Publications for Wayne Hawthorne
Publications for Wayne Hawthorne
2016
Rayat, G., Gazda, L., Hawthorne, W., Hering, B.,
Hosking, P., Matsumoto, S., Rajotte, R. (2016).
First update of the International
Xenotransplantation Association consensus
statement on conditions for undertaking clinical
trials of porcine islet products in type 1 diabetes Chapter 3: Porcine islet product manufacturing
and release testing criteria. Xenotransplantation,
23(1), 38-45. <a
href="http://dx.doi.org/10.1111/xen.12225">[Mo
re Information]</a>
Cooper, D., Bottino, R., Gianello, P., Graham,
M., Hawthorne, W., Kirk, A., Korsgren, O.,
Park, C., Weber, C. (2016). First update of the
International Xenotransplantation Association
consensus statement on conditions for
undertaking clinical trials of porcine islet
products in type 1 diabetes—Chapter 4:
pre-clinical efficacy and complication data
required to justify a clinical trial.
Xenotransplantation, 23(1), 46-52. <a
href="http://dx.doi.org/10.1111/xen.12226">[Mo
re Information]</a>
Joglekar, M., Trivedi, P., Kay, T., Hawthorne,
W., O'Connell, P., Jenkins, A., Hardikar, A.,
Thomas, H. (2016). Human islet cells are killed
by BID-independent mechanisms in response to
FAS ligand. Apoptosis, 21(4), 379-389. <a
href="http://dx.doi.org/10.1007/s10495-016-121
2-y">[More Information]</a>
Hameed, A., Yu, T., Yuen, L., Lam, V., Ryan,
B., Allen, R., Laurence, J., Hawthorne, W.,
Pleass, H. (2016). Use of the Harmonic Scalpel
in Cold Phase Recovery of the Pancreas for
Transplantation: The Westmead Technique.
Transplant International, 29(5), 636-638. <a
href="http://dx.doi.org/10.1111/tri.12777">[Mor
e Information]</a>
2015
Stewart, J., Tarantal, A., Hawthorne, W.,
Salvaris, E., O'Connell, P., Nottle, M., D'Apice,
A., Cowan, P., Kearns-Jonker, M. (2015).
Clonidine inhibits anti-non-Gal IgM
xenoantibody elicited in multiple pig-to-primate
models. Xenotransplantation, 22(6), 413-426. <a
href="http://dx.doi.org/10.1111/xen.12199">[Mo
re Information]</a>
Park, C., Bottino, R., Hawthorne, W. (2015).
Current status of islet xenotransplantation.
International Journal of Surgery, 23, 261-266.
<a
href="http://dx.doi.org/10.1016/j.ijsu.2015.07.70
3">[More Information]</a>
Kim, H., Hawthorne, W., Kang, H., Lee, Y.,
Hwang, J., Hurh, S., Ro, H., Jeong, J., Cho, B.,
Yang, J., et al (2015). Human thrombomodulin
regulates complement activation as well as the
coagulation cascade in xeno-immune response.
Xenotransplantation, 22(4), 260-272. <a
href="http://dx.doi.org/10.1111/xen.12173">[Mo
re Information]</a>
Marathe, C., Drogemuller, C., Marathe, J.,
Loudavaris, T., Hawthorne, W., O'Connell, P.,
Radford, T., Kay, T., Horowitz, M., Coates, P., et
al (2015). Islet Cell Transplantation in Australia:
Screening, Remote Transplantation, and Incretin
Hormone Secretion in Insulin Independent
Patients. Hormone And Metabolic Research,
47(1), 16-23. <a
href="http://dx.doi.org/10.1055/s-0034-1389941
">[More Information]</a>
Augstein, P., Naselli, G., Loudovaris, T.,
Hawthorne, W., Campbell, P., Bandala-Sanchez,
E., Rogers, K., Heinke, P., Thomas, H., Kay, T.,
et al (2015). Localization of dipeptidyl
peptidase-4 (CD26) to human pancreatic ducts
and islet alpha cells. Diabetes Research and
Clinical Practice, 110(3), 291-300. <a
href="http://dx.doi.org/10.1016/j.diabres.2015.10
.010">[More Information]</a>
Jimenez, E., Davies, S., Phillips, P., O'Connell,
P., Hawthorne, W. (2015). Long-term cultured
neonatal islet cell clusters demonstrate better
outcomes for reversal of diabetes: In vivo and
molecular profiles. Xenotransplantation, 22(2),
114-123. <a
href="http://dx.doi.org/10.1111/xen.12151">[Mo
re Information]</a>
Chung, H., Lam, V., Yuen, L., Ryan, B.,
O'Connell, P., Chapman, J., Hawthorne, W.,
