Publications for Mary Collins
Publications for Mary Collins
2016
Lee, H., Absalom, N., Hanrahan, J., van
Nieuwenhuijzen, P., Ahring, J., Collins, M.
(2016). A pharmacological characterization of
GABA, THIP and DS2 at binary ?4?3 and ?3?
receptors: GABA activates ?3? receptors via the
?3(+)?(-) interface. Brain Research, 1644,
222-230. <a
href="http://dx.doi.org/10.1016/j.brainres.2016.0
5.019">[More Information]</a>
Khan, I., Karim, N., Ahmad, W., Abdelhalim,
A., Collins, M. (2016). GABA-A Receptor
Modulation and Anticonvulsant, Anxiolytic, and
Antidepressant Activities of Constituents from
Artemisia indica Linn. Evidence-Based
Complementary and Alternative Medicine, 2016,
1-12. <a
href="http://dx.doi.org/10.1155/2016/1215393">
[More Information]</a>
Hartiadi, L., Ahring, J., Chebib, M., Absalom, N.
(2016). High and low GABA sensitivity
alpha4beta2delta GABAA receptors are
expressed in Xenopus laevis oocytes with
divergent stoichiometries. Biochemical
Pharmacology, 103, 98-108. <a
href="http://dx.doi.org/10.1016/j.bcp.2015.12.02
1">[More Information]</a>
2015
Carland, J., Yamamoto, I., Hanrahan, J.,
Abdel-Halim, H., Lewis, T., Absalom, N.,
Chebib, M. (2015). A Hydrophobic Area of the
GABA p1 Receptor Containing Phenylalanine
124 Influences Both Receptor Activation and
Deactivation. Journal of Molecular
Neuroscience, 55(2), 305-313. <a
href="http://dx.doi.org/10.1007/s12031-014-032
2-7">[More Information]</a>
et al (2015). Engineered alpha4beta2 nicotinic
acetylcholine receptors as models for measuring
agonist binding and effect at the orthosteric
low-affinity alpha4-alpha4 interface.
Neuropharmacology, 92, 135-145. <a
href="http://dx.doi.org/10.1016/j.neuropharm.20
14.12.035">[More Information]</a>
Karim, N., Irshad, S., Khan, I., Mohammad, A.,
Anis, I., Shah, M., Khan, I., Chebib, M. (2015).
GABAA receptor modulation and
neuropharmacological activities of viscosine
isolated from Dodonaea viscosa (Linn).
Pharmacology, Biochemistry and Behavior, 136,
64-72. <a
href="http://dx.doi.org/10.1016/j.pbb.2015.07.00
6">[More Information]</a>
Neumann, S., Shields, N., Balle, T., Chebib, M.,
Clarkson, A. (2015). Innate Immunity and
Inflammation Post-Stroke: An alpha7-Nicotinic
Agonist Perspective. International Journal of
Molecular Sciences, 16(12), 29029-29046. <a
href="http://dx.doi.org/10.3390/ijms161226141"
>[More Information]</a>
Hanrahan, J., Chebib, M., Johnston, G. (2015).
Interactions of flavonoids with ionotropic GABA
receptors. Advances in Pharmacology, 72,
189-200. <a
href="http://dx.doi.org/10.1016/bs.apha.2014.10.
007">[More Information]</a>
Bowen, M., Peters, S., Absalom, N., Chebib, M.,
Neumann, I., McGregor, I. (2015). Oxytocin
prevents ethanol actions at δ subunitcontaining
GABAA receptors and attenuates ethanolinduced
motor impairment in rats. Proceedings of the
National Academy of Sciences of the United
States of America (PNAS), 112(10), 3104-3109.
<a
href="http://dx.doi.org/10.1073/pnas.141690011
2">[More Information]</a>
Constituents from Rosmarinus Officinalis.
Journal of Pharmacy and Pharmaceutical
Sciences, 18(4), 448-459.
Hellyer, S., Indurthi Venkata, D., Balle, T.,
Runder-Varga, V., Selwood, A., Tyndall, J.,
Chebib, M., Rhodes, L., Kerr, S. (2015).
Pinnatoxins E, F and G target multiple nicotinic
receptor subtypes. Journal of Neurochemistry,
135(3), 479-491. <a
href="http://dx.doi.org/10.1111/jnc.13245">[Mo
re Information]</a>
Naffaa, M., Chebib, M., Hibbs, D., Hanrahan, J.
(2015). Comparison of templates for homology
model of rho1 GABAC receptors: More insights
to the orthosteric binding site's structure and
functionality. Journal of Molecular Graphics
and Modelling, 62, 43-55. <a
href="http://dx.doi.org/10.1016/j.jmgm.2015.09.
002">[More Information]</a>
Absalom, N., Yamamoto, I., O'Hagan, D.,
Hunter, L., Collins, M. (2015). Probing the Mode
of Neurotransmitter Binding to GABA Receptors
Using Selectively Fluorinated GABA Analogues.
Australian Journal of Chemistry, 68(1), 23-30.
