Publications for Douglas Begg 2016

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Publications for Douglas Begg

2016

Swift, B., Huxley, J., Plain, K., Begg, D., de

Silva, K., Purdie (Williams), A., Whittington, R.,

Rees, C. (2016). Evaluation of the limitations and methods to improve rapid phage-based detection of viable Mycobacterium avium subsp. paratuberculosis in the blood of experimentally infected cattle. BMC Veterinary

Research , 12(115). <a href="http://dx.doi.org/10.1186/s12917-016-072

8-2">[More Information]</a>

Swift, B., Huxley, J., Plain, K., Begg, D., de

Silva, K., Purdie (Williams), A., Whittington, R.,

Rees, C. (2016). Evaluation of the limitations and methods to improve rapid phage-based detection of viable Mycobacterium avium subsp. paratuberculosis in the blood of experimentally infected cattle. BMC Veterinary

Research , 12, 115. <a href="http://dx.doi.org/10.1186/s12917-016-072

8-2">[More Information]</a>

2015 de Silva, K., Plain, K., Begg, D., Purdie

(Williams), A., Whittington, R. (2015). CD4+

T-cells, T-cells and B-cells are associated with lack of vaccine protection in Mycobacterium avium subspecies paratuberculosis infection.

Vaccine , 33, 149-155. <a href="http://dx.doi.org/10.1016/j.vaccine.2014.1

0.082">[More Information]</a>

Plain, K., Waldron, A., Begg, D., de Silva, K.,

Purdie (Williams), A., Whittington, R. (2015).

Efficient, validated method for the detection of mycobacterial growth in liquid culture media using bead-beating, magnetic particle nucleic acid isolation and quantitative PCR. Journal of

Clinical Microbiology , 53(4), 1121-1128. <a href="http://dx.doi.org/10.1128/JCM.03521-14"

>[More Information]</a>

Gulliver, E., Plain, K., Begg, D., Whittington, R.

(2015). Histopathological Characterization of

Cutaneous Delayed-type Hypersensitivity and

Correlations with Intestinal Pathology and

Systemic Immune Responses in Sheep with

Paratuberculosis. Journal of Comparative

Pathology , 153, 67-80. <a href="http://dx.doi.org/10.1016/j.jcpa.2015.05.00

5">[More Information]</a>

Thirunavukkarasu, S., de Silva, K., Begg, D.,

Whittington, R., Plain, K. (2015). Macrophage polarization in cattle experimentally exposed to

Mycobacterium avium subsp. paratuberculosis.

Pathogens and Disease , 73(9), 1-9. <a

Publications for Douglas Begg href="http://dx.doi.org/10.1093/femspd/ftv085">

[More Information]</a>

Begg, D., de Silva, K., Plain, K., Purdie

(Williams), A., Dhand, N., Whittington, R.

(2015). Specific faecal antibody responses in sheep infected with Mycobacterium avium subspecies paratuberculosis. Veterinary

Immunology and Immunopathology , 166(3-4),

125-131. <a href="http://dx.doi.org/10.1016/j.vetimm.2015.0

6.011">[More Information]</a>

Johansen, M., Purdie (Williams), A., de Silva,

K., Plain, K., Begg, D., Whittington, R. (2015).

The role of intracellular cholesterol within macrophages exposed to Mycabacterium Avium subsp. paratuberculosis. 43rd Annual Scientific

Meeting of the Australian Society for

Microbiology , N/A: N/A.

2014

Whittington, R., Whittington, A., Waldron, A.,

Begg, D., de Silva, K., Purdie (Williams), A.,

Plain, K. (2014). A liquid medium (M7H9C) for routine culture of Mycobacterium Avium Subsp

Paratuberculosis to replace Bactec 12. 12th

International Colloquium on Paratuberculosis ,

Italy: N/A.

Whittington, R., Whittington, A., Waldron, A.,

Begg, D., de Silva, K., Purdie (Williams), A.,

Plain, K. (2014). A liquid medium (M7H9C) for routine culture of Mycobacterium Avium Subsp.

Paratuberculosis to replace Bactec 12. 12th

International Colloquium on Paratuberculosis ,

Italy: N/A.

Plain, K., Marsh, I., Begg, D., Purdie (Williams),

A., de Silva, K., Whittington, R. (2014). A new molecular diagnostic test for Johne's disease; from lab to national uptake. 12th International

Colloquium on Paratuberculosis , Italy: N/A.