Pleass, H. (2015). Renal transplantation: better
fat than thin. Journal of Surgical Research,
194(2), 644-652. <a
href="http://dx.doi.org/10.1016/j.jss.2013.12.027
">[More Information]</a>
Tran, H., Tran, K., Turingan, I., Zajkowska, M.,
Lam, V., Hawthorne, W. (2015). Single-incision
laparoscopic inguinal herniorraphy with
telescopic extraperitoneal dissection: technical
aspects and potential benefits. Hernia, 19(3),
407-416. <a
href="http://dx.doi.org/10.1007/s10029-015-134
9-6">[More Information]</a>
Tran, H., Tran, K., Zajkowska, M., Lam, V.,
Hawthorne, W. (2015). Single-incision
laparoscopic repair of spigelian hernia. Journal
of the Society of Laparoendoscopic Surgeons,
19(1), 1-7. <a
href="http://dx.doi.org/10.4293/JSLS.2015.0016
44">[More Information]</a>
Tran, H., Tran, K., Zajkowska, M., Lam, V.,
Hawthorne, W. (2015). Single-Port Onlay Mesh
Publications for Wayne Hawthorne
Repair of Recurrent Inguinal Hernias after Failed
Anterior and Laparoscopic Repairs. Journal of
the Society of Laparoendoscopic Surgeons,
19(1), 1-10. <a
href="http://dx.doi.org/10.4293/JSLS.2014.0021
2">[More Information]</a>
2014
Guo, F., Xing, X., Hawthorne, W., Dong, Q., Ye,
B., Zhang, J., Liang, Q., Nie, W., Wang, W.
(2014). Characterization of PERV in a new
conserved pig herd as potential donor animals for
xenotransplantation in China. Virology Journal,
11, 1-9. <a
href="http://dx.doi.org/10.1186/s12985-014-021
2-1">[More Information]</a>
Hawthorne, W., Salvaris, E., Phillips, P.,
Hawkes, J., Liuwantara, D., Burns, H., Barlow,
H., Stewart, A., Peirce, S., Hu, M., O'Connell, P.,
et al (2014). Control of IBMIR in Neonatal
Porcine Islet Xenotransplantation in Baboons.
American Journal of Transplantation, 14(6),
1300-1309. <a
href="http://dx.doi.org/10.1111/ajt.12722">[Mor
e Information]</a>
Jin, X., Wang, Y., Hawthorne, W., Hu, M., Yi,
S., O'Connell, P. (2014). Enhanced Suppression
of the Xenogeneic T-Cell Response in Vitro by
Xenoantigen Stimulated and Expanded
Regulatory T Cells. Transplantation, 97(1),
30-38. <a
href="http://dx.doi.org/10.1097/TP.0b013e3182a
860fa">[More Information]</a>
Wong, M., Tso, A., Ali, M., Hawthorne, W.,
Manolios, N. (2014). Novel T-cell inhibiting
peptides delay the onset of Type 1 diabetes in
non-obese diabetic mice. Diabetes &
Metabolism, 40, 229-234. <a
href="http://dx.doi.org/10.1016/j.diabet.2014.01.
007">[More Information]</a>
Tran, H., Turingan, I., Tran, K., Zajkowska, M.,
Lam, V., Hawthorne, W. (2014). Potential
benefits of single-port compared to multiport
laparoscopic inguinal herniorraphy: a prospective
randomized controlled study. Hernia, 18(5),
731-744. <a
href="http://dx.doi.org/10.1007/s10029-014-126
1-5">[More Information]</a>
Brady, J., Harrison, L., Goodman, D., Cowan, P.,
Hawthorne, W., O'Connell, P., Sutherland, R.,
Lew, A. (2014). Preclinical screening for acute
toxicity of therapeutic monoclonal antibodies in
a hu-SCID model. Clinical & Translational
Immunology, 3(12), 1-7.
Stewart, J., Tarantal, A., Hawthorne, W.,
Salvaris, E., O'Connell, P., Nottle, M., D'Apice,
A., Cowan, P., Kearns-Jonker, M. (2014).
Rhesus monkeys and baboons develop clotting
factor VIII inhibitors in response to porcine
endothelial cells or islets. Xenotransplantation,
21(4), 341-352. <a
href="http://dx.doi.org/10.1111/xen.12100">[Mo
re Information]</a>
Tran, H., Tran, K., Zajkowska, M., Lam, V.,
Hawthorne, W. (2014). Single-Incision
Laparoscopic Intraperitoneal Onlay Mesh Repair
for the Treatment of Multiple Recurrent Inguinal
Hernias. Journal of the Society of
Laparoendoscopic Surgeons, 18(3), 1-8. <a
href="http://dx.doi.org/10.4293/JSLS.2014.0035
4">[More Information]</a>
Chen, Y., Stewart, J., Gunthart, M., Hawthorne,
W., Salvaris, E., O'Connell, P., Nottle, M.,
d'Apice, A., Cowan, P., Kearns-Jonker, M.
