Publications for Sue Firth
Publications for Sue Firth
2015
Devis, D., Firth, S., Liang, Z., Byrne, M. (2015).
Dosage sensitivity of RPL9 and concerted
evolution of ribosomal protein genes in plants.
Frontiers in Plant Science, 6(Article 1102), 1-12.
<a
href="http://dx.doi.org/10.3389/fpls.2015.01102"
>[More Information]</a>
Pon, C., Firth, S., Baxter, R. (2015). Involvement
of insulin-like growth factor binding protein-3 in
peroxisome proliferator-activated receptor
gamma-mediated inhibition of breast cancer cell
growth. Molecular And Cellular Endocrinology,
399, 354-361. <a
href="http://dx.doi.org/10.1016/j.mce.2014.10.02
3">[More Information]</a>
2014
Johnson, M., Firth, S. (2014). IGFBP-3: A cell
fate pivot in cancer and disease. Growth
Hormone and IGF Research, 24(5), 164-173. <a
href="http://dx.doi.org/10.1016/j.ghir.2014.04.00
7">[More Information]</a>
2013
Grkovic, S., O'Reilly, V., Han, S., Hong, M.,
Baxter, R., Firth, S. (2013). IGFBP-3 binds
GRP78, stimulates autophagy and promotes the
survival of breast cancer cells exposed to adverse
microenvironments. Oncogene, 32(19),
2412-2420. <a
href="http://dx.doi.org/10.1038/onc.2012.264">[
More Information]</a>
2012
de Silva, H., Firth, S., Twigg, S., Baxter, R.
(2012). Interaction Between IGF Binding
Protein-3 and TGFb in in the Regulation of
Adipocyte Differentiation. Endocrinology,
153(10), 4799-4807. <a
href="http://dx.doi.org/10.1210/en.2011-1444">[
More Information]</a>
Jarajapu, Y., Cai, J., Yan, Y., Calzi, S.,
Kielczewski, J., Hu, P., Shaw, L., Firth, S.,
Chan-Ling, T., Boulton, M., Baxter, R., et al
(2012). Protection of Blood Retinal Barrier and
Systemic Vasculature by Insulin-Like Growth
Factor Binding Protein-3. PloS One, 7(7), 1-16.
<a
href="http://dx.doi.org/10.1371/journal.pone.003
9398">[More Information]</a>
2011
Firth, S., Yan, X., Baxter, R. (2011). D440N
Mutation in the Acid-Labile Subunit of
Insulin-Like Growth Factor Complexes Inhibits
Secretion and Complex Formation. Molecular
Endocrinology, 25(2), 307-314. <a
href="http://dx.doi.org/10.1210/me.2010-0295">
[More Information]</a>
Kielczewski, J., Calzi, S., Shaw, L., Cai, J., Qi,
X., Ruan, Q., Wu, L., Liu, L., Hu, P., Chan-Ling,
T., Firth, S., Baxter, R., et al (2011). Free
insulin-like growth factor binding protein-3
(IGFBP-3) reduces retinal vascular permeability
in association with a reduction of acid
sphingomyelinase (ASMase). Investigative
Ophthalmology and Visual Science, 52(11),
8278-8286. <a
href="http://dx.doi.org/10.1167/iovs.11-8167">[
More Information]</a>
2010
Lin, Z., Natesan, V., Shi, H., Hamik, A.,
Kawanami, D., Hao, C., Mahabaleshwar, G.,
Wang, W., Jin, Z., Atkins, G., Firth, S., et al
(2010). A novel role of CCN3 in regulating
endothelial inflammation. Journal of Cell
Communication and Signaling, 4, 141-153. <a
href="http://dx.doi.org/10.1007/s12079-010-009
5-x">[More Information]</a>
Yan, X., Baxter, R., Firth, S. (2010).
Involvement of pregnancy-associated plasma
protein-A2 in insulin-like growth factor (IGF)
binding protein-5 proteolysis during pregnancy:
a potential mechanism for increasing IGF
bioavailability. Journal of Clinical
Endocrinology and Metabolism, 95(3),
1412-1420. <a
href="http://dx.doi.org/10.1210/jc.2009-2277">[
More Information]</a>
2009
Yan, X., Payet, L., Baxter, R., Firth, S. (2009).
Activity of human pregnancy insulin-like growth
factor binding protein-3: determination by
reconstituting recombinant complexes.
Endocrinology, 150(11), 4968-4976. <a
href="http://dx.doi.org/10.1210/en.2009-0090">[
More Information]</a>
2007
Schedlich, L., Graham, L., O'Han, M.,
Muthukaruppan, A., Yan, X., Firth, S., Baxter, R.
(2007). Molecular basis of the interaction
between IGFBP-3 and retinoid X receptor: Role
in modulation of RAR-signaling. Archives of
Biochemistry and Biophysics, 465(2), 359-369.
<a
href="http://dx.doi.org/10.1016/j.abb.2007.06.01
3">[More Information]</a>
Graham, M., Kilby, D., Firth, S., Robinson, P.,
Baxter, R. (2007). The in vivo phosphorylation
and glycosylation of human insulin-like growth
factor binding protein-5. Molecular and Cellular
Proteomics, 6(8), 1392-1405. <a
Publications for Sue Firth
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17496250">[More Information]</a>
2006
Fukunaga-Kalabis, M., Martinez, G., Liu, Z.,
Kalabis, J., Mrass, P., Planque, N., Firth, S.,
Perbal, B., Herlyn, M., Weninger, W. (2006).
CCN3 controls 3D spatial localization of
melanocytes in the human skin through DDR1.
