Weight Management: Overweight, Obesity, and Underweight I. Overweight Overweight (BMI 25-29.9) and obesity (≥ 30) are widespread health problems that are continuing to increase. Many refer to overweight and obesity as an epidemic. For good health, weight management is important. A. Fat Cell Development 1. Fat cell numbers a. Fat cell numbers increase most rapidly in later childhood and early puberty. b. Fat cell numbers increase in times of positive energy balance. c. Hyperplastic obesity 2. Fat cell size a. Fat cell sizes increase when energy intake exceeds expenditure. b. Hypertrophic obesity 3. The adverse effects of fat in non-adipose tissue are called lipotoxicity. B. Fat Cell Metabolism 1. Lipoprotein lipase promotes fat storage. 2. Gender differences a. Men are at increased risk for developing central obesity and women are at increased risk for lower body fat. b. Enzymes that break down fats affect men and women differently. C. Set-Point Theory 1. The body’s natural regulatory centers maintain homeostasis at set point. 2. The human body tends to maintain a certain weight. II. Causes of Obesity Obesity may not be as simple as food intake exceeding metabolic needs. Some factors, such as overeating and inactivity, are within our control. Genetic, hormonal and emotional factors may require professional intervention. A. Genetics 1. Leptin (also called the ob protein) a. Protein that acts as a hormone to increase energy expenditure and decrease appetite b. Produced by fat cells under the direction of the ob gene c. May be deficient in obese individuals d. More research is needed. 2. Ghrelin a. Protein that acts as a hormone to decrease energy expenditure and increase appetite b. Produced by stomach cells 1 c. Has an inverse relationship with PYY 3. Uncoupling Proteins a. Influence energy metabolism b. White adipose tissue stores fat to be used for energy. c. Brown adipose tissue stores fat to be used for heat. d. May oppose the development of obesity B. Environment – The gene pool of our population remains relatively unchanged. 1. Overeating a. Present and past eating influences current body weight. b. Increased availability of convenient food, large portions, and energy-dense foods 2. Physical Inactivity a. Modern technology replaces physical activities. b. Physical activity is important to allow people to eat enough food to get needed nutrients. III. Problems with Obesity Obesity problems depend on many factors such as the extent of overweight, age, health status and genetic makeup. Risk factors may differ among individuals. A. Health risks are evaluated using BMI, waist circumference and disease profiles. 1. Overweight people who are in good health may not need to lose weight. 2. Obese or overweight people with risk factors could improve health by losing weight or using other diet and exercise strategies. Risk factors include: a. Hypertension b. Cigarette smoking c. High LDL d. Low HDL e. Impaired glucose tolerance f. Family history of heart disease g. Men 45 years, women 55 years 3. Obese or overweight people with the following life-threatening-conditions may improve health by losing weight: a. Heart disease b. Type 2 diabetes c. Sleep apnea B. Perceptions and Prejudices 1. Social Consequences a. Prejudices and discrimination b. Judged on appearance rather than character c. Stereotyped as lazy and lacking self-control 2. Psychological Problems a. Feelings of rejection, shame and depression are common. b. Ineffective treatments can lead to a sense of failure. 2 C. Dangerous Interventions 1. Fad Diets a. False theories b. Inadequate diets c. Can be a danger to health d. \Ttypes of weight loss diets Low Carbohydrate aka High Protein Low Fat aka High Carbohydrate Very Low Calorie aka Modified Fast Novelty Diets Weight Loss Programs e. Why weight Loss Programs do not work Negative Impact Temporary Perfect- Orientation Project Mentality Do not Address Cause f. Consequences of Dieting Decrease in rate of weight loss Loss of lean tissue with fat loss Decrease in metabolism, 10-40% Decrease in Protein turnover Preoccupation with food Increase in irritability, moodiness Tires easier, less physical activity Apathy, depression g. Re-Feeding after weight loss Increase in pre-dieting food intake Preference for high fat foods Regain in weight, but greater increase in % BF Metabolism slow to return to normal Regain Weight quicker with each diet Increase in abdominal fat deposits Less likely to return to pre-diet physical activity Decrease in self-efficacy/esteem h. Recognizing an unsound diet Promotes Quick Weight Loss Limits Food