Publications for Douglas Begg
2016
Swift, B., Huxley, J., Plain, K., Begg, D., de
Silva, K., Purdie (Williams), A., Whittington, R.,
Rees, C. (2016). Evaluation of the limitations and methods to improve rapid phage-based detection of viable Mycobacterium avium subsp. paratuberculosis in the blood of experimentally infected cattle. BMC Veterinary
Research , 12(115). <a href="http://dx.doi.org/10.1186/s12917-016-072
8-2">[More Information]</a>
Swift, B., Huxley, J., Plain, K., Begg, D., de
Silva, K., Purdie (Williams), A., Whittington, R.,
Rees, C. (2016). Evaluation of the limitations and methods to improve rapid phage-based detection of viable Mycobacterium avium subsp. paratuberculosis in the blood of experimentally infected cattle. BMC Veterinary
Research , 12, 115. <a href="http://dx.doi.org/10.1186/s12917-016-072
8-2">[More Information]</a>
2015 de Silva, K., Plain, K., Begg, D., Purdie
(Williams), A., Whittington, R. (2015). CD4+
T-cells, T-cells and B-cells are associated with lack of vaccine protection in Mycobacterium avium subspecies paratuberculosis infection.
Vaccine , 33, 149-155. <a href="http://dx.doi.org/10.1016/j.vaccine.2014.1
0.082">[More Information]</a>
Plain, K., Waldron, A., Begg, D., de Silva, K.,
Purdie (Williams), A., Whittington, R. (2015).
Efficient, validated method for the detection of mycobacterial growth in liquid culture media using bead-beating, magnetic particle nucleic acid isolation and quantitative PCR. Journal of
Clinical Microbiology , 53(4), 1121-1128. <a href="http://dx.doi.org/10.1128/JCM.03521-14"
>[More Information]</a>
Gulliver, E., Plain, K., Begg, D., Whittington, R.
(2015). Histopathological Characterization of
Cutaneous Delayed-type Hypersensitivity and
Correlations with Intestinal Pathology and
Systemic Immune Responses in Sheep with
Paratuberculosis. Journal of Comparative
Pathology , 153, 67-80. <a href="http://dx.doi.org/10.1016/j.jcpa.2015.05.00
5">[More Information]</a>
Thirunavukkarasu, S., de Silva, K., Begg, D.,
Whittington, R., Plain, K. (2015). Macrophage polarization in cattle experimentally exposed to
Mycobacterium avium subsp. paratuberculosis.
Pathogens and Disease , 73(9), 1-9. <a
Publications for Douglas Begg href="http://dx.doi.org/10.1093/femspd/ftv085">
[More Information]</a>
Begg, D., de Silva, K., Plain, K., Purdie
(Williams), A., Dhand, N., Whittington, R.
(2015). Specific faecal antibody responses in sheep infected with Mycobacterium avium subspecies paratuberculosis. Veterinary
Immunology and Immunopathology , 166(3-4),
125-131. <a href="http://dx.doi.org/10.1016/j.vetimm.2015.0
6.011">[More Information]</a>
Johansen, M., Purdie (Williams), A., de Silva,
K., Plain, K., Begg, D., Whittington, R. (2015).
The role of intracellular cholesterol within macrophages exposed to Mycabacterium Avium subsp. paratuberculosis. 43rd Annual Scientific
Meeting of the Australian Society for
Microbiology , N/A: N/A.
2014
Whittington, R., Whittington, A., Waldron, A.,
Begg, D., de Silva, K., Purdie (Williams), A.,
Plain, K. (2014). A liquid medium (M7H9C) for routine culture of Mycobacterium Avium Subsp
Paratuberculosis to replace Bactec 12. 12th
International Colloquium on Paratuberculosis ,
Italy: N/A.
Whittington, R., Whittington, A., Waldron, A.,
Begg, D., de Silva, K., Purdie (Williams), A.,
Plain, K. (2014). A liquid medium (M7H9C) for routine culture of Mycobacterium Avium Subsp.
Paratuberculosis to replace Bactec 12. 12th
International Colloquium on Paratuberculosis ,
Italy: N/A.
Plain, K., Marsh, I., Begg, D., Purdie (Williams),
A., de Silva, K., Whittington, R. (2014). A new molecular diagnostic test for Johne's disease; from lab to national uptake. 12th International
Colloquium on Paratuberculosis , Italy: N/A.
