Publications for Carl Feng
2016
Stifter, S., Bhattacharyya, N., Pillay, R., Florido,
M., Triccas, J., Britton, W., Feng, C. (2016).
Functional Interplay between Type I and II
Interferons Is Essential to Limit Influenza A
Virus-Induced Tissue Inflammation. PLoS
Pathogens , 12(1), 1-20. <a href="http://dx.doi.org/10.1371/journal.ppat.100
5378">[More Information]</a>
2015
Jankovic, D., Feng, C. (2015). CD4(+) T Cell
Differentiation in Infection: Amendments to the
Th1/Th2 Axiom. Frontiers in Immunology , 6,
198. <a href="http://dx.doi.org/10.3389/fimmu.2015.001
98">[More Information]</a>
Stifter, S., Feng, C. (2015). Interfering with immunity: detrimental role of type I IFNs during infection. The Journal of Immunology , 194(6),
2455-2465. <a href="http://dx.doi.org/10.4049/jimmunol.14027
94">[More Information]</a>
2014
Zhang, G., Zhou, B., Li, S., Yue, J., Yang, H.,
Yuxin, W., Zhan, S., Wang, W., Liao, M.,
Zhang, M., Feng, C., et al (2014). Allele-specific induction of IL-1β expression by C/EBPβ and
PU.1 contributes to increased tuberculosis susceptibility. PLoS Pathogens , 10(10), 1-15. <a href="http://dx.doi.org/10.1371/journal.ppat.100
4426">[More Information]</a>
Cai, Y., Yang, Q., Tang, Y., Zhang, M., Liu, H.,
Zhang, G., Deng, Q., Huang, J., Gao, Z., Zhou,
B., Feng, C., et al (2014). Increased complement
C1q level marks active disease in human tuberculosis. PloS One , 9(3), 1-11. <a href="http://dx.doi.org/10.1371/journal.pone.009
2340">[More Information]</a>
Stifter, S., Coleman, M., Feng, C. (2014).
Regulation of Host Response to Mycobacteria by
Type I Interferons. In Dane Parker (Eds.),
Bacterial Activation of Type I Interferons , (pp.
109-124). Cham, Switzerland: Springer.
2013
Shenderov, K., Barber, D., Mayer-Barber, K.,
Gurcha, S., Jankovic, D., Feng, C., Oland, S.,
Hieny, S., Caspar, P., Yamasaki, S., et al (2013).
Cord factor and peptidoglycan recapitulate the
Th17-promoting adjuvant activity of mycobacteria through mincle/CARD9 signaling and the inflammasome. The Journal of
Immunology , 190(11), 5722-5730. <a href="http://dx.doi.org/10.4049/jimmunol.12033
43">[More Information]</a>
Publications for Carl Feng
2012
Zhang, G., Zhou, B., Wang, W., Zhang, M.,
Zhao, Y., Wang, Z., Yang, L., Zhai, J., Feng, G.,
Wang, J., et al (2012). A functional single-nucleotide polymorphism in the promoter of the gene encoding interleukin 6 is associated with susceptibility to tuberculosis. The Journal of Infectious Diseases , 205(11), 1697-1704. <a href="http://dx.doi.org/10.1093/infdis/jis266">[
More Information]</a>
Klionsky, D., Abdalla, F., Abeliovich, H.,
Abraham, R., Acevedo-Arozena, A., Adeli, K.,
Agholme, L., Agnello, M., Agostinis, P.,
Aguirre-Ghiso, J., Bendall, L., Feng, C., Sidhu,
S., Xia, P., et al (2012). Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy , 8(4), 445-544. <a href="http://dx.doi.org/10.4161/auto.19496">[M ore Information]</a>
Vazquez, N., Rekka, S., Gliozzi, M., Feng, C.,
Amarnath, S., Orenstein, J., Wahl, S. (2012).