Gurung, R., Begg, D., Purdie (Williams), A.,

Whittington, R. (2014). Antigenicity in sheep of synthetic peptides derived from stress-regulated

Mycobacterium avium subsp. paratuberculosis proteins and comparison with recombinant protein and complex native antigens. Veterinary

Immunology and Immunopathology , 158(1-2),

46-52. <a href="http://dx.doi.org/10.1016/j.vetimm.2013.0

5.016">[More Information]</a>

Gurung, R., Purdie (Williams), A., Whittington,

R., Begg, D. (2014). Cellular and humoral immune responses in sheep vaccinated with candidate antigens MAP2698c and MAP3567 from Mycobacterium avium subspecies paratuberculosis. Frontiers in Cellular and

Infection Microbiology , 14(93), 1-8. <a href="http://dx.doi.org/10.3389/fcimb.00093">[

More Information]</a>

Purdie (Williams), A., Begg, D., de Silva, K.,

Plain, K., Whittington, R. (2014). Consistent gene expression panels identified at early time points that predict clinical outcomes of JD in

Sheep. 12th International Colloquium on

Paratuberculosis , Italy: N/A.

Purdie (Williams), A., Begg, D., de Silva, K.,

Plain, K., Whittington, R. (2014). Consistent gene expression panels identified at early time points that predict clinical outcomes of JD in sheep. 12th International Colloquium on

Paratuberculosis , Italy: N/A.

Eppleston, J., Begg, D., Dhand, N., Watt, B.,

Whittington, R. (2014). Environmental Survival of mycobacterium avium subsp. paratuberculosis in Different Climatic Zones of Eastern Australia.

Applied and Environmental Microbiology , 80(8),

2337-2342. <a href="http://dx.doi.org/10.1128/AEM.03630-13"

>[More Information]</a>

Thirunavukkarasu, S., Plain, K., de Silva, K.,

Begg, D., Whittington, R., Purdie (Williams), A.

(2014). Expression of genes associated with cholesterol and lipid metabolism identified as a novel pathway in the early pathogenesis of

Mycobacterium avium subspecies paratuberculosis - infection in cattle. Veterinary

Immunology and Immunopathology , 160(3-4),

147-157. <a href="http://dx.doi.org/10.1016/j.vetimm.2014.0

4.002">[More Information]</a>

Plain, K., Marsh, I., Waldron, A., Galea, F.,

Whittington, A., Saunders, V., Begg, D., de

Silva, K., Purdie (Williams), A., Whittington, R.

(2014). High-Throughput Direct Faecal PCR

Assay to detection of Mycobacterium avium subspecies paratuberculosis in sheep and cattle.

Journal of Clinical Microbiology , 52(3),

745-757. <a href="http://dx.doi.org/10.1128/JCM.03233-13"

>[More Information]</a>

Gurung, R., Begg, D., Purdie (Williams), A.,

Bach, H., Whittington, R. (2014).

Immunoreactivity of protein tyrosine phosphatase A (PtpA) in sera from sheep infected with Mycobacterium avium subspecies paratuberculosis. Veterinary Immunology and

Immunopathology , 160, 129-132. <a href="http://dx.doi.org/10.1016/j.vetimm.2014.0

3.013">[More Information]</a>

Begg, D., Plain, K., de Silva, K., Purdie

(Williams), A., Whittington, R. (2014). John's disease; a mycobacterial infection of ruminants.

The Australian Society for Microbiology , N/A:

N/A.

Begg, D. (2014). Johne’s disease; a

Mycobacterial infection of Ruminants. National

Institute for Mathematical and Biological

Publications for Douglas Begg

Synthesis seminar series , N/A: N/A.

Gurung, R., Begg, D., Purdie (Williams), A., de

Silva, K., Bannantine, J., Whittington, R. (2014).

Lymphoproliferative and Gamma Interferon responses to stress-regulated Mycobacterium avium subspecies paratuberculosis recombinant proteins. Clinical and Vaccine Immunology ,

21(6), 831-837. <a href="http://dx.doi.org/10.1128/CVI.00775-13">

[More Information]</a>

Gurung, R., Purdie (Williams), A., Begg, D., de

Silva, K., Plain, K., Whittington, R. (2014).

Mycobacterium Avium subspecies

Paratuberculosis stressome and diagnostic significance: A review and Meta-analysis. 12th

International Colloquium on Paratuberculosis ,

Italy: N/A.

Begg, D., Plain, K., de Silva, K., Purdie

(Williams), A., Whittington, R. (2014).

Production of Mucosal antibody in response to

Paratuberculosis infection. 12th International

Colloquium on Paratuberculosis , Italy: N/A.

de Silva, K., Purdie (Williams), A., Plain, K.,

Begg, D., Whittington, R. (2014). Understanding vaccine failure I relation to immune parameters in map infection. 12th International Colloquium on Paratuberculosis , Italy: N/A.

de Silva, K., Purdie (Williams), A., Plain, K.,

Begg, D., Whittington, R. (2014). Understanding vaccine failure in relation to immune parameters in map infection. 12th International Colloquium on Paratuberculosis , Italy: N/A.