<a
href="http://dx.doi.org/10.1071/CH14456">[Mor
e Information]</a>
Ahring, J., Olsen, J., Nielsen, E., Peters, D.,
Pedersen, M., Rohde, L., Kastrup, J., Shahsavar,
A., Indurthi Venkata, D., Chebib, M., Balle, T.,
Chua, H., Absalom, N., Hanrahan, J., Viswas, R.,
Chebib, M. (2015). The Direct Actions of
GABA, 2’-Methoxy-6-Methylflavone and
Abdelhalim, A., Karim, N., Chebib, M., Aburjai,
T., Khan, I., Johnston, G., Hanrahan, J. (2015).
Antidepressant, Anxiolytic and Antinociceptive
Activities of
Publications for Mary Collins
General Anaesthetics at β3γ2L GABAA
Receptors: Evidence for Receptors with
Different Subunit Stoichiometries. PloS One,
10(10), 1-19. <a
href="http://dx.doi.org/10.1371/journal.pone.014
1359">[More Information]</a>
Gallagher, R., Chebib, M., Balle, T., McLeod,
M. (2015). Thiol-Reactive Analogues of
Galanthamine, Codeine, and Morphine as
Potential Probes to Interrogate Allosteric
Binding within Nicotinic Acetylcholine
Receptors. Australian Journal of Chemistry,
68(12), 1834-1841. <a
href="http://dx.doi.org/10.1071/CH15475">[Mor
e Information]</a>
2014
Beltrán González, A., Pomata, P., Goutman, J.,
Gasulla, J., Chebib, M., Calvo, D. (2014).
Benzodiazepine modulation of homomeric
GABAAp1 receptors: Differential effects of
diazepam and 4'-chlorodiazepam. European
Journal of Pharmacology, 743, 24-30. <a
href="http://dx.doi.org/10.1016/j.ejphar.2014.09.
017">[More Information]</a>
Abdelhalim, A., Chebib, M., Aburjai, T.,
Johnston, G., Hanrahan, J. (2014). GABAA
Receptor Modulation by Compounds Isolated
from Salvia triloba L. Advances in Biological
Chemistry, 4(2), 148-159. <a
href="http://dx.doi.org/10.4236/abc.2014.42019"
>[More Information]</a>
Blednov, Y., Benavidez, J., Black, M., Leiter, C.,
Osterndoff-Kahanek, E., Johnson, D., Borghese,
C., Hanrahan, J., Johnston, G., Chebib, M., et al
(2014). GABAA Receptors Containing p1
Subunits Contribute to In Vivo Effects of
Ethanol in Mice. PloS One, 9(1), 1-16. <a
href="http://dx.doi.org/10.1371/journal.pone.008
5525">[More Information]</a>
Hall, B., Karim, N., Chebib, M., Johnston, G.,
Hanrahan, J. (2014). Modulation of Ionotropic
GABA Receptors by 6-Methoxyflavanone and
6-Methoxyflavone. Neurochemical Research, 39,
1068-1078. <a
href="http://dx.doi.org/10.1007/s11064-013-115
7-2">[More Information]</a>
Indurthi Venkata, D., Pera, E., Kim, H., Chu, C.,
McLeod, M., McIntosh, J., Absalom, N., Chebib,
M. (2014). Presence of multiple binding sites on
Alpha9Alpha10 nAChR receptors alludes to
stoichiometric-dependent action of the Alpha conotoxin, Vc1.1. Biochemical Pharmacology,
89(1), 131-140. <a
href="http://dx.doi.org/10.1016/j.bcp.2014.02.00
2">[More Information]</a>
van Nieuwenhuijzen, P., McGregor, I., Chebib,
M., Hunt, G. (2014). Regional Fos-expression
induced by γ-hydroxybutyrate (GHB):
Comparison with γ-butyrolactone (GBL) and
effects of co-administration of the GABAB
antagonist SCH 50911 and putative GHB
antagonist NCS-382. Neuroscience, 277,
700-715. <a
href="http://dx.doi.org/10.1016/j.neuroscience.2
014.07.056">[More Information]</a>
Clarkson, A., Chebib, M. (2014). The Role of
Peri-synaptic GABA Receptors After Stroke. In
Adam C Errington, Giuseppe Di Giovanni,
Vincenzo Crunelli (Eds.), Extrasynaptic GABAA
Receptors, (pp. 179-205). New York: Springer
Science+Business Media.
2013
Absalom, N., Quek, G., Lewis, T., Qudah, T.,
von Arenstorff, I., Ambrus, J., Harpsøe, K.,
Karim, N., Balle, T., McLeod, M., Chebib, M.
(2013). Covalent trapping of methyllycaconitine
at the alpha4-alpha4 interface of the apha4beta2
nicotinic acetylcholine receptor: antagonist
binding site and mode of receptor inhibition
revealed. Journal of Biological Chemistry,
288(37), 26521-26532. <a
href="http://dx.doi.org/10.1074/jbc.M113.47505
3">[More Information]</a>
Gavande, N., Kim, H., Doddareddy, M.,
Johnston, G., Chebib, M., Hanrahan, J. (2013).
Design, synthesis, and pharmacological
evaluation of fluorescent and biotinylated
antagonists of P1 GABA(c) receptors. ACS
Medicinal Chemistry Letters, 4(4), 402-407. <a
href="http://dx.doi.org/10.1021/ml300476v">[M
ore Information]</a>
Karim, N., Wellendorph, P., Absalom, N.,
Johnston, G., Hanrahan, J., Chebib, M. (2013).