(2014). Xenoantibody response to porcine islet
cell transplantation using GTKO, CD55, CD59,
and fucosyltransferase multiple transgenic
donors. Xenotransplantation, 21(3), 244-253. <a
href="http://dx.doi.org/10.1111/xen.12091">[Mo
re Information]</a>
2013
Cantley, J., Walters, S., Jung, M., Weinberg, A.,
Cowley, M., Whitworth, P., Kaplan, W.,
Hawthorne, W., O'Connell, P., Weir, G., et al
(2013). A Preexistent Hypoxic Gene Signature
Predicts Impaired Islet Graft Function and
Glucose Homeostasis. Cell Transplantation,
22(11), 2147-2159. <a
href="http://dx.doi.org/10.3727/096368912X658
728">[More Information]</a>
Brady, J., Sutherland, R., Hancock, M.,
Kitsoulis, S., Lahoud, M., Phillips, P.,
Hawthorne, W., d'Apice, A., Cowan, P.,
Harrison, L., O'Connell, P., et al (2013).
Anti-CD2 producing pig xenografts effect
localized depletion of human T cells in a huSCID
model. Xenotransplantation, 20(2), 100-109. <a
href="http://dx.doi.org/10.1111/xen.12025">[Mo
re Information]</a>
Stokes, R., Cheng, K., Deters, N., Lau, S.,
Hawthorne, W., O'Connell, P., Stolp, J., Grey, S.,
Loudovaris, T., Kay, T., Gunton, J., et al (2013).
Hypoxia-inducible factor-1α (HIF-1α)
potentiates β-cell survival after islet
transplantation of human and mouse islets. Cell
Transplantation, 22(2), 253-266. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=22710383">[More Information]</a>
Hu, M., Wang, C., Zhang, G., Saito, M., Wang,
Y., Fernandez, M., Wang, Y., Wu, H.,
Hawthorne, W., Jones, C., O'Connell, P., Bishop,
A., Sharland, A., Alexander, S., et al (2013).
Infiltrating Foxp3+ regulatory T cells from
spontaneously tolerant kidney allografts
demonstrate donor-specific tolerance. American
Publications for Wayne Hawthorne
Journal of Transplantation, 13, 2819-2830. <a
href="http://dx.doi.org/10.1111/ajt.12445">[Mor
e Information]</a>
O'Connell, P., Holmes-Walker, J., Goodman, D.,
Hawthorne, W., Loudovaris, T., Gunton, J.,
Thomas, H., Grey, S., Drogemuller, C., Ward,
G., et al (2013). Multicenter Australian Trial of
Islet Transplantation: Improving Accessibility
and Outcomes. American Journal of
Transplantation, 13(7), 1850-1858. <a
href="http://dx.doi.org/10.1111/ajt.12250">[Mor
e Information]</a>
Gerace, D., Ren, B., Hawthorne, W., Byrne, M.,
Phillips, P., O'Brien, B., Nassif, N., Alexander,
I., Simpson, A. (2013). Pancreatic
Transdifferentiation in Porcine Liver Following
Lentiviral Delivery of Human Furin-Cleavable
Insulin. Transplantation Proceedings, 45(5),
1869-1874. <a
href="http://dx.doi.org/10.1016/j.transproceed.20
13.01.051">[More Information]</a>
Hu, M., Wu, J., Zhang, G., Wang, Y., Watson,
D., Yi, S., Hawthorne, W., O'Connell, P.,
Alexander, S. (2013). Selective Depletion of
Alloreactive T cells Leads to Long-Term Islet
Allograft Survival Across a Major
Histocompatibility Complex Mismatch in
Diabetic Mice. Cell Transplantation, 22(10),
1929-1941. <a
href="http://dx.doi.org/10.3727/096368912X658
025">[More Information]</a>
Thwaites, S., Lam, V., Yao, J., Kable, K.,
Jenkins, L., Chen, C., Robertson, P., Hawthorne,
W., Ryan, B., Pleass, H., Allen, R. (2013).