Gurung, R., Begg, D., Purdie (Williams), A.,
Whittington, R. (2014). Antigenicity in sheep of synthetic peptides derived from stress-regulated
Mycobacterium avium subsp. paratuberculosis proteins and comparison with recombinant protein and complex native antigens. Veterinary
Immunology and Immunopathology , 158(1-2),
46-52. <a href="http://dx.doi.org/10.1016/j.vetimm.2013.0
5.016">[More Information]</a>
Gurung, R., Purdie (Williams), A., Whittington,
R., Begg, D. (2014). Cellular and humoral immune responses in sheep vaccinated with candidate antigens MAP2698c and MAP3567 from Mycobacterium avium subspecies paratuberculosis. Frontiers in Cellular and
Infection Microbiology , 14(93), 1-8. <a href="http://dx.doi.org/10.3389/fcimb.00093">[
More Information]</a>
Purdie (Williams), A., Begg, D., de Silva, K.,
Plain, K., Whittington, R. (2014). Consistent gene expression panels identified at early time points that predict clinical outcomes of JD in
Sheep. 12th International Colloquium on
Paratuberculosis , Italy: N/A.
Purdie (Williams), A., Begg, D., de Silva, K.,
Plain, K., Whittington, R. (2014). Consistent gene expression panels identified at early time points that predict clinical outcomes of JD in sheep. 12th International Colloquium on
Paratuberculosis , Italy: N/A.
Eppleston, J., Begg, D., Dhand, N., Watt, B.,
Whittington, R. (2014). Environmental Survival of mycobacterium avium subsp. paratuberculosis in Different Climatic Zones of Eastern Australia.
Applied and Environmental Microbiology , 80(8),
2337-2342. <a href="http://dx.doi.org/10.1128/AEM.03630-13"
>[More Information]</a>
Thirunavukkarasu, S., Plain, K., de Silva, K.,
Begg, D., Whittington, R., Purdie (Williams), A.
(2014). Expression of genes associated with cholesterol and lipid metabolism identified as a novel pathway in the early pathogenesis of
Mycobacterium avium subspecies paratuberculosis - infection in cattle. Veterinary
Immunology and Immunopathology , 160(3-4),
147-157. <a href="http://dx.doi.org/10.1016/j.vetimm.2014.0
4.002">[More Information]</a>
Plain, K., Marsh, I., Waldron, A., Galea, F.,
Whittington, A., Saunders, V., Begg, D., de
Silva, K., Purdie (Williams), A., Whittington, R.
(2014). High-Throughput Direct Faecal PCR
Assay to detection of Mycobacterium avium subspecies paratuberculosis in sheep and cattle.
Journal of Clinical Microbiology , 52(3),
745-757. <a href="http://dx.doi.org/10.1128/JCM.03233-13"
>[More Information]</a>
Gurung, R., Begg, D., Purdie (Williams), A.,
Bach, H., Whittington, R. (2014).
Immunoreactivity of protein tyrosine phosphatase A (PtpA) in sera from sheep infected with Mycobacterium avium subspecies paratuberculosis. Veterinary Immunology and
Immunopathology , 160, 129-132. <a href="http://dx.doi.org/10.1016/j.vetimm.2014.0
3.013">[More Information]</a>
Begg, D., Plain, K., de Silva, K., Purdie
(Williams), A., Whittington, R. (2014). John's disease; a mycobacterial infection of ruminants.
The Australian Society for Microbiology , N/A:
N/A.
Begg, D. (2014). Johne’s disease; a
Mycobacterial infection of Ruminants. National
Institute for Mathematical and Biological
Publications for Douglas Begg
Synthesis seminar series , N/A: N/A.
Gurung, R., Begg, D., Purdie (Williams), A., de
Silva, K., Bannantine, J., Whittington, R. (2014).
Lymphoproliferative and Gamma Interferon responses to stress-regulated Mycobacterium avium subspecies paratuberculosis recombinant proteins. Clinical and Vaccine Immunology ,
21(6), 831-837. <a href="http://dx.doi.org/10.1128/CVI.00775-13">
[More Information]</a>
Gurung, R., Purdie (Williams), A., Begg, D., de
Silva, K., Plain, K., Whittington, R. (2014).
Mycobacterium Avium subspecies
Paratuberculosis stressome and diagnostic significance: A review and Meta-analysis. 12th
International Colloquium on Paratuberculosis ,
Italy: N/A.
Begg, D., Plain, K., de Silva, K., Purdie
(Williams), A., Whittington, R. (2014).
Production of Mucosal antibody in response to
Paratuberculosis infection. 12th International
Colloquium on Paratuberculosis , Italy: N/A.
de Silva, K., Purdie (Williams), A., Plain, K.,
Begg, D., Whittington, R. (2014). Understanding vaccine failure I relation to immune parameters in map infection. 12th International Colloquium on Paratuberculosis , Italy: N/A.
de Silva, K., Purdie (Williams), A., Plain, K.,
Begg, D., Whittington, R. (2014). Understanding vaccine failure in relation to immune parameters in map infection. 12th International Colloquium on Paratuberculosis , Italy: N/A.