Potency of gaba at human recombinant gaba
alpha receptors expressed in xenopus oocytes: a
mini review. Amino Acids, 44(4), 1139-1149. <a
href="http://dx.doi.org/10.1007/s00726-012-145
6-y">[More Information]</a>
Locock, K., Yamamoto, I., Tran, P., Hanrahan,
J., Chebib, M., Johnston, G., Allan, R. (2013).
γ-Aminobutyric Acid(C) (GABAC) Selective
Antagonists Derived from the Bioisosteric
Modification of
4-Aminocyclopent-1-enecarboxylic Acid:
Amides and Hydroxamates. Journal of Medicinal
Chemistry, 56(13), 5626-5630. <a
href="http://dx.doi.org/10.1021/jm4006548">[M
ore Information]</a>
2012
Pan, Y., Gerasimov, M., Kvist, T., Wellendorph,
P., Madsen, K., Pera, E., Lee, H., Schousboe, A.,
Chebib, M., Brauner-Osborne, H., et al (2012).
(1S,
3S)-3-Amino-4-difluoromethylenyl-1-cyclopenta
Publications for Mary Collins
noic Acid (CPP-115), a Potent
gamma-Aminobutyric Acid Aminotransferase
Inactivator for the Treatment of Cocaine
Addiction. Journal of Medicinal Chemistry,
55(1), 357-366. <a
href="http://dx.doi.org/10.1021/jm201231w">[
More Information]</a>
Absalom, N., Eghorn, L., Villumsen, I., Karim,
N., Bay, T., Olsen, J., Knudsen, G.,
Brauner-Osborne, H., Fr&oslash;lund, B.,
Clausen, R., Chebib, M., et al (2012).
(alpha)4(beta)(delta) GABAA receptors are
high-affinity targets for gamma-hydroxybutyric
acid (GHB). Proceedings of the National
Academy of Sciences of the United States of
America (PNAS), 109(33), 13404-13409. <a
href="http://dx.doi.org/10.1073/pnas.120437610
9">[More Information]</a>
Karim, N., Curmi, J., Gavande, N., Johnston, G.,
Hanrahan, J., Tierney, L., Chebib, M. (2012).
2'-Methoxy-6-methylflavone: A novel anxiolytic
and sedative with subtype selective activating
and modulating actions at GABA(A) receptors.
British Journal of Pharmacology, 165(4),
880-896. <a
href="http://dx.doi.org/10.1111/j.1476-5381.201
1.01604.x">[More Information]</a>
Beinat, C., Banister, S., Prehn, S., Doddareddy,
M., Hibbs, D., Sako, M., Chebib, M., Tran, T.,
Al-Muhtasib, N., Xiao, Y., Kassiou, M. (2012).
Consequences of linker length alteration of the
alpha7 nicotinic acetylcholine receptor (nAChR)
agonist, SEN12333. Bioorganic and Medicinal
Chemistry Letters: the tetrahedron journal for
research at the interface of chemistry and
biology, 22(7), 2380-2384. <a
href="http://dx.doi.org/10.1016/j.bmcl.2012.02.0
52">[More Information]</a>
Ambrus, J., Halliday, J., Kanizaj, N., Absalom,
N., Harpsøe, K., Balle, T., Chebib, M., McLeod,
M. (2012). Covalent attachment of antagonists to
the (alpha)7 nicotinic acetylcholine receptor:
synthesis and reactivity of substituted
maleimides. Chemical Communications, 48(53),
6699-6701. <a
href="http://dx.doi.org/10.1039/c2cc32442c">[
More Information]</a>
Flavan-3-ol esters: new agents for exploring
modulatory sites on GABAA receptors. British
Journal of Pharmacology, 165(4), 965-977. <a
href="http://dx.doi.org/10.1111/j.1476-5381.201
1.01615.x">[More Information]</a>
Cheng, Z., Chebib, M., Schmid, K. (2012).
Identification of GABA receptors in chick
cornea. Molecular Vision, 18, 1107-1114. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=22605922">[More Information]</a>
Karim, N., Wellendorph, P., Absalom, N., Bang,
L., Jensen, M., Hansen, M., Lee, H., Johnston,
G., Hanrahan, J., Chebib, M. (2012). Low
nanomolar GABA effects at extrasynaptic
a4b1/b3d GABAA receptor subtypes indicate a
different binding mode for GABA at these
receptors. Biochemical Pharmacology, 84(4),
549-557. <a
href="http://dx.doi.org/10.1016/j.bcp.2012.05.01
7">[More Information]</a>
Huang, S., Lewis, T., Lummis, S., Thompson,
A., Chebib, M., Johnston, G., Duke, R. (2012).
Mixed antagonistic effects of the ginkgolides at
recombinant human r1 GABAc receptors.