Modulation of Innate Host Factors by
Mycobacterium avium Complex in Human
Macrophages Includes Interleukin 17. The
Journal of Infectious Diseases , 206(8),
1206-1217. <a href="http://dx.doi.org/10.1093/infdis/jis492">[
More Information]</a>
2011
Barber, D., Mayer-Barber, K., Feng, C., Sharpe,
A., Sher, A. (2011). CD4 T cells promote rather than control tuberculosis in the absence of
PD-1-mediated inhibition. The Journal of
Immunology , 186(3), 1598-1607. <a href="http://dx.doi.org/10.4049/jimmunol.10033
04">[More Information]</a>
Triccas, J., Winter, N., Feng, C., West, N.
(2011). Immunity to Mycobacterium tuberculosis. Clinical & Developmental
Immunology , 2011, 406549-406549. <a href="http://dx.doi.org/10.1155/2011/406549">[
More Information]</a>
Mayer-Barber, K., Andrade, B., Barber, D.,
Hieny, S., Feng, C., Caspar, P., Oland, S.,
Gordon, S., Sher, A. (2011). Innate and adaptive interferons suppress IL-1(alpha) and IL-1(beta) production by distinct pulmonary myeloid subsets during Mycobacterium tuberculosis infection. Immunity , 35(6), 1023-1034. <a href="http://dx.doi.org/10.1016/j.immuni.2011.1
2.002">[More Information]</a>
Egen, J., Rothfuchs, A., Feng, C., Horwitz, M.,
Sher, A., Germain, R. (2011). Intravital imaging reveals limited antigen presentation and T cell effector function in mycobacterial granulomas.
Immunity , 34(5), 807-819. <a href="http://dx.doi.org/10.1016/j.immuni.2011.0

Publications for Carl Feng
3.022">[More Information]</a>
Hunn, J., Feng, C., Sher, A., Howard, J. (2011).
The immunity-related GTPases in mammals: a fast-evolving cell-autonomous resistance system against intracellular pathogens. Mammalian
Genome , 22(1-2), 43-54. <a href="http://dx.doi.org/10.1007/s00335-010-929
3-3">[More Information]</a>
2010
Antonelli, L., Rothfuchs, A., Goncalves, R.,
Roffe, E., Cheever, A., Bafica, A., Salazar, A.,
Feng, C., Sher, A. (2010). Intranasal Poly-IC treatment exacerbates tuberculosis in mice through the pulmonary recruitment of a pathogen-permissive monocyte/macrophage population. Journal of Clinical Investigation ,
120(5), 1674-1682. <a href="http://dx.doi.org/10.1172/JCI40817">[Mor e Information]</a>
Feng, C., Sher, A. (2010). Parasites paralyze cellular host defense system to promote virulence. Cell Host and Microbe , 8(6), 463-464.
<a href="http://dx.doi.org/10.1016/j.chom.2010.11.
012">[More Information]</a>
Feng, C., Wilson, M., Barber, D., Yarovinsky,
F., Cheever, A., Sher, A., Griggs, M., Collins,
M., Fouser, L., Wynn, T. (2010). Redundant and pathogenic roles for IL-22 in mycobacterial, protozoan, and helminth infections. The Journal of Immunology , 184(8), 4378-4390. <a href="http://dx.doi.org/10.4049/jimmunol.09034
16">[More Information]</a>
2009
Henry, S., Daniell, X., Burroughs, A., Indaram,
M., Howell, D., Coers, J., Starnbach, M., Hunn,
J., Howard, J., Feng, C., et al (2009). Balance of
Irgm protein activities determines
IFN-gamma-induced host defense. Journal of
Leukocyte Biology , 85(5), 877-885. <a href="http://dx.doi.org/10.1189/jlb.1008599">[
More Information]</a>
Rothfuchs, A., Egen, J., Feng, C., Antonelli, L.,
Bafica, A., Winter, N., Locksley, R., Sher, A.