2013
Gurung, R., Begg, D., Purdie (Williams), A.,
Bannantine, J., Whittington, R. (2013).
Antigenicity of Recombinant Maltose Binding
Protein-Mycobacterium avium subsp.
Paratuberculosis Fusion Proteins with and without Factor Xa Cleaving. Clinical and
Vaccine Immunology , 20(12), 1817-1826. <a href="http://dx.doi.org/10.1128/CVI.00596-13">
[More Information]</a> de Silva, K., Browne, S., Begg, D., Whittington,
R., Emery, D. (2013). Apoptosis of lymph node and peripheral blood cells in ovine Johne's disease. Veterinary Immunology and
Immunopathology , 156(1-2), 82-90. <a href="http://dx.doi.org/10.1016/j.vetimm.2013.0
8.001">[More Information]</a> de Silva, K., Begg, D., Plain, K., Purdie
(Williams), A., Kawaji, S., Dhand, N.,
Whittington, R. (2013). Can early host responses to mycobacterial infection predict eventual disease outcomes? Preventive Veterinary
Medicine , 112, 203-212. <a href="http://dx.doi.org/10.1016/j.prevetmed.201
3.08.006">[More Information]</a>
de Silva, K., Begg, D., Purdie (Williams), A.,
Plain, K., Whittington, R. (2013). Comparison
Of The Host Immune Response To Gudair®
Vaccination And Map Exposure. International
Veterinary Immunology Syposium .
Whittington, R., Whittington, A., Waldron, A.,
Begg, D., de Silva, K., Purdie (Williams), A.,
Plain, K. (2013). Development and validation of a liquid medium (M7H9C) for routine culture of
Mycobacterium avium subsp. paratuberculosis to replace modified Bactec 12B medium. Journal of
Clinical Microbiology , 51(12), 3993-4000. <a href="http://dx.doi.org/10.1128/JCM.01373-13"
>[More Information]</a>
Begg, D., Whittington, R. (2013). Johne’s disease in sheep. 8th International Sheep
Veterinary Congress , Rotorua, New Zealand:
New Zealand Veterinary Association Inc.
Miller, Y., Collins, A., Emery, D., Begg, D.,
Smits, R., Holyoake, P. (2013). Piglet performance and immunity is determined by the parity of both the birth dam and the rearing dam.
Animal Production Science , 53(1), 46-51. <a href="http://dx.doi.org/10.1071/AN12063">[Mo re Information]</a>
Bower (Goldsmith), K., Begg, D., Whittington,
R. (2013). Tissue localisation of Mycobacterium avium subspecies paratuberculosis following artificially induced intracellular and naked bacteraemia. Veterinary Microbiology , 162(1),
112-118. <a href="http://dx.doi.org/10.1016/j.vetmic.2012.03
.007">[More Information]</a>
2012
Plain, K., Marsh, B., Begg, D., Galea, F.,
Waldron, A., Whittington, A., Whittington, R.
(2012). A new high-throughput direct faecal
PCR test for Johnes diesease. IVVDC 2012 ,
Queensland: N/A.
Plain, K., Marsh, I., Begg, D., Galea, F.,
Waldron, A., Whittington, A., Whittington, R.
(2012). A new high-throughput direct faecal
PCR test for Johne’s disease. 6th International
Veterinary Vaccines and Diagnostics
Conference , N/A: N/A.
Whittington, R., Begg, D., de Silva, K., Plain, K.,
Purdie (Williams), A. (2012). Comparative immunological and microbiological aspects of paratuberculosis as a model mycobacterial infection. Veterinary Immunology and
Immunopathology , 148(1-2), 29-47. <a href="http://dx.doi.org/10.1016/j.vetimm.2011.0
3.003">[More Information]</a>
Purdie (Williams), A., Begg, D., de Silva, K.,
Plain, K., Whittington, R. (2012). Differential gene expression changes associated with sub-clinical Mycobacterium avium subspecies
Publications for Douglas Begg paratuberculosis infection in cattle: a transcriptomic study. Immunology 2012 , usa:
N/A.
de Silva, K., Begg, D., Plain, K., Purdie
(Williams), A., Kawaji, S., Dhand, N.,
Whittington, R. (2012). Early biomarkers of resistance and susceptibility to mycobacterial disease. Immunology 2012 , usa: N/A.
Plain, K., Begg, D., de Silva, K., Purdie
(Williams), A., Whittington, R. (2012).
