Global Burden of Disease 2004 Update: Selected figures and tables Health Statistics and Informatics Department Health Statistics and Informatics Leading Causes of Mortality and Burden of Disease world, 2004 Mortality % 1. Ischaemic heart disease 12.2 2. Cerebrovascular disease 9.7 3. Lower respiratory infections 7.1 4. COPD 5.1 5. Diarrhoeal diseases 3.7 6. HIV/AIDS 3.5 7. Tuberculosis 2.5 8. Trachea, bronchus, lung cancers 2.3 9. Road traffic accidents 2.2 10. Prematurity, low birth weight 2.0 Health Statistics and Informatics DALYs % 1. Lower respiratory infections 6.2 2. Diarrhoeal diseases 4.8 3. Depression 4.3 4. Ischaemic heart disease 4.1 5. HIV/AIDS 3.8 6. Cerebrovascular disease 3.1 7. Prematurity, low birth weight 2.9 8. Birth asphyxia, birth trauma 2.7 9. Road traffic accidents 2.7 10. Neonatal infections and other 2.7 Distribution of age at death and numbers of deaths, world, 2004 Health Statistics and Informatics Per cent distribution of age at death by region, 2004 Health Statistics and Informatics Distribution of deaths in the world by sex, 2004 Health Statistics and Informatics Distribution of deaths by leading cause groups, males and females, world, 2004 Health Statistics and Informatics Child mortality rates by cause and region, 2004 Health Statistics and Informatics Distribution of child deaths for selected causes by selected WHO region, 2004 Health Statistics and Informatics Distribution of causes of death among children aged under five years and within the neonatal period, 2004 Health Statistics and Informatics Mortality rates among men and women aged 15–59 years, region and cause-of-death group, 2004 Health Statistics and Informatics Adult mortality rates by major cause group and region, 2004 Cardiovascular diseases High income Cancers Other noncommunicable diseases Western Pacific Injuries HIVAIDS Americas Other infectious and parasitic diseases Maternal and nutritional conditions Eastern Mediterranean South East Asia Europe Africa 0 Health Statistics and Informatics 2 4 6 8 10 Death rate per 1000 adults aged 15–59 years 12 Comparison of the proportional distribution of deaths and YLL by region, 2004 Health Statistics and Informatics Comparison of the proportional distribution of deaths and YLL by leading cause of death, 2004 Health Statistics and Informatics YLL, YLD and DALYs by region, 2004 Health Statistics and Informatics Burden of disease by broad cause group and region, 2004 Health Statistics and Informatics Age distribution of burden of disease by income group, 2004 Health Statistics and Informatics Leading causes of disease burden for women aged 15–44 years, high-income countries, and lowand middle-income countries, 2004 Health Statistics and Informatics Major causes of disease burden for women aged 15–59 years, high-income countries, and low- and middle-income countries by WHO region, 2004 Health Statistics and Informatics Age-standardized DALYs for noncommunicable diseases by major cause group, sex and country income group, 2004 Health Statistics and Informatics Burden of injuries (DALYs) by external cause, sex and WHO region, 2004 Health Statistics and Informatics Global projections for selected causes, 2004 to 2030 12 Cancers Deaths (millions) 10 Ischaemic HD Stroke 8 6 Acute respiratory infections 4 Road traffic accidents Perinatal HIV/AIDS TB Malaria 2 0 2000 2005 2010 2015 2020 2025 2030 Updated from Mathers and Loncar, PLoS Medicine, 2006 Health Statistics and Informatics Projected deaths by cause and income, 2004 to 2030 30 Intentional injuries Other unintentional Road traffic accidents Deaths (millions) 25 Other NCD 20 Cancers 15 CVD 10 Mat//peri/nutritional 5 Other infectious HIV, TB, malaria 0 2004 2015 2030 High income Health Statistics and Informatics 2004 2015 2030 Middle income 2004 2015 2030 Low income Ten leading causes of burden of disease, world, 2004 and 2030 Health Statistics and Informatics