2013

Gurung, R., Begg, D., Purdie (Williams), A.,

Bannantine, J., Whittington, R. (2013).

Antigenicity of Recombinant Maltose Binding

Protein-Mycobacterium avium subsp.

Paratuberculosis Fusion Proteins with and without Factor Xa Cleaving. Clinical and

Vaccine Immunology , 20(12), 1817-1826. <a href="http://dx.doi.org/10.1128/CVI.00596-13">

[More Information]</a> de Silva, K., Browne, S., Begg, D., Whittington,

R., Emery, D. (2013). Apoptosis of lymph node and peripheral blood cells in ovine Johne's disease. Veterinary Immunology and

Immunopathology , 156(1-2), 82-90. <a href="http://dx.doi.org/10.1016/j.vetimm.2013.0

8.001">[More Information]</a> de Silva, K., Begg, D., Plain, K., Purdie

(Williams), A., Kawaji, S., Dhand, N.,

Whittington, R. (2013). Can early host responses to mycobacterial infection predict eventual disease outcomes? Preventive Veterinary

Medicine , 112, 203-212. <a href="http://dx.doi.org/10.1016/j.prevetmed.201

3.08.006">[More Information]</a>

de Silva, K., Begg, D., Purdie (Williams), A.,

Plain, K., Whittington, R. (2013). Comparison

Of The Host Immune Response To Gudair®

Vaccination And Map Exposure. International

Veterinary Immunology Syposium .

Whittington, R., Whittington, A., Waldron, A.,

Begg, D., de Silva, K., Purdie (Williams), A.,

Plain, K. (2013). Development and validation of a liquid medium (M7H9C) for routine culture of

Mycobacterium avium subsp. paratuberculosis to replace modified Bactec 12B medium. Journal of

Clinical Microbiology , 51(12), 3993-4000. <a href="http://dx.doi.org/10.1128/JCM.01373-13"

>[More Information]</a>

Begg, D., Whittington, R. (2013). Johne’s disease in sheep. 8th International Sheep

Veterinary Congress , Rotorua, New Zealand:

New Zealand Veterinary Association Inc.

Miller, Y., Collins, A., Emery, D., Begg, D.,

Smits, R., Holyoake, P. (2013). Piglet performance and immunity is determined by the parity of both the birth dam and the rearing dam.

Animal Production Science , 53(1), 46-51. <a href="http://dx.doi.org/10.1071/AN12063">[Mo re Information]</a>

Bower (Goldsmith), K., Begg, D., Whittington,

R. (2013). Tissue localisation of Mycobacterium avium subspecies paratuberculosis following artificially induced intracellular and naked bacteraemia. Veterinary Microbiology , 162(1),

112-118. <a href="http://dx.doi.org/10.1016/j.vetmic.2012.03

.007">[More Information]</a>

2012

Plain, K., Marsh, B., Begg, D., Galea, F.,

Waldron, A., Whittington, A., Whittington, R.

(2012). A new high-throughput direct faecal

PCR test for Johnes diesease. IVVDC 2012 ,

Queensland: N/A.

Plain, K., Marsh, I., Begg, D., Galea, F.,

Waldron, A., Whittington, A., Whittington, R.

(2012). A new high-throughput direct faecal

PCR test for Johne’s disease. 6th International

Veterinary Vaccines and Diagnostics

Conference , N/A: N/A.

Whittington, R., Begg, D., de Silva, K., Plain, K.,

Purdie (Williams), A. (2012). Comparative immunological and microbiological aspects of paratuberculosis as a model mycobacterial infection. Veterinary Immunology and

Immunopathology , 148(1-2), 29-47. <a href="http://dx.doi.org/10.1016/j.vetimm.2011.0

3.003">[More Information]</a>

Purdie (Williams), A., Begg, D., de Silva, K.,

Plain, K., Whittington, R. (2012). Differential gene expression changes associated with sub-clinical Mycobacterium avium subspecies

Publications for Douglas Begg paratuberculosis infection in cattle: a transcriptomic study. Immunology 2012 , usa:

N/A.

de Silva, K., Begg, D., Plain, K., Purdie

(Williams), A., Kawaji, S., Dhand, N.,

Whittington, R. (2012). Early biomarkers of resistance and susceptibility to mycobacterial disease. Immunology 2012 , usa: N/A.

Plain, K., Begg, D., de Silva, K., Purdie

(Williams), A., Whittington, R. (2012).