(2009). In situ IL-12/23p40 production during mycobacterial infection is sustained by
CD11bhigh dendritic cells localized in tissue sites distinct from those harboring bacilli. The
Journal of Immunology , 182(11), 6915-6925. <a href="http://dx.doi.org/10.4049/jimmunol.09000
74">[More Information]</a>
Feng, C., Zheng, L., Lenardo, M., Sher, A.
(2009). Interferon-inducible immunity-related
GTPase Irgm1 regulates IFN gamma-dependent host defense, lymphocyte survival and autophagy. Autophagy , 5(2), 232-234. <a href="http://dx.doi.org/10.4161/auto.5.2.7445">[
More Information]</a>
Steinfelder, S., Andersen, J., Cannons, J., Feng,
C., Joshi, M., Dwyer, D., Caspar, P.,
Schwartzberg, P., Sher, A., Jankovic, D. (2009).
The major component in schistosome eggs responsible for conditioning dendritic cells for
Th2 polarization is a T2 ribonuclease (omega-1).
The Journal of Experimental Medicine , 206(8),
1681-1690. <a href="http://dx.doi.org/10.1084/jem.20082462">
[More Information]</a>
2008
West, N., Wozniak, T., Valenzuela, J., Feng, C.,
Sher, A., Ribeiro, J., Britton, W. (2008).
Immunological diversity within a family of cutinase-like proteins of Mycobacterium tuberculosis. Vaccine , 26(31), 3853-3859. <a href="http://dx.doi.org/10.1016/j.vaccine.2008.0
5.007">[More Information]</a>
Alter-Koltunoff, M., Goren, S., Nousbeck, J.,
Feng, C., Sher, A., Ozato, K., Azriel, A., Levi, B.
(2008). Innate immunity to intraphagosomal pathogens is mediated by interferon regulatory factor 8 (IRF-8) that stimulates the expression of macrophage-specific Nramp1 through antagonizing repression by c-Myc. Journal of
Biological Chemistry , 283(5), 2724-2733. <a href="http://dx.doi.org/10.1074/jbc.M707704200
">[More Information]</a>
Egen, J., Rothfuchs, A., Feng, C., Winter, N.,
Sher, A., Germain, R. (2008). Macrophage and T cell dynamics during the development and disintegration of mycobacterial granulomas.
Immunity , 28(2), 271-284. <a href="http://dx.doi.org/10.1016/j.immuni.2007.1
2.010">[More Information]</a>
Feng, C., Zheng, L., Jankovic, D., Bafica, A.,
Cannons, J., Watford, W., Chaussabel, D.,
Hieny, S., Caspar, P., Schwartzberg, P., et al
(2008). The immunity-related GTPase Irgm1 promotes the expansion of activated CD4+ T cell populations by preventing interferon-gamma-induced cell death. Nature
Immunology , 9(11), 1279-1287. <a href="http://dx.doi.org/10.1038/ni.1653">[More
Information]</a>
Feng, C., Weksberg, D., Taylor, G., Sher, A.,
Goodell, M. (2008). The p47 GTPase Lrg-47
(Irgm1) links host defense and hematopoietic stem cell proliferation. Cell Stem Cell , 2(1),
83-89. <a href="http://dx.doi.org/10.1016/j.stem.2007.10.0
07">[More Information]</a>
2007
Taylor, G., Feng, C., Sher, A. (2007). Control of
IFN-gamma-mediated host resistance to intracellular pathogens by immunity-related

GTPases (p47 GTPases). Microbes and
Infection , 9(14-15), 1644-1651. <a href="http://dx.doi.org/10.1016/j.micinf.2007.09.
004">[More Information]</a>
Jankovic, D., Kullberg, M., Feng, C., Goldszmid,
R., Collazo, C., Wilson, M., Wynn, T.,
Kamanaka, M. (2007). Conventional
T-bet(+)Foxp3(-) Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection. The Journal of
Experimental Medicine , 204(2), 273-283. <a href="http://dx.doi.org/10.1084/jem.20062175">
[More Information]</a>
Rothfuchs, A., Bafica, A., Feng, C., Egen, J.,
Williams, D., Brown, G., Sher, A. (2007).
