The Cell Membrane AKA The Plasma Membrane AKA The Lipid Bilayer Some Electron Micrographs Made up of two layers of phospholipids and proteins with some cholesterol • Basic Lipid Bilayer Structure • Individual molecules not bonded to one another – held together by hydrophilic and hydrophobic ends of lipids •Allows membrane to “flow” – form vacuoles, divide, etc. •Kinda like soap bubbles Carbohydrate chains on the outside act as identifiers often called Receptor Molecules Proteins form transport tubes and binding sites. Binding sites are another form of Receptor Molecule. Different receptor molecules have specific shapes Receptor Molecule Functions • Some of the proteins and carbohydrate “trees” on the surface act as identifiers • Allow immune cells to detect non-self and abnormal cells • Detects useful materials (“food”) in environment for ingestion. • Allows cells to coordinated functions – e.g. neurotransmitters send nerve “signal” (impulse) to next cell. Transport Functions • Moving material in and out of the cell • Semipermeability = Some material diffuses through membrane • Semipermeability allows inside of cell to be different from outside • Other material is “pumped” through. • Still other material can’t get through (or “fools” the membrane into letting it in) Main Function: • Maintain the concentration of chemicals on the inside of the cell i.e. regulate the internal environment of the cell • Affect which materials go in and/or out But how?? “Get in there” • Receptor Mediated Endocytosis – Bringing large molecules or chunky bits into the cell. • Phagocytosis – Cellular “eating” • Pinocytosis – Cell “drinking” Animation