Neuropharmacology, 63(6), 1127-1139. <a
href="http://dx.doi.org/10.1016/j.neuropharm.20
12.06.067">[More Information]</a>
Yamamoto, I., Carland, J., Locock, K., Gavande,
N., Absalom, N., Hanrahan, J., Allan, R.,
Johnston, G., Chebib, M. (2012). Structurally
Diverse GABA Antagonists Interact Differently
with Open and Closed Conformational States of
the p1 Receptor. ACS Chemical Neuroscience,
3(4), 293-301. <a
href="http://dx.doi.org/10.1021/cn200121r">[M
ore Information]</a>
Yamamoto, I., Jordan, M., Gavande, N.,
Doddareddy, M., Chebib, M., Hunter, L. (2012).
The enantiomers of
syn-2,3-difluoro-4-aminobutyric acid elicit
opposite responses at the GABA(C) receptor.
Chemical Communications, 48(6), 829-831. <a
href="http://dx.doi.org/10.1039/c1cc15816c">[
More Information]</a>
2011
Yamamoto, I., Absalom, N., Carland, J.,
Doddareddy, M., Gavande, N., Johnston, G.,
Hanrahan, J., Chebib, M. (2012). Differentiating
Enantioselective Actions of GABOB: A Possible
Role for Threonine 244 in the Binding Site of
GABAC rho1 Receptors. ACS Chemical
Neuroscience, 3(9), 665-673. <a
href="http://dx.doi.org/10.1021/cn3000229">[M
ore Information]</a>
Xie, A., Yan, J., Yue, L., Feng, F., Mir, F.,
Abdel-Halim, H., Chebib, M., Le Breton, G.,
Standaert, R., Qian, H., et al (2011).
2-Aminoethyl Methylphosphonate, a Potent and
Rapidly Acting Antagonist of GABAA-p1
Receptors. Molecular Pharmacology, 80(6),
965-978. <a
href="http://dx.doi.org/10.1124/mol.111.071225
">[More Information]</a>
Fernandez, S., Karim, N., Mewett, K., Chebib,
M., Johnston, G., Hanrahan, J. (2012).
Karim, N., Gavande, N., Wellendorph, P.,
Johnston, G., Hanrahan, J., Chebib, M. (2011).
Publications for Mary Collins
3-Hydroxy-2'-methoxy-6-methylflavone: A
potent anxiolytic with a unique selectivity profile
at GABBA receptor subtypes. Biochemical
Pharmacology, 82(12), 1971-1983. <a
href="http://dx.doi.org/10.1016/j.bcp.2011.09.00
2">[More Information]</a>
Yamamoto, I., Deniau, G., Gavande, N., Chebib,
M., Johnston, G., O'Hagan, D. (2011). Agonist
responses of (R)- and
(S)-3-fluoro-??-aminobutyric acids suggest an
enantiomeric fold for GABA binding to
GABA(C) receptors. Chemical Communications,
47(28), 7956-7958. <a
href="http://dx.doi.org/10.1039/c1cc12141c">[
More Information]</a>
Wong, S., Chebib, M., Haqshenas, G., Loveland,
B., Gowans, E. (2011). Dengue virus PrM/M
proteins fail to show pH-dependent ion channel
activity in Xenopus oocytes. Virology, 412(1),
83-90. <a
href="http://dx.doi.org/10.1016/j.virol.2010.12.0
50">[More Information]</a>
Hanrahan, J., Chebib, M., Johnston, G. (2011).
Flavonoid modulation of GABA(A) receptors.
British Journal of Pharmacology, 163(2),
234-245. <a
href="http://dx.doi.org/10.1111/j.1476-5381.201
1.01228.x">[More Information]</a>
Loscalzo, L., Yow, T., Wasowski, C., Chebib,
M., Marder, M. (2011). Hesperidin induces
antinociceptive effect in mice and its aglicone,
hesperetin, binds to mu-opioid receptor and
inhibits GIRK1/2 currents. Pharmacology,
Biochemistry and Behavior, 99(3), 333-341. <a
href="http://dx.doi.org/10.1016/j.pbb.2011.05.01
8">[More Information]</a>
Gavande, N., Karim, N., Johnston, G., Hanrahan,
J., Chebib, M. (2011). Identification of
Benzopyran-4-one Derivatives (Isoflavones) as
Positive Modulators of GABAA Receptors.
ChemMedChem: chemistry enabling drug
discovery, 6(8), 1340-1346. <a
href="http://dx.doi.org/10.1002/cmdc.201100120
">[More Information]</a>
Ng, C., Kim, H., Gavande, N., Yamamoto, I.,
Kumar, R., Mewett, K., Johnston, G., Hanrahan,
J., Chebib, M. (2011). Medicinal Chemistry of p
GABAc Receptors. Future Medicinal Chemistry,
3(2), 197-209. <a
href="http://dx.doi.org/10.4155/FMC.10.286">[
More Information]</a>
Yow, T., Pera, E., Absalom, N., Heblinski, M.,
Johnston, G., Hanrahan, J., Chebib, M. (2011).
