1 BSC 2085 Chapter 3 Class Notes, Part 2 Summer 2010 What are the two major phases of the Cell Cycle? What are 3 subphases of the Interphase? ____________________ enzyme untwists the DNA helix and exposes the _________________ DNA strands. Each DNA strand serves as a _____________ for building a ___________ DNA strand. The base sequence of the new DNA strand is __________________ to the base sequence of the original DNA strand. DNA replication is _______________________ because only one strand of the original DNA is found in each of the two ___________ DNA molecules. In which 3 cell types does mitosis not occur? What are the 2 events of Cell Division? What are the 4 phases of mitosis? What are 4 things that happen during Prophase? What is 1 thing that happens during Metaphase? What is 1 thing that happens during Anaphase, the shortest phase of cell division? What are 4 things that happen during Telophase? What happens during Cytokinesis? What is the role of MPF? What are some other “go” signals for cell division? What is the role of contact inhibition? What is the role of functional p53? With what disease is dysfunctional p53 correlated? ____________ is the master blueprint for protein synthesis. A ___________ is a segment of DNA that codes for one protein. A ___________ is three base segment of DNA that codes for one amino acid. What is the sequence of the “start” codon of DNA? What are the 3 sequences of the “stop” codons of DNA? How many codons are there? What are the 3 major steps for creating the Flow of Information of Protein Synthesis? What are the 3 main types of RNA and what are their roles? RNA _______________ the DNA base sequence. 2 After special processing that turns RNA into messenger RNA, it leaves the ____________ and binds to a _____________ in the cytosol. The ______________ of transfer RNA is complementary to the codon of mRNA. The codon of mRNA actually codes for the _____________________that is attached to the tRNA. What are the three steps of mRNA transcription? 3 Translation converts the _______________________________ of nucleic acids into the _______________________ of proteins How do amino-acyl tRNA synthetase, tRNA, and an amino acid interact during the first steps of translation? What are the roles of the ribosome, mRNA and tRNA (bound to amino acid) in completing translation? What are the 4 steps describing the Flow of Information for Protein Synthesis? What are the 5 major steps of Translation? What causes an RNA-ribosome complex to attach to the ER? What happens to the protein that is extruded into the ER? Where can you find “junk” regions of DNA? What does “anti-sense” RNA do? What is an Riboswitch and what does it do? __________________________ break down proteins into amino acids and are especially active during ________________. What is a key feature in cell differentiation during development? What is apoptosis and when does it occur? 4 5 6 7 8 9 10