Enhancement of the interferon gamma assay to detect paratuberculosis using interleukin-7 and interleukin-12 potentiation. Veterinary

Immunology and Immunopathology , 149(1-2),

28-37. <a href="http://dx.doi.org/10.1016/j.vetimm.2012.0

5.023">[More Information]</a>

Eppleston, J., Begg, D., Curran, G., Dhand, N.,

Watt, B., Whittington, R. (2012). Envoronmental survival of MAP across New South Wales. 94th

District veterinarian's Conference , Wollongong:

District veterinarian's association.

Purdie (Williams), A., Plain, K., Begg, D., de

Silva, K., Whittington, R. (2012). Expression of genes associated with the antigen presentation and processing pathway are consistently regulated in early Mycobacterium avium subsp. paratuberculosis infection. Comparative

Immunology, Microbiology and Infectious

Diseases: the international journal for medical and veterinary researchers and practitioners ,

35(2), 151-162. <a href="http://dx.doi.org/10.1016/j.cimid.2011.12.

007">[More Information]</a>

Begg, D., Plain, K., de Silva, K., Purdie

(Williams), A., Whittington, R. (2012).

Extension of the storage time of blood in interferon gamma assays to diagnose paratuberculosis: combination of IL-7 and IL-12 stimulation. 6th International Veterinary

Vaccines and Diagnostics Conference , N/A:

N/A.

Begg, D., Plain, K., de Silva, K., Purdie

(Williams), A., Whittington, R. (2012).

Extension of the storage time of blood in interferon gamma assays to disgnose paratuberculosis: combination of II-7 and II-12 stimulation. 4th European Veterinary

Immunology Workshop (EVIW) , N/A: N/A.

Begg, D., Plain, K., de Silva, K., Purdie

(Williams), A., Whittington, R. (2012).

Extension of the storgage time of blood in interferon gamma assay to diagnose paratuberculosis: reporting guidelines. 11th

International Colloquium on Paratuberculosis ,

N/A: N/A.

de Silva, K., Begg, D., Plain, K., Purdie

(Williams), A., Kawaji, S., Whittington, R.

(2012). Immune profiles and faecal shedding of

Mycobacterium avium paratuberculosis indicate eventual severity of Johne's Disease. 11th

International Colloquium on Paratuberculosis ,

N/A: N/A.

Dukkipati, V., Ridler, A., Buddle, B.,

Hedgespeth, B., Begg, D., Whittington, R.,

Murray, A. (2012). Immune response profiles of lambs infected with a lyophilised pure culture seed-stock of mycobacterium avium subspecies paratuberculosis. 11th International Colloquium on Paratuberculosis , N/A: N/A.

Gurung, R., Purdie (Williams), A., Begg, D.,

Whittington, R. (2012). Immunogenicity evaluation of in silico identified MAP recombinant proteins that were upregulated under stress conditions. 11th International

Colloquium on Paratuberculosis , N/A: N/A.

Gurung, R., Begg, D., Purdie (Williams), A.,

Whittington, R. (2012). Immunogenicity evaluation of in silico Mycobacterium avium subsp paratuberculosis recombinant proteins that were upregulated under stress conditions. IVVDC

2012 , Queensland: N/A.

Gurung, R., Purdie (Williams), A., Begg, D.,

Whittington, R. (2012). In silico identification of epitopes in Mycobacterium avium subsp paratuberculosis proteins that were upregulated under stress conditions. Clinical and Vaccine

Immunology , 19(6), 855-864. <a href="http://dx.doi.org/10.1128/CVI.00114-12">

[More Information]</a>

Gurung, R., Purdie (Williams), A., Begg, D.,

Whittington, R. (2012). In silico screened

Mycobacterium avium subsp. paratuberculosis

(MAP) recombinant proteins upregulated under stress conditions are immunogenic in sheep.

Veterinary Immunology and Immunopathology ,

149(3-4), 186-196. <a href="http://dx.doi.org/10.1016/j.vetimm.2012.0

6.026">[More Information]</a>

Plain, K., de Silva, K., Earl, J., Begg, D., Purdie

(Williams), A., Whittington, R. (2012). The role of indoleamine 2,3-dioxygenase (IDO) and tryptophan catabolism in paratuberculosis disease progression. 11th International

Colloquium on Paratuberculosis , N/A: N/A.

Purdie (Williams), A., Begg, D., de Silva, K.,

Plain, K., Whittington, R. (2012). Transcriptomic analysis of sub clinical mycobacterium avium subsp.paratuberculosis infection in cattle. 11th

International Colloquium on Paratuberculosis ,

N/A: N/A.

Eppleston, J., Begg, D., Curran, G., Dhand, N.,

Watt, B., Whittington, R. (2012). Variability in

Publications for Douglas Begg environmental survival of ovine and bovine strains of MAP across climativ zones of NSW.