Selection Testimonials or Famous People/Places Expensive Supplements or Products No Attempt to Permanently change eating or physical activity 3 Critical of Scientific Community‘ They know more, or something new i. Characteristics of a Sound Diet Nutritionally adequate yet low in calories Fit into current lifestyle Foods that are liked Slow rate of weight loss Followed for life D.. Predicting Weight Loss Success 1. Positive Affirmations a. Self esteem b. Self confidence c. Good attitude d. Positive outlook 2. Strong Motivation a. Desire or want b. Belief it is possible c. Commitment to doing it d. Positive attitude e. Persistence 3. Supportive Environment a. Family and friends b. Support group or organization c. Professional 4. Appropriate Behaviors a. Healthy eating b. Exercise that produces goal c. Changing problem behaviors 5. Changes in Body Shape a. Body Composition changes b. Circumference changes c. “Looks better”, Cloths fit better, etc. 2. Weight-Loss Products a. Ephedrine-containing products inhibit serotonin and suppress the appetite. Supplements containing Ephedra have been banned by the FDA due to potential health risks. b. Herbal laxatives do not prevent absorption. c. Current laws do not require safety tests and effectiveness tests for these products. 3. Other Gimmicks a. Don’t work b. There is no such thing as cellulite. 4 IV. Weight-Loss Strategies A life-long eating plan for good health, which includes nutritionally adequate eating, reasonable expectations, regular physical activity, and permanent lifestyle changes, is best for achieving permanent weight loss. Weight loss of 1-2 pounds per week or 10% of body weight in six months is safe. A. Eating Plans 1. Be Realistic about Energy Intake a. 300-500 kcalories/day reduction for BMI between 27 and 35 b. 500-1000 kcalories/day reduction for BMI 35 c. Dietary Guidelines should be followed. 2. Diet should be nutritionally adequate while avoiding excessive consumption. 3. Smaller portions are recommended to feel satisfied, not stuffed. 4. Eat foods of lower energy density, that are high in fiber, high in water and low in fat. 5. Water is important to increase fullness and reduce hunger. 6. Complex carbohydrates offer abundant vitamins, minerals and fiber with little fat. 7. Choose fats sensibly and reduce the quantity of fat. 8. Watch empty kcalories from sugar and alcohol. B. Physical Activity 1. An individual’s body weight as well as intensity and duration of activity influence energy expenditure. 2. Physical activity increases the amount of discretionary kcalories that can be consumed. 3. Metabolic rates can rise with daily vigorous activity. 4. Activity can decrease body fat and increase lean body mass. 5. Exercise may help to curb appetite. 6. Activity can reduce stress and improve self-esteem. 7. Choosing Activities a. Choose activities that you enjoy and are willing to do regularly. b. Low to moderate intensity for long duration is recommended. c. Daily routines can incorporate energy activities. 8. Spot Reducing a. Regular aerobic exercise and weight loss will help trouble spots. b. Strength training can improve muscle tone. c. Stretching can help flexibility. C. Behavior and Attitude 1. Behavior modification requires time and effort. 2. Awareness of behavior is the first key. 3. Changing behaviors one at a time works best. a. Do not grocery shop when hungry. b. Eat slowly. c. Exercise while watching television. 4. Personal attitudes toward food and eating must be understood. 5 5. Support groups may be helpful for some people. Aggressive Treatments of Obesity Individuals with clinically severe obesity and major medical problems may benefit from drugs or bariatric surgery. But changing and improving eating and exercise habits offer the greatest benefit. D. Drugs 1. Sibutramine suppresses the appetite and is most effective when used with a reduced kcalorie diet and increased physical activity. There are many side effects. 2. Orlistat blocks fat digestion and absorption. There are many side effects. 3. Other drugs are still under study. E. Surgery 1. Surgery is an option for those who have tried weight loss programs and failed, have a BMI ≥ 35, and are having health problems due to their weight. 2. Gastric surgery has short-term and long-term problems and requires compliance with dietary instructions. 3. Liposuction is a popular procedure that is primarily cosmetic but poses risk. F. Weight Maintenance 1. Successful weight-loss maintenance programs use different criteria so they are difficult to compare. 