Vitamins Chapter 6 What are vitamins? • Organic molecules • Essential for human survival • Exist in water and fat soluble forms Photo © AbleStock Vitamin Classification Fat Soluble • A, D, E, K • Do not dissolve in water • Require dietary fat for transport in blood • Excess can be stored in fat tissues of body • Higher potential for toxicity - supplements Water Soluble • B complex, C • Dissolve in water • Easily transported in blood • Excess is excreted in urine • Low potential for toxicity • Coenzymes B-Complex Vitamin: Thiamine • Also known as B1 • Coverts Pyruvate into Acetyl Co-A – Synthesis of ATP • RDA/AI – .5 mg/1,000 kcal expended Source: USDA B-Complex Vitamin: Thiamine • Deficiency – BeriBeri – Degeneration of body • Nervous system • Circulatory system • Good Sources – Fish • Trout – Pork – Seeds • Sunflower – Bread • Wheat – Asparagus – Nuts • Macadamia – Edamame B-Complex Vitamin: Riboflavin • Also known as B2 • Functions: – Releasing energy from CHO – Body growth – RBC production Source: USDA B-Complex Vitamin: Riboflavin (continued) • Minimal research • Medical uses on athletes • Supplements are not needed with a balanced diet • Rarely see deficiency Source: USDA B-Complex Vitamin: Riboflavin (continued • Good Sources – Liver • Beef • Chicken – Dairy – Nuts – Milk – Eggs – Green leafy vegetables – Legumes B-Complex Vitamin: Niacin • Also known as B3 • Functions: – Energy metabolism • RDA/AI: – Men = 16 mg – Women = 14 mg – UL = 35 mg Source: USDA B-Complex Vitamin: Niacin (continued) • Absorbed in intestines • Good sources and stomach – Fish • Yellow Fin Tuna • Possible medical uses – Poultry • Possible side effects – Liver – Deficiency – Over Dose • Lamb – Peanuts – Mushrooms • Portobello – Avocado Source: USDA B-Complex Vitamin: B6 • Functions: – Glycogen metabolism – Protein Metabolism • Protein intake – Neural function • Pregnancy • Infancy Source: USDA B-Complex Vitamin: B6 (continued) • Lower Homocysteine levels • Component of 100 enzymes that facilitate • • • • Breakdown of glycogen Synthesis of AA Convert Trytophan Produce RBC’s hemoglobin ring • Produce WBC Source: USDA B-Complex Vitamin: B6 (continued • Deficiency – uncommon • Toxicity – Uncommon from food intake • Good Sources – Nuts and Seeds • Sunflower, Pistachio – Fish • Tuna – Poultry – Fruit • Prunes • Bananas – Avocado B-Complex Vitamin: B12 • Also known as cobalamin • Functions: – Energy production – Tissue growth and development – Nervous and cardiovascular health – RBC Source: USDA B-Complex Vitamin: B12 • Found only animal foods • Lower Homocysteine levels • Concern • Older athletes • Vegetarians • Good Sources – Shellfish • Clams – Meat • Beef liver – Eggs – Cheese • Swiss – Poultry Source: USDA B-Complex Vitamin: B12 • Deficiency – Rapid HR, breathing – Anemia • Large abnormal RBC • Toxicity – rare • Deficiency can result in permanent nerve damage B-Complex Vitamin: Folate • Also known as folic acid • Functions: – DNA synthesis – Cell division (e.g., neural tube defects) – Tissue repair – RBC maturation • RDA/AI: – 400 µg – UL 1,000 µg Source: USDA B-Complex Vitamin: Folate (continued) • Important at the • Toxic levels- rare moment of conception • Lowers homocysteine levels • Anemia • Energy levels Source: USDA Folate - continued • 1998 federal law required folate to be added to – – – – – – Cold cereals Flour Bread Pasta Baked goods Crackers Folate – continued Good Sources • Legumes • Green leafy – – – – Spinach Romaine Broccoli Asparagus • Avocado • Tropical fruit – Mango B-Complex Vitamin: Biotin • Functions: – DNA synthesis – Aerobic energy production from CHOs, fats, proteins – Facilitates Gluconeogenesis Biotin - continued • Deficiency is rare • No known toxic effects • Good Souces – Nuts and seeds • Peanuts • Almonds – Eggs – Sweet potatoes • Has been used for diabetes (type 2) and for treatment of brittle nails B-Complex Vitamin: Pantothenic Acid • Functions: – Aerobic energy production from CHOs, fats, proteins – Aids substrates into the krebs cycle Source: USDA Pantothenic Acid • Deficiency – rare • Toxic effects - rare • Good Sources – Mushrooms • Shitake • Crimini – – – – Avocado Sweet potato Yogurt Chicken Vitamin C • Ascorbic acid or ascorbate • Functions: – Collagen synthesis – Immune function – Antioxidant • RDA/AI: – Men = 90 mg – Women = 75 mg – UL = 2,000 mg Source: USDA Vitamin C (continued) • Enhances iron absorption • Healing of wounds • Formation of scars • Formation of hormones and neurotransmitters • >2,000 mg can cause side effects Source: USDA Vitamin C - continued • Deficiency – – – – Scurvy Swollen gums Fatigue Rid body of cholesterol – Immunity • Toxic effects >2000 mg – – – – Nausea Abdominal cramps Nose bleeds Kidney stones Vitamin C continued • Good Sources – Fruit • • • • • • Papaya Orange Pineapple Kiwi Strawberry Cantaloupe – Bell pepper – Broccoli – Spinach Vitamin A • Known as retinoids • Consumed as retinoids(animal) or carotenoids (plant) • Functions: – Vision – Cell differentiation – stem cells – Immune function • RDA/AI: – Men = 900 µg RAE (retinol activity equivalent) – Women =700 µg RAE – UL = 3,000 µg RAE Vitamin A (continued) • Especially important to athletes to repair damaged tissue during training • Antioxidant • Consume food sources vs. supplements (decrease possible toxicity) Source: USDA Vitamin D • “Sunshine” vitamin • Calcitriol • Functions: – Controls blood calcium levels – Regulating levels of phosphorous – Bone growth/development • RDA/AI: – AI = 5 to 15 µg – UL = 50 µg • 80 to 90% synthesized by the body Vitamin D (continued) • Supplements • Fortified foods • Premenopausal and – Dairy postmenopausal – Juice • Vitamin D with – Cereal calcium and magnesium can decrease osteoporosis Source: USDA Vitamin D continued • Deficiency – Could be caused by • • • • • Diet Enough sunlight Kidneys GI tract Obesity – Osteoporosis – Rickets • Toxicity – Uncommon – Megadoses Vitamin D continued • Good Sources – – – – – Salmon Sardines Tuna Milk Eggs • Found in small amounts in foods Vitamin E Functions: – Antioxidant – Skin and connective tissue • RDA/AI (alpha tocopherol): – RDA = 15 mg – UL = 1,000 mg • Anti-aging – Protects cell membranes – Protects genetic material from free radicals Source: USDA Vitamin E (continued) • High doses of Vit. E can affect Vit. K blood clotting function • Serious bleeding in the brain can result with high doses Source: USDA Vitamin E continued • Deficiency – Rare – Very low weight pre-mature babies – Fat malabsorption • Toxicity – Rare – Reduces ability for blood clotting Vitamin E • Good sources – – – – – – Vegetable oil Cereal Meat Poultry Tofu shrimp Vitamin K • Also known as quinones • Functions: – Blood clotting – Bone mineralization • AI:no RDA only AI – Men = 120 µg – Women = 90 µg – UL not established Source: USDA Vitamin K (continued) • Without Vitamin K even a small cut could be life threatening • Newborns receive Vitamin K as a standard procedure, lack the bacteria that produces Vit K Source: USDA Vitamin K continued • Deficiency – Uncommon – Impairs blood clotting – Athletes more likely to have bruising • Toxicity – rare Vitamin K • Good sources – Green leafy – Herbs • Basil • Thyme – Prunes – Tofu – Cheese • swisss – Eggs What are phytochemicals? • Chemical substances from plants. • Phyto means “plant” • Approx. 50 phytochemicals are consumed in typical American diet. • Consumption is associated with decreased risk for cardiovascular disease and cancers. • Common sources are fruits, vegetables and grains. Tips for Increasing Phytochemical Intake • Serve hot or cold green tea with meals. • Keep red or green grapes washed and ready in the refrigerator for snacks. • Use tomato sauces, pastes, and spaghetti sauce as a basis for meals. • Sprinkle nuts and seeds on salads. • Use garlic in cooking, dressings, marinades, and sauces. Tips for Increasing Phytochemical Intake • Complement all meals with one or two fruits or vegetables • Use whole grain foods more often than processed grains • Try a new grain recipe that uses bulgar, barley, or oats • Eat fruit for dessert such as a baked apple, chopped melon or chilled berries