11th International Colloquium on

Paratuberculosis , N/A: N/A.

2011

Kawaji, S., Begg, D., Plain, K., Whittington, R.

(2011). A longitudinal study to evaluate the diagnostic potential of a direct faecal quantitative

PCR test for Johne's disease in sheep. Veterinary

Microbiology , 148(1), 35-44. <a href="http://dx.doi.org/10.1016/j.vetmic.2010.07

.022">[More Information]</a>

Zhong, L., Taylor, D., Begg, D., Whittington, R.

(2011). Biomarker discovery for ovine paratuberculosis (Johne's disease) by Proteomic serum profiling. Comparative Immunology,

Microbiology and Infectious Diseases: the international journal for medical and veterinary researchers and practitioners , 34(4), 315-326.

<a href="http://dx.doi.org/10.1016/j.cimid.2011.03.

001">[More Information]</a>

Purdie (Williams), A., Plain, K., Begg, D., de

Silva, K., Whittington, R. (2011). Candidate gene and genome-wide association studies of

Mycobacterium avium subsp. paratuberculosis infection in cattle and sheep: A review.

Comparative Immunology, Microbiology and

Infectious Diseases: the international journal for medical and veterinary researchers and practitioners , 34(3), 197-208. <a href="http://dx.doi.org/10.1016/j.cimid.2010.12.

003">[More Information]</a>

Bower (Goldsmith), K., Begg, D., Whittington,

R. (2011). Culture of Mycobacterium avium subspecies paratuberculosis (MAP) from blood and extra-intestinal tissues in experimentally infected sheep. Veterinary Microbiology ,

147(1-2), 127-132. <a href="http://dx.doi.org/10.1016/j.vetmic.2010.06

.016">[More Information]</a>

Begg, D., de Silva, K., Carter, N., Plain, K.,

Purdie (Williams), A., Whittington, R. (2011).

Does a Th1 over Th2 dominancy really exist in the early stages of Mycobacterium avium subspecies paratuberculosis infections?

Immunobiology , 216(7), 840-846. <a href="http://dx.doi.org/10.1016/j.imbio.2010.12.

004">[More Information]</a>

Plain, K., de Silva, K., Earl, J., Begg, D., Purdie

(Williams), A., Whittington, R. (2011).

Indoleamine 2,3-Dioxygenase, Tryptophan

Catabolism, and Mycobacterium avium subsp. paratuberculosis: a model for Chronic

Mycobacterial Infection. Infection and Immunity ,

79(9), 3821-3832. <a href="http://dx.doi.org/10.1128/IAI.05204-11">[

More Information]</a>

de Silva, K., Begg, D., Whittington, R. (2011).

The interleukin 10 response in ovine Johne's disease. Veterinary Immunology and

Immunopathology , 139(1), 10-16. <a href="http://dx.doi.org/10.1016/j.vetimm.2010.0

7.022">[More Information]</a>

2010

Begg, D., de Silva, K., Plain, K., Purdie

(Williams), A., Whittington, R. (2010). Does a

Th1 over Th2 dominance exist in the early stages of Mycobacterium avium subsp. paratuberculosis infections? 9th IVIS International Veterinary

Immunology Symposium , Amsterdam: Elsevier.

Begg, D., de Silva, K., Di Fiore, L., Taylor, D.,

Bower (Goldsmith), K., Zhong, L., Kawaji, S.,

Emery, D., Whittington, R. (2010). Experimental infection model for Johne's disease using a lyophilised, pure culture, seedstock of

Mycobacterium avium subspecies paratuberculosis. Veterinary Microbiology , 141,

301-311. <a href="http://dx.doi.org/10.1016/j.vetmic.2009.09

.007">[More Information]</a> de Silva, K., Begg, D., Plain, K., Purdie

(Williams), A., Kawaji, S., Whittington, R.

(2010). Immune correlates of protection and susceptibility to mycobacterial disease. 41st

Australasian Society for Immunology Annual

Meeting , N/A: N/A.

de Silva, K., Begg, D., Kawaji, S., Plain, K.,

Whittington, R. (2010). Immune profile and faecal shedding of Mycobacterium avium paratuberculosis vary with lesion severity in

Johne’s disease. 9th IVIS International

Veterinary Immunology Symposium , Amsterdam:

Elsevier.

Whittington, R., Begg, D., de Silva, K., Plain, K.,

Purdie (Williams), A. (2010). Immunological characteristics of paratuberculosis as a mycobacterial infection. 9th IVIS International

Veterinary Immunology Symposium , Amsterdam:

Elsevier.