Enhancement of the interferon gamma assay to detect paratuberculosis using interleukin-7 and interleukin-12 potentiation. Veterinary
Immunology and Immunopathology , 149(1-2),
28-37. <a href="http://dx.doi.org/10.1016/j.vetimm.2012.0
5.023">[More Information]</a>
Eppleston, J., Begg, D., Curran, G., Dhand, N.,
Watt, B., Whittington, R. (2012). Envoronmental survival of MAP across New South Wales. 94th
District veterinarian's Conference , Wollongong:
District veterinarian's association.
Purdie (Williams), A., Plain, K., Begg, D., de
Silva, K., Whittington, R. (2012). Expression of genes associated with the antigen presentation and processing pathway are consistently regulated in early Mycobacterium avium subsp. paratuberculosis infection. Comparative
Immunology, Microbiology and Infectious
Diseases: the international journal for medical and veterinary researchers and practitioners ,
35(2), 151-162. <a href="http://dx.doi.org/10.1016/j.cimid.2011.12.
007">[More Information]</a>
Begg, D., Plain, K., de Silva, K., Purdie
(Williams), A., Whittington, R. (2012).
Extension of the storage time of blood in interferon gamma assays to diagnose paratuberculosis: combination of IL-7 and IL-12 stimulation. 6th International Veterinary
Vaccines and Diagnostics Conference , N/A:
N/A.
Begg, D., Plain, K., de Silva, K., Purdie
(Williams), A., Whittington, R. (2012).
Extension of the storage time of blood in interferon gamma assays to disgnose paratuberculosis: combination of II-7 and II-12 stimulation. 4th European Veterinary
Immunology Workshop (EVIW) , N/A: N/A.
Begg, D., Plain, K., de Silva, K., Purdie
(Williams), A., Whittington, R. (2012).
Extension of the storgage time of blood in interferon gamma assay to diagnose paratuberculosis: reporting guidelines. 11th
International Colloquium on Paratuberculosis ,
N/A: N/A.
de Silva, K., Begg, D., Plain, K., Purdie
(Williams), A., Kawaji, S., Whittington, R.
(2012). Immune profiles and faecal shedding of
Mycobacterium avium paratuberculosis indicate eventual severity of Johne's Disease. 11th
International Colloquium on Paratuberculosis ,
N/A: N/A.
Dukkipati, V., Ridler, A., Buddle, B.,
Hedgespeth, B., Begg, D., Whittington, R.,
Murray, A. (2012). Immune response profiles of lambs infected with a lyophilised pure culture seed-stock of mycobacterium avium subspecies paratuberculosis. 11th International Colloquium on Paratuberculosis , N/A: N/A.
Gurung, R., Purdie (Williams), A., Begg, D.,
Whittington, R. (2012). Immunogenicity evaluation of in silico identified MAP recombinant proteins that were upregulated under stress conditions. 11th International
Colloquium on Paratuberculosis , N/A: N/A.
Gurung, R., Begg, D., Purdie (Williams), A.,
Whittington, R. (2012). Immunogenicity evaluation of in silico Mycobacterium avium subsp paratuberculosis recombinant proteins that were upregulated under stress conditions. IVVDC
2012 , Queensland: N/A.
Gurung, R., Purdie (Williams), A., Begg, D.,
Whittington, R. (2012). In silico identification of epitopes in Mycobacterium avium subsp paratuberculosis proteins that were upregulated under stress conditions. Clinical and Vaccine
Immunology , 19(6), 855-864. <a href="http://dx.doi.org/10.1128/CVI.00114-12">
[More Information]</a>
Gurung, R., Purdie (Williams), A., Begg, D.,
Whittington, R. (2012). In silico screened
Mycobacterium avium subsp. paratuberculosis
(MAP) recombinant proteins upregulated under stress conditions are immunogenic in sheep.
Veterinary Immunology and Immunopathology ,
149(3-4), 186-196. <a href="http://dx.doi.org/10.1016/j.vetimm.2012.0
6.026">[More Information]</a>
Plain, K., de Silva, K., Earl, J., Begg, D., Purdie
(Williams), A., Whittington, R. (2012). The role of indoleamine 2,3-dioxygenase (IDO) and tryptophan catabolism in paratuberculosis disease progression. 11th International
Colloquium on Paratuberculosis , N/A: N/A.
Purdie (Williams), A., Begg, D., de Silva, K.,
Plain, K., Whittington, R. (2012). Transcriptomic analysis of sub clinical mycobacterium avium subsp.paratuberculosis infection in cattle. 11th
International Colloquium on Paratuberculosis ,
N/A: N/A.
Eppleston, J., Begg, D., Curran, G., Dhand, N.,
Watt, B., Whittington, R. (2012). Variability in
Publications for Douglas Begg environmental survival of ovine and bovine strains of MAP across climativ zones of NSW.