The Journal of Cell Biology, 175(4), 563-569. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17101694">[More Information]</a>
Santer, F., Bacher, N., Moser, B., Morandell, D.,
Ressler, S., Firth, S., Spoden, G., Sergi, C.,
Baxter, R., Jansen-Durr, P., et al (2006). Nuclear
insulin-like growth factor binding protein-3
induces apoptosis and is targeted to
ubiquitin/proteasome-dependent proteolysis.
Cancer Research, 66(6), 3024-3033. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=16540651">[More Information]</a>
Yan, X., Baxter, R., Perbal, B., Firth, S. (2006).
The aminoterminal insulin-like growth factor
(IGF) binding domain of IGF binding protein-3
cannot be functionally substituted by the
structurally homologous domain of CCN3.
Endocrinology, 147(11), 5268-5274. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=16935848">[More Information]</a>
2005
Chan, S., Twigg, S., Firth, S., Baxter, R. (2005).
Insulin-like growth factor binding protein-3 leads
to insulin resistance in adipocytes. Journal of
Clinical Endocrinology and Metabolism, 90(12),
6588-6595. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=16189260">[More Information]</a>
2004
Butt, A., Martin, J., Dickson, K., McDougall, F.,
Firth, S., Baxter, R. (2004). Insulin-Like Growth
Factor Binding Protein-3 Expression Is
Associated With Growth Stimulation Of T47D
Human Breast Cancer Cells: The Role Of
Altered Epidermal Growth Factor Signaling.
Journal of Clinical Endocrinology and
Metabolism, 89(4), 1950-1956.
Yan, X., Forbes, B., McNeil, K., Baxter, R.,
Firth, S. (2004). Role Of N- And C-Terminal
Residues Of Insulin-Like Growth Factor
(IGF)-Binding Protein-3 In Regulating IGF
Complex Formation And Receptor Activation.
Journal of Biological Chemistry, 279(51),
53232-53240.
Payet, L., Firth, S., Baxter, R. (2004). The Role
Of The Acid-Labile Subunit In Regulating
Insulin-Like Growth Factor Transport Across
Human Umbilical Vein Endothelial Cell
Monolayers. Journal of Clinical Endocrinology
and Metabolism, 89(5), 2382-2389.
Firth, S., Scott, C. (2004). The Role Of The
M6P/Igf-Ii Receptor In Cancer: Tumor
Suppression Or Garbage Disposal? Hormone
And Metabolic Research, 36(5), 261-271.
2003
Payet, L., Wang, X., Baxter, R., Firth, S. (2003).
Amino-and carboxyl-terminal fragments of
insulin-like growth factor (IGF) binding
protein-3 cooperate to bind IGFs with high
affinity and inhibit IGF receptor interactions.
Endocrinology, 144(7), 2797-2806.
Kricker, J., Towne, C., Firth, S., Herington, A.,
Upton, Z. (2003). Structural and functional
evidence for the interaction of insulin-like
growth factors (IGFs) and IGF binding proteins
with vitronectin. Endocrinology, 144(7),
2807-2815.
2002
Firth, S., Baxter, R. (2002). Cellular Actions of
the Insulin-like Growth Factor Binding Proteins.
Endocrine Reviews, 23(6), 824-854.
Butt, A., Fraley, K., Firth, S., Baxter, R. (2002).
IGF-Binding Protein-3-Induced Growth
Inhibition and Apoptosis Do Not Require Cell
Surface Binding and Nuclear Translocation in
Human Breast Cancer Cells. Endocrinology,
143(7), 2693-2699.
Firth, S., McDougall, F., McLachlan, A., Baxter,
R. (2002). Impaired Blockade of Insulin-Like
Growth Factor I (IGF-I)-Induced Hypoglycemia
by IGF Binding Protein-3 Analog with Reduced
Ternary Complex-Forming Ability.
Endocrinology, 143(5), 1669-1676.
O'Gorman, D., Weiss, J., Firth, S., Hettiaratchi,
A., Scott, C. (2002). Insulin-like Growth
Factor-II/Mannose 6-Phosphate Receptor
Overexpression Reduces Growth of
Choriocarcinoma Cells in Vitro and in Vivo.
Endocrinology, 143(11), 4287-4294.
Baxter, R., Meka, S., Firth, S. (2002). Molecular
Distribution of IGF Binding Protein-5 in Human
Serum. Journal of Clinical Endocrinology and
Metabolism, 87(1), 271-276.
Kong, S., Firth, S., Baxter, R., Delhanty, P.
(2002). Regulation of the acid-labile subunit in
sustained endotoxemia. American Journal of
Physiology: Endocrinology and Metabolism, ,
692-701.
Publications for Sue Firth
Fanayan, S., Firth, S., Baxter, R. (2002).
Signaling through the Smad Pathway by
Insulin-like Growth Factor-binding Protein-3 in
Breast Cancer Cells: Relationship to
transforming growth factor -β1 signaling.
Journal of Biological Chemistry, 277(9),
7255-7261.
2001
Firth, S., Baxter, R., Galanis, M., Bond,, J.,
Nathanielsz, A., Kortt, A., Hudson,, P. (2001).
Ligand-binding characteristics of recombinant
amino-and carboxyl-terminal fragments of
human insulin-like growth factor-binding
protein-3. Journal of Endocrinology, 169,
123-133.
Firth, S., Baxter, R., Clemmons,, D. (2001).
Mutagenesis of basic amino acids in the
carboxyl-terminal region of insulin-like growth
factor binding protein-5 affects acid-labile
subunit binding. Endocrinology, 142(5),
2147-2150.