Whittington, R., Begg, D., de Silva, K., Plain, K.,

Purdie (Williams), A. (2010). Mycobacterial infection – lessons from tuberculosis and paratuberculosis. 9th IVIS International

Veterinary Immunology Symposium , Amsterdam:

Elsevier.

Bower (Goldsmith), K., Begg, D., Whittington,

R. (2010). Optimisation of culture of

Mycobacterium avium subspecies paratuberculosis from blood samples. Journal of Microbiological Methods ,

80, 93-99. <a href="http://dx.doi.org/10.1016/j.mimet.2009.11.

005">[More Information]</a>

Bosward, K., Dhand, N., Begg, D., Thomson, P.,

Publications for Douglas Begg

Emery, D., Whittington, R. (2010). Optimization of a whole blood gamma interferon assay for the detection of sheep infected with mycobacterium avium subspecies paratuberculosis. Journal of Veterinary

Diagnostic Investigation , 22(2), 210-217.

Begg, D., Whittington, R. (2010).

Paratuberculosis in Sheep. In Marcel A. Behr,

Desmond M. Collins (Eds.), Paratuberculosis:

Organism, Disease, Control , (pp. 157-168).

Wallingford, UK: CABI Publishing.

Miller, Y., Collins, A., Emery, D., Begg, D.,

Smits, R., Harvey (Holyoake), P. (2010). Parity of the rearing dam can influence progeny innate immune responses. 21st International Pig

Veterinary Society Congress IPVS 2010 , Canada:

International Pig Veterinary Society.

Plain, K., de Silva, K., Earl, J., Begg, D., Purdie

(Williams), A., Whittington, R. (2010). Role of

IDO and tryptophan catabolism in chronic mycobacterial disease pathogenesis. 41st

Australasian Society for Immunology Annual

Meeting , N/A: N/A.

de Silva, K., Begg, D., Carter, N., Taylor, D., Di

Fiore, L., Whittington, R. (2010). The early lympocyte proliferation response in sheep exposed to Mycobacterium avium subsp. paratuberculosis compared to infection status.

Immunobiology , 215(1), 12-25. <a href="http://dx.doi.org/10.1016/j.imbio.2009.01.

014">[More Information]</a>

Plain, K., Purdie (Williams), A., Begg, D., de

Silva, K., Whittington, R. (2010). Toll-like receptor (TLR)6 and TLR1 differentiation in gene expression studies of Johne's disease.

Veterinary Immunology and Immunopathology ,

137(1-2), 142-148. <a href="http://dx.doi.org/10.1016/j.vetimm.2010.0

4.002">[More Information]</a>

2009

Bower (Goldsmith), K., Begg, D., Whittington,

R. (2009). Detection of Mycobacterium avium subspecies paratuberculosis (MAP) using culture from blood during early, subclinical and clinical stages of disease. 10th International Colloquium on Paratuberculosis , Minnesota: University of

Minnesota.

Begg, D., de Silva, K., Di Fiore, L., Taylor, D.,

Bower (Goldsmith), K., Zhong, L., Kawaji, S.,

Emery, D., Whittington, R. (2009). Development of an experimental infection model for Johne's disease using a lyophilised pure culture seedstock of Mycobacterium avium subspecies paratuberculosis. 10th International Colloquium on Paratuberculosis , Minnesota: University of

Minnesota.

Begg, D., Plain, K., Waldron, A., de Silva, K.,

Whittington, R. (2009). Development of an

Experimental Infection Model in Cattle using a

Low Passage Seed Stock of MAP. 10th

International Colloquium on Paratuberculosis ,

Minnesota: University of Minnesota.

Plain, K., Begg, D., Waldron, A., de Silva, K.,

Whittington, R. (2009). Development of an experimental infection protocol in cattle using a low passage cultured strain of MAP. 10th

International Colloquium on Paratuberculosis ,

USA: University of Minnesota.

Miller, Y., Collins, A., Smits, R., Begg, D.,

Emery, D., Harvey (Holyoake), P. (2009). Effect of dam parity on maternal transfer of specific

IgG into colostrum and milk following vaccination with tetanus toxoid. 12th

Australasian Pig Science Association Conference

APSA 2009 , Australia: Australasian Pig Science

Association.

Begg, D., de Silva, K., Bosward, K., Di Fiore, L.,

Taylor, D., Jungersen, G., Whittington, R.

(2009). Enzyme-linked immunospot: An alternative method for the detection of interferon gamma in Johne's disease. Journal of Veterinary

Diagnostic Investigation , 21(2), 187-196.

