primary bacterial pathogens ► Mycoplasma hyopneumonia ► Actinobacillus pleuropneumonia Secondary bacterial pathogens ► Pasturella multocida ► Strep suis ► Salmonella Usually a combination of PRRS, swine flu, PRV, & PRCV Porcine Respiratory Disease Complex (PRDC) cont. ► Symptoms Acute depression Anorexia Fever Nasal discharge Coughing, labored breathing Increased mortality Reduced F/G Increased days to market Porcine Respiratory Disease Complex (PRDC) cont. ► Prevention / Control Management (AI – AO, SEW, multi-site) Strict biosecurity Vaccination for 1° and 2° pathogens Anthelmintics ► Ivomec ► Dectomax ► Atguard ► Pyrantel Tartrate ► Fenbendazole (Safeguard/Panacur) ► Piperazine ► Levisole ► Banmith