Surgical Morbidity of Simultaneous Kidney and
Pancreas Transplantation: A Single-Centre
Experience in the Tacrolimus Era. ISRN
Transplantation, 2013, 1-6. <a
href="http://dx.doi.org/10.5402/2013/685850">[
More Information]</a>
O'Connell, P., Cowan, P., Hawthorne, W., Yi, S.,
Lew, A. (2013). Transplantation of Xenogeneic
Islets: Are We There Yet? Current Diabetes
Reports, 13(5), 687-694. <a
href="http://dx.doi.org/10.1007/s11892-013-041
3-9">[More Information]</a>
2012
Yi, S., Ji, M., Wu, J., Ma, X., Phillips, P.,
Hawthorne, W., O'Connell, P. (2012). Adoptive
Transfer With In Vitro Expanded Human
Regulatory T Cells Protects Against Porcine Islet
Xenograft Rejection via Interleukin-10 in
Humanized Mice. Diabetes, 61(5), 1180-1191.
<a
href="http://dx.doi.org/10.2337/db11-1306">[M
ore Information]</a>
Thwaites, S., Gurung, B., Yao, J., Kable, K.,
Robertson, P., Ryan, B., Lam, V., Pleass, H.,
Chapman, J., Hawthorne, W., Allen, R. (2012).
Excellent Outcomes of Simultaneous Pancreas
Kidney Transplantation in Patients From Rural
and Urban Australia: A National Service
Experience. Transplantation, 94(12), 1230-1235.
<a
href="http://dx.doi.org/10.1097/TP.0b013e31827
08e04">[More Information]</a>
Campbell, P., Weinberg, A., Chee, J., Mariana,
L., Ayala, R., Hawthorne, W., O'Connell, P.,
Loudovaris, T., Cowley, M., Kay, T., et al
(2012). Expression of Pro- and Anti-apoptotic
Molecules of the Bcl-2 Family in Human Islets
Postisolation. Cell Transplantation, 21(1), 49-60.
<a
href="http://dx.doi.org/10.3727/096368911X566
262">[More Information]</a>
Cowley, M., Weinberg, A., Zammit, N., Walters,
S., Hawthorne, W., Loudovaris, T., Thomas, H.,
Kay, T., Gunton, J., Alexander, S., O'Connell, P.,
et al (2012). Human islets express a marked
proinflammatory molecular signature prior to
transplantation. Cell Transplantation, 21(9),
2063-2078. <a
href="http://dx.doi.org/10.3727/096368911X627
372">[More Information]</a>
Tran, H., Saliba, L., Chandratnam, E., Turingan,
I., Hawthorne, W. (2012). Strategies to Minimize
Adhesions to Intraperitoneally Placed Mesh in
Laparoscopic Ventral Hernia Repair. Journal of
the Society of Laparoendoscopic Surgeons,
16(1), 89-94. <a
href="http://dx.doi.org/10.4293/108680812X132
91597716140">[More Information]</a>
2011
Lucewicz, A., Wong, G., Lam, V., Hawthorne,
W., Allen, R., Craig, J., Pleass, H. (2011).
Management of Primary Symptomatic
Lymphocele After Kidney Transplantation: A
Systematic Review. Transplantation, 92(6),
663-673. <a
href="http://dx.doi.org/10.1097/TP.0b013e31822
a40ef">[More Information]</a>
Chew, M., Hawthorne, W., Bendall, J., Whereat,
S., Huang, S., Ting, I., Simond, D., McLean, A.
(2011). No beneficial effects of levosimendan in
acute
porcine endotoxaemia. Acta Anaesthesiologica
Scandinavica: an international journal of
anaesthesiology and intensive care, pain and
emergency medicine, 55(7), 851-861. <a
href="http://dx.doi.org/10.1111/j.1399-6576.201
1.02436.x">[More Information]</a>
Hawthorne, W., Simond, D., Stokes, R., Patel,
A., Walters, S., Burgess, J., O'Connell, P. (2011).
Pre-clinical model of composite foetal pig
Publications for Wayne Hawthorne
pancreas fragment/renal xenotransplantation to
treat renal failure and diabetes.
Xenotransplantation, 18(6), 390-399. <a
href="http://dx.doi.org/10.1111/j.1399-3089.201
1.00681.x">[More Information]</a>
Hawthorne, W., Simond, D., Stokes, R., Patel,
A., Walters, S., Burgess, J., O'Connell, P. (2011).
Subcapsular Fetal Pig Pancreas Fragment
Transplantation Provides Normal Blood Glucose
Control in a Preclinical Model of Diabetes.