Dectin-1 interaction with Mycobacterium tuberculosis leads to enhanced IL-12p40 production by splenic dendritic cells. The
Journal of Immunology , 179(6), 3463-3471. <a href="http://dx.doi.org/10.4049/​jimmunol.179
.6.3463">[More Information]</a>
Goldszmid, R., Bafica, A., Jankovic, D., Feng,
C., Caspar, P., Winkler-Pickett, R., Trinchieri,
G., Sher, A. (2007). TAP-1 indirectly regulates
CD4+ T cell priming in Toxoplasma gondii infection by controlling NK cell IFN-gamma production. The Journal of Experimental
Medicine , 204(11), 2591-2602. <a href="http://dx.doi.org/10.1084/jem.20070634">
[More Information]</a>
Bafica, A., Feng, C., Santiago, H., Aliberti, J.,
Cheever, A., Thomas, K., Taylor, G., Vogel, S.,
Sher, A. (2007). The IFN-inducible GTPase
LRG47 (Irgm1) negatively regulates
TLR4-triggered proinflammatory cytokine production and prevents endotoxemia. The
Journal of Immunology , 179(8), 5514-5522. <a href="http://dx.doi.org/10.4049/​jimmunol.179
.8.5514">[More Information]</a>
2006
Kullberg, M., Jankovic, D., Feng, C., Hue, S.,
Gorelick, P., McKenzie, B., Cua, D., Powrie, F.,
Cheever, A., Maloy, K., et al (2006). IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis. The Journal of
Experimental Medicine , 203(11), 2485-2494. <a href="http://dx.doi.org/10.1084/jem.20061082">
[More Information]</a>
Reiman, R., Thompson, R., Feng, C., Hari, D.,
Knight, R., Cheever, A., Rosenberg, H., Wynn,
T. (2006). Interleukin-5 (IL-5) augments the progression of liver fibrosis by regulating IL_13 activity. Infection and Immunity , 74(3),
1471-1479. <a href="http://dx.doi.org/10.1128/IAI.74.3.1471-1
479.2006">[More Information]</a>
Feng, C., Kaviratne, M., Rothfuchs, A., Cheever,
Publications for Carl Feng
A., Hieny, S., Young, H., Wynn, T., Sher, A.
(2006). NK cell-derived IFN-gamma differentially regulates innate resistance and neutrophil response in T cell-deficient hosts infected with Mycobacterium tuberculosis. The
Journal of Immunology , 177(10), 7086-7093. <a href="http://dx.doi.org/10.4049/​jimmunol.177
.10.7086">[More Information]</a>
2001
Feng, C., Britton, W., Demangel, C., Kamath,
A., Macdonald, M. (2001). Dendritic cells infected with Mycobacterium bovis bacillus
Calmette Guerin activate CD8+ T cells with specificity for a novel mycobacterial epitope.
International Immunology , 13, 451-458.
Feng, C., Britton, W., Blanchard,, T., Smith, G.,
Hill, A. (2001). Induction of CD8+
T-lymphocyte responses to a secreted antigen of
Mycobacterium tuberculosis by an attenuated vaccine virus. Immunology and Cell Biology , 79,
569-575.
Feng, C., Umaimainthan, P., Britton, W.,
Demangel, C., Spratt, J., Malin, A. (2001).
Priming by DNA immunization augments protective efficacy of Mycobacterium bovis bacille Calmette-Guerin against tuberculosis.
Infection and Immunity , 69, 4174-4176.
Umaimainthan, P., Feng, C., Britton, W.,
Demangel, C., Heath, A., Bean, A. (2001).
Stimulation of dendritic cells via CD40 enhances immune responses to Mycobacterium tuberculosis infection. Infection and Immunity ,
69, 2456-2461.