11th International Colloquium on
Paratuberculosis , N/A: N/A.
2011
Kawaji, S., Begg, D., Plain, K., Whittington, R.
(2011). A longitudinal study to evaluate the diagnostic potential of a direct faecal quantitative
PCR test for Johne's disease in sheep. Veterinary
Microbiology , 148(1), 35-44. <a href="http://dx.doi.org/10.1016/j.vetmic.2010.07
.022">[More Information]</a>
Zhong, L., Taylor, D., Begg, D., Whittington, R.
(2011). Biomarker discovery for ovine paratuberculosis (Johne's disease) by Proteomic serum profiling. Comparative Immunology,
Microbiology and Infectious Diseases: the international journal for medical and veterinary researchers and practitioners , 34(4), 315-326.
<a href="http://dx.doi.org/10.1016/j.cimid.2011.03.
001">[More Information]</a>
Purdie (Williams), A., Plain, K., Begg, D., de
Silva, K., Whittington, R. (2011). Candidate gene and genome-wide association studies of
Mycobacterium avium subsp. paratuberculosis infection in cattle and sheep: A review.
Comparative Immunology, Microbiology and
Infectious Diseases: the international journal for medical and veterinary researchers and practitioners , 34(3), 197-208. <a href="http://dx.doi.org/10.1016/j.cimid.2010.12.
003">[More Information]</a>
Bower (Goldsmith), K., Begg, D., Whittington,
R. (2011). Culture of Mycobacterium avium subspecies paratuberculosis (MAP) from blood and extra-intestinal tissues in experimentally infected sheep. Veterinary Microbiology ,
147(1-2), 127-132. <a href="http://dx.doi.org/10.1016/j.vetmic.2010.06
.016">[More Information]</a>
Begg, D., de Silva, K., Carter, N., Plain, K.,
Purdie (Williams), A., Whittington, R. (2011).
Does a Th1 over Th2 dominancy really exist in the early stages of Mycobacterium avium subspecies paratuberculosis infections?
Immunobiology , 216(7), 840-846. <a href="http://dx.doi.org/10.1016/j.imbio.2010.12.
004">[More Information]</a>
Plain, K., de Silva, K., Earl, J., Begg, D., Purdie
(Williams), A., Whittington, R. (2011).
Indoleamine 2,3-Dioxygenase, Tryptophan
Catabolism, and Mycobacterium avium subsp. paratuberculosis: a model for Chronic
Mycobacterial Infection. Infection and Immunity ,
79(9), 3821-3832. <a href="http://dx.doi.org/10.1128/IAI.05204-11">[
More Information]</a>
de Silva, K., Begg, D., Whittington, R. (2011).
The interleukin 10 response in ovine Johne's disease. Veterinary Immunology and
Immunopathology , 139(1), 10-16. <a href="http://dx.doi.org/10.1016/j.vetimm.2010.0
7.022">[More Information]</a>
2010
Begg, D., de Silva, K., Plain, K., Purdie
(Williams), A., Whittington, R. (2010). Does a
Th1 over Th2 dominance exist in the early stages of Mycobacterium avium subsp. paratuberculosis infections? 9th IVIS International Veterinary
Immunology Symposium , Amsterdam: Elsevier.
Begg, D., de Silva, K., Di Fiore, L., Taylor, D.,
Bower (Goldsmith), K., Zhong, L., Kawaji, S.,
Emery, D., Whittington, R. (2010). Experimental infection model for Johne's disease using a lyophilised, pure culture, seedstock of
Mycobacterium avium subspecies paratuberculosis. Veterinary Microbiology , 141,
301-311. <a href="http://dx.doi.org/10.1016/j.vetmic.2009.09
.007">[More Information]</a> de Silva, K., Begg, D., Plain, K., Purdie
(Williams), A., Kawaji, S., Whittington, R.
(2010). Immune correlates of protection and susceptibility to mycobacterial disease. 41st
Australasian Society for Immunology Annual
Meeting , N/A: N/A.
de Silva, K., Begg, D., Kawaji, S., Plain, K.,
Whittington, R. (2010). Immune profile and faecal shedding of Mycobacterium avium paratuberculosis vary with lesion severity in
Johne’s disease. 9th IVIS International
Veterinary Immunology Symposium , Amsterdam:
Elsevier.
Whittington, R., Begg, D., de Silva, K., Plain, K.,
Purdie (Williams), A. (2010). Immunological characteristics of paratuberculosis as a mycobacterial infection. 9th IVIS International
Veterinary Immunology Symposium , Amsterdam:
Elsevier.