Transplantation, 91(5), 515-521. <a
href="http://dx.doi.org/10.1097/TP.0b013e31820
79474">[More Information]</a>
Ji, M., Yi, S., Smith-Hurst, H., Phillips, P., Wu,
J., Hawthorne, W., O'Connell, P. (2011). The
Importance of Tissue Factor Expression by
Porcine NICC in Triggering IBMIR in the
Xenograft Setting. Transplantation, 91(8),
841-846. <a
href="http://dx.doi.org/10.1097/TP.0b013e31821
06091">[More Information]</a>
2010
Lam, V., Pleass, H., Hawthorne, W., Allen, R.
(2010). Evolution of pancreas transplant surgery.
ANZ Journal of Surgery, 80(6), 411-418. <a
href="http://dx.doi.org/10.1111/j.1445-2197.201
0.05309.x">[More Information]</a>
Wong, M., Hawthorne, W., Manolios, N. (2010).
Gene Therapy in Diabetes. Self Nonself, 1(3),
165-175. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=21487475">[More Information]</a>
Wang, W., Liu, S., Zheng, W., Gao, F.,
Hawthorne, W., Yi, S. (2010). Hepatic artery vs.
portal vein infusion of microbeads: a large
animal pre-clinical model evaluating the
intrahepatic capacity for cell infusion and
imaging. Xenotransplantation, 17(3), 207-214.
<a
href="http://dx.doi.org/10.1111/j.1399-3089.201
0.00580.x">[More Information]</a>
Cheng, K., Ho, K., Stokes, R., Scott, C., Lau, S.,
Hawthorne, W., O'Connell, P., Loudovaris, T.,
Kay, T., Kulkarni, R., Biankin, A., Kench, J.,
Gunton, J., et al (2010). Hypoxia-inducible
factor-1alpha regulates beta cell function in
mouse and human islets. Journal of Clinical
Investigation, 120(6), 2171-2183. <a
href="http://dx.doi.org/10.1172/JCI35846">[Mor
e Information]</a>
2009
Lam, V., Laurence, J., Robertson, P., Hawthorne,
W., Ryan, B., Lau, H., Allen, R., Pleass, H.
(2009). En bloc paediatric kidney transplant: is
this the best use of a scarce resource? ANZ
Journal of Surgery, 79(1-2), 27-32. <a
href="http://dx.doi.org/10.1111/j.1445-2197.200
8.04793.x">[More Information]</a>
Hawthorne, W., Xing, X., Yi, S., Simond, D.,
Dong, Q., Ye, B., Tong, Q., Ye, Z., Wang, W.
(2009). Investigation of porcine endogenous
retrovirus in the conservation population of
ningxiang pig. Transplantation Proceedings,
41(10), 4389-4393. <a
href="http://dx.doi.org/10.1016/j.transproceed.20
09.09.051">[More Information]</a>
Londrigan, S., Brady, J., Sutherland, R., Cowan,
P., d'Apice, A., Hawthorne, W., O'Connell, P.,
Lew, A. (2009). Optimizing transduction of pig
islet cell clusters for xenotransplantation.
Xenotransplantation, 16(1), 45-46. <a
href="http://dx.doi.org/10.1111/j.1399-3089.200
9.00511.x">[More Information]</a>
Akima, S., Hawthorne, W., Favaloro, E., Patel,
A., Blyth, K., Mudaliar, M., Chapman, J.,
O'Connell, P. (2009). Tirofiban and Activated
Protein C Synergistically Inhibit the Instant
Blood Mediated Inflammatory Reaction (IBMIR)
from Allogeneic Islet Cells Exposure to Human
Blood. American Journal Of Transplantation, 9,
1533-1540. <a
href="http://dx.doi.org/10.1111/j.1600-6143.200
9.02673.x">[More Information]</a>
2008
Feller, J., Simpson, A., Nelson, M., O'Connell,
P., Swan, M., Hawthorne, W., Tao, C., O'Brien,
B. (2008). Growth Promoting Effect of Rh(D)
Antibody on Human Pancreatic Islet Cells.
Journal of Clinical Endocrinology and
Metabolism, 93(9), 3560-3567. <a
href="http://dx.doi.org/10.1210/jc.2008-0510">[
More Information]</a>
Wu, J., Yi, S., Ouyang, L., Jimenez, E., Simond,
D., Wang, W., Wang, Y., Hawthorne, W.,
O'Connell, P. (2008). In Vitro Expanded Human
CD4+CD25+ Regulatory T Cells are Potent
Suppressors of T-Cell-Mediated Xenogeneic
Responses. Transplantation, 85(12), 1841-1848.