Naringin directly activates inwardly rectifying
potassium channels at an overlapping binding
site to tertiapin-Q. British Journal of
Pharmacology, 163(5), 1017-1033. <a
href="http://dx.doi.org/10.1111/j.1476-5381.201
1.01315.x">[More Information]</a>
Gavande, N., Yamamoto, I., Salam, N., Tu-Hoa,
A., Burden, P., Johnston, G., Hanrahan, J.,
Chebib, M. (2011). Novel Cyclic Phosphinic
Acids as GABAC F Receptor Antagonists:
Design, Synthesis, and Pharmacology. ACS
Medicinal Chemistry Letters, 2(1), 11-16. <a
href="http://dx.doi.org/10.1021/ml1001344">[M
ore Information]</a>
Cheng, Z., Chebib, M., Schmidt, K. (2011).
rho(1) GABA(C) receptors are expressed in
fibrous and cartilaginous layers of chick sclera
and located on sclera fibroblasts and
chondrocytes. Journal of Neurochemistry,
118(2), 281-287. <a
href="http://dx.doi.org/10.1111/j.1471-4159.201
1.07300.x">[More Information]</a>
2010
Quek, G., Lin, D., Halliday, J., Absalom, N.,
Ambrus, J., Thompson, A., Lochner, M.,
Lummis, S., McLeod, M., Chebib, M. (2010).
Identifying the Binding Site of Novel
Methyllycaconitine (MLA) Analogs at α4β2
Nicotinic Acetylcholine Receptors. ACS
Chemical Neuroscience, 1(12), 796-809. <a
href="http://dx.doi.org/10.1021/cn100073x">[M
ore Information]</a>
Gavande, N., Johnston, G., Hanrahan, J., Chebib,
M. (2010). Microwave-enhanced synthesis of
2,3,6-trisubstituted pyridazines: Application to
four-step synthesis of gabazine (SR-95531).
Organic and Biomolecular Chemistry, 8(18),
4131-4136. <a
href="http://dx.doi.org/10.1039/c0ob00004c">[
More Information]</a>
Johnston, G., Chebib, M., Hanrahan, J., Mewett,
K. (2010). Neurochemicals for the Investigation
of GABAc Receptors. Neurochemical Research,
35(12), 1970-1977. <a
href="http://dx.doi.org/10.1007/s11064-010-027
1-7">[More Information]</a>
Halliday, J., Chebib, M., McLeod, M. (2010).
Synthesis and biological evaluation of a new
family of constrained azabicyclic homocholine
analogues. Australian Journal of Chemistry,
63(5), 808-812. <a
href="http://dx.doi.org/10.1071/CH10024">[Mor
e Information]</a>
2009
McIntosh, J., Absalom, N., Chebib, M., Belen
Elgoyhen, A., Vincler, M. (2009). Alpha9
nicotinic acetylcholine receptors and the
treatment of pain. Biochemical Pharmacology,
78(7), 693-702. <a
href="http://dx.doi.org/10.1016/j.bcp.2009.05.02
0">[More Information]</a>
Publications for Mary Collins
Chebib, M., Gavande, N., Wong, K., Park, A.,
Premoli, I., Mewett, K., Allan, R., Duke, R.,
Johnston, G., Hanrahan, J. (2009). Guanidino
Acids Act as p1 GABAc Receptor Antagonists.
Neurochemical Research, 34(10), 1704-1711. <a
href="http://dx.doi.org/10.1007/s11064-009-996
8-x">[More Information]</a>
Chebib, M., Hanrahan, J., Johnston, G. (2009).
Neurologically-active Compounds (II). Patent
No. 2002364767.
Hanrahan, J., Johnston, G., Kumar, R., Chebib,
M. (2009). Neurologically-active Compounds
(III). Patent No. 1773740.
Chebib, M., Hinton, T., Schmid, K., Brinkworth,
D., Qian, H., Matos, S., Kim, H., Abdel-Halim,
H., Kumar, R., Johnston, G., Hanrahan, J.
(2009). Novel, potent and selective GABAC
antagonists inhibit myopia development and
facilitate learning and memory. Journal of
Pharmacology and Experimental Therapeutics,
328(2), 448-457. <a
href="http://dx.doi.org/10.1124/jpet.108.146464"
>[More Information]</a>
MacRaild, C., Illesinghe, J., vanLierop, B.,
Townsend, A., Chebib, M., Livett, B., Robinson,
A., Norton, R. (2009). Structure and Activity of
(2,8)-Dicarba-(3,12)-cystino alpha-ImI, an
alpha-Conotoxin Containing a Nonreducible
Cystine Analogue. Journal of Medicinal
Chemistry, 52(3), 755-762. <a
href="http://dx.doi.org/10.1021/jm8011504">[M
ore Information]</a>
Mewett, K., Fernandez, S., Pasricha, A., Pong,
A., Devenish, S., Hibbs, D., Chebib, M.,
Johnston, G., Hanrahan, J. (2009). Synthesis and
biological evaluation of flavan-3-ol derivatives
as positive modulators of GABAA receptors.
Bioorganic and Medicinal Chemistry, 17(20),
7156-7173. <a
href="http://dx.doi.org/10.1016/j.bmc.2009.08.0
62">[More Information]</a>
Fernandez, S., Nguyen, M., Yow, T., Chu, C.,
Johnston, G., Hanrahan, J., Chebib, M. (2009).
The flavonoid glycosides, myricitrin, gossypin
and naringin exert anxiolytic action in mice.