Whittington, R., Begg, D., de Silva, K., Plain, K.,
Purdie (Williams), A. (2010). Mycobacterial infection – lessons from tuberculosis and paratuberculosis. 9th IVIS International
Veterinary Immunology Symposium , Amsterdam:
Elsevier.
Bower (Goldsmith), K., Begg, D., Whittington,
R. (2010). Optimisation of culture of
Mycobacterium avium subspecies paratuberculosis from blood samples. Journal of Microbiological Methods ,
80, 93-99. <a href="http://dx.doi.org/10.1016/j.mimet.2009.11.
005">[More Information]</a>
Bosward, K., Dhand, N., Begg, D., Thomson, P.,
Publications for Douglas Begg
Emery, D., Whittington, R. (2010). Optimization of a whole blood gamma interferon assay for the detection of sheep infected with mycobacterium avium subspecies paratuberculosis. Journal of Veterinary
Diagnostic Investigation , 22(2), 210-217.
Begg, D., Whittington, R. (2010).
Paratuberculosis in Sheep. In Marcel A. Behr,
Desmond M. Collins (Eds.), Paratuberculosis:
Organism, Disease, Control , (pp. 157-168).
Wallingford, UK: CABI Publishing.
Miller, Y., Collins, A., Emery, D., Begg, D.,
Smits, R., Harvey (Holyoake), P. (2010). Parity of the rearing dam can influence progeny innate immune responses. 21st International Pig
Veterinary Society Congress IPVS 2010 , Canada:
International Pig Veterinary Society.
Plain, K., de Silva, K., Earl, J., Begg, D., Purdie
(Williams), A., Whittington, R. (2010). Role of
IDO and tryptophan catabolism in chronic mycobacterial disease pathogenesis. 41st
Australasian Society for Immunology Annual
Meeting , N/A: N/A.
de Silva, K., Begg, D., Carter, N., Taylor, D., Di
Fiore, L., Whittington, R. (2010). The early lympocyte proliferation response in sheep exposed to Mycobacterium avium subsp. paratuberculosis compared to infection status.
Immunobiology , 215(1), 12-25. <a href="http://dx.doi.org/10.1016/j.imbio.2009.01.
014">[More Information]</a>
Plain, K., Purdie (Williams), A., Begg, D., de
Silva, K., Whittington, R. (2010). Toll-like receptor (TLR)6 and TLR1 differentiation in gene expression studies of Johne's disease.
Veterinary Immunology and Immunopathology ,
137(1-2), 142-148. <a href="http://dx.doi.org/10.1016/j.vetimm.2010.0
4.002">[More Information]</a>
2009
Bower (Goldsmith), K., Begg, D., Whittington,
R. (2009). Detection of Mycobacterium avium subspecies paratuberculosis (MAP) using culture from blood during early, subclinical and clinical stages of disease. 10th International Colloquium on Paratuberculosis , Minnesota: University of
Minnesota.
Begg, D., de Silva, K., Di Fiore, L., Taylor, D.,
Bower (Goldsmith), K., Zhong, L., Kawaji, S.,
Emery, D., Whittington, R. (2009). Development of an experimental infection model for Johne's disease using a lyophilised pure culture seedstock of Mycobacterium avium subspecies paratuberculosis. 10th International Colloquium on Paratuberculosis , Minnesota: University of
Minnesota.
Begg, D., Plain, K., Waldron, A., de Silva, K.,
Whittington, R. (2009). Development of an
Experimental Infection Model in Cattle using a
Low Passage Seed Stock of MAP. 10th
International Colloquium on Paratuberculosis ,
Minnesota: University of Minnesota.
Plain, K., Begg, D., Waldron, A., de Silva, K.,
Whittington, R. (2009). Development of an experimental infection protocol in cattle using a low passage cultured strain of MAP. 10th
International Colloquium on Paratuberculosis ,
USA: University of Minnesota.
Miller, Y., Collins, A., Smits, R., Begg, D.,
Emery, D., Harvey (Holyoake), P. (2009). Effect of dam parity on maternal transfer of specific
IgG into colostrum and milk following vaccination with tetanus toxoid. 12th
Australasian Pig Science Association Conference
APSA 2009 , Australia: Australasian Pig Science
Association.
Begg, D., de Silva, K., Bosward, K., Di Fiore, L.,
Taylor, D., Jungersen, G., Whittington, R.
(2009). Enzyme-linked immunospot: An alternative method for the detection of interferon gamma in Johne's disease. Journal of Veterinary
Diagnostic Investigation , 21(2), 187-196.