<a
href="http://dx.doi.org/10.1097/TP.0b013e31817
34793">[More Information]</a>
Fu, Y., Yi, S., Wu, J., Jimenez-Vera, E., Simond,
D., Hawthorne, W., O'Connell, P. (2008). In
vitro suppression of xenoimmune-mediated
macrophage activation by human CD4+CD25+
regulatory T cells. Transplantation, 86(6),
865-874. <a
href="http://dx.doi.org/10.1097/TP.0b013e31818
530fd">[More Information]</a>
Jung, K., Simond, D., Moran, C., Hawthorne,
W., Jeon, J., Jin, D., Lee, J. (2008). Investigation
of Deletion Variation and Methylation Patterns
Publications for Wayne Hawthorne
in the 5' LTR of Porcine Endogenous
Retroviruses. Asian-Australasian Journal of
Animal Sciences, 21(11), 1572-1575.
Fu, Y., Lu, X., Yi, S., O'Hara, J., Hawthorne, W.,
Hucker, K., O'Connell, P. (2008). Selective
rejection of porcine islet xenografts by
macrophages. Xenotransplantation, 15(5),
307-312. <a
href="http://dx.doi.org/10.1111/j.1399-3089.200
8.00486.x">[More Information]</a>
Horton, P., Hawthorne, W., Walters, S., Patel, T.,
Stewart, G., Allen, R., Chapman, J. (2008).
Tolerance Induction in a Large-Animal Model
Using Total Lymphoid Irradiation and
Intrathymic Bone Marrow. Transplantation,
86(12), 1830-1836. <a
href="http://dx.doi.org/10.1097/TP.0b013e31819
10e67">[More Information]</a>
2007
Chandra, A., Ouyang, L., Wong, J., Ha, H.,
Walters, S., Patel, A., Hawthorne, W., Yi, S.
(2007). Association between islet xenograft
rejection mediated by activated macrophages and
upregulated chemokines. Zhongnan Daxue
Xuebao (Yixue Ban), 32(1), 26-35. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17344583">[More Information]</a>
Chandra, A., Ouyang, L., Yi, S., Wong, J., Ha,
H., Walters, S., Patel, A., Stokes, R., Jardine, M.,
Hawthorne, W., O'Connell, P. (2007).
Chemokine and toll-like receptor signaling in
macrophage mediated islet xenograft rejection.
Xenotransplantation, 14(1), 48-59. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17214704">[More Information]</a>
Londrigan, S., Brady, J., Sutherland, R.,
Hawthorne, W., Thomas, H., Jhala, G., Cowan,
P., Kay, T., O'Connell, P., Lew, A. (2007).
Evaluation of promoters for driving efficient
transgene expression in neonatal porcine islets.
Xenotransplantation, 14(2), 119-125. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17381686">[More Information]</a>
Yi, S., Wang, Y., Chandra, A., O'Hara, J., Wu, J.,
Ouyang, L., Burgess, J., Hawthorne, W., Wu, H.,
Chadban, S., O'Connell, P. (2007). Requirement
of MyD88 for macrophage-mediated islet
xenograft rejection after adoptive transfer.
Transplantation, 83(5), 615-623. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17353783">[More Information]</a>
2006
O'Connell, P., Hawthorne, W., Holmes-Walker,
D., Nankivell (Nankievell), B., Gunton, J., Patel,
A., Walters, S., Pleass, H., Allen, R., Chapman,
J. (2006). Clinical islet transplantation in type 1
diabetes mellitus: results of Australia's first trial.
Medical Journal of Australia, 184(5), 221-225.
<a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
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&list_uids=16515432">[More Information]</a>
Akima, S., Hawthorne, W., Koutts, J., Patel, A.,
Burgess, J., O'Hara, J., Mudaliar, Y., Favaloro,
E., O'Connell, P. (2006). Differences in the
efficacy of recombinant human activated protein
C against allogeneic and xenogeneic IBMIR.
84(3), A16-A16.
Hawthorne, W., Patel, A., O'Hara, J., Akima, S.,
Salvaris, E., Nottle, M., d'Aspice, A., Cowan, P.,
O'Connell, P. (2006). Elimination of the alpha
Gal antigen on NICC reduces ibmir following
exposure of pig NICC to human blood. 24th
Annual Scientific Meeting of the Transplantation
Society of Australia and New Zealand (2006),
Australia: Nature Publishing Group.
O'Connell, P., Lew, A., Cowan, P., Londrigan,
S., Hawthorne, W., Nottle, M., d'Apice, A.
(2006). Islet xenotransplantation: progress
towards a clinical therapy. Current Opinion in
Organ Transplantation, 11(2), 174-179.