Zhong, L., Di Fiore, L., Taylor, D., Begg, D., de

Silva, K., Whittington, R. (2009). Identification of differentially expressed genes in ileum, intestinal lymph node and peripheral blood mononuclear cells of sheep infected with

Mycobacterium avium subsp. paratuberculosis using differential display polymerase chain reaction. Veterinary Immunology and

Immunopathology , 131(3-4), 177-189. <a href="http://dx.doi.org/10.1016/j.vetimm.2009.0

4.007">[More Information]</a> de Silva, K., Begg, D., Whittington, R. (2009).

The early IL-10 response in ovine Johne's disease. 10th International Colloquium on

Paratuberculosis , Minnesota: University of

Minnesota.

2008

Taylor, D., Zhong, L., Di Fiore, L., Begg, D., de

Silva, K., Whittington, R. (2008). Analysis of

Toll-like receptor gene expression in

Mycobacterium paratuberculosis infected sheep.

9th International Colloquium on

Paratuberculosis ICP 2007 , United States:

International Association for Paratuberculosis.

Browne, S., de Silva, K., Begg, D., Whittington,

R., Emery, D. (2008). Apoptosis of mononuclear cells in experimental and natural ovine Johne's disease. 9th International Colloquium on

Paratuberculosis ICP 2007 , United States:

International Association for Paratuberculosis.

Bower, K., Begg, D., Di Fiore, L., Taylor, D.,

Publications for Douglas Begg

Whittington, R. (2008). Culture of M. paratuberculosis from Blood. 9th International

Colloquium on Paratuberculosis ICP 2007 ,

United States: International Association for

Paratuberculosis.

Begg, D., Whittington, R. (2008). Experimental animal infection models for Johne's disease, an infectious enteropathy caused by Mycobacterium avium subsp. paratuberculosis. The Veterinary

Journal , 176, 129-145. <a href="http://dx.doi.org/10.1016/j.tvjl.2007.02.02

2">[More Information]</a>

Begg, D., Taylor, D., de Silva, K., Di Fiore, L.,

Whittington, R. (2008). Experimental infection of sheep with M.avium subspecies paratuberculosis: a brief review and introduction to an Australian ovine challenge model. 9th

International Colloquium on Paratuberculosis

ICP 2007 , United States: International

Association for Paratuberculosis.

de Silva, K., Begg, D., Taylor, D., Di Fiore, L.,

Whittington, R. (2008). Proliferation of lymphocyte subsets in experimental ovine

Johne's disease. 9th International Colloquium on

Paratuberculosis ICP 2007 , United States:

International Association for Paratuberculosis.

Plain, K., Begg, D., Whittington, R. (2008). Role of IDO in the response to Mycobacterium avium subspecies paratuberculosis infection.

Australasian Society for Immunology Conference

2008 , Australia: Australasian Society for

Immunology.

Begg, D., de Silva, K., Di Fiore, L., Taylor, D.,

Whittington, R. (2008). Seeing spots, developing an IFN-gamma ELISPOT assay to detect ovine

M. avium subspecies paratuberculosis infection.

9th International Colloquium on

Paratuberculosis ICP 2007 , United States:

International Association for Paratuberculosis.

Begg, D., de Silva, K., Whittington, R. (2008).

The IFN-g to antibody switch - does it really happen in Mycobacterium paratuberculosis infections? The 38th Australasian Society for

Immunology Annual Conference ASI 2008 ,

Australia: Australasian Society for Immunology.

Taylor, D., Zhong, L., Begg, D., de Silva, K.,

Whittington, R. (2008). Toll-like receptor genes are differentially expressed at the sites of infection during the progression of Johne's disease in outbred sheep. Veterinary Immunology and Immunopathology , 124, 132-151. <a href="http://dx.doi.org/10.1016/j.vetimm.2008.0

2.021">[More Information]</a>

2007

Hick, P., Gore, K., Whittington, R., Taylor, D.,

Begg, D., Schipp, G., Bosmans, J., Humphrey, J.,

Melville, L. (2007). Effect of incubation

Publications for Douglas Begg temperature on the permissivity of the SSN-1 cell line to Australian barramundi nervous necrosis virus (ABNNV). 3rd National FRDC

Aquatic Animal Health Scientific Conference

2007 , Australia: Fisheries Research and

Development Corporation.

2006

Gore, K., Hick, P., Begg, D., Taylor, D., Schipp,

G., Bosmans, J., Humphrey, J., Melville, L.,

Whittington, R. (2006). Effect of incubation temperature on the permissivity of the SSN-1 cell line to Australian barramundi nervous necrosis virus (ABNNV). 2006 Viral Nervous

Necrosis International Symposium , Hiroshima,

Japan: Japanese Society of Fish Pathology.

