Name: _______________________________________________ Date: __________ Block: _________ Honors Learning Targets and Study Guide DNA, RNA and Protein Synthesis (Chapter 12) Learning Target 1: The Structure and Function of DNA (Bio 5 e, f, g) o I can describe the contributions of several scientists (discussed in class) and their contribution to our understanding of the structure and function of DNA. o I can describe how DNA is a polymer of nucleotides and that each nucleotide is identified by the nitrogenous base it contains: adenine (A), guanine (G), cytosine (C), and thymine (T). o I can describe the structure of DNA. DNA is a double-stranded molecule. The strands are connected by complementary nucleotide pairs (A/T and C/G) like rungs on a ladder. That ladder is twisted to form a double helix. Learning Target 2: How DNA Replicates (Bio 5 e, f, g) o I can explain why it is necessary for the instructions (DNA) to be duplicated and when during the cell cycle this process occurs. o I can describe the process of DNA replication, enzymes involved in the unzipping of the double helix, and those responsible for the building a new DNA molecule. Learning Target 3: The Structure and Function of RNA (Bio 5 e, f, g) o I can describe the purpose of RNA and how it is a single-stranded polymer composed of four types of nucleotides. o I can compare and contrast DNA and RNA in regards to structure and function. Learning Target 4: The Process of Protein Synthesis (Bio 5 e, f, g) o I can explain how information encoded in DNA molecules provides the instructions for assembling protein molecules through transcription (DNA to mRNA) and translation (mRNA to protein synthesis). Learning Target 5: The Impact of Mutations on Protein Synthesis o I can explain how inserting, deleting, or substituting DNA segments can alter genes and ultimately the production of proteins. o I can describe the consequence of adding or deleting entire chromosomes, which can possibly result in a genetic disorder such as Trisomy 21 (Down syndrome). Important Vocabulary in Mastering Learning Targets: Vocabulary Nucleotide Base Pairing Chromatin Histones Definition Picture or Word Association Name: _______________________________________________ Date: __________ DNA Polymerase III DNA Polymerase I Helicase Ligase Lagging Strand mRNA rRNA tRNA Transcription RNA Polymerase Codon Translation Anticodon Point Mutation Frameshift Mutation Chromosome Mutations Block: _________ Name: _______________________________________________ Date: __________ Block: _________