2. Vigorous exercise and careful eating plans are key. 3. Frequent self-monitoring is recommended. a. Food diary b. Exercise Journal c. Weekly weight d. Circumference changes G. Prevention 1. Eat regular meals and limit snacking. 2. Drink water in place of high-kcalorie beverages. 3. Select sensible portion sizes and limit daily energy intake to energy expended. 4. Limit sedentary activities and be physically active. H. Public health programs have been suggested to: 1. Develop safety standards for foods. 2. Control commercial advertising. 3. Control conditions under which foods are sold. 4. Control prices to reduce consumption. G. Predicting Weight Loss Success 6. Positive Affirmations a. Self esteem 6 b. Self confidence c. Good attitude d. Positive outlook 7. Strong Motivation a. Desire or want b. Belief it is possible c. Commitment to doing it d. Positive attitude e. Persistence 8. Supportive Environment a. Family and friends b. Support group or organization c. Professional 9. Appropriate Behaviors a. Healthy eating b. Exercise that produces goal c. Changing problem behaviors 10. Changes in Body Shape a. Body Composition changes b. Circumference changes c. “Looks better”, Cloths fit better, etc. VI. Underweight (BMI 18.5) Incidences of underweight and associated health problems are less prevalent than overweight and obesity problems. A. Problems of Underweight 1. Causes are diverse. 2. Energy demands may be great and foods are needed to support growth and physical activities. 3. Eating disorders are severe cases. B. Weight-Gain Strategies 1. Energy-dense foods can be included but choose fat wisely to avoid the associated cardiac risks. 2. Regular meals each day must become a priority. 3. Use large portions and expect to feel full. 4. Consume extra snacks between meals. 5. Juice and milk are easy ways to increase kcalories. 6. Exercising to build muscles will support increases in muscle mass. VI. The Latest and Greatest Weight-Loss Diet Again Fad diets do not offer safe or effective plans for weight loss. Diet recommendations should be research based. There are guidelines for identifying fad diets and weight-loss scams. 7 A. The Diet’s Appeal 1. There are many misconceptions and distortions of facts. 2. Results are not long lasting. B. The Diet’s Achievements 1. Don’t Count kCalories 2. Satisfy Hunger 3. Follow a Plan 4. Limit Choices C. The Diet’s Shortcomings 1. Too Much Fat 2. Too Much Protein 3. Too Little of Everything Else D. The Body’s Perspective – Adverse side effects of low-carbohydrate, ketogenic diets 1. Nausea 2. Fatigue 3. Constipation 4. Low blood pressure 5. Elevated uric acid 6. Stale, foul taste in the mouth 7. Fetal harm and stillbirth 1. Describe how body fat develops and suggest some reasons why it is difficult for an obese person to maintain weight loss. 2. What factors contribute to obesity? 3. List several aggressive ways to treat obesity and explain why such methods are not recommended for every overweight person. 4. Discuss reasonable dietary strategies suitable for achieving and maintaining a healthy body weight. 5. What are the benefits of increased physical activity in a weight-loss program? 6. Describe the behavioral strategies recommended for changing an individual’s dietary habits. What role does personal attitude play? 7. Describe strategies for successful weight gain. 8 Weight Management Medications1 Medication Classification Clinical Indication Megestrol Orexigenic Treatment of metastatic acetate agent breast cancer, metastatic (Megace) endometrial cancer; stimulation of appetite and promotion of weight gain in patients with wasting due to AIDS or cancer Dronabinol Orexigenic Prevention of nausea/ (Marinol) agent vomiting during cancer treatment; stimulation of appetite in AIDS patients Sibutramine hydrochloride monohydrate (Meridia) Orlistat (Xenical) Norepinephrine, Weight loss/ maintenance in serotonin and overweight patients dopamine inhibitor Lipase inhibitor Weight loss/ maintenance in overweight patients Monitoring Aspects Monitor for side effects: increased appetite and weight gain, swelling, hyperglycemia, headache, breast tenderness, impotence, decreased sexual desire, elevated blood pressure Monitor for interactions with alcohol and other depressant medications; side effects: dizziness, lightheadedness, or fainting; mental disturbances Monitor for side effects: elevated blood pressure or heart rate, allergic reactions, dizziness, drowsiness Monitor for improvement of blood glucose in diabetic patients; monitor for compliance with fat-restricted diet and daily multivitamin supplement . 