Zhong, L., Di Fiore, L., Taylor, D., Begg, D., de
Silva, K., Whittington, R. (2009). Identification of differentially expressed genes in ileum, intestinal lymph node and peripheral blood mononuclear cells of sheep infected with
Mycobacterium avium subsp. paratuberculosis using differential display polymerase chain reaction. Veterinary Immunology and
Immunopathology , 131(3-4), 177-189. <a href="http://dx.doi.org/10.1016/j.vetimm.2009.0
4.007">[More Information]</a> de Silva, K., Begg, D., Whittington, R. (2009).
The early IL-10 response in ovine Johne's disease. 10th International Colloquium on
Paratuberculosis , Minnesota: University of
Minnesota.
2008
Taylor, D., Zhong, L., Di Fiore, L., Begg, D., de
Silva, K., Whittington, R. (2008). Analysis of
Toll-like receptor gene expression in
Mycobacterium paratuberculosis infected sheep.
9th International Colloquium on
Paratuberculosis ICP 2007 , United States:
International Association for Paratuberculosis.
Browne, S., de Silva, K., Begg, D., Whittington,
R., Emery, D. (2008). Apoptosis of mononuclear cells in experimental and natural ovine Johne's disease. 9th International Colloquium on
Paratuberculosis ICP 2007 , United States:
International Association for Paratuberculosis.
Bower, K., Begg, D., Di Fiore, L., Taylor, D.,
Publications for Douglas Begg
Whittington, R. (2008). Culture of M. paratuberculosis from Blood. 9th International
Colloquium on Paratuberculosis ICP 2007 ,
United States: International Association for
Paratuberculosis.
Begg, D., Whittington, R. (2008). Experimental animal infection models for Johne's disease, an infectious enteropathy caused by Mycobacterium avium subsp. paratuberculosis. The Veterinary
Journal , 176, 129-145. <a href="http://dx.doi.org/10.1016/j.tvjl.2007.02.02
2">[More Information]</a>
Begg, D., Taylor, D., de Silva, K., Di Fiore, L.,
Whittington, R. (2008). Experimental infection of sheep with M.avium subspecies paratuberculosis: a brief review and introduction to an Australian ovine challenge model. 9th
International Colloquium on Paratuberculosis
ICP 2007 , United States: International
Association for Paratuberculosis.
de Silva, K., Begg, D., Taylor, D., Di Fiore, L.,
Whittington, R. (2008). Proliferation of lymphocyte subsets in experimental ovine
Johne's disease. 9th International Colloquium on
Paratuberculosis ICP 2007 , United States:
International Association for Paratuberculosis.
Plain, K., Begg, D., Whittington, R. (2008). Role of IDO in the response to Mycobacterium avium subspecies paratuberculosis infection.
Australasian Society for Immunology Conference
2008 , Australia: Australasian Society for
Immunology.
Begg, D., de Silva, K., Di Fiore, L., Taylor, D.,
Whittington, R. (2008). Seeing spots, developing an IFN-gamma ELISPOT assay to detect ovine
M. avium subspecies paratuberculosis infection.
9th International Colloquium on
Paratuberculosis ICP 2007 , United States:
International Association for Paratuberculosis.
Begg, D., de Silva, K., Whittington, R. (2008).
The IFN-g to antibody switch - does it really happen in Mycobacterium paratuberculosis infections? The 38th Australasian Society for
Immunology Annual Conference ASI 2008 ,
Australia: Australasian Society for Immunology.
Taylor, D., Zhong, L., Begg, D., de Silva, K.,
Whittington, R. (2008). Toll-like receptor genes are differentially expressed at the sites of infection during the progression of Johne's disease in outbred sheep. Veterinary Immunology and Immunopathology , 124, 132-151. <a href="http://dx.doi.org/10.1016/j.vetimm.2008.0
2.021">[More Information]</a>
2007
Hick, P., Gore, K., Whittington, R., Taylor, D.,
Begg, D., Schipp, G., Bosmans, J., Humphrey, J.,
Melville, L. (2007). Effect of incubation
Publications for Douglas Begg temperature on the permissivity of the SSN-1 cell line to Australian barramundi nervous necrosis virus (ABNNV). 3rd National FRDC
Aquatic Animal Health Scientific Conference
2007 , Australia: Fisheries Research and
Development Corporation.
2006
Gore, K., Hick, P., Begg, D., Taylor, D., Schipp,
G., Bosmans, J., Humphrey, J., Melville, L.,
Whittington, R. (2006). Effect of incubation temperature on the permissivity of the SSN-1 cell line to Australian barramundi nervous necrosis virus (ABNNV). 2006 Viral Nervous
Necrosis International Symposium , Hiroshima,
Japan: Japanese Society of Fish Pathology.
