Morrell, P.L., E.S. Buckler, and J. Ross-Ibarra. 2012. Crop genomics: advances and applications. Nature Reviews Genetics 13: 85-96. Study Questions 1) What features of plant genomes create challenges for comparative genomic analyses that are not typically as problematic for studies of mammalian genomes? 2) Discuss one or more ways that earlier theories about crop domestication have been revised based on recent molecular evidence. 3) How can identification of loci that have been targets of selection for adaptation to cropping systems be useful for future breeding efforts? 4) Do you foresee that targeted genome editing technologies will play an important role in plant breeding programs in the near future?