9 Eating Attitudes Test Answer these questions using the following responses: A = Always U = Usually O = Often S= Sometimes R = Rarely N = Never Response _____ Score* _____ 1. I am terrified about being overweight. _____ _____ 2. I avoid eating when I am hungry. _____ _____ 3. I find myself preoccupied with food. _____ _____ 4. I have gone on eating binges where I feel that I may not be able to stop. _____ _____ 5. I cut my food into very small pieces. _____ _____ 6. I am aware of the calorie content of the foods I eat. _____ _____ 7. I particularly avoid foods with a high carbohydrate content. _____ _____ 8. I feel that others would prefer if I ate more. _____ _____ 9. I vomit after I have eaten. _____ _____ 10. I feel extremely guilty after eating. _____ _____ 11. I am preoccupied with a desire to be thinner. _____ _____ 12. I think about burning up calories when I exercise. _____ _____ 13. Other people think I am too thin. _____ _____ 14. I am preoccupied with the thought of having fat on my body. _____ _____ 15. I take longer than other people to eat my meals. _____ _____ 16. I avoid foods with sugar in them. _____ _____ 17. I eat diet foods. _____ _____ 18. I feel that food controls my life. _____ _____ 19. I display self-control around food. _____ _____ 20. I feel that others pressure me to eat. _____ _____ 21. I give too much time and thought to food. _____ _____ 22. I feel uncomfortable after eating sweets. _____ _____ 23. I engage in dieting behavior. _____ _____ 24. I like my stomach to be empty. _____ _____ 25. I enjoy trying new rich foods. _____ _____ 26. I have the impulse to vomit after meals. _____ *Scoring: 10 Total score 3 for never, 2 for rarely, 1 for sometimes, 0 for always, usually and often. Total scores under 20 points indicate abnormal eating behavior. Exploring Eating Habits To explore your eating habits, check all the answers that describe your food intake patterns. Then, consider possible areas for improvement. When do I usually eat? _______ At mealtime. _______ While studying. _______ While preparing meals or clearing the table. _______ When spending time with friends. _______ While watching TV or participating in other activities. _______ Anytime. Where do I usually eat? _______ At home at the kitchen or dining room table. _______ In the school cafeteria. _______ In fast-food places. _______ In front of the TV or while studying. _______ Wherever I happen to be when I’m hungry. Why do I usually eat? _______ It’s time to eat. _______ I’m hungry. _______ Foods look tempting. _______ Everyone else is eating. _______ Food will get thrown away if I don’t eat it. _______ I’m bored or frustrated. Changes I want to make: Source: U.S. Department of Agriculture, Dietary Guidelines and Your Health: Health Educator’s Guide to Nutrition and Fitness (Washington, DC, US Government Printing Office, 1992). 11 Exploring Food and Activity Choices Does your BMI fall between 18.5 and 24.9? If so, you may want to maintain your weight. If not, you may need to gain or lose weight to improve your fitness and health. Determine whether these food and activity choices are typical of your lifestyle. Food and activity choices Frequency per week Promote weight gain: Drink plenty of juice. Eat energy-dense foods. Eat large portions. Eat peanut butter crackers between meals. Eat three or more large meals a day. Promote weight loss: Drink plenty of water. Eat nutrient-dense foods. Eat slowly. Eat small portions. Limit snacks to healthful choices. Limit television watching. Participate in physical activity. Select low-fat foods. Share a restaurant meal or take home leftovers. 12 On the average, do your lifestyle choices promote weight gain, weight loss, or weight maintenance? Very-Low-kCalorie Diets Very-low-kcalorie-diets (VLCD) provide 800 kcalories, at least 1 gram of high-quality protein, per kilogram of body weight, little or no fat, and a minimum of 50 grams of carbohydrate (not enough to spare protein). Clients receive an assortment of vitamins and minerals from supplements. VLCD formulas are designed to be nutritionally adequate, but the body responds to this severe energy restriction as if the person were starving—conserving energy and preparing to regain weight at the first opportunity. Several changes occur in hormone concentrations, metabolic activities, fluid and electrolyte balances, and organ functions in the effort to meet the challenge of living on a much-less-than-adequate energy intake. For these reasons, a VLCD is appropriate only for short-term use (four months) and under close medical supervision. The table lists common side effects of