Neurochemical Research, 34(10), 1867-1875. <a
href="http://dx.doi.org/10.1007/s11064-009-996
9-9">[More Information]</a>
2008
Abdel-Halim, H., Hanrahan, J., Hibbs, D.,
Johnston, G., Chebib, M. (2008). A molecular
basis for agonist and antagonist actions at
GABA(C) receptors. Chemical Biology and
Drug Design (Print), 71(4), 306-327. <a
href="http://dx.doi.org/10.1111/j.1747-0285.200
8.00642.x">[More Information]</a>
Hinton, T., Chebib, M., Johnston, G. (2008).
Enantioselective actions of
4-amino-3-hydroxybutanoic acid and
(3-amino-2-hydroxypropyl)methylphosphinic
acid at recombinant GABA(C) receptors.
Bioorganic and Medicinal Chemistry Letters: the
tetrahedron journal for research at the interface
of chemistry and biology, 18(1), 402-404. <a
href="http://dx.doi.org/10.1016/j.bmcl.2007.10.0
19">[More Information]</a>
Fernandez, S., Mewett, K., Hanrahan, J., Chebib,
M., Johnston, G. (2008). Flavan-3-ol derivatives
are positive modulators of GABA(A) receptors
with higher efficacy for the alpha(2) subtype and
anxiolytic action in mice. Neuropharmacology,
55(5), 900-907. <a
href="http://dx.doi.org/10.1016/j.neuropharm.20
08.06.069">[More Information]</a>
Kumar, R., Chebib, M., Hibbs, D., Kim, H.,
Johnston, G., Salam, N., Hanrahan, J. (2008).
Novel gamma-aminobutyric acid rho(1) receptor
antagonists; Synthesis, pharmacological activity
and structure-activity relationships. Journal of
Medicinal Chemistry, 51(13), 3825-3840. <a
href="http://dx.doi.org/10.1021/jm7015842">[M
ore Information]</a>
Carland, J., Johnston, G., Chebib, M. (2008).
Relative impact of residues at the intracellular
and extracellular ends of the human GABA(C)
rho1 receptor M2 domain on picrotoxinin
activity. European Journal of Pharmacology,
580(1), 27-35. <a
href="http://dx.doi.org/10.1016/j.ejphar.2007.10.
036">[More Information]</a>
2007
Chebib, M., Hanrahan, J., Kumar, R., Mewett,
K., Morriss, G., Wooller, S., Johnston, G. (2007).
(3-Aminocyclopentyl)methylphosphinic acids:
Novel GABA(C) receptor antagonists.
Neuropharmacology, 52(3), 779-787. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17098260">[More Information]</a>
Small, D., Maksel, D., Kerr, M., Ng, J., Hou, X.,
Chu, C., Mehrani, H., Unabia, S., Azari, M.,
Loiacono, R., Chebib, M., et al (2007). The
β-amyloid protein of Alzheimer's disease binds
to membrane lipids but does not bind to the a7
nicotinic acetylcholine receptor. Journal of
Neurochemistry, 101(6), 1527-1538. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17286584">[More Information]</a>
2006
Hanrahan, J., Mewett, K., Chebib, M., Matos, S.,
Eliopoulos, C., Crean, C., Kumar, R., Burden, P.,
Johnston, G. (2006). Diastereoselective synthesis
of (+/-)-(3-aminocyclopentane)alkylphosphinic
Publications for Mary Collins
acids, conformationally restricted analogues of
GABA. Organic and Biomolecular Chemistry,
4(13), 2642-2649. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=16791329">[More Information]</a>
Halliday, J., Chebib, M., Turner, P., McLeod, M.
(2006). Double-Mannich annulation of cyclic
ketones using N,N-bis(ethoxymethyl) alkylamine
reagents. Organic Letters, 8(15), 3399-3401. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=16836415">[More Information]</a>
investigation into agonist binding at GABA C
receptors. Computational and Theoretical
Chemistry, 755, 81-89.
Barker, D., Lin, D., Carland, J., Chu, C., Chebib,
M., Brimble, M., Savage, G., McLeod, M.
(2005). Methyllycaconitine analogues have
mixed antagonist effects at nicotinic
acetylcholine receptors. Bioorganic and
Medicinal Chemistry, 13(14), 4565-4575. <a
href="http://dx.doi.org/10.1016/j.bmc.2005.04.0
54">[More Information]</a>
Chebib, M., Hanrahan, J., Johnston, G., Kumar,
R. (2005). Patent No. 6962907.
Crittenden, D., Park, A., Qiu, J., Silverman, R.,
Duke, R., Johnston, G., Jordan, M., Chebib, M.
(2006). Enantiomers of cis-constrained and
flexible 2-substituted GABA analogues exert
opposite effects at recombinant GABA(C)
receptors. Bioorganic and Medicinal Chemistry,
14(2), 447-455. <a
href="http://dx.doi.org/10.1016/j.bmc.2005.08.0
37">[More Information]</a>
Crittenden, D., Chebib, M., Jordan, M. (2005).