Chandra, A., Wong, J., Yi, S., Ha, H., Patel, A.,
O'Connell, P., Hawthorne, W. (2006). Lack of
IL-15 reduces recruitment of xenoreactive
leukocytes into discordant islet xenografts but
does not prolong graft survival. 24th Annual
Scientific Meeting of the Transplantation Society
of Australia and New Zealand (2006), Australia:
Nature Publishing Group.
Simond, D., Moran, C., Garkavenko, O.,
O'Connell, P., Hawthorne, W. (2006). Real-time
PCR detection of porcine endogenous
retroviruses. 24th Annual Scientific Meeting of
the Transplantation Society of Australia and New
Zealand (2006), Australia: Nature Publishing
Group.
Harvey (Holyoake), P., Stevenson, J., Moran, C.,
Stokes, R., Kirk, E., Sugo, E., Hawthorne, W.
(2006). The first reported case of congenital
heart defects in pigs in Australia. 19th
International Pig Veterinary Society Congress
IPVS 2006, Denmark: International Pig
Veterinary Society.
Lam, V., Wong, K., Hawthorne, W., Ryan, B.,
Lau, H., Robertson, P., Allen, R., Pleass, H.
(2006). The linear cutting stapler for enteric
anastomosis: a new technique in pancreas
transplantation. Transplant International, 19(11),
915-918. <a
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Harvey (Holyoake), P., Stevenson, J., Moran, C.,
Stokes, R., Kirk, E., Sugo, E., Hawthorne, W.
(2006). The occurrence of congenital heart
defects in an inbred herd of pigs in Australia.
Australian Veterinary Journal, 84(4), 129-133.
<a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=16629192">[More Information]</a>
Varcoe, R., Mikhail, M., Guiffre, A., Pennings,
G., Vicaretti, M., Hawthorne, W., Fletcher, J.,
Medbury, H. (2006). The role of the fibrocyte in
intimal hyperplasia. Journal of Thrombosis and
Haemostasis, 4(5), 1125-1133. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
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&list_uids=16689767">[More Information]</a>
Hawthorne, W., Stokes, R., Patel, A., Burgess, J.,
Walters, S., Simond, D., O'Connell, P. (2006).
Westran fetal pig pancreas fragment transplants
provide long-term normoglycaemia in adult pi.
24th Annual Scientific Meeting of the
Transplantation Society of Australia and New
Zealand (2006), Australia: Nature Publishing
Group.
2005
Wong, K., Kable, K., Hawthorne, W., Robertson,
P., Chan, K., Nankivell (Nankievell), B.,
O'Connell, P., Chapman, J., Lau, H., Pleass, H.,
Allen, R. (2005). A comparison of 2 surgical
techniques in pancreas transplantation.
Immunology and Cell Biology, 83(4), A23-A24.
Lee, J., Simond, D., Hawthorne, W., Walters, S.,
Patel, A., Smith, D., O'Connell, P., Moran, C.
(2005). Characterization of the swine major
histocompatibility complex alleles at eight loci in
Westran pigs. Xenotransplantation, 12(4),
303-307. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=15943779">[More Information]</a>
Benseler, V., Bishop, A., Ch'ng, K., Watson, J.,
Wang, C., Dahlke, M., Koutalistras, N., Watts,
A., Hawthorne, W., McKenzie, P., Hennessy, A.,
Pleass, H., Chadban, S., Schlitt, H., McCaughan,
G., et al (2005). Development of a primate model
to evaluate strategies to achieve long term renal
allograft acceptance. Immunology and Cell
Biology, 83(4 Suppl.), A26-A26.
O'Connell, P., Hawthorne, W., Simond, D.,
Chapman, J., Chen, Y., Patel, A., Walters, S.,
Burgess, J., Weston, L., Stokes, R., Moran, C.,
Allen, R. (2005). Genetic and Functional
evaluation of the level of inbreeding of the
Westran pig: a herd with potential for use in
xenotransplantation. Xenotransplantation, 12(4),
308-315. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
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&list_uids=15943780">[More Information]</a>
Yi, S., Ouyang, L., Ha, H., O'Hara, J., Chandra,
A., Akima, S., Hawthorne, W., Patel, A., Stokes,
R., O'Connell, P. (2005). Involvement of CCR5
Signaling in Macrophage
Recruitment to Porcine Islet Xenografts.
Transplantation, 80(10), 1468-1475. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
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&list_uids=16340793">[More Information]</a>
Gunton, J., Kulkarni, R., Yim, S., Okada, T.,
Hawthorne, W., Tseng, Y., Roberson, R.,
Ricordi, C., O'Connell, P., Gonzalez, F., et al
(2005). Loss of ARNT/HIF1beta mediates
altered gene expression and pancreatic-islet
dysfunction in human type 2 diabetes. Cell,
122(3), 337-349. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=16096055">[More Information]</a>
2004
Fletcher, J., Ao, P., Hawthorne, W. (2004).