Gore, K., Hick, P., Begg, D., Taylor, D., Schipp,
G., Bosmans, J., Humphrey, J., Melville, J.,
Whittington, R. (2006). History of viral nervous necrosis outbreaks in farmed barramundi Lates calcarifer from the Northern Territory of
Australia. 2006 Viral Nervous Necrosis
International Symposium , Hiroshima, Japan:
Japanese Society of Fish Pathology.
Di Fiore, L., Taylor, D., de Silva, K., Bosward,
K., Begg, D., Emery, D., Whittington, R. (2006).
Identificaiton of differentially expressed genes in uninfected and Mycobacterium paratuberculosis
(M.ptb. ) infected sheep. The 8th International
Colloquium on Paratuberculosis , N/A: N/A.
Di Fiore, L., Taylor, D., de Silva, K., Bosward,
K., Begg, D., Emery, D., Whittington, R. (2006).
Identification of differentially expressed genes in uninfected and Mycobacterium paratuberculosis
(M. ptb.) infected sheep. 8th International
Colloquium on Paratuberculosis ICP 2005 ,
United States: International Association for
Paratuberculosis.
Begg, D., Griffin, F. (2006). Immune parameters and vaccine efficacy in Mycobacterium avium subspecies paratuberculosis experimentally infected sheep. 8th International Colloquium on
Paratuberculosis ICP 2005 , United States:
International Association for Paratuberculosis.
Bosward, K., Begg, D., de Silva, K., Di Fiore, L.,
Taylor, D., Emery, D., Whittington, R. (2006).
Optimisation of the interferon-gamma assay to maximise responses to M. ptb. antigen in sheep.
8th International Colloquium on
Paratuberculosis ICP 2005 , United States:
International Association for Paratuberculosis.
Hick, P., Gore, K., Taylor, D., Begg, D., Schipp,
G., Bosmans, J., Humphrey, J., Melville, L.,
Whittington, R. (2006). Permissivity of the
SSN-1 cell line to Lates calcarifer nervous necrosis virus. 2006 Viral Nervous Necrosis
International Symposium , Hiroshima, Japan:
Japanese Society of Fish Pathology.
Begg, D., de Silva, K., Di Fiore, L., Taylor, D.,
Whittington, R. (2006). Seeing spots, using the
ELISPOT assay to detect M. avium subspecies paratuberculosis infection in sheep. Australasian
Society for Immunology Conference 2006 ,
Australia: Australasian Society for Immunology.
2005
Bower (Goldsmith), K., Begg, D., Di Fiore, L.,
Whittington, R. (2005). Detection of
Mycobacteria from blood. MLA OJD Harvest
Year Conference , North Sydney, N.S.W: Meat &
Livestock Australia Ltd.
de Silva, K., Begg, D., Di Fiore, L., Taylor, D.,
Emery, D., Whittington, R. (2005). Early cellular responses in ovine Johne's disease. MLA OJD
Harvest Year Conference , North Sydney, N.S.W:
Meat & Livestock Australia Ltd.
Begg, D., Bosward, K., de Silva, K., Di Fiore, L.,
Taylor, D., Whittington, R. (2005). ELISPOT - new methods for detecting IFN-y. MLA OJD
Harvest Year Conference , North Sydney, N.S.W:
Meat & Livestock Australia Ltd.
Begg, D., O'Brien, R., Mackintosh, C., Griffin,
F. (2005). Experimental infection model for
Johne's disease in sheep. Infection and Immunity ,
73(9), 5603-5611.
Bosward, K., Begg, D., de Silva, K., Di Fiore, L.,
Taylor, D., Whittington, R. (2005). Manipulation of the Interferon - gamma assay to maximise responses to M. ptb antigen in sheep. MLA OJD
Harvest Year Conference , North Sydney, N.S.W:
Meat & Livestock Australia Ltd.
Taylor, D., Gumber, S., de Silva, K., Bower
(Goldsmith), K., Di Fiore, L., Begg, D.,
Whittington, R. (2005). Molecular approaches to studying the host-parasite interaction. MLA OJD
Harvest Year Conference , North Sydney, N.S.W:
Meat & Livestock Australia Ltd.
Begg, D., Griffin, F. (2005). Vaccination of sheep against M. paratuberculosis: Immune parameters and protective efficacy. Vaccine ,
23(42), 4999-5008.
2004
Begg, D., Kemp, R., Griffin, F. (2004). Normal levels of immunocompetence in possums
(Trichosurus vulpecula) exposed to different laboratory housing conditions post capture.
Immunology and Cell Biology , 82(3), 253-256.
2003
Begg, D., Crosbie, P., Griffin, F. (2003). Ovine
Johne's disease: Comparative immunological responses in peripheral blood and gut associated lymphoid tissue. Australasian Society for
Immunology Conference 2003 , Australia:
Australasian Society for Immunology.