Stabilization of zwitterions in solution: GABA
analogues. The Journal of Physical Chemistry
Part A: Molecules, Spectroscopy, Kinetics,
Environment and General Theory, 109(18),
4195-4201. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=16833745">[More Information]</a>
Huang, S., Duke, R., Chebib, M., Sasaki, K.,
Wada, K., Johnston, G. (2006). Mixed
antagonistic effects of bilobalide at rho(1)
GABA(C) receptor. Neuroscience, 137(2),
607-617. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=16300902">[More Information]</a>
Crittenden, D., Kumar, R., Hanrahan, J., Chebib,
M., Jordan, M. (2005). Stabilization of
zwitterions in solution: Phosphinic and
phosphonic acid GABA analogues. The Journal
of Physical Chemistry Part A: Molecules,
Spectroscopy, Kinetics, Environment and
General Theory, 109(37), 8398-8409. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=16834233">[More Information]</a>
Johnston, G., Hanrahan, J., Chebib, M., Duke,
R., Mewett, K. (2006). Modulation of Ionotropic
GABA Receptors by Natural Products of Plant
Origin. In S.J. Enna (Eds.), GABA, (pp.
285-316). United States: Academic Press. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=17175819">[More Information]</a>
Johnston, G., Hanrahan, J., Chebib, M., Duke,
R., Mewett, K. (2006). Modulation of ionotropic
GABA receptors by natural products of plant
origin. Advances in Pharmacology, 54, 285-316.
2005
Hall, B., Chebib, M., Hanrahan, J., Johnston, G.
(2005). 6-Methylflavanone, a more efficacious
positive allosteric modulator of
gamma-aminobutyric acid (GABA) action at
human recombinant alpha2beta2gamma2L than
at alpha1beta2gamma2L and alpha1beta2
GABA(A) receptors expressed in Xenopus
oocytes. European Journal of Pharmacology,
512(2-3), 97-104. <a
href="http://www.ncbi.nlm.nih.gov/entrez/query.
fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract
&list_uids=15840393">[More Information]</a>
Crittenden, D., Chebib, M., Jordan, M. (2005). A
quantitative structure-activity relationship
2004
Carland, J., Moorhouse, A., Barry, P., Johnston,
G., Chebib, M. (2004). Charged Residues At The
2' Position Of Human GABAc �?1 Receptors
Invert Ion Selectivity And Influence Open State
Probability. Journal of Biological Chemistry,
279(52), 54153-54160.
Crittenden, D., Thompson, K., Chebib, M.,
Jordan, M. (2004). Efficiency Considerations In
The Construction Of Interpolated Potential
Energy Surfaces For The Calculation Of
Quantum Observables By Diffusion Monte
Carlo. The Journal of Physical Chemistry Part
A: Molecules, Spectroscopy, Kinetics,
Environment and General Theory, 121(20),
9844-9854.
Hall, B., Chebib, M., Hanrahan, J., Johnston, G.
(2004). Flumazenil-independent positive
modulation of g-aminobutyric acid action by
6-methylflavone at human recombinant a1h2g2L
and a1h2 GABAA receptors. European Journal
of Pharmacology, 491(1), 1-8. <a
href="http://dx.doi.org/10.1016/j.ejphar.2004.03.
014">[More Information]</a>
Chebib, M. (2004). Gabac Receptor Ion Channel.
Publications for Mary Collins
Clinical and Experimental Pharmacology and
Physiology, 31, 800-804.
Chebib, M. (2004). GABAC receptor ion
channels. Annual Scientific Meeting of ASCEPT
2003, Australia: Blackwell Publishers.
Huang, S., Duke, R., Chebib, M., Sasaki, K.,
Wada, K., Johnston, G. (2004). Ginkgolides,
Diterpene Trilactones Of Ginkgo Biloba, As
Antagonists At Recombinant
Alpha1Beta2Gamma2L Gabaa Receptors.
European Journal of Pharmacology, 494(2-3),
131-138. <a
href="http://dx.doi.org/10.1016/j.ejphar.2004.04.
051">[More Information]</a>
Chebib, M., Hanrahan, J., Mewett, K., Duke, R.,
Johnston, G. (2004). Ionotropic Gaba Receptors
As Therapeutic Targets For Memory And Sleep
Disorders. Annual Reports in Medicinal
Chemistry, 39(1), 13-23.
Carland, J., Moore, A., Hanrahan, J., Mewett, K.,
Duke, R., Johnston, G., Chebib, M. (2004).
Mutations Of The 2' Proline In The M2 Domain
Of The Human Gabac Rho1 Subunit Alter
Agonist Responses. Neuropharmacology, 46,
770-781.
Small, D., Fodero, L., Losic, D., Chu, C.,
Aguilar, M., Martin, L., Chebib, M. (2004). Role
of Aβ and the α7 nicotinic acetylcholine receptor
in regulating synaptic plasticity in Alzheimer's
disease. International Journal of Peptide
Research and Therapeutics, 10(5-6), 401-404. <a
href="http://dx.doi.org/10.1007/BF02442570">[
More Information]</a>
Crittenden, D., Chebib, M., Jordan, M. (2004).
Stabilization of Zwitterions in Solution:
γ-Aminobutyric Acid (GABA). The Journal of
Physical Chemistry Part A: Molecules,
Spectroscopy, Kinetics, Environment and
General Theory, 108(1), 203-211.
Duke, R., Chebib, M., Hibbs, D., Mewett, K.,
Johnston, G. (2004). Synthesis And Resolution
Of 2-Methyl Analogues Of GABA.