Antiproliferative Effects Of Low Molecular
Weight Heparin. ANZ Journal of Surgery, 74(9),
793-796.
Huang, P., Hawthorne, W., Fletcher, J. (2004).
Time Course Of Cellular Proliferation,
Neointima Formation, Apoptosis And Its Fas
Pathway Following Dacron Patch Graft
Implantation In Sheep Carotid Artery.
Cardiovascular Pathology, 13(3 Supplement 1),
S118.
2003
Yi, S., Hawthorne, W., Lehnert, A., Ha, H.,
Wong, J., Rooijen, N., Davey, K., Patel, A.,
Walters, S., Chandra, A., O'Connell, P. (2003). T
Cell-Activated Macrophages Are Capable of
Both
Recognition and Rejection of Pancreatic Islet
Xenografts. The Journal of Immunology, 170(5),
2750-2758.
2002
Yi, S., Feng, X., Hawthorne, W., Patel, A.,
Walters, S., O'Connel, P. (2002). CD4+ T Cells
initiate Pancreatic Islet Xenograft rejection via
an interferon-y-Dependent recruitment of
macrophages and natural killer cells.
Transplantation, 73(3), 437-446.
Tso, C., Skinner, M., Hawthorne, W., Fletcher, J.
(2002). Matrigel-coated stents reduce intimal
thickening in a large animal vascular stent
Model. International Angiology, 21(3), 244-249.
Publications for Wayne Hawthorne
Hawthorne, W., Pye, A., Vicaretti, M., Fletcher,
J. (2002). New Methodology for Assessment of
Intimal Hyperplasia of Vascular Prostheses. ANZ
Journal of Surgery, 72(9), 623-627.
Huang, P., Hawthorne, W., Ao, P., Angeli, G.,
Medbury, H., Fletcher, J. (2002). Perigraft
adventitia and intima remodeling after synthetic
patch implantation in sheep carotid artery: Role
of apoptosis and proliferation. Journal Of
Vascular Surgery, 36(2), 371-378.
Hawthorne, W., Ao, P., Fletcher, J. (2002).
Vascular closure staples reducae intimal
hyperplasia in prosthesis implantation. ANZ
Journal of Surgery, 72(12), 862-866.
2001
Lehnert, A., Hawthorne, W., O'Connell, P.,
Mottram, P., Han, W., Walters, S., Patel, A.,
Cowan, P., d'Apice, A. (2001). Blockage of the
cd28 and cd40 pathways result in the acceptance
of pig and rat islet xenografts but not rat cardiac
grafts in mice. Transplant Immunology, 9, 51-56.
Huang, P., Hawthorne, W., Ao, P., Fletcher, J.,
Angeli, G., Medbury,, H. (2001). Calcium
channel antagonist verapamil inhibits neoinitimal
formation and enhances apoptosis in a vas. The
American Journal Of Surgery, 181(6), 492-498.
Ao, P., Hawthorne, W., Fletcher, J., Bobryshev,,
Y., Inder,, S., Cherian, S., Lord,, R. (2001).
Colonisation of prosthetic grafts by
immunocompetent cells in a sheep model.
Vascular, 9(2), 166-176.
Allen, R., Nankivell (Nankievell), B.,
Hawthorne, W., O'Connell, P., Chapman, J.
(2001). Pancreas and islet transplantation: an
unfinished journey. Transplantation
Proceedings, 33, 3485-3488.
2000
Hawthorne, W., Cachia, A., Walters, S., Patel,
A., Clarke, J., O'Connell, P., Chapman, J., Allen,
R. (2000). A large-animal model to evaluate the
clinical potential of fetal pig pancreas fragment
transplantation. Cell Transplantation, 9,
867-875.
Ao, P., Hawthorne, W., Vicaretti, M., Fletcher, J.
(2000). Development of Intimal Hyperplasia in
six different Vascular Prostheses. European
Journal of Vascular and Endovascular Surgery,
20, 241-249.
Horton, P., Hawthorne, W., Walters, S., Patel,
A., O'Connell, P., Chapman, J., Allen, R. (2000).
Induction of allogenic islet tolerance in a
large-animal model. Cell Transplantation, 9,
877-887.
Ao, P., Hawthorne, W., Vicaretti, M., Fletcher, J.
(2000). Verapamil reduces intimal hyperplasia in
a sheep carotid artery patch graft model. ANZ
Journal of Surgery, 70(1), 64-67.