VLCD. Weight losses on VLCD are dramatic. Unfortunately, weight regains are almost certain. With weight loss comes a slower BMR and slower fat oxidation—conditions that favor weight gain. Such rapid losses followed by steady gains are detrimental to both physical and psychological health. Possible Physical Consequences of Very-Low-kCalorie Diets Blood Blood carotene concentrations increase. Blood cholesterol concentrations increase. Blood urea concentrations increase. Cardiovascular/Respiratory Blood pressure declines. Carbon dioxide production declines. Cardiac output declines. Heart muscle atrophies. Heartbeat becomes irregular. Oxygen consumption declines. Pulse rate declines. Respiratory rate declines. Digestive Gallstones and kidney stones form. GI tract motility declines. Liver inflammation and fibrosis develop. Nausea, vomiting, diarrhea, abdominal discomfort, and constipation occur. Hormonal Menstrual irregularity develops. Sex drive is lost. Immunity Immune response diminishes. White blood cells decrease in number. Metabolic Basal metabolism declines. Bone mineral content shifts. Cold intolerance occurs. Dehydration may occur. Gout may occur. Ketosis develops. Lean body tissues are lost. Mineral and electrolyte imbalances occur. Nitrogen balance becomes negative. Other Body and breath odor (from ketone excretion) may become apparent. Hair falls out. Headaches occur. Lethargy, fatigue, and loss of stamina set in. Skin dries out. Sleeplessness may occur. Sudden death becomes possible. Sources: C. J. Field, R. Gougeon, and E. B. Marliss, American Journal of Clinical Nutrition 54 (1991): 123-129; K. N. Pavlou and coauthors, American Journal of Clinical Nutrition 49 (1989): 1115-1123; R. L. Atkinson, Low calorie diets and obesity, in Biotechnology and Nutrition, eds. D.D. Bills and S. D. Kung (Boston: Butterworth-Heinemann, 1992), pp. 29-45. 13 How to Change Behaviors to Support Weight Loss 1. To eliminate inappropriate eating cues: • Buy foods that are low in fat. • Shop when you are not hungry. • Serve low-fat meals. • Let other family members buy, store, and serve their own sweets (monitor children’s intakes). • Change channels or look away when food commercials appear on television. • Shop only from a list and stay away from convenience stores. • Carry appropriate snacks from home and avoid vending machines. 2. To suppress the cues you cannot eliminate: • Eat only in one place (at a table), and in one room; use plates, bowls, and eating utensils. • Clear plates directly into the garbage. • Create obstacles to the eating of problem foods (make it necessary to unwrap, cook, and serve each one separately). • Minimize contact with excessive food (serve individual plates, don’t put serving dishes on the table, and leave or clean the table when you have finished eating). • Make small portions of food look large by spreading food out and serving on small plates. • Control deprivation (eat regular meals, don’t skip meals, avoid getting tired, avoid boredom by keeping cues to fun activities in sight). 3. To strengthen the cues to appropriate eating and exercise: • Encourage others to eat appropriate foods with you. • Keep your favorite appropriate foods in the front of the refrigerator. • Learn appropriate portion sizes and prepare one portion at a time. • Establish specific times for meals and snacks. • Prepare foods attractively. • Keep your walking shoes (ski poles, tennis racket) by the door. 4. To engage in desired eating or exercise behaviors: • Eat only at planned times; plan not to eat after a specified time (say, 7:00 or 8:00 p.m.). • Slow down (pause several times during a meal, put down utensils between mouthfuls, chew thoroughly before swallowing, swallow before reloading the fork, always use utensils). • Leave some food on the plate. • Engage in no other activities while eating (such as reading or watching television). • Move more (shake a leg, pace, fidget, flex your muscles). • Join in and exercise with a group of active people. 5. To arrange or emphasize negative consequences of inappropriate eating: • Eat your meals with other people. • Ask that others respond neutrally when you deviate from your plan (make no comment). This is a negative consequence because it withholds attention. • If you slip, don’t punish yourself. 6. To arrange or emphasize positive consequences of appropriate behaviors: • Update records of food intake, exercise, and weight change regularly. • Arrange for rewards for each unit of behavior change or weight loss. • Ask family and friends for reinforcement (praise and encouragement). 14