Tetrahedron-Asymmetry, 15(11), 1745-1751.
Campbell, E., Chebib, M., Johnston, G. (2004).
The Dietary Flavonoids Apigenin And
(-)-Epigallocatechin Gallate Enhance The
Positive Modulation By Diazepam Of The
Activation By GABA Of Recombinant
GABA(A) Receptors. Biochemical
Pharmacology, 68(8), 1631-1638. <a
href="http://dx.doi.org/10.1016/j.bcp.2004.07.02
2">[More Information]</a>
2003
Krehan, D., Frølund, B., Ebert, B., Nielsen, B.,
Krogsgaard-Larsen, P., Johnston, G., Chebib, M.
(2003). Aza-THIP and related analogues of THIP
as GABAc antagonists. Bioorganic and
Medicinal Chemistry, 11(23), 4891-4896. <a
href="http://dx.doi.org/10.1016/j.bmc.2003.09.0
16">[More Information]</a>
Huang, S., Duke, R., Chebib, M., Sasaki, K.,
Wada, K., Johnston, G. (2003). Bilobalide, a
sesquiterpene trilactone from ginkgo biloba, is an
antagonist at recombinant a1b2y2l GABAA
receptors. European Journal of Pharmacology,
464(1), 1-8.
Chebib, M., Duke, R., Duke, C., Connor, M.,
Mewett, K., Johnston, G. (2003). Convulsant
actions of Calycanthine. Toxicology and Applied
Pharmacology, 190(1), 58-64.
Johnston, G., Chebib, M., Hanrahan, J., Mewett,
K. (2003). GABAc receptors as drug targets.
CNS and Neurological Disorders, 2(4), 260-268.
Krehan, D., Frølund, B., Krogsgaard-Larsen, P.,
Kehler, J., Johnston, G., Chebib, M. (2003).
Phosphinic, phosphonic and seleninic acid
bioisosteres of isonipecotic acid as novel and
selective GABAc receptor antagonists.
Neurochemistry International, 42(7), 561-565.
Hanrahan, J., Chebib, M., Davucheron, N., Hall,
B., Johnston, G. (2003). Semisynthetic
preparation of amentoflavone: a negative
modulator at gabaa receptors. Bioorganic and
Medicinal Chemistry Letters: the tetrahedron
journal for research at the interface of chemistry
and biology, 13(14), 2281-2284.
2002
Huang, S., Duke, R., Chebib, M., Johnston, G.,
Sasaki, K., Wada, K. (2002). Bilobalide, from
Ginkgo biloba, and enhancement of wild type
alpha-1 beta-2gamma-2l GABAa receptors by
diazepam, pentobarbitone and a steroid. 3rd
College of Health Sciences Research
Conference, Sydney: University of Sydney.
Huang, S., Duke, R., Chebib, M., Johnston, G.,
Sasaki, K., Wada, K. (2002). Effects of
bilobalide and the sesquiterpene of Ginkgo
bilobaon GABA-mediated currents modulated by
GABAa modulators. 20th International
Australasian Winter Conference on Brain
Research.
Campbell, E., Chebib, M., Duke, R., Hall, B.,
Hanrahan, J., Johnston, G., Mewett, K. (2002).
Epigallocatechin gallate, from green tea, and
related agents as modulators of human brain
GABA receptors. 5th Australia/Japan
Symposium on Drug Design and Development.
Duke, R., Chebib, M., Duke, C., Johnston, G.,
Roufogalis, B. (2002). Ginkgo biloba - food for
the brain. New Zealand Pharmacy, , 27-33.
Huang, S., Duke, R., Chebib, M., Johnston, G.,
Sasaki, K., Wada, K. (2002). Investigation of the
Publications for Mary Collins
effects of bilobalide from Ginkgo biloba on wild
type alpha-5beta-2gamma-2l
alpha-1beta-2gamma-2l and alpha-1beta-2
GABAa receptors. Australian Health and
Meldical Research Conference.
Vien, J., Duke, R., Mewett, K., Johnston, G.,
Shingai, R., Chebib, M. (2002).
Trans-4-amino-2-methylbut-2-enoic acid
(2-MeTACA) and
(+/-)-trans-2-aminomethylcyclopropanecarboxyli
c acid ((+/-)-TAMP) can differentiate rat rho3
from human rho1 and rho2 recombinant GABA
(C) receptors. British Journal of Pharmacology,
135(4), 883-889.
2001
Hanrahan, J., Mewett, K., Chebib, M., Burden,
P., Johnston, G. (2001). An improved, versatile
synthesis of the GABAc antagonists
(1,2,5,6-tetrahydropyridin-4-yl)methylphosphini
c acid (TPMPA) and
(piperidin-4-yl)methylphosphinic acid (P4MPA).
Royal Chemical Society. Journal. Perkin
Transactions 1, 1, 2389-2392.
Chebib, M. (2001). Novel agents acting on
GABAc receptors: potenial cognitive enhancers.
Chemistry in Australia, 69, no 9, 19-21.
Chebib, M., Duke, R., Allan, R., Johnston, G.
(2001). The effects of cyclopentane and
cyclopentene analogues of GABA at
recombinant GABAc receptors. European
Journal of Pharmacology, 430, 185-192.