Gore, K., Hick, P., Begg, D., Taylor, D., Schipp,

G., Bosmans, J., Humphrey, J., Melville, J.,

Whittington, R. (2006). History of viral nervous necrosis outbreaks in farmed barramundi Lates calcarifer from the Northern Territory of

Australia. 2006 Viral Nervous Necrosis

International Symposium , Hiroshima, Japan:

Japanese Society of Fish Pathology.

Di Fiore, L., Taylor, D., de Silva, K., Bosward,

K., Begg, D., Emery, D., Whittington, R. (2006).

Identificaiton of differentially expressed genes in uninfected and Mycobacterium paratuberculosis

(M.ptb. ) infected sheep. The 8th International

Colloquium on Paratuberculosis , N/A: N/A.

Di Fiore, L., Taylor, D., de Silva, K., Bosward,

K., Begg, D., Emery, D., Whittington, R. (2006).

Identification of differentially expressed genes in uninfected and Mycobacterium paratuberculosis

(M. ptb.) infected sheep. 8th International

Colloquium on Paratuberculosis ICP 2005 ,

United States: International Association for

Paratuberculosis.

Begg, D., Griffin, F. (2006). Immune parameters and vaccine efficacy in Mycobacterium avium subspecies paratuberculosis experimentally infected sheep. 8th International Colloquium on

Paratuberculosis ICP 2005 , United States:

International Association for Paratuberculosis.

Bosward, K., Begg, D., de Silva, K., Di Fiore, L.,

Taylor, D., Emery, D., Whittington, R. (2006).

Optimisation of the interferon-gamma assay to maximise responses to M. ptb. antigen in sheep.

8th International Colloquium on

Paratuberculosis ICP 2005 , United States:

International Association for Paratuberculosis.

Hick, P., Gore, K., Taylor, D., Begg, D., Schipp,

G., Bosmans, J., Humphrey, J., Melville, L.,

Whittington, R. (2006). Permissivity of the

SSN-1 cell line to Lates calcarifer nervous necrosis virus. 2006 Viral Nervous Necrosis

International Symposium , Hiroshima, Japan:

Japanese Society of Fish Pathology.

Begg, D., de Silva, K., Di Fiore, L., Taylor, D.,

Whittington, R. (2006). Seeing spots, using the

ELISPOT assay to detect M. avium subspecies paratuberculosis infection in sheep. Australasian

Society for Immunology Conference 2006 ,

Australia: Australasian Society for Immunology.

2005

Bower (Goldsmith), K., Begg, D., Di Fiore, L.,

Whittington, R. (2005). Detection of

Mycobacteria from blood. MLA OJD Harvest

Year Conference , North Sydney, N.S.W: Meat &

Livestock Australia Ltd.

de Silva, K., Begg, D., Di Fiore, L., Taylor, D.,

Emery, D., Whittington, R. (2005). Early cellular responses in ovine Johne's disease. MLA OJD

Harvest Year Conference , North Sydney, N.S.W:

Meat & Livestock Australia Ltd.

Begg, D., Bosward, K., de Silva, K., Di Fiore, L.,

Taylor, D., Whittington, R. (2005). ELISPOT - new methods for detecting IFN-y. MLA OJD

Harvest Year Conference , North Sydney, N.S.W:

Meat & Livestock Australia Ltd.

Begg, D., O'Brien, R., Mackintosh, C., Griffin,

F. (2005). Experimental infection model for

Johne's disease in sheep. Infection and Immunity ,

73(9), 5603-5611.

Bosward, K., Begg, D., de Silva, K., Di Fiore, L.,

Taylor, D., Whittington, R. (2005). Manipulation of the Interferon - gamma assay to maximise responses to M. ptb antigen in sheep. MLA OJD

Harvest Year Conference , North Sydney, N.S.W:

Meat & Livestock Australia Ltd.

Taylor, D., Gumber, S., de Silva, K., Bower

(Goldsmith), K., Di Fiore, L., Begg, D.,

Whittington, R. (2005). Molecular approaches to studying the host-parasite interaction. MLA OJD

Harvest Year Conference , North Sydney, N.S.W:

Meat & Livestock Australia Ltd.

Begg, D., Griffin, F. (2005). Vaccination of sheep against M. paratuberculosis: Immune parameters and protective efficacy. Vaccine ,

23(42), 4999-5008.

2004

Begg, D., Kemp, R., Griffin, F. (2004). Normal levels of immunocompetence in possums

(Trichosurus vulpecula) exposed to different laboratory housing conditions post capture.

Immunology and Cell Biology , 82(3), 253-256.

2003

Begg, D., Crosbie, P., Griffin, F. (2003). Ovine

Johne's disease: Comparative immunological responses in peripheral blood and gut associated lymphoid tissue. Australasian Society for

Immunology Conference 2003 , Australia:

Australasian Society for Immunology.

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